Abstract: A patient monitor includes an interface configured to be connectable to a first sensor to measure first physiological information and to a second sensor to measure second physiological information, and a controller configured to actuate the second sensor to start a process for measuring the second physiological information in response to the first physiological information turning abnormal, the first physiological information being calculated based on a sensor signal acquired from the first sensor.

Abstract: Medical device alarm systems and methods of use including a medical device, a processor, a memory communicatively coupled to the processor, and machine readable instructions stored in the memory may perform at least the following when the instructions are executed by the processor: detect a predefined medical device condition associated with the medical device to determine a detected predefined medical device condition, and generate a high frequency sound alarm based on the detected predefined medical device condition. The high frequency sound alarm may be configured to be tailored to a living entity and be in an upper sound register such that the high frequency sound alarm is configured to alert the living entity capable of hearing the upper sound register of the detected predefined medical device condition.

Abstract: A method and system for adjusting the AUC limit threshold to reduce the number of false alarms. In one embodiment the method includes the steps of: defining a AUC limit threshold; defining a saturation limit threshold for a desired oxygen saturation level; periodically measuring a patient's measured oxygen saturation level over time; calculating the difference between the patient's measured oxygen saturation and defined saturation limit threshold; summing the differences between the patient's measured oxygen saturation and defined saturation limit threshold over a time interval wherein the patient's measured oxygen saturation is less than defined saturation limit threshold, wherein the summation defines a measured AUC; comparing the measured AUC over the time interval against the defined AUC limit threshold; determining regions in which the measured AUC exceeds the defined AUC limit threshold; and adjusting the AUC limit threshold.

Abstract: Apparatus and methods for providing dynamic displays. In one embodiment, a method is provided wherein health parameters having goals associated therewith are displayed; data relating to the health parameters is received and the display is incremented according to a progress of the user toward the goal. When collection of the data is completed, it is determined whether a current value of a first one of the health parameters within a predetermined range of the goal associated therewith. When the current value of the first one of the health parameters is within the range, a portion of the display relating thereto is upgraded. When the current value of all of the health parameters is within the range, the entire display is upgraded. The display upgrades may comprise display of an animation and/or using color, light, and/or flashing to simulate a shining or shimmering of the display.

Abstract: A control unit for a medical device wherein the control unit comprises a pump, a conduit and control means for controlling the flow of fluid from the pump through the conduit; and wherein the conduit is a rigid internal passage located in the control unit.

Abstract: Systems and methods for x-ray imaging a patient's breast in combinations of dual-energy, single-energy, mammography and tomosynthesis modes that facilitate screening for and diagnosis of breast abnormalities, particularly breast abnormalities characterized by abnormal vascularity.

Abstract: A method of an image processing apparatus for identifying a type of adipose body tissue within a subject, based on performing a spectral computed tomography (CT) scan of a region of interest of the subject; and using a combination of different image processing techniques to differentiate between at least two adipose tissue types within the region of interest.

Abstract: The ultrasonic CT device includes: a first water tank configured such that an object is inserted therein, the first water tank being filled with a medium through which an ultrasonic wave passes; a ring array that irradiates an ultrasonic wave to the object and detects an ultrasonic wave reflected by the object while moving on an outer surface of the first water tank; and a signal processing unit that generates a tomographic image of the object based on a signal obtained by the ring array. The ultrasonic CT device further includes: a second water tank that houses the first water tank and the ring array; and a lid having a hole or a notch which is provided on a side of the object in the second water tank and which drains the medium.

Abstract: Provided herein are x-ray imaging systems, methods of x-radiography, and methods of manufacture of collimators suitable for use in x-ray imaging systems and methods of x-radiography. The systems, methods and devices proposed here may assist in providing for improved magnification of x-rays in an x-ray imaging system with improved image quality compared to known systems. It may find applications in a variety of x-ray applications, for example x-ray CT (Computed Tomography) and 2D projectional radiography for e.g. non-destructing testing purposes.

Abstract: Provided herein are, inter alia, methods and systems for detecting mucus in the lungs of a subject. Aspects provide methods and systems for the diagnosis, prognosis, characterization, detection, and treatment of asthma, chronic obstructive pulmonary disease, and type 2 inflammation.

