Abstract: An endoscope includes an image pickup apparatus, and the image pickup apparatus includes an imager includes an external electrode, a stacked device, a top electrode on a top surface, and a bottom electrode on a bottom surface, a three-dimensional wiring board having a first zone to which the external electrode is bonded, a second zone to which the top electrode or the bottom electrode is bonded, a third zone to which the top electrode or the bottom electrode is bonded, and a fifth zone arranged on a side surface of the stacked device, wherein the top surface, the bottom surface, and at least two side surfaces of the stacked device are covered with the wiring board.

Abstract: An applicator for positioning a sleeve accessory on a medical speculum, and a method for using the applicator, is provided. The applicator has a flat, oblong shape with a distal end and a proximal end, the proximal end being broader than the distal end. The distal end of the applicator includes a first prong and a second prong. At least a portion of the distal end of the applicator is configured to slide into a lumen of a sleeve accessory to facilitate positioning of the sleeve accessory on a medical speculum.

Abstract: Some implementations of the disclosure are directed to a portable endoscope system. The portable endoscope system may comprise: an endoscope, comprising: a distal end; a proximal end; an endoscope housing integrated into a proximal part of the proximal end; an illumination device housed by the housing; and an endoscope connector to removably couple the endoscope to a first end of a cable connector; and a portable control box separate from the endoscope and to removably couple to the endoscope via the cable connector, the portable control box comprising: a portable control box connector to removably couple the portable control box to a second end of the cable connector; a power source to power the endoscope; a control board to control the endoscope; and a control box housing to house the power source and the control board.

Abstract: The present application discloses a reusable or disposable wireless endoscopic viewing device comprising a wireless transmitter, which can be a microchip transmitter. The reusable wireless endoscopic viewing device also comprises a light source, which can be an L.E.D. light source. The application also discloses a kit having the wireless device. A method for using the reusable wireless endoscopic viewing device is also described and is applicable to any target tissue, bone, joint or target area of the body of a subject.

Abstract: A control for an endoscope includes a housing defining an interior volume. A lever external to the housing extends through the housing into the interior volume. A gear system positioned in the interior volume is operatively coupled to the lever. The gear system includes a first quadrant and a second quadrant each configured to pivot about a corresponding axis to deflect a flexible distal tip portion of the endoscope in a corresponding direction.

Abstract: The invention relates to an endoscope with a shaft, in which at least one working channel is arranged, and with an endoscope head arranged at the distal end of the shaft, wherein a deflection lever is arranged in the endoscope head and is adjustable between a non-deflected starting position and a deflected working position relative to the shaft, and wherein the deflection lever is adjustable via a Bowden wire, the proximal end of which is mounted via a collet on a control handle arranged at the proximal end of the shaft, wherein the collet fixing the proximal end of the Bowden wire is arranged on a slide that is movable proximally out of a housing of the control handle, which slide is coupled to the control handle via a rod. In order to create an endoscope which, having a simple structure, can be easily dismantled, in particular for cleaning purposes, and reassembled, the invention proposes that the slide can be coupled to the rod via a clamping connection.

Abstract: A distal tip of an endoscopic device and a cylindrical cap is disclosed. The distal tip comprises a pattern of alternating grooves and lands on its outer surface. The cylindrical cap is configured to fit tightly over the lands, thereby changing the grooves into closed channels through which liquid or gas can flow.

Abstract: Embodiments of the present invention provide water bottle cap assemblies suitable for attachment to an endoscopic device and a water source. For example, the water bottle cap assembly includes a cap comprising a plurality of ports and an engageable member configured to sealingly engage with a water source. The assembly also includes a plurality of tubular members, each tubular member coupled to a respective port so as to be in fluid communication therewith. In addition, the assembly includes an adaptor coupled to an end of one of the tubular members and configured to couple to an endoscopic device, wherein at least one of the tubular members is configured to convey at least one fluid between the water source and the endoscopic device.

