Patents Issued in January 9, 2020
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Publication number: 20200009287Abstract: A method and device are shown for use in casting for Total Contact Casting for offloading pressure in neuropathic and diabetic wounds or fractures of the appendages such as the human leg or foot. The outer casting material used can be comprised of traditional casting materials. A total foot protection pad underlies the traditional casting materials. It is a one piece moldable system that encompasses the total foot from the Achilles along the lateral and medial foot, covering the plantar surface, the malleoli and folds and extends over the dorsum. The one piece system has adhesive backing on a contact side to facilitate its application and/or forms a total foot protection pad beneath the outer hardened casting material.Type: ApplicationFiled: June 13, 2019Publication date: January 9, 2020Applicant: WoundKair Concepts, Inc.Inventors: Danny E. Anderson, Kimberly G. Anderson
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Publication number: 20200009288Abstract: An orthotic device for embracing and supporting a body part (e.g., articulation) of a human or animal. The orthotic device is a single sheet of moldable Polylactic Acid (PLA) material configured to maintain the body part in an optimal position for development and treatment. An orthotic system includes the PLA sheet and a protective layer in the form of a single moldable sheet of polyethylene foam (PEF). The PEF sheet is configured for placement between the PLA sheet and the body part.Type: ApplicationFiled: July 2, 2019Publication date: January 9, 2020Inventors: Charalampos Geremtzes, Dimitrios Moustakas
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Publication number: 20200009289Abstract: In one aspect, compositions for promoting hemostasis are provided. In some embodiments, the composition comprises a porous non-fibrous substrate impregnated with a hemostatic agent, wherein the porous non-fibrous substrate comprises a hydrophilic polyurethane foam. Methods of promoting hemostasis in a subject using such compositions, and methods of manufacturing such compositions, are also provided.Type: ApplicationFiled: March 2, 2018Publication date: January 9, 2020Applicant: LOMA LINDA UNIVERSITY HEALTHInventors: Mahmoud TORABINEJAD, Richard MASKIEWICZ
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Publication number: 20200009290Abstract: Provided is a liquid embolic agent composition capable of solving problems of conventional embolic agents, which can be used in a treatment of a vascular disease such as cerebral aneurysm. The problems are solved by a liquid embolic agent composition characterized in containing a hydrogel forming component having a calcium ion entrapping ability, and an anti-biodegradation component. The hydrogel forming component having a calcium ion entrapping ability is at least one kind of acidic polysaccharide selected from the group consisting of alginate, gellan gum, carrageenan, and carboxymethyl cellulose salt; and the anti-biodegradation component is at least one kind selected from the group consisting of hydroxypropyl methylcellulose, methylcellulose, polyvinyl alcohol, polyallylamine, poly-N-vinyl acetamide, and cellulose acetate.Type: ApplicationFiled: February 21, 2018Publication date: January 9, 2020Applicants: SHINSHU UNIVERSITYInventors: Ichiro YUKI, Kousaku OHKAWA, Takaomi NOMURA
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Publication number: 20200009291Abstract: The present invention provides novel methods for poling piezoelectric materials, e.g., collagen, which are carried out in the absence of liquid media and at a relatively low temperature. The present invention also provides electroactive scaffolds comprising poled collagen for promoting cell growth and differentiation.Type: ApplicationFiled: July 3, 2019Publication date: January 9, 2020Applicant: New Jersey Institute of TechnologyInventors: Treena Arinzeh, Michael Jaffe, Amir Hossein Rajabi
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Publication number: 20200009292Abstract: Methods and devices for the repair of articular tissue using collagen material are provided. Compositions of collagen material and related kits are also provided.Type: ApplicationFiled: September 4, 2019Publication date: January 9, 2020Applicant: The Children's Medical Center CorporationInventor: Martha M. MURRAY
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Publication number: 20200009293Abstract: Disclosed herein are elastic, bioresorbable encasements for medical implants, methods for making the same and uses thereof.Type: ApplicationFiled: September 27, 2017Publication date: January 9, 2020Inventors: Koon Kiat Teu, Jingnan Luo, Honglei Wang
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Publication number: 20200009294Abstract: Process for engineering instant nanoporous bio-artificial bone tissue composite is designed aiming the prevention of body immune reaction when integrated with host bone tissue and also reduces its period of integration. This nanoporous biocomposite is compounded by a number of ingredients. Hydroxylapatite (HA), or/and alpha- or beta-tricalcium phosphate (?- or ?-TCP). Polycaprolactone (PCL) or polylactic acid (PLA). Any gelatinable solution or gel, then water is added in relevant quantity for producing gel or injectable solution of this biocomposite. Any substance composed of any connective collagen tissue. Recombinant Human Vascular Endothelial Growth Factor. Any kind of acrylate when the hardening and final process of all this compound is acquired immediately by ultrasound treatment.Type: ApplicationFiled: January 29, 2018Publication date: January 9, 2020Inventors: Pali NAZIR, Rama NAZIR
