Patents Issued in April 28, 2020
  • Patent number: 10632432
    Abstract: A dispensing device, comprising a plurality of microfluidic pumps, microfluidic valves, and a microfluidic mixer chip, for receiving and mixing microfluidic amounts of a plurality of fluids having differing viscosities, is disclosed. The device includes a plurality of pathways for moving fluids from associated reservoirs to the microfluidic mixer chip. A mix controller controls the microfluidic pumps and valves so that the fluids, having different viscosities, can be accurately mixed at specified microfluidic amounts or volumes according to a specified microfluidic recipe, and the microfluidic mixture dispensed from the device. The device can be in communication with a software application implemented on a mobile compute device, such as a smartphone, and receive instructions for implementing the specified microfluidic recipe from the software application such that the operation of device components is at the direction of the software application executed on the mobile compute device.
    Type: Grant
    Filed: October 11, 2018
    Date of Patent: April 28, 2020
    Assignee: Altopa, Inc.
    Inventors: Matt Wilson, Jon Whalen, Todd Wilson, Pete Crawford, Scott Eric Liddle, Keith Gausmann, Jaysun Giesler, Nathan Thomas Luck, Nicole Kaylor Wicker, Jon Collette
  • Patent number: 10632433
    Abstract: A disposable material processing apparatus, useable as a bioreactor or fermenter, includes a hollow tank (101) and a mixing paddle (110) disposed within the interior of the tank and adapted to mix contents therein. The paddle may be isolated within a flexible sleeve (140). Various functional elements, such as a sparger, sensor, material extraction conduit, material addition conduit, and/or heat exchange element may be provided, and optionally arranged to travel with the paddle within the tank interior. Baffles may protrude into a mixing tank to enhance mixing. A tank and/or sleeve may comprise polymeric film materials.
    Type: Grant
    Filed: May 12, 2007
    Date of Patent: April 28, 2020
    Assignee: PALL LIFE SCIENCES BELGIUM BVBA
    Inventors: Tom Claes, Jean-Pascal Zambaux, Steven Vanhamel, Christophe Braet, Florence Bosco, Jose Castillo
  • Patent number: 10632434
    Abstract: An apparatus for accommodation and dispensing of miscible materials has an accommodation vessel having a lower region in the form of a truncated cone, with a lower discharge opening in the direction of gravity, and ha a mixing mechanism shaft disposed centrally in a mixing space, which shaft has at least one mixing mechanism that revolves in the accommodation vessel. The discharge opening is provided with a displacer apparatus that projects into the interior of the lower region of the accommodation vessel. The lower end of the mixing screw or mixing spiral of the mixing mechanism projects into the approximately V-shaped channel between the lower vessel wall and the displacer apparatus.
    Type: Grant
    Filed: February 17, 2015
    Date of Patent: April 28, 2020
    Inventor: Herbert Veit
  • Patent number: 10632435
    Abstract: Method and fluidized bed reactor for the production of granules, such as granules of urea or ammonium nitrate. The fluidized bed reactor comprises at least one granulation compartment with air inlets, and an air moving device downstream of the granulation compartment, e.g., downstream of at least one scrubbers. The air moving device is configured to draw air through said at least one air inlet into at least one granulation compartment.
    Type: Grant
    Filed: October 27, 2017
    Date of Patent: April 28, 2020
    Assignee: Yara International ASA
    Inventors: Jaap Voorhans, Luc Vanmarcke, André Kayaert
  • Patent number: 10632436
    Abstract: A hydrogen, lithium, and lithium hydride processing apparatus includes a hot zone to heat solid-phase lithium hydride to form liquid-phase lithium hydride; a vacuum source to extract hydrogen and gaseous-phase lithium metal from the liquid-phase lithium hydride; a cold zone to condense the gaseous-phase lithium metal as purified solid-phase lithium metal; and a heater to melt the purified solid-phase lithium metal in the cold zone and form refined liquid-phase lithium metal in the hot zone.
    Type: Grant
    Filed: May 11, 2017
    Date of Patent: April 28, 2020
    Assignee: Consolidated Nuclear Security, LLC
    Inventors: Sam W. Brown, Larry S. Spencer, Michael R. Phillips, G. Louis Powell, Peggy J. Campbell
  • Patent number: 10632437
    Abstract: The present invention relates to a shell-and-tube type reactor for reforming natural gas and a method for manufacturing syngas or hydrogen gas by using the same. According to the present invention, a shell-and-tube type reactor for reforming natural gas comprises a reaction catalyst for reforming natural gas, which is filled in a reactor shell; at least one tube for separating hydrogen; and a tube for an exothermic reaction or a tube type heat-exchanger for heating, which is disposed at the center of the reactor so as to have excellent operating efficiency and enable production of high-purity hydrogen and collection of carbon dioxide simultaneously along with a reaction.
