Patents Issued in May 14, 2020
  • Publication number: 20200146946
    Abstract: A powder cosmetic provides an excellent finish and has an excellent usability while maintaining a hiding power, and exhibits an excellent capacity to be more transmissive of light in long wavelength regions (selective red light transmission capacity). The titanium dioxide powder is particles in which the apparent average particle diameter is 100 nm or more and less than 500 nm, the average crystallite diameter measured by x-ray diffraction is 15-30 nm, the specific surface area of 10-30 m2/g, and a ratio between the long diameter and short diameter of the shape (long diameter/short diameter) of 1.0-2.5, and the particles have a shape in which radially projecting needle-shaped projections are aggregated. The powder cosmetic incorporates the titanium dioxide powder.
    Type: Application
    Filed: May 29, 2018
    Publication date: May 14, 2020
    Applicant: SHISEIDO COMPANY, LTD.
    Inventors: Hideo HATA, Motoharu KIMURA
  • Publication number: 20200146947
    Abstract: The present invention relates to a cosmetic composition for a leave-on type mask sheet including a fluorinated compound and saponin as a self-foaming agent. The cosmetic composition for a leave-on type mask sheet includes a fluorinated compound and saponin as a self-foaming agent, and thus can provide a cleansing effect, such as an effect of removing sebum or waste. In addition, since the cosmetic composition includes saponin instead of a chemical surfactant, it can reduce side effects, such as skin irritation, alleviate inconvenience of washing-off after using the mask sheet, and improve a moisturizing effect by virtue of elimination of the washing-off procedure.
    Type: Application
    Filed: March 19, 2018
    Publication date: May 14, 2020
    Inventors: Chan Gu KIM, Ho-Yeol KIM, Yoon Nam JO, IL Rang LEE, Ja Yoon KOO, Myeong Sam PARK
  • Publication number: 20200146948
    Abstract: Provided is a polyether-based urethane foam for impregnating a cosmetic composition. The polyether-based urethane foam has excellent touch feel, portability and stability.
    Type: Application
    Filed: January 17, 2020
    Publication date: May 14, 2020
    Applicant: AMOREPACIFIC CORPORATION
    Inventors: Kyung Nam KIM, Jung Sun CHOI, Min Kyung SHIM, Kyung Ho CHOI, Yeong Jin CHOI
  • Publication number: 20200146949
    Abstract: Disclosed are UV-protective compositions comprising swelled polymer matrix macroparticles comprising a thermoplastic polymer swelled with at least one swelling agent, and a plurality of nanoparticles of an inorganic UV-protective agent comprising at least one solid inorganic crystal and a dispersant associated with the crystal, wherein the inorganic nanoparticles are dispersed and embedded in the swelled polymer matrix macroparticles. Method of preparation and uses of such compositions are also provided.
    Type: Application
    Filed: January 13, 2020
    Publication date: May 14, 2020
    Inventors: Benzion LANDA, Sagi ABRAMOVICH, Snir DOR
  • Publication number: 20200146950
    Abstract: An aerosol hairspray product includes a pressurisable container having a propellant and a container wall which encloses a reservoir, a hairstyling formulation having from 20 wt % to 75 wt % alcohol, by total weight of the hairstyling formulation and propellant and from 1.0 wt % to wt % hairstyling polymer, by total weight of the hairstyling formulation and propellant, and a spraying device attached to the pressurisable container and having a valve and an actuator. The reservoir is configured to store the hairstyling formulation. The valve has a spring means, a valve body having a stem, a restricted tail piece (RTP) having a first diameter of from 0.1 mm to 2.5 mm, and a vapour phase tap (VPT) having a second diameter of from 0.1 mm to 1.5 mm. The actuator has a main spray channel and communicates with an insert.
