Patents Issued in June 2, 2020
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Patent number: 10668266Abstract: Ports, such as the ports of ported catheters or of female luer fittings, can be configured to include an antimicrobial septum for disinfecting devices that are attached to the ports. The antimicrobial septum can be positioned within the lumen of the port. The lumen can include an annular recess for securing the antimicrobial septum in place during use. The antimicrobial septum can include an antimicrobial lubricant which transfers onto a device, such as a male luer, as the device passes through the septum thereby killing any microbes that may be present on the surfaces of the device. The antimicrobial septum can be configured in various shapes including a continuous disk shape, a ring shape, or an elongated ring or tube shape. When configured as a ring or tube shape, the inner surfaces of the antimicrobial septum may contain slits or grooves.Type: GrantFiled: April 23, 2014Date of Patent: June 2, 2020Assignee: Becton, Dickinson and CompanyInventors: Janice Lin, Huibin Liu, Bryan Fred Bihlmaier
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Patent number: 10668267Abstract: This disclosure describes example applicators and cap devices which may be used in combination with one or more cleansing, antimicrobial and/or antiseptic agents to reduce or eliminate contaminates on a surface. According to some embodiments, the disclosure describes a first cap which may be stored within a cavity of a second cap to create a dual cap device. According to some embodiments, both caps of the dual cap device may be individually sealed with a protective film. According to some embodiments, either a single cap device or a dual cap device may be attached to a flexible substrate by a surface other than the surface having the cavity opening.Type: GrantFiled: November 11, 2016Date of Patent: June 2, 2020Assignee: Hyprotek, Inc.Inventor: Patrick O. Tennican
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Patent number: 10668268Abstract: A medical connector for use in a fluid pathway. A valve member with sealing rings helps preclude undesired accumulation of fluid within the connector. A branched connector includes a fluid diverter extending away from a port of the branched connector. The fluid diverter is configured to divert fluid flowing through the branched connector and into a medical connector attached thereto, flushing a distal portion of the medical connector.Type: GrantFiled: September 29, 2017Date of Patent: June 2, 2020Assignee: ICU Medical, Inc.Inventors: David Nelson, Thomas F. Fangrow
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Patent number: 10668269Abstract: A connector which couples to an outlet conduit to decrease an outlet conduit passageway pressure differential between outlet conduit opposing first and second ends, whereby the connector includes a mixing chamber having a first inlet port in fluidic communication with a connector first open end and the mixing chamber; an outlet port in fluidic communication with the mixing chamber and a connector second open end; and a second inlet port in fluidic communication with the connector second open end and the mixing chamber. Additionally, a connector including a connector internal surface defining a connector passageway which communicates between connector first and second open ends; and a sensor module operatively coupled to the connector passageway to sense a parameter of a first fluid flowing in a first fluid flow path through the connector passageway.Type: GrantFiled: January 23, 2018Date of Patent: June 2, 2020Assignee: Wilmarc Holdings, LLCInventors: Paul C. Ciccone, William A. Coulson, Marcia Coulson
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Patent number: 10668270Abstract: Implantable leadless cardiac pacing systems and methods for providing substernal pacing using the leadless cardiac pacing systems are described. In one embodiment, an implantable leadless cardiac pacing system includes a housing, a first electrode on the housing, a second electrode on the housing, and a pulse generator within the housing and electrically coupled to the first electrode and the second electrode. The housing is implanted substantially within an anterior mediastinum of a patient and the pulse generator is configured to deliver pacing pulses to a heart of the patient via a therapy vector formed between the first and second electrodes.Type: GrantFiled: April 25, 2014Date of Patent: June 2, 2020Assignee: Medtronic, Inc.Inventors: Amy E. Thompson-Nauman, Melissa G. T. Christie, Paul J. DeGroot, Rick D. McVenes
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Patent number: 10668271Abstract: A surgically implanted lead stabilizer used to stabilize leads is described herein. A lead stabilizer may include a plate that is permanently or semi-permanently surgically installed on a patient's skull under their skin via screws. The plate may hold one or more lead in place. In further embodiments, the plate has two hinged halves that may be affixed fully closed or may include a slotted arm allowing the two hinged halves to be affixed partially open. The plate may include apertures through which electrical leads may pass. Example leads may be guided through one or more surface channels on the top surface of the plate causing the leads to lay flat along the patient's skull.Type: GrantFiled: September 26, 2017Date of Patent: June 2, 2020Inventors: Brian A. Buss, Kris Smith
