Patents Issued in February 13, 2020
  • Publication number: 20200048366
    Abstract: In one aspect, the invention provides methods of inhibiting the effects of MASP-2-dependent complement activation in a living subject. The methods comprise the step of administering, to a subject in need thereof, an amount of a MASP-2 inhibitory agent effective to inhibit MASP-2-dependent complement activation. In some embodiments, the MASP-2 inhibitory agent inhibits cellular injury associated with MASP-2-mediated alternative complement pathway activation, while leaving the classical (C1q-dependent) pathway component of the immune system intact.
    Type: Application
    Filed: February 22, 2019
    Publication date: February 13, 2020
    Inventors: Gregory A. Demopulos, Thomas Dudler, Hans-Wilhelm Schwaeble
  • Publication number: 20200048367
    Abstract: Provided herein are excipients capable of effectively reducing the viscosity of polypeptide (e.g., therapeutic polypeptide) formulations. The viscosity reducing excipients are dipeptides containing arginine at the carboxy terminus and N-acetylated serine or N-acetylated proline at the N-terminus. Glutamate-arginine is also disclosed as a viscosity-reducing dipeptide. Among the disclosed methods, methods of reducing the viscosities of such formulations are also provided.
    Type: Application
    Filed: April 27, 2018
    Publication date: February 13, 2020
    Applicant: Amgen Inc.
    Inventors: Neeraj Jagdish AGRAWAL, Pavan GHATTYVENKATAKRISHNA, Sekhar KANAPURAM, Christopher James SLOEY
  • Publication number: 20200048368
    Abstract: Bi-specific fusion proteins with therapeutic uses are provided, as well as pharmaceutical compositions comprising such fusion proteins, and methods for using such fusion proteins to repair or regenerate damaged or diseased tissue. The bi-specific fusion proteins generally comprise: (a) a targeting polypeptide domain that binds to a target molecule; and (b) an activator domain that detectably modulates tissue regeneration.
    Type: Application
    Filed: July 29, 2019
    Publication date: February 13, 2020
    Inventors: Ulrik Nielsen, Thomas Wickham, Birgit Schoeberl, Brian Harms, Bryan Linggi, Matthew Onsum, Byron DeLaBarre, Shaun M. Lippow
  • Publication number: 20200048369
    Abstract: Polypeptide compositions comprising a human immunoglobulin constant region with a modified IgG4 hinge region having an N-terminal deletion of 1, 2, 3, 4, 5 amino acids, relative to a native human IgG4 hinge sequence are provided. In some embodiments the hinge sequence further comprises the amino acid substitution S228P (Eu numbering). Polypeptides comprising the modified sequence optionally comprise a binding moiety specific for an epitope that is present on red blood cells; and can provide for reduced agglutination of hematopoietic cells compared to a comparable polypeptide with a native hinge region.
    Type: Application
    Filed: October 26, 2017
    Publication date: February 13, 2020
    Inventors: Jie Liu, Irving L. Weissman, Ravindra Majeti
  • Publication number: 20200048370
    Abstract: The present invention describes novel immunoglobulin compositions that co-engage at least two antigens, e.g. a first and second antigen, or, as outlined herein, three or four antigens can be bound, in some of the scaffold formats described herein. First and second antigens of the invention are herein referred to as antigen-1 and antigen-2 respectively (or antigen-3 and antigen-4, if applicable. As outlined herein, a number of different formats can be used, with some scaffolds relying combinations of monovalent and bivalent bindings.
    Type: Application
    Filed: March 25, 2019
    Publication date: February 13, 2020
    Inventors: Gregory Moore, Rumana Rashid, John Desjarlais
  • Publication number: 20200048371
    Abstract: Provided herein are tumor-associated antigen (TAA) presentation inducer constructs comprising at least one innate stimulatory receptor (ISR)-binding construct that binds to an ISR expressed on an antigen-presenting cell (APC), and at least one TAA-binding construct that binds directly to a first TAA that is physically associated with tumor cell-derived material (TCDM) comprising one or more other TAAs. The ISR-binding construct and TAA-binding construct are linked to each other, and the TAA presentation inducer construct induces a polyclonal T cell response to the first TAA and to the one or more other TAAs. Also provided are methods of using the TAA presentation inducer constructs, for example, in the treatment of cancer.
    Type: Application
    Filed: March 29, 2018
    Publication date: February 13, 2020
    Inventors: David M. Mills, Eric Escobar-Cabrera
  • Publication number: 20200048372
    Abstract: A multivalent antibody fusion protein which comprises an immunoglobulin moiety, for example a Fab or Fab? fragment, with a first specificity for an antigen of interest, and further comprises two single domain antibodies (dAb) with specificity for a second antigen of interest, wherein the two single domain antibodies are linked by a disulfide bond. There is also provided particular dual specificity antibody fusion proteins comprising a Fab or Fab? fragment and one or more single domain antibodies which may be stabilised by a disulfide bond therebetween.