    Type: Application
    Filed: October 11, 2017
    Publication date: May 14, 2020
    Applicant: Conopco, Inc., d/b/a UNILEVER
    Inventors: Gillian BROWN, Laura FRANKLIN, Llyr Glyndwr GRIFFITHS, Leslie Joseph Luke JOINSON, Johnathan Douglas William SMITH, Paul James SMITH
  • Publication number: 20200146951
    Abstract: An emulsion composition has excellent emulsion stability. The emulsion composition has excellent emulsion stability contains water, an oily component, gum ghatti, and saponin, in which a content of the saponin is 0.05 to 30 parts by mass based on 100 parts by mass of the gum ghatti.
    Type: Application
    Filed: April 27, 2018
    Publication date: May 14, 2020
    Inventors: Takaaki ITO, Shunsuke KINOSHITA, Ryo MARUYAMA
  • Publication number: 20200146952
    Abstract: Provided is a cosmetic composition including organic-inorganic composite particles for blocking near-infrared rays. When the cosmetic composition for blocking near-infrared rays according to the present disclosure is applied to skin, light in the near-infrared region may be significantly blocked. The cosmetic composition may be used as a multifunctional product in combination with a UV-blocking material to block a wide range of wavelengths adversely affecting the skin, thereby preventing skin aging.
    Type: Application
    Filed: November 30, 2017
    Publication date: May 14, 2020
    Applicants: COSMAX INC., IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY)
    Inventors: Su Ji KIM, Jun Bae LEE, Chun Ho PARK, Youn Joon KIM, Kweon Jong YOO, Myeong Sam PARK, Eun Chul CHO, Seong Uk KIM, Min Gyu KIM, Nu Ri HAN
  • Publication number: 20200146953
    Abstract: Disclosed is a liquid concentrate which includes a) one or more aromatic alcohols, b) one or more specific organic acids or salts thereof and c) octenidine dihydrochloride. The liquid concentrate is used for preserving pharmaceutical (primarily dermatological) or cosmetic products.
    Type: Application
    Filed: January 13, 2020
    Publication date: May 14, 2020
    Inventors: Wolfgang BEILFUSS, Ralf GRADTKE, Stefan SAKULOWSKI, Klaus WEBER
  • Publication number: 20200146954
    Abstract: The invention related to high glycerol compositions comprising blends of alkyl isethionate and alkyl taurate. Selecting specific ratios of isethionate to taurate allows preparation of high glycerol liquids while minimizing amphoteric, all while retaining clear, isotropic liquid.
    Type: Application
    Filed: May 31, 2018
    Publication date: May 14, 2020
    Applicant: Conopco, Inc., d/b/a UNILEVER
    Inventors: Joseph Oreste CARNALI, Rajendra Mohanlal DAVE
  • Publication number: 20200146955
    Abstract: A hair conditioner composition with a gel network that can contain a fatty alcohol and a cationic surfactant having a chloride counterion. The gel network composition can contain a uniform lamellar structure that comprises all vesicles or mostly vesicles.
    Type: Application
    Filed: November 8, 2019
    Publication date: May 14, 2020
    Inventors: Jean Jianqun Zhao, Toshiyuki Iwata, Zhicai Zhou, Robert Wayne Glenn, JR., Xiaoru Jenny Wang
  • Publication number: 20200146956
    Abstract: This invention relates to oral care compositions comprising a basic amino acid in free or salt from (e.g., free form arginine); zinc oxide and zinc citrate; and a fluoride source comprising stannous fluoride.
    Type: Application
    Filed: January 8, 2020
    Publication date: May 14, 2020
    Applicant: Colgate-Palmolive Company
    Inventors: Paul THOMSON, Nihal DOGU, Michael PRENCIPE, Amy RUSSO, Hans STETTLER, Andre Michelle MORGAN
  • Publication number: 20200146957
    Abstract: Oral care compositions comprising citrulline and stannous ion source with a specific pH range are provided for promoting Gum Health of a user.