    Type: Grant
    Filed: September 1, 2015
    Date of Patent: April 28, 2020
    Assignee: KOREA INSTITUTE OF ENERGY RESEARCH
    Inventors: Shin Kun Ryi, Jae Yun Han, Yong Seog Seo, Jung Hyun Lee
  • Patent number: 10632438
    Abstract: Contamination of fluidized bed-produced polycrystalline granules by phosphorus is reduced by employing as seals and/or packings, graphite containing <500 ppmw of phosphorus.
    Type: Grant
    Filed: October 21, 2015
    Date of Patent: April 28, 2020
    Assignee: WACKER CHEMIE AG
    Inventors: Gerhard Forstpointner, Dirk Weckesser
  • Patent number: 10632439
    Abstract: According to one or more embodiments disclosed herein, a system component of a fluid catalytic reactor system may include a catalyst separation section, a riser, and a reactor vessel. The catalyst separation section may include separation section walls defining an interior region of the catalyst separation section, a gas outlet port, a riser port, a separation device, and a catalyst outlet port. The riser may extend through the riser port of the catalyst separation section and include an external riser section and an internal riser section. The reactor vessel may include a reactor vessel inlet port, and a reactor vessel outlet port in fluid communication with the external riser section of the riser.
    Type: Grant
    Filed: May 31, 2017
    Date of Patent: April 28, 2020
    Assignee: Dow Global Technologies LLC
    Inventors: Matthew T. Pretz, Donald F. Shaw, Fermin Alejandro Sandoval
  • Patent number: 10632440
    Abstract: The invention concerns a CLC process, and its installation, producing high purity dinitrogen, comprising: (a) the combustion of a hydrocarbon feed by reduction of a redox active mass brought into contact with the feed, (b) a first step for oxidation of the reduced active mass (25) obtained from step (a) in contact with a fraction of a depleted air stream (21b), in order to produce a high purity stream of dinitrogen (28) and a stream of partially re-oxidized active mass (26); (c) a second step for oxidation of the stream of active mass (26) in contact with air (20) in order to produce a stream of depleted air and a stream of re-oxidized active mass (24) for use in step (a); (d) dividing the stream of depleted air obtained at the end of step (c) in order to form the fraction of depleted air used in step (b) and a fraction complementary to the depleted air extracted from the CLC.
    Type: Grant
    Filed: July 15, 2016
    Date of Patent: April 28, 2020
    Assignees: IFP ENERGIES NOUVELLES, TOTAL RAFFINAGE CHIMIE
    Inventors: Florent Guillou, Stephane Bertholin, Mahdi Yazdanpanah
  • Patent number: 10632441
    Abstract: The present invention relates to a method for preparing an aqueous or hydro-alcoholic colloidal solution of metal chalcogenide amorphous nanoparticles notably of the Cu2ZnSnS4 (CZTS) type and to the obtained colloidal solution. The present invention also relates to a method for manufacturing a film of large-grain crystallized semi-conducting metal chalcogenide film notably of CZTS obtained from an aqueous or hydro-alcoholic colloidal solution according to the invention, said film being useful as an absorption layer deposited on a substrate applied in a solid photovoltaic device.
    Type: Grant
    Filed: July 21, 2017
    Date of Patent: April 28, 2020
    Assignee: IMRA EUROPE SAS
    Inventors: Stephane Bourdais, Christophe Chone, Yan Cuccaro
  • Patent number: 10632442
    Abstract: A method and an apparatus for a large-scale production of monodisperse microspheres and biodegradable polymer-based drug delivery systems and design optimization method for the apparatus are provided. The method uses a plurality of microchips, each microchip having at least a first pathway, a second pathway and an outlet, wherein the first pathway and the second pathway merge at a cross point being one end of the outlet, and the method comprises preparing a polymer-phase solution including a degradable polymer and a water-phase solution including a surfactant, having the polymer-phase solution flow through the first pathway, having the water-phase solution flow through the second pathway, gathering a mixed solution flowing out of the outlet, and collecting the microspheres by filtering out the water-phase solution.
    Type: Grant
    Filed: October 20, 2017
    Date of Patent: April 28, 2020
    Assignee: INVENTAGE LAB INC.
    Inventor: Ju Hee Kim
  • Patent number: 10632443
    Abstract: The invention relates to microcapsules coated by a particular mixture of copolymers, which demonstrate a high rate of deposition when applied on a substrate. Those microcapsules can be used in several industries, in particular in perfumery and rinse-off applications. Perfuming compositions and perfumed consumer products comprising these microcapsules are also objects of the invention.
    Type: Grant
    Filed: June 28, 2016
    Date of Patent: April 28, 2020
    Assignee: Firmenich SA
    Inventors: Damien Berthier, Geraldine Leon, Glenn Verhovnik
  • Patent number: 10632444
    Abstract: A method for processing a biological material sample includes dispensing a sample into wells of an array tape from a sample plate, dispensing a reagent into the wells of the array tape from a reagent plate, and sealing the sample and the reagent in the array tape. The method further includes cooling the array tape and detecting biological material in the wells of the array tape.