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Patent number: 10668272Abstract: A cochlear implant of a cochlear implant system is described. The cochlear implant comprises electrodes which are mechanically connected to one another and can be inserted in a row in the form of a spiral into a cochlea in order for auditory nerve receptors to be stimulated, a control circuit that can specifically apply electric pulses to the individual electrodes, and an energy source. The control circuit allows the electrodes to be fed in a pulsed manner with electric signals generated by a processor from the acoustic signals, and auditory nerve receptors adjacent to the electrodes to be stimulated. The electrodes are components of modules, each of which comprises its own decoder-and-control circuit for decoding module addresses and stimulation signals and generating electric pulses for the electrodes. Encoded module addresses and stimulation signals generated from acoustic signals are applied to inputs of the decoder-and-control circuit.Type: GrantFiled: July 27, 2016Date of Patent: June 2, 2020Assignees: MEDIZINISCHE HOCHSCHULE HANNOVER, GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVERInventors: Holger Blume, Wolfgang Ertmer, Thomas Lenarz, Andrej Kral
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Patent number: 10668273Abstract: A device is described that includes a neural interface and a lead body. The lead body and the neural interface are formed from a flexible circuit. The flexible circuit includes an exposed electrode. The lead body includes an elongate planar strand that is coiled about a central axis of the lead body. The elongate planar strand includes a conductive trace extending between the exposed electrode and a distal end of the elongate planar strand.Type: GrantFiled: June 1, 2018Date of Patent: June 2, 2020Assignee: VERILY LIFE SCIENCES LLCInventor: Kedar Shah
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Patent number: 10668274Abstract: The present disclosure provides systems and methods for deploying a paddle neurostimulation lead within a patient. A delivery tool includes a delivery tube including a first linear segment, a second linear segment, and an arcuate segment coupled between the first and second linear segments, the second linear segment defining an elongated opening. The delivery tool further includes a stylet positioned within an interior of the delivery tube, and a handle coupled to the delivery tube and including a stylet actuation mechanism, the stylet actuation mechanism configured to selectively advance and retract the stylet between a deployed position and a retracted position, wherein the stylet extends across the elongated opening in the deployed position to engage an engagement member of the paddle neurostimulation lead.Type: GrantFiled: August 23, 2018Date of Patent: June 2, 2020Assignee: Advanced Neuromodulation Systems, Inc.Inventor: Jeffrey T. Mitchell
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Patent number: 10668275Abstract: A process for manufacturing an electrical lead having one or more electrodes includes providing an elongate member having at least one polymeric region and further having at least one electrical conductor that extends along at least a part of a length of the elongate member and that is contained in a wall of the elongate member. A length of the at least one electrical conductor is accessed at the at least one polymeric region. An electrically conductive adhesive is applied to the length of the at least one electrical conductor that has been accessed.Type: GrantFiled: August 29, 2012Date of Patent: June 2, 2020Assignee: CATHRX LTDInventors: Neil L. Anderson, Norman Booth, Evan K. Chong
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Patent number: 10668276Abstract: The present disclosure involves a method of setting stimulation parameters for neurostimulation. A plurality of stimulation parameters available for bracketing is displayed. The stimulation parameters are selected from the group consisting of: stimulation current amplitude, pulse width, frequency, and contact location. Thereafter, in response to an input from a user, at least a subset of the stimulation parameters is selected for bracketing. A respective initial value is then obtained for each of the stimulation parameters in the selected subset. Thereafter, a bracketing process is used to generate a plurality of bracketed values for each of the stimulation parameters in the selected subset. The bracketed values are generated as a function of the initial value. A plurality of stimulation pulses is then delivered to a patient through a neurostimulator that is automatically programmed with a different combination of the bracketed values for the stimulation parameters for each stimulation pulse.Type: GrantFiled: August 22, 2013Date of Patent: June 2, 2020Assignee: Cirtec Medical Corp.Inventors: Norbert Kaula, Yohannes Iyassu
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Patent number: 10668277Abstract: Detecting dislodgement of a ventricular lead coupled to an implantable medical device comprises sensing a near-field cardiac EGM via a first electrode of the ventricular lead and a far-field cardiac EGM via a second electrode of the ventricular lead, identifying, R-waves in the near-field cardiac EGM and the far-field cardiac EGM. determining a near-field value of one or more R-wave amplitude metrics based on amplitudes of R-waves identified in the near-field cardiac EGM and a far-field value of the one or more R-wave amplitude metrics based on amplitudes of R-waves identified in the far-field cardiac EGM, detecting dislodgement of the ventricular lead based on at least one of the near-field value or the far-field value of the one or more R-wave amplitude metrics; and providing a lead dislodgment alert in response to detecting the dislodgement of the ventricular lead.Type: GrantFiled: December 8, 2017Date of Patent: June 2, 2020Assignee: Medtronic, Inc.Inventors: Bruce D. Gunderson, Charles D. Swerdlow
