Abstract: The present invention provides methods for dispensing or distributing a drug, particularly a potentially teratogenic drug, to a patient while minimizing the occurrence of an adverse side effect. In particular, the present invention provides methods for dispensing or distributing a drug containing topiramate to a patient in need of weight loss to minimize the occurrence of potential birth defects associated with the drug. Methods for providing training to prescribers on the potential risks associated with particular drugs are also disclosed.

Abstract: An automated medication dispensing system provides for triggering a medication administration message when an inferred event is detected for which a medication administration message is to be sent. The event might be the start, the beginning, or an anticipation of a start, of an eating event, detected by an event detection module from gestures of a user from a set of sensor readings. The message can be a signal to medication dispensing apparatus, and/or a reminder message to the user, an ancillary message to a caregiver, health professional, or others. The medication administration message might comprise a signal to an input of an insulin management system or an input of a meal-aware artificial pancreas. The events might also include a drinking event, a smoking event, a personal hygiene event, and/or a medication related event.

Abstract: An automated medication dispensing system provides for triggering a medication administration message when an inferred event is detected for which a medication administration message is to be sent. The event might be the start, the beginning, or an anticipation of a start, of an eating event, detected by an event detection module from gestures of a user from a set of sensor readings. The message can be a signal to medication dispensing apparatus, and/or a reminder message to the user, an ancillary message to a caregiver, health professional, or others. The medication administration message might comprise a signal to an input of an insulin management system or an input of a meal-aware artificial pancreas. The events might also include a drinking event, a smoking event, a personal hygiene event, and/or a medication related event.

Abstract: A dose management system receives a product characteristic for a product. The dose management system then associates the product with user, along with a smart monitor device that includes an embedded token. When the user thereafter installs a dose management application on a user device of the user, the dose management system receives the token, thereby authenticating the user device. The dose management system can additionally authenticate the user based on user access credentials of the user. Once the user device is authenticated, the user device, smart monitor device, and the dose management system remain in contact with each other, thereby permitting management of the product. For example, the dose management system can initiate a product refill, automatically or based on a user's request. The dose management system can also discern whether the user likely missed a dose (or not) and provide intelligent reminders to the user regarding the product.

Abstract: An automatic picking machine for pharmaceutical drug packages includes at least one storage rack, at least one storage and retrieval machine, a control apparatus for controlling the storage and retrieval machine, and a filling apparatus for successively filling each of a plurality of transport containers with a group of pharmaceutical drug packages corresponding to one order, wherein the filling apparatus includes a plurality of collection containers, first transport apparatuses, each having a transport channel for conveying the pharmaceutical drug packages towards the respective collection container, and a receiving apparatus for receiving a transport container to be filled at a filling location of the filing apparatus.

Abstract: Infusion systems including infusion devices and consumables and related operating methods are provided. An exemplary consumable component includes a housing, a reservoir contained within the housing, a pumping mechanism for dispensing a fluid from the reservoir, and a readable element associated with the housing. The readable element maintains calibration data characterizing a relationship between delivery of the fluid and actuation of the pumping mechanism.

Abstract: Collision avoidance and postural stability adjustment may provide an effective dual task paradigm to interpret the effect of proprioceptive adaptation on balance control. However, conventionally tasks are physical tasks performed under supervision in specific set up environments. Implementations of the present disclosure provide methods and systems for interpreting neural interplay involving proprioceptive adaptation in a lower limb during a dual task paradigm. The disclosed method provides a better interpreting of the neuronal mechanisms underlying adaptation and learning of skilled motor movement and to determine the relationship of lower limb proprioceptive sense and postural stability by simulating integration of a Single Limb Stance (SLS) functionality test for postural stability and a single limb collision avoidance task, in an adaptive Virtual Reality (VR) environment provided to a subject.