    Type: Grant
    Filed: January 13, 2014
    Date of Patent: April 28, 2020
    Assignee: DOUGLAS SCIENTIFIC, LLC
    Inventors: Mark Whalen, Charles Gervais, Anthony Sanborn, Andrew Haug, Darren Cook, Satish Rai, Hans A. Mische, Stephen A. Judice, Daniel J. Shaffer
  • Patent number: 10632445
    Abstract: De novo synthesized large libraries of nucleic acids are provided herein with low error rates. Further, devices for the manufacturing of high-quality building blocks, such as oligonucleotides, are described herein. Longer nucleic acids can be synthesized in parallel using microfluidic assemblies. Further, methods herein allow for the fast construction of large libraries of long, high-quality genes. Devices for the manufacturing of large libraries of long and high-quality nucleic acids are further described herein.
    Type: Grant
    Filed: June 20, 2016
    Date of Patent: April 28, 2020
    Assignee: TWIST BIOSCIENCE CORPORATION
    Inventors: William Banyai, Bill James Peck, Andres Fernandez, Siyuan Chen, Pierre Indermuhle
  • Patent number: 10632446
    Abstract: An apparatus and method for economically copolymerizing ethylene and alpha-olefin by reusing reacting raw materials and solvents, comprising: a polymerization reactor where ethylene and alpha-olefin are supplied as reaction raw materials with a solvent, and the reaction raw materials are copolymerized in a solution state to produce a polymerization product comprising a dissolved ethylene and alpha-olefin copolymer; a unit for separating unreacted ethylene, alpha-olefin, low molecular weight oligomer and a polymer, including a flash tower for distilling and separating the unreacted ethylene and alpha-olefin from the polymerization product, and a stripper unit for distilling and separating the solvent and the low molecular weight oligomer having a molecular weight lower than the molecular weight of the ethylene and alpha-olefin copolymer in the polymerization product; and a solvent recovery unit for separating the low molecular weight oligomer from the separated low molecular weight oligomer and solvent to reco
    Type: Grant
    Filed: January 2, 2015
    Date of Patent: April 28, 2020
    Assignee: DAELIM INDUSTRIAL CO., LTD.
    Inventors: Jae Hoon Uhm, Jin Hun Ju, Hee Sun Bae, Joo Mi Yeo, Sah Mun Hong
  • Patent number: 10632447
    Abstract: Design, fabrication, and usage of a reactor are presented for synthesis of structured materials from a liquid-phase precursor by heating. The structured materials are particles, membranes or films of micro-porous molecular sieve crystals such as zeolite and meso-porous materials. The precursor solution and structured materials in the reactor are uniformly heated by a planar heater with characteristic heat transfer dimension in the range of 3 mm to 10 cm. A planar heater having width and length at least three times of the characteristic heat transfer dimension provides at least one surface of uniform temperature distribution for heating purposes. Heating is conducted over a temperature range of 20 to 300° C. The planar heater can be heated by electrical power of by thermal fluid.
    Type: Grant
    Filed: December 28, 2018
    Date of Patent: April 28, 2020
    Assignee: Molecule Works Inc.
    Inventor: Wei Liu
  • Patent number: 10632448
    Abstract: Various embodiments include a reactor comprising: a longitudinally extending reaction channel providing a flow path for a first reactant; a feed channel providing a flow path for a second reactant; multiple passage openings spaced apart from one another providing fluidic connecting between the feed channel and the reaction channel via respective partial streams for the second reactant; and a medium channel surrounding the reaction channel to bring a medium for exchange of heat with contents of the reaction channel and influencing a temperature of the reaction channel. The respective partial streams for the second reactant mix with the first reactant in the reaction channel to allow a chemical reaction of the first reactant and the second reactant.
    Type: Grant
    Filed: July 31, 2019
    Date of Patent: April 28, 2020
    Assignee: SIEMENS AKTIENGESELLSCHAFT
    Inventors: Alexander Jastram, Christoph Kiener
  • Patent number: 10632449
    Abstract: A method of mixing using a tubular reactor wherein process material continuously passes through the tubular reactor which is operating at predetermined reaction conditions. The tubular reactor is rotated through reciprocating arcs about the longitudinal axis of the tube as the process material passes therethrough. Static and/or dynamic mixers or agitators may be provided within the tubular reactor.
    Type: Grant
    Filed: October 30, 2013
    Date of Patent: April 28, 2020
    Assignee: Ashe Morris Ltd.
    Inventor: Robert Ashe
  • Patent number: 10632450
    Abstract: A metal-organic framework (MOF) structure comprising at least one metal ion and at least one multidentate organic ligand which is coordinately bonded to said metal ion, and a scaffold.
    Type: Grant
    Filed: March 26, 2018
    Date of Patent: April 28, 2020
    Assignee: NUMAT TECHNOLOGIES, INC.
    Inventors: Patrick Fuller, Mitchell Hugh Weston, William Morris, William Hoover
  • Patent number: 10632451
    Abstract: The present invention relates to a method for preparing superabsorbent polymer that has not only excellent permeability and absorption speed, but also minimized absorbency under pressure decrease rate, and superabsorbent polymer prepared thereby.
