Patents Issued in January 16, 2020
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Publication number: 20200015701Abstract: Multiple circuits in a computing device can share one or more conductive elements. The use of the conductive element can vary by circuit, such as an antenna radiator for a radio frequency (RF) circuit or an electrode for an electrocardiography (ECG) circuit. The circuitry sharing a conductive element can utilize signals obtained over different frequency ranges. Those ranges can be used to select decoupling circuitry, or elements, that can enable the respective circuits to obtain signals over a respective frequency range, excluding signals over one or more other frequency ranges corresponding to other circuitry sharing the circuit. Such an approach allows for concurrent independent operation of the circuitry sharing a conductive element.Type: ApplicationFiled: June 28, 2019Publication date: January 16, 2020Inventors: Yonghua WEI, Faton TEFIKU, Kevin LI, Man-Chi LIU, Lindsey Michelle SUNDEN, Peter W. RICHARDS, Dennis Jacob McCRAY, Christos Kinezos IOANNOU, Kyung Nim NOH
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Publication number: 20200015702Abstract: A system for landmarking a patient during a medical procedure, such as Magnetic Resonance (MR) Imaging, is disclosed. A video display monitor displays images from a video camera positioned in a location relative to an isocenter of the medical device, and a patient's position is adjusted to align a feature of interest on the patient with a reference marker displayed on the monitor. A landmark may be declared on the feature of interest such that the system can move the patient to place the landmarked feature of interest substantially at the isocenter of the medical device.Type: ApplicationFiled: July 9, 2019Publication date: January 16, 2020Applicants: Children's Hospital Medical Center, NeoView, Inc.Inventors: Charles Lucian DUMOULIN, Steven Gerard LEE, Christoph Lewis GILLUM
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Publication number: 20200015703Abstract: A catheter has single axis sensors mounted directly along a portion of the catheter whose position/location is of interest. The magnetic based, single axis sensors are on a linear or nonlinear single axis sensor (SAS) assembly. The catheter includes a catheter body and a distal 2D or 3D configuration provided by a support member on which at least one, if not at least three single axis sensors, are mounted serially along a length of the support member. The magnetic-based sensor assembly may include at least one coil member wrapped on the support member, wherein the coil member is connected via a joint region to a respective cable member adapted to transmit a signal providing location information from the coil member to a mapping and localization system. The joint region provides strain relief adaptations to the at least one coil member and the respective cable member from detaching.Type: ApplicationFiled: September 9, 2019Publication date: January 16, 2020Inventors: Maribeth Esguerra Wilczynski, Jennifer Maffre, Thanh Nguyen
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Publication number: 20200015704Abstract: A guidewire insertion tool configured to measure a length of an anatomic region. The tool can include a housing, a light chamber, and a track at least partially extending through the light chamber. The track is adapted to guide a guidewire as it is advanced through the insertion tool. The tool can also include an optical sensor assembly in optical communication with the light chamber. The optical sensor assembly can include one or more light sources, an optical sensor, and a magnifier. The one or more light sources can be adapted to direct light toward a portion of the guidewire within the track, and the optical sensor can be adapted to receive reflected light from the portion of the guidewire within the tract. A processing unit can analyze data from the optical sensor assembly to determine the length of the anatomic region and output the measurement to a display.Type: ApplicationFiled: March 18, 2019Publication date: January 16, 2020Inventors: Suman K. Mulumudi, Mahesh S. Mulumudi
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Publication number: 20200015705Abstract: Systems and methods for automatically triggering wireless power and data exchange between an external reader and an implanted sensor. The implanted sensor may measure the strength of an electrodynamic field received wirelessly from the reader and convey field strength data based on the measured strength of the received electrodynamic field to the reader. If the field strength data indicates that the strength of an electrodynamic field received by the sensor is sufficient for the implanted sensor to perform an analyte measurement, the reader may convey an analyte measurement command to the sensor, which may execute the analyte measurement command and convey measurement information back to the reader. The systems and methods may trigger the analyte measurement as the reader transiently passes within sufficient range/proximity to the implant (or vice versa).Type: ApplicationFiled: September 17, 2019Publication date: January 16, 2020Applicant: Senseonics, IncorporatedInventors: Arthur E. Colvin, JR., Andrew DeHennis
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Publication number: 20200015706Abstract: Disclosed herein are systems and methods for producing an illumination pattern in a gas tube of a facially-fitting device, which is used in conjunction with a capnograph. The illumination pattern is determined by at least one illumination parameter, derived at least from measured CO2 data, such that the illumination pattern is indicative of at least one breath-related/physiological parameter and/or one or more of the respiratory/physiological conditions determined/assessed based at least on the CO2 data.Type: ApplicationFiled: July 11, 2018Publication date: January 16, 2020Inventors: Michael KERTSER, Tzvika LEFKOVITS
