Abstract: A catalyst system has been designed that disrupts the sedimentation process. The catalyst system achieves this by saturating key feed components before the feed components are stripped into their incompatible aromatic cores. The efficacy of this disruptive catalyst system is particularly evident in a hydrocracker configuration that runs in two-stage-recycle operation. The catalyst is a self-supported multi-metallic catalyst prepared from a precursor in the hydroxide form, and the catalyst must be toward the top level of the second stage of the two-stage system.

Abstract: A treatment process for remediating a contaminated liquid containing more than 5 ppm hydrogen sulfide (H2S) and substantially without formation of precipitate, includes steps of steps of adding an aqueous solution containing at least one hydroxide compound at a collective concentration of 35-55 wt % to the contaminated liquid to achieve a concentration of 125-5000 ppm of the hydroxide compounds in the contaminated liquid, adding at least one organic acid and to the liquid to achieve a concentration of 0.01-10 ppm in the contaminated liquid, and dispersing the aqueous solution and the at least one organic acid in the contaminated liquid and allowing the aqueous solution and the at least one organic acid to react with the contaminated liquid for a period of time until a concentration of hydrogen sulfide in the contaminated liquid is reduced to ?5 ppm.

Abstract: A two-step gasification process and apparatus for the conversion of solid or liquid organic waste into clean fuel, suitable for use in a gas engine or a gas burner, is described. The waste is fed initially into a primary gasifier, which is a graphite arc furnace. Within the primary gasifier, the organic components of the waste are mixed with a predetermined amount of air, oxygen or steam, and converted into volatiles and soot. The volatiles consist mainly of carbon monoxide and hydrogen, and may include a variety of other hydrocarbons and some fly ash. The gas exiting the primary gasifier first passes through a hot cyclone, where some of the soot and most of the fly ash is collected and returned to the primary gasifier.

Abstract: Processes for making alkylate gasoline compositions that are more “green” and alkylate gasoline compositions containing “green” renewable naphtha and iso octane are described. Exemplary processes for making alkylate gasoline compositions that are more “green” and compositions of alkylate gasoline compositions containing “green” renewable naphtha, iso octane and iso pentane are described. Such compositions allow a higher mixing ratio of the renewable naphtha and/or a higher Research Octane Number (RON), Motor Octane Number (MON) and vapour pressure compared to not adding a combination of iso-octane and iso-pentane.

Abstract: Provided is a method for operating a fuel gas manufacturing device for stopping the operation in such a manner that the operation can be immediately resumed, while keeping facilities from becoming complex.

Abstract: A process and system for producing an engineered fuel product that meets customer specifications for composition and combustion characteristics is provided. The engineered fuel product is preferably a high-BTU, alternative fuel that burns cleaner than coal or petroleum coke (petcoke) and has significantly reduced NOx, SO2 and GHG emissions.

Abstract: The present application relates to a gear lubricant composition comprising: 97 to 99.9 wt.-% trimethylolpropane triester; and 0.1 to 3 wt.-% at least one additive selected from among anti-wear additives, extreme pressure additives, antioxidants, anti-corrosion additives, metal deactivator additives, antifoams, and mixtures thereof.

Abstract: A lubricant composition is provided containing an oil of lubricating viscosity and a substantially sulfur-free alkyl phosphate amine salt, where at least 30 mole percent of the phosphorus atoms are in an alkyl pyrophosphate salt structure, along with either or both of a conventional phosphorous containing antiwear additive and a glycerol ester. In the phosphate amine salt, at least 80 mole percent of the alkyl groups are typically secondary alkyl groups of 3 to 12 carbon atoms. A method of improving wear over a wide temperature range in a mechanical device is also provided by employing the lubricant composition.

Abstract: Provided is a grease composition including a base oil (A) containing an alkyl naphthalene (A1) and an aliphatic diurea (B) represented by general formula (b1): R1—NHCONH—R3—NHCONH—R2??(b1) (wherein, R1 and R2 each independently represent a monovalent aliphatic hydrocarbon group having 9 to 20 carbon atoms, and R3 represents a divalent aromatic hydrocarbon group having 6 to 18 carbon atoms), wherein a content of the aliphatic diurea (B) is 20 to 30% by mass based on a total amount of the grease composition.