    Type: Grant
    Filed: July 11, 2016
    Date of Patent: April 28, 2020
    Assignee: LG Chem, Ltd.
    Inventors: Min Ho Hwang, Hye Mi Nam, Sang Gi Lee, Soo Jin Lee, Tae Hwan Jang
  • Patent number: 10632452
    Abstract: The invention relates to the field of cleaning the environment, and more particularly to a sorbent material for collecting petroleum and petroleum products, and to a method of producing the same. The method includes saturating a basalt fiber canvas with a hydrophobizing liquid and subsequently drying the same, wherein the basalt fibers of the canvas have a diameter of 0.2-2 microns and a density not exceeding 20-25 kg/m3; prior to saturation, the canvas is first fluffed using compressed air until a density of 12-15 kg/m3 is reached; the saturation using a hydrophobizing liquid is performed by introducing the hydrophobizing liquid into the pre-fluffed basalt fibers of the canvas in the form of aerosol particles via compressed air; and the subsequent drying of the saturated canvas is performed using compressed air, preferably at a temperature of 65° C.-75° C. The technical effect of invention is a simplified method with a broader field of application.
    Type: Grant
    Filed: February 19, 2016
    Date of Patent: April 28, 2020
    Assignee: GREEN OCEAN MALTA LIMITED
    Inventors: Shai Granovsky, Leonid Urievich Tsybulya, Vadim Urievich Manov
  • Patent number: 10632453
    Abstract: Methods, catalysts, and corresponding catalyst precursors are provided for performing dewaxing of diesel or distillate boiling range fractions. The dewaxing methods, catalysts, and/or catalyst precursors can allow for production of diesel boiling range fuels with improved cold flow properties at desirable yields. The catalysts and/or catalyst precursors can correspond to supported base metal catalysts and/or catalyst precursors that include at least two Group 8-10 base metals supported on the catalyst, such as a catalyst/catalyst precursor including both Ni and Co as supported metals along with a Group 6 metal (i.e., Mo and/or W). The support can correspond to a support including a zeolitic framework structure. The catalyst precursors can be formed, for example, by impregnating a support including a zeolitic framework structure with an impregnation solution that also includes a dispersion agent.
    Type: Grant
    Filed: February 22, 2018
    Date of Patent: April 28, 2020
    Assignee: ExxonMobil Research and Engineering Company
    Inventors: Chuansheng Bai, Paul Podsiadlo, Stephen J. McCarthy
  • Patent number: 10632454
    Abstract: A new aluminosilicate zeolite designated UZM-50, methods of making the zeolite, and its use as a catalyst in hydrocarbon conversion processes are described. This zeolite is represented by the empirical formula: M+mRrAl1-xExSiyOz where M is selected from the group consisting of hydrogen, sodium, potassium, magnesium, calcium or combinations thereof, R is the organic structure directing agent or agents derived from reactants R1 and R2 where R1 is an amine essentially incapable of undergoing pyramidal inversion and having 7 or fewer carbon atoms, and R2 is a dihaloalkane, and E is an element selected from the group consisting of gallium, iron, boron and mixtures thereof. UZM-50 has utility in various hydrocarbon conversion reactions such as conversion of an aromatic molecule to another aromatic molecule.
    Type: Grant
    Filed: December 28, 2017
    Date of Patent: April 28, 2020
    Inventors: Mark A. Miller, Christopher P. Nicholas, Melissa M. Galey, Mimoza Sylejmani, John Mowat, Collette Nicholas
  • Patent number: 10632455
    Abstract: A new family of highly charged crystalline microporous metallophosphate molecular sieves designated MeAPO-81 has been synthesized. These metallophosphates are represented by the empirical formula of: Rp+rA+mM2+xEyPOz where A is an alkali metal such as potassium, R is at least one quaternary ammonium cation of which one must be a cyclic diquaternary organoammonium cation such as N,N,N?,N?-tetramethyl-N,N?-butano-1,6-hexanediammonium, M is a divalent metal such as zinc and E is a trivalent framework element such as aluminum or gallium. The MeAPO-81 family of materials has the BPH topology. The MeAPO-81 family of materials is among the first MeAPO-type molecular sieves to be stabilized by combinations of alkali and organoammonium cations, enabling unique high charge density compositions. The MeAPO-81 family of molecular sieves has catalytic properties for carrying out various hydrocarbon conversion processes and separation properties for separating at least one component.
    Type: Grant
    Filed: September 6, 2018
    Date of Patent: April 28, 2020
    Inventor: Gregory J. Lewis
  • Patent number: 10632456
    Abstract: A process for producing an organic acid ester-type liquid is disclosed which is a process for removing an organic peroxide contained in an organic acid ester-type liquid which is a solvent of a resist for producing electronic parts or an organic acid ester-type liquid which is a rinsing liquid for producing electronic parts, which comprises contacting the organic acid ester-type liquid with a platinum group metal catalyst to remove the organic peroxide in the organic acid ester-type liquid, and a resist solvent for producing electronic parts or a rinsing liquid for producing electronic parts which comprises an organic acid ester-type liquid in which an organic peroxide contained therein has been removed by using the producing process and a peroxide value (POV) thereof is 2 mmoL/kg or less.