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Publication number: 20200015707Abstract: A breath analyte device includes a breath volume in fluid communication with a sampling volume. The device also includes a sampling sensor configured to generate a breath signal that varies in response to changes in gas pressure (e.g., sound waves) in the breath volume and an analyte sensor configured to generate an analyte signal that varies in response to a concentration of a target analyte present in the sampling volume. A control unit is configured to determine a time at which to measure the concentration of the target analyte in the sampling volume based on the breath signal and measure the concentration of the target analyte in the sampling volume based on the analyte signal at the determined time. The device may also include a pump configured to motivate gas from the breath volume into the sampling volume prior to measuring the concentration of the target analyte.Type: ApplicationFiled: June 27, 2019Publication date: January 16, 2020Inventors: Timothy V. Ratto, Matthew V. Ratto
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Publication number: 20200015708Abstract: A method and apparatus is provided for the analysis of gaseous compounds, especially for determining the concentration of a gas or gases in a gas mixture by microwave spectroscopy. Microwave radiation is generated at one or more frequencies the gas is most responsive to, transmitted by antenna, passed through the gas under test, received by antenna, and the absorption and/or reflection of the microwave radiation is measured by means such as digitization and analysis using the FFT spectrum versus energy response generated, the response subsequently used to calculate the gas concentration.Type: ApplicationFiled: September 23, 2019Publication date: January 16, 2020Applicant: NOKOMIS, INC.Inventors: JAMES ROBERT UPLINGER, II, ROBERT M. NICHOL, WALTER JOHN KELLER
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Publication number: 20200015709Abstract: A method for detecting cough sounds from a sound wave of a subject includes applying features extracted from the sound wave to at least two electronic pattern classifiers including a first classifier trained to detect an explosive phase of a cough and a second classifier trained to detect one or more post-explosive phases of the cough sound. The features extracted from the sound wave are applied to the second classifier after the first classifier has classified features of the sound wave as an explosive phase of a cough sound.Type: ApplicationFiled: February 1, 2018Publication date: January 16, 2020Inventors: Vesa Tuomas Kristian Peltonen, Anthony James Keating, Nicholas Kim Partridge
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Publication number: 20200015710Abstract: A device and method for measuring the amount of knee extension loss, hyperextension, or extensor length associated with arthritis, trauma, surgery or other medical conditions. This device and method includes measuring the difference in heel heights of a patient while patient is lying prone on a table with their legs, at the level of their knee caps, off the table. This device and method also measures extensor length in a patient's knee joint, by assessing heel height difference while a patient is lying prone on a table with a prone knee bend. This device and its methods provide accurate distance measurements that correlate to knee straightness and flexibility; these distinguishing metrics are unattainable by a standard “disc” goniometer. In addition, this device permits convenient measuring of a knee's mobility for two unique perspectives, namely in prone with legs straight or with a knee bent.Type: ApplicationFiled: July 11, 2018Publication date: January 16, 2020Inventor: Kevin Cummings
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Publication number: 20200015711Abstract: Embodiments of the present disclosure relate to systems and methods of locating a patent within a facility. In one example, the system includes a beacon and a sensor. The beacon is positioned in a location of the facility. The beacon includes an infrared emitter and a processor. The processor is in communication with the infrared emitter. The processor is configured to instruct the infrared emitter to periodically emit an infrared emission. The processor modulates the infrared emission with a unique identification of the beacon that corresponds to the location of the beacon. The sensor is worn by the sensor wearer. The sensor includes an infrared receiver and a processor. The processor is in communication with the infrared received. The infrared receiver is configured to demodulate the received infrared emission to identify the unique identification of the beacon.Type: ApplicationFiled: September 25, 2019Publication date: January 16, 2020Inventors: Satish Movva, Srinaag V. Samudrala, Hassan Waqar Azeem Chaudhary, Joshua David Paladeni, Gregory B. Zobel
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Publication number: 20200015712Abstract: A method includes: receiving, by a first processing device, first data from a first inertial sensor positioned on a user, generated when the user is in a body position; analyzing the first data to identify a posture of the body position; receiving, by the first processing device, second data from a second inertial sensor positioned on the user, wherein the second data are generated when the user performs a fundamental movement; analyzing the second data to identify a distinguishing characteristic of the fundamental movement; determining whether a correlation exists between the posture of the body position and the distinguishing characteristic of the fundamental movement; and, if a correlation between the posture of the body position and the distinguishing characteristic of the fundamental movement is determined to exist, displaying an indication of the correlation to the user on a second processing device.Type: ApplicationFiled: July 13, 2018Publication date: January 16, 2020Inventor: Maury Hayashida
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Publication number: 20200015713Abstract: A system and method are described herein for a sensor device which biomechanically detects in real-time a user's movement state and posture and then provides real-time feedback to the user based on the user's real-time posture. The feedback is provided through immediate sensory feedback through the sensor device (e.g., a sound or vibration) as well as through an avatar within an associated application with which the sensor device communicates. The sensor device detects the user's movement state and posture by capturing data from a tri-axial accelerometer in the sensor device. Streamed data from the accelerometer is normalized to correct for sensor errors as well as variations in sensor placement and orientation. Normalization is based on accelerometer data collected while the user is wearing the device and performing specific actions.Type: ApplicationFiled: April 26, 2019Publication date: January 16, 2020Inventors: Andrew Robert Chang, Andreas Martin Hauenstein, Monisha Perkash, C. Charles Wang