    Type: Application
    Filed: January 15, 2020
    Publication date: May 14, 2020
    Inventors: Ross STRAND, Yunming SHI, Yang SU
  • Publication number: 20200146958
    Abstract: Oral care compositions comprising a neutral amino acid and stannous ion source are provided for promoting Gum Health of a user.
    Type: Application
    Filed: January 15, 2020
    Publication date: May 14, 2020
    Inventors: Ross STRAND, Yunming SHI
  • Publication number: 20200146959
    Abstract: Oral care compositions comprising an amino acid and stannous ion source, especially in the absence of zinc ion source, are provided for promoting Gum Health of a user.
    Type: Application
    Filed: January 15, 2020
    Publication date: May 14, 2020
    Inventors: Ross STRAND, Yunming SHI
  • Publication number: 20200146960
    Abstract: The present application relates to antiperspirant compositions comprising perfumes and sulfur-based perfume raw materials, and methods for making and using the antiperspirant compositions.
    Type: Application
    Filed: January 21, 2020
    Publication date: May 14, 2020
    Inventors: Jonathan Robert CETTI, Zerlina Guzdar DUBOIS, Virginia Tzung-Hwei HUTCHINS, Michael Wayne KINSEY
  • Publication number: 20200146961
    Abstract: The present invention relates to a substantially anhydrous shine enhancing spray composition for keratin fibers, especially for human hair, comprising, in a cosmetically acceptable medium, one or more hair setting film forming polymers and a pyrrolidone carboxylic acid ester.
    Type: Application
    Filed: October 11, 2019
    Publication date: May 14, 2020
    Applicant: KAO GERMANY GMBH
    Inventors: Yuqi UELLNER, Sabine Schmid, Christine Cajan
  • Publication number: 20200146962
    Abstract: Use of a naturally glycosylated polyphenol, not containing nitrogen, as protective agent against the effects of ultraviolet irradiation on photo-degradable substances of structures.
    Type: Application
    Filed: May 18, 2017
    Publication date: May 14, 2020
    Inventors: Wolfgang MAYER, Liudmila KORKINA
  • Publication number: 20200146963
    Abstract: The present invention provides a novel topical moisturizing preparation containing as an active ingredient at least one selected from pentosan polysulfate; pharmaceutically acceptable salts of pentosan polysulfate; and pharmaceutically acceptable solvates thereof. The topical moisturizing preparation of the present invention, which contains a substance free of animal-derived components as an active ingredient, can be produced as a topical moisturizing preparation free of animal-derived components, as needed.
    Type: Application
    Filed: May 30, 2018
    Publication date: May 14, 2020
    Applicant: OJI HOLDINGS CORPORATION
    Inventors: Kotaro ISHIKAWA, Takuro KASHIWAMURA, Takuya KATO, Toru KOGA, Suguru ISHIKAWA
  • Publication number: 20200146964
    Abstract: Formulation to treat the scalp and/or hair are provided herein. For example, formulations for reducing inflammation of hair follicles are provided, which, in turn, in some aspects, can help facilitate hair strengthening, smoothness and/or shine.
    Type: Application
    Filed: January 10, 2020
    Publication date: May 14, 2020
    Inventors: Iris RUBIN, Gregory MAGED, John GARRUTO, Bethany McCARVER
  • Publication number: 20200146965
    Abstract: Personal care products are provided. An exemplary personal care product includes a composition that is applied to the body or clothing, or an article applied against the body; a plurality of particles associated with the composition or a component of the article, the plurality of particles, at least some of the plurality of particles comprising a cyclodextrin complexing material and a first fragrance material, wherein the percent of the first fragrance material that is complexed with the cyclodextrin is greater than about 90%, so that the perceptibility of the first fragrance is minimized prior to its release; and a second fragrance material that is not complexed with the cyclodextrin and that is different from the first fragrance material, wherein the composition or article does not contain an antiperspirant active.