    Type: Grant
    Filed: June 28, 2016
    Date of Patent: April 28, 2020
    Assignee: MUSASHINO CHEMICAL LABORATORY, LTD.
    Inventors: Masakazu Tsukida, Hitoshi Takada
  • Patent number: 10632457
    Abstract: Provided herein are bi-metallic catalysts, methods of making, and uses thereof. In some embodiments, the bi-metallic catalyst contains two different metal catalysts that can be used in hydrocarbon metathesis reactions, in some embodiments, the methods of making the bi-metallic catalysts can include two steps utilizing a surface organometallic chemistry approach in which the two different metal catalysts are sequentially grafted onto a support.
    Type: Grant
    Filed: July 12, 2016
    Date of Patent: April 28, 2020
    Assignee: KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Jean-Marie Basset, Manoja K. Samantaray, Raju Dey, Edy Abou-Hamad, Santosh Kavitake
  • Patent number: 10632458
    Abstract: A compound honeycomb body comprising a first honeycomb section having a volume V1 and a second honeycomb section fluidly connected to the first honeycomb having a volume V2 is provided. The first honeycomb section comprises a low mass high porosity porous ceramic substrate. The second honeycomb section comprises a standard porous ceramic substrate. Wherein V1/V2 comprises a ratio in a range from about 50/50 to about 10/90.
    Type: Grant
    Filed: November 29, 2016
    Date of Patent: April 28, 2020
    Assignee: Corning Incorporated
    Inventors: Thorsten Rolf Boger, Willard Ashton Cutler, Ameya Joshi, Kunal Upendra Sakekar
  • Patent number: 10632459
    Abstract: Provided is a method for maintaining a preset air pressure of a low-pressure chamber. The method may comprise the steps of: measuring the inside air pressure of a low-pressure chamber; if the difference between the inside air pressure and a preset air pressure is the same or higher than a threshold value, adjusting the inside temperature of the low-pressure chamber by using a thermal conduction part disposed inside the low-pressure chamber; and by using a getter, making the difference to be below the threshold value by adsorbing or releasing molecules inside the low-pressure chamber according to the adjustment of the temperature.
    Type: Grant
    Filed: April 14, 2016
    Date of Patent: April 28, 2020
    Assignee: Korea Aerospace Research Institute
    Inventors: Hyok Jin Cho, Hee Jun Seo, Sung Wook Park, Guee Won Moon
  • Patent number: 10632460
    Abstract: A pipetting device has a pipetting channel extending along a channel path, in which a piston is accommodated to be movable along the channel path to change the pressure of a working gas that wets the piston on a dosing side facing the dosing liquid. The pipetting device includes a movement drive for driving the piston along the channel path and a control unit configured to operate the movement drive for pipetting a predetermined single dosing volume of less than 5 ?l with the piston moving in the pipetting direction and its dosing side end face sweeping over a pipetting volume which is not less than 1.4 times greater than the single dosing volume, and subsequently moving in a counter pipetting direction and its dosing side end face sweeping over a counter pipetting volume, wherein not more than 50 ms elapse between beginning control signals.
    Type: Grant
    Filed: July 26, 2016
    Date of Patent: April 28, 2020
    Assignee: Hamilton Bonaduz AG
    Inventors: Hanspeter Romer, Fridolin Gysel, Urs Lendenmann
  • Patent number: 10632461
    Abstract: According to one embodiment, a sealed chemical container has a bonding area where a flexible sheet-like member is firmly bonded onto a plate, and the bonding area defines a first compartment which can be swollen and an outflow passage which communicates with the first compartment via an opening. A first seal portion is weakly bonded onto the plate compared to the bonding area to define the first compartment to block communication between the first compartment and an outflow passage. The first seal portion is peeled off by an increase in internal pressure in the first compartment to allow communication between the first compartment and the outflow passage.
    Type: Grant
    Filed: September 28, 2017
    Date of Patent: April 28, 2020
    Assignee: Canon Medical Systems Corporation
    Inventors: Hiroaki Kushima, Nobuo Kawamura, Tetsuya Kuwabara, Sotaro Taki
  • Patent number: 10632462
    Abstract: A microfluidic device includes an integrated circuit and a first substrate layer having a first surface and a second surface. The first surface of the first substrate layer is connected to the integrated circuit. The first substrate layer is in fluid communication with the integrated circuit. The microfluidic device also includes a second substrate layer having a surface area substantially larger than that of the first substrate layer. The second substrate layer includes a first and second surface. The first surface of the second substrate layer is connected to the second surface of the first substrate layer. The second substrate layer includes a first fluid inlet. The second substrate layer is in fluid communication with the integrated circuit through the first substrate layer.
