Abstract: A gas sensor includes: a sensor element including a bottomed tubular solid electrolyte, a detection electrode, and a reference electrode; and a heater for heating the solid electrolyte. The reference electrode includes an inner detection section on an entire periphery in a circumferential direction at an endmost position on a tip side on the reference electrode, an inner connecting section on an entire periphery in the circumferential direction at an endmost position on a base end side on the reference electrode, and an inner lead section on a part in the circumferential direction at a position where the inner detection section is connected to the inner connecting section. A formation region in the circumferential direction of the inner lead section is reduced stepwise from the inner detection section toward the inner connecting section.

Abstract: A sensor element includes: an element base including: a ceramic body made of an oxygen-ion conductive solid electrolyte, and having a gas inlet at one end portion thereof; at least two internal chambers located inside the ceramic body, and communicating with the gas inlet under predetermined diffusion resistance; an electrochemical pump cell including an electrode located on an outer surface of the ceramic body, an electrode facing the internal chambers, and solid electrolytes located therebetween; and a heater buried in the ceramic body; and a porous leading-end protective layer surrounding a first range at least including a part from a leading end surface to two internal chambers close to the gas inlet of the element base. A single heat insulating space is interposed between the leading-end protective layer and a portion of the element base in which the two internal chambers are located.

Abstract: A sensor element includes: an element base including: a ceramic body made of an oxygen-ion conductive solid electrolyte, and having an inlet at one end portion thereof; at least one internal chamber located inside the ceramic body, and communicating with the inlet under predetermined diffusion resistance; an electrochemical pump cell including an electrode located on an outer surface of the ceramic body, an electrode facing the internal chamber, and a solid electrolyte located therebetween; and a heater buried in the ceramic body; and a porous leading-end protective layer surrounding a first range at least including a leading end surface and a region to be coped with water-induced cracking specified in advance. A single heat insulating space is interposed between the leading-end protective layer and a whole side surface of the element base at least in the above region.

Abstract: A sensor element includes: a main pump cell constituted by an inner electrode provided to face a first inner space into which a measurement gas is introduced, an external electrode provided on an element surface, and a solid electrolyte therebetween; and a measurement pump cell constituted by a measurement electrode provided to face a second inner space communicated with the first inner space, an external electrode, and a solid electrolyte therebetween. A diffusion resistance from a gas inlet to the inner electrode is 200 to 1000 cm?1. For the first inner space and a unit electrode part of the inner electrode, a space length is 2.5 to 10 mm, a space thickness is 50 to 300 ?m, an electrode length/the space length is 0.5 to 1.0, and an electrode width/the space width is 0.5 to 1.0.

Abstract: A gas sensor system (100) comprising at least one first field effect transistor (200) comprising first source and drain electrodes and at least one second field effect transistor (300) comprising second source and drain electrodes different from the first source and drain electrodes.

Abstract: A method for correcting nucleotide incorporation signals for fluid potential effects or disturbances arising in nucleic acid sequencing-by-synthesis includes: disposing a plurality of template polynucleotide strands in a plurality of defined spaces disposed on a sensor array, the template polynucleotide strands having a sequencing primer and a polymerase bound therewith; exposing the template polynucleotide strands to a series of flows of nucleotide species flowed through a fluid manifold, the fluid manifold comprising passages for flowing nucleotide species and a branch passage for flowing a solution, the branch passage comprising a reference electrode and a sensing electrode; obtaining a plurality of nucleotide incorporation signals corresponding to the plurality of defined spaces, the nucleotide incorporation signals having a signal intensity related to a number of nucleotide incorporations; and correcting at least some of the plurality of nucleotide incorporation signals for fluid potential effects or dis

Abstract: In an embodiment, a device includes: an electrode configured to change a contact angle of a liquid droplet above the electrode when a first voltage is applied to the electrode; a sensing film overlaying the electrode, wherein the electrode is configured for assessment of a state of the liquid droplet based on a second voltage sensed at the electrode; a reference electrode above the electrode, the reference electrode configured to provide a reference voltage; and a microfluidic channel between the electrode and the reference electrode, wherein the microfluidic channel is configured to manipulate the liquid droplet using the electrode.

