Abstract: Certain embodiments pertain to pupil ptychography methods and systems.

Abstract: An ophthalmologic imaging apparatus includes a housing configured to include an optical system that irradiates a subject's eye with measurement light and receives returning light returned from the subject's eye irradiated with the measurement light, a rotation unit configured to rotate the housing by making a predetermined position on an optical axis of the optical system as a rotation center, a position changing unit configured to change a position of the rotation center on the optical axis of the optical system, and a holding unit configured to hold a positional relationship between the housing and the subject's eye when the position of the rotation center on the optical axis of the optical system is changed.

Abstract: A medical device system includes a first medical device and a second medical device. The first medical devices includes a first measuring unit that acquires measurement data of vital signs of a patient and a first communication unit that transmits the measurement data acquired by the first measuring unit to the second medical device. The second medical device includes a second communication unit that receives the measurement data from the first communication unit. The first and second medical devices are configured so that if certification processing succeeds, the measurement data is permitted to be used in the second medical device.

Abstract: The present disclosure relates to techniques for receiving glucose data from a continuous glucose sensor and controlling the use and redistribution of that data so it is used in an intended manner. In one aspect, a method includes obtaining one or more data points relating to glucose levels from a transmitter associated with a continuous glucose monitor device; distributing the one or more data points among one or more display devices and one or more servers; identifying a missing data point from among a display device of the one or more display devices or a server of the one or more servers, the missing data point being one of the one or more data points; and providing the missing data point to the display device or the server when the missing data point falls within a defined time period.

Abstract: A handheld diabetes management device for managing blood glucose test data and continuous glucose monitoring data includes a port configured to receive a test strip, a wireless transceiver, a communications processor, and a user interface processor. The communications processor communicates with the wireless transceiver to periodically collect glucose measurement data from a continuous glucose monitoring device and to store the glucose measurement data in a first data storage module. The communications processor is operable to consume electrical power at a first rate. The user interface processor communicates with the communication processor to receive the glucose measurement data and operable to display the glucose measurement data on the device. The communications processor operates asynchronously from operation of the user interface processor to collect the glucose measurement data and the user interface processor operates to consume electrical power at a second rate that is higher than the first rate.

Abstract: A control method of an information terminal causes a display to display a display screen which includes a first display region and a second display region. The first display region displays an object medical image. The second display region displays M number of similar medical images and includes ND number of individual regions for displaying the M number of the similar medical images. When an instruction from one or more instruction buttons is detected, a display size of each corresponding region of interest that is included in the second number of the similar medical images is changed while maintaining a size of each of the individual regions in the second display region, and each of the similar medical images is magnified at a magnification ratio of a reference thumbnail.

Abstract: A medical system and method of communicating between a telemetry controller and a plurality of medical devices implanted within a patient is provided. Communication links are respectively established between the telemetry controller and the implanted medical devices. The communication links are respectively amplitude modulated by the implanted medical devices at modulation levels using load modulation. Received signal strength indicators (RSSIs) of the amplitude modulated communication links for the implanted medical devices are measured. A variation of the RSSIs is decreased by modifying, based on the measured RSSIs, at least one modulation level at which the respective at least one communication link is amplitude modulated by the respective implanted medical device(s).

Abstract: Embodiments of the present disclosure include a photodiode that can detect optical radiation at a broad range of wavelengths. The photodiode can be used as a detector of a non-invasive sensor, which can be used for measuring physiological parameters of a monitored patient. The photodiode can be part of an integrated semiconductor structure that generates a detector signal responsive to optical radiation at both visible and infrared wavelengths incident on the photodiode. The photodiode can include a layer that forms part of an external surface of the photodiode, which is disposed to receive the optical radiation incident on the photodiode and pass the optical radiation to one or more other layers of the photodiode.

Abstract: An OCT apparatus and method for characterization of a fluid adjacent to a tympanic membrane has a low coherence source which is coupled to a splitter which has a measurement path and a reference path. The reference path is temporally modulated for length, and the combined signals from the reference path and the measurement path are applied to a detector. The detector examines the width of the response and the time variation when an optional excitation source is applied to the tympanic membrane, the width of the response and the time variation forming a metric indicating the viscosity of a fluid adjacent to the tympanic membrane being measured.