    Type: Grant
    Filed: September 15, 2015
    Date of Patent: April 28, 2020
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: David Issadore, Melaku Muluneh Woldermariam
  • Patent number: 10632463
    Abstract: In certain embodiments, the disclosure provides an inflatable bladder lid that configures with a cartridge configured for assay testing. The inflatable bladder provides substantially uniform pressure to the cartridge. The pressure is substantially distributed across the one or more regions of the cartridge to extend pressure over a wide cartridge surface. At least a portion of the bladder lid may comprise a flexible membrane material that inflates and stretches over at least a portion of the cartridge to conformally contact its first/top surface.
    Type: Grant
    Filed: July 26, 2017
    Date of Patent: April 28, 2020
    Assignee: ANCERA, LLC
    Inventor: Hur Koser
  • Patent number: 10632464
    Abstract: A microfluidic device includes an inlet port configured to receive a sample, a first reaction chamber fluidically coupled to the inlet port, a first pump fluidically coupled to the inlet port, a second pump fluidically coupled to a mixing chamber, a metering channel fluidically coupled to the first reaction chamber and to the mixing chamber, and one or more second reaction chambers fluidically coupled to the mixing chamber. The first pump is configured to move fluid from the inlet port to the first reaction chamber and from the first pump to the inlet port. The second pump is configured to move fluid from the second pump to the mixing chamber, from the first reaction chamber to the mixing chamber, and from the mixing chamber to the one or more second reaction chambers.
    Type: Grant
    Filed: February 27, 2018
    Date of Patent: April 28, 2020
    Assignee: ALERE SAN DIEGO, INC.
    Inventors: Alexander Schenk zu Schweinsberg, Austin Matthew Derfus, Justin Davidson, Karthikeyan Kumaravadivelu, Maulik Vinod Patel, Olaf Piepenburg, Catherine Jean Greenwood, Oliver Nentwich
  • Patent number: 10632465
    Abstract: The present invention relates to a contact-less priming system for loading a solution in a microfluidic device comprising: at least one microfluidic device, a pressure chamber configured to enclose said at least one microfluidic device, a pressurization unit fluidly connected to the pressure chamber and at least one closing member. The present invention also relates to a contact-less priming method for loading a solution in a microfluidic device.
    Type: Grant
    Filed: April 22, 2016
    Date of Patent: April 28, 2020
    Assignee: Stilla Technologies
    Inventors: Rémi Dangla, Étienne Fradet
  • Patent number: 10632466
    Abstract: The technology described herein generally relates to systems for extracting polynucleotides from multiple samples, particularly from biological samples, and additionally to systems that subsequently amplify and detect the extracted polynucleotides. The technology more particularly relates to microfluidic systems that carry out PCR on multiple samples of nucleotides of interest within microfluidic channels, and detect those nucleotides.
    Type: Grant
    Filed: November 27, 2019
    Date of Patent: April 28, 2020
    Assignee: HANDYLAB, INC.
    Inventors: Jeff Williams, Kerry Wilson, Kalyan Handique
  • Patent number: 10632467
    Abstract: A cartridge has a container with at least one well, protrusions distributed on the container base side, and a flat polymer film having a lower surface and a hydrophobic upper surface kept at a distance (d) to the container base side by the protrusions. The container and the film are reversibly attachable to a liquid droplet manipulation instrument so that the lower surface of the film abuts at least one electrode array of the instrument. The container enables displacement of at least one liquid droplet from a well onto the hydrophobic upper surface of the flat polymer film and above the electrode array. The liquid droplet manipulation instrument has a control unit with a voltage control and an electrode selector for individually selecting each electrode of the electrode array and for providing the selected electrode with a voltage.
    Type: Grant
    Filed: June 17, 2019
    Date of Patent: April 28, 2020
    Assignee: TECAN TRADING AG
    Inventor: Marc N. Feiglin
  • Patent number: 10632468
    Abstract: An apparatus configured for improving retention of non-adherent cells is disclosed. The apparatus includes a plate that includes a number of elements having a first surface energy arranged in an array with an overlay, on the plate, having a second surface energy. The first surface energy results in a hydrophilic surface and the second surface energy results in a hydrophobic surface. A diameter of the elements is at least 1 mm. A height of the overlay having the second surface energy, which results in a hydrophobic surface, is between 5% and 100% of the diameter of the elements. The apparatus also includes a wall circumferential to the plate. A method for performing multiple reactions with the apparatus is also disclosed.
    Type: Grant
    Filed: January 30, 2018
    Date of Patent: April 28, 2020
    Assignee: Curiox Biosystems Pte Ltd.
