Patents Issued in March 17, 2020
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Patent number: 10590022Abstract: Apparatus and method for producing elongated glass components with low bow. The apparatus may include a heating element to heat a bulk glass component where a strand may be drawn from the bulk glass component in a downward direction and a gripper device including a clamping element to support the strand while pulling or drawing it from the bulk glass component in a linear motion, and a low-friction mounting element attached to the clamping element which allows translational movement of the clamping element in an x-y plane. The gripper device may further be used to reduce bow in the strand while it is being drawn by moving the clamping element on the mounting element in a direction opposite the direction of any measured transverse acceleration.Type: GrantFiled: January 22, 2015Date of Patent: March 17, 2020Assignees: HERAEUS QUARTZ NORTH AMERICA LLC, HERAEUS QUARZGLAS GMBH & CO. KGInventors: Georges Levon Fattal, James E. Beavers, Jr., Oliver Ganz, Kai Huei Chang
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Patent number: 10590023Abstract: Glass flakes according to the present invention include: glass flake substrates; and a coating covering at least a portion of a surface of each of the glass flake substrates and composed of a binder. The binder includes a bismaleimide compound, a resin, and a silane coupling agent as essential components and includes a peroxide as an optional component. The proportion of the peroxide in the binder is 8 mass % or less.Type: GrantFiled: July 11, 2016Date of Patent: March 17, 2020Assignee: NIPPON SHEET GLASS COMPANY, LIMITEDInventor: Shinichi Kato
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Patent number: 10590024Abstract: There is provided a method for producing a multicore optical fiber while reducing the mass of a glass block to be connected to a common cladding tube. A production method for a multicore optical fiber includes in order, a preform forming step of forming a common cladding tube having a plurality of holes extending between a first end and a second end, an insertion step of inserting core rods in the holes in a state in which end portions of the core rods are recessed from the first end, a heat shrinkage step of reducing a diameter of the first end by heating, a sealing step of sealing the holes by connecting a glass block to the first end, and a drawing step of depressurizing insides of the holes from the second end and performing spinning from the first end while combining the common cladding tube and the core rods.Type: GrantFiled: January 8, 2018Date of Patent: March 17, 2020Assignee: SUMITOMO ELECTRIC INDUSTRIES, LTD.Inventors: Takuji Nagashima, Tetsuya Nakanishi
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Patent number: 10590025Abstract: A glass precursor gel and a method of making a glass product from the glass precursor gel are disclosed. The glass precursor gel includes a bulk amorphous oxide-based matrix that is homogeneously chemically mixed and includes 30 mol % to 90 wt. % silica and at least one of the following: (A) 0.1 mol % to 25 mol % of one or more alkali oxides in sum total, (B) 0.1 mol % to 25 mol % of one or more alkaline earth oxides in sum total, (C) 1 mol % to 20 mol % boric oxide, (D) 5 mol % to 80 mol % lead oxide, or (E) 0.1 mol % to 10 mol % aluminum oxide. A method of making a glass product from the glass precursor gel involves obtaining the glass precursor gel, melting the glass precursor gel into molten glass, and forming the molten glass into a glass product.Type: GrantFiled: February 8, 2018Date of Patent: March 17, 2020Assignee: Owens-Brockway Glass Container Inc.Inventors: Scott P. Cooper, Michael P. Remington, Scott Weil, Tilak Gullinkala, Sutapa Bhaduri
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Patent number: 10590026Abstract: A technical object of the present invention is to devise an alkali-free glass substrate having high devitrification resistance and high heat resistance. In order to achieve the above-mentioned technical object, the alkali-free glass substrate of the present invention includes as a glass composition, in terms of mol %, 60% to 80% of SiO2, 8% to 25% of Al2O3, 0% to less than 3% of B2O3, 0% to less than 1% of Li2O+Na2O+K2O, 0% to 10% of MgO, 1% to 15% of CaO, 0% to 12% of SrO, 0% to 12% of BaO, 0% to less than 0.05% of As2O3, and 0% to less than 0.05% of Sb2O3, and has a thickness of from 0.05 mm to 0.7 mm, a strain point of 700° C. or more, and a ?-OH value of less than 0.20/mm.Type: GrantFiled: May 11, 2016Date of Patent: March 17, 2020Assignee: NIPPON ELECTRIC GLASS CO., LTD.Inventors: Atsuki Saito, Tetsuya Murata