Abstract: The present invention provides a lubricating oil composition not containing ZnDTP but comprising: (a) a base oil; (b) molybdenum dialkyldithiocarbamate; and (c) an organic acid metal salt compound having a metal of Group 8 of a short periodic table, copper, or bismuth as a central metal.

Abstract: The present invention provides a lubricating oil composition for two-wheeled vehicles, which is able to not only suppress a lowering of fatigue life of engine parts while making fuel saving properties (in particular, fuel saving properties at the time of low speed) favorable but also make clutch friction characteristics of two-wheeled vehicles favorable. The present invention is concerned with a lubricating oil composition for two-wheeled vehicles, including a base oil (A) having a viscosity index of 120 or more, an ethylene-propylene copolymer (B), and a metal-based detergent (C), wherein the content of the ethylene-propylene copolymer (B) is 0.

Abstract: The disclosed technology relates to a working fluid for a low global warming potential (GWP) refrigeration system that includes a compressor, where the working fluid includes a polyolester oil, an alkylbenzene oil, and a low GWP refrigerant, and where the ester based lubricant comprises dipentaerythritol esterified with a mixture of carboxylic acids, wherein the mixture of carboxylic acids comprises at least one linear carboxylic acid having 8 to 10 carbon atoms. The disclosed technology provides commercially useful low GWP working fluids (commercially useful working fluids based on low GWP refrigerants) that do not have the solubility and/or miscibility problems commonly seen in low GWP fluids, including high viscosity fluids and applications.

Abstract: A perfume composition comprising at least 2 perfume ingredients, having a known Sandman Classifier (SC) value of at least 1.35. Preferred perfume compositions exhibit SC values of 1.35 to about 150, more particularly 1.35 to about 75, and still more particularly 1.35 to about 3. The composition enhances the quality of sleep.

Abstract: One aspect of the present invention provides a solid detergent, which is manufactured by compressing a mixture including 20 to 40 wt % of a sodium lauryl sulfoacetate powder; 50 to 70 wt % of a sugar powder; and 1 to 10 wt % of a sodium hydrogen carbonate powder, into tablets.

Abstract: A surfactant composition comprising a nonionic surfactant and a supra-amphiphile comprising one or more gemini-like and/or oligomeric-like surfactants, and a method of producing such.

Abstract: An aqueous cleaning composition, which may be suitable for use in cleaning hard surfaces, is described. The aqueous cleaning composition includes an ionic liquid, a surfactant, a quaternary ammonium antimicrobial surfactant, and a substantial amount of water. The ionic liquid includes an N-alkyl-N,N-bis(polyethoxyethanol)-N-aliphatic ammonium salt. Other than an optional fragrance component, the cleaning composition typically is substantially free of volatile organic compounds. The cleaning compositions may also include a chelating agent, such as an aminopolycarboxylate chelating agent.

Abstract: The present invention provides a fiber modifier composed of an internal olefin sulfonate having 17 or more and 24 or less carbons.

Abstract: The disclosure provides compositions and methods for making a colorized solution of an aqueous disinfectant that is both stable in bulk solution and will fade to clear within a predetermined period of time after being applied to a surface, for example as a spray or film. The compositions and methods described here allow an end user to visualize both the extent of coverage and the duration of contact of the disinfectant with the surface, thereby providing more efficient disinfection of the surface.

Abstract: This disclosure relates to a cleaning composition that contains 1) at least one redox agent; 2) at least one first chelating agent, the first chelating agent being a polyaminopolycarboxylic acid; 3) at least one metal corrosion inhibitor, the metal corrosion inhibitor being a substituted or unsubstituted benzotriazole; 4) at least one organic solvent selected from the group consisting of water soluble alcohols, water soluble ketones, water soluble esters, and water soluble ethers; 5) at least one quaternary ammonium hydroxide; and 6) water. This disclosure also relates to a method of using the above composition for cleaning a semiconductor substrate.