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Publication number: 20200009295Abstract: Provided herein is a scaffold comprising a decellularized meniscus tissue, wherein the scaffold is covalently conjugated with heparin and a growth factor. Also provided herein is a method of repairing and/or treating a tissue injury in a subject in need thereof, comprising: providing a scaffold comprising a decellularized meniscus tissue; and repairing and/or treating the tissue injury by implanting the scaffold over the tear, wherein the scaffold is covalently conjugated with heparin and a growth factor.Type: ApplicationFiled: March 16, 2018Publication date: January 9, 2020Inventors: Martin Lotz, Kwang Il Lee
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Publication number: 20200009296Abstract: This invention relates, e.g., to a Myocyte-based Flow Assist Device (MFAD) for treating a subject in need of increased flow of a biological fluid, such as venous blood or lymph, comprising a sheath which comprises rhythmically contracting myocytes.Type: ApplicationFiled: July 15, 2019Publication date: January 9, 2020Applicant: The George Washington University a Congressionally Chartered Not-for-Profit CorporationInventor: Narine Sarvazyan
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Publication number: 20200009297Abstract: Implant comprising composite powder with microstructured particles, obtained by a process in which large particles are bonded to small particles, wherein the large particles have a mean particle diameter in the range from 10 ?m to 10 mm, the large particles comprise at least one polymer, the small particles are arranged on the surface of the large particles and/or are non-homogeneously spread within the large particles, the small particles comprise a calcium salt, the small particles have a mean particle size in the range from 0.01 ?m to 1.0 mm, wherein the particles of the composite powder have a mean particle size d50 in the range from 10 ?m to less than 200 ?m and the fine fraction of the composite powder is less than 50 vol %.Type: ApplicationFiled: August 11, 2017Publication date: January 9, 2020Inventors: Frank REINAUER, Siegmund LUGER, Marijan VUCAK
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Publication number: 20200009298Abstract: A hydrogel composite is provided. The hydrogel composite comprises a modified poloxamer having a first charge moiety and a peptide having a second charge moiety, wherein the first charge moiety and the second charge moiety are oppositely charged for ionic interaction between the modified poloxamer and the peptide, and wherein at least one of the modified poloxamer and the peptide comprises a crosslinkable moiety. In particular, the modified poloxamer is a pluronic monocarboxylate activated by dimethylaminopyridine and triethanolamine; the peptide is a gelatin methacrylate. A bioshaping method using the hydrogel composite is provided, as well as a three-dimensional network obtained by the bioshaping method.Type: ApplicationFiled: March 1, 2018Publication date: January 9, 2020Inventors: Ratima SUNTORNNOND, Jia AN, Chee Kai CHUA, Edgar Yong Sheng TAN, Wai Yee YEONG, Jie Kai ER
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Publication number: 20200009299Abstract: A material for use in a medical device includes a blend of a non-melt polymer such as Polyamideimide, a meltable carrier polymer such as Polyetherketoneketone and lubricants/rheology modifiers such that the final polymer material can be extruded, pelletized and used to injection mold components for the medical device. The ratios of the Polyamideimide, Polyetherketoneketone and the lubricants are selected to provide sufficient lubricity and glass transition temperature to the material to make it appropriate for use in high temperature applications and additive manufacturing processes.Type: ApplicationFiled: July 18, 2019Publication date: January 9, 2020Inventor: Jacqueline A. Anim
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Publication number: 20200009300Abstract: The disclosed medical device has high visibility on non-woven fabric having a color such as green, blue, or the like, excellent identifiability from other medical devices having a color such as green, blue, or the like, and high surface smoothness. The medical device comprises an elongated body and a resin layer for covering at least a proximal portion of the elongated body, in which the resin layer has a first layer which includes a first fluororesin, titanium oxide, and a dispersant, and a second layer which is formed on the first layer and includes a second fluororesin. The content of the titanium oxide is 30% by weight or more relative to the solid content of the first layer, and an acid value of the dispersant is 20 to 90 mg/KOH.Type: ApplicationFiled: September 19, 2019Publication date: January 9, 2020Applicant: TERUMO KABUSHIKI KAISHAInventor: Tomoya OIWA