Abstract: In a floating gate semiconductor nanostructure biosensor and a method for manufacturing the biosensor, the nanostructure biosensor includes a substrate, an insulating layer, a nanostructure, a source electrode and a drain electrode, a floating gate and a biological sensing material. The insulating layer is formed on the substrate. The nanostructure is protruded from the insulating layer. The source electrode and the drain electrode are formed on the insulating layer and dispose the nanostructure therebetween. The floating gate has a metal pattern or a polysilicon pattern, and extends with contacting the nanostructure. The biological sensing material has a first end combined with an immobile molecule on the floating gate, and a second end combined with a bio molecule.

Abstract: A sensor with a nanowire heater may be provided. The sensor may be patterned in a device layer of a Silicon on Insulation (SOI) wafer comprising a backside layer and a Buried Oxide (BOX) layer and the nanowire heater may be patterned in the device layer of the SOI wafer adjacent to the sensor. Next, metal routing may be created for the SOI wafer and a bond carrier wafer may be provided on a metal routing side of the SOI wafer. The backside layer may then be ground until the BOX layer is exposed. Then the device layer may be patterned through the BOX layer to expose the sensor and the nanowire heater. A dielectric may be deposited covering at least one of the following: the sensor; and the nanowire heater.

Abstract: A method for controlling sub-acute ruminal acidosis (SARA) in a dairy cow. The method includes placing a pH sensor in a rumen of the dairy cow, obtaining pH data of the rumen utilizing the pH sensor, receiving the pH data by one or more processors, calculating a first average of the pH data and a second average of the pH data utilizing the one or more processors, generating a plurality of pH classes based on a plurality of predefined pH ranges, generating a plurality of sodium bicarbonate classes based on a plurality of predefined sodium bicarbonate mass ranges, designing a fuzzy control system based on a set of rules, and determining an amount of bicarbonate sodium to add to a water supply of the dairy cow utilizing the fuzzy control system based on the first average and the second average.

Abstract: Various implementations disclosed herein relate to automated processing of nucleic acids and electrophoretic sample preparation. An exemplary disposable cassette for automated molecular processing may include a base housing, a central channel arranged in the housing, and an elution module configured to be received in central channel and to divide the central channel into a first chamber and a second chamber. The elution module comprises a housing having a proximal side, a distal side and an elution module channel passing from the proximal side to the distal side. The elution module also comprises a first membrane attached to a proximal side of the elution module, a second membrane attached to a distal side of the elution module, and a porthole in fluid communication with the elution module channel and configured for receiving a sample.

Abstract: A method for detecting the zeta potentials of nanopores and nanoparticles mainly uses an electrokinetic mechanism with a force balance exerted on particles in a nanopore and a current sensing technology to measure the zeta potential of the nanopore accurately, and then uses the measured zeta potential of the pore to further measure the zeta potential of the electrically charged nanoparticle passing through the pore. This method does not need to analyze the detailed spectrum of the current blockage signals and purchase expensive standard item particles, so that this method has high accuracy and less limitation than the conventional method and achieves the effects of simplifying the measurement process and lowering the measurement cost significantly. For soft nanoparticles, this method can sense the zeta potential of particles more accurately to improve the value of the method of this invention.

Abstract: A volumetric microfluidic injector for capillary electrophoresis (CE) for highly repeatable sample injection has been designed and built to eliminate known injection bias in hydrodynamic injection. A defined volume from 1-10 nL or 0.1-100 nL of sample is confined in a defined region of a micro-valve PDMS microfluidic injector chip and electrophoretic potential is applied to drive sample into a separation device such as an embedded fused silica capillary for separation and detection. Using a 75 ?m ID capillary, the RSD of an absorbance peak area as low as 1.32% (n=11) is obtained. As a comparison, the time-dependent injection was tested using the same chip which resulted in an inferior repeatability.