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Patent number: 10668278Abstract: Catheter devices can include an elongate housing extending along a major axis, the elongate housing comprising a first end an opening. The catheter devices can also include an electrode assembly disposed in the elongate housing and including deformable electrodes with respective electrode distal ends, where the electrode distal ends each consist of respective member portions and respective tip portions. The electrode assembly is slidably movable within the housing along the major axis to allow the electrode distal end portions to transition between a first retracted position and a second extended position. The catheter device is configured such that an average distance between the tip portions in the second position is configured to be greater than an average distance between the tip portions in the first position the tip portions are positioned substantially in a same plane when the electrode assembly is in the second position.Type: GrantFiled: March 24, 2015Date of Patent: June 2, 2020Assignee: Old Dominion University Research FoundationInventors: Richard Heller, Chen Yeong-Jer
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Patent number: 10668279Abstract: The disclosure is directed to a device for electroporating and delivering one or more antigens and a method of electroporating and delivering one or more antigens to cells of epidermal tissues using the device. The device comprises a housing, a plurality of electrode arrays projecting from the housing, each electrode array including at least one electrode, a pulse generator electrically coupled to the electrodes, a programmable microcontroller electrically coupled to the pulse generator, and an electrical power source coupled to the pulse generator and the microcontroller. The electrode arrays define spatially separate sites.Type: GrantFiled: February 1, 2018Date of Patent: June 2, 2020Assignee: Inovio Pharmaceuticals, Inc.Inventors: Kate Broderick, Jay McCoy, Stephen V. Kemmerrer
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Patent number: 10668280Abstract: Methods and systems are provided for triggering electrical stimulation of a spinal cord during execution of a motor event. In one example, a method comprises monitoring motor cortex activity while execution of a desired motor movement is attempted during a first mode where one or more nerve fibers are not stimulated, and during a second mode where the one or more nerve fibers are stimulated. Delivery timing of electrical stimulation may be closed-loop controlled based on current motor cortex activity and the motor cortex activity recorded previously during both the first and second modes.Type: GrantFiled: November 1, 2016Date of Patent: June 2, 2020Assignee: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)Inventors: Tomislav Milekovic, Marco Capogrosso, Gregoire Courtine, Eduardo Martin Moraud, Fabien Wagner, Jerome Gandar
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Patent number: 10668281Abstract: In order to make advanced gait training easy and effective, an electrical spinal cord stimulator for gait training used in gait training for those who have difficulty in walking due to hemiplegia includes: first and second electrodes attached to a rehabilitant; a detector which detects a gait-related physical movement of the rehabilitant; and an electrical sensory nerve stimulation generator which generates, according to a detection result of the detector, electrical stimulation to be applied through the first and second electrodes to a nerve root of a sensory nerve which communicates with a spinal cord.Type: GrantFiled: March 14, 2016Date of Patent: June 2, 2020Assignees: Tokai University Educational System, Keio UniversityInventors: Toshiyuki Fujiwara, Yoshihisa Masakado, Junichi Ushiba
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Patent number: 10668282Abstract: A system is provided for a Transcutaneous Electrical Nerve or Electrical Muscle Stimulation. The system generally includes at least two electrodes carried on a single substrate adapted to be disposed in electrical contact with a body surface, and an electrical stimulation unit configured to deliver electrical pulses to muscle groups or nerve endings adjacent a body surface that is in electrical contact with the at least two electrodes. The electrical stimulation unit includes an on-board controller configured for controlling the stimulation unit to deliver electrical pulses for pain relief and/or muscle relaxation.Type: GrantFiled: August 15, 2016Date of Patent: June 2, 2020Inventor: Eric Ye Chen
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Patent number: 10668283Abstract: A method of configuring a local brain stimulation tool is disclosed. The method comprises: obtaining a reference brain network activity (BNA) pattern, and a BNA pattern describing a neurophysiological state of the subject, each of the BNA patterns having a plurality of nodes and each node representing a brain location and at least one brain wave frequency. The method further comprises comparing the BNA patterns; and configuring the local brain stimulation tool to apply local brain stimulation at a frequency selected based on the comparison.Type: GrantFiled: September 24, 2015Date of Patent: June 2, 2020Assignee: Elminda Ltd.Inventors: Amir B. Geva, Ziv Peremen, Yaki Stern, Amit Reches