Abstract: An endoscope has an inspection accessory and an operating set. The inspection accessory has a distal end cap, a fastening component, a flexible shaft, an objective optical set, a bending mechanism, and a sheath. The fastening component is connected to the operating set. The flexible shaft is telescopic, flexible, and hollow and has a first end connected to the fastening component and a second end opposite to the first end of the flexible shaft and connected to the distal end cap. The objective optical set is mounted within the distal end cap and the flexible shaft. The bending mechanism is disposed within the flexible shaft and connected to the distal end cap. The sheath is sleeved on the flexible shaft and has two opposite ends respectively tightly connected to the distal end cap and the fastening component.

Abstract: A package is composed of a resin molded body packaging a manipulator of a manipulator system including a base member having a target portion on an upper surface, and the manipulator having a connecting portion detachably connected to the target portion. The package includes a cover portion having a size capable of covering at least a portion of the upper surface of the base member, and a forming portion having easy-cut lines provided in a portion of the cover portion. The forming portion is configured such that by cutting the forming portion along the lines, it is possible to form, at a position corresponding to the target portion when the covering portion is disposed at a position covering the upper surface, an opening portion penetrating a predetermined region including the target portion in the plate thickness direction and wall portions rising upward from an edge of the opening portion.

Abstract: The delivery of biological compounds to ischemic and/or infarcted tissue are described herein where such a system may include a deployment catheter and an attached imaging hood deployable into an expanded configuration. In use, the imaging hood is placed against or adjacent to a region of tissue to be imaged in a body lumen that is normally filled with an opaque bodily fluid such as blood. A translucent or transparent fluid, such as saline, can be pumped into the imaging hood until the fluid displaces any blood, thereby leaving a clear region of tissue to be imaged via an imaging element in the deployment catheter. Additionally, any number of therapeutic tools can also be passed through the deployment catheter and into the imaging hood for performing any number of procedures on the tissue for identifying, locating, and/or accessing ischemic and/or infarcted tissue.

Abstract: An image capturing module is used in an endoscope. The image capturing module comprises an image capturing portion having opposed surfaces defined by respective photodetection and reverse surfaces. The reverse surface includes external electrodes disposed thereon. A layered optical portion having a front surface to which light is applied and a rear surface that is opposite of the front surface. The layered optical portion having a plurality of optical members layered together. A layered device having a first principal surface with joint electrodes disposed thereon. A second principal surface opposes the first principal surface. The first principal surface is bonded to the reverse surface. The joint electrodes are joined to the external electrodes. The layered device includes a plurality of semiconductor devices layered together in which the first principal surface is larger in area than the photodetection surface and smaller in area than the rear surface.

Abstract: An endoscope system includes an endoscope having an insertion portion. The endoscope is attached to the proximal end of the insertion portion. An image capturing module is attached to the distal-end portion of an insertion portion. The image capturing module includes a wiring board having a principal surface including first electrodes and second electrodes disposed thereon. An image capturing element includes respective photodetection and reverse surfaces. The reverse surface includes external electrodes and is connected to the first electrodes on the wiring board. A prism having an entrance surface to which light is applied, a reflection surface, and an exit surface in which the exit surface being bonded to the photodetection surface of the image capturing element. A support member is used to support the prism. A layered element including a plurality of elements is layered together and having an upper surface, a lower surface with element electrodes disposed thereon.

Abstract: A diagnostic tool, such as an otoscope or other hand-held diagnostic device features a handle, a head portion and a circuit. The handle includes a controller and the head portion includes one or more optical spectroscopy (OS) components including at least one light detection element. The circuit includes one or more portions configured to be contorted at acute through reflex angles while maintaining electrical connectivity between the controller and the one or more OS components. The circuit includes a first contact area for the at least one light detection element.