Abstract: A method for measuring the activity of one or more excitable cells, such as neurons, in a target tissue is provided. The present method may include measuring the activity of individual, selected excitable cells by projecting one or more three dimensional (3D) multi-focal laser light patterns into a target tissue containing excitable cells adapted to emit cellular electrical activity—sensitive fluorescence, to generate a multiplexed 2D diffraction pattern of fluorescence emitted by the neurons, and resolving the multiplexed 2D diffraction pattern. Also provided herein is a system configured to perform the present method, the system including a microscope configured to project one or more 3D multi-focal laser light patterns into a target tissue using a spatial light modulator and a mirror galvanometer, and a microlens array and an image detector to record individual and multiplexed 2D diffraction patterns of light emitted from the target tissue.

Abstract: Multispectral images, including ultraviolet light and its interactions with ultraviolet light-interactive compounds, can be captured, processed, and represented to a user. Ultraviolet-light related information can be conveniently provided to a user to allow the user to have awareness of UV characteristics and the user's risk to UV exposure.

Abstract: A laser based vascular illumination system utilizing a FPGA for detecting vascular positions, processing an image of such vasculature positions, and projecting the image thereof onto the body of a patient.

Abstract: The present disclosure relates to a terahertz imaging system for imaging a lumen of a human, such as an intravascular space. A system may include a catheter and a terahertz transceiver device coupled to the catheter. The terahertz transceiver device may be operative to output terahertz radiation through a lumen of a human and to receive reflection signals based on the terahertz radiation. A power source may be coupled to the terahertz transceiver device. The system may further include a controller in communication with the terahertz transceiver device. The controller is operative to obtain an image of the lumen based on the reflection signals.

Abstract: A catheter system for optical coherence tomography includes an elongate catheter body, an optical fiber in the elongate catheter body, and an anamorphic lens assembly coupled with a distal end of the optical fiber. The optical fiber and the lens assembly are together configured to provide a common path for optical radiation reflected from a target and from a reference interface between the distal end of the optical fiber and the lens assembly.

Abstract: An optical probe having a controlled viewing angle lens tip is provided that includes an elastomer lumen, where the elastomer lumen includes internal dividers disposed to separate the elastomer lumen into a plurality of channels, a lens that is sealably attached to a distal end of the elastomer lumen, where each channel is disposed to operate as an independent hydraulic channel, where an angle of the lens relative to a central axis of the elastomer lumen is positioned according to a state of pressure in each independent hydraulic channel, and a hydraulic generator, where the hydraulic generator is disposed to pressurize each hydraulic channel to a defined state as set by a computer input from a to computer.

Abstract: A surgical vision system for imaging heat capacity and cooling rate of tissue has an infrared source configured to provide infrared light to tissue, the infrared light sufficient to heat tissue, and an infrared camera configured to provide images of tissue at infrared wavelengths. The system also has an image processing system configured to determine, from the infrared images of tissue, a cooling or heating rate at pixels of the images of tissue at infrared wavelengths and to display images derived from the cooling rate at the pixels.

Abstract: A heat monitoring instrument of the invention includes: an insertion portion for inserting into tissue of a subject; a distal end portion that constitutes a distal end portion of the insertion portion and receives and transmits heat of the subject into which the insertion portion is inserted; and a shape-memory portion that constitutes the distal end portion and changes shape due to the heat of the subject.

Abstract: A method and apparatus including a computing device to quantify a term of a service agreement in a context of a proposed solution, evaluate solution characteristics against a given gateway architecture, and compare the solution characteristics to desired service-agreement solution metrics. The solution characteristics include simulated observed characteristics.

Abstract: In one embodiment, a method for creating a blood oxygen saturation (SpO2) value, the method comprises receiving one or more photoplethysmography (PPG) signals for SpO2 detection from one or more PPG sensors; receiving one or more PPG signals for characterizing a heart rate from the one or more PPG sensors; using the one or more PPG signals for SpO2 detection, forming one or more SpO2 datasets wherein the SpO2 datasets respectively comprise one or more noise components; removing the one or more noise components from the one or more SpO2 datasets that are inconsistent with a feature of the one or more PPG signals characterizing the heart rate to produce one or more filtered SpO2 datasets; and using the one or more filtered SpO2 datasets, creating and storing the SpO2.