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Patent number: 10668284Abstract: A stapedius reflex threshold determination system is communicatively coupled with a loudspeaker and a cochlear implant implanted within a patient. The system identifies a baseline evoked response level associated with a baseline acoustic stimulation level too low to trigger a stapedius reflex within the patient. The system directs an electro-acoustic stimulation event to be applied to the patient, including electrical stimulation applied by the cochlear implant at a particular electrical stimulation level and acoustic stimulation applied by the loudspeaker at the baseline acoustic stimulation level. The system determines an evoked response level associated with the applied acoustic stimulation and detects that the stapedius reflex is triggered by determining that the evoked response level is at least a predetermined threshold amount lower than the baseline evoked response level.Type: GrantFiled: January 31, 2018Date of Patent: June 2, 2020Assignee: Advanced Bionics AGInventors: Kanthaiah Koka, Leonid M. Litvak
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Patent number: 10668285Abstract: It has been discovered that pain felt in a given region of the body can be treated, not by motor point stimulation of muscle in the local region where pain is felt, but by stimulating muscle spaced from a ânerve of passageâ in a region that is superior (i.e., cranial or upstream toward the spinal column) to the region where pain is felt. Spinal nerves such as the intercostal nerves or nerves passing through a nerve plexus, which comprise trunks that divide by divisions and/or cords into branches, comprise ânerves of passage.Type: GrantFiled: November 11, 2011Date of Patent: June 2, 2020Assignee: SPR THERAPEUTICS, INC.Inventor: Joseph W. Boggs, II
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Patent number: 10668286Abstract: Methods and apparatus are disclosed relating to the stimulating of tissue including nerve tissue based on combinations of capacitors and resistors. Application and removal of voltage to an electrical circuit is taught as part of a method of creating voltage waveforms for nerve and other tissue with such waveforms creating neural signals. The electrical circuits taught may, include a first electrical node grounded through a first resistor; a second electrical node grounded through a second resistor; a first capacitor connected to both the first electrical node and the second electrical node; a second capacitor separating the second electrical node from a biological grounding point and direct current sources connected to the two nodes.Type: GrantFiled: November 8, 2016Date of Patent: June 2, 2020Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical CollegeInventors: Jose A. Parodi Amaya, Edward F Austin, Jin-Woo Choi
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Patent number: 10668287Abstract: In various method embodiments for operating an implantable neural stimulator to deliver a neural stimulation therapy to an autonomic neural target, the method comprises using the implantable neural stimulator to deliver the neural stimulation therapy to the autonomic neural target, and evaluating an evoked response to the neural stimulation bursts. The neural stimulation therapy includes a plurality of neural stimulation bursts where each neural stimulation burst includes a plurality of neural stimulation pulses and successive neural stimulation bursts are separated by a time without neural stimulation pulses. Evaluating the evoked response includes sensing the evoked response to the neural stimulation bursts where sensing the evoked response includes sensing at least one physiological parameter affected by the neural stimulation bursts, comparing the sensed evoked response against a baseline, and determining if the evoked response substantially returns to the baseline between neural stimulation bursts.Type: GrantFiled: July 26, 2017Date of Patent: June 2, 2020Assignee: Cardiac Pacemakers, Inc.Inventors: Andrew P. Kramer, Jason J. Hamann
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Patent number: 10668288Abstract: A method and system are provided to deliver nested stimulation to brain tissue of interest. The method and system set first parameters that define a carrier waveform. The method and system set second parameters that define a high frequency waveform, wherein at least one of the carrier waveform and high frequency waveform are defined to correspond to physiologic neural oscillations associated with the brain tissue of interest. The method and system operates a pulse generator to generate a nested stimulation waveform that combines the carrier waveform and high frequency waveform. The nested stimulation waveform has a plurality of pulse bursts. The method and system deliver the nested stimulation waveform through one or more electrodes to the brain tissue of interest.Type: GrantFiled: September 17, 2018Date of Patent: June 2, 2020Inventor: Dirk De Ridder