    Type: Application
    Filed: July 11, 2019
    Publication date: February 13, 2020
    Inventors: Ralph Adams, Laura Hancock, Sam Philip Heywood
  • Publication number: 20200048373
    Abstract: A method for producing an additive for a rubber composition, including the step of preparing modified cellulose fibers including introducing one or more compounds selected from unsaturated group-containing alkylene oxide compounds and unsaturated group-containing glycidyl ether compounds to cellulose-based raw materials in the presence of a base, via an ether bonding, and thereafter carrying out a finely fibrillating treatment, wherein the modified cellulose fibers are cellulose fibers bound to one or more substituents, via an ether bonding, selected from substituents represented by the following general formula (1) and substituents represented by the following general formula (2): —CH2—CH(OH)—R1 (1); and —CH2—CH(OH)—CH2—(OA)n—O—R1 (2), wherein the modified cellulose fibers have cellulose I crystal structure.
    Type: Application
    Filed: March 6, 2018
    Publication date: February 13, 2020
    Applicant: KAO CORPORATION
    Inventors: Shotaro Shibata, Yutaka Yoshida, Hisaho Kawahara, Yoshiaki Kumamoto
  • Publication number: 20200048374
    Abstract: An extrusion dryer for a rubbery polymer includes a cylinder equipped with a hopper for injection of the rubbery polymer at one end and a die at the other end. A screw is rotatably arranged inside of the cylinder, the screw having a shaft and a spiral flight formed on an outer surface of the shaft. The shaft includes multiple zones, each including a conveyance section and a compression section. In the zone closest to the die, the outer diameter of the shaft at the conveyance section is smaller than the outer diameter at the compression section.
    Type: Application
    Filed: October 23, 2017
    Publication date: February 13, 2020
    Applicant: ZEON CORPORATION
    Inventors: Masao NAKAMURA, Kenichiro SUMIURA, Junichi IMAI
  • Publication number: 20200048375
    Abstract: A method for producing a hydrogenated conjugated diene polymer latex includes: a hydrogenation step of dissolving or dispersing a hydrogenation catalyst containing a platinum group element in a latex of a conjugated diene polymer to hydrogenate a carbon-carbon unsaturated bond in the polymer; an insoluble complex formation step of complexing the platinum group element with a complexing agent to form an insoluble complex; and an insoluble complex removing step of continuously feeding the latex which has undergone the insoluble complex formation step to a centrifuge machine and continuously performing a centrifugation operation to continuously remove the insoluble complex from the latex and continuously discharge the insoluble complex out of the centrifuge machine. In the insoluble complex removal step the feed rate of the latex to the centrifuge machine is adjusted to 0.5 to 15 m3/hour, and the centrifugal force in the centrifugation operation is adjusted to 200 to 10,000 G.
    Type: Application
    Filed: January 18, 2018
    Publication date: February 13, 2020
    Applicant: ZEON CORPORATION
    Inventors: Kentaro ONO, Chikara KATANO, Yasuaki WATANABE
  • Publication number: 20200048376
    Abstract: Provided is a composite resin material that yields a resin molded body which has not only a low volume resistivity but also excellent electroconductivity and/or antistatic properties and whose volume resistivity is unlikely to be increased even when subjected to, for example, a washing treatment with ozone water. The composite resin material contains a polychlorotrifluoroethylene and carbon nanotubes and has an average particle diameter of 500 ?m or smaller.
    Type: Application
    Filed: October 6, 2017
    Publication date: February 13, 2020
    Inventors: Hirokazu YAMAMOTO, Kazuya NINOMIYA, Hirotaka ITAMI, Takafumi NAKAGAWA, Kentaro MIYOSHI, Katsunori TAKADA, Toru SAKAI
  • Publication number: 20200048377
    Abstract: Provided is a thermosensitive phosphazene-based polymer including an amino acid ester moiety, a polyethyleneglycol moiety, and a moiety including a sulfate group linked directly or by a linker in a predetermined ratio, a method of preparing the same, and a hydrogel-formable composition including the same. For example, a hydrogel formed from the composition may be used for tissue regeneration or drug delivery or used as a storage, a body tissue regeneration inducer, or a filler in a body.
    Type: Application
    Filed: August 9, 2019
    Publication date: February 13, 2020
    Inventors: Soo Chang Song, Bo Bae Seo
  • Publication number: 20200048378
    Abstract: The present invention relates to a process for the preparation of a procatalyst suitable for preparing a catalyst composition for olefin polymerization, said process comprising the steps of: Step A) providing or preparing a Grignard compound; Step B) contacting in the Grignard compound with a silane compound to give a first intermediate reaction product being a solid support; Step C) activating said solid support, comprising two sub steps: Step C1) contacting the solid support obtained in step B) with at least one first activating compound and a second activating compound; and Step C2) a second activation step by contacting the activated solid support obtained in step C1) with an activating electron donor; to obtain a second intermediate reaction product; Step D) reacting the second intermediate reaction product obtained in step C) with a halogen-containing Ti-compound, optionally an activator and at least one internal electron donor in several sub steps to obtain said procatalyst.
