Abstract: A method of attaching a surgical suture inside of a pelvis includes moving an anchor deployment component relative to the anchor delivery component, pushing an anchor out of the anchor delivery component and into tissue inside of the pelvis, and engaging anchor with the tissue inside of the pelvis.

Abstract: A method of treating prolapse of a vagina includes supporting the vagina by implanting a sacrocolpopexy support and locating an exterior surface of the vagina between leg portions of a vaginal cuff section of the support, and securing a head section of the support to a ligament or a sacrum while isolating the head section from contact with tissue of the vagina.

Abstract: The present invention relates to an innovative biological prostheses, equipped with a drainage system, designed for all surgical applications where there is any risk of hematomas or seromas, which not only allows to minimize adverse events arising from its application, but allows also to improve the effectiveness of the functional reconstruction. The prosthesis of the present invention is a surgical prosthesis made of animal derived collagen having a peripheral outline and a drainage portion comprising a plurality of drainage holes which are located in one or more independent groups each of which has a regular body-centered polygon layout.

Abstract: A method for preparing a prosthetic valve and a delivery system for an implantation procedure. The method comprises (a) obtaining a tray, the tray containing the delivery system, the prosthetic valve coupled to the delivery system, and a valve cover in which the prosthetic valve is disposed. The tray comprises a storage cavity comprising an open end, a floor, and a peripheral side wall defining the depth of the cavity, wherein the prosthetic valve and the valve cover are disposed in the storage cavity; and a mounting surface that substantially immobilizes and maintains the valve cover and prosthetic valve within the storage cavity. The method further comprises (b) at least partially filing the storage cavity with a first hydrating fluid to completely immerse the prosthetic valve; and (c) removing the delivery device with the prosthetic valve from the tray, including disengaging the prosthetic valve from the mounting surface.

Abstract: A stent graft for placement in a vessel of a patient, the stent graft that has a tubular body of graft material, the tubular body having a proximal inflow end, a distal outflow end, a main lumen therethrough, a longitudinal access, and a sidewall from the first end to the second end. At least one stent is along the length of the tubular body. One or more shaped recesses are formed of a concave or recessed portion of graft material that extends into the lumen of the stent graft. A fenestration is in the recessed portion with a fenestration and an internal branch extends from the or each fenestration toward the proximal end of the tubular body of graft material. The internal branch may have a tubular portion and a funnel portion, wherein the tubular portion extends into the main lumen and the enlarged funnel portion is attached to sidewall and forms the at least one shaped recess.

Abstract: A device includes a first end portion, a second end portion, an intermediate portion between the first end portion and the second end portion, and a graft material coupled to at least the intermediate portion. The first end portion has a first end diameter. The second end portion has a second end diameter larger than the first end diameter. The intermediate portion tapers between the first end portion and the second end portion. A method of diverting fluid flow from a first passage to a second passage comprising deploying the device in a third passage between the first passage and the second passage, expanding the first end portion against sidewalls of the first passage, and expanding the second end portion against sidewalls of the second passage.

Abstract: A medical member of the present invention includes a knitted body knitted with a linear member formed in a linear shape, at least a part of the knitted body is constituted of an alloy containing titanium, tantalum, and tin, and the alloy is constituted of 15 at % to 27 at % of tantalum and 1 at % to 8 at % of tin, where the total is 100 at %, with remainder being titanium and unavoidable impurities. The knitted body is formed in a sheet shape by plain weaving, twilled weaving, plain dutch weaving, twilled dutch weaving, or stockinette stitch. Thus, there can be provided a medical member capable of dispersing a load applied to a treating site of a soft tissue.

Abstract: A device having an implantable body associated with at least two filaments or sutures and configured for use in soft tissue reconstructions is provided. One exemplary embodiment includes an implantable body, an adjustable filament loop for holding ligament grafts that is coupled to the body, and a shuttle suture removably coupled to the implantable body and configured for shuttling the body through at least a portion of a bone tunnel. The loop can be defined by a self-locking knot, and one or more loop-adjusting limbs can extend from the knot, with a portion of the limb(s) also extending into a hollow portion of the shuttle suture. In some embodiments having two adjustable limbs, an intermediate portion of each limb can be the portions disposed in respective hollow portions of the shuttle suture. Other configurations of devices and systems, as well as methods for performing ACL repairs, are also provided.