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Patent number: 10590027Abstract: Provided are a high performance glass fiber composition, and a glass fiber and a composite material thereof. The content, given in weight percentage, of each component of the glass fiber composition is as follows: 52-67% of SiO2, 12-24% of Al2O3, 0.05-4.5% of Sm2O3+Gd2O3, less than 2% of Li2O+Na2O+K2O, 10-24% of CaO+MgO+SrO, less than 16% of CaO, less than 13% of MgO, less than 3% of TiO2, and less than 1.5% of Fe2O3. The composition significantly improves the mechanical properties and the thermal stability of glass, significantly reduces the liquidus temperature and forming temperature of glass, and under equal conditions, significantly reduces the crystallisation rate of glass. The composition is particularly suitable for the tank furnace production of a high performance glass fiber having excellent thermal stability.Type: GrantFiled: March 21, 2016Date of Patent: March 17, 2020Assignee: JUSHI GROUP CO., LTD.Inventors: Yuqiang Zhang, Guorong Cao, Lin Zhang, Wenzhong Xing, Guijiang Gu
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Patent number: 10590028Abstract: Lithium silicate-wollastonite glass ceramics are described which are characterized by a controllable translucence and can be easily machined and therefore can be used in particular as restoration material in dentistry.Type: GrantFiled: September 2, 2016Date of Patent: March 17, 2020Assignee: Ivoclar Vivadent AGInventors: Marc Dittmer, Wolfram Höland, Markus Rampf, Marcel Schweiger
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Patent number: 10590029Abstract: The present invention relates to a manufacturing method for a camera window and a camera window manufactured thereby. A conventional camera window is configured such that an etching pattern is provided on a back surface of a glass sheet, and a deposition layer is provided on the etching pattern, thereby improving reflectivity, whereby indirect external recognition of the etching pattern is performed, but in the present invention, a distinctive pattern is provided on a front surface of a glass sheet such that direct external recognition of the pattern is possible, whereby it is possible to recognize a distinctive pattern line.Type: GrantFiled: January 9, 2018Date of Patent: March 17, 2020Assignee: UTI, Inc.Inventors: Deok Young Park, Jae Young Hwang, Hak Chul Kim, Tea Joo Ha
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Patent number: 10590030Abstract: A glass plate includes a main surface, and a microscopic asperity surface disposed on the main surface, the microscopic asperity surface forming peaks and valleys. When a reference plane is defined as a plane at a center, in a direction of height, of an interval of highest frequency in a histogram of height of shape data of a square region having 2 ?m per side in the microscopic asperity surface, the number of peaks that are higher than the reference plane by 20% or more of a maximum height difference in the square region is in a range between 1 or more and 300 or less.Type: GrantFiled: May 25, 2018Date of Patent: March 17, 2020Assignee: AGC Inc.Inventors: Misa Inamoto, Naoki Okahata, Takashi Shibuya
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Patent number: 10590031Abstract: An ellipsometry system detects and/or identifies significant corrosion on glass, such as on soda-lime-silica based float glass. In certain example embodiments, there is provided a method and/or system using ellipsometry to detect and/or identify significant corrosion on soda-lime-silica based glass, so that such significantly corroded glass can be identified and not coated with a low-E coating and/or not used in applications where optical appearance is important. The ellipsometry system may be part of, or used in connection with, a sputtering apparatus/system for sputter-depositing low-E coatings on glass, so that whether to pass a piece of glass to the sputtering apparatus/system is based on whether significant corrosion is detected on the glass.Type: GrantFiled: May 11, 2018Date of Patent: March 17, 2020Assignee: GUARDIAN GLASS, LLCInventors: Ali Mohammadkhah, Shuang Ji, Jay Riggins, Kevin R. Fulton
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Patent number: 10590032Abstract: A substrate having inner and outer major surfaces, a plurality of edge surfaces, and a plurality of corner surfaces; and at least one of: (i) a coating applied over a limited area of the outer major surface of the substrate to produce a composite structure, (ii) an intermediate layer applied to the inner major surface of the substrate, and (iii) an elongate discontinuity disposed at one or more corners of the substrate, each of which operates to reduce catastrophic failures in the substrate resulting from a dynamic sharp impact to the outer major surface of the substrate.Type: GrantFiled: October 22, 2015Date of Patent: March 17, 2020Assignee: CORNING INCORPORATEDInventors: Petr Gorelchenko, Jason Thomas Harris, Guangli Hu, Khaled Layouni, Po-Jen Shih, Bin Zhang