Abstract: This disclosure relates to analyzing effect of a secondary cognitive load task on a primary executive task. Human random sequence generation is a marker to study cognitive functions and inability to generate random sequences (RS) can reveal underlying impairments. Traditionally, ‘call out’ or ‘write down’ procedures are used to obtain human generated numbers, wherein short term memory and number of previously generated entities visible to a subject plays a major role. Also precise trial-wise or response-wise analysis may not be possible. In the present disclosure, the human generated random numbers are digitized into RS and a cognitive load (CL) inducing task is imposed on the executive task. The CL demanding task disrupts randomization performance. Deviation from randomness, load index based on gaze data and deviation from pupillometry data of healthy subjects are provided as indicators of an interference effect imposed by the CL and thereby indicative of underlying impairments.

Abstract: A method for facilitating selection, by a healthcare facility, of a physician from a plurality of physicians to provide interpretation of an imaging study, is provided. The method includes receiving physician credentials from at least one physician, receiving, from the healthcare facility, an imaging study and a request for interpretation of the imaging study, the request including physician selection criteria, providing access to the imaging study and the request for interpretation to qualified physicians whose credentials match the physician selection criteria, receiving an interpretation of the imaging study from those qualified physicians that have accepted the request for interpretation, comparing the physician credentials to the physician selection criteria, and selecting an imaging study interpretation from the received imaging study interpretations based on the comparing of the physician credentials to the physician selection criteria.

Abstract: An information processing apparatus includes an acquisition unit, a search unit, and a display control unit. The acquisition unit acquires a comparison image generated using a first examination image and a second examination image which are acquired by imaging a subject at different times/dates from each other. The search unit searches for clinical practice infonnation about a clinical practice perfonned on the subject during a period defined by a first examination date, at which the first examination image is acquired, and a second examination date, at which the second examination image is acquired. The display control unit displays the comparison image and the searched clinical practice information on a display unit.

Abstract: Provided are an information processing apparatus, an information processing method, and a program capable of accumulating appropriate relearning data. An information processing apparatus includes an input unit that inputs input data to a learned model acquired in advance through machine learning using learning data, an acquisition unit that acquires output data output from the learned model through the input using the input unit, a reception unit that receives correction performed by a user for the output data acquired by the acquisition unit, and a storage controller that performs control for storing, as relearning data of the learned model, the input data and the output data that reflects the correction received by the reception unit in a storage unit in a case where a value indicating a correction amount acquired by performing the correction for the output data is equal to or greater than a threshold value.

Abstract: The present disclosure provides a tissue density analysis system. The system includes an acquisition module configured to obtain image data and tissue density distribution data; a display module configured to display the obtained tissue density distribution data in one or more charts; a processing module configured to adjust the tissue density distribution data displayed in the one or more charts; and a storage module configured to store the image data, the tissue density distribution data and an instruction.

Abstract: A medical image processing apparatus for allocating at least two medical imaging processes to a plurality of assignable processing resources is provided. The plurality of assignable processing resources is allocated by the medical image processing apparatus based on resource information of the plurality of assignable processing resources. The medical image processing apparatus includes circuitry configured to acquire medical image processing content, from medical equipment, to be processed according to the at least two medical imaging processes prior to display on a display device connected to a surgical operating room network. The circuitry is configured to acquire the resource information of the plurality of assignable processing resources, and allocate each of the at least two medical imaging processes to a different one of the plurality of assignable processing resources based on the resource information of the plurality processing resources and the medical image processing content.

Abstract: A medical monitoring system extracts characteristic information for one or more medications from an image of the one or more medications on an uncontrolled background, the image being taken by a client device associated with a user of the medical monitoring system. The medical monitoring system determines prescription information associated with a medication, of the one or more medications, using the extracted characteristic information and a medication database, the medication database containing mappings between prescription information and characteristic information for a plurality of medications. The medical monitoring system provides a portion of the prescription information to the client device.

Abstract: The present disclosure provides a system that may receive first sensor data associated with first multiple measurements of multiple components of multiple medical systems; may receive filter information from first user input; may search, based at least on the filter information, the first sensor data to determine report data; may provide, via a graphical user interface, the report data to a user; may receive second user input that indicates one or more issues associated with at least one of the multiple medical systems; may determine one or more thresholds based at least on the second user input; may receive second sensor data associated with second multiple measurements of the multiple components of the multiple medical systems; and may determine, based at least on the one or more thresholds, at least one of the one or more issues associated with at least one of the multiple medical systems.

