Abstract: A breathing device including a housing portion and a mouthpiece portion. The housing portion has external and internal surfaces and a distal end portion and a proximal end portion. The mouthpiece portion has external and internal surfaces and includes a flared portion having a narrower distal end portion and extending to a wider proximal end portion, and the flared portion includes a depressed portion adjacent to the wider proximal end portion and configured to contact lips of a user.

Abstract: A sensor-based quantification and analysis system includes an input device including a plurality of sensors that generate an input based on a force. The input device also includes a transmission device that transmits force information based on the input. The system also includes an output device that receives the force information. A processing unit selects, for each of the plurality of sensors, one of a plurality of levels of a likelihood of tissue damage based on the force and a predetermined time period. Further, the output device includes a display that presents or logs the one of the plurality of levels of the likelihood of tissue damage for each of the plurality of sensors.

Abstract: Methods, systems, and computer program products are provided for measuring and analyzing muscle flexibility to infer a change in gait. Muscle flexibility measurements are obtained using at least one sensor of a device attached to a body of a user. A flexibility quotient is calculated based on the obtained muscle flexibility measurements, user information, a type of activity, a workout duration and baseline data. A change in flexibility based on the calculated flexibility quotient and a baseline flexibility quotient is determined. A change in gait is inferred based on the determined change in flexibility and is reported to the user.

Abstract: A person support apparatus, such as a bed, cot, stretcher, or the like, includes an exit detection system that utilizes an occupant motion parameter to determine whether to issue an alert or not. The motion parameter may be based on the weight and motion of the occupant. Successive positions of the occupant are determined in order to calculate a velocity of the occupant. In some embodiments, the kinetic energy of the occupant is used to determine if an alert should be issued. Objects positioned on the person support apparatus may also be detected and tracked. Auto-zeroing of a built-in scale, as well as automatic recognition of the removal, movement, and/or addition of objects is also provided.

Abstract: Provided in the present invention are a flexible electrochemical electrode, a subcutaneous continuous glucose monitoring sensor equipped with the electrochemical electrode, and a preparation method thereof. The electrode directly uses gold layers on both sides of a chemically plated film, respectively as a working electrode and a reference-counter electrode, so as to form an electrochemical two-electrode system. Petaloid platinum nanoparticles are electrodeposited on a surface of the configured working electrode as a catalytic layer; a carbon nanotube/Nafion mesh layer functions as an anti-interference layer, and is formed thereon with an enzyme biochemical sensitive layer by means of electrostatic adsorption, after crosslinking and curing in glutaraldehyde, polyurethane mass transfer is coated to limit a protection layer, so as to prepare a flexible continuous glucose monitoring sensor.

Abstract: A fully integrated small size implantable sensing device is described, which can include a sensor and an electronic circuit to interface with the sensor and communicate with an external device. Various fabrication methods for the sensing device are described, including provision of wells, created using same fabrication technology as the electronic circuit, to contain electrodes of the sensor and corresponding functionalization chemicals. Such implantable sensing device can be used for a variety of electrochemical measuring applications within a living body as well as actuation by injecting a current into the living body.

Abstract: The present disclosure provides methods and systems for providing personalized food and health management recommendations. A dietary glucose monitor may comprise a food analysis module in communication with a glucose level monitor, where the food analysis module may be configured to (1) analyze data indicative of foods consumed by a user, and (2) determine an effect of individual foods on a glucose level of the user, based on changes to the user's glucose level as measured by the glucose level monitor.

Abstract: A glucose biosensor includes a plurality of optical fibers configured for placement within the ear canal. A first optical fiber emits light into the ear canal. A plurality of other optical fibers capture and transmit the reflected light back to the glucose biosensor. A plurality of photodetectors are configured in the glucose biosensor to detect the reflected light from the plurality of optical fibers. The glucose biosensor processes the detected light from each photodetector to determine a glucose level measurement. In an embodiment, the glucose biosensor also obtains a second glucose level measurement using another method and determines a calibration for the first glucose level measurement using the second glucose level measurement.

Abstract: A biological information measurement device includes a correction unit that receives a first signal expressing a change in an amount of light of a first wavelength detected from a living body and a second signal expressing a change in an amount of light of a second wavelength detected from the living body, and corrects at least one of the first signal and the second signal to reduce a difference between an amount of change in the first signal and an amount of change in the second signal associated with a change in an amount of arterial blood of the living body, and a computing unit that computes a change in a blood oxygen concentration in the living body on a basis of the first signal and the second signal of which at least one is corrected by the correction unit.