Abstract: A laryngoscope blade (30) includes a blade proximal end (32), to be articulated to a handle (20), a blade distal end (38), a patient tongue side (34), a patient palate side (36), a plurality of adjacent rigid elements (40, 50, 60, 70) extending from the tongue side to the palate side, a plurality of joints (46, 56, 66) articulatedly connecting two of the adjacent rigid elements, and a force-transmitting mechanism (80), with a proximal end (82) and a distal end (87). The force-transmitting mechanism distal end is mechanically connected to the blade distal end. The force-transmitting mechanism is movable relative to the rigid elements in a longitudinal direction. The force-transmitting mechanism proximal end is mechanically couplable to the handle such that, by pivoting of the handle relative to the blade proximal end, the force-transmitting mechanism is moved relative to the blade proximal end.

Abstract: A system and methods for the treatment of amblyopia are described. The system includes a display system capable of in delivering a second image to a second eye of a patient and a first image to a first eye of a patient. The system also includes a controller in capable of delaying the delivery of the second image to the second eye of the patent. The controller is configured to receive the second image and the first image. The controller is also configured to identify a delay factor associated with the second image. The controller is also configured to provide the first image to the display system for viewing by the first eye of the patient. The controller is also configured such that after a delay determined by the delay factor, the controller provides the second image to the display system for viewing by the second eye of the patient.

Abstract: Methods are provided for performing a surgical procedure using optical coherence tomography (OCT) including extracting lenticular material from within a capsular bag of the eye of a patient; placing a replacement lens within the capsular bag after extraction of the lenticular material from the capsular bag; acquiring a plurality of OCT images that visualize the placement of the replacement lens within the capsular bag; and determining from the plurality of OCT images a degree of contact of the posterior surface of the replacement lens with the posterior portion of the capsular bag.

Abstract: A-confocal, interferometric measuring arrangement, a spatially resolving detector, apparatuses for positioning purposes and an evaluation unit. A beam splitter serves to output couple and image on the spatially resolving detector some of the light signal reflected by the cornea, upstream of which detector a reference light source with a delay line and a beam splitter are arranged in order to realize a superposition of the part of the light signal reflected by the cornea, to be imaged on the spatially resolving detector with a reference signal. The evaluation unit is determines the topography of the cornea from the simultaneously recorded signals of the interferometric measuring arrangement and the spatially resolving detector. The proposed solution combines a confocal FD OCT method with elements of imaging holoscopy and can thereby interferometrically measure the topography of the cornea with the necessary accuracy.

Abstract: Disclosed are systems and methods for characterizing corneal shape abnormalities. These methods may be used to differentiate corneas having subclinical keratoconus from other conditions which cause distortion of corneal shape, including warpage of the cornea due to contact lens wear. Also disclosed is classification scheme to aid diagnosis of corneal conditions and thereby guide clinical decision making regarding patient treatment. This classification scheme is based on computed properties of corneal shape, is amenable to automation, and may be implemented in an integrated system or provided in the form of software encoded on a computer-readable medium.

Abstract: A method implemented on a computing device having at least one processor, storage, and a communication platform connected to a network may include: obtaining a head image of a user with one or more dimension indicators, determining an eye region in the head image of the user and determining a pupillary distance of the user based on the one or more dimension indicators and the determined eye region. A method implemented on a computing device having at least one processor, storage, and a communication platform connected to a network may include: receiving a request at a user terminal, recording a video of a user wearing a wearable device with the user terminal, determining a pupillary distance of the user based on the video and synchronously displaying the pupillary distance on the video of the user during recording. The wearable device may include one or more dimension indicators.

Abstract: A fundus camera includes an eyeball-offset detection device and an annular illumination device. The eyeball-offset detection device is configured to detect an offset vector of a lens of the fundus camera relative to an inspected eyeball. The annular illumination device includes a plurality of illumination elements that are arranged in a ring shape around an optical axis of an imaging system of the fundus camera. According to the offset vector of the lens relative to the inspected eyeball, the fundus camera selectively activates one or more illumination elements at corresponding positions to keep an illumination optical path away from a center area of the pupil of the inspected eyeball to reduce effects of corneal reflection and improve illumination quality. Therefore, the abovementioned fundus camera has a large operable range.