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Patent number: 10668289Abstract: A method and system are provided for controlling an adaptive pacing therapy using an implantable medical device (IMD). The method provides electrodes that are configured to be located proximate to an atrial (A) site, left ventricular (LV) site and right ventricular (RV) site of the heart. The method utilizes one or more processors to perform obtaining an intra-atrial conduction interval (IACI-LVPROX) between an atrial event and intrinsic conduction at an LV site that is proximal to a sinoatrial (SA) node and obtaining timing of a first heart sound S1. The processors determine whether the S1 occurs after the IACI-LVPROX, and calculates an S1-conduction lag ?S1_C between the IACI-LVPROX and the first heart sound S1. The processors set an atrial-ventricular pacing (AV) delay based on the IACI-LVPROX and the ?S1_C. The processors deliver a pacing therapy based on the AV delay.Type: GrantFiled: July 12, 2018Date of Patent: June 2, 2020Assignee: Pacesetter, Inc.Inventor: Xiaoyi Min
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Patent number: 10668290Abstract: A method and system for delivering cardiac pacing therapy that includes sensing electrical activity of tissue of a patient from a plurality of external electrodes during delivery of a non-ambulatory pacing therapy from a pacing device and determining an optimal electromechanical (EM) response time from an optimal electrical activation determined from electrical heterogeneity information obtained during non-ambulatory pacing therapy. During delivery of subsequent ambulatory pacing, the pacing sensing an EM signal from an EM sensor of the pacing device, determines a current EM response time in response to the sensed EM signal, and adjusting a pacing parameter setting of the ambulatory pacing therapy in response to comparing the current EM response time to the optimal EM response time.Type: GrantFiled: March 1, 2018Date of Patent: June 2, 2020Assignee: Medtronic, Inc.Inventor: Subham Ghosh
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Patent number: 10668291Abstract: In some examples, a system may be used for delivering cardiac therapy or cardiac sensing. The system may include an in implantable medical device including a housing configured to be implanted on or within a heart of a patient, a fixation element configured to attach the housing to the heart; and a sensor configured to produce a signal that indicates motion of the implantable medical device. Processing circuitry may be configured to identify one or more impingements between the housing and another structure, such as a tissue of the heart, based on the signal from the sensor and provide an indication of the one or more impingements to a user.Type: GrantFiled: May 2, 2018Date of Patent: June 2, 2020Assignee: Medtronic, Inc.Inventors: Berthold Stegemann, Richard Cornelussen, Robert W. Stadler
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Patent number: 10668292Abstract: Embodiments describe herein generally pertain to implantable medical device (IMDs), and methods for use therewith, that can be used to automatically switch an IMD from its normal operational mode to an MRI safe mode, and vice versa, within increased specificity. In certain embodiments, a controller of the IMD uses a magnetic field sensor to determine whether a first magnetic field condition is detected, and uses an accelerometer to determine whether a positional condition is detected. In response to the first magnetic field condition being detected, and the positional condition being detected, the controller can use the magnetic field sensor to determine whether a second magnetic field condition is detected, which differs from the first magnetic field condition. The controller can then cause the IMD to enter the MRI safe mode based at least in part on the first and second magnetic field conditions and the positional condition being detected.Type: GrantFiled: March 22, 2018Date of Patent: June 2, 2020Assignee: Pacesetter, Inc.Inventors: Xing Pei, Brad Lindevig, Stuart Rosenberg, Nima Badie
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Patent number: 10668293Abstract: A method and external control device for performing a medical procedure on a patient in which at least one stimulation lead is implanted. An electrical signal is conveyed from the stimulation lead into tissue of the patient. An electrical parameter indicative of tissue impedance is measured in response to the conveyance of the electrical signal. One of a plurality of different anatomical regions in which the stimulation lead is implanted is selected and/or a depth in which the stimulation is implanted is determined based on the measured electrical parameter. A stimulation parameter is defined based on the selected one anatomical region and/or implantation depth. Electrical stimulation energy from the stimulation lead is conveyed into the one determined anatomical region in accordance with the defined stimulation parameter.Type: GrantFiled: January 2, 2018Date of Patent: June 2, 2020Assignee: Boston Scientific Neuromodulation CorporationInventors: Changfang Zhu, Kerry Bradley
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Patent number: 10668294Abstract: Implantable medical devices such as leadless cardiac pacemakers (LCP) may be configured to be delivered to a target location within the heart over a guide wire. In some cases, using a guide wire for delivery facilitates placement of devices in regions not otherwise easily reached. An LCP may include a housing and a wire lumen disposed relative to the housing. The wire lumen may be configured to allow the LCP to slide over a guide wire. In some cases, the guide wire may include a guide wire electrode that may be used to test potential implantation sites.Type: GrantFiled: May 8, 2017Date of Patent: June 2, 2020Assignee: CARDIAC PACEMAKERS, INC.Inventors: Brendan Early Koop, Benjamin J. Haasl, Brandon Christopher Fellows