    Type: Application
    Filed: November 8, 2018
    Publication date: May 14, 2020
    Inventors: Timothy Alan Scavone, Michael Jude Leblanc, Lowell Alan Sanker, Andrian Gregory Switzer
  • Publication number: 20200146966
    Abstract: Improved undyed substrate formulations described herein have enhanced dye fixation and colorfastness due to opposite electrostatic charges between the base material and the dye. The substrate or base material is formulated to possess an electrostatic charge through the addition of one or more polar or otherwise charged ingredients. A printer device may be used to apply dye to the substrate formulations in a selected image, pattern, or color to produce a customized cosmetic having enhanced dye retention.
    Type: Application
    Filed: November 14, 2019
    Publication date: May 14, 2020
    Applicant: Gracemink, Inc.
    Inventor: Minkyung Grace Choi
  • Publication number: 20200146967
    Abstract: Methods of enhancing deposition of a high viscosity benefit agent can include manufacturing a personal care composition comprising the high viscosity benefit agent and a low viscosity benefit agent by adding the high viscosity benefit agent and the low viscosity benefit agent separately to a cleansing phase.
    Type: Application
    Filed: January 13, 2020
    Publication date: May 14, 2020
    Inventors: Karl Shiqing WEI, Scott William SYFERT, Shannon Dale WAGERS, Brent William MASON
  • Publication number: 20200146968
    Abstract: The present invention relates to a cosmetic composition comprising, in a physiologically acceptable medium, at least water, at least alkylcellulose, at least a first nonvolatile oil chosen from silicone oils and/or fluoro oils, and at least a second hydrocarbon-based nonvolatile oil chosen from C10-C26 alcohols, preferably monoalcohols; monoesters, dieters or triesters of a C2-C8 monocarboxylic or polycarboxylic acid and of a C2-C8 alcohol, which are optionally hydroxylated; and polyesters of a C2-C8 polyol and of one or more C2-C8 carboxylic acids.
    Type: Application
    Filed: January 16, 2020
    Publication date: May 14, 2020
    Applicant: LOREAL
    Inventors: Roberto CAVAZUTTI, Nathalie GEFFROY-HYLAND, Emille NGUYEN-HENIN
  • Publication number: 20200146969
    Abstract: Disclosed is a hydrophilic cosmetic composition comprising a surfactant and Dead Sea salts in the form of solid granules. The surfactant may include a mixture of an anionic surfactant and an amphoteric surfactant or a mixture of a non-ionic surfactant and an amphoteric surfactant. Disclosed is a hydrophilic cosmetic composition comprising a surfactant and Dead Sea salts in the form of solid granules. The surfactant may include a mixture of an anionic surfactant and an amphoteric surfactant or a mixture of a non-ionic surfactant and an amphoteric surfactant.
    Type: Application
    Filed: July 25, 2018
    Publication date: May 14, 2020
    Applicant: Seacret Spa Ltd.
    Inventors: Isabelle AFRIAT STALOFF, Clara KOREN
  • Publication number: 20200146970
    Abstract: A method of treating skin by reducing tumor necrosis factor alpha (TNF-?) activity or matrix metalloproteinase enzyme (MMP-1) activity in a person's skin is disclosed. The method can include topically applying a composition that includes an effective amount of an extract of Brachychiton acerifolius to the person's skin to reduce TNF-? activity or MMP-1 activity in the skin.
    Type: Application
    Filed: January 9, 2020
    Publication date: May 14, 2020
    Inventors: Tiffany CARLE, David GAN, Michelle HINES
  • Publication number: 20200146971
    Abstract: The present invention provides a process for obtaining an extract from White Truffle (Tuber magnatum) for skin cosmetic use, the white truffle extract obtainable by the process and a cosmetic composition comprising the said extract. The invention provides a method for reducing the signs of aging and lightening the skin.