    Type: Application
    Filed: September 14, 2017
    Publication date: February 13, 2020
    Inventors: Akhlaq Moman, Inaamul Haq Siddiqui, Sudhakar R. Padmanabhan, Osamah Al-Humaidan, Haitham Al-Enazi
  • Publication number: 20200048379
    Abstract: Novel polyethylene copolymers having a relatively high comonomer partitioning tendency are disclosed as are methods for their preparation. The comonomer partitioning tendency is the tendency for a copolymer to have comonomer in the higher molecular weight chains. Novel metrics for describing the comonomer partitioning tendency are also disclosed.
    Type: Application
    Filed: October 16, 2019
    Publication date: February 13, 2020
    Applicant: Univation Technologies, LLC
    Inventor: Roger L. Kuhlman
  • Publication number: 20200048380
    Abstract: To provide a method for producing a multicomponent copolymer with which a multicomponent copolymer having excellent rupture strength can be obtained, and a multicomponent copolymer, a rubber composition and a tire having excellent rupture strength. The method is a method for producing a multicomponent copolymer having a conjugated diene unit, a non-conjugated olefin unit and an aromatic vinyl unit, comprising adding a conjugated diene compound in divided portions into a reactor containing a catalyst and at least one selected from the group consisting of a non-conjugated olefin compound and an aromatic vinyl compound. The multicomponent copolymer is obtained with the production method. The rubber composition comprises the multicomponent copolymer as a rubber component. The tire uses the rubber composition.
    Type: Application
    Filed: October 17, 2019
    Publication date: February 13, 2020
    Applicant: BRIDGESTONE CORPORATION
    Inventors: Shigenaga TAKANO, Aya Yanagisawa, Olivier Tardif, Yasuo Horikawa
  • Publication number: 20200048381
    Abstract: Provided is an ethylene/alpha-olefin copolymer having excellent environmental stress crack resistance.
    Type: Application
    Filed: November 2, 2017
    Publication date: February 13, 2020
    Applicant: LG Chem, Ltd.
    Inventors: Soon Ho Sun, Yo Han Bae, Hyeong Il Lee, Yi Young Choi, Bog Ki Hong, Sung Min Lee, Sun Mi Kim, Jin Young Park
  • Publication number: 20200048382
    Abstract: Disclosed herein is a catalyst system including a first catalyst compound represented by Formula (I): and a second catalyst compound that is a bridged or unbridged metallocene. M is a group 4 metal. X1 and X2 are independently a univalent C1-C20 hydrocarbyl, C1-C20 substituted hydrocarbyl, a heteroatom or a heteroatom-containing group, or X1 and X2 join together to form a C4-C62 cyclic or polycyclic ring structure. R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 is independently hydrogen, C1-C40 hydrocarbyl, C1-C40 substituted hydrocarbyl, a heteroatom or a heteroatom-containing group, or two or more of R1, R2, R3, R4, R5, R6, R7, R8, R9, or R10 are joined together to form a C4-C62 cyclic or polycyclic ring structure, or a combination thereof. Q is a neutral donor group. Methods of polymerizing with the catalyst system to produce polyolefin polymers are also disclosed.
    Type: Application
    Filed: October 4, 2017
    Publication date: February 13, 2020
    Inventors: Matthew W. Holtcamp, Crisita Carmen H. Atienza, Charles J. Harlan, Xuan Ye, Matthew S. Bedoya, David F. Sanders, David A. Cano, Subramaniam Kuppuswamy, Michelle E. Titone, Ching-Tai Lue, Laughlin G. McCullough, Rohan A. Hule
  • Publication number: 20200048383
    Abstract: This invention relates to a catalyst system including the reaction product of a support (such as a fluorided silica support that preferably has not been calcined at a temperature of 400° C. or more), an activator and at least two different transition metal catalyst compounds; methods of making such catalyst systems, polymerization processes using such catalyst systems and polymers made therefrom.
    Type: Application
    Filed: October 4, 2017
    Publication date: February 13, 2020
    Inventors: Rohan A. Hule, Antonios K. Doufas, Derek W. Thurman, Crlsita Carmen H. Atienza, Matthew W. Hoitcamp, David F. Sanders, Matthew S. Bedoya
  • Publication number: 20200048384
    Abstract: A high density, high polydispersity polyethylene having improved properties, and a process of producing same.
    Type: Application
    Filed: January 12, 2018
    Publication date: February 13, 2020
    Applicant: Univation Technologies, LLC
    Inventors: Peter S. Martin, John F. Szul, Roger L. Kuhlman, Mahsa McDougal, C. Jeff Harlan, Timothy M. Boller
  • Publication number: 20200048385
    Abstract: The invention provides compositions, each comprising an ethylene/alpha-olefin interpolymer, which has a reduced level of a low density, low molecular weight oligomeric fraction, as indicated by an HCC value, as described herein, and reduced levels of inorganic content or lower Tm. The invention also provides processes for forming such interpolymers.