Abstract: In a method for providing a double loop stitch, a needle assembly having a first needle portion and a second needle portion that is removably connected to the first needle portion is provided. Opposing ends of a thread are connected to the needle portions, forming a loop that is placed around a sewing material. The needle assembly is inserted through the sewing material at an insertion point. The thread is then partially pulled through the sewing material at the insertion point such that a pair of loops of thread, separated by the insertion point, remain adjacent a first face of the sewing material. The needle portions are then separated and are passed around opposite sides of the sewing material from adjacent a second face back adjacent the first face. Each needle portion is then passed through one of the loops. The loops are then cinched and locked in place.

Abstract: A method for producing an implant, the method includes providing a hollow biocompatible shell to be implanted in an organ of a patient. At least two filling materials are injected at one or more locations in the shell, such that a mixture of at least two of the filling materials is configured to produce gas bubbles within a bulk of the mixture. The gas bubbles are formed in the injected filling materials by heating the shell containing the mixture of the injected filling materials.

Abstract: Accommodating intraocular lenses including an optic having an anterior element and a posterior element defining an optic fluid chamber, wherein the optic is aspheric across all powers throughout accommodation or disaccommodation. Intraocular lenses, optionally accommodating, where an optic portion is centered with a midline of a height of the peripheral portion, the height measured in the anterior to posterior direction.

Abstract: An intraocular lens whose application range is wider than that of the conventional single intraocular lens from the viewpoint of the characteristics at the time of bending of the support portion is made. An intraocular lens includes an optical portion having a predetermined refractive power; and a support portion configured to maintain a position of the optical portion in an eye. The support portion includes a main body formed of a flexible material and a shaft portion formed of an elastic material. At least a portion of the shaft portion is covered by the main body. An end of the shaft portion is provided away from the optical portion.

Abstract: An ophthalmic lens includes an optic comprising an anterior surface, a posterior surface, and an optical axis. At least one of the anterior surface and the posterior surface has a surface profile including a base curvature, a refractive region having the base curvature, and a diffractive region comprising a diffractive profile including a plurality of diffractive steps. At least a portion of the diffractive profile constitutes a combination of a base diffractive profile defining multiple foci for the ophthalmic lens and an achromatizing structure that reduces longitudinal chromatic aberrations.

Abstract: An ocular implant and a method for implanting such an ocular implant inside an eye includes an optical portion and at least two polymer haptics for fixation of the ocular implant to tissue inside an eye. At least one portion of the haptics contains a photoinitiating agent delivery component. A kit for implanting an ocular implant in an eye includes an ocular implant at least two polymer haptics; and additionally a photoinitiating agent for at least partially impregnating a first portion of the ocular element or a second portion of tissue in the eye; and, a light source for providing light of a wavelength adapted to excite the photoinitiating agent.

Abstract: Devices and methods for treating patients with functional tricuspid regurgitation (TR) who are unsuitable for surgery include an interoperative, adjustable-size coapting element on a catheter which may be implanted within the left or right side of the heart and extends upward into the vasculature and out of the body. The radial diameter of the coapting element can be modulated in tandem with electrocardiographic imaging to reduce valve regurgitation. One system has an elongated catheter and an expandable coapting element mounted to a distal end with an auxetic structure connected to opposite end caps. A tensioning mechanism controlled from a proximal end of the catheter is configured to pull apart the two end caps and thus elongate and radially expand the auxetic structure. Other forms of the coapting element are disclosed, as well as a kink-resistant catheter sheath having a triangular cross-section.

Abstract: Expandable docking stations for docking an expandable valve can include a valve seat, one or more sealing portions, and/or one or more retaining portions. The valve seat can be unexpandable or substantially unexpandable beyond a deployed size. The one or more sealing portions can be connected to the valve seat and extend radially outward of the valve seat. The one or more sealing portions can be constructed to expand outward of the valve seat and provide a seal over a range of sizes. The one or more retaining portions can be connected to the one or more sealing portions. The one or more retaining portions are configured to retain the docking station at a deployed position.

Abstract: An implant has a support structure (e.g., alloplastic) such as a stent or a scaffold, and a functional element (e.g., a heart valve) including or made of bacterial cellulose. At least a part of the support structure is embedded in the functional element or in an extension thereof so as to connect the functional element to the structural element via positive fit.