Abstract: A method includes generating spectral projection data of a subject, including at least first spectral projection data corresponding to a first energy range and second spectral projection data corresponding to a second energy range, wherein the first and the second energy range are different. The method further includes constructing an image from a combination of the spectral projection data, and constructing a set of basis images for the 5 energy ranges and from the spectral projection data. The method further includes constructing a multi-dimensional histogram from the set of basis images, wherein the multi-dimensional histogram includes at least two axes, a first corresponding to a first basis component and a second corresponding to a second basis component, and the multi-dimensional histogram includes a set of clusters, including one cluster for each material 10 represented in the spectral projection data.

Abstract: To generate images, in which a first row area of a multiple-row detector is illuminated with a first X-ray spectrum and a second row area of the multiple-row detector, trailing in the direction of travel, is illuminated with a second X-ray spectrum, image data is recorded at a pitch chosen such that one slice image can be reconstructed in each case for a sectional position for the first and the second row area. Correspondingly, for the sectional position, the respective slice image for the first and the second row area is reconstructed. For a third row area, illuminated with the first and the second X-ray spectrum, a reference sectional image is reconstructed as a slice image. To generate motion-reduced first and second spectral images assigned to the first and second row area respectively, the slice images of the first and second row areas are registered to the reference sectional image.

Abstract: For a multi-modal emission tomography system, an improved control system increases the likelihood of optimal image quality, satisfaction of physician goals, and/or avoids repetition in scanning and the corresponding increase in dose burden. The control system is divided into two or more arrangements. One arrangement receives goal information and outputs reconstruction settings and generic scan settings to satisfy the goal information. Another arrangement converts the generic scan settings to emission tomography system-specific scan settings, which are used to detect emissions. The separation of the arrangements allows independent operation so that different system-specific conversions may be used for different systems.

Abstract: A mobile X-ray apparatus includes: an X-ray radiation device; a controller configured to control the X-ray radiation device; a power supply configured to supply operating power to the X-ray radiation device and the controller via a lithium ion battery and control overcurrent occurring during X-ray emission by the X-ray radiation device; and a charger configured to charge the power supply. Each of the controller, the power supply, and the charger is embodied in a physically separate module, and each of the power supply and the charger is encased in a metal case.

Abstract: A medical imaging device includes an x-ray source disposed at a first end of an arm, and an x-ray detector disposed at a second end of the arm opposite of the x-ray source. At least one of the x-ray source, the x-ray detector, and a portion of the arm are selectively adjustable with respect to the arm.

Abstract: An apparatus (e.g., an imaging system) includes a circuit, including: a p-i-n diode having a cathode coupled to a cathode bias voltage or ground; a charge transistor having a first source/drain terminal coupled to an anode of the diode; a storage capacitor having a first terminal coupled to a second source/drain terminal of the charge transistor and a second terminal coupled to the cathode; an amplification transistor having a gate terminal coupled to the first terminal of the storage capacitor and a first source/drain terminal coupled to a reference voltage; a read transistor having a first source/drain terminal coupled to a second source/drain terminal of the amplification transistor; a data line having a first terminal coupled to a second source/drain terminal of the read transistor; and a readout circuit coupled to a second terminal of the data line, providing an output voltage corresponding to charge on the storage capacitor.

Abstract: Systems and methods for enhanced diagnosis of transthyretin-related cardiac amyloidosis in a subject are disclosed. The systems and methods may use both SPECT imaging data as well as an anatomical imaging data, such as computed tomography (CT) data, to produce a combined image. Within the combined image, the radiotracer uptake between two volumes of interests are compared, one of which may represent the left ventricle of the subject and the other may represent the blood pool retention of the subject. Combining the anatomical imaging data with SPECT data enables better anatomical delineation and helps in avoiding areas with coronary or lymph node calcifications and overlying soft tissue and bony pathologies.