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Patent number: 10668295Abstract: A stimulation device that stimulates living tissue includes an energy harvesting circuit that receives an output signal from another device and that powers the stimulation device, immediately or otherwise, using the output signal. The stimulation devices also includes a stimulation circuit that generates a stimulation signal to elicit a predetermined response from the living tissue, and at least one lead that delivers the stimulation signal to the living tissue.Type: GrantFiled: April 24, 2015Date of Patent: June 2, 2020Assignee: MR3 MEDICAL, LLCInventors: Alois Langer, Morton M. Mower
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Patent number: 10668296Abstract: A handheld defibrillation device is disclosed, operated by a single battery cell, and configured to deliver a defibrillation pulse to a subject via defibrillation pads. The defibrillator comprises an energy storage unit comprising a plurality of capacitive elements, a plurality of charger units, each charger unit being electrically connected to the battery cell for electrically charging a respective one of the capacitive elements, and a pulse delivery unit configured and arranged to discharge the electrical charges of the capacitive elements through the defibrillation pads. The charging units and the pulse delivery unit, and various other parts of the defibrillator are specially designed to permit compactly packaging the defibrillator inside a handheld pocketsize housing.Type: GrantFiled: November 23, 2016Date of Patent: June 2, 2020Assignee: CARDIFAB LTD.Inventor: Marian Meir
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Patent number: 10668297Abstract: The present invention relates to a magnetic stimulation (MS) and preferably transcranial magnetic stimulation (TMS) coil arrangement designed for use as a placebo treatment. Accordingly, the purpose of the invention is to reduce or remove the effect of the magnetic field generated in use by a magnetic stimulation coil arrangement whilst the appearance presented remains as expected from a MS coil arrangement. The invention comprises a radially wound conductive element having a plurality of turns forming at least one winding. There is further provided at least one conductive magnetic field disrupting element at least partially positioned adjacent to the at least one winding for disrupting a magnetic field generated in operation by the at least one winding. The conductive magnetic field disruptive element accordingly attenuates the generated magnetic field beneath the coil arrangement.Type: GrantFiled: February 23, 2015Date of Patent: June 2, 2020Assignee: The Magstim Company LimitedInventors: Matthew Paul Biginton, Gary Anthony Thomas
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Patent number: 10668298Abstract: In accordance with various aspects of the present teachings, systems and methods for applying treatment energy, e.g., electromagnetic radiation such as laser radiation in the visible and near infrared wavelengths, to body areas having bulges and fat deposits, loose skin, pain, acne and/or wounds. In some aspects, the systems and methods can enable relatively lengthy treatments to be performed by having the practitioner set-up and/or start the treatment, thereafter allowing the treatment to proceed safely and effectively without the continued presence of the practitioner.Type: GrantFiled: December 21, 2018Date of Patent: June 2, 2020Assignee: Cynosure, LLCInventors: James Boll, Rafael Armando Sierra, Elizabeth Kneen Winter, Allan Cameron, Adrian Mark West, Kevin Young, Bo Chen
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Patent number: 10668299Abstract: A brachytherapy system includes a brachytherapy applicator. The brachytherapy applicator includes an applicator tube and a radiation source configured to deliver radiation to a tumor. At least a portion of the applicator tube is configured to conform to at least a portion of a patient's anatomy. At least one ultrasound element or probe is coupled to or embedded with the applicator tube.Type: GrantFiled: April 11, 2016Date of Patent: June 2, 2020Assignee: Nucletron Operations B.V.Inventors: Paulus Cornelis Hendrikus Maria Krechting, Wilhelmus Petrus Martinus Maria Van Erp, Jan F. L. De Becker, Anton J. G. Welberg
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Patent number: 10668300Abstract: Radiation treatment planning and administration can include a Monte Carlo computer simulation tool to simulate photo-generated electrons in tissue. In the simulation, electrons that have left tissue voxels and entered air voxels can be evaluated to identify electrons that are circling along a spiraling trajectory in the air voxels. After at least one full spiraling circumference or other specified distance has been traversed using a detailed electron transport model, a simpler linear ballistic motion model can be instituted. This speeds simulation while accurately accounting for spiraling electrons that re-enter tissue voxels.Type: GrantFiled: December 8, 2017Date of Patent: June 2, 2020Assignee: Elekta, Inc.Inventors: Sami Hissoiny, Michel Moreau
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Patent number: 10668301Abstract: A simple metric, the mean absolute dose deviation (âMADDâ), for characterizing dose-volume histograms (âDVHâ) is disclosed. The MADD facilitates the use and the comparison of DVHs. The MADD is defined as the average of absolute differences between all points of a DVH and a dose point of a specified reference dose range. The MADD is a generalized metric free from distribution assumptions, and it is directly applicable to all types of structures.Type: GrantFiled: July 11, 2018Date of Patent: June 2, 2020Inventors: Vincent Vinh-Hung, Nam P. Nguyen