Abstract: An aqueous cleaning composition, which may be suitable for use in cleaning hard surfaces, is described. The aqueous cleaning composition includes an N,N-dialkyl-N-aliphatic ammonium hydroxycarboxylate salt, a nonionic surfactant and/or anionic surfactant, an quaternary ammonium antimicrobial surfactant and a substantial amount of water. The aqueous cleaning composition commonly has a pH of no more than about 8 and other than an optional fragrance component, the composition is substantially free of volatile organic compounds. The cleaning compositions may also include a chelating agent, such as an aminopolycarboxylate chelating agent.

Abstract: [Problem to be Solved] An art imparting, to a tablet, excellent functionality that dissolution of a tablet is delayed, that foaming time of a foaming tablet is elongated, that air bubbles generated from a foaming tablet are fined, or that a concentration, in a liquid, of a gas obtained by a foaming tablet is increased is provided. Besides, a method for producing a tablet using the same, and a tablet are provided. [Solution] A composition, for delaying dissolution of a tablet, containing erythritol as an active ingredient, a method for producing a tablet using the same, and a tablet containing erythritol. According to the present invention, excellent functionality can be imparted to a tablet. Besides, a tablet having improved functionality can be easily produced.

Abstract: The present disclosure relates to water-soluble unit dose articles made from a combination of chemically different water-soluble films and containing household care compositions that are at least partially enclosed by the water-soluble films in at least one compartment.

Abstract: Water-soluble unit dose articles containing amphiphilic graft polymer and carboxymethylcellulose. Processes of washing fabrics using the water-soluble unit dose articles.

Abstract: An anti-aging laundering system for fabrics comprising complementary laundering system components (a) a detergent composition, (b) a fabric rinse conditioner, and (c) an ancilliary laundry agent wherein the (b) or (c) provides a combination of (i) a fabric shape retention agent (ii) a fabric drape improver, and (iii) at least one perfume, and wherein said complementary laundering components bear common visual indicia and corresponding instructions to launder fabrics with components (a) and (b) and (c).

Abstract: The present invention relates to hop products, in particular to hop products for flavouring beer and enhancing the aroma of beers, ales and other brewed beverages. More specifically, the present invention relates to such products which are 100% hop-derived and which are readily dispersible in cold wort and beer. As a result of our research, we have determined that polar hop extracts, in particular aqueous extracts of hops, have emulsifying properties for hop oil or hop oil-based hop extract products. This has allowed us to develop hop flavouring and aroma products for beer consisting solely of natural products, without the need for artificial emulsifiers and thickening agents or solvents. Surprisingly and unexpectedly, we have found that our combinations of hop-derived constituents is readily dispersible in cold wort and in beer, even when formulated as a 100% hop-derived paste, and provides excellent hop flavour and aroma to the finished beer.

Abstract: The present application relates to ultrasonic technology, and discloses an ultrasonic beer bubbling container with a good bubble foaming effect and less energy loss. The ultrasonic beer bubbling container comprises a cup body for containing beer and a base provided on the bottom of the cup body. The cup body and the base are separable; an ultrasonic vibrator is arranged in the base, and a through-hole is formed on the bottom of the cup body; wherein a part of the ultrasonic vibrator goes through the through-hole and extends to the cup body, thus to produce ultrasound and directly vibrate the beer so as to foam the beer.

Abstract: The invention concerns a strain of Saccharomyces bayanus subsp. uvarum identified as SERIUS and deposited at the DBVPG with deposit number 36P. The invention further concerns the use of the strain of Saccharomyces bayanus subsp. uvarum identified as SERIUS (DBVPG 36P) as a food inoculate in the production of foods obtained through alcoholic fermentation, and a selection method for yeast strains of the group Saccharomyces adapted to alcoholic fermentation, particularly of grape, consisting of an isolation step for such yeasts from flowers.