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Publication number: 20200009301Abstract: An aspiration catheter is provided including a proximal section and a distal section extendable through the proximal section. A vacuum transfer tool may be coupled to a proximal end of the proximal section. The vacuum transfer tool may include a proximal transfer tube and a distal transfer tube, each having an aspiration port in communication with a vacuum source. The proximal transfer tube may be removably received within a proximal end of the distal transfer tube. The distal section of the catheter may be inserted into the proximal section through the proximal transfer tube. The proximal transfer tube may maintain a vacuum around the proximal end of the distal section of the catheter such that when the distal section is removed by decoupling the proximal and distal transfer tubes, the vacuum within the distal transfer tube and proximal section of the catheter is maintained, preventing the escape of any clots.Type: ApplicationFiled: July 5, 2019Publication date: January 9, 2020Inventor: Brandon Yee
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Publication number: 20200009302Abstract: A universal suction control device is disclosed that can be arranged in relation to surgical tubing to control the amount of air passing through the tubing. The suction control devices are arranged for easy, point-of-care control of suction while minimizing excessive noise pollution from suction during surgery. One suction control device comprises a mounting mechanism for mounting on surgical suction tubing. A first blocking portion is included for engaging the suctional tubing to block the passage of suction air through the tubing. A control surface is also included that is movable to control the engagement of said blocking portion with said surgical suction tubing to control the amount of air passing through said surgical suction tubing.Type: ApplicationFiled: March 11, 2019Publication date: January 9, 2020Inventor: CASEY PYLE
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Publication number: 20200009303Abstract: There are provided devices for applying negative pressure to a wound in an endoluminal surface of a patient to facilitate healing of the wound and methods for use of the devices. The device (69, 94, 134, 140, 156, 164) comprises a flexible porous element with an outer face defined between opposite proximal and distal ends of the porous element. A suction tube (30) for being connected to a suction source externally of the patient's body is in fluid communication with the porous element (14) to apply the negative pressure to the wound via the outer face of the porous element. In some embodiments, the porous element has a longtitudinal passageway (16) for passage of bodily substances of the patient along the lumen defining the endoluminal surface through the porous element. In such embodiments, the device may also have at least one absorbent element (70, 80) for absorbing the bodily substances and which is disposed forwardly or rearwardly of the porous element (14).Type: ApplicationFiled: July 19, 2019Publication date: January 9, 2020Inventor: Daniel Eduard Kleiner
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Publication number: 20200009304Abstract: Apparatus and methods for processing blood are disclosed in which one variation generally comprises a tube defining a channel and an access tube extending into the channel. An open cell matrix configured to entrap red blood cells may be positioned within at least a portion of the channel. Another variation generally comprises a cylindrical tube and a plunger slidably positioned within the channel. The plunger also has a funnel positioned upon the plunger and is movable therewith. Both the plunger and funnel define a fluid channel through and in communication with the cylindrical tube.Type: ApplicationFiled: June 24, 2019Publication date: January 9, 2020Applicant: Hanuman Pelican, Inc.Inventors: Randy DORIAN, Michael D. LEACH, Richard W. STORRS, Scott R. KING
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Publication number: 20200009305Abstract: The present disclosure relates to a saccular cavopulmonary assist device, including a shell, an inflow tube (6) and an outflow tube (4), wherein a blood storage cavity (A) and a power cavity (B) are arranged in the shell, and the power cavity (B) is used for providing contraction and relaxation power for the blood storage cavity (A); the inflow tube (6) is arranged at a position corresponding to the power cavity (B) on the shell, an outer end is used for communicating with the vena cava, and an inner end communicates with the blood storage cavity (A) after passing through the power cavity (B); the outflow tube (4) is arranged at a position corresponding to the blood storage cavity (A) on the shell, an outer end is used for communicating with the pulmonary artery, and an inner end communicates with the blood storage cavity (A).Type: ApplicationFiled: March 29, 2018Publication date: January 9, 2020Inventors: Haiyun YUAN, Jian ZHUANG, Jimei CHEN, Chengbin ZHOU, Huanlei HUANG, Shusheng WEN
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Publication number: 20200009306Abstract: Disclosed is an assembly for fitting/removing a heart pump in a sleeve secured in an opening in a ventricular wall, the assembly including a guide element with a distal end, a proximal end, and a lumen extending between, and opening at, the distal and proximal ends, the heart pump having a pump body. With this pump body including an assembly element, the assembly includes a gripping unit which can slide in the lumen, the gripping unit having at its free end an assembly part which is complementary with the assembly element, which part is configured to cooperate with the assembly element, and to join this free end to the pump body, in order to permit the gripping and displacement of the heart pump.Type: ApplicationFiled: November 20, 2017Publication date: January 9, 2020Inventors: Stéphane GARRIGUE, Arnaud MASCARELL