Abstract: A combined physiological sensor and methods for detecting one or more physiological characteristics of a subject are provided. The combined sensor (e.g., a forehead sensor) may be used to detect and/or calculate at least one of a pulse blood oxygen saturation level, a regional blood oxygen saturation level, a respiration rate, blood pressure, an electrical physiological signal (EPS), a pulse transit time (PTT), body temperature associated with the subject, a depth of consciousness (DOC) measurement, any other suitable physiological parameter, and any suitable combination thereof. The combined sensor may include a variety of individual sensors, such as electrodes, optical detectors, optical emitters, temperature sensors, and/or other suitable sensors. The sensors may be advantageously positioned in accordance with a number of different geometries.

Abstract: A method of monitoring a blood pressure includes: emitting a laser to a blood vessel in a body part; detecting, from the body part, laser speckles caused by scattering of the emitted laser; obtaining a bio-signal indicating a change in a volume of the blood vessel by using the detected laser speckles; and estimating a blood pressure based on the obtained bio-signal.

Abstract: A blood pressure detection method is used for the sphygmomanometer including an envelope, an air pressure control mechanism, an ultrasonic wave transmission mechanism and an ultrasonic wave reception mechanism. The blood pressure detection method includes: applying a control signal to the air pressure control mechanism and the ultrasonic wave transmission mechanism, to inflate and deflate the envelope, and enable the ultrasonic wave transmission mechanism to transmit an ultrasonic detection signal toward the to-be-detected body part at a predetermined interval; monitoring an ultrasonic reflection signal received by the ultrasonic wave reception mechanism; determining a detection time point for the blood pressure detection in accordance with a frequency of the ultrasonic reflection signal during the deflation of the envelope; and determining a blood pressure value for the blood pressure detection in accordance with a pressure value of air within the envelope at the detection time point.

Abstract: A flow rate control valve includes a bobbin and a plunger. On an inner circumferential surface of the bobbin, multiple protruding regions that extend in a direction parallel in an axial direction to the plunger, and a plurality of recessed grooves that form flow paths for a fluid when valve is open are provided side by side alternatingly in a circumferential direction. The multiple recessed grooves include a first recessed groove, second recessed groove, and third recessed groove that are arranged side by side sequentially in the circumferential direction. An interval in the circumferential direction between the first recessed groove and second recessed groove and an interval in the circumferential direction between the second recessed groove and third recessed groove are the same. Surfaces of the multiple protruding regions formed on the inner circumferential surface of the bobbin can be arranged at positions closer to those of one perfect circle.

Abstract: Described is an apparatus which comprises: a source to generate a first current having AC and DC components; a current-to-voltage converter to convert the first current or a copy of the first current to a first voltage proportional to a resistance, the first voltage having AC and DC components that correspond to the AC and DC components of the first current; a sample-and-hold circuit to filter the AC component from the first voltage and for providing an output voltage with the DC component; and an amplifier to receive the output voltage.

Abstract: A method for dual-contrast unenhanced magnetic resonance angiography includes iteratively acquiring flow-dependent slices and flow-independent slices in a region. Each iteration of the acquisition process comprises identifying a flow-dependent slice location within the region and identifying a flow-independent slice location upstream from the flow-dependent slice location according to blood flow in the region. Each iteration further includes applying a first radio frequency (RF) saturation pulse to the region such that MR signals from veins in the region are substantially suppressed, and applying a second RF saturation pulse to the flow-dependent slice location such that MR signals from background muscle and arterial blood in the region are substantially suppressed. A flow independent slice is acquired at the flow-independent slice location after the second RF saturation pulse is applied and before unsaturated arterial blood has maximally flowed into the region.

Abstract: A method includes accepting from a medical imaging system a plurality of map points, each map point including a respective coordinate on a surface of a body organ measured by bringing a medical probe into proximity with the surface. An operator input, which specifies a spatial density at which the map points are to be displayed, is accepted. A subset of the map points is selected responsively to the operator input. The surface is visualized at the specified spatial density by displaying the selected subset of the map points.