Abstract: An insulated pipe includes an elongated tube having a first end, a second end, and a sidewall extending therebetween, including an inner surface and an outer surface. The insulated pipe also includes an insulating member covering a portion of the outer surface of the sidewall and a planar moisture sensor. The planar moisture sensor is positioned in the insulating member or between the insulating member and the outer surface of the tube sidewall. The planar moisture sensor includes: a first electrode having a flat conductive member having an inner surface and an outer surface; a second electrode spaced apart from the first electrode having a flat conductive member having an inner surface and an outer surface, and a dielectric layer. The dielectric layer includes an absorbent dielectric polymer material positioned between and in electrical contact with the inner surfaces of the first electrode and the second electrode.

Abstract: Disclosed herein is a differential probe, a testing device having at least one such differential probe, and a method for producing the same. The differential probe has a first half-probe and a second half-probe, at least one conductor loop pair having a conductor loop of each half-probe being shaped mirror-inverted relative to each other and, in respect of a mirror-inverted arrangement thereof on respective sides of a mirror plane. The conductor loops are oriented parallel to the mirror plane, are arranged offset relative to each other in an offset direction, also parallel to the mirror plane, wherein the conductor loops overlap in part in the direction normal to the mirror plane.

Abstract: A detection device, a detecting method for the detection device, and a detecting system are provided. The detection device includes: a first interdigital transducer and a second interdigital transducer, wherein the first interdigital transducer is arranged opposite to the second interdigital transducer, and a surface wave of the first interdigital transducer is transmitted in a direction toward the second interdigital transducer; and a reaction layer arranged between the first interdigital transducer and the second interdigital transducer.

Abstract: A method and system for determination of geometric features in an object is provided. The method includes receiving at least one geometric feature response to an ultrasound beam incident on the object. The incident ultrasound beam is produced from one of a plurality of ultrasound transducers. Further, a volumetric representation of the object is generated based on a plurality of object parameters. The volumetric representation of the object and a plurality of transducer parameters are used to generate a predicted beam traversal path in the object. The predicted beam traversal path is utilized to generate a temporal map of predicted time of flight geometric feature response to the ultrasound beam. A position on the volumetric representation of the object is determined as the location of the geometric feature, when the received geometric feature response is equivalent to the predicted time of flight geometric feature response corresponding to the position.

Abstract: A system and method directed to displaying images and presenting the data from the phased array ultrasonic testing (PAUT) inspection of a plurality of welded joints within a welded object. The system includes an engine comprising memory, a graphical user interface (GUI), an export module, a transformation module, and a merger module each operably coupled to one another. The export module is used to extract images and data from the PAUT inspection of the welded joints. The exported information is used by the transformation module to create a multi-dimensional representation of the PAUT inspected welded joint for each joint. The merger module combines the information from the export module and the transformation module into an evaluation report for each PAUT inspected welded joint and assembles the evaluation report into a master report for analysis. The system may be communicatively coupled over a network using a network interface.

Abstract: The present invention relates to detector arrangement that is capable of monitoring vibrations within a construction (20) of an organic material. The detector arrangement (10) comprises an acoustic sensor and a processing unit (13) having a processor (14). An acoustic sensor monitors vibrations within the construction when mounted to the construction (20) and provides a signal based on said monitored vibrations. The processor (14) determines an intensity threshold based on the signal, and when the signal has a component with an intensity higher than the intensity threshold, the processor determines that insect infestation is detected in the construction, if the signal component has a certain frequency content, comprises a wave-form that is essentially that of insect infestation vibration, and has an intensity pattern over time, which intensity pattern indicates insect infestation. Else, the processor maintains the acoustic sensor to monitor vibrations.

Abstract: Integrated probes and probe systems suitable for attachment to a robotic arm of a remotely operated vehicle are disclosed. The probes and probe systems serve to perform cleaning operations and both cathodic protection (CP) voltage measurements and ultrasonic testing (UT) thickness measurements at an underwater surface. The cathodic protection measurement system includes one or more electrically conductive legs that extend outwardly from the probe. These legs are arranged about a cleaning tool and an ultrasonic sensor. When the integrated probe contacts the underwater surface, at least one leg contacts the surface, thereby providing a desired distance between the probe and the underwater surface for efficient cleaning and UT inspection. The underwater surface can be cleaned and CP and UT measurements can all be performed using a single, integrated probed during a single operation, without having to reposition the probe.