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Publication number: 20200009307Abstract: A blood pump system is implantable in a patient for ventricular support. A pumping chamber has an inlet for receiving blood from a ventricle of the patient. An impeller is received in the pumping chamber. A motor is coupled to the impeller for driving rotation of the impeller. A motor controller is provided for tracking systolic and diastolic phases of a cardiac cycle of the patient and supplying a variable voltage signal to the motor in a variable speed mode to produce a variable impeller speed linked to the cardiac cycle. The impeller speed comprises a ramping up to an elevated speed during the diastolic phase in order to reduce a load on the ventricle at the beginning of the systolic phase.Type: ApplicationFiled: September 20, 2019Publication date: January 9, 2020Inventors: Alexander Medvedev, Masamichi Yanai
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Publication number: 20200009308Abstract: A medicament preparation system, according to an embodiment, includes a water purification module and a medicament proportioning module. The system is configured to allow convenient and safe use in a home environment or a critical care environment as well as others affording safety, reliability, and a compact form factor.Type: ApplicationFiled: September 19, 2019Publication date: January 9, 2020Applicant: NxStage Medical, Inc.Inventors: Goetz FRIEDERICHS, William K. WEIGEL, Dennis M. TREU, Jeffrey H. BURBANK, James M. BRUGGER, Keith David J. WHEELER, Scott W. NEWELL
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Publication number: 20200009309Abstract: A cell processing system includes at least one processor connectable to a source container filled with a biological fluid, the processor including a spinning membrane configured to receive and separate target cells from the biological fluid, the target cells exiting at a first outlet, first and second containers selectively connected to the first outlet; and a magnet. The system also includes a controller configured to operate the spinning membrane to receive biological fluid and to direct the target cells to the first container, to pause to permit magnetic particles to be associated with the target cells in the first container, to operate the spinning membrane to receive the contents of the first container with the magnet applied to the target cells associated with the magnetic particles, to remove or deactivate the magnet, and to transfer the target cells to the second container.Type: ApplicationFiled: September 19, 2019Publication date: January 9, 2020Inventors: Christopher J. Wegener, Bret M. Olson, Alaina Schlinker, Steven Binninger, Avnie A. Kadakia, Kyle Thompson, Kyle Wolok, Melanie Hamilton
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Publication number: 20200009310Abstract: Dialysis machines and methods for heating dialysate before delivery into a dialysis patient (e.g., peritoneal dialysis machines) may comprise a dialysis machine including one or more internal cooling components configured to expel heated air from the dialysis machine. A receptacle may be configured to receive one or more containers of dialysate. The one or more containers of dialysate may be positionable relative to the expelled heated air of the dialysis machine. The expelled heated air may be flowable around the one or more containers of dialysate to increase a temperature of the dialysate. The receptacle may include a stand for positioning the dialysis machine such that the expelled heated air is directed around the one or more containers of dialysate.Type: ApplicationFiled: July 6, 2018Publication date: January 9, 2020Inventors: Bert D. Egley, Daniel H. Schmidt
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Publication number: 20200009311Abstract: A medical fluid delivery system comprises: (i) a medical fluid delivery machine including a pneumatic manifold having pump and valve actuation areas and a pumping gasket overlaying the pump and valve actuation areas, sources of positive and negative pneumatic pressure, plural pneumatic valves located between the pneumatic sources and the pump and valve actuation areas, and a control unit in operable communication with the plural pneumatic valves; and (ii) a disposable cassette including a fluid pump chamber that aligns with the pump actuation area when the disposable cassette is mated with the pneumatic manifold, the disposable cassette including sheeting overlaying the fluid pump chamber, wherein the control unit is configured to operate the pneumatic valves to perform a conditioning routine that moves the pumping gasket and the cassette sheeting while mated in an attempt to remove small air pockets from between the pumping gasket and the cassette sheeting.Type: ApplicationFiled: July 2, 2019Publication date: January 9, 2020Inventor: Matthew David Wilcox
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Publication number: 20200009312Abstract: A system for concentrating cells, wherein a syringe comprises a lumen and an axial end comprising a port and a radial end closed to liquid flow. A plunger divides the axial and radial ends, and the syringe is configured to hold a cellular suspension. A filter disposed at the radial end is configured to maintain sterility of the syringe. A cap comprises a vent disposed at the radial end. The plunger is configured to be actuated towards the axial end by air pressure being applied into the radial end and the plunger is configured to be actuated towards the radial end by a vacuum being applied into the radial end.Type: ApplicationFiled: June 17, 2019Publication date: January 9, 2020Inventors: Kyungyoon Min, Christopher J. Wegener, Alexander Dodge