Abstract: Embodiments access a set of radiological images acquired from a population of subjects, where a member of the set of radiological images includes a left atrium (LA) region; construct a statistical shape differential atlas from the images; generate a template LA model from the statistical shape differential atlas, where the template LA model includes a site of interest (SOI); acquire a pre-ablation radiological image of a region of tissue in a patient demonstrating atrial fibrillation (AF) pathology; generate a patient LA model from the pre-ablation image; compute a deformation field that registers the SOI to the patient LA model using deformable registration; compute a patient feature vector based on the deformation field; generate an AF probability score for the patient based on the feature vector; generate a classification of the patient based, at least in part, on the AF probability score; and display the classification or the AF probability score.

Abstract: A radiography system includes a radiography apparatus including two radiation detectors and a console that corrects scattered ray components of a first radiographic image generated by the radiography apparatus, using first correction data, corrects scattered ray components of a second radiographic image, using second correction data different from first correction data, and performs an energy subtraction process, using the corrected first and second radiographic images.

Abstract: An image processing apparatus includes: an acquisition unit that acquires a radiographic image generated by a radiation detector irradiated with radiation from a radiography apparatus including the radiation detector in which plural pixels, each of which includes a conversion element that generates a larger amount of charge as it is irradiated with a larger amount of radiation, are arranged; and a correction unit that corrects scattered ray components caused by scattered rays of the radiation included in the radiographic image, using correction data for correcting scattered rays which is associated with each of plural regions in the radiographic image.

Abstract: A method is disclosed for adjusting a collimator of an X-ray source. In an embodiment, the method includes detecting an arrangement of an X-ray detector with respect to the X-ray source; automatically determining an adjustment for the collimator based on the detected position of the X-ray detector with respect to the X-ray source; and automatically adjusting the collimator based on the determined adjustment for the collimator. An X-ray device and computer readable medium are also disclosed.

Abstract: A radiographic imaging system includes an irradiating apparatus, a first clock, a radiographic imaging apparatus, a second clock and a hardware processor. The irradiating apparatus generates radiation. The first clock keeps time and works with the irradiating apparatus. The radiographic imaging apparatus generates image data based on received radiation. The second clock keeps time and works with the radiographic imaging apparatus. The hardware processor (i) obtains a clock value of the first clock at a predetermined time point and a clock value of the second clock at the predetermined time point respectively as first clock information and second clock information, (ii) makes a determination as to whether a specific condition is met based on the obtained first clock information and the obtained second clock information, and (iii) in response to the specific condition being met, performs a specific output.

Abstract: A synchronization signal transmitter is configured to be capable of storing unique identification information that can identify the synchronization signal transmitter and transmitting the identification information to a radiation irradiation apparatus and a radiation imaging apparatus. The radiation irradiation apparatus or the radiation imaging apparatus includes a hardware processor that determines whether or not the identification information that has been received by the radiation irradiation apparatus and the identification information received by the radiation imaging apparatus are in agreement with each other.

Abstract: An ultrasonic diagnostic apparatus includes a probe configured to irradiate an ultrasonic signal to an object and receive the ultrasonic signal reflected from the object; a pressure device configured to contract or expand a blood vessel of the object and is divided into a plurality of regions; and a controller configured to operate in one region of the plurality of regions to generate an image related to the blood vessel of the object and sequentially operate in other regions of the plurality of regions.

Abstract: Disclosed herein is a medical apparatus. The medical apparatus includes an ultrasound probe, a handpiece, and a pedal member. The ultrasound probe is configured to be externally positioned on a facial area of a patient. The handpiece has a guidewire and a balloon catheter. The balloon catheter is configured to be in fluid communication with a fluid source. The pedal member is configured to operably manipulate the fluid source. The ultrasound probe is configured to position the balloon catheter to a nasal ostium of the patient for dilation of the nasal ostium through the guidewire.

Abstract: A fusion imaging system co-registers and fuses real time ultrasound images with reference images such as those produced by MRI or CT imaging. In an illustrated implementation, previously acquired CT or MRI or ultrasound images are loaded into the system. An ultrasound system is operated in conjunction with a tracking system so that the ultrasound probe and images can be spatially tracked. A computerized image processor registers the probe position with a reference image of the anatomy being scanned by the probe and determines whether the probe appears to be inside the skin line of the subject. If that is the case it is due to probe compression of the subject, and the reference image is modified to locate the skin line in the reference image in front of the ultrasound probe. The modified reference images can then be readily co-registered and fused with the ultrasound images produced by the probe.