Abstract: A capacitive transducer includes an element including a plurality of cells. Each of the cells includes a first electrode and a vibrating membrane including a second electrode opposed to the first electrode via a gap. The second electrode of one of the plurality of cells is electrically connected to the second electrode of at least one adjoining cell by first electrical wiring. The first electrical wiring over the gap of a first cell provided on a periphery of the element among the plurality of cells has a structure different from that of the first electrical wiring over the gap of a second cell provided on an inner side of the element than the first cell is.

Abstract: A method for measuring the concentration of a gas includes heating a first gas with a pulse of light, the pulse of light having a wavelength absorbed by the first gas, wherein the first gas exerts pressure on a flexible membrane. The method includes receiving a first signal indicating a first deflection of the membrane, wherein the first deflection is due to a change in pressure of the first gas and receiving a second signal indicating a second deflection of the membrane occurring after the first signal, wherein the second deflection is due to the change in pressure of the first gas. The method includes determining a difference between the first signal and the second signal and, based on the difference between the first signal and the second signal, determining a first concentration of the first gas.

Abstract: A method and system is disclosed for measuring a wideband loop sensitivity SL(f) for an acoustic transducer in an acoustic probe. A pulse signal is employed as a wideband reference signal Vr(t); and, in a pulse-echo measurement a corresponding wideband echo signal Ve(t) is obtained. A normalized loop frequency response {circumflex over (X)}(f) for the acoustic transducer is defined as a ratio of a Fourier Transform of the Ve(t) to a Fourier Transform of the Vr(t). A wideband loop sensitivity SL(f) for the acoustic transducer is defined as an absolute square of the {circumflex over (X)}(f) in decibel.

Abstract: An electric measurement circuit possesses an electrical reaction leg for forming an oscillator from a resonator, and furthermore possesses a measurement leg the input of which is supplied by the electrical reaction leg. The measurement leg contains an adjustable phase shifter so that an additional excitation force that is applied to the resonator in the measurement leg can be adjusted in phase quadrature with respect to an excitation force that is applied to the resonator in the electrical reaction leg. Such an electrical measurement circuit is particularly suitable for forming a photoacoustic gas detector.

Abstract: Described are a method and apparatus for diluting a chromatographic sample. The method includes repeating an alternating acquisition of sample fluidic plugs each having an incremental volume of sample and diluent fluidic plugs each having an incremental volume of diluent to obtain a stack of alternating sample and diluent fluidic plugs. The stack is inserted into a flow of a mobile phase in a chromatography system. Alternatively, the method includes repeating the steps of injecting an incremental volume of sample into a chromatographic system flow and providing an incremental volume of mobile phase into the chromatographic system flow. In either implementation, the dilution ratio of the sample equals the sum of the incremental volumes of the sample and the diluent or mobile phase divided by the sum of the incremental volumes of the sample.

Abstract: Before start of analysis, a user inputs pipe capacity difference relative to reference pipe capacity and separation conditions, such as a mobile phase flow rate. A control unit calculates retention time shift from the pipe capacity difference and the flow rate. The control unit controls sample injection and data processing units so as to start collection of chromatogram data when a correction time has passed from the time point of sample injection in the case in which the value of the retention time shift is a positive value, and to perform sample injection when a correction time has passed from the time point at which the collection of chromatogram data is started in the case in which the value of the retention time shift is a negative value. Retention time shift caused by difference in the pipe capacity is corrected even when the mobile phase flow rate is different.