    Type: Application
    Filed: October 16, 2019
    Publication date: February 13, 2020
    Inventors: Frank J. Cerk, Rongjuan Cong, Shrikant Dhodapkar, Selim Yalvac, Morgan M. Hughes, Timothy W. Gambrel, Yi Jin
  • Publication number: 20200048386
    Abstract: Provided is a method of making a collection of polymer beads comprising (a1) forming a first collection of monomer droplets in an aqueous medium in a container, wherein the first collection of monomer droplets has volume-average diameter DAV1 and has uniformity coefficient less than 1.3; (a2) forming a second collection of monomer droplets in the aqueous medium in the container, wherein the second collection of monomer droplets has volume-average diameter DAV2 and has uniformity coefficient less than 1.3, wherein DAV1 and DAV2 differ by 10 ?m or more; wherein either step (a1) and step (a2) are performed simultaneously; or step (a2) is performed after step (a1), while the first collection of monomer droplets remains in the container; or a combination thereof; and (b) after steps (a1) and (a2), polymerizing the monomer droplets by suspension polymerization to form the polymer beads.
    Type: Application
    Filed: November 6, 2017
    Publication date: February 13, 2020
    Inventors: John David Finch, James A. Jagodzinski
  • Publication number: 20200048387
    Abstract: A melt-formable ethylene-vinyl alcohol copolymer composition contains: (A) an ethylene-vinyl alcohol copolymer; (B) an alkali metal compound; and (C) an iron compound; wherein the weight ratio of the alkali metal compound (B) to the iron compound (C) on a metal basis is 10 to 100,000. The viscosity of the melt-formable ethylene-vinyl alcohol copolymer composition decreases with time during melt forming, rendering it excellent in long-run formability.
    Type: Application
    Filed: October 22, 2019
    Publication date: February 13, 2020
    Applicant: Mitsubishi Chemical Corporation
    Inventors: Keisuke TAKESHITA, Takuya NAKAJIMA, Daichi NISHIMURA
  • Publication number: 20200048388
    Abstract: The presently claimed invention relates to novel monomers which can be used for preparing polymers which are useful as dispersants for pigments and fillers, as wetting agent and as thickening agents in liquid compositions.
    Type: Application
    Filed: October 24, 2017
    Publication date: February 13, 2020
    Applicant: BASF SE
    Inventors: Huiguang KOU, Clemens AUSCHRA, Frank PIRRUNG, Dario PERERA-DIEZ
  • Publication number: 20200048389
    Abstract: The present invention aims to provide a photocurable resin composition which rapidly cures by irradiation with active energy rays such as ultraviolet rays and is excellent in adhesion to an electrolyte membrane which is a hard-to-bond material. A photocurable resin composition includes the following ingredients (A) to (C): ingredient (A): a polymer having one or more (meth)acryloyl groups and having a polyisobutylene skeleton containing a —[CH2C(CH3)2]— unit, ingredient (B): a photoradical polymerization initiator, and ingredient (C): a compound having a (meth)acryloyl group and a cationic polymerizable functional group in one molecule.
    Type: Application
    Filed: April 13, 2018
    Publication date: February 13, 2020
    Inventor: Tetsunori SOGA
  • Publication number: 20200048390
    Abstract: Provided herein are polymer materials that find use in, for example, delivery of short-chain fatty acids. In particular, polymers are provided that form stable nanoscale structures and release their payload, for example, by cleavage of a covalent bond (e.g., via hydrolysis or enzymatic cleavage). The polymers are useful, for example, for delivery of payloads (e.g., SCFAs) to the intestine for applications in health and treatment of disease, and have broad applicability in diseases linked to changes in the human microbiota including inflammatory, autoimmune, allergic, metabolic, and central nervous system diseases, among others.
    Type: Application
    Filed: April 17, 2018
    Publication date: February 13, 2020
    Inventors: Jeffrey A. Hubbell, Ruyi Wang, D. Scott Wilson, Cathryn R. Nagler, Catherine Plunkett
  • Publication number: 20200048391
    Abstract: The present invention relates to a process for preparing a polymer with a mass Mw of less than 300 000 g/mol (especially between 1000 and 300 000 g/mol), comprising a step (E) of controlled radical polymerization in which the following are placed in contact in an aqueous medium in which are dispersed surfactant micelles: ethylenically unsaturated hydrophilic monomers predominantly present in the aqueous medium; partially water-soluble ethylenically unsaturated hydrophobic monomers different from the preceding monomers, at least partly present in the surfactant micelles, and having a solubility in the aqueous medium at least equal to that of hexyl acrylate; at least one radical polymerization initiator; and at least one radical polymerization control agent.
    Type: Application
    Filed: October 17, 2019
    Publication date: February 13, 2020
    Inventors: Simon HARRISSON, James WILSON
  • Publication number: 20200048392
    Abstract: Described is a polymerizable polymer composition compri a) a copolymerizable macromer, b) a (meth)acrylate ester monomer; and c) a polyfunctional type I photoinitiator.