Abstract: A prosthetic valve comprises a self-expanding frame which includes a self-expanding atrial skirt that forms a flanged region, a self-expanding ventricular skirt, and a first self-expanding tab coupled with the ventricular skirt. A receptacle for receiving a valve leaflet is formed by the area bounded by an outer surface of the atrial skirt, an outer surface of the ventricular skirt, and an inner surface of the first tab. The receptacle has a window for receiving the valve leaflet that is defined by a gap between an edge of the flange and a tip of the first tab. The gap is maximized when the tip of the first tab is unconstrained and a base of the first tab is at least partially constrained. The gap is minimized when the tip of the first tab and its base are unconstrained.

Abstract: A heart valve prosthesis frame, the frame comprising a hollow tube shape for allowing blood to flow through; an upstream portion designed to expand to have at least one dimension wider than a native heart valve annulus; a downstream portion attached to the upstream portion, the downstream portion also designed to expand to have at least a portion with at least one dimension wider than the native heart valve annulus; wherein the downstream portion is shaped to have one side of the downstream portion of the hollow tube frame extend less from a center of the hollow tube than an opposite side of the hollow tube.

Abstract: To provide an artificial heart valve capable of aiding the functions of the mitral valve of a patient in a minimally invasive manner. An artificial heart valve 1 which includes a valve leaflet securing part 2 and valve leaflets (a first valve leaflet 5 and a second valve leaflet 7), and in which the valve leaflets are connected to the valve leaflet securing part 2 at the top portion of the artificial heart valve 1, the valve leaflets each have a region which narrows in width toward the bottom of the leaflet, and the artificial heart valve is an artificial mitral valve or an artificial tricuspid valve.

Abstract: Valve introducer systems and methods for implanting heart valve prostheses are disclosed, where a valve introducer includes an adjustable deployment mechanism comprising a deployment element and an implantation depth controlling element having a distal end and an adjustable length. The valve introducer also includes a tubular member having a distal end, configured to deliver a heart valve prosthesis, and a length extending from a fixed reference point. The implantation depth controlling element can comprise an inner and an outer cylinder, such as where the outer cylinder has interior threads, and the inner cylinder has exterior threads. The adjustable deployment element can include a depth gauge, wherein the depth gauge indicates the length the tubular member extends beyond a fixed reference point. In certain embodiments, the adjustable deployment element can also be configured to be secured to a cannula.

Abstract: In a particular embodiment, the present disclosure provides a prosthetic valve delivery assembly that includes a storage tube. A prosthetic valve having a frame is at least partially disposed within the storage tube. A nose cone is disposed about an elongated shaft. A stylet having at least a first bent portion extends through a lumen of the nose cone. The at least a first bent portion is disposed within the lumen of the nose cone and restricts axial movement of the elongated shaft relative to the prosthetic valve.

Abstract: A system for treating mitral regurgitation may include an outer sheath having a lumen extending to a distal end of the outer sheath, an intermediate sheath slidably disposed within the lumen of the outer sheath, the intermediate sheath having a lumen extending to a distal end of the intermediate sheath, and an inner sheath slidably disposed within the lumen of the intermediate sheath, wherein the inner sheath includes a first anchor disposed within a lumen of the inner sheath, the first anchor being configured to penetrate and secure to a first papillary muscle. The intermediate sheath may include a tissue grasping mechanism at the distal end of the intermediate sheath, the tissue grasping mechanism being configured to hold and stabilize the first papillary muscle for penetration and securement of the first anchor to the first papillary muscle.

Abstract: Devices and methods for providing localized pressure to a region of a patient's heart to improve heart functioning, including: (a) a jacket made of a flexible biocompatible material, the jacket having an open top end that is received around the heart and a bottom portion that is received around the apex of the heart; and (b) at least one inflatable bladder disposed on an interior surface of the jacket, the inflatable bladder having an inelastic outer surface positioned adjacent to the jacket and an elastic inner surface such that inflation of the bladder causes the bladder to deform substantially inwardly to exert localized pressure against a region of the heart.

Abstract: The present disclosure relates to improved plate and screw systems for use in fusion and other surgical procedures, which improve the ability to effectively affix adjacent bodies without gapping or experiencing loss of compression over time. The systems include plates having armatures configured to receive bushings, the bushings configured to pivot and rotate and thereby permit a greater degree of orientation of corresponding screws placed through the bushings. In embodiments, the bushings comprise anti-rotation elements which lock the bushings in a desired orientation. Methods for use of the components described herein are also disclosed.