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Publication number: 20200015714Abstract: A method includes receiving during a first time interval associated with a path of motion of a dynamic body, image data associated with a plurality of images of the dynamic body. The plurality of images include an indication of a position of a first marker coupled to a garment at a first location, and a position of a second marker coupled to the garment at a second location. The garment is coupled to the dynamic body. During a second time interval, an image from the plurality of images is automatically identified that includes a position of the first marker that is substantially the same as a position of a first localization element relative to the dynamic body and a position of the second marker that is substantially the same as a position of the second localization element relative to the dynamic body.Type: ApplicationFiled: September 27, 2019Publication date: January 16, 2020Applicant: Veran Medical Technologies, Inc.Inventors: Jerome R. Edwards, Troy L. Holsing, Torsten M. Lyon, Evan Austill, JR., Christopher B. Lee
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Publication number: 20200015715Abstract: A system for detecting and recording head orientations of a person includes: a first sensor device capable of providing sensor data regarding a head orientation of a person in a three-dimensional space; a data acquisition system configured for storing and outputting the sensor data from the first sensor device; and a processor configured for processing the sensor data from the data acquisition system, outputting a first signal representing the head orientation, and generating an image for presentation by a graphical display; wherein the image comprises: a first reference indicator; an orientation indicator, wherein a position of the orientation indicator in the image is determined based on the first signal from the processor, and a feedback indicator when a first condition is met.Type: ApplicationFiled: September 22, 2019Publication date: January 16, 2020Applicant: Natus Medical IncorporatedInventors: Hamish MACDOUGALL, Robert NYGREN, Wendy CRUMLEY-WELSH
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Publication number: 20200015716Abstract: The present disclosure relates to noninvasive methods, devices, and systems for measuring various blood constituents or analytes, such as glucose. In an embodiment, a light source comprises LEDs and super-luminescent LEDs. The light source emits light at at least wavelengths of about 1610 nm, about 1640 nm, and about 1665 nm. In an embodiment, the detector comprises a plurality of photodetectors arranged in a special geometry comprising one of a substantially linear substantially equal spaced geometry, a substantially linear substantially non-equal spaced geometry, and a substantially grid geometry.Type: ApplicationFiled: June 21, 2019Publication date: January 16, 2020Inventors: Jeroen Poeze, Marcelo Lamego, Sean Merritt, Cristiano Dalvi, Hung Vo, Johannes Bruinsma, Ferdyan Lesmana, Massi Joe E. Kiani
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Publication number: 20200015717Abstract: A method of analysis using mass spectrometry or ion mobility spectrometry that includes producing ions from a sample in a proximity of the sample, transferring the produced ions from the sample to a distance with a flexible or re-configurable ion guide, the flexible or re-configurable ion guide being connected to RF voltages, and separating the produced ions with a mass to charge or mobility analyzer located at the distance to provide spectrometric results; and detecting the separated ions with at least one detector.Type: ApplicationFiled: July 11, 2019Publication date: January 16, 2020Inventor: Mazdak Taghioskoui
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Publication number: 20200015718Abstract: Provided are transdermal microneedle-based devices for sensing the presence and concentration of analytes such as electrolytes, biomarkers, drugs, and proteins in interstitial fluid. Also provided are methods and systems to transmit the data obtained by wired or wireless connection to a receiver and to relay the data to the user or a clinician.Type: ApplicationFiled: June 14, 2019Publication date: January 16, 2020Inventors: Jose Antonio Maiz-Aguinaga, Lennart Olsson
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Publication number: 20200015719Abstract: The present embodiments provide systems and methods for, among others, tracking sensor insertion locations in a continuous analyte monitoring system. Data gathered from sensor sessions can be used in different ways, such as providing a user with a suggested rotation of insertion locations, correlating data from a given sensor session with sensor accuracy and/or sensor session length, and providing a user with a suggested next insertion location based upon past sensor accuracy and/or sensor session length at that location.Type: ApplicationFiled: June 13, 2019Publication date: January 16, 2020Inventors: Katherine Yerre Koehler, Leif N. Bowman, Rian Draeger, Laura Dunn, Eli Reihman
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Publication number: 20200015720Abstract: A continuous glucose monitoring system and method has an inserter assembly for inserting a sensor through the skin and into subcutaneous tissue where an inserter housing with the sensor remains on the skin after insertion, a sensor housing cover attachable to the sensor housing after insertion where the sensor housing cover has an electronic module and a battery, and an electronic device equipped with wireless communication for communicating with the electronic module of the sensor housing cover assembly, the electronic device configured for receiving input signals from the sensor, converting the input signals to analyte date, displaying the analyte data on a user interface of the electronic device, storing the data for recall, and creating and/or sending reports of the data.Type: ApplicationFiled: December 22, 2016Publication date: January 16, 2020Applicant: Sanvita Medical, LLCInventors: Thomas H. Peterson, Handani Winarta, Anthony Florindi