Abstract: A septum containing a duckbill valve assembly includes a plurality of elastomeric ribs extending from the body of the septum to the duckbill valve assembly. When inserted into an injection port cavity, force generated by an interference fit between the body of the septum and the cavity is transmitted by the ribs to the duckbill valve assembly. The ribs are configured to reversibly collapse at a hinge point when a needle is inserted through the duckbill valve assembly and are spaced to assist in centering the needle in the duckbill valve assembly. The ribs reduce wear on the duckbill valve assembly by reducing the concentration of compressive forces at higher inlet pressures while maintaining sufficient compressive force to close the duckbill valve assembly at lower inlet pressures.

Abstract: A chromatography system includes a modulator, a chromatograph, a cooler, and a detector. The chromatograph is connected to the modulator by a first heated transfer line. The detector is connected to the modulator by a second heated transfer line. The cooler is connected to the modulator. The modulator is arranged outside of the chromatograph.

Abstract: There is provided a system for separation of analytes in a solution. The system encompasses a cartridge or trapping column enclosing a sorbent for binding the analytes in the solution and a conduit establishing a fluid link to a valve having a holding-loop to achieve elution through the cartridge at low pressures. Prior to entry into the loop, the eluent is diluted or modified by a confluent flow stream. The valve is switchable to a position following the elution from the cartridge for emptying the holding loop through an outlet port at high pressures comparable to those required for chromatographic columns. The system may use parallel gradient formation/elution to stagger analyses so that essentially the only analytical phase that hinders a 100% duty cycle is the time required for moving the first analyte from the valve and to the detector.

Abstract: Valves, pumps, detectors, sample loops, fraction collectors and the like are individually incorporated into modules that are mountable at individual mounting sites on a base unit which also supports one or more chromatography columns. Each module includes fluid connections to other modules and a microcontroller joining the module to a computed and monitor through an electronic connector at each mounting site. The fluid connections between the modules and the column(s) are removed from the electronic connections and accessible to the user. A software platform may recognize the modules and their locations, coordinate fluid connections between the modules, and provide a variety of control, monitoring, data generating and data processing functions to generate chromatographic data. The software platform may also provide graphical tools for designing chromatographic methods from a library of phases.

Abstract: A hybrid trap including a replaceable open-tubular capillary trap followed by a packed trap is used to collect, preconcentrate, and recover a sample, such as VOCs and SVOCs found in air. The capillary stage prevents losses and carryover of the heavy fraction and can also collect the particles in air that contain the heavier SVOCs, also preventing them from reaching the packed stage. The packed stage traps lighter organic compounds that are not as prone to carryover due to channeling. The capillary and packed traps together provide quantitative recovery of compounds boiling from as low as ?50° C. to as high as 600° C. The sample can be directly desorbed onto the GC column, which avoids losses and contamination caused by other approaches that thermally desorb samples through transfer lines and rotary valves more remote to the GC oven.

Abstract: The present invention relates to reagents suitable in the mass spectrometric determination of analyte molecules such as carbohydrates as well as adducts of such reagents and analyte molecules and applications of said reagents and adducts. Further, the present invention relates to methods for the mass spectrometric determination of analyte molecules.

Abstract: An ionizer includes an ionization probe (21) provided with a capillary (211), a metallic slender tube (212), and a nebulizing gas pipe (213). The ionization probe (21) is equipped to perform ESI-based ionization of components in a liquid sample. An electroconductive capillary (22) is disposed at a position forward in a flow direction of a nebulized flow of the liquid sample from the ionization probe (21). A high voltage from a high voltage power supply (23) is applied to the electroconductive capillary (22) to induce corona discharge so that the components in the liquid sample are ionized by the APCI as well. At the time of tuning the ionizer, a standard sample solution is provided through the electroconductive capillary (22), and a high voltage from the high voltage power supply (23) is applied to the electroconductive capillary (22) so that components in the standard sample solution are ionized by the ESI or due to an ion molecular reaction with solvent molecular ions produced in the ionization probe (21).

Abstract: The present invention is a method for automated mass-directed separation of two or more components from a sample, which method comprises defining a solvent gradient by its changing composition; subjecting said solvent gradient to mass spectrometry (MS) to generate gradient signal(s); passing a gradient including at least part(s) of the defined gradient across a packed chromatography column to which a sample has been applied; subjecting the eluent exiting said column to MS to generate sample signal(s); generating a spectrum by subtracting the gradient signals from the sample signals across a selected range of m/z values; and directing a fraction collector to collect fraction(s) each comprising a separated component based on the spectrum generated.

