Abstract: A subjective optometry apparatus includes an optometry unit having an optical member, being located in front of a subject eye, and changing optical characteristics of a target light flus with using the optical member, and a measurement optical system that has a light projecting optical system for applying measurement light emitted from a measurement light source to a fundus of the subject eye through the optometry unit, and a light receiving optical system in which a detector receives reflected light of the measurement light reflected on the fundus of the subject eye through the optometry unit, and that objectively measures the optical characteristics of the subject eye. An optical axis of the measurement optical system is set to be off-axis from an optical axis of the optical member in the optometry unit.

Abstract: A portable device for the measurement of refractive error in the eye is disclosed. The device generally includes a liquid lens that the patient looks through, a projective array of static lenses, an electronic display, a system of electronics, and software that controls the potential applied to the liquid lens, controls the display, and runs the algorithm that processes patient feedback in order to determine the correct corrective lens powers. Housed in a singular body that can be held and positioned in front of the patient's eye, the device allows direct feedback and interaction by a patient using a remote control. Altogether, the device is automatically determines a voltage of the liquid lens that provides the patient with the clearest vision, which can be used to calculate the prescription corrective lens power.

Abstract: The visual function test device of an embodiment comprises a test subject display device and an operator display device. A target display portion displays a target image to be viewed by the test subject onto the test subject display device. A visual axis estimation portion estimates a visual axis of the test subject when the target image is viewed. A position display portion displays a display position of the test target image and a viewpoint position that corresponds to the estimated visual axis, onto the operator display device, and thus a tester can objectively recognize a gazing state of the test subject and surely perform the test, which enhances the reliability of the test.

Abstract: The invention provides a calibration method and a calibration device of a system for measuring corneal parameters, and particularly the invention provides a system calibration method and device for geometric distortion, caused by camera shooting angle when measuring cornea-related parameters, of a digital slit lamp and a system of similar principles based on machine vision.

Abstract: The present disclosure relates to sensor systems for electronic ophthalmic devices. In certain embodiments, the sensor systems may comprise a selection layer configured to reject light from the eye within a first range of incident angles and allow light from the eye within a second range of incident angles to pass through the selection layer. The sensor system may comprise a plurality of photodiodes disposed below the selection layer and configured to detect the light from the eye within the second range of incident angles that is allowed to pass through the selection layer. The sensor system may comprise an output circuit electrically coupled to the plurality of photodiodes and configured to output a signal indicative of which photodiode of the plurality of photodiodes detected the light.

Abstract: The invention relates to a method for highly accurate determining of a pupil diameter of an eye, using a camera system for spatial capturing of objects, the method including: imaging stereoscopic capturing of an eye region, wherein for an eye of the eye region a first and a second stereoscopic image arise. For each of the two stereoscopic images the method further includes: Transferring of the captured eye region into a color space. Determining of a region, within the captured eye region, as a region within a pupil of the captured eye region. Determining of a closed outer edge of the region within the pupil. Iterative determining of a closed outer pupil edge. The invention further relates to a corresponding device.

Abstract: An image processor performs a histogram acquisition step of acquiring a histogram representing a distribution of gradation values of pixels in a fundus color image captured by irradiating a fundus with a plurality of beams of single-color light having different wavelengths, the histogram being acquired for each channel corresponding to each beam of single-color light, a histogram correction step of acquiring a corrected histogram by correcting the histogram of each channel acquired in the histogram acquisition step, of which a target pattern is set for each channel in advance, so as to fit to the corresponding target pattern, and a color tone corrected image generation step of generating a color tone corrected image, in which a distribution of gradation values for each channel is represented by the corrected histogram, based on the corrected histogram of each channel.

Abstract: An ophthalmologic apparatus according to the embodiments includes an OCT optical system, an alignment unit, an image forming unit, a first calculator, and a second calculator. The OCT optical system is configured to acquire OCT data of a fundus of a subject's eye by projecting measurement light onto the fundus. The alignment unit is configured to perform alignment of the OCT optical system with reference to a predetermined site of the subject's eye. The image forming unit is configured to form a tomographic image of the fundus based on the OCT data acquired by the OCT optical system which has been aligned by the alignment unit. The first calculator is configured to calculate a first tilt angle of the tomographic image. The second calculator is configured to calculate a second tilt angle of the fundus by correcting the first tilt angle based on alignment result of the OCT optical system with respect to the predetermined site by the alignment unit.