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Publication number: 20200015721Abstract: A system and method are provided to detect a possible respiratory blockage by using personalized carbon dioxide (CO2) concentration change patterns without concerning its absolute values. The personalized change patterns can intelligently learn new change pattern to increase its accuracy. Advanced pattern recognition is used to detect abnormal CO2 concentration change pattern by comparing to personalized patterns, and allowing the system to trigger alarm to alert a caregiver or a guardian.Type: ApplicationFiled: September 20, 2019Publication date: January 16, 2020Inventors: Lawrence Cheng, Charles T. Cheng
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Publication number: 20200015722Abstract: A passive electronic resonator can be configured with a resonant frequency that changes according to changes in the permittivity of a surrounding environment. A wireless device can then wirelessly measure the formation of a biological deposition such as thrombosis or biofilm on the resonator by wirelessly measuring changes in the resonant frequency reflected in corresponding changes to a driving point impedance for the resonator.Type: ApplicationFiled: March 6, 2018Publication date: January 16, 2020Inventors: Kaustav A. Gopinathan, Eduardo A. Maury, Dylan V. Neel
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Publication number: 20200015723Abstract: A pulse oximetry device is provided that fixates generally around a user's wrist. The device may include one or more mechanical features that fix the device at, for example, a distal end of a wearer's ulna bone. The device may include one or more projections formed from a suitable material (e.g., elastomer such as silicon) that cause the device to fit snugly against the wearer's wrist and remain in place even when the wearer is moving, thus reducing motion artifacts in signals detected by the device. The device may include one or more mechanical features or fins that reduce ambient or stray light in the measurement area. The device may include one or more detectors, and one or more light sources, each having a different axis resulting from the manner in which each is angled toward a virtual center point of the distal end of a wearer's ulna bone.Type: ApplicationFiled: December 15, 2017Publication date: January 16, 2020Applicant: Oxitone Medical Ltd.Inventors: LEON EISEN, Uzi Ben-Zion, Koby Refael Gil, Ofer Harpak, Avi Shaham
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Publication number: 20200015724Abstract: A non-invasive monitor for measuring regional saturation of oxygen includes a sensor unit containing a printed circuit board on which a light emitting unit and a light receiving unit are mounted; a main body unit; a sensor holder for holding the sensor unit while the light emitting unit and the light receiving unit are disposed in an aperture portion; a sensor pressing board; a connecting unit for electrically connecting the sensor unit and the main body unit; and a headband. The light emitting unit and the light receiving unit are disposed such that a light emitting surface and a light receiving surface face the forehead-side, and a part or the whole of the forehead-side surface of the sensor unit is on the same surface as the forehead-side surface of the sensor holder or protrudes from the forehead-side surface of the sensor holder toward the forehead-side.Type: ApplicationFiled: July 12, 2019Publication date: January 16, 2020Inventors: Eiichi MATSUI, Mitsuo MATSUI, Yasuo NAKAJIMA
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Publication number: 20200015725Abstract: A device uses push-initiated force to collect, meter, filter and store a blood sample. In one implementation, the push-initiated force may be provided in a cassette-type housing that also collects, meters, filters and/or stores the blood sample.Type: ApplicationFiled: May 24, 2019Publication date: January 16, 2020Inventors: Brandon T. Johnson, Keith Kopitzke, Catherine Fink
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Publication number: 20200015726Abstract: The disclosed embodiments relate to a system that uses a video game to improve spatial and/or temporal information-processing capabilities of a user. During operation, the system enables the user to play the video game. During execution of the video game, the system first measures spatial and/or temporal information-processing capabilities of the user during the course of playing the video game. Next, the system uses the measured spatial and/or temporal information-processing capabilities to control a spatial placement and/or a temporal presentation rate of target items that the user is required to respond to during subsequent game play to stimulate enhancement of the user's spatial and/or temporal information-processing capabilities.Type: ApplicationFiled: September 4, 2019Publication date: January 16, 2020Applicant: The Regents of the University of CaliforniaInventor: Anthony J. Simon
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Publication number: 20200015727Abstract: A computer-implemented method, system, and computer program product where a processor(s) displays, at a first location in an interface of a computing device, image(s) comprising a fixation point. The processor(s) obtains, from an eye tracking device, a first indication that a user whose eye movement is being tracked has at least one eye focused on the fixation point. The processor(s) renders, at a second location in the interface, a visual stimulus to stimulate a predefined location in a retina of the at least one eye. The processor(s) obtains, from the eye tracking device, a second indication that a user does not have the at least one eye focused on the fixation point. The processor(s) identifies a third location, a focal point of the user. The processor(s) reorients the image(s) such that the fixation point is at the third location and the stimulus is moved relative to the fixation point.Type: ApplicationFiled: July 16, 2019Publication date: January 16, 2020Inventor: Andrew Maskery