    Type: Application
    Filed: February 13, 2018
    Publication date: February 13, 2020
    Inventors: Stefan H. Gryska, Joon Chatterjee, Deepti Gopalakrishnan, George W. Griesgraber, Larry R. Krepski, Babu N. Gaddam
  • Publication number: 20200048393
    Abstract: Polar modifier systems based on a blend of DTHFP, ETE, TMEDA, DMTHFMA and/or functionally similar compounds with BDMAEE and SMT are used to make block copolymers having high levels of pendant vinyl double bond repeat units, which is through highly selective 1,2-bond butadiene addition, low vinylcyclopentane formation, unimodal narrow molecular weight distribution, and a low level of randomized co-monomer repeat units. The block copolymers have very high levels of 1,2-vinyl content and high 3,4-vinyl bond addition of the conjugated diene monomer and low vinylcyclopentane content. The polar modifier systems provide a fast polymerization rate, with a unimodal narrow molecular weight distribution. The polar modifier systems allow operation at a higher temperature than in prior art systems, which reduces cooling requirements.
    Type: Application
    Filed: September 8, 2017
    Publication date: February 13, 2020
    Applicant: Dynasol Elastómeros, S.A. de C.V.
    Inventors: Daniel Abraham Elizarrarás Maya, Christopher J. Hardiman, Sergio Corona Galván, Sergio Alberto Moctezuma Espiricueto, Luis Antonio Rodríguez Guadarrama
  • Publication number: 20200048394
    Abstract: The present invention relates to a hardenable polymer composition containing at least one acrylate compound, at least one silyl-terminated polymer and at least one photoinitiator, to the use of the polymer composition as or in an adhesive, a sealant, gasket, knifing filler or coating composition, and to an adhesive composition, a sealant composition, a gasket composition, a knifing filler composition or a coating composition comprising the polymer composition.
    Type: Application
    Filed: October 13, 2017
    Publication date: February 13, 2020
    Applicant: BASF SE
    Inventors: Bernd HOEVEL, Angelika ROSER, Juergen PFISTER, Thomas CHRIST
  • Publication number: 20200048395
    Abstract: A process for making an oxymethylene polymer comprising polymerizing at least one compound capable of forming —CH2O— repeat units (monomer) in the presence of at least one ester of the general formula I (ester): R1—CO—O—R2 (I) wherein R1 can be hydrogen, wherein R1 and R2 are independently of each other linear or branched C1 to C10 alkyl C5 to C7 cycloalkyl —[R3-0-]nR4 wherein R3 is a linear or branched C2 to C5 alkylen and R4 is a linear of branched C1 to C5 alkyl and n is an integer of from 1 to 5. and in the presence of at least one Lewis acid.
    Type: Application
    Filed: January 9, 2018
    Publication date: February 13, 2020
    Inventors: Thomas Heitz, Minlu ZHANG, Achim STAMMER, JongMoon KIM, In-Gi CHO, Jin-Sang CHOI
  • Publication number: 20200048396
    Abstract: The present invention relates to a process for producing a polyurethane, comprising the reaction of a polyol composition (PZ) comprising a polyol (P1) with a polyisocyanate composition (PIZ-1) comprising a polyisocyanate (I1) to obtain a hydroxyl-terminated prepolymer (PP1) and the reaction of the prepolymer (PP1) obtained with a polyisocyanate composition (PIZ-2) comprising a polyisocyanate (I2) and at least one chain extender (K1) to obtain a polyurethane (PU1), wherein the molar ratio of the OH groups in the components of the polyol composition (PZ) to the isocyanate groups in the components of the polyisocyanate composition (PIZ-1) in the reaction in step (i) is in the range from 1.3:1 to 10:1. The present invention further relates to polyurethanes obtainable or obtained by such a process, and to the use of the polyurethanes for production of shaped bodies, adhesives, coatings, hoses, films, nonwoven articles or fibers.
    Type: Application
    Filed: March 20, 2018
    Publication date: February 13, 2020
    Applicant: BASF SE
    Inventors: Sebastian RICHTER, Frank SCHAEFER, Johannes POPPENBERG, Hendrik WAGNER
  • Publication number: 20200048397
    Abstract: The invention provides polyurethane and polyisocyanurate foams and methods for the preparation thereof. More particularly, the invention relates to closed-celled, polyurethane and polyisocyanurate foams and methods for their preparation. The foams are characterized by a fine uniform cell structure and little or no foam collapse. The foams are produced with a polyol premix composition which comprises a combination of a hydrohaloolefin blowing agent, a polyol, a silicone surfactant, and a non-amine catalyst used alone or in combination with an amine catalyst.