Abstract: An ophthalmic apparatus may include a first light source configured to output a first light, a second light source configured to output a second light, a first interferometer configured to execute an examination of a first range using first interference light, and a second interferometer configured to execute an examination of a second range using second interference light, the second range being different from the first range. A central wavelength of the first light may be different from a central wavelength of the second light. A first optical path and a second optical path may at least partially overlap with each other, the first optical path being an optical path of the first light, and the second optical path being an optical path of the second light. The examination of the first range and the examination of the second range may be able to be executed simultaneously.

Abstract: Methods, sensors, and systems that prevent or reduce data loss when more than one external sensor transceiver is used with a sensor. A sensor may receive a transceiver identification (ID) of an external transceiver conveyed from the external transceiver and determine whether the received transceiver ID is a new transceiver ID. If sensor determines the received transceiver ID to be a new transceiver ID, the sensor may store the received transceiver ID in a nonvolatile storage medium of the sensor and convey, using the sensor, measurement information stored in the nonvolatile storage medium to the external transceiver.

Abstract: Methods and devices to monitor an analyte in body fluid are provided. Embodiments include continuous or discrete acquisition of analyte related data from a transcutaneously positioned in vivo analyte sensor automatically or upon request from a user.

Abstract: A method, system and article of manufacture is disclosed. The method includes providing a spatial navigator outside of a thermal therapy region; receiving a plurality of analog-to-digital conversion (ADC) readouts from an MRI device at a plurality of time points, wherein the ADC readouts comprise a first ADC readout acquired at a first time point, and one or more additional ADC readouts acquired at subsequent time points; processing the ADC readouts to obtain a frequency of the spatial navigator at each of the time points; obtaining a main magnetic field (B0) drift of the MRI device based on the frequency of the spatial navigator at a particular time point and the frequency of the spatial navigator at the first time point; and obtaining the temperature change at the particular time point based on the B0 drift.

Abstract: A method for locating a functional brain tissue by electrical stimulation includes performing electrical stimulations of different areas of the brain tissue to activate brain tissue regions identifying the functional brain tissue, recording an image or a video sequence of the brain tissue during and/or after a stimulation, comparing the recorded image or the video sequence with a reference image or a reference video sequence recorded without stimulation to determine a position of the brain tissue region that is activated by the stimulation. At least two stimulations of a plurality of electrical stimulations are performed, one directly after the other or simultaneously, and the recording of an image or a video sequence of the portion of brain tissue takes place during and/or after each performance of one of the at least two stimulations or during and/or after the simultaneous performance of the at least two stimulations.

Abstract: Sleep monitoring and stimulation comprises collecting actigraphy data from a user. The user's sleep phase is determined using the actigraphy data. At least one stimulation, determined at least in part on the sleep phase, is directed towards the user. Subsequent actigraphy data is collected from the user. The actigraphy data and subsequent actigraphy data is used to determine the user's subsequent sleep phase. The stimulation is modified, based at least in part upon the subsequent sleep phase.

Abstract: Methods for treating a wound include positioning a wound filler having a coating agent containing a fluorescent material proximate the wound. The wound filler is removed after a time period. The wound is then scanned using a fluorescence scanner to determine whether a portion of the wound filler remains at the wound. In response to the portion of the wound filler remaining at the wound, the portion of the wound filler is removed. Other methods and systems are presented.

Abstract: A fluorescence imaging device detects fluorescence in parts of the visible and invisible spectrum, and projects the fluorescence image directly on the human body, as well as on a monitor, with improved sensitivity, video frame rate and depth of focus, and enhanced capabilities of detecting distribution and properties of multiple fluorophores. Direct projection of three-dimensional visible representations of florescence on three-dimensional body areas advantageously permits viewing of it during surgical procedures, including during cancer removal, reconstructive surgery and wound care, etc. A NIR laser and a human visible laser (HVL) are aligned coaxially and scanned over the operating field of view. When the NIR laser passes over the area where the florescent dye is present, it energies the dye which emits at a shifted NIR frequency detected by a photo diode. The HVL is turned on when emission is detected, providing visual indication of those positions.