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Publication number: 20200009313Abstract: A system and method to irrigate a user's auditory canal. A fluid can be dispensed from a reservoir through a fluid path and out through openings of a delivery element into the auditory canal. A pump may be used to facilitate the process of dispensing the fluid. The fluid can be delivered to the user's auditory canal for a predetermined period of time. Such a time period may be user selectable. The discharge from the irrigation is removed from the user's auditory canal via a discharge port located on the delivery element. The discharge exits the delivery element and proceeds to a discharge reservoir via a discharge path. A vacuum may be used to generate a negative pressure to facilitate the removal of the discharge from the auditory canal.Type: ApplicationFiled: September 20, 2019Publication date: January 9, 2020Applicant: SafKan, Inc.Inventor: Aadil DIWAN
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Publication number: 20200009314Abstract: The disclosure refers to an encapsulation device for use with a drug delivery device comprising a housing containing a syringe, wherein the encapsulation device comprises at least: a body, a cap, wherein the body has an inner surface forming a cavity configured to retain an end of an outer surface of the housing of the drug delivery device and the cap has an inner surface forming a cavity configured to retain the opposite end of the drug delivery device and, in an assembled state of the encapsulation device, the cap and the body are releasably interconnected with each other to encapsulate the drug delivery device.Type: ApplicationFiled: February 26, 2018Publication date: January 9, 2020Inventor: Michael Helmer
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Publication number: 20200009315Abstract: An automatic fluid injection device comprising: a base body (1) for coming into contact with an injection zone; a support assembly (2) for supporting an actuator mechanism (5, 6, 7) that is controlled by power supply means (11); at least one fluid reservoir (3), each containing an injection piston (35), arranged in said base body (1); a needle assembly (100) comprising an insertion actuator (8), needle movement means (9, 9?), a priming needle (101) for associating with each reservoir (3) and for penetrating into said reservoir (3) before moving its piston (35), and an injection needle (102) for penetrating into the injection zone and for injecting the contents of said reservoir(s) (3) into said injection zone, said device including at least one actuator button (200) for priming, inserting the injection needle into the injection zone, administering fluid, and then retracting the injection needle.Type: ApplicationFiled: February 16, 2018Publication date: January 9, 2020Applicant: APTAR FRANCE SASInventors: Guillaume BROUET, Sam REEVES
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Publication number: 20200009316Abstract: An automatic injector for delivering a pharmaceutical substance from a reservoir of a cartridge, the cartridge interconnected to a needle at its distal end and mechanically coupled to a plunger driver at its proximal end, the injector comprising a connecting feature on the cartridge a contact surface for contacting an injection site a frame connected to the contact surface, the frame having an interference element with a distal stop, the interference element sized to slidably link to the connecting feature and allow the cartridge to slide up to the distal stop, a snap element allowing the interference element to receive the connection feature, but inhibiting disconnection of the cartridge; the frame further comprising a driver mount, for fixedly containing a plunger driver, the driver for driving a plunger to empty the reservoir of the cartridge through the needle to inject fluid from the reservoir into the injection subject.Type: ApplicationFiled: September 16, 2019Publication date: January 9, 2020Inventors: Oz CABIRI, Ran HEZKIAHU
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Publication number: 20200009317Abstract: The subject invention provides a drug delivery device for injecting medicament which includes a tubular reservoir; a stopper slidably disposed in the reservoir; a spring for moving the stopper in the reservoir; at least one needle, the needle having a distal end for insertion into a patient, and a lumen extending proximally from the distal end, the lumen being in direct or indirect communication with the reservoir; a needle driver for displacing the needle; and an actuator. Activation of the actuator causes the spring to move the stopper and the needle driver to displace the needle. The needle moves relative to, and separately from, the reservoir with the needle being displaced. Advantageously, with the subject invention, a drug delivery device is provided wherein a needle is moved, relative to the reservoir, in being displaced for injection. This permits control of the needle displacement separate from the reservoir.Type: ApplicationFiled: September 17, 2019Publication date: January 9, 2020Applicant: Becton, Dickinson and CompanyInventors: Richard A. Cronenberg, Lionel Vedrine, Paul Alchas