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Patent number: 10668302Abstract: A system or use with a radiotherapy system includes a scanner for producing images of at least one object within an imaging volume, a radiotherapy apparatus including a source of therapeutic radiation adapted to deliver a beam of radiation into the at least one object, a treatment planning system for controlling the source so as to deliver radiation in accordance with a predetermined plan for treating a patient and with the images of the at least one object, and at least one device within and/or adjacent to the imaging volume. The at least one device comprises at least one first marker which is visible to the scanner and at least one MR second marker which is visible to an MR scanner. The system further comprises a database containing data including the markers associated with the at least one device and at least its geometric and density characteristics.Type: GrantFiled: October 23, 2014Date of Patent: June 2, 2020Assignee: ELEKTA AB (PUBL)Inventors: Christopher Charles Knox, Neil Winchester, David Anthony Roberts, Jill Stief
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Patent number: 10668303Abstract: A radiation treatment device may include a first dosimeter and a second dosimeter. Quantum efficiency of the first dosimeter may be lower than quantum efficiency of the second dosimeter. A method for monitoring beam energy may include receiving a first signal generated by a first dosimeter, receiving a second signal generated by a second dosimeter, receiving a third signal generated by the first dosimeter and receiving a fourth signal generated by the second dosimeter. The first signal and the second signal may be associated with a first radiation beam. The second signal and the fourth signal may be associated with a second radiation beam. The method may also include determining whether there is a difference between the beam energy of the first radiation beam and the second radiation beam based on at least one of the first signal, the second signal, the third signal or the fourth signal.Type: GrantFiled: March 1, 2018Date of Patent: June 2, 2020Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Jonathan Maltz, Walter Aguilar
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Patent number: 10668304Abstract: A deformable radiotherapy phantom can be produced using an additive manufacturing process, based on a medical image of the patient. The deformable phantom can include dosimeters for measuring radiation dose distribution. A smart material can allow deformation in response to an applied stimulus. Among other things, the phantom can be used to validate radiation dose warping, a radiotherapy treatment plan, to determine a maximum acceptable deformation of the patient, to validate a cumulative accuracy of dose warping and deformable image registration, or the like.Type: GrantFiled: April 30, 2018Date of Patent: June 2, 2020Assignee: Elekta, Inc.Inventors: Nicolette Patricia Magro, Xiao Han
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Patent number: 10668305Abstract: Garment systems including a flexible compression garment, at least one sensor, and at least one therapeutic stimulation delivery device operable responsive to sensing feedback from the at least one sensor, effective to provide therapeutic radiation to a body part of a subject. Methods of using such garment systems are also described.Type: GrantFiled: February 16, 2017Date of Patent: June 2, 2020Assignee: ELWHA LLCInventors: Jesse R. Cheatham, III, Roderick A. Hyde, Muriel Y. Ishikawa, Jordin T. Kare, Eric C. Leuthardt, Max N. Mankin, Nathan P. Myhrvold, Tony S. Pan, Robert C. Petroski, Elizabeth A. Sweeney, Clarence T. Tegreene, Nicholas W. Touran, Yaroslav A. Urzhumov, Charles Whitmer, Lowell L. Wood, Jr., Victoria Y. H. Wood
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Patent number: 10668306Abstract: A dentifrice composition having a low water phase comprising effective amounts of polyphosphate and ionic active ingredients.Type: GrantFiled: April 27, 2018Date of Patent: June 2, 2020Assignee: Colgate-Palmolive CompanyInventors: Steven Fisher, Linh Fruge, Michael Prencipe
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Patent number: 10668307Abstract: A safety breathing apparatus has a sensor for measuring the difference in pressure between two point in the gas delivered to a head unit. The sensor is used to measure the difference in the pressure of the gas supplied through the apparatus between the two points in the gas flow, and the pressure difference is then used to calculate the gas flow rate.Type: GrantFiled: June 10, 2016Date of Patent: June 2, 2020Assignee: Scott Health & Safety Ltd.Inventors: Albert F. Zwolinsky, Richard D. Marshall, Christopher G. Hall
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Patent number: 10668308Abstract: A filter mask for filtering air inhaled and exhaled from the mouth and nostrils while providing a secure fit and comfort to the wearer is provided. The filter mask has upper and lower edges which are provided with at least one malleable stiffener for conforming to the shape of the wearer's nose and cheek area and/or the lower jaw and chin area. In some embodiments, the filter masks further comprises a malleable stiffening member configured to conform the filter material to at least a chin portion and a jaw portion of the face. In some embodiments, the malleable stiffener can have a bend portion, which allows the wearer of the mask to know which part, center and side of the mask is to be properly placed on the nose and cheek area. The masks provide excellent filtration and provide a secure and comfortable fit to the wearer.Type: GrantFiled: August 30, 2011Date of Patent: June 2, 2020Assignee: Crosstex International, Inc.Inventors: Richard Allen Orofino, Lou Carbone, Mitchell Victor Steinberg, Andrew Guy Whitehead, Matthew Conlon