Abstract: A biological information measurement apparatus includes a first measurement unit that measures a value representing oxygen concentration in blood of a subject, and a second measurement unit that measures, by referring to a change in the value measured by the first measurement unit, as an oxygen circulation time within a predetermined time period with an end time thereof set to be later than a restart time of breathing of a subject from holding of breathing, a time duration from the restart time to a detection time of an inflection point of the value detected after the restart time of breathing.

Abstract: A physiological information detection system may include an add-on device in electronic communication with a computing device. The add-on device includes a body and a first light filter retained in the body. The first light filter filters light emitted by the light source of the computing device. A lens is also retained in the body proximate the first light filter. The lens directs light exiting the first light filter out a surface of the first lens. The body retains a second lens that receives into a surface of the second lens light exiting the first lens. The surface of the first lens and the surface of the second lens are substantially coplanar. A second light filter is also retained in the body proximate the second lens. The sensor detects the light exiting the second light filter.

Abstract: Various technologies presented herein relate to sterile transport, storage and operation of fluid collection tubes. A plurality of sterile sample tube packages are presented, wherein each package comprises a tray (having a recessed cavity formed therein), one or more fluid collection tubes and a cover. Each cavity includes at least one compartment, wherein a collection tube can be respectively stored in each compartment. The tray and cover can be formed from medically sterile materials.

Abstract: Methods and systems are provided to identify an individual's health risk of developing a disease or disorder, and to motivate the user to adopt a behavioral change to mitigate the progression of the identified disease or disorder. An individual's medical history is analyzed to determine diseases that a user is at risk of developing, as well as positive and negative behaviors of the user relating to the disease. For a negative behavior, the system identifies a behavioral change that is to be promoted to the individual through a cohort. The system then sends notifications to the cohort, for the cohort to promote the behavioral change to the individual via a client system associated with the individual. Methods and systems are also provided to send notifications to a cohort to promote maintaining the behavioral change to reduce the likelihood that the individual will revert to former behavior.

Abstract: A control apparatus for controlling a vehicle, comprising an evaluation unit configured to evaluate a degree of interest of a passenger of the vehicle with respect to time, and a setting changing unit configured to change setting of a kinetic characteristic of the vehicle based on an evaluation result obtained by the evaluation unit.

Abstract: A method for predicting an arousal level used by a computer of an arousal level prediction apparatus that predicts an arousal level of a user includes obtaining current biological information regarding the user detected by a first sensor, calculating a current arousal level of the user on the basis of the current biological information, obtaining current environment information indicating a current environment around the user detected by a second sensor, predicting a future arousal level, which is an arousal level a certain period of time later, on the basis of the current arousal level and the current environment information, and (i) issuing a notification to the user or (ii) controlling another device, on the basis of the future arousal level.

Abstract: Systems and methods for detecting athletic performance and fatigue are disclosed herein. In one embodiment, a method for monitoring athletic performance of an athlete includes: monitoring a heart rate (HR) of the athlete by a wearable electrocardiogram (ECG) sensor carried by the athlete; determining a rate of change of the HR over a period of time; comparing the rate of change to a predetermined threshold; and based on the comparing, determining whether the athlete is fatigued.

Abstract: A method for determining neurotransmitter levels and/or neurotransmitter receptor sensitivity in an individual, comprising: determining a taste recognition profile of the individual for at least one taste modality prior and subsequent to the administration of a pharmaceutical for increasing neurotransmission; comparing the taste recognition profiles to determine a change; and comparing that change with corresponding measurements from a comparative database to determine neurotransmitter levels and/or neurotransmitter receptor sensitivity in the individual. In addition, a sample of a taste modality is provided for use in a method of diagnosis of a psychiatric, neurological, psychosomatic or physical disorder in an individual.

Abstract: A recovery evaluation apparatus includes a display that displays an image, an evaluating unit that evaluates balance of a subject who is viewing the image, a controller that, in accordance with temporal variation of an evaluation value of the balance, varies a degree of a visual stimulus provided by the image, and a recovery evaluation unit that evaluates balance recovery, the balance recovery representing balance recovery of the subject upon varying of the degree of the visual stimulus.