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Publication number: 20200015728Abstract: The present disclosure relates to a system (60) for monitoring a state of well-being of an individual, the system (60) comprising a remotely operating sensing unit (30) comprising at least one image sensor (32, 34) arranged to remotely monitor a skin portion of a user, a close-up sensing unit (56) provided at a hand-held personal care appliance (40), the close-up sensing unit (56) being arranged to monitor a physiological signal of the user, wherein the monitoring of the physiological signal is temporally aligned with the remote monitoring of the skin portion of the user, and a control unit (70) arranged to process first sensor data provided by the remotely operating sensing unit (30) and second sensor data provided by the close-up sensing unit (56), wherein the control unit (70) is arranged to process, based on the processed first sensor data and second sensor data, at least one well-being parameter, and wherein the control unit (70) is arranged to provide, based on the at least one processed parameter, wellType: ApplicationFiled: February 27, 2018Publication date: January 16, 2020Applicant: Koninklijke Philips N.V.Inventors: Maria Estrella MENA BENITO, Ihor Olehovych KIRENKO
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Publication number: 20200015729Abstract: The invention is a method for determining a stress level of an individual, depending on a physiological parameter of the individual, the method comprising: a) measuring a physiological-parameter value in various calibration periods during a calibration time period; b) defining a range of variation in the physiological-parameter values measured in the various calibration periods; c) depending on the range of variation, establishing a membership function defining a stress level of the individual depending on the physiological-parameter value, the stress level defined by the membership function being able to vary between: a rest level, corresponding to a rest state of the individual; a stressed level, corresponding to a stressed state of the individual; and at least one intermediate level, comprised between the rest level and the stressed level; d) following c), measuring a physiological-parameter value during a measurement period, and determining the stress level of the individual by applying the membershType: ApplicationFiled: July 12, 2019Publication date: January 16, 2020Applicants: Commissariat A L'Energie Atomique et aux Energies Alternatives, Universite Grenoble AlpesInventors: Gael VILA, Christelle GODIN, Aurelie CAMPAGNE, Sylvie CHARBONNIER
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Publication number: 20200015730Abstract: In order to objectively grasp a stress state of a user and to prevent postpartum depression, biological gas information is acquired via a network, where the biological gas information indicates a concentration of dimethyl adipate of the user and is obtained by a sensor that detects dimethyl adipate released from a skin surface of the user. From a memory storing information including an upper limit of a normal range of the concentration of dimethyl adipate per unit period, the information indicating the upper limit of the normal range is read out. When a frequency in the unit period with which the concentration of dimethyl adipate of the user exceeds the upper limit of the normal range is determined to have an increasing tendency based on the biological gas information obtained during a pregnancy period of the user, the information related to stress of the user is output to an information terminal of the user.Type: ApplicationFiled: September 20, 2019Publication date: January 16, 2020Inventors: YUKARI NISHIYAMA, MASAHIKO TSUKUDA, YASUAKI OKUMURA
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Publication number: 20200015731Abstract: To objectively grasp a stress state of a user and to prevent a mental disorder of the user, the following steps are performed: acquiring, via a network, biogas information at multiple timings and time information corresponding to each of the multiple timings, wherein the biogas information represents a concentration of tetradecane of a user acquired by a sensor that detects tetradecane discharged from a skin surface of the user; obtaining reference information representing an upper limit of a normal range of the concentration of tetradecane per unit period of time, using a memory storing the reference information representing the upper limit of the normal range; determining a stress time period during which a concentration of the tetradecane of the user is more than the upper limit of the normal range, based on the acquired biological gas information; and outputting time period information indicating the determined stress time period to an information terminal of the user, to display the stress time period inType: ApplicationFiled: September 26, 2019Publication date: January 16, 2020Inventors: YUKARI NISHIYAMA, MASAHIKO TSUKUDA, YASUAKI OKUMURA
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Publication number: 20200015732Abstract: In order to objectively grasp a stress state of a user and to prevent postpartum depression, biological gas information is acquired via a network, where the biological gas information indicates a concentration of tetradecane of the user and is obtained by a sensor that detects tetradecane released from a skin surface of the user. From a memory storing information including an upper limit of a normal range of the concentration of tetradecane per unit period, the information indicating the upper limit of the normal range is read out. When a frequency in the unit period with which the concentration of tetradecane of the user exceeds the upper limit of the normal range is determined to have an increasing tendency based on the biological gas information obtained during a pregnancy period of the user, the information related to stress of the user is output to an information terminal of the user.Type: ApplicationFiled: September 26, 2019Publication date: January 16, 2020Inventors: YUKARI NISHIYAMA, MASAHIKO TSUKUDA, YASUAKI OKUMURA