    Type: Application
    Filed: February 14, 2019
    Publication date: February 13, 2020
    Inventors: Michael Van der Puy, David J. Williams, Clifford P. Gittere
  • Publication number: 20200048398
    Abstract: The invention relates to a process for the preparation of a thixotropic composition comprising polyurea particles, said process comprising contacting and reacting in a liquid medium reactants to form a polyurea and precipitating the polyurea to form polyurea particles, wherein acoustic vibration is applied during contacting of the reactants or as a post-treatment on the formed polyurea particles or both. The invention further relates to a thixotropic composition obtainable by the process, in particular thixotropic composition comprising high amounts of polyurea particles and optionally a polymer resin having high thixotropic efficiency. The compositions can be used, in particular as a masterbatch, in preparation of i.a. coating compositions.
    Type: Application
    Filed: November 7, 2017
    Publication date: February 13, 2020
    Applicant: ALLNEX Netherlands B.V.
    Inventors: Martin BOSMA, Petrus Johannes Maria David ELFRINK, Enrico Richardus August RENSEN, Richard Hendrikus Gerrit BRINKHUIS
  • Publication number: 20200048399
    Abstract: Disclosed are high strength polyurethane foam compositions and methods of making them. In one aspect, the inventive polyurethane foams include strength enhancing additives comprising one or more polycarbonate polyols derived from the copolymerization of CO2 and one or more epoxides. In one aspect, the inventive methods include the step of substituting a portion of the polyether polyol in the B-side of a foam formulation with one or more polycarbonate polyols derived from the copolymerization of CO2 and one or more epoxides.
    Type: Application
    Filed: August 15, 2019
    Publication date: February 13, 2020
    Inventors: Scott D. Allen, Vahid Sendijarevic, Aisa Sendijarevic
  • Publication number: 20200048400
    Abstract: This invention relates to a polyol component P), to a process for preparing rigid polyurethane foams by using said polyol component P) and also to the rigid polyurethane foams themselves.
    Type: Application
    Filed: March 23, 2018
    Publication date: February 13, 2020
    Applicant: BASF SE
    Inventors: Sirus ZARBAKHSH, Johann KLASSEN, Mark ELBING
  • Publication number: 20200048401
    Abstract: This invention provides stable polyol compositions at all states and these compositions are stable for at least 24 hours, in some cases for more than 6 months. There is also provided polyol mixture compositions that may be uniformly blended under manufacturing conditions within a time period of less than eight hours, typically less than two hours, i.e., stable-polyol mixtures. The invention provides a composition and a method for making stable polyurethane foams. The polyol mixture comprises at least two polyols of different polyoxyethylene content, catalyst, at least one ethoxylated alcohol of the following formula: RO(CH2CH2O)nH, wherein R is C1-C31 linear or branched alkyl, n is an integer equal to or greater than 1; and wherein the at least one ethoxylated alcohol has a hydrophilic-lipophilic balance (HLB) value equal to or greater than about 3.7.
    Type: Application
    Filed: November 10, 2017
    Publication date: February 13, 2020
    Inventors: Jennifer Elizabeth Antoline Al-Rashid, Udo Banseberg, Stephanie Lynne Britton, Christian Brandl
  • Publication number: 20200048402
    Abstract: A process for preparing a phosphorus-functional polyethercarbonate polyol, comprising reacting a polyethercarbonate polyol having unsaturated groups with a phosphorus-functional compound of formula (Ia): wherein X=O or S; and wherein R1 and R2 are selected from the group consisting of C1-C22 alkyl, C1-C22 alkoxy, C1-C22 alkylsulfanyl, C6-C70 aryl, C6-C70 aryloxy, C6-C70 arylsulfanyl, C7-C70 aralkyl, C7-C70 aralkyloxy, C7-C70 aralkylsulfanyl, C7-C70 alkylaryl, C7-C70 alkylaryloxy, C7-C70 alkylarylsulfanyl, or wherein R1 and R2 are bridged to one another directly and/or via heteroatoms and are selected from the group consisting of C1-C22 alkylene, oxygen, sulfur, and NR5, wherein R5 is hydrogen, C1-C22 alkyl, C1-C22 acyl, C7-C22 aralkyl, or C6-C70 aryl radical. A process for preparing a phosphorus-functional polyurethane polymer is disclosed.
    Type: Application
    Filed: April 3, 2018
    Publication date: February 13, 2020
    Inventors: Thomas Ernst Mueller, Christoph Guertler, Kai Laemmerhold, Muhammad Afzal Subhani, Burkhard Koehler, Walter Leitner
  • Publication number: 20200048403
    Abstract: An isocyanate composition according to the present invention contains an isocyanate compound of formula (1) and/or (2) (wherein R1 represents a hydrogen or a monovalent organic group, and R2 represents a monovalent organic group), and, relative to the total mass of the isocyanate compound in the composition, 1.0 ppm by mass to 10% by mass of a compound of formula (3): R13—(COO—R14)a (wherein R13 represents an organic group with a valence of a, R14 represents a monovalent organic group, and a represents an integer of 1 or 2), which is different from the isocyanate compound, and/or, 1.0 ppm by mass to 10% by mass of a compound having an UV absorption in an area of decamer or higher isocyanates in a measurement spectrum of gel permeation chromatography.