Abstract: Embodiments of methods for producing and testing aqueous gas streams within a self-pressurized flow cell are disclosed. The aqueous gas streams comprise mixtures of aqueous salt precursor and aqueous acid precursor that are mixed in-line and introduced to the self-pressurized flow cell to produce aqueous gases. Once in the self-pressurized flow cell, the precursor mixture formed from the mixed aqueous salt precursor and the aqueous acid precursor may react with the sample. Both the sample and the reacted aqueous solution may be subjected to a variety of real-time tests, such electrochemical tests and in line characterization techniques. These embodiments allow for the concentrations of the aqueous salt precursor and the aqueous acid precursor to be accurately and precisely maintained while allowing for increased safety when handling and testing the various toxic aqueous gas streams produced.

Abstract: A system for preventing explosions in a transported object which includes containers and packages with an imbedded port or window, a semipermeable cloth or filter layer that promotes air flow through natural physical and gaseous processes and access to internally generated trace particles and vapor plumes from contained explosive material, the integrity of which is protected by a mesh, grill, or woven matrix, and which may be impregnated with colorific luminescent chemicals that fluoresce, darken, or illuminate in the presence of explosive-containing material.

Abstract: The purpose of the present disclosure is to provide a computer system, a plant diagnosis method, and a program in which the measurement accuracy of the temperature of each site of a target is improved. The computer system acquires a visible light image and an infrared image that are imaged by a camera, identifies a region, in the visible light image, which corresponds to a predetermined site of a plant imaged by the camera, identifies a region, in the infrared image, which corresponds to the identified region in the visible light image, and diagnoses the plant based on the temperature of the identified region in the infrared image.

Abstract: There is provided a biofilm capacitance microbial electrochemical cell (MEC) sensor to measure organic carbon in water and wastewater rapidly and accurately, represented by the 5-day biochemical oxygen demand (BOD5). The MEC runs at charging (open circuit) and discharging (close circuit) conditions alternately to improve the sensitivity, response time and accuracy. The detectable BOD5 concentrations with the biofilm-capacitance MEC range from 5 to 250 mg/L (R2>0.9). The MEC sensor enables BOD5 measurements at every 2 minutes (1 minute charging and 1 minute discharging), indicating semi-continuous quantification of organic carbon in water and wastewater.

Abstract: A process is provided for the determination of oil dispersant effectiveness. A submersible dispersant sensing platform is passed across a body of water. The platform has a plurality of sensors including a multichannel fluorometer and a particle size analyser, and each sensor produces an output data stream. The body of water is continuously analysed at a predetermined depth profile below the surface of the body of water. Hydrodynamic and environmental condition data is collected proximate in time and location to the output data from the dispersant sensing platform. The environmental condition data includes one or more of ambient temperature, body or water temperature, salinity of the body of water, wind speed, location, mixing energy of the body of water and derivatives thereof. Oil and dispersant data is provided which includes characteristics of the dispersant and of oil samples prior to the application of the dispersant.

Abstract: The present invention relates to a liquid treatment system having a sensor comprising a body, the body having a sensing material disposed therein, the sensing material being subject to a change in size in response to a composition of a liquid flowing therethrough; an actuating means disposed within the body and associated with the sensing material; wherein the actuating means is movable between a first position and a second position in response to the change in size of the sensing material to thereby mechanically actuate a switch member, such that when the actuating means is in the first position, flow of an actuating stream of the liquid is allowed by the switch member to thereby hydraulically actuate operation of the liquid treatment system; and when the actuating means is in the second position, flow of the actuating stream of the liquid is prevented by the switch member.