Abstract: An apparatus and method for modifying the organoleptic properties of a beverage, such as wine in a bottle, said apparatus having a least one light-source, said light-source applying peak wavelengths at intensities and time durations optimal for modifying said beverage's organoleptic properties with a highly reflective inner surface, a translucent air flow baffle, a translucent liquid barrier, and a controlled oxygen concentration in the bottle headspace.

Abstract: Method and apparatus for biomass cultivation (preferably using algae) incorporating photo bio-reactor (PBR) technology coupled with a heat sink to increase energy efficiency. An external PBR array is coupled to an indoor storage tank system with a volume equal to or greater than the volume of the PBR array. A controller can be used to optimize the growth of biomass by optimizing three key growth parameters: exposure to sunlight, temperature and nutrients. The indoor tank system serves as a reservoir where algae can be protected from harsh ambient conditions, minimizing the cost of energy for heating and cooling that would normally be incurred to accommodate ambient temperature swings caused by weather if the biomass is always stored in an outdoor PBR array. During cold winter nights, the biomass can be brought indoors to conserve thermal energy.

Abstract: The subject invention provides systems and methods for producing bioethanol. More specifically, the present invention includes biological reactors, equipment, and materials for converting carbohydrate sources into alcohol products for use as biofuels and/or sources of electricity in, for example, remote areas.

Abstract: The present disclosure is directed toward membrane biofilm reactors primarily comprising microorganisms that produce chemical fuel products or precursors thereof. Reactors of the present disclosure can primarily comprise acetogens, a methanotrophs, and/or Methanosarcina acetivorans.

Abstract: An object of the present invention is to provide a separation substrate having a high megakaryocyte blocking rate and a high platelet permeation rate, and a cell separation filter and a method for producing a platelet which use the same. The separation substrate of the present invention is a separation substrate including non-woven fabric for separating a platelet from a cell suspension containing a megakaryocyte and the platelet, in which an average pore diameter of the separation substrate is 2.0 ?m to 15.0 ?m, and a thickness of the separation substrate is 10 ?m to 500 ?m.

Abstract: The cell handling device includes a container having a section to store cells; a cell detection unit for detecting a cell stored in the section; a head device for conducting picking of cells, and transfer and release of the picked cells; a control unit; and a determination unit for making a determination of a cell state including at least one of the number, properties, and arrangement of the cells based on a detection result of the cell detection unit. The control unit causes the head device to execute, according to a state determination result obtained by the determination unit, one operation selected from among operation of picking all the cells stored in the section, operation of picking a part of the cells stored in the section, operation of picking a new cell and releasing the cell in the section, and operation of terminating processing of the section.

Abstract: A microelectrode for electroporating an individual cell or embryo that includes a substrate with an electrically insulated surface, a first electrode adjacent to the electrically insulated surface of the substrate, a second electrode adjacent to the electrically insulated surface of the substrate and separated from the first electrode a predetermined distance so as to form a channel, and a liquid medium situated within the channel. The liquid medium is capable of fluidic transport of the cell or embryo through or into the channel and capable of supporting an electric field. The first and second electrodes include surfaces substantially orthogonal to the electrically insulated surface of the substrate with an edge length that is less than or equal to a diameter of the cell or embryo. The predetermined distance may be 50% to 200% of the diameter of the cell or embryo.

Abstract: The claimed invention is directed towards a novel combination cell electroporation/cell culturing apparatus which can be termed a cell culture dish suitable for in vitro electroporation, and towards a device suitable for in vivo electroporation—both useful in methods suitable for the generation of developmentally-activated, pluripotent, pluripotent-like, multipotent, and/or self-renewing cells which are capable of beginning to differentiate in culture into a variety of cell types and capable of further differentiation in vivo. The claimed invention is also directed towards the generation of desirable, differentiating somatic cell populations transplantable to animals or patients, genetic modification of endogenous and exogenous cells, and the treatment of patients suffering from diseases that may be ameliorated by these methods. This invention also provides methods for preventing, treating, or retarding disease, for example, immunodeficiency virus (e.g. HIV-1, HIV-2, SIV, FIV, etc.) infection.