Abstract: The present disclosure generally relates to user interfaces for health monitoring. Exemplary user interfaces for initial setup of health monitoring using a first electronic device and a second electronic device is described. Exemplary user interfaces for recording biometric information for use in health monitoring is described. Exemplary user interfaces for using an input device while recording biometric information for health monitoring is described. Exemplary user interfaces for viewing and managing aspects of health monitoring is described.

Abstract: A system for recording intracardiac signals and for providing stimulation pulses and/or ablation energy at intracardiac locations. The system includes intracardiac terminals adapted to collecting intracardiac electrophysiological potentials from respective intracardiac locations in an individual; an indifferent terminal adapted to collecting indifferent electro-physiological potentials from the individual; a differential amplifier stage adapted to receiving and amplifying the electrophysiological potentials collected from the intra-cardiac and indifferent terminals with respect to a signal reference to obtain respective intracardiac and indifferent signals; a processor device adapted to determining a common mode signal as an average of the intracardiac and indifferent signals and adapted to providing an output of intracardiac data based at least on the intracardiac signals, wherein the intracardiac signals are referenced with respect to the common mode signal.

Abstract: A surgical guidance system has two cameras to provide stereo image stream of a surgical field; and a stereo viewer. The system has a 3D surface extraction module that generates a first 3D model of the surgical field from the stereo image streams; a registration module for co-registering annotating data with the first 3D model; and a stereo image enhancer for graphically overlaying at least part of the annotating data onto the stereo image stream to form an enhanced stereo image stream for display, where the enhanced stereo stream enhances a surgeon's perception of the surgical field. The registration module has an alignment refiner to adjust registration of the annotating data with the 3D model based upon matching of features within the 3D model and features within the annotating data; and in an embodiment, a deformation modeler to deform the annotating data based upon a determined tissue deformation.

Abstract: Disclosed are an electronic device and operating method thereof. The present invention includes recognizing an electrode initially in contact with the user's body part among a plurality of electrodes as a first pair, recognizing the rest of the electrodes contacted with the user's body as a second pair, measuring a current flowing between the recognized first and second pairs, determining a biometric information of the user based on the measured current and load, and outputting the determined biometric information.

Abstract: The present invention provides an apparatus and a corresponding method useful for electron paramagnetic resonance imaging, in situ and in vivo, using high-isolation transmit/receive (TX/RX) coils, which, in some embodiments, provide microenvironmental images that are representative of particular internal structures in the human body and spatially resolved images of tissue/cell protein signals responding to conditions (such as hypoxia) that show the temporal sequence of certain biological processes, and, in some embodiments, that distinguish malignant tissue from healthy tissue. In some embodiments, the TX/RX coils are in a surface, volume or surface-volume configuration.

Abstract: Systems and method for positioning a neonate within an imaging device are provided. A capsule incubator, a cart, and a docking incubator are used to move a baby between an imaging device and a incubator, such that a baby can be imagined without having to move the baby from its environment.

Abstract: A catheter system includes an elongate flexible catheter and a support structure mounted on a proximal portion of the elongate flexible catheter. The support structure includes a first alignment feature configured to mate with a first sensor such that the first sensor is maintained parallel to a longitudinal axis of the support structure, and a second alignment feature configured to mate with a second sensor such that the second sensor is maintained parallel to the longitudinal axis of the support structure and such that the second sensor is fixed relative to the first sensor in at least one degree of freedom.

Abstract: An example method includes applying a localization signal to a source electrode positioned within a conductive volume and a ground electrode at a known location. Electrical activity is sensed at a plurality of sensor electrodes distributed across an outer surface of the conductive volume. The locations of each of the sensor electrodes and the location of the ground electrode being stored in memory as part of geometry data. The electrical activity sensed at each of the sensor electrodes is stored in the memory as electrical measurement data. The method also includes computing a location of the source electrode by minimizing a difference between respective pairs of source voltages determined for the plurality of sensor electrodes. The source voltage for each of the sensor electrodes is determined based on the electrical measurement data and the geometry data.

Abstract: Methods and systems are disclosed for the detecting of whether a subject has a lung disorder such as asthma, tuberculosis or lung cancer. Monitoring the subject's health and prognosis is also disclosed.