Abstract: An ultrasound probe and ultrasound diagnostic apparatus that achieve high transmission/reception sensitivity and wide frequency band are provided. The ultrasound probe includes a pMUT array in which a plurality of pMUTs are arranged. The pMUTs include first pMUTs for ultrasound transmission and pMUTs for ultrasound wave reception having a structure different from that of the first pMUTs. The cell region of each first pMUT and the cell region of each second pMUT are separated from each other in the ultrasound wave radiation plane.

Abstract: A transducer assembly includes: a microelectromechanical systems (MEMS) die including a plurality of piezoelectric elements; a complementary metal-oxide-semiconductor (CMOS) die electrically coupled to the MEMS die by a first plurality of bumps and including at least one circuit for controlling the plurality of piezoelectric elements; and a package secured to the CMOS die by an adhesive layer and electrically connected to the CMOS die.

Abstract: A ultrasound probe according to this invention is provided with: a first dry film resist having a plurality of first apertures formed in an array shape, and respectively supporting the piezoelectric elements in close contact with a rim part of each of the first apertures in a state of partly exposing the function elements; a second dry film resist laminated on the first dry film resist, and also having second apertures respectively enclosing each of the function elements, the second dry film resist being of a thickness equivalent to that of each of the function elements; and a third dry film resist laminated on the second dry film resist, and also having third apertures, and respectively sandwiching each of the piezoelectric elements with the first dry film resist in a state of partly exposing the piezoelectric elements in close contact with a rim part of each of the third apertures.

Abstract: An ultrasound observation device includes a processor including hardware, the processor being configured to execute: setting any one of processing modes regarding multiple different processes performed on an ultrasound image by a user; performing, based on a command signal output from a touch-pad in accordance with a change in a touch position of a touching object, a process corresponding to the set processing mode, the ultrasound observation device; and determine, based on the set processing mode, a control to be performed out of a first control to stop a process on the ultrasound image and a second control to perform a predetermined process on the ultrasound image when it is detected that the touching object moves away from the touch-pad.

Abstract: An assisted detection system of breast tumor includes an image capturing unit and a non-transitory machine readable medium. The non-transitory machine readable medium storing a program which, when executed by at least one processing unit, determines a breast tumor type of the subject and predicts a probability of a tumor location of the subject. The program includes a reference database obtaining module, a first image preprocessing module, an autoencoder module, a classifying module, a second image preprocessing module and a comparing module.

Abstract: A image fusion workstation for an image-based fusion of an endoscopic image (33) of an anatomical region generated by an endoscope (31) and an ultrasound image (43) of the anatomical region generated by a laparoscopic ultrasound probe (41). The image fusion workstation employs an image fusion controller (50) controlling the fusion between the endoscopic image (33) and the ultrasound image (43) based on an image transformation between an endoscopic image space of the endoscope (31) and an ultrasound image space of the laparoscopic ultrasound probe (41) derived from a detection by the image fusion controller (50) of the laparoscopic ultrasound probe (41) within a field-of-view (32) of the endoscope (31) of the anatomical region. The image fusion workstation further employs a display controller (60) controlling a display of the fusion by the image fusion controller (50) of the endoscopic image (33) and the ultrasound image (43).

Abstract: Provided herein are methods of detecting and measuring disease-associated analytes such as proteins and antibodies in a sweat sample. Also provided are methods of determining and monitoring the disease state or physiological condition of a subject using small sweat samples.

Abstract: A system and method for enhanced navigation for use during a surgical procedure including planning a navigation path to a target using a first data set of computed tomography images previously acquired; navigating a marker placement device to the target using the navigation path; placing a plurality of markers in tissue proximate the target; acquiring a second data set of computed tomography images including the plurality of markers; planning a second navigation path to a second target using the second data set of computed tomography images; navigating a medical instrument to a second target; capturing fluoroscopic data of tissue proximate the target; and registering the fluoroscopic data to the second data set of computed tomography images based on marker position and orientation within the real-time fluoroscopic data and the second data set of computed tomography images.