Abstract: A system for communication of data is provided. The system includes a medical device. A data consuming device is positioned at a first network layer. An edge communication device is positioned at a second network layer. The edge communication device is in communication with the medical device to receive data from the medical device. The edge communication device has a profile. The profile defines a data format for the data and a communication path for transmitting the data between the network layers. A gateway device is configured to route the data from the edge communication device to the data consuming device via the communication path. The edge communication device is also configured to modify the data format to correspond to the data consuming device and to format the data according to the data format.

Abstract: A method for managing or remotely monitoring chronic medical conditions (e.g., chronic respiratory conditions) of a plurality of patients includes, at one or more processors, receiving a plurality of bodily metrics associated with each of the plurality of patients over one or more remote communication links (e.g., an automated phone system), characterizing the severity of the medical condition for each patient based on the plurality of bodily metrics associated with the patient, and transmitting a programmed alert to a medical care provider for at last one patient having a medical condition characterized as having a threshold level of severity.

Abstract: The present disclosure relates to systems and methods for integrating a globally secure communications network with stored medical diagnostics. In one example, the system may include at least one memory storing instructions and at least one processor configured to execute the instructions. The instructions may include instructions to receive a request for a medical diagnostic; verify that the request originates from a location within an approved area; verify credentials of a user that originated the request; send the medical diagnostic to the user; receive, from the user, an identification of a recipient separate from the user; verify that the recipient originates from a location within an approved area; verify credentials of a user that originated the request; and in response to receiving the identification, send the medical diagnostic to the recipient.

Abstract: A method and system for determining a composite post-test likelihood that a patient has a medical condition using an iterative Bayesian analysis of test information and test results for multiple tests. Multiple medical conditions can be assessed and results viewed simultaneously, including assessments performed based on hypothetical tests and test results. Such assessment may help guide a clinician to selecting tests and/or treatment that are particularly relevant to a patient's medical condition diagnosis.

Abstract: For patients who exhibit or may exhibit primary or comorbid disease, pharmacological phenotypes may be predicted through the collection of panomic data over a period of time. A machine learning engine may generate a statistical model based on training data from training patients to predict pharmacological phenotypes, including drug response and dosing, drug adverse events, disease and comorbid disease risk, drug-gene, drug-drug, and polypharmacy interactions. Then the model may be applied to data for new patients to predict their pharmacological phenotypes, and enable decision making in clinical and research contexts, including drug selection and dosage, changes in drug regimens, polypharmacy optimization, monitoring, etc., to benefit from additional predictive power, resulting in adverse event and substance abuse avoidance, improved drug response, better patient outcomes, lower treatment costs, public health benefits, and increases in the effectiveness of research in pharmacology and other biomedical fields.

Abstract: Systems and methods are disclosed for determining a patient risk assessment or treatment plan based on emboli dislodgement and destination. One method includes receiving a patient-specific anatomic model generated from patient-specific imaging of at least a portion of a patient's vasculature; determining or receiving a location of interest in the patient-specific anatomic model of the patient's vasculature; using a computing processor for calculating blood flow through the patient-specific anatomic model to determine blood flow characteristics through at least the portion of the patient's vasculature of the patient-specific anatomic model downstream from the location of interest; and using a computing processor for particle tracking through the simulated blood flow to determine a destination probability of an embolus originating from the location of interest in the patient-specific anatomic model, based on the determined blood flow characteristics.

Abstract: The present application is directed to systems and methods providing a pathway configurable and executable via a pathway engine on a device. A device may establish a pathway configured via a pathway engine to execute on the device to monitor data points of a user and to generate actions based on monitoring of the data points. A monitor of the pathway engine may monitor data points of the user received by the device. The monitor may compare each value of the data points to the expected value and the predetermined threshold specified for the trigger condition. The pathway, based on the comparison, may determine that the trigger condition has been triggered. The pathway, responsive to the triggering of the trigger condition, may initiate an alert to identify the trigger condition and execution of the action specified by the pathway.

Abstract: Disclosed is a system and method for predictive risk assessment and intervention including a risk assessment unit that receives survey data from a remotely connected survey device. The survey data comprises information about the social and cultural environment of one or more members of a risk population, including the member's perceptions of their social and environmental factors, the member's demographic data, and optionally publicly available data associated with the member's geographic environment.