    Type: Application
    Filed: April 10, 2018
    Publication date: May 14, 2020
    Applicant: ISP Investments LLC
    Inventors: Corinne COQUET, Rachel CHABERT
  • Publication number: 20200146972
    Abstract: Compositions comprising from about 0.5 to about 40 percent by weight of an extract of black cohosh, from about 0.5 to about 20 percent by weight of nonionic surfactant, and from about to 40 about 99 percent by weight of hydroxylated solvent are effective in enhancing eyebrow appearance.
    Type: Application
    Filed: November 14, 2018
    Publication date: May 14, 2020
    Inventors: Renata Marie Vestevich, Arun Nandagiri
  • Publication number: 20200146973
    Abstract: A pharmaceutical composition for oral delivery of hydrophobic small molecule drug and hydrophilic small molecule drug concurrently is provided. The pharmaceutical composition includes an enteric layer and a drug layer, in which the drug layer is encapsulated in the enteric layer. The drug layer includes a therapeutically effective amount of a hydrophobic small molecule drug, a therapeutically effective amount of a hydrophilic small molecule drug, a lipophilic solvent, an acidic compound and an effervescent ingredient.
    Type: Application
    Filed: December 6, 2019
    Publication date: May 14, 2020
    Inventors: Hsing-Wen SUNG, Po-Yen LIN, Kuan-Hung CHEN
  • Publication number: 20200146974
    Abstract: The present disclosure relates to a composition for injection, which comprises a pharmaceutically acceptable salt of a compound represented by Formula 1 and one or more selected from mannitol, trehalose, lactose and glucose as a stabilizing agent, having improved stability.
    Type: Application
    Filed: July 6, 2018
    Publication date: May 14, 2020
    Applicant: CJ HEALTHCARE CORPORATION
    Inventors: Hyo Jin KIM, Sung Jun KIM, Min Kyoung LEE, Sung Ah LEE, Mi Young YOON
  • Publication number: 20200146975
    Abstract: In one aspect, the present disclosure provides for novel compositions of matter comprising multi domain peptide (MDP) hydrogels and cyclic dinucleotides (CDNs). Also disclosed are method of using such compositions in the treatment of cancer, including in particular the treatment of head and neck cancers, such as those resistant to CDN therapy.
    Type: Application
    Filed: June 15, 2018
    Publication date: May 14, 2020
    Applicants: WILLIAM MARSH RICE UNIVERSITY, THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Simon YOUNG, David LEACH, Jeffrey D. HARTGERINK
  • Publication number: 20200146976
    Abstract: The invention provides compositions and methods for the treatment of presbyopia. The compositions preferably comprise aceclidine. The compositions optionally contain a surfactant and a viscosity agent.
    Type: Application
    Filed: January 20, 2020
    Publication date: May 14, 2020
    Inventor: Gerald Horn
  • Publication number: 20200146977
    Abstract: Provided is a pharmaceutical composition for oral administration in which the solubility and/or dissolution properties of enzalutamide are improved and supersaturation is maintained. Also provided is a pharmaceutical composition for oral administration in which the oral absorbability of enzalutamide is improved. The pharmaceutical composition for oral administration comprises enzalutamide and polyvinyl alcohol.
    Type: Application
    Filed: April 27, 2018
    Publication date: May 14, 2020
    Inventors: Yoshiaki Umemoto, Takatsune Yoshida, Sachie Namiki, Akira Takagi, Ryo Kojima, Toshiro Sakai, Shinsuke Oba, Hajime Aoki
  • Publication number: 20200146978
    Abstract: There is provided a method for preparing an orally disintegrating tablet (ODT) composition comprising microparticles of one or more taste-masked active pharmaceutical ingredient(s), rapidly-dispersing microgranules, and other optional, pharmaceutically acceptable excipients wherein the ODT disintegrates on contact with saliva in the buccal cavity in about 60 seconds forming a smooth, easy-to-swallow suspension. Furthermore, the microparticles (crystals, granules, beads or pellets containing the active) applied with a taste-masking membrane comprising a combination of water-insoluble and gastrosoluble polymers release not less than about 60% of the dose is in the stomach in about 30 minutes, thus maximizing the probability of achieving bioequivalence to the reference IR product having rapid onset of action (short Tmax). A process for preparing such compositions for oral administration using conventional fluid-bed equipment and rotary tablet press is also disclosed.