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Publication number: 20200009318Abstract: An infusion device. The infusion device includes a top portion comprising an introduction needle, and a bottom portion comprising a cannula, the top portion removably attached to the bottom portion, wherein the introduction needle is used to insert the cannula, and wherein after insertion, the top portion is removed from the bottom portion.Type: ApplicationFiled: September 16, 2019Publication date: January 9, 2020Inventors: Dean Kamen, Kevin l. Grant
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Publication number: 20200009319Abstract: Portable or ambulatory infusion devices and systems capable of remotely updating an ambulatory fluid delivery device include safety protocols that verify the status of the ambulatory fluid delivery device before and after a field update of software. Methods of accomplishing the same field update of software are also described.Type: ApplicationFiled: September 19, 2019Publication date: January 9, 2020Inventor: Don Ludolph
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Publication number: 20200009320Abstract: Portable or ambulatory infusion devices and systems capable of remotely updating an ambulatory fluid delivery device include safety protocols that verify the status of the ambulatory fluid delivery device before and after a field update of software. Methods of accomplishing the same field update of software are also described.Type: ApplicationFiled: September 19, 2019Publication date: January 9, 2020Inventor: Don Ludolph
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Publication number: 20200009321Abstract: A wearable medical device comprising an annular housing configured to attach to a wrist of a patient. The wearable medical device having a first receptacle attached to the annular housing for receiving a first portion of a tube of an intravenous delivery system. The wearable medical device comprising a flow regulator attached to the annular housing and in contact with the first portion of the tube, where the flow regulator is configured to modify a geometric characteristic of the first portion of the tube. The wearable medical device further comprising a wireless transmitter for communicating with a user console.Type: ApplicationFiled: July 5, 2018Publication date: January 9, 2020Inventors: Jing Du, Tzu-Chen Chao, Ci-Wei Lan, Xiang Yu Yang, Chao Zhang, Xin Fang Hao
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Publication number: 20200009322Abstract: The present disclosure relates to an information transmitter having an electronics circuit, said electronics circuit has a transmitter; an antenna operably connected to said transmitter. Memory storage elements are also included having unique identification data with at least one activation element capable of activating said electronics circuit to transmit said unique identification data to external receivers. The present disclosure also relates to a medicament delivery device utilizing the information transmitter.Type: ApplicationFiled: May 31, 2019Publication date: January 9, 2020Inventors: Markus Bauss, Per Lindstedt, Rasmus Renstad, Nikolaj Hautaviita, Daniel Säll
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Publication number: 20200009323Abstract: An auto-injector is provided which includes a housing with a syringe slidably received therein. The syringe has a barrel with a piston movable therein and a needle extending therefrom. The piston is releasably secured to one end of a plunger which is slidably secured within a body in the housing and is operable through a bias provided by a motive source. In use, the plunger moves under the bias from a loaded condition to a discharged condition to move the syringe so that the needle extends from a tip at an injection end of the housing and to slide the piston within the barrel to expel the contents of the syringe. The plunger is held in the loaded condition against the bias by a detent extending from the body and which can be selectively released by operation of an actuator when pressure is applied to the tip.Type: ApplicationFiled: March 12, 2018Publication date: January 9, 2020Inventors: Gokul Arjunan Nair, Michael Levin, Sudesh Sivarasu
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Publication number: 20200009324Abstract: Systems and methods for triggering a drug injection device are disclosed. One disclosed system for injecting a substance into a patient includes: a chamber comprising a propellant; a light source mechanically coupled to the chamber, wherein energy from the light source ignites the propellant; and a power source electrically coupled to the light source via a control circuit, wherein the control circuit applies power to activate the light source.Type: ApplicationFiled: June 24, 2019Publication date: January 9, 2020Applicant: Verily Life Sciences LLCInventors: Daniel Barrows, Grant Smith
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Publication number: 20200009325Abstract: The present invention relates to a monitoring device (10) arranged to be operably connected to a medicament delivery device (12), said medicament delivery device (12) comprising a manually operated movable dose activation element (20), said monitoring device (10) comprising an electronic circuit (42), said electronic circuit (42) comprising an optical sensor (68), wherein said optical sensor (68) is positioned in relation to said dose activation element (20) so as to detect a manual operation of said dose activation element (20) from an initial position; said electronics circuit further comprising a vibration sensor (70), wherein said vibration sensor (70) is positioned in relation to said medicament delivery device so as to detect specific vibration spectra produced by the medicament delivery device when said dose activating element (20) is operated, wherein said electronic circuit (42) comprises computing elements capable of correlating the information from the optical sensor (68) with the information fromType: ApplicationFiled: February 27, 2018Publication date: January 9, 2020Inventor: William Cirillo