Abstract: A cognitive function evaluation device includes an acquisition unit that acquires body motion data representing a body motion of a person to be evaluated during walking; a calculation unit that calculates a displacement of a body of the person to be evaluated during walking based on the acquired body motion data; and an evaluation unit that evaluates a cognitive function of the person to be evaluated based on a frequency peak representing a cycle of walking of person-to-be-evaluated obtained by performing a frequency analysis on the calculated displacement, and to output the evaluation result.

Abstract: A method of identifying an epileptogenic zone of a subjects brain includes: receiving a plurality N of physiological brain signals that extend over a duration, each of the plurality N of physiological brain signals acquired from the subjects brain; calculating within a time window a state transition matrix based on at least a portion of each of the plurality N of physiological brain signals, wherein the state transition matrix is a linear time invariant model of a network of N nodes corresponding to the plurality N of physiological brain signals; calculating a minimum norm of a perturbation on the state transition matrix that causes the network to transition from a stable state to an unstable state; and assigning a fragility metric to each of the plurality N of physiological brain signals based on the minimum norm of the perturbation for that physiological brain signal.

Abstract: The perspiration state of a site of a living body including at least a part other than a local part of which the perspiration state is measured is accurately estimated. A perspiration data estimation device includes: a comparing section comparing local perspiration data acquired by a perspiration sensor with a first perspiration pattern indicating progression of the amount of perspiration on the local part over time; and a perspiration state estimating section estimating the amount of perspiration on the whole body on the basis of a result of the comparison at the comparing section and a second perspiration pattern indicating progression of the perspiration state of the whole body over time.

Abstract: Kits, diagnostic systems and methods are provided, which measure the distribution of colors of skin features by comparison to calibrated colors which are co-imaged with the skin feature. The colors on the calibration template (calibrator) are selected to represent the expected range of feature colors under various illumination and capturing conditions. The calibrator may also comprise features with different forms and size for calibrating geometric parameters of the skin features in the captured images. Measurements may be enhanced by monitoring over time changes in the distribution of colors, by measuring two and three dimensional geometrical parameters of the skin feature and by associating the data with medical diagnostic parameters. Thus, simple means for skin diagnosis and monitoring arc provided which simplify and improve current dermatologic diagnostic procedures.

Abstract: A method can be used for analyzing digital images of skin lesions. The images include pixels distributed over a lesion area. Sets of values including a first discrimination value indicative of a weighted average of the image pixels with weighing at the border of the lesion, a second discrimination value indicative of skewness and kurtosis of the distribution of the image pixels, a third discrimination value indicative of the ratio of symmetry and gray-level power of the distribution of the image pixels and calculated. A total additive score of the values in the sets of values is provided and compared with a total score threshold. The first, second and third discrimination values are compared with respective first, second and third discrimination threshold values. An output classification for the image analyzed is provided as a function of the results of the comparing.

Abstract: A handheld, conforming capacitive sensing apparatus configured to measure Sub-Epidermal Moisture (SEM) as a mean to detect and monitor the formation of pressure ulcers. The device incorporates an array of electrodes which are excited to measure and scan SEM in a programmable and multiplexed manner by a battery-less RF-powered chip. The scanning operation is initiated by an interrogator which excites a coil embedded in the apparatus and provides the needed energy burst to support the scanning/reading operation. Each electrode measures the equivalent sub-epidermal capacitance corresponding and representing the moisture content.

Abstract: Described is a method for detecting and displaying the movement of a temporomandibular joint which connects a lower jaw and an upper jaw by magnetic resonance imaging. A marker is secured to the lower jaw, a marker movement curve is generated using magnetic resonance imaging measurement data sets during a first measurement interval, during which the lower jaw is moved relative to the upper jaw, and a point which corresponds to a first position of the lower jaw relative to the upper jaw is ascertained on the movement curve. An image data set is generated during a second measurement interval, during which the temporomandibular joint is not moved, and a first model, which represents at least one part of the upper jaw and/or a temporal bone part that comprises the temporomandibular joint socket, and a second model, which represents at least one part of the lower jaw, are ascertained therefrom.