    Type: Application
    Filed: October 13, 2017
    Publication date: February 13, 2020
    Applicant: ASAHI KASEI KABUSHIKI KAISHA
    Inventors: Nobuhisa MIYAKE, Masaaki SHINOHATA, Atsushi OHKUBO, Koichi NAKAOKA, Yuji KOSUGI
  • Publication number: 20200048404
    Abstract: A photo-curable composition includes a blocked isocyanate represented by the general formula (1): A-B-C??(1) (wherein, in the formula (1), A and C each independently represent a group represented by the formula (2) below, and B represents a group represented by the formula (3) below: wherein, in the formula (2), R1 represents a hydrogen atom or a methyl group, R2 represents a hydrocarbon group which may have a substituent, and L1 represents a divalent hydrocarbon group; and in the formula (3), R3, R4, and R5 each independently represent a divalent hydrocarbon group which may have a substituent, 1?a+b?50).
    Type: Application
    Filed: August 28, 2019
    Publication date: February 13, 2020
    Inventor: Seiji Okada
  • Publication number: 20200048405
    Abstract: The present invention provides an isocyanate composition including an isocyanate compound having an ethylenically unsaturated bond, a compound represented by formula (1) (in the formula, R1 represents an a-valent organic group, R2 represents a monovalent organic group, a represents an integer of 1 or 2), and/or a compound having a UV absorption in a spectral region of a decamer or higher isocyanate measured by gel permeation chromatography; and an isocyanate composition including an isocyanate compound having an ethylenically unsaturated bond, or a compound having at least one unsaturated bond other than an unsaturated bond constituting an aromatic ring or an inert compound such as a hydrocarbon compound or the like and having a carbon-carbon unsaturated bond other than an unsaturated bond constituting an aromatic ring; or the like.
    Type: Application
    Filed: October 13, 2017
    Publication date: February 13, 2020
    Applicant: ASAHI KASEI KABUSHIKI KAISHA
    Inventors: Nobuhisa MIYAKE, Masaaki SHINOHATA, Atsushi OHKUBO, Koichi NAKAOKA, Yuji KOSUGI
  • Publication number: 20200048406
    Abstract: The present invention discloses silylated polyurethanes obtainable by reacting at least one polyols, at least one polyisocyanates, at least one amide-functionalized silanes of the general formula (I) as described herein and their preparation methods, curable compositions comprising the silylated polyurethanes and their use as adhesive, sealant, spray foam and/or coating.
    Type: Application
    Filed: October 18, 2019
    Publication date: February 13, 2020
    Inventors: Rok Brisar, Udo Kragl, Jan-Erik Damke, Johann Klein, Esteban Mejia
  • Publication number: 20200048407
    Abstract: Gem-dialkyl cyclooctene monomers, telechelic prepolymers prepared by ring opening metathesis polymerization of the monomers, and polymers such as polyurethanes comprising the reaction product of the prepolymer and a co-monomer such as a polyisocyanate.
    Type: Application
    Filed: October 17, 2019
    Publication date: February 13, 2020
    Inventors: Marc A. Hillmyer, Yanzhao Wang
  • Publication number: 20200048408
    Abstract: Embodiments of the present invention relate to a composition containing a polymer or oligomer (A) and an initiator (B), wherein the polymer or oligomer (A) contains no alkyl groups of 5 or more carbon atoms, contains at least one type of structural unit selected from the group consisting of a structural unit containing an aromatic amine structure and a structural unit containing a carbazole structure, and contains, at one or more terminals, a structural unit containing a thienyl group which may have a substituent, and a degree of solubility of the composition is capable of being changed by applying heat, light, or both heat and light.
    Type: Application
    Filed: October 3, 2016
    Publication date: February 13, 2020
    Inventors: Kazuyuki KAMO, Hirotaka SAKUMA, Kenichi ISHITSUKA, Tomotsugu SUGIOKA, Yuki YOSHINARI, Ryo HONNA, Daisuke RYUZAKI
  • Publication number: 20200048409
    Abstract: Disclosed is a method for preparing polylactone by ring opening, belonging to the technical fields of organic catalysis and polymer materials. The invention proposes a new catalytic mechanism, wherein an organic alcohol is used as an initiator to initiate ring opening polymerization of a cyclic monomer under the catalysis of an organic catalyst to obtain a polylactone; and the catalyst is a pyridinium salt. The present invention has the advantages of non-toxic reaction, simple conditions and controllable process; further, the invention can obtain a narrow molecular weight distribution in the absence of solution polymerization, and can effectively inhibit the occurrence of the transesterification compared with the catalysis of 4-(N,N-dimethylamino)pyridine.