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Publication number: 20200009326Abstract: A female syringe of a syringe kit includes a female syringe barrel including a cylindrical portion into which a nozzle of a male syringe is insertable, a hollow cylindrical packing arranged in the cylindrical portion, and a cap detachably attached to the cylindrical portion. When the cap is detached from the cylindrical portion, the packing remains in the cylindrical portion, a distal end opening is opened, and the nozzle of the male syringe is fitted in a liquid-tight manner to an inner side of the packing.Type: ApplicationFiled: September 20, 2019Publication date: January 9, 2020Applicant: TERUMO KABUSHIKI KAISHAInventor: Hitoshi OKIHARA
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Publication number: 20200009327Abstract: Disclosed is a Huber needle assembly that may include an upper body connected to a lower body, the assembly being structured to retain a needle for insertion/extraction of the needle into/from an insertion site. The upper body can statically retain the needle while the lower body may slidably receive the needle. The lower body can further include a catch that engages a tip of the needle and/or misaligns the tip of the needle with a needle aperture of the lower body to place the assembly in a safety-lock position, preventing rebound, needle-stick injury, and/or any type of exposure of the needle tip to an environment outside of the lower body. The assembly can further bias the needle in a direction so as to prevent re-emergence of the needle tip after being withdrawn into the lower body.Type: ApplicationFiled: September 20, 2019Publication date: January 9, 2020Inventors: Kurt Shimer, Matthew Gunn, Raymond Bizup
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Publication number: 20200009328Abstract: A syringe assembly includes: a syringe including: a puncture needle having a needle tip, and a barrel holding the puncture needle; a hollow cylindrical grip fitted on an outer peripheral portion of the barrel; and a protective device including a hollow cylindrical cover member that is axially displaceable relative to the barrel, the protective device being configured such that the cover member covers at least part of the puncture needle in an initial state, the cover member is displaceable in a proximal direction relative to the barrel by being pressed against an object to be punctured when the puncture needle is inserted into the object to be punctured, and the cover member is configured to cover the needle tip after insertion of the puncture needle into the object to be punctured.Type: ApplicationFiled: September 16, 2019Publication date: January 9, 2020Applicant: TERUMO KABUSHIKI KAISHAInventors: Fumiya MATSUMOTO, Masafumi TAKEMOTO
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Publication number: 20200009329Abstract: Method for coating a glass syringe body for a hypodermic pre-filled glass syringe, wherein at least one emulsion and/or one solution containing at least one layer-forming substance is applied to at least one inner surface of the hypodermic pre-filled glass syringe, which defines an axial direction, wherein at least a partial surface of the inner surface in a syringe cone of the pre-filled glass syringe is subsequently exposed to a plasma, wherein a negative pressure source is arranged in relation to the syringe cone in the axial direction opposite the atmospheric-pressure plasma source, wherein a negative pressure of less than atmospheric pressure is provided by means of the negative pressure source.Type: ApplicationFiled: July 8, 2019Publication date: January 9, 2020Inventors: Christian Daniel, Lukas Baier
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Publication number: 20200009330Abstract: The present invention generally provides a device for inserting needles and alleviating the discomfort associated with needle insertion. In certain embodiments, the device is suited for injecting butterfly needles and particularly butterfly needles that are attached to infusion tubing. The patient or caregiver loads a butterfly needle with tubing attached into the base of the drive plunger. The needle with tubing attached is retracted into the housing of the device by retracting the inner plunger. Once retracted, the device is activated and ready to administer a needle into the tissue of a patient. The device is then placed on the location of the skin where injection is desired. The surface that contacts the skin may be textured and may include a contact switch that causes the device to vibrate when slight pressure is applied through contact with the skin.Type: ApplicationFiled: August 26, 2019Publication date: January 9, 2020Inventors: Andrew I. SEALFON, Christopher Erol Ogut
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Publication number: 20200009331Abstract: A system for priming an infusion pump is disclosed. The system includes a priming cap including a septum and configured to matably connect with a male part comprising a needle and attached to a length of tubing for fluid, wherein when matably connected with the male part, the priming cap occludes the tubing.Type: ApplicationFiled: September 16, 2019Publication date: January 9, 2020Inventors: Dean Kamen, Marc A. Mandro, Kevin A. Durand, Gregory R. Lanier, Kevin L. Grant, Larry B. Gray, Brian D. Tracey