Abstract: Described herein are example methods, devices and systems for motion compensation in ultrasonic respiration monitoring. A respiration detection system includes a first probe placed on a front side of a patient's body and a second probe placed on a dorsal side of the body. The first probe includes an ultrasound transducer, a first accelerometer unit and a magnetic field sensor unit, and the second probe includes a second accelerometer unit and magnetic field sensor unit. Due to respiration of the patient, the abdominal region of the body moves, creating measurement errors when an ultrasound beam is directed towards an internal structure (internal tissue region) inside the patient's body. Correction for such measurement errors uses input data from the first and second accelerometer units and the magnetic field sensor unit.

Abstract: The present application discloses a method and apparatus for testing vital capacity. The method comprises: measuring a static pressure P0 of a pressure hole inner cavity of a mobile device; wherein the pressure hole is communication with the exterior and is purposely disposed on the mobile device or is an already-designed opening; obtaining an air pressure P(t) at each moment by blowing air towards the pressure hole; obtaining an air flow speed v(t) corresponding to each moment according to a correspondence relation formula between the air flow speed v(t) and a pressure differential P(t)?P0; and obtaining vital capacity Vc of the subject according to a correspondence relationship between a measurement time t and the air flow speed v(t).

Abstract: The development and manufacture of thermal interface materials including, among other forms, greases, pastes, gels, adhesives, pads, sheets, solders and phase change materials, with good through-plane thermal conductivity for thermal interface applications. The good through-plane thermal conductivity is achieved through the formation of a conductive network by the use of thermal conductive material-coated fillers, combinations of thermal conductive material-coated fillers and uncoated fillers.

Abstract: A color or shade assessment system and a method of assessing color or shade of an object. The system may include a color or shade measurement device having a probe portion terminating at a distal end, a light emitter assembly, and a light receiver assembly. Furthermore, a spacer including a sleeve extending from a proximal end to a distal end and defining a passageway may be coupled to the probe portion. The spacer may be alterable between (1) a first state in which the spacer is detached from the probe portion; and (2) a second state in which at least a portion of the probe portion extends into the central passageway of the sleeve and the distal end of the probe portion is located between the proximal and distal ends of the sleeve.

Abstract: Devices and methods for sizing valve apertures and luminal organs. In at least one embodiment of a device for obtaining measurements within a luminal organ of the present disclosure, the device comprises an elongated body, and at least one sizing finger positioned at a distal end of the elongated body, the at least one sizing finger configured to move from a first position to a second position by way of adjustment of at least one movable device coupled thereto, wherein a dimensional measurement within the luminal organ can be determined based upon the first position and the second position.

Abstract: This disclosure describes a multifunctional assessment system that can include a seating platform (e.g., chair, bench, or the like) for a subject, an image-capturing device, and one or more sensors directly or indirectly coupled to the seating platform. The image-capturing device (e.g., camera or motion sensor) records ambulatory motion of the subject, and the one or more sensors can detect at least one of a force or a motion of the subject, such as a seating motion, posture, weight distribution, and motions or forces associated with the subjects overall health. For example, motions or forces detected can be associated with a subject's ability to get up off the seating platform, sit upright, grip strength, and so forth.

Abstract: A portable telemetry device includes a physiological component, a fall detector component, a radio, and a communication component. The physiological component is configured to receive, from at least one sensor, physiological data representative of a physiological condition of a patient. The fall detector component is configured to detect a fall of the portable telemetry device. The radio is configured to wirelessly send radio signals. The communication component is configured to transmit the physiological data and an indication of the fall to a monitoring system using the radio.

Abstract: The invention relates to wearable electronic devices for monitoring physical activities of a person. The invention also concerns related methods and computer program products. According to the invention, a first sensor for measuring acceleration data and a second sensor for measuring heart rate data is provided. A data processing unit is configured to operate in a first mode when data is read from said first and second sensors and in a second mode when data is not read from at least one of said first and second sensors. In the first operating mode the processing unit cumulatively computes and updates a heart rate offset value based on at least one of the following data: a predetermined pulse of the person a rest, a predetermined fitness level of the person, a current recovery pulse of the person, and/or the cumulated acceleration data during the current activity. It also computes a current activity gain value based on acceleration data and heart beat rate data.