    Inventors: Namyong Kim, Siah Chong Cheong, Hanwen Melvin Lye, Mark Siew Peng Phong, Li Li, Teow Soon Seah
  • Patent number: 10632469
    Abstract: Embodiments of the invention provide a filter kit including filters for processing a biological sample. Some embodiments include a filter cap in a tube kit with a first tube containing a buffer solution and a second tube containing a lyophilized master mix. Some embodiments include a method of processing a sample using the kit including mixing a biological sample in a first tube with the buffer solution, positioning the filter cap in the first tube, positioning a second tube on the filter cap, flipping the first tube, the filter cap, and the second cap to filter the biological sample and buffer solution mixture with the filter cap as it flows from the first tube to the second tube. Some embodiments include structure enabling transfer of materials through inline flow between the tubes. Some further embodiments include integrated structure for sample pulverization with integrated buffer and lyophilized master mix.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: April 28, 2020
    Assignee: DOUGLAS SCIENTIFIC, LLC
    Inventors: Robert Hjelseth, Cory Hodgson, Andrew Bristow, Mark Baumgartner, David Sellnow, Cassie Keppel, John Steckelberg, Paul Newman
  • Patent number: 10632470
    Abstract: An apparatus for performing a thermocyclic process, such as amplifying DNA, includes a microfluidic chip with a channel formed therein and one or more thermal distribution elements disposed over portions of the chip. Each thermal distribution element is configured to distribute thermal energy from an external thermal energy source substantially uniformly over the portion of the chip covered by the thermal distribution element. The portion of the chip covered by the thermal distribution element thereby comprises a discrete temperature zone. Other temperature zones can be defined by other thermal distribution elements or by portions of the chip not covered by a thermal distribution element. The channel is configured so that a fluid flowing through the channel would enter and exit the different temperature zones a plurality of times, thereby alternately exposing the fluid to the temperature of each zone for a period of time required for the fluid to traverse the zone.
    Type: Grant
    Filed: August 7, 2017
    Date of Patent: April 28, 2020
    Assignee: Canon U.S.A., Inc.
    Inventors: Gregory A. Dale, Kenton C. Hasson, Shulin Zeng, Michele Stone
  • Patent number: 10632471
    Abstract: A device for processing feed material, with a housing enclosing a processing space in which a rotor rotatable about the axis of rotation is arranged. The rotor has a rotor disk at which circumference a plurality of axially disposed impact plates is arranged uniformly distributed. A coaxially arranged processing path surrounds the impact plates while maintaining a working gap. Via a material inlet, the device is fed in the axial direction with feed material centrally ending in the processing space, which upon deflection in the region of the rotor disk is fed in the radial direction to the working gap. To ensure complete and gentle processing of the feed material while maintaining its original taste, smell and color, the processing path is part of a basket rotating about the rotational axis.
    Type: Grant
    Filed: October 13, 2016
    Date of Patent: April 28, 2020
    Assignee: PALLMANN Maschinenfabrik GmbH & Co. KG
    Inventor: Hartmut Pallmann
  • Patent number: 10632472
    Abstract: A machine and a method for transporting a liner into a grinding mill body wherein the machine includes a housing for insertion through an opening of the grinding mill body. The housing has a first end, a second end and a conduit in communication with the first end and the second end, and a conveying device for conveying the liner along the conduit between the first and second ends.
    Type: Grant
    Filed: August 18, 2016
    Date of Patent: April 28, 2020
    Assignee: OUTOTEC (FINLAND) OY
    Inventors: Jeff Belke, Rory Soutar-Dawson
  • Patent number: 10632473
    Abstract: A granulator includes a rotary crushing blade for crushing an object to be processed that has been fed into a main body. A stationary granulating blade includes a plurality of small shearing blades below the rotary crushing blade. A movable granulating blade includes a plurality of shearing blades below the rotary crushing blade. The granulator includes an oscillating shaft pivotably supporting the movable granulating blade so as to be oscillatable in directions in which the movable granulating blade moves toward or away from the stationary granulating blade. A driving mechanism is provided for oscillating the oscillating shaft, in which the movable granulating blade is detachably fixed to a movable blade holder and the movable blade holder is detachably fixed to the oscillating shaft.
    Type: Grant
    Filed: December 24, 2015
    Date of Patent: April 28, 2020
    Assignee: KABUSHIKI KAISHA HARMO
    Inventor: Osamu Ito
  • Patent number: 10632474
    Abstract: The invention relates to a disintegrating device including a comb system (I), wherein the disintegrating device is formed by at least one disintegrating roller (1), rotatably mounted in a machine frame, with at least one disintegrating tool (2) arranged thereon, wherein the disintegrating device has at least one counter blade (3) that cooperates with the disintegrating tool (2), and including at least one base comb (II) on which the at least one counter blade (3) is arranged, and on which at least one sieve element (41) can be arranged as a component of a sieve device (4), wherein the sieve device (4) at least partially includes the disintegrating roller (1) in the intended application. According to the invention, the sieve element (41) is spring-mounted on the base comb (II).
    Type: Grant
    Filed: December 7, 2015
    Date of Patent: April 28, 2020
    Assignee: DOPPSTADT FAMILIENHOLDING GMBH
    Inventors: Johann Doppstadt, Horst Berger
  • Patent number: 10632475
    Abstract: A centrifuge (10), having a drive shaft (12), a rotor (40) mounted on the drive shaft (12) so as to be detachable axially in a removal direction (66), a quick-action closure (54) integrated in the rotor (40) and the drive shaft (12), which closure can be used to secure the rotor (40) relative to the drive shaft (12) in a removal direction (66), an abutment (50, 52) in the drive shaft (12) which is engaged by a locking member (46) of the rotor (40), at least one blocking element (76), which—when activated—fixes the rotor (40) relative to the drive shaft (12) and which acts between the locking member (46) of the rotor (40) and the abutment (50, 52) of the drive shaft (12), which quick-action closure (54) includes a force-transmitting element (58, 72).