Abstract: A wide range within a subject eye is observed while a burden on a subject of whom the subject eye is part is moderated. In an optical system that deals with light reflected from the fundus of the subject eye, a first optical system that pertains to a field of view of a fundus central portion centered on an optical axis is used as a standard optical system. The optical system can be switched by a replacement mechanism from the first optical system to a second optical system that pertains to a field of view of a fundus surroundings portion surrounding the fundus central portion.

Abstract: Both observation of a wide range within a subject eye may be enabled and a burden on a subject of whom the subject eye is part may be moderated. In order of incidence of light from a side at which a pupil of the subject eye is disposed, spreading of the luminous flux is suppressed by a first refracting face, the light is reflected by a first reflection surface with a central aperture, directing the luminous flux in convergent directions in a direction toward the subject eye, the light is reflected in the direction opposite to the direction toward the subject eye by a second reflection surface, and the light is transmitted through the central aperture of the first reflection surface and forms a pupil conjugate image that is conjugate with a position of the pupil of the subject eye.

Abstract: An eye measurement instrument includes: an optical measurement subsystem for measuring an optical characteristic of an eye; an imaging system, including: a camera, an optical system including a movable optical element, and an actuator to move the movable optical element. When the movable optical element is moved into a first position outside an optical path between the eye and the camera, then the optical system focuses a first feature of the eye at the camera, and the camera is configured to capture a first image of the eye, and when the movable element is moved in a second position in the optical path then the optical system focuses a second feature of the eye, different from the first feature, at the camera, and the camera captures a second image of the eye.

Abstract: Methods, apparatus, and systems for medical procedures are disclosed herein and include a monitoring and processing apparatus that includes a memory configured to store a diagnostic algorithm, a sensor configured to sense a patient data of a first patient, a processor configured to generate a first diagnostic result based on the patient data and the diagnostic algorithm. A local computing device is provided and includes a processor and configured to receive the first diagnostic result via a first network, receive a first correction indication that comprises a correction of the first diagnostic result and transmit the first correction indication via a second network. A remote computing device may be provided and be configured to generate an updated diagnostic algorithm that is updated based on the first correction indication and transmit the updated diagnostic algorithm via the second network.

Abstract: A method for detecting biometric parameters includes the steps of performing a bone graft procedure on at least one vertebra of a spine, providing at least one biometric sensor at the at least one vertebra, the sensor measuring at least one parameter selected from the group consisting of pressure, tension, shear, relative position, and vascular flow in an adjacent, surrounding, and measuring the at least one biometric parameter at the vertebra with the sensor.

Abstract: A new generation of precision medicine with interfaces processing the predictive feedback over the course of hyperthermia treatment sessions is provided. Implementation of MR-thermometry measurements and real-time spatial imaging can resolve many of the limiting factors currently associated with hyperthermia treatment. More significantly, implementation of artificial intelligence (machine learning) mediated image analysis and database construction can provide the international community with standards for monitoring, and thermal dose calibration.

Abstract: A reverberant shear wave field in an object such as a patient's body or organ causes deformations in one or more selected directions measured with an imaging modality such as ultrasound or MR equipment or other imaging equipment, to estimate displacements in one or more selected directions over time increments and then viscoelastic properties such as stiffness or other parameters of the ROI.

Abstract: A wearable thermometer patch for monitoring healing of a wound on a user's skin includes a circuit substrate comprising an electric circuit and a plurality of temperature probe units distributed in a two-dimensional array. Each of the plurality of temperature probe units can include a temperature sensor in electric connection with the electric circuit in the circuit substrate. The plurality of temperature probe units can measure temperature values on a user's skin at different positions defined by the two-dimensional array.