Abstract: A method and apparatus receive an identifier and determining, from the identifier, a particular patient and a related party. The method and apparatus further determine a contact method for the related party and sending, to the related party via the contact method, a request for healthcare information for the particular patient. The method and apparatus even further comprise receiving the requested healthcare information from the related party.

Abstract: An immutable system of records for achieving compliance in IoT/Control systems in order to thereby provide the regulator with a centralized immutable system of records, is disclosed herein. A blockchain based immutable record management module configured in association with a plurality of control systems associated with a plurality of devices/systems in a heavily regulated industry environment wherein the blockchain based immutable record management module receives and manages a plurality of immutable records from plurality of control systems associated with a plurality of devices/systems in a heavily regulated industry environment. The blockchain based immutable record management module further securely presents the immutable records to the regulators in order thereby enable the industry to inject undisputed facts to the regulators or the regulation authorities.

Abstract: Neutron shielding for the central column of a tokamak nuclear fusion reactor. The neutron shielding comprises an electrically conductive neutron absorbing material. The neutron shielding is arranged such that the electrically conductive neutron absorbing material forms a solenoid for the initiation of plasma within the tokamak.

Abstract: A method of removing, from a fusion power reactor, a tile that comprises a tile-support tube, which is attached to a back portion of the tile and which comprises a coolant channel that is configured in a horizontal orientation, comprises rotating the tile, which is installed in a locked orientation in a manifold channel of a first wall of the fusion power reactor, until the tile is in an install/remove orientation. The method further comprises grasping, with a removal tool, the tile-support tube. The method additionally comprises lifting the tile away from the first wall of the fusion power reactor with the removal tool such that the tile is completely removed from the manifold channel of the first wall of the fusion power reactor.

Abstract: The power plant system includes a molten salt reactor assembly, a thermocline unit, phase change heat exchangers, and process heat systems. The thermocline unit includes an insulated tank, an initial inlet, a plurality of zone outlets, and a plurality of gradient zones corresponding to each zone outlet and being stacked in the tank. Each gradient zone has a molten salt portion at a portion temperature corresponding to the molten salt supply from the molten salt reactor being stored in the tank and stratified. The molten salt portions at higher portion temperatures generate thermal energy for process heat systems that require higher temperatures, and molten salt portions at lower portion temperatures generate thermal energy for process heat systems that require lower temperatures. The system continuously pumps the molten salt supply in controlled rates to deliver the heat exchange fluid supply to perform work in the corresponding particular process heat system.

Abstract: A VVER-1000 nuclear fuel assembly having a modified bottom nozzle with chamfers at the upper edge of the frustoconical transition from a hexagonal upper section of the nozzle to the lower circular end that mounts on a lower core support.

Abstract: An electro-technical device includes a first housing portion electrically isolated from a second housing portion with a point source being disposed within the first housing portion. A movable conductor is connected to the first portion and is responsive to an electric field generated by the point source to cause the movable conductor to contact the second housing portion to complete a circuit and send out a control signal.

Abstract: Clamps can be secured to a slip joint and limit flow through the same by seating on a diffuser axially regardless of wear and damage in the slip joint. An extension from the clamp seats to the inlet mixer. These extensions can be adjusted from outside the clamp to achieve an individual preload or flow limitation through the slip joint. The extension may be an O-ring or other shape. A biasing drive may connect to and move the extension from an outside surface of the clamp. The biasing drive may include a threaded cap in an outer groove that is linked to a plunger via a spring. Clamps are fabricated of materials that maintain their physical properties when exposed to an operating nuclear reactor environment and may be relatively rigid and resilient metals.

Abstract: A nuclear reactor in one embodiment includes a cylindrical body having an internal cavity, a nuclear fuel core, and a shroud disposed in the cavity. The shroud comprises an inner shell, an outer shell, and a plurality of intermediate shells disposed between the inner and outer shells. Pluralities of annular cavities are formed between the inner and outer shells which are filled with primary coolant such as demineralized water. The coolant-filled annular cavities may be sealed at the top and bottom and provide an insulating effect to the shroud. In one embodiment, the shroud may comprise a plurality of vertically-stacked self-supported shroud segments which are coupled together.