Abstract: Sleep enhancement system for assistance, monitoring, informing, and improving sleep habits of a user. A utilized monitoring device gathers user's vital signs for transmission to a smart device while an environment sensor gathers information from the surroundings which is then sent to an environment transmitter. Signals from the smart device and environment transmitter are transmitted to a processor by wireless transmission such as by electromagnetic waves, radio waves, infrared, sound or by being reported by audio or visual transmission. Signals are stored for current or future commands to control the environment, smart devices, and appliances for a user. In addition to being able to control these, an input to the ABTT terminus, such as heat or cold, can be applied to encourage entry into sleep or wake from sleep, as well as release of supplements or drugs through a patch placed on the ABTT terminus or another bodily region.

Abstract: The present invention relates to a method and apparatus for estimating the energy consumption of a person on the basis of heart rate data. In the method, the beat rate of heart is measured with a sensor or previously measured heart rate data are input for providing heart rate data and the energy consumption of a person is determined on the basis of heart rate data. According to the invention, a first threshold value is selected for the mass of the person and in case the mass of the person is larger than the first threshold value, energy consumption is calculated using a formula taking into account the deviation of the person's mass from the said first threshold value. The invention allows getting more accurate energy consumption estimates especially for overweight persons.

Abstract: An electronic device includes a camera, an ambient light sensor, and a proximity sensor. The electronic device uses one or more of the camera and the proximity sensor to emit light into a body part of a user touching a surface of the electronic device and one or more of the camera, the ambient light sensor, and the proximity sensor to receive at least part of the emitted light reflected by the body part of the user. The electronic device computes health data of the user based upon sensor data regarding the received light. In some implementations, the electronic device may also include one or more electrical contacts that contact one or more body parts of the user. In such implementations, the health data may be further computed based on an electrical measurement obtained using the electrical contacts.

Abstract: A method and an apparatus for measuring a time-varying change in an amount of blood in a tissue include exciting a fluorescence agent in the blood, acquiring a time-varying light intensity signal during a pulsatile flow of the blood through the tissue volume, the pulsatile flow having a systolic and a diastolic phase resembling a conventional photoplethysmogram, and processing the acquired signal by applying a modified Beer-Lambert law to obtain the measurement of the time-varying change in the amount of blood in the tissue volume. The instantaneous molar concentration of the fluorescence agent is determined by utilizing a concentration-mediated change in a fluorescence emission spectrum of the fluorescence agent.

Abstract: The present invention relates to a device, system and method for determining pulse pressure variation of a subject. To enable more reliably determining pulse pressure variation of a subject the device comprises a signal input (11) configured to obtain an input signal representing a hemodynamic signal of the subject, a processor (12) configured to process the input signal and compute a pulse pressure variation and a signal output (13) configured to output the computed pulse pressure variation. The pulse pressure variation is computed by deriving a pulse height signal from the input signal, deriving a pulse height baseline and a de-trended pulse height signal from the pulse height signal as the ratio between the difference between extrema of the de-trended pulse height signal and the respective value of the pulse height baseline signal, and computing the pulse pressure variation from the de-trended pulse height signal and the pulse height baseline.

Abstract: A pulse wave measurement device includes an acceleration sensor that detects a vibration and a vibration transmitter that transmits a vibration caused by pulsation in a measured site, wherein a length of the vibration transmitter in a specific direction is longer than a length of the acceleration sensor in a longitudinal direction.

Abstract: A patient monitor device configured to display vital information of a living body includes: a display; and circuitry configured to individually display at least two types of the vital information of the living body on a plurality of display regions of the display. Each of the display regions includes: a numerical value display portion for displaying measured vital information of the living body as a numerical value; and a tab portion for notifying of completion of the measurement after the measurement of the vital information is completed, and tab portions of respective display regions are arranged in a line along an array of respective numerical value display portions.