Abstract: The present disclosure relates to a method for determining the methane index of a hydrocarbon-containing combustion gas mixture which has natural gas or biogas, having the steps: flowing the gas mixture through a measuring assembly; determining a first value of a first measurement variable related to a viscosity of the gas mixture; determining a second value of a second measurement variable related to a density of the gas mixture; determining a pressure value of the gas mixture, said pressure value belonging to the first value and the second value; determining a temperature value of the gas mixture, said temperature value belonging to the first value and the second value; and determining the methane index as a function of the first value, the second value, the pressure value, and the temperature value.

Abstract: A system includes a sensor configured to be disposed within a reservoir of a machine having moving parts that are lubricated by a liquid in the reservoir. The sensor is configured to obtain a measurement of the liquid that is representative of at least one of a quantity or quality of the liquid in the reservoir. The system also includes a device body operably coupled to the sensor. The device body has a processing unit that is operably coupled to the sensor and configured to generate first data signals representative of the measurement of the liquid. The device body also includes a transmitter that is configured to wirelessly communicate the first data signals to a remote reader.

Abstract: The present application provides a method and system for the characterization of properties of liquids, particularly petroleum and petroleum liquids. The method and system can be used to take measurements of the liquid directly in a storage container, without exposing the contents of the container to the external environment.

Abstract: An automated analyzer for reagent cards having a leading end, a trailing end and a length between the leading end and the trailing end comprises a travel surface assembly having a card travel surface and an edge. A test analyzing mechanism is adjacent to the travel surface, and a waste receptacle is adjacent to the edge below the travel surface. The waste receptacle has a side and a waste cavity. A ramp member positioned below the travel surface has an end and a sloped surface, and is movable between an extended position where the sloped surface extends into the waste cavity, and a retracted position where the end is spaced from the side a distance greater than the length of the reagent card. A moving mechanism operably coupled with the ramp member is configured to move the ramp member between the extended position and the retracted position.

Abstract: The purpose of the present invention is to provide a method for treating biomolecules and a method for analyzing biomolecules with which it is possible to effectively suppress the clog of nanopores. The present invention is a method for treating biomolecules for analysis in which nanopores are used, wherein the method includes a step for preparing a sample solution that includes ammonium cations represented by a prescribed formula and biomolecules in which at least a portion of the higher-order structure has been fused.

Abstract: Methods for diagnosing, treating, and monitoring the treatment of fusariosis or scedosporiosis are described. The methods can include detecting the presence of one or more volatile organic compounds (VOCs) in the breath of subjects suspected of having fusariosis or scedosporiosis.

Abstract: A cartridge device (10) for collecting and analysing a breath condensate is disclosed. The device (10) comprises a condensation zone (12) to condense exhaled breath from a subject and cooling means operably connected to the condensation zone (12). The device includes further discrete regions (13) for detection of analyte and measurement of analyte. The condensation zone (12) has a fluid exit connecting the condensation zone (12) to the discrete regions (13).

Abstract: Distributed liquid-flow systems—in which flow spreads out from a system inlet and traverses the system through multiple discrete, smaller flow channels—are constructed to minimize variations in flow-resistance-induced pressure drop from the system inlet to entrances to the flow channels. Because flow-driving pressure will be more uniform at the entrances to the flow channels, flow along the channels will be more uniform. Disclosed embodiments may be particularly suitable or advantageous for use in gas-exchange/artificial lung devices.

Abstract: A business method for use in classifying patient samples. The method includes steps of collecting case samples representing a clinical phenotypic state and control samples representing patients without said clinical phenotypic state. Preferably the system uses a mass spectrometry platform system to identify patterns of polypeptides in said case samples and in the control samples without regard to the specific identity of at least some of said polypeptides. Based on identified representative patterns of the state, the business method provides for the marketing of diagnostic products using representative patterns. The present invention relates to systems and methods for identifying new markers, diagnosing patients with a biological state of interest, and marketing/commercializing such diagnostics. The present invention relates to systems and methods of greater sensitivity, specificity, and/or cost effectiveness.

Abstract: This application provides methods to quantitate drug incorporation into DNA and of simultaneously measuring DNA methylation levels. Drugs include nucleoside analog DNA methyltransferase inhibitors.