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Patent number: 10590033Abstract: An article is provided which includes a substrate and a film disposed on a surface of the substrate. The film includes an aluminum concentration of about 45 atomic % to about 50 atomic %, a nitrogen concentration of about 26 atomic % to about 46 atomic % and an oxygen concentration of from about 4 atomic % to about 24 atomic %. The substrate comprises a bow of less than about 0.0005 meters.Type: GrantFiled: February 28, 2018Date of Patent: March 17, 2020Assignee: Corning IncorporatedInventor: Charles Andrew Paulson
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Patent number: 10590034Abstract: Coated articles for use in backsplash applications such as kitchen backsplashes, bathroom backsplashes, and bathroom floor/wall applications. The coated article includes a coating on a glass substrate, where the coating includes a plurality of dielectric layers and a plurality of metal-based layers and is configured so that the coated article has desirable glass side reflective coloration (e.g., bronze, blue, silver, and/or grey coloration) and is sufficiently opaque to hide adhesive used to adhere the coated article to walls/floors. The coating may be configured to realize thermal stability in order to have minimal or reduced glass side reflective color shift up heat treatment (e.g., thermal tempering).Type: GrantFiled: December 16, 2016Date of Patent: March 17, 2020Assignee: GUARDIAN GLASS HOLDING S.P.C.Inventors: Aritra Biswas, Gpoal Balachandran
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Patent number: 10590035Abstract: Low-emissivity coatings that are highly reflective to infrared-radiation. The coating includes three infrared-reflection film regions, which may each include silver.Type: GrantFiled: June 19, 2017Date of Patent: March 17, 2020Assignee: CARDINAL CG COMPANYInventor: Klaus Hartig
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Patent number: 10590036Abstract: The invention relates to a method for producing a composite material with a decorative coating, wherein a porous layer that includes pigment particles is applied onto a glass or glass ceramic substrate. The porous layer is filled with a polymer.Type: GrantFiled: October 20, 2014Date of Patent: March 17, 2020Assignee: SCHOTT AGInventors: Matthias Bockmeyer, Andrea Anton, Lutz Klippe, Claudia Kottenstedte
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Patent number: 10590037Abstract: An immersion weaving system includes a first drum immersed in a first bath of a liquid. The first drum is configured to form a glass strand from individual glass filaments. The immersion weaving system also includes a second drum immersed in the first bath of the liquid. The second drum is configured to form a yarn spool from the glass strand. The immersion weaving system further includes a loom immersed in a second bath of the liquid. The loom is configured to form a void-free glass cloth.Type: GrantFiled: March 27, 2017Date of Patent: March 17, 2020Assignee: International Business Machines CorporationInventors: Bruce J. Chamberlin, Matthew S. Kelly, Scott B. King, Joseph Kuczynski
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Patent number: 10590038Abstract: A hydrophobic admixture, for cementitious materials such as cement paste, mortar, and concrete, includes solid polymer particles with a coating of hydrophobic agent and surfactant. The solid polymer particles adhere to exterior surfaces of hydrated cement particles in the cement matrix. The solid polymer particles deliver the hydrophobic agent into the cement matrix which is hydrophilic. The hydrophobic agents are distributed uniformly throughout the cement matrix. The solid polymer particles can be crumb rubber particles derived from waste rubber tires, recycled plastics and similar solid materials. The hydrophobic liquid agent is derived from waste lubricant oil, spent motor oil, base oil, esters of fatty acids, vegetable oil and the like. Fine particles such as activated carbon, silica fume and spent catalyst can be employed to fill the large pores or cracks that develop in the cementitious matrix. The cured cementitious materials exhibit high contact angles and high compressive strengths.Type: GrantFiled: July 1, 2019Date of Patent: March 17, 2020Inventors: Maw-Tien Lee, Zih-Yao Shen, Chi-Yao Chen, Fu-Ming Lee, John Lee
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Patent number: 10590039Abstract: A formulation and method for obtaining ultra-high performance concretes, which provide a concrete with good mechanical properties of, inter alia, traction, compression, deformation, durability, ductility and toughness, with reduced related costs.Type: GrantFiled: December 6, 2016Date of Patent: March 17, 2020Assignee: CEMENTOS ARGOS S.A.Inventor: Andres Mauricio Nuñez Lopez