Abstract: A venous pressure measurement apparatus includes: a pressure controller that causes an internal pressure of a cuff to he attached to a subject, to change; a pressure detector that detects the internal pressure of the cuff; and a processor that causes the pressure controller to change the internal pressure of the cuff, acquires a statistical value relating to a distribution of amplitudes of a plurality of pressure changes corresponding to pressure vibration that occurs in the cuff, and that is detected by the pressure detector, and estimates a venous pressure of the subject based on a change of the statistical value due to the change of the internal pressure of the cuff.

Abstract: A physiological detection device including a light source, an image sensor and a processor is provided. The light source illuminates a skin surface using a burst mode. The image sensor receives ejected light from skin tissues under the skin surface at a sampling frequency to successively generate image frames. The processor controls the light source and the image sensor, and calculates a physiological characteristic according to the image frames captured when the light source is illuminating light. The physiological detection device reduces the total power consumption by adopting the burst mode.

Abstract: The present disclosure relates to a neuromonitoring device. The device includes a probe, a handle, and an elastic prompt. The probe is connected to the handle; the probe includes a probe head, an elastic piece, and an elastic measuring piece; the probe head is connected to the elastic piece; the elastic measuring piece is connected to the elastic piece and is used to measure an elasticity value of the elastic piece and convert the elasticity value into an electrical signal; the elastic prompt is electrically connected to the elastic measuring piece and is used to receive the electrical signal and generate prompt information regarding the elasticity value based on the electrical signal.

Abstract: Various embodiments of a platform for providing electromyographic biofeedback are disclosed. The platform includes a sensor device having an IMU and electrodes for simultaneous tracking of IMU and EMG activity. The IMU and EMG data may be generated and leveraged in conjunction with a gaming application provided to a user while engaged to the sensor device to provide biofeedback therapy for rehabilitation.

Abstract: Described herein are user-wearable devices, and methods for use therewith, for monitoring for one or more types of arrhythmias based on a photoplethysmography (PPG) signal obtained using an optical sensor of a user-wearable device. A PPG based statistical and/or machine learning model is used to analyze a PPG signal, obtained using the optical sensor, to monitor for one or more types of arrhythmias including atrial fibrillation (AF). In response to detecting an arrhythmia based on the PPG signal, an electrocardiogram (ECG) signal is obtained using an ECG sensor of the user-wearable device. An ECG based statistical and/or machine learning model is used to analyze the ECG signal obtained using the ECG sensor of the user-wearable device to confirm or reject the arrhythmia detected based on the PPG signal and/or to perform arrhythmia discrimination. Obtained PPG and/or ECG signal segments can be provided to the model(s) to update the model(s).

Abstract: Techniques and devices for implementing the techniques for adjusting atrial arrhythmia detection based on analysis of one or more P-wave sensing windows associated with one or more R-waves. An implantable medical device may determine signal characteristics of the cardiac signal within the P-wave sensing window, determine whether the cardiac signal within the sensing window corresponds to a P-wave based on the determined signal characteristics, determine a signal to noise ratio of the cardiac signal within the sensing window, update the arrhythmia score when the P-wave is identified in the sensing window and the determined signal to noise ratio satisfies a signal to noise threshold.

Abstract: A biological information measurement system includes a dewar, a single imaging device, and a hardware processor. The dewar covers a head of a subject and contains sensors that are arranged for detecting biological signals. The single imaging device acquires an image in which three or more reference points and the dewar are captured, the reference points being set in relation to the subject. The hardware processor is configured to: measure brain neural activity of the subject based on the biological signals detected by the sensors; determine positional relationships between the reference points of the subject and the sensors based on the reference points and positional relationship data of the dewar; and re-determine the positional relationships between the reference point of the subject and the sensors, based on images that are acquired by the single imaging device at different times.

