Patents Issued in June 18, 2020
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Publication number: 20200188254Abstract: Cosmetic body compositions, particularly in the form of a body moisturizer, are provided. The cosmetic body compositions comprise particles having encapsulated pigments which are capable of evening the body's skin tone by providing a pantyhose effect, improving its overall appearance, hydration, radiance and strengthening its barrier.Type: ApplicationFiled: May 7, 2018Publication date: June 18, 2020Inventors: Cinthia DE SOUZA FERREIRA GARCIA, Lais BRITO SILVA
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Publication number: 20200188255Abstract: The present disclosure relates to hair conditioning spray treatments comprising at least two components selected from: at least one cationic guar derivative, at least one dicarboxylic acid, or a salt or derivative thereof, and at least one cationic surfactant selected from an amidoamine, a permanent cationic amidoamine, and mixtures thereof The present disclosure also relates to methods of conditioning hair using the hair conditioning spray treatments.Type: ApplicationFiled: November 26, 2019Publication date: June 18, 2020Applicant: Henkel AG & Co. KGaAInventors: MARLENE BATTERMANN, SYLVIA KERL
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Publication number: 20200188256Abstract: A silicone-free, transparent hair conditioning composition comprising bis-(isostearoyl/oleoyl isopropyl) dimonium methosulfate, a cosmetic product incorporating the composition, and methods of using the composition.Type: ApplicationFiled: November 19, 2019Publication date: June 18, 2020Applicant: Henkel AG & Co. KGaAInventors: Marlene Battermann, Thomas Schroeder
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Publication number: 20200188257Abstract: The present invention relates to alkoxylated esteramines of Formula (I) and salts thereof. Esteramines according to the present invention may be used in cleaning composition, for example in liquid laundry detergents. They lead to improved cleaning performance of said compositions, for example when used in cold water washing conditions. They surprisingly boost grease cleaning performance of liquid laundry detergents, especially under cold water washing conditions. Whiteness is also improved. The esteramine according to the present invention show improved compatibility in liquid laundry detergent formulations.Type: ApplicationFiled: June 26, 2018Publication date: June 18, 2020Inventors: Bjoern LUDOLPH, Sophia EBERT, Christian BITTNER
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Publication number: 20200188258Abstract: The disclosure relates to compositions for treating keratinous substrates, such as the hair, comprising monoethanolamine and at least one carboxylic acid, as well as systems and methods for treating keratinous substrates with the compositions.Type: ApplicationFiled: December 12, 2019Publication date: June 18, 2020Inventors: Kimberly DREHER, Gérard PROVOT, Dariusz DANIELSKI, Fabien BOULINEAU, Caroline Rahmouna Francoise GOGET, Anthony POTIN, Allison CHIN, Michael DEGEORGE, Mara APPLEBAUM, Mary Abraam SOLIMAN, Ashley Ann FIGATNER, Megan PAUKER, Emmanuel APPIAH-AMPONSAH
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Publication number: 20200188259Abstract: The present disclosure relates to a two-component hair care product which comprises an anhydrous carrier as a first component and an aqueous carrier as a second component separately from each other, wherein the anhydrous carrier contains a) a branched or unbranched alkane, b) a branched or unbranched fatty alcohol, and c) a monovalent branched or monovalent unbranched C2 to C8, preferably C4 to C6 alcohol. The present disclosure relates further to a method for applying the two-component hair care product and use thereof.Type: ApplicationFiled: December 16, 2019Publication date: June 18, 2020Applicant: Henkel AG & Co. KGaAInventors: RENE KROHN, ERIK SCHULZE ZUR WIESCHE
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Publication number: 20200188260Abstract: Disclosed is a method of strengthening hair fibers using a hair composition comprising an amide and/or an alkyl ammonium carboxylate salt. The amide can be a monoamide and/or a bisamide. A method of protecting dyed hair color from fading or wash-out using the hair composition is also included.Type: ApplicationFiled: February 19, 2020Publication date: June 18, 2020Applicant: HERCULES LLCInventors: Gijsbert Kroon, Xiaochun Zhang, Emmanuel Paul Jos Marie Everaert
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Publication number: 20200188261Abstract: The present invention relates generally to compositions and methods of using the same such as, for example, methods of treating the skin of a subject using a composition as described herein. The composition may comprise a diluent, a surfactant, a thickening agent, a humectant, a cooling agent, a chelating agent, optionally a pH adjustment agent, and optionally a preservative. The composition may further comprise L-arginine and/or L-citrulline and/or esters and/or derivatives thereof.Type: ApplicationFiled: June 19, 2018Publication date: June 18, 2020Inventors: Nathan Stasko, Ryan Doxey