Abstract: Provided are methods of preparing organoids and compositions for use in such methods. In some embodiments, a method of depositing a plurality of the cells into a reservoir are provided, the method comprising depositing a gelatin composition into a reservoir; adding a composition comprising a plurality of cells into the gelatin composition, wherein the composition is added into the gelatin composition at a position below the surface of the gelatin composition and at least a portion of the composition and/or plurality of cells are suspended in the gelatin composition; curing at least a portion of the composition comprising the plurality of cells in the gelatin composition; and removing at least a portion of the gelatin composition in the reservoir, thereby depositing the plurality of cells in the reservoir.

Abstract: The method of culturing cells disclosed herein includes printing cells onto a substrate that includes cell adhesive regions and cell repulsive regions. The cells are suspended in a printing medium to create a cell suspension, and a volume of the cell suspension is loaded into a printer. A cell adhesive region of the substrate is aligned beneath the printing channel of the printer, and droplets of the cell suspension are dispensed from the printing channel directly onto the cell adhesive region. Contact of the dispensed droplets with cell repulsive regions of the substrate is limited, either by targeting of the droplets to the cell adhesive regions, by repulsions generated by the cell repulsive areas, or both. The cells adhere to the cell adhesive regions to create a cell pattern, and are maintained thereafter in a physiologically suitable environment.

Abstract: Provided herein are methods and compositions for the production of hepatocytes from placenta stem cells. Further provided herein is the use of such hepatocytes in the treatment of, and intervention in, for example, trauma, inflammation, and degenerative disorders of the liver. Also provided herein are compositions and methods relating to combinations of nanofibrous scaffolds and adherent placental stem cells and methods of using the same in cartilage repair. Finally, provided herein are compositions and methods relating to nonadherent, CD34+CD45? stem cells from placenta.

Abstract: The present disclosure relates to a preparation of CD140a/PDGFR? positive cells that comprises oligodendrocyte progenitor cells co-expressing OLIG2 and CD140a/PDGFR?. The preparation of cells is derived from pluripotent cells that were derived from skin cells, fibroblasts, umbilical cord blood, peripheral blood, bone marrow, or other somatic cells. The cell preparation has an in vivo myelination efficiency that is equal to or greater than the in vivo myelination efficiency of a preparation of A2B5+/PSA-NCAM? sorted fetal human tissue derived oligodendrocyte progenitor cells. Methods of making, isolating and using the disclosed cell preparation are also described.

Abstract: The present disclosure relates to a preparation of CD140a/PDGFR? positive cells that comprises oligodendrocyte progenitor cells co-expressing OLIG2 and CD140a/PDGFR?. The preparation of cells is derived from pluripotent cells that were derived from skin cells, fibroblasts, umbilical cord blood, peripheral blood, bone marrow, or other somatic cells. The cell preparation has an in vivo myelination efficiency that is equal to or greater than the in vivo myelination efficiency of a preparation of A2B5+/PSA-NCAM? sorted fetal human tissue derived oligodendrocyte progenitor cells. Methods of making, isolating and using the disclosed cell preparation are also described.

Abstract: Methods are described herein for isolating clonal populations of T cells having a defined genetic modification. The methods are performed, at least in part, in a microfluidic device comprising one or more sequestration pens. The methods include the steps of: maintaining individual T cells (or precursors thereof) that have undergone a genomic editing process in corresponding sequestration pens of a microfluidic device; expanding the T cells into respective clonal populations of T cells; detecting, in one or more T cells of each clonal population, the absence of a cell surface marker that was present in the individual T cells (or precursors thereof); and detecting, in one or more T cells of each clonal population, the presence of a first nucleic acid sequence that is indicative of the presence of an on-target genome edit in the clonal population of T cells. Also described are compositions comprising one or more clonal populations of T cells isolated according to the methods disclosed herein.

Abstract: The present invention relates to methods for the specific separation of target cells from a biological sample, comprising specific binding of the target cells to phase-change hydrogel compositions and separation of respective cell-hydrogel complexes by counter-current centrifugation.