    Type: Application
    Filed: April 24, 2018
    Publication date: February 13, 2020
    Inventors: Kai GUO, Hui ZHU, Zhenjiang LI, Fulan WEI, Siming CHEN, Yu GAO
  • Publication number: 20200048410
    Abstract: A phosphinate copolycarbonate having units of the formula (1) wherein each Ra is independently a halogen atom, C1-10 alkyl, C1-10 haloalkyl, C1-12 alkoxy, C6-10 aryl, or C6-12 haloaryl, each Xa is as defined herein, Re and Rf are independently a halogen atom, C1-10 alkyl, C1-10 haloalkyl, C1-10 alkoxy, C1-10 haloalkoxy, C2-10 alkenyl, or C3-10 cycloalkyl, each Rg is a substituted or unsubstituted C6-18 aryl, C1-10 alkyl, C1-10 haloalkyl, C1-10 alkoxy, C1-10 haloalkoxy, C2-10 alkenyl, C3-10 cycloalkyl, C6-10 aryl, or C6-12 haloaryl, Ara and Arb are each independently the same or different C6-18 aryl, a, e, and f are each independently 0 to 4, or 0 to 2 or 0, c is 0 or 1, and x and y represent the molar ratio of each unit in the phosphinate copolycarbonate, and are 0.5:99.5 to 99.5:0.5, or 1:99 to 99:1, or 10:90 to 90:10, or 20:80 to 80:20.
    Type: Application
    Filed: April 13, 2018
    Publication date: February 13, 2020
    Inventor: Jordi Calveras
  • Publication number: 20200048411
    Abstract: The present application relates to a quaternary nitrogen compound comprising a nitrogen heterocycle wherein: at least one polymeric substituent is bound to a ring atom of said heterocycle; and, an aromatic photoremovable group (PRG) is directly bound to a quaternary nitrogen ring atom of said heterocycle, the release of said aromatic photoremovable group under UV irradiation yielding a tertiary amine. The application further relates to the use of said quaternary nitrogen compound as a latent catalyst in a curable composition, the curing of which may be catalyzed or co-catalyzed by tertiary amines.
    Type: Application
    Filed: October 21, 2019
    Publication date: February 13, 2020
    Inventors: Ligang Zhao, Enrique Del Rio Nieto, Francisco Vera Saz, Christina Berges
  • Publication number: 20200048412
    Abstract: The present invention is directed to branched reactive water-soluble polymers comprising at least two polymer arms, such as poly(ethylene glycol), attached to a central aliphatic hydrocarbon core molecule through heteroatom linkages. The branched polymers bear at least one functional group for reacting with a biologically active agent to form a biologically active conjugate. The functional group of the branched polymer can be directly attached to the aliphatic hydrocarbon core or via an intervening linkage, such as a heteroatom, -alkylene-, —O-alkylene-O—, -alkylene-O-alkylene-, -aryl-O—, —O-aryl-, (—O-alkylene-)m, or (-alkylene-O—)m linkage, wherein m is 1-10.
    Type: Application
    Filed: October 1, 2019
    Publication date: February 13, 2020
    Inventors: Michael D. Bentley, Xuan Zhao, Xiaoming Shen, William D. Battle, III
  • Publication number: 20200048413
    Abstract: A method produces polyamide fine particles by polymerizing a polyamide monomer (A) in the presence of a polymer (B) at a temperature equal to or higher than the crystallization temperature of a polyamide to be obtained, wherein the polyamide monomer (A) and the polymer (B) are homogeneously dissolved at the start of polymerization, and polyamide fine particles are precipitated after the polymerization. Polyamide fine particles have a number average particle size of 0.1 to 100 ?m, a sphericity of 90 or more, a particle size distribution index of 3.0 or less, a linseed oil absorption of 100 mL/100 g or less, and a crystallization temperature of 150° C. or more. In particular, a polyamide having a high crystallization temperature includes fine particles having a smooth surface, a narrow particle size distribution, and high sphericity.
    Type: Application
    Filed: May 7, 2018
    Publication date: February 13, 2020
    Inventor: Itaru Asano
  • Publication number: 20200048414
    Abstract: The disclosure generally relates to filaments and in particular, filaments for use in fused filament fabrication to prepare 3D printed articles. The filaments may be prepared from a polymer composition comprising: A) 55 to 95 weight percent semi-aromatic copolyamide having a melting point; and B) 5 to 45 weight percent amorphous copolyamide having a melting point.
    Type: Application
    Filed: October 12, 2017
    Publication date: February 13, 2020
    Inventor: Kai Qi
  • Publication number: 20200048415
    Abstract: The present invention relates to process intensification, and renewable processing routes for polymer production, for example the solar production of Nylon 6,6 and precursors relevant for the Nylon 6,6 production (such as hydrogen, adiponitrile and hexanediamine). The invention deals with the integration of solar energy into the process, specifically aims at petrochemical-free processing, and deals with reformulation of traditional (linear) processes into circular (closed cycle) processing approaches and sustainable processes.
    Type: Application
    Filed: March 20, 2018
    Publication date: February 13, 2020
    Inventors: Sophia HAUSSENER, Miguel Antonio MODESTINO