Abstract: Methods and devices for detecting and quantifying water vapor concentration in spent nuclear fuel rods undergoing drying processes for safe storage purposes.

Abstract: A detector assembly for measuring flux in a nuclear reactor core includes a plurality of self-powered in-core detector arrangements each for measuring flux at a different one of a plurality of axial locations in the nuclear reactor core, and an assembly connector configured to be connected to a power plant connector. The assembly connector includes a plurality flux signal terminals each connected to one of self-powered in-core detector arrangements. At least one of the self-powered in-core detector arrangements comprises a set of at least two self-powered in-core detectors for measuring flux at a same one of the axial locations in the nuclear reactor core. Each of the at least two self-powered in-core detectors includes a sheath, a detector material section inside the sheath, an insulator between the sheath and the detector material, and a flux signal output line. The flux signal output lines of the at least two self-powered in-core detectors are joined together.

Abstract: An electro-technical device includes a circuit including a coil connected to a voltage source for receiving a predetermined current therefrom and connected to an output device. The circuit includes a breakable junction and a photodiode for receiving a light signal from a fiber optic cable. The photodiode receives a light signal from a sensor. A permanent magnet includes a pole end opposing a common pole end of the coil, wherein when the coil receives an increased current from the photodiode, the coil creates an magnetic flux that repels against the common pole of the permanent magnet in order to cause the breakable junction to break and disrupt a connection between the voltage source and the output device.

Abstract: An electro-technical device includes a first coil connected to a first sensor for receiving a current therefrom representative of a sensed condition, the first coil being anchored at first and second ends. A second coil is connected to a second sensor for receiving a current therefrom representative of a sensed condition, the second coil being anchored at first and second ends and being adjacent to the first coil. When the first and second coils receive an increased current from the first and second sensors, the first and second coils each create a magnetic flux that repel one another in order to cause at least one of the coils to break so that a shutdown signal can be sent.

Abstract: An electro-technical device, includes an input electrical connection supplied with an input signal and electrically isolated from an output electrical connection. A bar magnet is pivotally mounted on a pedicel between the input electrical connection and the output electrical connection. A pair of coils disposed on opposite sides of the bar magnet and each being supplied with an electronic signal from a sensor, the bar magnet being responsive to an electromagnetic filed generated by the pair of coils to cause the bar magnet to contact the input electrical connection and the output electrical connection and complete a circuit and send out a control signal.

Abstract: A mounting apparatus for a shielding system for customized shielding of a patient or an operator from radiation. The shielding system is mounted on a rail of a table used for interventional medical procedures comprising a longitudinal rail edge. In use, the mounting apparatus is slidably engaged to a rail by mating a t-shaped groove to the rail. Extending from the mounting apparatus is one or more movable rods from which protective radio-opaque curtains are suspended.

Abstract: The disclosure provides a collimator assembly, comprising at least at least two collimators configured to be moveable relative to each other such that the collimator assembly is switchable between at least two collimation modes; in respective collimation modes, the at least two collimators are superposed with each other in a thickness direction of the collimator assembly, such that the collimator assembly presents different combined patterns for collimating and shielding rays incident onto the collimator assembly and that the collimator assembly has corresponding ray shielding thickness for effectively shielding rays.

Abstract: Provided is an electric wire structure including a copper (Cu) electric wire extending in a direction; and a graphene coating layer formed on an outer portion of the Cu electric wire to surround the Cu electric wire, wherein the Cu electric wire includes Cu having a purity of 99.9% or greater.

Abstract: An electrical conductor includes: a first conductive layer including a plurality of ruthenium oxide nanosheets, wherein at least one ruthenium oxide nanosheet of the plurality of ruthenium oxide nanosheets includes a halogen, a chalcogen, a Group 15 element, or a combination thereof on a surface of the ruthenium oxide nanosheet.

Abstract: The disclosure describes a method of purifying a self-healing fluid (SHF) comprising a drying oil and dielectric fluid. The method comprises (a) filtering the SHF through an absorbent material; and (b) subsequently filtering the SHF through a micropore filter system.