Abstract: Discloses are method and device determining threshold values for the volume and intensity of physical activity and the lowest levels of this activity that reduce risk factors in overweight persons who suffer from disorders of sugar and lipid metabolism. The method comprises of registering a person's daily physical activity, comparing it with the measured/predetermined threshold levels and informs the person, if the volume and/or intensity of the physical activity has been sufficient to prevent the effects of disease risk factors. Based on the disclosed methodology, overweight persons having disorders in sugar and lipid metabolism are able to perform physical activity maintaining health and reducing the risk factors. The invention described herein demonstrates a novel opportunity for overweight people having an abnormal blood sugar to use the low intensity physical activity to restrain risk factors related to cardiovascular diseases, diabetes and obesity.

Abstract: An eyelid position sensor system and/or an eye movement sensor system for an ophthalmic lens having an electronic system is described herein for recording data associated with sleep of the wearer. The eyelid position sensor system is part of an electronic system incorporated into the ophthalmic lens. The electronic system in at least one embodiment includes a system controller and a data manager. In at least one embodiment, the eyelid position sensor system is utilized to determine eyelid position and the eye movement sensor system is utilized to determine eye position for the system controller to determine if the wearer is awake, asleep, or in REM sleep.

Abstract: A monitoring non-invasive device for handling of sleep apnea, snoring and emergency situations operates for breathing assistance by means of transdermal stimulation of muscle groups including the pectoralis majoris, the serratus anterior, and the abdominal muscles. A wrist mounted version may alarm drivers or others requiring focus or concentration when they fall asleep and may alert a medical center. The invention may have a pulse oximeter on a person's wrist/finger to monitor their breathing while asleep, and in the event of a serious snoring or sleep apnea episode, activate the breathing assistance pulses.

Abstract: A biometric information measuring apparatus includes: a notification unit that notifies a subject holding breath to resume breathing when a specified time to hold breath is reached; and a measuring unit that measures an oxygen circulation time representing a time required for oxygen taken into a body of the subject by resumption of breathing by the subject to reach a predetermined site.

Abstract: A system and method for sleep disorder diagnosis and treatment are disclosed.

Abstract: The present invention generally relates to compositions comprising anesthesia-reversing agents which facilitate or increase the time of awakening or reverse the effects of general anesthesia-induced unconsciousness. In some embodiments, the anesthesia reversing agent can be selected from any or a combination of methylphenidate (MPH), amphetamine, modafinil, amantadine, caffeine, or analogues or derivatives thereof. In some embodiments, compositions comprising at least one or more anesthesia-reversing agents can be used to facilitate awakening from anesthesia without or decreasing occurrence of delirium, and can be used in methods to treat or prevent the symptoms associated with emergence delirium, as well as treat a subject oversedated with general an esthesia. The invention also relates to methods for administering these compositions comprising anesthesia-reversing agents to subjects and for use.

Abstract: A method for monitoring intoxication of a user, the method including: receiving a set of samples from a body region of a user; generating an intoxication metric based on the set of samples; and providing a notification to the user based on the intoxication metric. The method can additionally or alternatively include: modifying operation of the transdermal alcohol sensing device based on the intoxication metric; determining contextual data; maintaining a hydration level of the transdermal alcohol sensing device; and any other suitable processes. A system for monitoring intoxication of a user including a sensor and a housing. The system can additionally or alternatively include any or all of: an inlet, a fastener, an electronics subsystem, a user device, and/or any other suitable component.

Abstract: Systems, devices, and methods for post-surgical joint range of motion measurement, activity monitoring, as well as monitoring compliance with post-operative extremity elevation and cooling recommendations are provided. The system comprises sensor(s) to be attached adjacent a joint of the patient, with limb attachment element(s), applications running on a computing device of the patient and medical practitioner, and a cloud-based backend system.

Abstract: System for generating, emitting and interpreting a composite stream and associated method. The invention relates to a system making it possible to generate, transmit, interpret and exploit a composite data stream. The invention relates more precisely to a method for emitting a composite data stream advantageously through a wireless communication network, and a method for interpreting a composite data stream. Said methods are respectively implemented by the processing unit of an electronic object and by the processing unit of an electronic device.