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Patent number: 10590040Abstract: A macro-cement and associated methods useful for preparing pastes, mortars, concretes and other cement-based materials having high workability, high density, and high strength are disclosed. A method of producing a macro-cement includes cement, supplemental cementitious materials (SCM's), including siliceous submicron-sized particles and nano-sized particles, and polymers in the form of liquid or dry chemical admixtures for concrete. The cement mixture may be used for making ultra-high performance concrete (UHPC).Type: GrantFiled: December 13, 2018Date of Patent: March 17, 2020Assignee: MACROCEMENT INDUSTRIES LTD.Inventors: Alexander Ozersky, Alexander Khomyakov
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Patent number: 10590041Abstract: A refractory object can include at least approximately 10 wt % Al2O3 and at least approximately 1 wt % SiO2. In an embodiment, the refractory object can include an additive. In a particular embodiment, the additive can include TiO2, Y2O3, SrO, BaO, CaO, Ta2O5, Fe2O3, ZnO, or MgO. The refractory object can include at least approximately 3 wt % of the additive. In an additional embodiment, the refractory object can include no greater than approximately 8 wt % of the additive. In a further embodiment, the creep rate of the refractory object can be at least approximately 1×10?6 h?1. In another embodiment, the creep rate of the refractory object can be no greater than approximately 5×10?5 h?1. In an illustrative embodiment, the refractory object can include a glass overflow trough or a forming block.Type: GrantFiled: January 12, 2018Date of Patent: March 17, 2020Assignee: SAINT-GOBAIN CERAMICS & PLASTICS, INC.Inventors: Olivier Citti, Julien P. Fourcade, Andrea L. Kazmierczak
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Patent number: 10590042Abstract: Resins for 3D printing of a preceramic composition loaded with a solid polymer filler, followed by converting the preceramic composition to a 3D-printed ceramic material, are described. Some variations provide a preceramic composition containing a radiation-curable liquid resin formulation and a solid polymer filler dispersed within the liquid resin formulation. The liquid resin formulation is compatible with stereolithography, UV curing, and/or 3D printing. The solid polymer filler may be an organic polymer, an inorganic polymer, or a combination thereof. The solid polymer filler may itself be an inorganic preceramic polymer, which may have the same composition as a polymerized variant of the liquid resin formulation, or a different composition. Many compositions are disclosed as options for the liquid resin formulation and the solid polymer filler.Type: GrantFiled: April 5, 2018Date of Patent: March 17, 2020Assignee: HRL Laboratories, LLCInventors: Zak C. Eckel, Jacob M. Hundley, Robert Mone
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Patent number: 10590043Abstract: Embodiments of the present invention describe a method for continuous manufacture of a gel material comprising the steps of: forming a gel sheet by dispensing a gel precursor mixture onto a moving element; allowing gelation to occur to the gel precursor mixture; and cooling the formed gel with a cooling system, thereby reducing the rate of solvent evaporation therefrom.Type: GrantFiled: September 12, 2016Date of Patent: March 17, 2020Assignee: ASPEN AEROGELS, INC.Inventors: George L Gould, Kevin A Schmidt, Christopher L Marlette, Shahrooz Zaghi
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Patent number: 10590044Abstract: An engineered matrix is provided to blunt and self-heal matrix cracks to reduce oxygen ingress into a fiber reinforced composite.Type: GrantFiled: January 20, 2017Date of Patent: March 17, 2020Assignee: United States of America as Represented by the Administrator of National Aeronautics and Space AdministrationInventor: Sai V. Raj
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Patent number: 10590045Abstract: Disclosed is a liquid fertilizer including: (i) an aqueous composition including ammonium thiosulfate; and (ii) a complex of a metal ion and a chelating agent, wherein the metal ion is selected from the group consisting of zinc, manganese, copper, iron, magnesium, calcium, potassium, and molybdenum. The complex lowers the freeze point of the aqueous composition when creating a liquid fertilizer including the ammonium thiosulfate and the complex. Optionally, the liquid fertilizer includes borate ions. Methods of using the liquid fertilizer are also disclosed.Type: GrantFiled: October 12, 2015Date of Patent: March 17, 2020Assignee: HYDRITE CHEMICAL CO.Inventors: Dean Blankenburg, Eric M. Johnson, Nathan Ludtke