Abstract: The invention is a prosthetic joint, for example, knee joint, including a first joint component which is preferably polyetheretherketone containing barium sulphate and a second joint component which is preferably a polyolefin.

Abstract: A joint prosthesis system is suitable for cementless fixation. The system includes a metal implant component that has a mounting surface for supporting an insert. The metal implant component includes a solid metal portion and a porous metal portion. The porous metal portion has surfaces with different characteristics, such as roughness, to improve bone fixation, ease removal of the implant component in a revision surgery, reduce soft tissue irritation, improve the strength of a sintered bond between the solid and porous metal portions, or reduce or eliminate the possibility of blood traveling through the porous metal portion into the joint space. A method of making the joint prosthesis is also disclosed. The invention may also be applied to discrete porous metal implant components, such as augment.

Abstract: An apparatus and methods are provided for a tapered implant for treating osteochondral defects. The tapered implant comprises a top portion that includes a shape that approximates an osteochondral surface to be replaced. A bottom portion of the tapered implant is configured to be implanted into a hole drilled in bone. A cylindrical sidewall of the tapered implant has a diameter that decreases from a first diameter of the top portion to a second diameter of the bottom portion. The tapered implant comprises any monophasic synthetic material suitable for implantation into bone, including any of silicone, bioglass, peek, polyethylene, titanium, and cobalt chrome.

Abstract: An artificial hip joint with a composite ball head includes an artificial acetabulum (1) and a composite ball head (2); wherein an internal surface of the artificial acetabulum (1) cooperates with an external surface of the composite ball head (2), and the composite ball head (2) can rotate within the artificial acetabulum (1); the internal surface of the artificial acetabulum (1) is directly in contact with the composite ball head (2) without a liner therebetween; the composite ball head (2) comprises a metal ball head (22) and a non-metallic shell (21) wrapped around an external surface of the metal ball head (22). For the composite ball head (2), the metal ball head (22) is wrapped with a non-metallic shell (21), which has large supporting force capability, has strong bearing capacity, effectively reduces the contact stress of the non-metallic shell (21), is stable and reliable.

Abstract: A femoral assembly includes a femoral component that includes condylar portions and an anterior flange portion. The condylar portions and anterior flange portion together define an outer side of the femoral component for articulating with a tibial prosthesis and an inner bone facing side opposite the outer side. The inner bone facing side defines five intersecting component inner surfaces that each extend from a lateral side of the femoral component to a medial side thereof. A femoral augment includes condylar portions and an anterior flange portion. The condylar portions and anterior flange portion together define an outer side of the femoral augment comprised of five intersecting augment outer surfaces and an inner side comprising no more than three intersecting augment inner surfaces. The augment outer surfaces correspond to the component inner surfaces of the femoral component. The augment inner surfaces correspond to resected surfaces of a distal femur.

Abstract: Method and set of surgical instruments for fitting a shoulder prosthesis, and the shoulder prosthesis. The proposed method seeks to interpose a bone graft between the previously prepared glenoid surface (G) of a scapula (S) of a patient's shoulder and the face of a glenoid prosthetic component opposite the articular surface. The set of instruments permit the bone graft to be taken from the upper epiphysis of the humerus (H), either in situ or ex vivo.

Abstract: System, including apparatus and methods, for ankle fusion using a device for separating a first bone and a second bone of an ankle region. In some embodiments, the device may comprise an expandable spacer including first and second bone-contacting surface regions facing away from one another and configured to be abutted with the first and second bones, respectively. A distance between the first and second bone-contacting surface regions may be adjustable to change the separation of the first and second bones. The first bone-contacting surface region may correspond to a portion of a sphere and may be configured to be disposed at least partially in a concavity formed surgically in the first bone. The expandable spacer offers improved control over the length of the lower limb and the orientation of the foot during ankle fusion surgery.

Abstract: The present invention relates to a stabilized ankle prosthesis configured for use in patients with compromised soft tissue in the ankle. The prosthesis of the present invention is a two-component design comprising a stabilizing lip configured to constrain movement in the general direction of compromised soft tissue.