Abstract: A probe holder for a brain function measurement device is provided with a holder portion including a probe attachment portion for attaching a measuring probe of the brain function measurement device, disposed on a subject's frontal region side, and deformable in accordance with the subject's head shape, a holder fixing portion disposed on the subject's occipital region side and formed in a loop shape such that a middle portion of the occipital region is fitted into the holder fixing portion, and a connecting unit connecting the holder portion on the frontal region side and the holder fixing portion on the occipital region side to each other.

Abstract: The present invention provides a system for monitoring a physiological parameter of players engaged in a sporting activity. The system includes a plurality of reporting units, a controller, and a signaling device. The reporting unit has an arrangement of sensing devices that measure the physiological parameter of an individual player and generate parameter data. The controller receives the parameter data transmitted from each reporting unit and then processes the parameter data to calculate a parameter result. When the parameter result exceeds a predetermined value, the controller communicates with a signaling device that provides an alert to sideline personnel to monitor the player(s) in question. The system also includes a remote storage device for holding historical data collected by the system which permits subsequent analysis.

Abstract: Described herein is a system and method for ergonomic analysis including a sensorized glove having an inner glove including a plurality of extensometer sensors for detecting relative movements between parts of a worker's hand, and an outer glove including a plurality of pressure sensors distributed over a palmar surface and for detecting pressure exerted in corresponding areas of said palmar surface; a wearable network of sensors being located in the network so that they can be associated to corresponding joints of the human body; a unit for generating a sequence of images of a worker task; and a processing unit for receiving data and/or signals from the sensorized glove, from the wearable sensor network, and/or from the unit, and configured for processing said data and/or signals to estimate ergonomic indicators and/or to obtain local information of effort and/or posture.

Abstract: A system and method for monitoring respiration of a user, comprising: a respiration sensing module including a sensor configured to detect a set of respiration signals of the user based upon movement resulting from the user's respiration; a supplementary sensing module comprising an accelerometer and configured to detect a set of supplemental signals from the user; an electronics subsystem comprising a power module configured to power the system and a signal processing module configured to condition the set of respiration signals and the set of supplemental signals; a housing configured to facilitate coupling of the respiration sensing module and the supplementary sensing module to the user; and a data link coupled to the electronics subsystem through the housing and configured to transmit data generated from the set of respiration signals and the set of supplemental signals, thereby facilitating monitoring of the user's respiration.

Abstract: Devices, apparatuses, and systems configured to assist in the location of an ABTT terminus and then to measure the temperature of the ABTT terminus.

Abstract: A method for detecting a wearable device's contact with a living body may be provided, including obtaining a decreasing rate of body temperature and a decreasing a rate of environmental temperature measured by a wearable device worn on a living body; and determining the wearable device's contact with the living body based on a comparison of the decreasing rate of body temperature and the decreasing rate of environmental temperature. A corresponding apparatus and computer program product for detecting a wearable device's contact with a living body may also be provided.

Abstract: One aspect includes a manufacturing method for a multielectrode system including providing several conductors, which are electrically conductive in their longitudinal direction; bundling the conductors at a proximal portion of the multielectrode system by means of a sheath surrounding the conductors to form a conductor bundle configured to be used as a lead of the multielectrode system; and providing several ring electrodes each surrounding one of the conductors at a distal portion of the multielectrode system and electrically connecting the ring electrodes and the conductors to form a multielectrode array of the multielectrode system. The multielectrode array is configured to be in a longitudinally extended or in a transversally expanded configuration.

Abstract: Pressure sensing guidewires and methods for making and using pressure sensing guidewires are disclosed. An example pressure sensing guidewire may include a tubular member having a proximal region and a housing region. An optical pressure sensor may be disposed within the housing region. The optical pressure sensor may include a sensor body and a deflectable membrane coupled to the sensor body. The deflectable membrane may include a polymer. An optical fiber may be coupled to the sensor body and may extend proximally therefrom. A pressure equalization channel is formed in the optical fiber, the sensor body, or both.

Abstract: A method includes obtaining monitoring data recorded by first and second devices, the first and second devices being attached to the subject at different first and second sties, respectively. The monitoring data comprises signals associated with at least one physiological parameter of the subject. The method also includes extracting one or more features of the signals recorded by the first and second devices during a transitionary period when the first and second devices simultaneously monitor the at least one physiological parameter of the subject. The method further includes generating at least one correlation parameter by analyzing the extracted features of the signals recorded by the first and second devices for at least a portion of the transitionary period, the at least one correlation parameter when applied to signals recorded by the second device at least partially compensating for relative changes in signals recorded by the first and second devices.