Abstract: A physiological monitor includes a cleat adapted to be securable to a subject such as a patient. The cleat includes an A electrode which includes an A electrode connector portion. The cleat also includes a B electrode which includes a B electrode connector portion. An equipment module is removably attached or removably attachable to the cleat in a transverse direction. The equipment module has an A module connector portion and a B module connector portion arranged such that the A and B module connector portions connect with the A and B electrode connector portions respectively when the equipment module is connected to the cleat thereby placing the cleat and equipment module in signal communication with each other.

Abstract: A method for generating a filtered EMG signal includes obtaining a combined signal, wherein the combined signal comprises an ECG signal and an EMG signal. A first high pass filter is applied to the combined signal and an ECG model signal is generated, based on the high pass filtered combined signal. The method further includes, generating a partially filtered EMG signal by subtracting the ECG model from the high pass filtered combined signal. A second high pass filter is then applied to the partially filtered EMG signal to generate a second EMG signal and to the ECG model signal to generate a second ECG model signal. A filtered EMG signal is generated based on the second EMG signal and the second ECG model by way of a gating technique.

Abstract: An MR Spectroscopy (MRS) system and approach is provided for diagnosing painful and non-painful discs in chronic, severe low back pain patients (DDD-MRS). A DDD-MRS pulse sequence generates and acquires DDD-MRS spectra within intervertebral disc nuclei for later signal processing and diagnostic analysis. An interfacing DDD-MRS signal processor receives output signals of the DDD-MRS spectra acquired and is configured to optimize signal-to-noise ratio by an automated system that selectively conducts optimal channel selection, phase and frequency correction, and frame editing as appropriate for a given acquisition series. A diagnostic processor calculates a diagnostic value for the disc based upon a weighted factor set of criteria that uses MRS data extracted from the acquired and processed MRS spectra for multiple chemicals that have been correlated to painful vs. non-painful discs. A display provides an indication of results for analyzed discs as an overlay onto a MRI image of the lumbar spine.

Abstract: A powered surgical cutting and stapling instrument is disclosed. The instrument includes at least one sensor to measure at least one parameter associated with the instrument, at least one processor, and a memory operatively associated with the processor. The memory includes machine executable instructions that when executed by the processor cause the processor to monitor the at least one sensor over a predetermined time period and determine a rate of change of the measured parameter.

Abstract: A system includes multiple electrically-conductive channels and a processor. The processor is configured to receive, over the electrically-conductive channels, (i) respective first electric currents from a probe, which is within a body of a patient, via a plurality of first electrodes, which are attached to skin of the patient at a region of the body, and (ii) a second electric current from the probe via a second electrode, which is attached to the skin and is connected to one of the channels. The processor is further configured to ascertain respective first electric-current values of the first electric currents and a second electric-current value of the second electric current, and to calculate a position of the probe between the region and the second electrode, based on the first electric-current values and the second electric-current value. Other embodiments are also described.

Abstract: The disclosure relates to a vascular access device, comprising a vascular cannula having a catheter portion for insertion into a blood vessel such as a vein of a patient, and a fixing portion for fixing the vascular cannula to a skin of a patient. The fixing portion and/or a plaster used to fix the fixing portion to the skin comprises at least one local reception coil element for receiving magnetic resonance signals.

Abstract: The systems and methods described herein can advantageously allow users to discretely measure their exhaled breath in an easy, cost-effective and non-invasive manner. A handheld breath sensing system may be provided with a main housing, a first mouthpiece, a lid, a sampling chamber, a sensor and a microprocessor. The first mouthpiece may be configured to allow a user to exhale into the mouthpiece. The lid may be movable between an open position and a closed position. The sampling chamber may be in fluid communication with the first mouthpiece. The sensor may be in fluid communication with the sampling chamber and configured to measure at least one property of a user's breath. The microprocessor may be configured to process electronic signals from the sensor such that at least one volatile organic compound in the user's breath can be quantified and a resulting biomarker measurement provided to the user in near real-time.

Abstract: A sensor-based quantification and analysis system includes an input device including a plurality of sensors that generate an input based on a force. The input device also includes a transmission device that transmits force information based on the input. The system also includes an output device that receives the force information. A processing unit selects, for each of the plurality of sensors, one of a plurality of levels of a likelihood of tissue damage based on the force and a predetermined time period. Further, the output device includes a display that presents or logs the one of the plurality of levels of the likelihood of tissue damage for each of the plurality of sensors.