Abstract: A smart wearable device includes a detection apparatus and a case, the detection apparatus specifically includes one set of measuring parts and a plurality of sets of light emitting parts; the one set of measuring parts and the plurality of sets of light emitting parts are inlaid into the case and arranged into a polygon, where each of the plurality of sets of light emitting parts and the one set of measuring parts each occupies one of a plurality of angles of the polygon, and a central position of the polygon is at a specified distance to each angle of the polygon. A specific embodiment of the present invention provides a smart wearable device. One set of measuring parts and a plurality of sets of light emitting parts are disposed into a case and arranged into a polygon.

Abstract: A physiological parameter recording system includes a first measurement equipment configured to generate a first physiological parameter, a second measurement equipment configured to generate a second physiological parameter, a recording device installed with a physiological parameter recording program configured to execute the following steps: reading the first physiological parameter by connecting to the first physiological parameter through a digital transmission function, reading the second physiological parameter by a user input interface, displaying the first and second physiological parameters, confirming and storing the first and second physiological parameters after the user input interface has been locked according to a lock signal, and generating and displaying a quick response code according to the first and second physiological parameters, and a cloud database configured to receive the quick response code from the recording device through the digital transmission function.

Abstract: A wearable assembly has a pulse plethysmography (PPG) sensor and a piezoelectric pressure sensor and is attachable to a patient's finger or other area corresponding to a peripheralvascular region, and further includes a signal processor configured to monitor blood flow dependent measurements and pressure measurements over time, comparing these measurements to determine properties of the vascular region, such as vascular resistance of a blood vessel, vascular radius of the blood vessel, vascular stiffness of the vascular region, blood pressure, and/or cardiac vascular power. The signal processor may apply a hysteresis comparison of the sensor outputs, e.g., using an elliptical model, and in some examples may apply an extended Kalman filter for optimizing output of the vascular region properties.

Abstract: Pulse waves of a living body are detected with high accuracy. A pulse wave detection device includes a camera configured to capture an image of the living body a plurality of times through a first green filter and an infrared light filter having light transmission characteristics in a near-infrared light wavelength range within a wavelength range where a light absorption coefficient of oxidized hemoglobin is greater than a light absorption coefficient of reduced hemoglobin, and an image analysis unit configured to analyze a plurality of images of the living body captured by the camera and to detect the pulse waves of the living body. The image analysis unit is configured to detect the pulse waves by detecting a change in intensity of light in the near-infrared light wavelength range indicated by the plurality of images.

Abstract: An apparatus for non-invasively estimating blood pressure is provided. Thee apparatus for estimating blood pressure may include a bio-signal measurer configured to measure a bio-signal from a user and a processor configured to estimate blood pressure using the measured bio-signal. The processor may extract a first feature and a second feature from the bio-signal at an extraction time, estimate changes in the first feature and the second feature which have occurred during a time period from a calibration time at which the first feature and the second feature are calibrated to the extraction time at which the first feature and the second feature are extracted, and estimate a blood pressure based on the changes in the first feature and the second feature.

Abstract: Intravascular devices, systems, and methods are disclosed. In some embodiments, the intravascular devices include at least one pressure sensing component within a distal portion of the device. In that regard, one or more electrical, electronic, optical, and/or electro-optical pressure-sensing components is secured to an elongated member and the system includes components to process the output signals according to various calibration parameters.

Abstract: A blood flow measurement system for measuring a blood flow quantity such as flow velocity or flow volume inside a blood vessel includes an intravascular blood flow measurement device with a body that comprises an expandable body section. A control unit sequentially provides a size control signal indicative of a respective one of the at least two predetermined expandable sizes to be assumed by the expandable body section. A pressure sensor unit measures respective sequences of blood pressure signals over a measuring time span defined with respect to a heart cycle period. A flow determination unit uses the values of cross sectional area of the expandable body section, the associated pressure signals and a known value of a density of blood, to calculate a value of a blood flow quantity inside the blood vessel based on Bernoulli's law.