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Publication number: 20200188262Abstract: The present invention relates to a method of coloring keratin fibers, especially human hair, which delivers intensive, long lasting, brilliant colors and provides improved grey coverage. Kit therefore is disclosed as well. The method of colouring hair involves treating hair prior to colouring with an alkaline reducing agent.Type: ApplicationFiled: December 21, 2017Publication date: June 18, 2020Applicant: KAO GERMANY GMBHInventors: Bernd NÖCKER, Anne NEU, Fariba GHIASI
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Publication number: 20200188263Abstract: The present disclosure relates to multi-component packaging units (kits-of-parts), ready-to-use agents, and methods for reductive decolourisation of dyed keratinous fibres. In one example, the multi-component packaging unit (kit-of-parts) for reductive decolourisation of dyed keratinous fibres includes, (I) a first container (A) including a cosmetic agent (a) and (II) a second container (B) including a cosmetic agent (b), wherein the first container (A) and the second container (B) are provided separately from one another, the cosmetic agent (a) in the first container (A) includes (a1) one or more reducing agent(s) that is/are solid at room temperature, and (a2) one or more oxidant(s) that is/are solid at room temperature, and wherein the cosmetic agent (b) in the second container (B) comprises (b1) one or more alkalising agent(s).Type: ApplicationFiled: November 19, 2019Publication date: June 18, 2020Applicant: Henkel AG & Co. KGaAInventors: JUERGEN SCHOEPGENS, TORSTEN LECHNER
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Publication number: 20200188264Abstract: The invention relates to non-aqueous dentrfrice compositions comprising a surfactant system. The surfactant system consists of a combination of surfactants i.e. a betaine and a taurate surfactant; or a betaine and an alkyl sulphate surfactant; or a betaine, a taurate and an alkyl sulphate surfactant.Type: ApplicationFiled: December 18, 2019Publication date: June 18, 2020Inventor: John HODGKINSON
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Publication number: 20200188265Abstract: The present invention relates to cosmetic compositions having antioxidant properties and suitable for any type of skin.Type: ApplicationFiled: August 30, 2018Publication date: June 18, 2020Inventors: Jürgen LADEMANN, Leonhard ZASTROW, Martina MEINKE, Stephanie ALBRECHT, Torsten ZUBERBIER, Alexandra LAN
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Publication number: 20200188266Abstract: Disclosed herein are oral care compositions including Zn:usnate complexes having a 1:2 zinc to usnate molar ratio. Methods of making and using the compositions are also provided.Type: ApplicationFiled: February 20, 2020Publication date: June 18, 2020Applicant: Colgate-Palmolive CompanyInventors: Stanislav JARACZ, Long PAN, Karthik SAMBANTHAMOORTHY
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Publication number: 20200188267Abstract: The present disclosure relates to a highly stable basic fibroblast growth factor mutant, and a use thereof. Specifically, the present disclosure provides: a highly stable basic fibroblast growth factor mutant, in which two or more amino acids in an amino acid sequence of SEQ ID NO.: 1 are substituted with serine and one or more amino acids are substituted with cysteine; a DNA base sequence encoding the bFGF mutant; an expression vector including the DNA base sequence; a transformant transformed by the expression vector; a method of producing the bFGF mutant; and a composition including the bFGF mutant as an active ingredient. According to the present disclosure, the bFGF mutant of the present disclosure has excellent stability in an aqueous solution state and excellent thermal stability, and thus it is possible to produce functional cosmetics and skin inflammation medicines which do not lose activity, even during distribution and storage.Type: ApplicationFiled: July 24, 2015Publication date: June 18, 2020Inventors: Hang-Cheol SHIN, Jong-Kwang OH
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Publication number: 20200188268Abstract: A composition is disclosed that includes pure silk fibroin-based protein fragments that are substantially devoid of sericin, wherein the composition has an average weight average molecular weight ranging from about 17 kDa to about 38 kDa, wherein the composition has a polydispersity of between about 1.5 and about 3.0, wherein the composition is substantially homogeneous, wherein the composition between 0 ppm to about 500 ppm of inorganic residuals, and wherein the composition includes between 0 ppm to about 500 ppm of organic residuals.Type: ApplicationFiled: February 19, 2020Publication date: June 18, 2020Inventors: Gregory H. Altman, Rebecca L. Lacouture, Rachel Lee Dow, Rachel M. Lind, Dylan S. Haas
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Publication number: 20200188269Abstract: A composition is disclosed that includes pure silk fibroin-based protein fragments that are substantially devoid of sericin, wherein the composition has an average weight average molecular weight ranging from about 17 kDa to about 38 kDa, wherein the composition has a polydispersity of between about 1.5 and about 3.0, wherein the composition is substantially homogeneous, wherein the composition between 0 ppm to about 500 ppm of inorganic residuals, and wherein the composition includes between 0 ppm to about 500 ppm of organic residuals.Type: ApplicationFiled: February 20, 2020Publication date: June 18, 2020Inventors: Gregory H. Altman, Rebecca L. Horan, Rachel Lee Dow, Rachel M. Lind, Dylan S. Haas