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Patent number: 10590046Abstract: The disclosure relates to a composting device including a housing defining an interior with an access opening providing access to the interior, a composter bin located within the interior and in communication with the access opening, and a door mounted to the housing that includes a fascia.Type: GrantFiled: May 19, 2016Date of Patent: March 17, 2020Assignee: Whirlpool CorporationInventors: Abhishek P. Buzruk, Christopher C. Wilcox
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Patent number: 10590047Abstract: The present disclosure is directed to a nitrocellulose-based propellant composition comprising: (a) a nitrate ester-based propellant comprising nitrocellulose; and (b) a stabiliser comprising a non-aromatic compound (12) consisting of a general ionone formula (12-I), (12-II), (12-III) or (12-IV): wherein R1 represents a ketone, hydroxyl, carboxyl, aldehyde or an unsaturated alkyl group, preferably —C(O)CH3 (corresponding to alpha, beta, gamma and pseudo ionone).Type: GrantFiled: February 25, 2016Date of Patent: March 17, 2020Assignee: PB CLERMONTInventors: Alain Dejeaifve, Rowan Dobson
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Patent number: 10590048Abstract: An integrated process for producing C3-C4 olefins or di-olefins including: contacting a hydrocarbon feed and a catalyst feed in a fluidized dehydrogenation reactor under conditions such that a product mixture is formed and the catalyst is at least partially deactivated; transferring the product mixture and the catalyst from the reactor to a cyclonic separation system under conditions such that the product mixture is converted to form a new product mixture and is separated from the catalyst; transferring at least a portion of the catalyst to a regenerator vessel and heating it in order to combust the coke deposited thereon; subjecting the catalyst to a conditioning step to form an oxygen-containing, at least partially reactivated catalyst; and transferring the partially reactivated catalyst back to the fluidized dehydrogenation reactor.Type: GrantFiled: January 23, 2019Date of Patent: March 17, 2020Assignee: Dow Global Technologies LLCInventor: Matthew T. Pretz
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Patent number: 10590049Abstract: The present invention provides a method for producing tetrafluoropropene represented by formula (1) by bringing monochlorotrifluoropropene represented by formula (2) into contact with anhydrous hydrogen fluoride in the presence of a catalyst, the method being capable of maintaining the conversion of the starting material and the selectivity for the target product within an excellent range, while reducing degradation of the catalyst to maintain the reaction for a long time.Type: GrantFiled: February 3, 2017Date of Patent: March 17, 2020Assignee: DAIKIN INDUSTRIES, LTD.Inventors: Shun Ohkubo, Takashi Usui, Takehiro Chaki, Daisuke Karube
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Patent number: 10590050Abstract: Disclosed is a method for co-producing various alkenyl halides and hydrofluoroalkanes: cis-1-chloro-3,3,3-trifluoropropene is introduced into a first reactor to carry out an isomerization reaction in the presence of a first catalyst, and the reaction product is rectified to obtain a product trans-1-chloro-3,3,3-trifluoropropene; and 30-70 wt % of trans-1-chloro-3,3,3-trifluoropropene and hydrogen fluoride are mixed and then introduced into a second reactor to carry out a reaction in the presence of a second catalyst to obtain a second reactor reaction product; the second reactor reaction product is introduced into a phase separator for separation, and the obtained organic phase is rectified to obtain the products trans-1,3,3,3-tetrafluoropropene, cis-1,3,3,3-tetrafluoropropene and 1,1,1,3,3-pentafluoropropane. The invention has the advantages of simple process, high efficiency, high operation flexibility, less investment and low energy consumption.Type: GrantFiled: June 25, 2018Date of Patent: March 17, 2020Assignee: Zhejiang Quhua Fluor-Chemistry Co LtdInventors: Jiangyong Hong, Bo Yang, Yan Zhang, Guojun Yu, Yang Zhao, Hao Ouyang, Haitao Gong
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Patent number: 10590051Abstract: The present invention provides a method for producing a target fluorine-containing olefin with high conversion and selectivity using a process comprising a dehydrofluorination reaction of a hydrofluorocarbon. The method comprises a first reaction step comprising subjecting a hydrofluorocarbon to dehydrofluorination in the presence of a catalyst. The hydrofluorocarbon is a compound represented by Formula (1): RfCFYCHZ2, wherein Rf represents a straight or branched C1-3 perfluoroalkyl group, and Y and Z each independently represent H or F wherein when all Zs are H, Y represents F. The catalyst comprises chromium oxide represented by the chemical formula: CrOm (1.5<m<3).Type: GrantFiled: May 18, 2016Date of Patent: March 17, 2020Assignee: DAIKIN INDUSTRIES, LTD.Inventors: Takehiro Chaki, Shun Ohkubo, Daisuke Karube