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Publication number: 20200015733Abstract: The present system is directed in various embodiments to devices, systems and methods for detection, evaluation and/or monitoring olfactory dysfunction by measuring and determining the patient's olfactory detection threshold for the left and the right nostril. In some cases, the present invention relates to devices, systems and methods for detecting an asymmetric differential in a patient's relative olfactory detection and/or identification threshold (left vs right nostril) which, when present, may be used as a device to detect, diagnose and/or monitor olfactory deterioration resulting from Alzheimer's disease, and/or the efficacy of treatment regimens therefor over time. Alternatively, general olfactory dysfunction may be evaluated and/or monitored without regard to the individual nostril's performance.Type: ApplicationFiled: July 10, 2018Publication date: January 16, 2020Inventor: Gregory B. Mills
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Publication number: 20200015734Abstract: The purpose of this embodiment is to describe a “one stop shop” for staging prostate cancer and a novel application of supervised target detection algorithms to spatially registered multiparametric MRI images in order to non-invasively detect, locate, and score prostate cancer at the voxel level and measure the tumor volume and assign color to the spatially registered MRI to highlight and display tumors, and detect metastases (specifically in the seminal vesicle). To test the approach advanced by the embodiment, a retrospective study analyzes MRI from 26 patients that had also undergone robotic prostatectomy. Whole-mount sections were stained for histopathologic evaluation and matched to the MRI. The stained sections were independently reviewed by pathologists. All slices of various types of MRI were spatially registered and stitched together. Signatures or image-based biomarkers from registered multiparametric MRI training sets were extracted.Type: ApplicationFiled: December 5, 2017Publication date: January 16, 2020Inventor: Rulon Mayer
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Publication number: 20200015735Abstract: The present disclosure provides methods and apparatus for evaluating the flow of blood in damaged or healing tissue. The present disclosure also provides methods of identifying a patient at the onset of risk of pressure ulcer or at risk of the onset of pressure ulcer, and treating the patient with anatomy-specific clinical intervention selected based on perfusion or blood oxygenation values, or a combination thereof. The present disclosure also provides methods of stratifying groups of patients based on risk of wound development and methods of reducing incidence of tissue damage in a care facility. The present disclosure also provides methods to analyze trends of perfusion or oxygenation measurements to detect tissue damage before it is visible, and methods to compare bisymmetric perfusion values to identify damaged tissue.Type: ApplicationFiled: July 15, 2019Publication date: January 16, 2020Applicant: Bruin Biometrics, LLCInventors: Martin F. BURNS, Graham O. ROSS
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Publication number: 20200015736Abstract: A therapy device may include one or more sensors for measuring metrics. The measured metrics may include at least one of heart rate, range of motion, muscular activity, blood pressure, temperature, sweat or respiration of a patient that correspond to an exercise. The therapy device may include a communication component to provide the measurements from the one or more sensors to a computing device. The communication component may receive feedback from the computing device based on a comparison of the measured metrics from the one or more sensors to a set of target metrics associated with the exercise. The therapy device may include one or more lights to provide visual feedback associated with the exercise based on the received feedback from the computing device.Type: ApplicationFiled: July 5, 2018Publication date: January 16, 2020Inventors: Meshal Alhathal, Maryam Alkhaldi
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Publication number: 20200015737Abstract: A system is configured to diagnose sleep comprising an apparatus configured to be attached to a patient; the apparatus comprises: i) an optical sensor configured to measure a blood volume pulse of the patient; and ii) a wireless communication interface configured to wirelessly transmit the measured blood volume pulse. The system further comprises means for performing: i) obtaining the wirelessly transmitted measured blood volume pulse; and ii) deriving from the blood volume pulse the peripheral arterial tone; iii) determining occurrences of sleep events from changes in the peripheral arterial tone.Type: ApplicationFiled: July 10, 2019Publication date: January 16, 2020Inventors: Bart VAN PEE, Frederik MASSIE, Duarte MINGOT DE ALMEIDA MENDES DE ALMEIDA
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Publication number: 20200015738Abstract: A blood sugar regulation system including: a blood sugar sensor; an insulin injection device; and a processing and control unit predicting the future evolution of the blood sugar based on a physiological model and accordingly controlling the insulin injection device, wherein the processing and control unit is capable of: a) implementing a calibration of the model by taking into account a history of the measured blood sugar; b) at the end of the calibration step, determining whether the model is satisfactory or not based on at least one numerical indicator representative of the error between the blood sugar estimated based on the model and the real blood sugar measured by the sensor; and c) if the quality of the model is not satisfactory, controlling the insulin injection device without taking into account the predictions made from the model.Type: ApplicationFiled: September 19, 2017Publication date: January 16, 2020Applicant: Commissariat à I'Énergie Atomique et aux Énergies AlternativesInventor: Eléonore Doron