Abstract: A powered medical device includes electronic components on a circuit board embedded within the body of a plug for connecting the device with a control apparatus. The medical device may be repaired or refurbished without the need to access the embedded circuit board through the use of a supplemental circuit board installed into the open end of the plug adjacent the plug pins. The supplemental circuit board may include a variety of electronic components, including fuses or non-volatile memory.

Abstract: The present invention a liquid dispenser comprising a housing defining a chamber for releasably receiving an ampoule of a liquid to be dispensed, the body further defining an outlet to enable the liquid to be dispensed from the chamber; an actuator displaceable relative to the housing; wherein a section of the housing is adapted to permit a least a section of the actuator to be displaced into the chamber to apply a force, in use, to the ampoule.

Abstract: Shapeable articles, kits including one or more of the shapeable articles, and methods of making and/or using the shapeable articles. The shapeable articles include a shapeable member that can be shaped or manipulated into three-dimensional shapes without the use of tools and hold those shapes after removal of the force required to achieve the shape. The shapeable articles could have a variety of uses including use as surgical retractors to move and/or restrain non-target tissue and/or organs to improve access to the target tissue and/or organs.

Abstract: A surgical apparatus configured to be placed in the musculoskeletal system to precisely separate a first bone from a second bone. The surgical apparatus has one or more sensors to measure one or more parameters and supports one or more bone cuts for installing a prosthetic component. The surgical apparatus has three distraction mechanisms configured to increase or decrease a height between a first support structure and a second support structure. A tilt mechanism comprises at least one of the three distraction mechanisms. Each distraction mechanism is supported by at least two guide shafts such that movement of each distraction mechanism is aligned by the corresponding at least two guide shafts and loading is supported by the corresponding at least two guide shafts.

Abstract: A balloon dilator device, comprising an annularly shaped, cylindrical type structure having walls that are expandable from a radially collapsed state to a radially expanded state by inflation of a balloon inserted within the annular structure. Once the walls have been expanded, they remain in the expanded state even if the balloon is deflated, because the radially expanded state is a state of minimum mechanical potential energy, and in order to return to the collapsed state, the structure would have to pass a state of higher potential energy. The device walls require sufficient stiffness in their longitudinal direction to enable the device to be pushed into a minimally invasive incision made in the subject. This device stiffness can be achieved either by its mechanical material properties, or by its substantially closed wall structure, or by use of a stiff protector sheath used to protect the walls during insertion.

Abstract: A cannula assembly having a retention member and a method of manufacture of the cannula assembly is provided. The cannula assembly includes a cannula and a sleeve disposed around the cannula from a proximal end to a distal end. The sleeve can be pre-formed by a stretch blow molding process then advanced over the cannula. The sleeve includes an inflatable balloon and an annular ring distal the inflatable balloon. The cannula includes an annular recess. The annular ring is sized to have an interference fit with the annular recess.

Abstract: An all-suture anchor for attaching soft tissue to bone while creating an interference fit within a bone hole, and a deployment device for the all-suture anchor. The all-suture anchor includes an anchor body having first and second ends. The second end is folded toward the first end, creating a looped distal end of the anchor body, while the first and second ends of the anchor body form a proximal end. The anchor body is composed of a first material having a first density. A passing filament, of a second (different) density, is woven through the anchor body at passing locations such that a pair of free ends of the passing filament extends from the proximal end of the anchor body. The all-suture anchor additionally includes a binding filament bound axially at the proximal end of the anchor body around the first end and the second end of the anchor body.

Abstract: The present invention describes a bio-medically compatible gripping device capable of radial collapse in accordance with the shrinkage of a nylon or other polymeric material cored surgical cable undergoing tension while maintaining a firm grip for prolonged periods of time. It provides a gripping device capable of maintaining a non-damaging hold on the outer surface of a slippery delicate cable under high tension for a sufficient time in which the healing process can occur.

Abstract: A method of coupling a first portion of an anatomy to a second portion of the anatomy includes coupling first and second bones of the anatomy with a bone-tendon-bone implant. The bone-tendon-bone implant has a first bone end, a second bone end and a replacement tendon between the first and second bone ends. The first and second bone ends are positioned in corresponding first and second bores of the first and second bones. The first bone end is secured to the first bone with a first bone anchor. A second anchor coupled to the bone-tendon-bone implant is passed through and outside the second bore. The second anchor is coupled to an adjustable suture construct having two adjustable suture loops. Tensioning at least one of first and second ends of the adjustable suture construct tensions the replacement tendon and positions the first bone relative to the second bone.