Abstract: A system for guiding and evaluating physical positioning, orientation and motion of the human body, comprising: a cloud computing-based subsystem including an artificial neural network and spatial position analyzer said cloud computing-based subsystem adapted for data storage, management and analysis; at least one motion sensing device wearable on the human body, said at least one motion sensing device adapted to detect changes in at least one of spatial position, orientation, and rate of motion; a mobile subsystem running an application program (app) that controls said at least one motion sensing device, said mobile subsystem adapted to capture activity data quantifying said changes in at least one of spatial position, orientation, and rate of motion, said mobile subsystem further adapted to transfer said activity data to said cloud computing-based subsystem, wherein said cloud computing-based subsystem processes, stores, and analyzes said activity data.

Abstract: The present disclosure provides systems and methods for predicting a disease state of a subject using ultrasound imaging and ancillary information to the ultrasound imaging. At least two quantitative measurements of a subject, including at least one measurement taken using ultrasound imaging, as part of quantified information can be identified. One of the quantitative measurements can be compared to a first predetermined standard, included as part of ancillary information to the quantified information, in order to identify a first initial value. Further, another of the quantitative measurements can be compared to a second predetermined standard, included as part of the ancillary information, in order to identify a second initial value. Subsequently, the quantitative information can be correlated with the ancillary information using the first initial value and the second initial value to determine a final value that is predictive of a disease state of the subject.

Abstract: A system including an electroencephalography (EEG) device configured to be positioned on a head of a user and process detected EEG signals. The system also includes a processor in communication with the EEG device, a memory accessible by the processor and instructions stored in the memory for execution by the processor to generate, based on a control instruction, a control data signal, for control of an operation of a controllable device configured to provide a premises related service in an area of a premises. In the training phase, execution of the instructions configures the processor to determine whether or not that the control operation of the control data signal is consistent with the detected EEG signals based on a trusted input from the user, and upon determination that the control operation is consistent with the detected EEG signals, store, in the memory, recognition data characterizing the detected EEG signals as a predetermined set of signals in association with the control instruction.

Abstract: The invention relates to a determination system (1) for determining a heart failure risk for a subject (4). The determination system is adapted to provide a cardiogram selected from a group consisting of a ballistocardiogram, a seismocardiogram and an impedance cardiogram of the subject, to detect at least one of a presence of a postextrasystolic potentiation (PESP) and a disturbed force-frequency relation (FFR) based on the provided cardiogram and to determine the heart failure risk based on this detection. By using the detection of the presence of the PESP and/or of a disturbed FFR, the heart failure risk can be reliably determined. In particular, it can be determined that the heart failure risk is relatively large, if a PESP is not present and/or if the FFR is disturbed.

Abstract: Systems and methods for home monitoring and detection of febrile neutropenia in a patient are provided. The system includes a photoplethysmographic sensor for sensing photoplethysmographic signals of the patient, and one or more blood borne parameter sensors for sensing parameters in the patient's blood. A febrile neutropenia monitoring application receives information sensed by the photoplethysmography sensor and the one or more blood borne parameter sensors and determines, based on the received information, the presence or deterioration of febrile neutropenia.

Abstract: The present disclosure discloses a health management mobile terminal, method, and server. The mobile terminal includes a display module, a microprocessor module, a communication module, and a medical module; the medical module is used to collect and monitor health information of a user; the microprocessor module is used to acquire health data of the user; the communication module is used to send the health data to a server in communication connection therewith, and receive a health analysis result acquired after the server analyzes the health data; the display module is used to perform detecting item selection, and display the health data and the health analysis result. In the present disclosure, the user can detect his/her own physical health situation at any time; in combination with the usage of smart cellphone, corresponding detection numerical values and graphs can be intuitively displayed through the display module.

Abstract: Methodologies and systems are provided for an operating location logging system for use in connection with a complex medical procedure. Example operating location logging systems include an image recording system configured to capture at least one image of a portion of at least one of a data recording object or a display of an instrument, and a console including at least one processing device. The at least one processing device is programmed to receive image data, representative of a plurality of images, that is transmitted using a data transmission component of the image recording system, and collect and/or compute medical data in connection with the complex medical procedure.