Abstract: An implant is disclosed for the first metatarsophalangeal joint between the proximal phalange and the first metatarsal, the phalange moving in a sagittal plane perpendicular to a transverse plane. The implant includes a metatarsal component for securing against the distal end of the first metatarsal, the metatarsal component having an interfacing surface with a plurality of ridges and valleys. The implant further includes a phalangeal component for securing against the proximal end of the proximal phalange, the phalangeal component having an interfacing surface with a plurality of ridges and valleys, wherein the ridges of the interfacing surface of the metatarsal component are received by the valleys of the interfacing surface of the phalangeal component to provide for a full range of motion in the sagittal plane but impede motion in the transverse plane.

Abstract: A variable lordotic interbody spacer including a face plate, superior and inferior endplates coupled to the face plate via a hinge, an actuation frame between the endplates, and an actuation screw. The face plate includes actuation and stabilizer channels. Each of the endplates has endplate arms coupled by an endplate base, and includes actuation ramp recesses. The actuation frame includes frame arms coupled by a frame base in a generally U-shaped configuration, each actuation frame arm having a stabilizer feature passing through a corresponding stabilizer channel and having actuation ramp pins fitted to a corresponding ramp recesses. The actuation screw passes through the actuation channel, with a head retained at the front surface and a threaded end coupled to the actuation frame. When operated, the actuation screw moves the actuation frame between the superior endplate and the inferior endplate to adjust an angle therebetween.

Abstract: An oblique expanding fusion cage device including a body with a superior portion and an inferior portion. The superior portion and the inferior portion have a proximal end and a distal end. The fusion cage device also includes a pathway, an opening, and an expanding member. The pathway travels from the proximal end to the distal end of the device between the superior and inferior portions. The opening in the proximal end of the body enables access to the pathway. The expanding member may be re movably inserted into the opening and is moveable toward the distal end of the body, wherein the expanding member engages the superior portion and the inferior portion as the expanding member moves distally within the pathway.

Abstract: An adjustable spinal fusion intervertebral implant including upper and lower body portions each having proximal and distal surfaces at proximal and distal ends thereof. The implant can include a proximal wedge member disposed at the proximal ends of the respective ones of the upper and lower body portions, and a distal wedge member disposed at the distal ends of the respective ones of the upper and lower body portions. First and second linkages can connect the upper and lower body portions. Rotation of an actuator shaft can cause the distal and proximal wedge members to be drawn together such that longitudinal movement of the distal wedge member against the distal surfaces and the longitudinal movement of the proximal wedge member against the proximal surfaces causes separation of the upper and lower body portions.

Abstract: An intervertebral prosthesis for insertion between adjacent vertebrae includes upper and lower prosthesis plates locatable against respective vertebrae and having opposing, concavely curved recesses therein, and a core located between the plates. The core has opposed, convexly curved surfaces received in the recesses of the plates to allow the plates to slide in articulated manner over the core. The opposed surfaces of the core and the recesses of the plates have cooperating spherical curvatures. The recess of each plate surrounds a locating peg projecting centrally from the base of the recess and is bounded by an annular rim, such that the annular rims of the plates are arranged to contact one another at a predetermined limit of sliding movement of the plates over the core. The peg locates loosely in an opening located centrally in a curved surface of the core, whereby the plates can slide over the core in all directions while the peg holds the core captive.

Abstract: A unitary intervertebral device, having no moving components is provided for non-fusion articulation and fusion applications. The interbody articulating device allows for limited flexion and rotation between the implant and an adjacent vertebrae, helping to preserve or restore near-normal motion between adjacent vertebrae. Rotational motion is achieved through one or more protrusions incorporated into the spinal interbody device. In one articulating form, a first protrusion extends perpendicularly from one bearing surface of the interbody device to form a rotational protrusion, while at least a second protrusion extends from the opposite bearing surface of the interbody device to form a non-rotational protrusion. In another form, a single protrusion extends axially from one bearing surface of the interbody device to form a spike or anchoring, rotating protrusion, while the opposite bearing surface may be slightly rounded and/or comprising a bone-ingrowth promoting surface.

Abstract: The invention relates to a device intended to replace or partially replace one or more vertebral bodies or intervertebral discs in the cervical, thoracic or lumbar spine, and includes methods for its use and deployment. The invention may be used to restore biomechanical parameters correlating with improved patient outcomes and also involves a method for a more effective discectomy or corpectomy prior to graft deployment.

Abstract: The present invention involves a system and methods for assembling and implanting a vertebral body implant. The vertebral body implant includes, but is not necessarily limited to, an expandable core body and endplates that can be attached at both ends. Endplates of various shapes, sizes and angles are attachable to the expandable core so that a suitable vertebral body implant can be implanted between vertebrae.