    Type: Application
    Filed: January 9, 2020
    Publication date: May 14, 2020
    Inventor: Gopi M. VENKATESH
  • Publication number: 20200146979
    Abstract: The invention provides gastric residence systems, or components of gastric residence system such as segments or elongate members of gastric residence systems, with release rate-modulating films and methods for making and using such systems. The release rate-modulating films provide good control over release of agents (such as therapeutic, diagnostic, or nutritional agents) present in the gastric residence system. The films also permit higher drug loading in the gastric residence systems and components of gastric residence systems while maintaining good control over release of agents. Some embodiments of the films can provide resistance against burst release of agent upon exposure to alcohol.
    Type: Application
    Filed: June 8, 2018
    Publication date: May 14, 2020
    Inventors: Rosemary KANASTY, Nupura BHISE, Stephen ZALE, Bennett CARTER, Jung Hoon YANG, Andrew BELLINGER, Susan LOW, James WRIGHT, David ALTREUTER, Colin GARDNER
  • Publication number: 20200146980
    Abstract: A composition that is self-foaming in an acid medium, and includes: at least one hydrophilic polymer, at least one compound capable of crosslinking the hydrophilic polymer by forming ionic bonds, at least one foaming agent, and at least one foam stabilizer agent; and to the use thereof as a drug, particularly for preventing and/or treating obesity.
    Type: Application
    Filed: June 19, 2018
    Publication date: May 14, 2020
    Applicant: JELLYNOV
    Inventors: Jean-Michel SIMON, Stéphane ROGER
  • Publication number: 20200146981
    Abstract: A method of introducing a physiologically-active agent into the circulatory system of a mammal is disclosed herein. The method utilizes a rapid drug delivery system which prevents deactivation or degradation of the active agent being administered to a patient in need of treatment. In particular, the drug delivery system is designed for pulmonary drug delivery such as by inhalation, for delivery of the active agents such as proteins and peptides to the pulmonary circulation in a therapeutically effective manner avoiding degradation of the active agents in peripheral and vascular tissue before reaching the target site.
    Type: Application
    Filed: January 13, 2020
    Publication date: May 14, 2020
    Inventors: Peter Richardson, Robert A. Baughman, Andrea Leone-Bay, Donald Costello
  • Publication number: 20200146982
    Abstract: The present disclosure provides for brewing apparatus, such as a disposable brewing pod, filter, beverage screen, or tea bag, treated with an oil-based solution comprising a lipid component; an emulsifier; and a pharmaceutical, holistic, or medical component. Brewing apparatus may be sprayed with a spray gun, such as a high volume low pressure spray gun, a precision bottle-top dispenser, or an automatic apparatus configured to apply an oil-based solution to the brewing apparatus. The brewing apparatus may be filled with a product to be brewed and packaged for individual use. The present disclosure additionally provides for a brewed drinkable product produced using brewing apparatus treated with an oil-based solution comprising a lipid component; an emulsifier; and a pharmaceutical, holistic, or medical component. The end product may be a hot or cold product.
    Type: Application
    Filed: January 21, 2020
    Publication date: May 14, 2020
    Applicant: GGCC, Inc
    Inventors: Kristy A. Fischer, Christopher M. Haase
  • Publication number: 20200146983
    Abstract: A method for delivery of an active antibiotic agent to a localized, infected site involves steps of creating an ointment by combining an active antibiotic agent with a tissue penetrating solvent suitable for solubilizing a non-liquid active pharmaceutical ingredient, a tissue penetrating diluent, and a stabilizer for maintaining the ointment, which also functions to as a stabilizer for maintaining chemical stability and resistance to degradation, adjusting viscosity of the ointment by adjustment of amount of the solvent, determining location and extent of the infected site, and applying a predetermined volume of the ointment over skin at the infected region.