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Publication number: 20200009332Abstract: A nebulizer has an aperture plate, a mounting, an actuator, and an aperture plate drive circuit (2-4). A controller measures an electrical drive parameter at each of a plurality of measuring points, each measuring point having a drive frequency; and based on the values of the parameter at the measuring points makes a determination of optimum drive frequency and also an end-of-dose prediction. The controller performs a short scan at regular sub-second intervals at which drive current is measured at two measuring points with different drive frequencies. According to drive parameter measurements at these points the controller determines if a full scan sweeping across a larger number of measuring points should be performed. The full scan provides the optimum drive frequency for the device and also an end of dose indication.Type: ApplicationFiled: September 16, 2019Publication date: January 9, 2020Applicant: Stamford Devices LimitedInventors: Joseph GREHAN, Niall SMITH
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Publication number: 20200009333Abstract: A nebulizer for nebulizing a fluid from a cartridge and a cartridge for such a nebulizer is proposed. The cartridge comprises a container containing the fluid to be nebulized and is fluidically connected to the nebulizer by inserting a connecting element of the nebulizer for conveying the fluid out of the container. The cartridge is preferably adapted to sealingly receive the connecting element and can optionally comprise a membrane or sealing wall which seals the cartridge initially and is piercable or breakable by the connecting element upon insertion. The cartridge can further comprise an at least partially flexible and/or bendable tube for conveying the fluid out of the container. The tube is preferably wettable with the fluid and/or comprises an at least partially hydrophilic and/or polar surface. Further, the tube can at least partially be shaped as a helix.Type: ApplicationFiled: December 21, 2017Publication date: January 9, 2020Applicant: Boehringer lngelheim International GmbHInventors: Stephen Terence DUNNE, Joachim Carl Herbert EICHER, Herbert GRAESSL, Andree JUNG, Gilbert WUTTKE
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Publication number: 20200009334Abstract: The present invention relates to a preparation for inhalation use in form of dry powder comprising particles of ambroxol and/or hydrochlorides thereof, and at least a pharmaceutically acceptable excipient and/or dispersant wherein at least 85% of said particles has a geometrical diameter from 3 to 5 ?m. The present invention further relates to the methods for preparing such composition and uses thereof. The present invention thanks to the very fine particles of dry powder, as above defined, constitutes a composition for inhalation use with optimum performances which, combined with inhaler action, reaches and acts directly on the bronchi or on the damaged respiratory tract. The local action and the quick absorption of the drug guarantee good features of bioavailability. The decrease in dosing Ambroxol with respect to the other existing oral or injectable formulations allows to reach quickly, locally and safely, the therapeutic target.Type: ApplicationFiled: July 2, 2019Publication date: January 9, 2020Inventors: Qi WU, Huaxin WU
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Publication number: 20200009335Abstract: An inhaler includes a mouthpiece cover, a pressure sensor, a first indicator and a second indicator. The first indicator may be configured to indicate based on a state of the cover, and the second indicator may be configured to indicate based on an output of the pressure sensor. For example, when the mouthpiece cover opens, the first indicator may illuminate and a dose of medication may be transferred from a reservoir to a dosing cup. The second indicator may illuminate if an amount of inhaled medication reaches a predetermined threshold for successful inhalation.Type: ApplicationFiled: September 16, 2019Publication date: January 9, 2020Applicant: Norton (Waterford) LimitedInventors: Enrique Calderon Oliveras, Daniel Buck, Frederic Scott Fleming, Douglas E. Weitzel
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Publication number: 20200009336Abstract: The present disclosure relates to a heating inhaler and a controlling method thereof. The method includes: the sensing element detecting a suction action, and if the sensing element detects the suction action within a first predetermined time period, the control circuit board controlling the power source to supply power to the atomizer for a second predetermined time period then stop supplying, wherein the indicating element displays a first state within the second predetermined time period until the power source stops supplying power to the atomizer, then the indicating element displays a second state. If the sensing element detects no suction action within the first predetermined time period, the control circuit board controlling the power source to stop supplying the electric power to the atomizer, and the indicating element displaying the second state.Type: ApplicationFiled: June 21, 2019Publication date: January 9, 2020Applicant: SHENZHEN SMOORE TECHNOLOGY LIMITEDInventor: Qiaofang FENG