Abstract: Disclosed is a heart rhythm monitoring apparatus, including a water-proof case, a water-proof patch, at least two electrodes, a battery, and an electric circuit. The water-proof case is attached to the water-proof patch to form a water-proof space for accommodating the battery and the electric circuit. Each electrode is connected to the electric circuit, and outwards extends from the water-proof space to form a sensing end. The electrodes penetrate the water-proof patch and the water-proof patch and the sensing ends contact an animal skin. The water-proof patch provides adhesion, and the sensing ends are configured to sense electrical signal on the animal skin. The electrical signal is processed by the electric circuit, and the corresponding heart rhythm information is acquired and recorded. The present invention provides water-proof feature and possesses a simple structure, thereby improving convenience of use, prolonging operation period, acquiring a long-term record of heart rhythm information.

Abstract: An invasive instrument (1) is disclosed comprising an instrument tip including a sensor chip (10) comprising a sensor (20) adapted to produce a modulated sensor signal having a signal frequency and a non-volatile memory (30) responsive to said sensor signal for storing data relating to said sensor; a first supply wire (11) for connecting the sensor chip to ground and a second supply wire (13) for connecting the sensor chip to a power supply (61) for providing a supply voltage to the sensor chip. The device further comprises a circuitry arrangement arranged to combine said sensor signal and said output into a combined signal and superimpose said combined signal as a modulation over the supply voltage such that simultaneous data communication of the sensor and memory data can be provided using two interface wires only. A system including such an invasive instrument and a method of operating such a system are also disclosed.

Abstract: The subject matter of the present disclosure generally relates to techniques for neuromodulation of a tissue that include applying energy (e.g., ultrasound energy) into the tissue to cause altered activity at a synapse between a neuron and a non-neuronal cell.

Abstract: Neural interfaces with the peripheral nervous system have been developed to provide a direct communication pathway between peripheral nerves and prosthetic limbs. Described herein is a microchannel integrated neural network device and system which can control the reinnervated muscles and interpret neurological signals. The acquired bioelectrical signals can be used for the interpretation of mind and create a neural map.

Abstract: A medical patch includes a substrate, an electrode, and circuitry. The substrate is configured to attach externally to a patient. The electrode is coupled to the substrate and is configured to sense electrocardiogram (ECG) signals from a heart of the patient, and to further sense electrical signals indicative of an impedance between the electrode and a probe in the heart. The circuitry is coupled to the substrate and includes a shared amplifier that is configured to simultaneously amplify the ECG signals and the electrical signals sensed by the electrode.

Abstract: An analyzing method is to be implemented in an analyzing device, and includes: (A) dividing respective cycle lengths of a plurality of cardiac cycles of a user during sleep into a plurality of groups based on an order of occurrence of the cardiac cycles; (B) for each group, performing Fourier transform on the cycle lengths of the group to generate a respective spectrum; (C) for each group, calculating total power of the respective spectrum; and (D) determining, for each group, whether sleep quality of the user in a time period during which the corresponding cardiac cycles occurred is poor based on the total power of the respective spectrum and a predetermined threshold.

Abstract: The present disclosure facilitates the evaluation of wide-band phase gradient information of the heart tissue to assess, e.g., the presence of heart ischemic heart disease. Notably, the present disclosure provides an improved and efficient method to identify and risk stratify coronary stenosis of the heart using a high resolution and wide-band cardiac gradient obtained from the patient. The patient data are derived from the cardiac gradient waveforms across one or more leads, in some embodiments, resulting in high-dimensional data and long cardiac gradient records that exhibit complex nonlinear variability. Space-time analysis, via numeric wavelet operators, is used to study the morphology of the cardiac gradient data as a phase space dataset by extracting dynamical and geometrical properties from the phase space dataset.

Abstract: The disclosure relates to a method for determining a plurality of action potentials in the heart having the following steps: a) Recording a surface ECG signal synchronously with at least 64 channels, b) Recording at least one IEGM signal, c) Processing the surface ECG signal by means of ICA analysis and determining the sum and position of a plurality of action potentials in the heart based on the ICA analysis, and, d) Comparing the at least one IEGM signal to the plurality of action potentials and correcting the sum and/or position of at least one of the plurality of action potentials in the heart based on this comparison. The disclosure further relates to a corresponding device, a corresponding computer program product, and a corresponding system.