Abstract: A surgical instrument (1) for knee balancing, comprising: a static tibial element (2) including a base and a tibial paddle (21); a femoral element (3) including a femoral paddle (31) and a femoral arm; a movable element (4) including a guide (40) movable in translation on the base according to a longitudinal axis (AL), wherein the femoral element is pivotally mounted on said movable element according to an anterior-posterior axis (AP), and a transverse arm; a system (5) for setting the mobility of said guide in order to provide a distraction function; a reversible blocking system coupled between the transverse arm and the femoral arm to pivotally immobilize the femoral element with respect to the movable element in a reversible manner in order to set the pivot angle of the femoral paddle with respect to the tibial paddle at different angle values.

Abstract: An implant including first and second end plates, each of which defines at least one anterior ramped surface and at least one posterior ramped surface. A posterior actuator is positioned between the first and second end plates and has guiding ramp surfaces which correspond with the posterior ramped surfaces. An anterior actuator is positioned between the first and second end plates and guiding ramp surfaces which correspond with the anterior ramped surfaces. An actuator assembly extends between the posterior actuator and the anterior actuator and is configured to selectively move the posterior actuator and the anterior actuator simultaneously, move posterior actuator independently of the anterior actuator, or move the anterior actuator independently of the posterior actuator.

Abstract: A spinal implant system includes at least one interbody implant having a first member including a tissue engaging surface and at least one mating dement. A second member includes a tissue engaging surface and at least one mating element. An intermediate member includes at least one mating element. An intra-operative surgical tool is connectable with at least one of the members to engage adjacent mating elements and fix the intermediate member with at least one of the first member and the second member. Implants, surgical instruments and methods are disclosed.

Abstract: A computer-assisted surgery system for outputting at least one of a leg length discrepancy and an offset between a preoperative leg condition and a post-implant rejointing leg condition comprises instruments. An inertial sensor unit is connected to one of the instrument, the inertial sensor unit producing readings representative of its orientation.

Abstract: Systems and methods for a running controller for a lower limb device including at least a powered knee joint are provided. The method includes collecting real-time sensor information for the lower limb device and configuring the lower limb device to a first state in a finite state model for an activity mode including the running mode. The method further includes, based on the sensor information, transitioning the lower limb device from a current state to a subsequent state in the finite state model for the detected mode when a pre-defined criteria for transitioning to the subsequent state is met, and repeating the transitioning until the activity mode changes. In the system and method, the finite state model includes at least one stance state and at least one swing state, where the at least one stance state includes at least one absorption state and at least one propulsion state.

Abstract: A lower limb prosthesis comprises an attachment section (10), a shin section (12), a foot section (14), a knee joint (16) pivotally connecting the attachment section (10) and the shin section (12), and an ankle joint (22) pivotally connecting the shin section (12) and the foot section (14). The knee joint includes a dynamically adjustable knee flexion control device (18) for damping knee flexion. The prosthesis further comprises a plurality of sensors (52, 53, 54, 85, 87) each arranged to generate sensor signals indicative of at least one respective kinetic or kinematic parameter of locomotion or of walking environment, and an electronic control system (100) coupled to the sensors (52, 53, 54, 85, 87) and to the knee flexion control device (18) in order dynamically and automatically to modify the flexion control setting of the knee joint (16) in response to signals from the sensors.

Abstract: A liner for an orthopedic or prosthetic device includes a core formed from a porous and compressible material, a first layer secured to the first side of the core and forming a first surface to the liner, and a second layer secured to the second side of the core and forming a second surface to the liner. The first and second layers may comprise different properties from one another and be formed from different materials including fabrics and polymeric materials. A polymeric film may be secured to the core or one of the layers to define at least part of a surface of the liner.

Abstract: Medical devices and method for making and using the same are disclosed. An example medical device may include implantable medical device for use along the biliary and/or pancreatic tract. The implantable medical device may include a tubular member having a first end configured to be disposed within the duodenum of a patient and a second end configured to be disposed adjacent to a pancreatic duct and/or bile duct. The tubular member may have a body including one or more wire filaments that are woven together. The tubular member may also have an outer surface with a longitudinal channel formed therein.

Abstract: Provided herein are implantable devices, such as vascular grafts and access port for hemodialysis, that include a microporous sheath layer having a corrugated outer surface, and use therefore for reducing the risk of infection or stenosis.