    Type: Application
    Filed: July 25, 2019
    Publication date: May 14, 2020
    Inventors: Christopher Ayo Otiko, David R. Pozek
  • Publication number: 20200146984
    Abstract: Disclosed is a composition comprising a cannabinoid and at least one of an essential oil, an herbal extract, a sleep aid-compound, or any combination thereof. Further disclosed is a method for treating a condition modulated by the activation of cannabinoid receptors CB1, CB2, or both, wherein the method comprising administering the composition of the invention. Further disclosed is a method for preparing a cannabis gel.
    Type: Application
    Filed: June 27, 2018
    Publication date: May 14, 2020
    Applicant: PANAXIA PHARMACEUTICAL INDUSTRIES LTD.
    Inventors: Dadi David SEGAL, Or SEGAL, Eran GOLDBERG
  • Publication number: 20200146985
    Abstract: A gel composition comprising silicone crosspolymer and silicone oil wherein the composition when applied to the skin adheres to the skin with a work of adhesion of more than about 0.500 Newton·sec when measured by TA.XT plus text analyzer using a mucoadhesive rig and forms a film with a coefficient of friction of less than 0.400 when measured by Automatic surface tester (method ASTM D 1894).
    Type: Application
    Filed: July 17, 2018
    Publication date: May 14, 2020
    Inventor: Maharukh RUSTOMJEE
  • Publication number: 20200146986
    Abstract: The invention provides an aqueous pharmaceutical solution for use in the treatment of diseases of the central nervous system (CNS), the solution comprising at least 5 mg/ml dissolved levodopa, and having a pH in the range of 3.0 to 8.5. Said solution is provided by mixing a) an aqueous stock solution comprising levodopa, said stock solution having a pH of less than 2.8 at 25° C. and b) an aqueous buffering solution, for increasing the pH of said stock solution, said buffering solution having a pH of at least 4.0 at 25° C. The aqueous pharmaceutical solution is administered to a subject suffering from a disease of the central nervous system (CNS) shortly after mixing of the aqueous stock solution and the aqueous buffering solution. Furthermore, the invention provides a kit for administration of aqueous pharmaceutical solutions to subjects suffering from diseases of the central nervous system (CNS).
    Type: Application
    Filed: June 5, 2018
    Publication date: May 14, 2020
    Inventors: Elias ERIKSSON, Nil DIZDAR SEGRELL, Mats EHRNEBO, Leif BRING
  • Publication number: 20200146987
    Abstract: A method to quickly adjust the size of micelles and then return the micelles to a persistent state is provided. Specifically, the present invention is directed to a method for block copolymer micelle growth under high-?N solution conditions where ultrasonic cavitation facilitates rapid solution-gas interface production that accelerates micelle growth by an order of magnitude over other methods such as vortexing. The persistent micelles formed by the method of the present invention can then be used for controlled delivery of dispersions in organic electronic coatings, paint, or drug delivery applications and can also be used to control the pore size of films that include an oxide, a nitride, a carbide, a metal, or a carbon material.
    Type: Application
    Filed: September 6, 2017
    Publication date: May 14, 2020
    Inventors: Morgan STEFIK, Hasala N. LOKUPITIYA
  • Publication number: 20200146988
    Abstract: The present invention relates to nano-liposome carrier compositions that encapsulate a hybrid of a Cas9 protein and a guide RNA and methods of making and using the same. The nano-liposome carrier compositions have an excellent effect of suppressing expression of target DNA, and thus pharmaceutical compositions including the nano-liposome carrier compositions can be used for treating diseases such as diabetes.
    Type: Application
    Filed: June 12, 2019
    Publication date: May 14, 2020
    Inventor: Kyeong-Nam Yu
  • Publication number: 20200146989
    Abstract: The present invention relates to co-amorphous formulation of a substance and a dipeptide. The present invention also relates to pharmaceutical, cosmetic or veterinary compositions comprising the co-amorphous formulation as well as to methods for preparing and using the co-amorphous formulation.