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Patent number: 10590052Abstract: A process for producing a main (hydro)halocarbon compound, including the formation of a mixture of compounds including hydrogen fluoride, Z-3,3,3-trifluoro-1-chloropropene and one or more other (hydro)halocarbon compounds, distillation of this mixture making it possible to collect, firstly, an azeotropic composition, and, secondly, at least one of the compounds of the mixture. The (hydro) halocarbon compounds are preferably selected among tetrachlorofluoropropanes, trichlorodifluoropropanes, dichlorotrifluoropropanes, chlorotetrafluoropropanes, pentafluoropropanes, dichlorodifluoropropenes, chlorotrifluoropropenes and tetrafluoropropenes.Type: GrantFiled: June 26, 2018Date of Patent: March 17, 2020Assignee: ARKEMA FRANCEInventors: Dominique Deur-Bert, Anne Pigamo, Philippe Bonnet
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Patent number: 10590053Abstract: It is disclosed a process to produce a bio-product starting from a ligno-cellulosic feedstock, comprising a pre-hydrolysis step of the ligno-cellulosic feedstock in one or more pre-hydrolysis vessels to produce a liquid pre-hydrolyzate comprising water and water soluble hemicellulose, followed by a multi-step hydrolysis of the water soluble hemicellulose. The hydrolysis steps are conducted in separated vessel. The liquid pre-hydrolyzate is subjected to a partial hydrolysis step in a first hydrolysis vessel, to produce a first hydrolyzate. A portion of the first hydrolyzate, comprising remnant water soluble hemicellulose, is recirculated in at least one pre-hydrolysis vessel and subjected to a second hydrolysis step. Another portion of the first hydrolyzate comprising monomeric sugars is removed and converted to the bio-product, preferably after a refining hydrolysis step. The process also produces a hemicellulose-depleted feedstock which is preferably treated to produce a cellulosic pulp.Type: GrantFiled: December 1, 2016Date of Patent: March 17, 2020Assignee: VALMET AKTIEBOLAGInventors: Patrizia Ferrando, Marco Bernardi, Dario Giordano, Lari Lammi, Mats Nordgren
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Patent number: 10590054Abstract: There are provided methods and systems to form propylene chlorohydrin by hydrolysis of dichloropropane in presence of Lewis acid and to further form propylene oxide from the propylene chlorohydrin.Type: GrantFiled: May 29, 2019Date of Patent: March 17, 2020Assignee: Calera CorporationInventors: Michael Joseph Weiss, Kyle Self, Thomas A Albrecht, Margarete K Leclerc
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Patent number: 10590055Abstract: A method of producing a solid glycerol derived material includes the steps of combining glycerol with a metal oxide, the glycerol having a water content of between about 5 and 50%, and the rate of combination of the glycerol and the metal oxide and the amount of the metal oxide being selected so that at least part of the water present in the glycerol reacts with the metal oxide in an exothermic reaction and at least part is driven off by heat produced in the exothermic reaction to produce the solid glycerol derived material.Type: GrantFiled: July 22, 2014Date of Patent: March 17, 2020Assignee: BIO-ENERGY INGREDIENTS LIMITEDInventors: Richard Alwyn Houseman, Abraham Christo Venter
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Patent number: 10590056Abstract: Disclosed herein, inter alia, are compositions and methods useful for treating non-alcoholic fatty liver diseases.Type: GrantFiled: April 11, 2018Date of Patent: March 17, 2020Assignee: CITY OF HOPEInventors: Donna D. Yu, Barry M. Forman
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Patent number: 10590057Abstract: Methods of C—H bond fluorination using non-heme manganese catalyst are described herein. For example, a method comprises providing a reaction mixture including a non-heme manganese catalyst, a substrate comprising an sp3 C—H bond and a fluorinating agent and converting the sp3 C—H bond to a C—F bond in the presence of the non-heme manganese catalyst or a derivative thereof.Type: GrantFiled: December 14, 2016Date of Patent: March 17, 2020Assignee: The Trustees of Princeton UniversityInventors: John T. Groves, Xinyi Chen