Abstract: A suture package includes a suture tray and a suture thread. The suture track has a first housing, a second housing receive against the first housing, a storage space defined between the first and second housings, and a thread shelf positioned within the storage space. The suture thread is at least partially contained within the storage space and has a first portion extending toward the thread shelf and a second portion extending toward the thread shelf such that the first and second portions of the suture thread intersect at the thread shelf. The suture thread also has a third portion between the first and second portions received against the thread shelf such that the thread shelf holds the suture thread to define a preformed thread bend for manipulating the first portion of the suture thread relative to the second portion of the suture thread via the preformed thread bend.

Abstract: In one embodiment, a suture attachment catheter configured to repair a heart valve by inserting a suture in a valve leaflet of a beating heart of a patient includes a handle control, a flexible catheter body, and a suture attachment assembly at a distal end of the catheter body. The suture attachment assembly can include a rail between a distal clamping jaw hingedly attached to the rail, and a proximal clamping jaw. One of the proximal clamping jaw or distal clamping jaw can be selectively slideable with respect to the other on the rail using a jaw actuator of the control handle to adjust a distance between the proximal clamping jaw and the distal clamping jaw. A needle can be selectively slideable within the catheter body by using a needle actuator of the proximal handle control to penetrate a valve leaflet and insert a suture through the valve leaflet when the valve leaflet is captured between the proximal clamping jaw and the distal clamping jaw.

Abstract: Suture clip deployment devices for applying suture clips to sutures are described. Some embodiments can include a generally tubular main body and a vacuum port located at the distal end, a hollow inner body longitudinally slidable within the main body and extending from the main body at its distal end, and a suture recess located in the generally tubular main body. At least one suture clip configured to frictionally fit on an outer surface of the inner body is deployed during use. Clip deployment can occur after a vacuum source is applied to the device so as to draw the suture into the device. The suture lines can be retrieved through the suture recess, and the device can be actuated so as to deliver the suture clip off the delivery device and onto the suture, locking the suture in place.

Abstract: The presently disclosed subject matter provides systems and methods for performing minimally invasive surgery. A laparoscopic device for performing minimally invasive surgery can include a mesh configured to be affixed to a fascial tissue to reinforce the fascial tissue. The mesh can be attached to the laparoscopic device before the mesh reaches the fascial tissue. The laparoscopic device can also include a telescoping arm configured to deliver the mesh to the fascial tissue. The telescoping arm can be further configured to position the mesh at the fascial tissue by releasing the mesh from the laparoscopic device.

Abstract: The present invention is directed to a surgical instrument with a robotics system, a memory device and an end effector having an elongate channel, knife position sensor(s) and a firing bar coupled to a knife. In response to drive motions initiated by the robotics system, the firing bar may translate within the elongate channel. As the firing bar translates, the sensor(s) transmit a signal to the memory device. The position of the knife may be determined from the output signals and may be communicated to the robotics system or instrument user. The sensors may be Hall Effect sensors.

Abstract: The present invention is directed to a surgical instrument with a robotics system, a memory device and an end effector having an elongate channel, knife position sensor(s) and a firing bar coupled to a knife. In response to drive motions initiated by the robotics system, the firing bar may translate within the elongate channel. As the firing bar translates, the sensor(s) transmit a signal to the memory device. The position of the knife may be determined from the output signals and may be communicated to the robotics system or instrument user. The sensors may be Hall Effect sensors.

Abstract: A surgical instrument includes a shaft, an end effector extending distally from the shaft, and a housing extending proximally from the shaft. The housing includes a motor configured to generate at least one motion to effectuate the end effector, and a power source configured to supply power to the surgical instrument, wherein the power source includes a casing, a data storage unit, and a deactivation mechanism configured to interrupt access to data stored in the data storage unit. In addition, the power source includes a battery pack and a deactivation mechanism configured to deactivate the battery pack if the casing is breached.