Abstract: The present disclosure provides a method for in vitro activation of immune cells for immune cell therapies. The method includes contacting a population of immune cells with ?-glucan to obtain a population of conditioned cells. When introduced into a subject, the population of conditioned immune cells inhibits tumor growth in the subject. A method for inhibiting tumor growth using the population of conditioned immune cells is also provided.

Abstract: Maturation signals provided via cyclic adenosine monophosphate (cAMP)/Exchange proteins activated by cAMP (Epac) signaling during in vitro generation of blood cells from reprogrammed cells or pluripotent stem cells achieve superior function of hematopoietic cells differentiated from stem cells. The cAMP/Epac signaling enables an increased efficiency of production of precursor to blood and to blood cells. These generated blood cells can be utilized for therapeutics, treatments, disease prevention, drug discovery, personalized medicine, regenerative medicine, cell and tissue generation, universal donor banks and related methods and compositions.

Abstract: The present invention relates to a method for preparing lymphoid progenitors. The inventors took advantage of their original and relevant Warts, Hypogammaglobulinemia, Infections and Myelokathexis (WHIM) Syndrome (WS) model and the access to blood samples from five WS patients to investigate the impact of CXCR4 desensitization on BM and extra-medullary (i.e. splenic) hematopoiesis and hematopoietic stem and progenitor cells (HSPCs) recirculation. They developed, for the first time, an original in vitro system permitting to selectively expand HSPCs to obtain lymphoid progenitors by using an original cocktail of cytokines. In particular, the present invention relates to an in vitro method for preparing lymphoid progenitors by culturing HSPCs in an appropriate culture medium comprising an effective amount of a cocktail of cytokines consisting in SCF, IL-3, IL-6, IL-7, Flt-3, and CXCL12.

Abstract: Disclosed are compositions and methods for engineering muscle tissue such as cardiac muscle and skeletal muscle. Tissue engineering platforms use a substrate and a protein micropattern. The protein micropattern forms a plurality of protein lanes and at least one protein bridge that connects adjacent protein lanes having a connection angle is less than 90 degrees. Tissue engineering platforms can promote muscle cell alignment and be used for cell-based pharmacological studies. Also disclosed are degradable substrates for transferring a protein micropattern in the form of a plurality of protein lanes and at least one protein bridge that connects adjacent protein lanes having a connection angle is less than 90 degrees.

Abstract: In related-art methods of differentiating pluripotent stem cells into a desired cell type, there has not been established a differentiation induction method using human ES/iPS cells and being stable and highly efficient. A method of inducing differentiation into a desired cell type within a short period of time and with high efficiency by attenuating differentiation resistance of a pluripotent stem cell to generate a pluripotent stem cell that actively proceeds to a differentiated cell type has been found, and thus the present invention has been completed.

Abstract: The invention relates to progenitor cells of mesodermal lineage and their use in therapy.

Abstract: The present invention provides methods to promote the differentiation of pluripotent stem cells. In particular, the present invention provides an improved method for the formation of pancreatic endoderm, pancreatic hormone expressing cells and pancreatic hormone secreting cells. The present invention also provides methods to promote the differentiation of pluripotent stem cells without the use of a feeder cell layer.

Abstract: Disclosed herein are methods involving the targeting of 5HT biosynthesis in gut insulin-negative cells to convert them into insulin-positive cells. Also, disclosed are methods for treating a disease or disorder in a mammal, preferably a human, associated with impaired pancreatic endocrine function, by administering a therapeutically effective amount of an enumerated active agent that reduces the expression, biosynthesis, signaling or biological activity of serotonin or increases its degradation, wherein administering comprises delivering the agent to Gut Ins? cells in the mammal. Other embodiments of the method are directed to therapy wherein an agent that significantly reduces FOXO1 expression, biosynthesis, signaling or biological activity or increases its degradation is administered in addition to the agent that reduces serotonin, or alternatively an agent that reduces FOXO1 expression is targeted to serotonin-positive gut enteroendocrine cells.