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Patent number: 10590058Abstract: A process for synthesizing a product of formula Br—(CH2)n—R by hydrobromination, by reacting: a reagent of formula (I) R1-CH?CH—R2 in which R1 and R2, identical or different, are chosen from H or an alkyl radical comprising 1 to 30 carbon atoms, which is saturated or unsaturated, linear or branched, functionalized or non-functionalized, with a molar excess of HBr relative to the reagent of formula (I), in the presence of a radical initiator, and optionally in the presence of at least one solvent, said process including a step A of mixing at least reagent I and the HBr, each of the latter arriving in the form of a flow of liquid into a mixing device dA.Type: GrantFiled: August 7, 2014Date of Patent: March 17, 2020Assignee: ARKEMA FRANCEInventors: Bernard Berthe, Bernard Pees, Philippe Annoot, Jean-Luc Dubois, Ornella Zovi
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Patent number: 10590059Abstract: Provided herein are compounds useful for the preparation of compounds that have retinoid-like biological activity. Also provided herein are processes for the preparation of compounds that have retinoid-like biological activity.Type: GrantFiled: November 16, 2018Date of Patent: March 17, 2020Assignee: Io Therapeutics, Inc.Inventors: Roshantha A. Chandraratna, Vidyasagar Pradeep Vuligonda, Thomas Jacks, Peter Wade, Andrew Thompson
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Patent number: 10590060Abstract: A process for synthesizing at least one levulinate ester, said process comprising the reaction of furfuryl alcohol with at least one other alcohol in the presence of water and at least one catalyst, said furfuryl alcohol being present in a quantity of at least 5% by weight, based on the total weight of the alcohols, and said catalyst comprising at least one triflate ligand and at least one metal selected from bismuth, gallium, aluminum, tin and iron.Type: GrantFiled: June 30, 2017Date of Patent: March 17, 2020Assignees: LE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE POITIERSInventors: Alban Chappaz, Francois Jerome, Karine De Oliveira Vigier, Eric Muller, Jonathan Lai, Matthieu Corbet, Didier Morvan
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Patent number: 10590061Abstract: Processes for continuous preparation of bioproducts are described herein. The processes include contacting fatty acid glycerides with alcohols in the presence of an acidic heterogeneous catalyst and separating the fatty acid alkyl esters from the reaction products.Type: GrantFiled: April 9, 2018Date of Patent: March 17, 2020Assignee: BENEFUEL, INC.Inventors: William A. Summers, Rebecca Williams, Danny Gulledge, Robert Barrie Tripp
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Patent number: 10590062Abstract: A process for making methyl esters in high yields is provided. The process comprises contacting aliphatic or aromatic aldehydes and methanol with an iron catalyst, to catalyze the dehydrogenative coupling between aliphatic or aromatic aldehydes and methanol. The reaction is highly selective (<99.9%) toward the formation of methyl esters over homoesters and alcohols and operates at temperatures of less than 100° C. for 2-8 hours.Type: GrantFiled: November 13, 2018Date of Patent: March 17, 2020Assignee: Eastman Chemical CompanyInventors: Sumit Chakraborty, Steven J. Adams, Robert Thomas Hembre, Leslie Sharon Depew
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Patent number: 10590063Abstract: Compositions and methods for inhibiting, treating, and/or preventing fatty acid metabolism disorders, particularly fatty acid oxidation disorders, in a subject are provided.Type: GrantFiled: November 7, 2016Date of Patent: March 17, 2020Assignee: THE CHILDREN'S HOSPITAL OF PHILADELPHIAInventors: Harry Ischiropoulos, Paschalis-Thomas Doulias
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Patent number: 10590064Abstract: The present invention relates to alanine N-acetic acid precursors of formula (i) COOM-CH(CH3)—NH—(CH2CN), wherein M is hydrogen (alanine N-monoacetonitrile), or (ii) COOM-CH(CH3)—N—(CH2CN)2, wherein 0 to 50% of all M is sodium or potassium and 50 to 100% of all M is hydrogen (alanine N,N-diacetonitrile and its partial sodium or potassium salts) comprising L-alanine to D-alanine in a range of from 75:25 to 50:50 (L:D), or (iii) COOM-CH(CH3)—N—(CH2CONH2)2, wherein M is hydrogen (alanine N,N-diacetamide), in the form of crystals, and relates to a process to prepare these precursors and their use, especially to give MGMA or MGDA.Type: GrantFiled: December 21, 2015Date of Patent: March 17, 2020Assignee: NOURYON CHEMICALS INTERNATIONAL B.V.Inventors: Albertus Jacobus Maria Bouwman, Hubertus Johannes Jongen, Roy Gérard Doppen, Martin Heus, Elwin Schomaker