Abstract: An insulated electric wire includes a linear conductor and an insulating film disposed to surround the periphery of the conductor. The insulating film includes a polyimide layer formed of a polyimide that has a molecular structure including a PMDA-ODA-type repeating unit A and a BPDA-ODA-type repeating unit B, the mole fraction [B×100/(A+B)] (% by mole) represented by the percentage of the number of moles of the repeating unit B to the total number of moles of the repeating unit A and the repeating unit B being 25% or more by mole and 95% or less by mole. The polyimide layer has a plurality of pores. The pores occupy 5% or more by volume and 80% or less by volume of the polyimide layer.

Abstract: A submarine power cable having: a power core including a conductor, wherein the conductor has a conductor joint in a joint region of the power core, a main armor layer including a plurality of main armor wires arranged around the power core and extending in the axial direction of the power core, and a joint reinforcement armor layer including a plurality of joint reinforcement armor wires axially locked relative to the main armor wires, wherein the joint reinforcement armor layer is provided only in the joint region and arranged layered with the main armor layer, the joint reinforcement armor layer and the main armor layer thereby forming a dual-layer armor only in the joint region.

Abstract: A rodent repellent cable has an outer protective jacket for housing the cable's internal components. The internal components include at least a means for facilitating transmission of electrical current or data, and a repellent bonded to at least one component of the cable. The means for facilitating transmission of electrical current or data include, but are not limited to, wires and optical fibers. The cable may include additional internal components, such as one or more separators and a sheath. The repellent is configured to repel rodents, based on a negative olfactory stimulus when the rodents are subjected to the repellent. This will deter rodents from chewing on wire or cable containing the repellent, which will significantly reduce the incidence of fires of undetermined origin and rodent-inflicted damage to wiring systems universally.

Abstract: Protective jackets for cable comprise: (A) an exterior layer (1) free of a pest repellant, and (2) having external and internal facial surfaces; (B) an inner layer (1) having a Shore D hardness of equal to or greater than (?) 63, (2) comprising a pest repellant, and (3) having two facial surfaces; and (C) optionally, a tie layer in contact with the internal facial surface of the exterior layer and a facial surface of the inner layer.

Abstract: The present invention provides an identifiable armored cable sheath. In accordance with an aspect of the present invention, there is provided an identifiable armored cable sheath comprising: an armored cable sheath having an outer surface, and a visual indicia applied on the outer surface of the cable sheath in a patterned arrangement, wherein the visual indicia possesses visibility features in low light. Another aspect of the present invention provides a method of making an identifiable armored cable sheath comprising: providing an armored cable sheath, and applying a visually distinctive tape to the outer surface of the sheath in a patterned arrangement.

Abstract: Fluidic channels and pumps for active cooling of cables are described. One cable assembly includes a conductor having a length between a first end of the cable and a second end of the cable and a fluidic channel structure that at least partially surrounds the conductor along the length of the conductor. A first pump connector is coupled to a first end of the fluidic channel structure and a second pump connector is coupled to a second end of the fluidic channel structure. Motion of liquid metal, when pumped through the fluidic channel structure, distributes heat away from the conductor.

Abstract: A tension relief for supply lines and a block-like clamping part therefor, which has a lateral surface designed as a clamping surface. The clamping surface of the clamping part is formed at least in one clamping portion by an elastic wall, which is delimited on the side facing away from the clamping surface by a cavity structure, which is formed by additional walls. The clamping part can be variedly used without modification on certain line diameters, in particular in a tension relief of a cable carrier or also in a connector housing.

Abstract: In one embodiment, an overvoltage protection device may include a metal oxide varistor (MOV) having a first surface and a second surface; a semiconductor substrate having a first outer surface and a second outer surface and comprising a semiconductor crowbar device comprising a plurality of semiconductor layers arranged in electrical series to one another, the semiconductor substrate being disposed on a first side of the metal oxide varistor; a conductive region disposed between the second surface of the MOV and the first outer surface of the semiconductor substrate; a first electrical contact disposed on the first surface of the MOV; and a second electrical contact disposed on the second outer surface of the semiconductor substrate.