    Type: Grant
    Filed: July 10, 2015
    Date of Patent: April 28, 2020
    Assignee: ANDREAS HETTICH GMBH & CO. KG
    Inventors: Andreas Hoelderle, Klaus-Guenter Eberle
  • Patent number: 10632476
    Abstract: A method for processing an initial liquid medium including cells in an initial concentration to obtain a product liquid medium including cells in a product concentration includes supplying the initial medium to a separator via a first supply system, separating the initial medium into various constituents including the product medium, extracting the product medium from the separator via a first outlet system, measuring a physical parameter related to the concentration of the cells in the initial medium using a sensor, and controlling at least one process parameter as a function of the physical parameter. During the step of separating the initial medium, a solution is supplied to the separator at a flow rate via a second supply system. The flow rate of the solution is determined based on the at least one process parameter, and is reduced when the concentration of the cells measured in the initial medium increases.
    Type: Grant
    Filed: July 6, 2018
    Date of Patent: April 28, 2020
    Assignee: Fresenius Kabi Deutschland GmbH
    Inventors: Artur Meisberger, Melanie Fahrendorff, Michael Brinkmann, Martin Biehl
  • Patent number: 10632477
    Abstract: A supercentrifuge with a non-intrusive device for the extraction of solids, the supercentrifuge comprising a chamber or rotor for the clarification of liquids and a piston located within the chamber passing through it in order to discharge the solids, the piston being driven in its outward travel along the chamber by the injection of a pressurised fluid which pushes the piston, in which the supercentrifuge has a pneumatic pumping system for the generation of vacuum to bring about return movement of the piston along the chamber.
    Type: Grant
    Filed: July 23, 2014
    Date of Patent: April 28, 2020
    Inventor: Marc Riera-Domenech
  • Patent number: 10632478
    Abstract: A dust collector includes a cylindrical housing forming an outer appearance of the dust collector; a primary cyclone formed inside the housing to cause a swirling flow to separate dust from air introduced into the housing; a secondary cyclone formed with axial inlet type cyclones to receive air and fine dust that have passed through the cyclone, and cause a swirling flow to separate the fine dust from the air; and a mesh provided at an outside surface the secondary cyclone to form a boundary between the primary and the secondary cyclones, wherein the axial inlet type cyclones includes a first group stacked in multiple stages, an inlet of which is arranged toward the mesh; and a second group provided on one side and the other side of the first group, respectively, an inlet and an outlet of which face a height direction of the dust collector.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: April 28, 2020
    Assignee: LG ELECTRONICS INC.
    Inventors: Kietak Hyun, Jungmin Ko, Sangchul Lee
  • Patent number: 10632479
    Abstract: A droplet generator apparatus and droplet generation method based on high aspect ratio induced droplet self-breakup are provided. The droplet generator apparatus includes a channel (1) and a nozzle (2) connected to the channel(1), and the aspect ratio of the channel (1) can be 3.0 or greater. The apparatus may further include a blocking rail (10) that is positioned in front of the nozzle (2), a supplying rail(9) that is positioned in front of the nozzle (2), and a supplying trench (8) formed in a space between the nozzle (2) and the supplying rail (9).
    Type: Grant
    Filed: May 20, 2016
    Date of Patent: April 28, 2020
    Assignee: The Hong Kong University of Science and Technology
    Inventors: Shuhuai Yao, Hongbo Zhou, Xiaonan Xu, Jianjie Lu
  • Patent number: 10632480
    Abstract: An adjustable shower device includes a water diversion valve body, a water inlet pipe, and more than one water outlet pipe. The water diversion valve body has a water inlet and more than one water outlet. The water inlet pipe is fixedly connected to the water inlet of the water diversion valve body. An inlet end of the more than one water outlet pipe is connected to the more than one water outlet. Because the water outlet pipe is a universal pipe that is a bendable metal shaping hose, the shower head on the water pipe can be swung to any height, which is more convenient for use.
    Type: Grant
    Filed: July 9, 2018
    Date of Patent: April 28, 2020
    Assignee: XIAMEN PRIME SHOWER CO., LTD.
    Inventor: Qin Yu
  • Patent number: 10632481
    Abstract: A hand-held dual flow dilution dispenser for precisely controlling the flow rate of water therethrough and for precisely injecting a liquid chemical into the water passing through the apparatus. The dispenser includes a water spool valve and a chemical spool valve with the spool valves being rotated between first and second positions. A handle is operatively connected to the first spool valve for rotating the first spool valve between the first and second positions. A linkage interconnects the handle and the second spool valve whereby rotational movement of the handle simultaneously causes rotation of the first spool valve and the second spool valve.
    Type: Grant
    Filed: November 8, 2019
    Date of Patent: April 28, 2020
    Inventor: Rodney Laible