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Patent number: 10590065Abstract: Provided herein are compounds of the formulas: (I) wherein: n, X2, R3, R3?, R4, R4?, R5, R5?, R6, and R6? are as defined herein. Pharmaceutical compositions of the compounds are also provided. In some aspects, these compounds may be used for the treatment of diseases, including diabetic peripheral neuropathy or cancer.Type: GrantFiled: June 24, 2015Date of Patent: March 17, 2020Assignee: UNIVERSITY OF KANSASInventors: Brian S. J. Blagg, Rick T. Dobrowsky, Mercy Anyika
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Patent number: 10590066Abstract: The present disclosure is directed to resins and to polymers, copolymers, and blends formed therefrom.Type: GrantFiled: August 23, 2018Date of Patent: March 17, 2020Assignee: 3D-BIOMATERIALS, LLCInventors: Sajal Das, Patrick Shipman, Scott Shuler
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Patent number: 10590067Abstract: The present invention provides novel compounds which activate the Kv7 potassium channels. Exemplary compounds of the invention have the structure of Formula 1. Separate aspects of the invention are directed to pharmaceutical compositions comprising said compounds and uses of the compounds to treat disorders responsive to the activation of Kv7 potassium channels.Type: GrantFiled: February 20, 2018Date of Patent: March 17, 2020Assignee: H. Lundbeck A/SInventors: Mario Rottlander, Anette Graven Sams, Xiaofang Wang, Debasis Das, Jian Hong, Shu Hui Chen
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Patent number: 10590068Abstract: A satellite system operates at altitudes between 180 km and 350 km relying on vehicles including an engine to counteract atmospheric drag to maintain near-constant orbit dynamics. The system operates at altitudes that are substantially lower than traditional satellites, reducing size, weight and cost of the vehicles and their constituent subsystems such as optical imagers, radars, and radio links. The system can include a large number of lower cost, mass, and altitude vehicles, enabling revisit times substantially shorter than previous satellite systems. The vehicles spend their orbit at low altitude, high atmospheric density conditions that have heretofore been virtually impossible to consider for stable orbits. Short revisit times at low altitudes enable near-real time imaging at high resolution and low cost. At such altitudes, the system has no impact on space junk issues of traditional LEO orbits, and is self-cleaning in that space junk or disabled craft will de-orbit.Type: GrantFiled: January 11, 2018Date of Patent: March 17, 2020Assignee: Skeyeon, Inc.Inventors: Ronald E. Reedy, Thomas E. Schwartzentruber
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Patent number: 10590069Abstract: A pinene-derived diisocyanate compound, a process for forming a pinene-derived diisocyanate compound, and an article of manufacture containing a polyurethane polymer are disclosed. The process for forming the pinene-derived diisocyanate compound includes oxidizing the pinene to form a pinene-derived ketone compound, converting the pinene-derived ketone compound to a diamine compound in subsequent reaction steps, and reacting the diamine compound with phosgene to form the pinene-derived diisocyanate compound. The polyurethane polymer is synthesized in a reaction between a pinene-derived diisocyanate compound and a polyol.Type: GrantFiled: October 6, 2017Date of Patent: March 17, 2020Assignee: International Business Machines CorporationInventors: Brandon M. Kobilka, Joseph Kuczynski, Jacob T. Porter, Jason T. Wertz
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Patent number: 10590070Abstract: Compounds, pharmaceutical compositions, methods and kits are described for treating or preventing neurodegenerative diseases such as Alzheimer's disease.Type: GrantFiled: August 10, 2016Date of Patent: March 17, 2020Assignee: Alzheon, Inc.Inventors: Petr Kocis, Martin Tolar, John Hey
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Patent number: 10590071Abstract: Isosulfan blue and processes for the preparation thereof are provided. A process is also provided for preparation of the intermediate, 2-chlorobenzaldehyde-5-sulfonic acid, sodium salt of formula (2), used in the preparation thereof and a procedure for the isolation of benzaldehyde-2,5-disulfonic acid, di-sodium salt of the formula (3). Also provided is a process for the preparation of an isoleuco acid of formula (4), which upon oxidation gives rise to isosulfan blue of pharmaceutical grade which can be used for preparation of pharmaceutical formulations. The isolation and purification procedures provided in the process provide substantially pure isosulfan blue with HPLC purity 99.5% or greater.Type: GrantFiled: October 25, 2018Date of Patent: March 17, 2020Assignee: Apicore US LLCInventors: Ravishanker Kovi, Satyam Nampalli, Peter Xavier Tharial