Abstract: A method of providing gait coaching is disclosed. Run data is received and stored regarding runs of a broad and diverse population of users, as well as a more narrow set of expert users. A gait metric model is developed for determining an ideal stride length or cadence based on pace and at least one physiological characteristic. Regression coefficients for at the model are determined based on a regression of the run data from the broad and diverse population of users. In contrast, a regression constant for the model is determined based on a regression of the run data from expert users. Using the model, an ideal stride length or cadence for a particular user on a particular run can be determined and utilized to provide useful monitoring, comparison, and feedback to the user regarding his or her stride length or cadence.

Abstract: The present invention relates to a device, system and method for detection of pulse and/or pulse-related information of a patient.

Abstract: Disclosed is sampling HF-QRS signals from a number of subjects (or derived values or features), and using e.g. deep learning-convolutional neural networks to find features or values which are (i) sufficiently similar for the same subject over all samples, yet (ii) sufficiently different among different subjects to allow identification. Also disclosed is finding signatures which are sufficiently stable over a particular period such that these signatures are within a deviation threshold, and then monitoring all subjects to be identified at least as often as the period used to establish the deviation threshold.

Abstract: A sleep position trainer (1) has a normal operational mode for alerting when a posture of the body detected by the position sensor (34) corresponds with an undesired body posture. The sleep position trainer further comprises a non-movement timer (t1) for timing a non-movement period of the user wearing the sleep position trainer. An output signal is send to an alert unit in case that a posture of the body detected by a position sensor (34) corresponds with a body posture when a threshold value of the non-movement timer (t1) of at least 15 minutes is exceeded.

Abstract: An action recognition system is illustrated. The action recognition system has an annular body, at least one light emitting unit, at least one light sensing unit and an action recognition module. The annular body is worn on a movable part of a user. One end of the light emitting unit is exposed on an inner side of the annular body, wherein the light emitting unit emits a first light beam illuminating at least a portion of the movable part. One end of the light sensing unit is exposed on the inner side of the annular body. The light sensing unit operatively senses a second light beam reflected by the at least portion of the movable part and generates a light sensing signal. The action recognition module is configured to operatively determine an action of the user according to the light sensing signal.

Abstract: Disclosed herein are examples of methods and systems for performing a calibration check of a personal hearing test system using a built-in calibration cavity, particularly for use by a non-expert user outside the clinical environment. The hearing test system includes a one or more earpieces. The hearing test system further includes a portable test unit having an acoustic calibration cavity for accommodating the earpiece at least partially therein. The acoustic calibration cavity may include an opening along an exterior surface of the portable test unit. The acoustic calibration cavity receives an acoustic calibration stimuli and the microphone provided within the acoustic calibration cavity produces a calibration signal input for measuring and performing a calibration check, or an automatic self-calibration.

Abstract: An apparatus for estimating blood concentration may include an optical sensor configured to emit light towards a skin surface of a user, and detect an optical signal reflected by the skin surface of the user, and a processor configured to select an interval-specific blood concentration estimation model, from among a plurality of interval-specific blood concentration estimation models, based on an interval selection indicator and estimate a blood concentration change or a blood concentration of an analyte using the selected interval-specific blood concentration estimation model and the detected optical signal.

Abstract: The subject invention provides sensor systems that can detect biomarkers related to wound healing (e.g., uric acid, adenosine, arginine and/or xanthine). In one embodiment, the subject invention pertains to materials and methods for monitoring biomarkers non-invasively in a wound and a biofluid (e.g., sweat) in the proximity of the wound, optionally, including other physiological fluids. Skin based, non-invasive enzymatic electrochemical biosensor on a wearable platform (e.g., sweat patch) that can evaluate the healing of wounds through assessment of its biomarker levels are provided. This non-invasive detection from physiologically biofluids can reduce or eliminate occlusion effects.

Abstract: Method and apparatus for providing an integrated analyte sensor and data processing unit assembly is provided.

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.