Abstract: Apparatus is disclosed for monitoring, measuring and/or estimating a force applied to a body or body part of a vertebral mammal. The apparatus includes an acceleration sensor for measuring acceleration of the body or body part relative to an inertial frame of reference and for providing data indicative of the acceleration. The acceleration sensor includes at least one inertial sensor, a memory device adapted for storing the data, and a processor adapted for processing the data to evaluate a reaction force that correlates to the data. The processor may be configured to execute an algorithm for evaluating the reaction force, based on one or more correlation components such as mass, speed and/or velocity associated with the body or body part. A method of monitoring and/or estimating a force applied to a body or body part of a vertebral mammal is also disclosed.

Abstract: A hearing diagnosis device and a hearing diagnosis method are provided. The device includes a storage unit, an otoacoustic emission detecting module, and a hearing diagnosis management module. The storage unit stores a hearing diagnosis image sample database and a hearing information sample database. The otoacoustic emission detecting module is configured to perform an otoacoustic emission detecting operation by playing a test audio to an ear of a user to obtain a first hearing diagnosis image corresponding to the ear. The hearing diagnosis management module is configured to perform a hearing diagnosis operation according to the first hearing diagnosis image, a plurality of hearing diagnosis image samples of the hearing diagnosis image sample database, and a plurality of hearing information samples, respectively corresponding to the hearing diagnosis image samples, of the hearing information sample database, so as to determine first hearing information of the ear.

Abstract: Methods and apparatus are provided for communication among display devices and sensor electronics unit in an analyte monitoring system. The analyte monitoring system may include a sensor that is configured to perform measurements indicative of analyte levels. The sensor may be communicatively coupled to the sensor electronics unit. The sensor electronics unit may be configured to transmit data indicative of analyte levels to the display devices using one or more communication protocols. Furthermore, the sensor electronics unit may be configured to operate in multiple modes, and switch between the modes in response to commands received from the display devices. Related systems, methods, and articles of manufacture are also described.

Abstract: A reusable sensor is disclosed for producing a signal indicative of at least one physiological parameter of tissue. The sensor can include a sensor housing that has a distal opening, a wire lumen, and a proximal opening. The distal opening can include a lumen extending through the body of the sensor housing and the wire lumen can be located on the outside of the sensor housing. The sensor can also include a first component located on a top surface of the sensor housing and along the pathway of the wire lumen. The sensor can also include a second component located on the bottom surface of the sensor housing opposite of the first component. The second component can also be located along the pathway of the wire lumen. The sensor can also include a wire coaxially disposed within the wire lumen and connecting the first component and second component.

Abstract: A blood collection tube holder embodying two coaxially alignable needles, the first needle being a forwardly facing venipuncture needle and the second needle being a rearwardly facing fluid discharge needle. The first and second needles are satisfactorily supported by a frontal attachment and body, respectively, that are disposed in relative sliding engagement along an interface that is transverse to the first and second needle and that extends at least from the second needle to an opening into a needle retraction chamber that projects rearwardly from the body. The subject device is configured to receive and support a conventional blood collection tube of the type used to collect blood samples.

Abstract: A fluid handling module that is removably engageable with a bodily fluid analyzer is provided. The module may comprise a fluid handling element, and a fluid component separator that is accessible via the fluid handling element and configured to separate at least one component of a bodily fluid transported to the fluid component separator. The fluid handling element may have at least one control element interface.

Abstract: Disclosed is an apparatus for analyzing the composition of bodily fluid. The apparatus can include a fluid handling network including a patient end configured to maintain fluid communication with a bodily fluid in a patient and a pump unit in operative engagement with the fluid handling network. The pump unit can have an infusion mode, in which the pump unit is operable to deliver infusion fluid to the patient through the patient end, and a sample draw mode, in which the pump unit is operable to draw a sample of the bodily fluid from the patient through the patient end. The apparatus can include a spectroscopic analyzer positioned to analyze at least a portion of the sample; a processor in communication with or incorporated into the spectroscopic analyzer; and stored program instructions executable by the processor to obtain measurements of two or more properties of the sample.