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Publication number: 20200015739Abstract: Medical devices and related patient management systems and event detection methods are provided. An exemplary method of detecting events pertaining to operation of a medical device, such as an infusion device, involves obtaining measurements indicative of a condition in a body of a patient, determining statistics for an analysis interval based on the measurements, and determining an event probability associated with the analysis interval based on historical event data associated with the patient. An event detection model associated with the patient is obtained and applied to the statistics and the event probability to identify occurrence of the event using the event detection model, and in response, an indication of the event associated with the analysis interval is provided, for example, by tagging or marking data in a database, displaying graphical indicia of the event, or the like.Type: ApplicationFiled: September 23, 2019Publication date: January 16, 2020Inventors: Sinu Bessy Abraham, Chantal M. McMahon, Pratik Agrawal, Boyi Jiang, Yuxiang Zhong, Michael P. Stone, Huzefa F. Neemuchwala
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Publication number: 20200015740Abstract: Systems and methods for monitoring an animal include receiving a plurality of biological parameters of the animal from a plurality of biological sensors, receiving location parameters of the animal from at least one location sensor, receiving weather parameters corresponding to ambient weather conditions proximate the animal from at least one ambient weather sensor, and comparing at least one of the parameters generated by the sensors with data representing at least one signature corresponding to the animal to determine if there is an irregular parameter. In response to an irregular reading/parameter being identified, then determining if the identified irregular parameter is related to a health condition of the animal and if the identified irregular parameter is not related to the health condition of the animal, then determining if the identified irregular parameter is related to an illegal activity.Type: ApplicationFiled: December 20, 2017Publication date: January 16, 2020Inventors: Saeed ALNOFELI, David KHAYATI
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Publication number: 20200015741Abstract: A method of measuring efficacy of test treatment of an autoimmune disease in an animal in a vivarium is described. Animal activity data is collected at multiple times during the night. Sequential time regions of the night are identified as high-activity, activity-drop, or low-activity regions. Embodiments are described to quantify a drop, during the night, of an animal's activity level. These quantified activity-drop scalars for consecutive nights are accumulated in an animal health dataset. This dataset is compared to healthy animals, a standard of care or a reference treatment for the first disease to determine efficacy of the test treatment. One embodiment quantifies an activity-drop by fitting straight-line curves through the data in the three nightly regions. Other embodiment uses a Fourier transform on a circle, LASSO, RANSAC or regression analyses for curve fitting. Another embodiment compares areas under data curves in the regions. Animals may be housed in cages with other animals.Type: ApplicationFiled: September 21, 2019Publication date: January 16, 2020Applicant: Vium, IncInventors: Laura Schaevitz, Daniel J. Ford
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Publication number: 20200015742Abstract: In order to objectively grasp a stress state of a user and to prevent postpartum depression, biological gas information is acquired via a network, where the biological gas information indicates a concentration of acetophenone of the user and is obtained by a sensor that detects acetophenone released from a skin surface of the user. From a memory storing information including an upper limit of a normal range of the concentration of acetophenone per unit period, the information indicating the upper limit of the normal range is read out. When a frequency in the unit period with which the concentration of acetophenone of the user exceeds the upper limit of the normal range is determined to have an increasing tendency based on the biological gas information obtained during a pregnancy period of the user, the information related to stress of the user is output to an information terminal of the user.Type: ApplicationFiled: September 25, 2019Publication date: January 16, 2020Inventors: YUKARI NISHIYAMA, MASAHIKO TSUKUDA, YASUAKI OKUMURA
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Publication number: 20200015743Abstract: In order to objectively grasp a stress state of a user and to prevent postpartum depression, biological gas information is acquired via a network, where the biological gas information indicates a concentration of heptadecane of the user and is obtained by a sensor that detects heptadecane released from a skin surface of the user. From a memory storing information including an upper limit of a normal range of the concentration of heptadecane per unit period, the information indicating the upper limit of the normal range is read out. When a frequency in the unit period with which the concentration of heptadecane of the user exceeds the upper limit of the normal range is determined to have an increasing tendency based on the biological gas information obtained during a pregnancy period of the user, the information related to stress of the user is output to an information terminal of the user.Type: ApplicationFiled: September 25, 2019Publication date: January 16, 2020Inventors: YUKARI NISHIYAMA, MASAHIKO TSUKUDA, YASUAKI OKUMURA
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Publication number: 20200015744Abstract: A detector and inclusion location method that uses a reconstruction technique to target and localize sparse small-sized but high-contrast objects, such as a tumor inside tissue. The reconstruction technique applied, can dramatically enhance the property contrast of the tumors or abnormal inclusions by ten to one hundred fold. The reconstruction technique enables the use of nonlinear imaging ill-posed techniques that are function-oriented imaging techniques without any need for structural prior knowledge.Type: ApplicationFiled: July 15, 2019Publication date: January 16, 2020Inventor: Qianqian Fang