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Patent number: 10668309Abstract: A rescue assembly for rapid extrication of a victim from a dangerous environment includes a wearable base member (101, 201) and a rescue strap (103, 104) deployable therefrom. The rescue strap (103, 104) extends outwardly from the base member (101, 201) allowing a rescuer to form a secure connection to a rescue for extrication. Keeper assemblies (208, 209) cooperatively retain the rescue strap (103, 104) within the base member (101, 201) until deployed by the rescuer and a release assembly provides the ability to quickly release the rescue strap from the base member if desired by the rescuer.Type: GrantFiled: April 11, 2016Date of Patent: June 2, 2020Inventors: Sverre Starholm, Rune Nilsen, Tore Buer
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Patent number: 10668310Abstract: The present invention relates to a fire extinguishing system comprising a fire extinguishing medium container (3), a first (5) and second (7) fire extinguishing sub-systems, and a valve assembly (9) fluidly connecting the fire extinguishing medium container (3) to each of the first (5) and second (7) fire extinguishing sub-systems.Type: GrantFiled: June 25, 2015Date of Patent: June 2, 2020Assignee: FOGMAKER INTERNATIONAL ABInventor: Johnny ErnfjÀll
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Patent number: 10668311Abstract: An inert gas-generating fire suppression composition is disclosed, consisting essentially of an oxidizer, comprising ammonium dinitramide and strontium nitrate, a fuel, comprising potassium isocyanurate, a gas-generate fuel, comprising guanidine nitrate and a quantity of carbon black.Type: GrantFiled: March 23, 2018Date of Patent: June 2, 2020Assignee: GOODRICH CORPORATIONInventor: Karl G Reimer
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Patent number: 10668312Abstract: A composition for decomposing pharmaceutically active agents, comprises up to 30 wt. % oxidizer; and up to 30 wt. % immobilizer; wherein the wt. % is based on a total weight of the composition.Type: GrantFiled: June 28, 2019Date of Patent: June 2, 2020Assignee: Okra Medical, Inc.Inventors: Justin Stas, Yizhong Wang, Evan Boyst, Venkata S. Reddy Channu, Emma Leishman
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Patent number: 10668313Abstract: A non-motorized treadmill includes a non-motorized treadmill body and a composite resistance module. The non-motorized treadmill body includes two rollers and a treadmill belt. The treadmill belt is wound around the two rollers. The composite resistance module includes a reluctance module and a fan wheel. The reluctance module includes a wheel body and a resistance member. The wheel body is mounted to one of the rollers. The resistance member is located close to the wheel body. One of the wheel body and the resistance member includes a metal member. The other of the wheel body and the resistance member includes a magnetic member. The fan wheel is connected to one side of the wheel body so that one of the rollers is subjected to magnetic resistance and wind resistance when rotated.Type: GrantFiled: January 15, 2018Date of Patent: June 2, 2020Assignee: GREAT FITNESS INDUSTRIAL CO., LTD.Inventor: Chih-Yung Hsu
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Patent number: 10668314Abstract: An apparatus includes a flywheel, a first pivotable caliper, a first magnet supported by the first caliper opposite the flywheel, a second pivotable caliper and a second magnet supported by the second caliper opposite the flywheel. In one implementation, the apparatus further includes a first cam follower coupled to the first caliper, a second cam follower coupled to the second caliper and at least one cam member including a first cam surface against which the first cam follower moves and a second cam surface against which the second cam follower moves, wherein movement of the at least one cam member pivots the first caliper and the second caliper to move the first magnet and the second magnet relative to the flywheel. In another implementation, the apparatus further includes a strain gauge carried by the first caliper to output signals indicating braking torque.Type: GrantFiled: October 11, 2016Date of Patent: June 2, 2020Assignee: Precor IncorporatedInventors: Brent Christopher Mayer, Kevin C. Andrews
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Patent number: 10668315Abstract: A weight bar support assembly for safely supporting a weight bar on exercise equipment in the event the user cannot return the weight bar to its original position includes an attachment bracket and a weight support member forming a catch arm which is selectively engaged with and moved away from an upright of the exercise equipment. An energy absorbing arrangement is incorporated within either the attachment bracket or the weight support member, and is configured to cushion forces transmitted to the upright upon contact of the weight bar with the weight support member to prevent deformation and/or damage of the exercise equipment.Type: GrantFiled: August 27, 2018Date of Patent: June 2, 2020Assignee: Life Fitness, LLCInventors: Westin W. Nelson, Dennis Whaley, John M. Cassidy, Mathew R. Meyer