Abstract: The present disclosure relates to a method for controlling a magnetic resonance imaging guided radiation therapy apparatus (100) comprising a magnetic resonance imaging system (106). The method comprises: acquiring magnetic resonance data using the magnetic resonance imaging system from an organ (146), the organ being marked by a predefined marker; the magnetic resonance data comprising 3D image data; identifying in a reconstructed 2D image of the magnetic resonance data at least one signal void candidate of the marker; processing the 3D image data and the identified signal void for calculating a likelihood that the identified signal void candidate is part of the marker; outputting an indication of the calculated likelihood; in response to the outputting, receiving a user input specifying performing a radio therapy; and controlling the irradiation of the organ using the radiation therapy.

Abstract: An MRI image processing and analysis system may identify instances of structure in MRI flow data, e.g., coherency, derive contours and/or clinical markers based on the identified structures. The system may be remotely located from one or more MRI acquisition systems, and perform: perform error detection and/or correction on MRI data sets (e.g., phase error correction, phase aliasing, signal unwrapping, and/or on other artifacts); segmentation; visualization of flow (e.g., velocity, arterial versus venous flow, shunts) superimposed on anatomical structure, quantification; verification; and/or generation of patient specific 4-D flow protocols. An asynchronous command and imaging pipeline allows remote image processing and analysis in a timely and secure manner even with complicated or large 4-D flow MRI data sets.

Abstract: A security check method includes: pre-creating at least four concurrently operating threads, one thread being responsible for movement control and data acquisition, one thread being responsible for imaging processing, one thread being responsible for interface displaying, and one thread being responsible for target detection and recognition; then the four concurrently operating threads divide original echo data of a human body to be checked into data of a plurality of adjacent overlapped azimuthal segments during data processing and perform individual processing on the data of each azimuthal segment. The security check system includes a thread creating unit, a first thread parallel unit, a second thread parallel unit, a third thread parallel unit, a fourth thread parallel unit, and a thread loop control unit. Because subsequent data processing is not required to be performed after the acquisition of all data is completed, the time for a security check process is reduced.

Abstract: The goal of the present invention is to calculate with high accuracy a numerical value representing skin barrier function in a wide range of skin conditions. Provided is an operation processing apparatus calculates a first variable based on delay time measured using an alternating-current (AC) signal generated by the AC signal generation circuit and a signal applied by an application electrode and passing through skin and stores the first variable calculated by the processor as a calculation result. The operation processing apparatus calculates a numerical value representing the skin barrier function based on the calculation result.

Abstract: Devices, systems, and methods for non-invasively detecting and monitoring medical conditions using multiple modalities of sensing include at least two electrodes configured to be positioned on a subject, an acoustic sensor configured to be positioned on a subject, a thoracic impedance measurement module connected to the electrodes, for measuring a first impedance between the electrodes, and a heart acoustic measurement module connected to the acoustic sensor, for detecting and measuring a heart sound from the acoustic sensor.

Abstract: A three-dimensional tomograph as can be used for examining and manipulating objects on the millimeter scale or smaller, for example, for examining and manipulating biological cells, molecules or ions. The three-dimensional tomograph achieves reproducible and reliable signals in millimeter dimensions or smaller dimensions without significant signal overlays. The three-dimensional tomograph is composed of at least one three-dimensional microcomponent made of a rolled-up or folded-up layer stack of at least one carrier layer and electrodes at least located thereon for the impedance measurement. The electrodes for the impedance measurement are once or repeatedly arranged essentially on the inner or outer surface of the microcomponent in a fully surrounding manner on at least one plane, and the measurement object is located in the interior of the microcomponent and/or around the microcomponent.