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Publication number: 20200015745Abstract: According to one embodiment, an electronic device includes a biological information acquisition processor, a body condition estimation processor, and a motion change detector. The biological information acquisition processor acquires biological information of a living body including information about the living body. The body condition estimation processor estimates a body condition of the living body based on the biological information. The motion change detector detects a motion change of the living body based on the biological information. The body condition estimation processor corrects a reference value used during body condition estimation or changes a body condition estimation method based on the motion change of the living body.Type: ApplicationFiled: February 20, 2019Publication date: January 16, 2020Inventors: Mami Saito, Takashi Sudo, Yasuhiro Kanishima
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Publication number: 20200015746Abstract: The present document describes a wearable device for monitoring one or more vital signs of a human body, the device comprising a carrier suitable for being worn around an abdominal part of the body, and an electrode arrangement comprising a plurality of conductive electrodes, wherein the electrodes are arranged on the carrier such as to be brought in contact with a skin of the body in use, and wherein the electrodes are arranged for receiving electric physiologic signals from the body for enabling monitoring of a membrane potential of one or more muscles in the body, wherein the electrodes comprise one or more first electrodes arranged on the carrier such as to be in contact with a side part of a torso of the body, such as to receive via said first electrodes a first electrical signal indicative of a membrane potential of a thoracic diaphragm of the body; wherein the carrier further comprises at least one second electrode in addition to the one or more first electrodes, the at least one second electrode beingType: ApplicationFiled: September 20, 2017Publication date: January 16, 2020Inventors: Sidarto BAMBANG OETOMO, Martijn TEN BHÖMER, Claudia CAPARELLI
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Publication number: 20200015747Abstract: Various embodiments of a sealed package and a method of forming such package are disclosed. The package can include a non-conductive substrate that includes a cavity disposed in a first major surface. A cover layer can be disposed over the cavity and attached to the first major surface of the non-conductive substrate to form a sealed enclosure. The sealed package can also include a feedthrough that includes a via between a recessed surface of the cavity and a second major surface of the substrate, and a conductive material disposed in the via. An external contact can be disposed over the via on the second major surface of the non-conductive substrate, where the external contact is electrically connected to the conductive material disposed in the via. The sealed package can also include an electronic device disposed within the sealed enclosure that is electrically connected to the external contact.Type: ApplicationFiled: September 24, 2019Publication date: January 16, 2020Inventors: David A. RUBEN, Craig L. SCHMIDT
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Publication number: 20200015748Abstract: A sensor pod assembly comprising a gel pad, a gel pad cap, a piezoelectric sensor, a base plate, a base plate support, a wiring harness, a battery, a noise attenuating backing, and a charging component; said gel pad comprising a top and bottom, said bottom having a flat bottom and a concave recess; said flat bottom acoustically contacting said piezoelectric sensor; said piezoelectric sensor secured to a first side of said base plate support, and a second side of said base plate support secured to said base plate, a wiring harness and a battery connected to said base plate, and a charging component having exposed annular rings on the exterior side of said sensor pod assembly; a noise attenuating backing compressing the charging component against the base plate; and a gel pad cap having an outer face and an inner face, said inner face in contact with said base plate support.Type: ApplicationFiled: December 14, 2017Publication date: January 16, 2020Inventors: Bret Kline, Peter Bakema
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Publication number: 20200015749Abstract: This disclosure generally relates to medical devices that include a sensor transmitter assembly that includes a sensor assembly including a sensor module where a first sensor including a first sensor head having at least one first sensor contact pad is combined with a second sensor including a second sensor head having at least one second sensor contact pad. The sensor transmitter assembly also includes a transmitter assembly positioned on a top of the sensor assembly to form a single unit, the transmitter assembly having at least one transmitter contact disposed on a base of the transmitter assembly, where the first sensor contact pad(s) and the second sensor form a connection path with the transmitter contact(s).Type: ApplicationFiled: September 23, 2019Publication date: January 16, 2020Inventors: David C. Antonio, Eric Allan Larson, Jose J. Ruelas, Akhil Srinivasan
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Publication number: 20200015750Abstract: A needle assembly includes an elongated, hollow, hypodermic needle and a temperature measurement device at least partially disposed within the needle. The temperature measurement device comprises a plurality of parallel thermal sensors collectively retained in a fixed relationship within a common dielectric sheath. Each thermal sensor includes a temperature-sensing region which is capable of generating a voltage in proportion to the sensed temperature. The temperature-sensing regions for the plurality of thermal sensors are arranged in an offset relationship within the hypodermic needle, with each temperature-sensing region located at a different position relative to the sharpened tip of the hypodermic needle. Accordingly, in use, needle assembly is designed to compile temperature measurements at multiple locations along the length of the needle, thereby yielding a comprehensive and accurate temperature profile of the body into which the hypodermic needle is inserted.Type: ApplicationFiled: July 11, 2019Publication date: January 16, 2020Inventors: Michael Pike, Herb Dwyer