    Type: Application
    Filed: December 22, 2017
    Publication date: May 14, 2020
    Inventors: Korbinian Löbmann, Thomas Rades, Holger Grohganz, Wenqi Wu, Jan Schnitzkewitz, Astrid Knuhtsen, Daniel Sejer Pedersen
  • Publication number: 20200146990
    Abstract: The present invention relates to a binder composition of different natural/organic binders to ensure efficient tablet manufacturing and batch to batch consistency with avoiding the risk of having capping or lamination problems during the manufacturing process. The composition comprises a blend of components selected from a blend of components selected from: a. of about 5% to about 65% by weight guar gum, xanthan gum or a combination thereof; b. of about 5% to about 65% by weight gum arabic; of about 5% to about 65% by weight pullulan, honey powder, agave powder, or isolated pea protein or any combination of the foregoing; and d. about 1% to about 15% by weight natural plant fibers, all weight percentages being based on the dry weight of the binder composition.
    Type: Application
    Filed: March 14, 2018
    Publication date: May 14, 2020
    Applicant: Biogrund GmbH
    Inventors: Felix SPECHT, Mahmud YUNIS
  • Publication number: 20200146991
    Abstract: A single dosage form that delivers a tripulse (i.e., three pulses) release profile is provided. The dosage form includes at least three dosage units inside the final dosage form. By providing a single dosage form with multiple dosage units, the dosing frequency is decreased since precise blood levels of the active over a prolonged time period are controlled and achieved.
    Type: Application
    Filed: November 12, 2019
    Publication date: May 14, 2020
    Applicant: Cingulate Therapeutics LLC
    Inventors: Matthew Brams, Raul Silva, Arthur Straughn
  • Publication number: 20200146992
    Abstract: The present invention relates to oral controlled-release formulations of 5-(pyridinyl)-2(1H)-pyridinone compounds and their use in the treatment of a subject with heart failure, a stage, class or manifestation of heart failure, or at risk of developing or exhibiting symptoms of heart failure. The formulations of the invention release the compounds in the range of between 0.1 ?g/kg body weight/minute and 20 ?g/kg body weight/minute.
    Type: Application
    Filed: January 17, 2020
    Publication date: May 14, 2020
    Inventors: David Martin Kaye, Guy Krippner, Geetha Thanga Mariappan
  • Publication number: 20200146993
    Abstract: The present disclosure is directed to compositions and methods for the production of a fast dissolving tablets to be used for the delivery of an agent. An agent can be an active pharmaceutical agent or a non-pharmacological agent, which is needed to be delivered by means of a fast dissolving delivery system. The invention solves many industry challenges within the field of fast dissolve technologies, specifically coupling of fast dissolve properties with required physical attributes of strength/robustness required for commercial production and distribution.
    Type: Application
    Filed: November 20, 2019
    Publication date: May 14, 2020
    Inventor: Owen Murray
  • Publication number: 20200146994
    Abstract: The present disclosure utilises 3D printing technology, particularly fused filament fabrication, FFF, 3D printing, in conjunction with solid and/or liquid dispensers to produce solid dosage forms, such as pharmaceutical capsules. Such solid dosage forms have a shell, which is 3D printed, and a core, which is dispensed.
    Type: Application
    Filed: July 25, 2017
    Publication date: May 14, 2020
    Inventors: Mohamed ALBED ALHNAN, Tochukwu Chijioke OKWUOSA
  • Publication number: 20200146995
    Abstract: A nanoparticle capable of crossing tissue has an iron oxide core, a first therapeutic agent, and a polymeric coating. The nanoparticles can be sterilized or part of a lyophilized formation.
    Type: Application
    Filed: June 30, 2018
    Publication date: May 14, 2020
    Inventors: Benjamin Shapiro, Mohammed Shukoor