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Publication number: 20200188270Abstract: Disclosed is a polypeptide having a base amino acid sequence and wherein at least two amino acid residue side chains are substituted with functional Michael acceptor groups. Also disclosed are cosmetic compositions including the polypeptide, a method for repairing damaged hair using the polypeptide or composition, and to the use of the polypeptide or composition in such methods.Type: ApplicationFiled: August 24, 2018Publication date: June 18, 2020Inventors: Jaywant PHOPASE, Ranjithkumar RAVICHANDRAN
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Publication number: 20200188271Abstract: A cosmetic composition for treating keratin fibres, contains: (a) fibres (b) ethanol (c) at least one polymer, comprising an acrylate copolymer, and (d) propellant.Type: ApplicationFiled: November 20, 2019Publication date: June 18, 2020Applicant: Henkel AG & Co. KGaAInventors: DIANE METTEN, THORSTEN KNAPPE, TIM BETHGE, RENE SCHEFFLER, ROLF BAYERSDOERFER
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Publication number: 20200188272Abstract: The present invention relates to a cosmetic composition having a cotton candy form. The cosmetic composition in a cotton candy form is prepared by freeze-drying an algin aqueous solution, and thus can be prepared through a simple process, has excellent moldability, and can stably contain, even at room temperature, a protein such as a cytokine, a peptide, and the like, which have particular storage requirements.Type: ApplicationFiled: November 22, 2017Publication date: June 18, 2020Applicant: TEGO SCIENCE INC.Inventors: Saewha JEON, Yun Hee KIM, Jikhyon HAN
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Publication number: 20200188273Abstract: A cosmetic composition for temporary reshaping keratinous fibers, having: a) a cationically modified guar derivative having a weight-average molecular weight in the range of from about 5,000 to about 200,000 and a cationic degree of substitution in the range of from about 0.1 to about 2 and b) at least one polyimide, and their use and a method of using such a composition.Type: ApplicationFiled: December 17, 2019Publication date: June 18, 2020Applicant: Henkel AG & Co. KGaAInventors: JULIA BIBIANE LANGE, CYRIELLE MARTINEZ, DIANE METTEN
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Publication number: 20200188274Abstract: Cosmetic compositions and methods of using the same are provided. An exemplary cosmetic composition for temporarily reshaping keratinous fibers inlcudes: a) a cationically modified guar derivative with a weight average molecular weight in the range of from about 5,000 to about 200,000 and a degree of cationic substitution in the range of from about 0.1 to about 2, and b) at least one associative copolymer which is obtained by reacting a monomer (b1) from the group of acrylic acid, methacrylic acid, C1-C6 alkylacrylic acid ester, and C1-C6 alkylmethacrylic acid ester, with at least one monomer (b2) from the group of C10-30 alkyl acrylates, C10-30 alkyl methacrylates, C10-30 Alkyl PEG-Acrylate, C10-30 Alkyl PEG-Methacrylate or C10-30 Alkyl PEG-Itaconate. The cosmetic composition is used by applying it to keratinous fibers and temporarily fixing the keratinous fibers into a shape.Type: ApplicationFiled: December 17, 2019Publication date: June 18, 2020Applicant: Henkel AG & Co. KGaAInventors: JULIA BIBIANE LANGE, CYRIELLE MARTINEZ, DIANE METTEN
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Publication number: 20200188275Abstract: A cosmetic composition for temporarily reshaping keratinous fibers, containing: a) a cationically modified guar derivative with a weight average molecular weight in the range of from about 5,000 to about 200,000 and a degree of cationic substitution in the range of from about 0.1 to about 2 and b) at least one cationic copolymer which is obtained by reacting vinylpyrrolidone with methacrylamidopropyltrimethylammonium chloride (MAPTAC). A use thereof and a method of using such a composition.Type: ApplicationFiled: December 17, 2019Publication date: June 18, 2020Applicant: Henkel AG & Co. KGaAInventors: JULIA BIBIANE LANGE, CYRIELLE MARTINEZ, DIANE METTEN
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Publication number: 20200188276Abstract: A cosmetic composition for temporarily reshaping keratin fibers, containing: PS a) a cationically modified guar derivative with a weight-average molecular weight in the range of from about 5,000 to about 200,000 and a degree of cationic substitution in the range of from about 0.1 to about 2, and b) at least one cationic, vinylcaprolactam-containing copolymer. A use thereof and a method of utilizing such a composition.Type: ApplicationFiled: December 17, 2019Publication date: June 18, 2020Applicant: Henkel AG & Co. KGaAInventors: JULIA BIBIANE LANGE, CYRIELLE MARTINEZ, DIANE METTEN
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Publication number: 20200188277Abstract: A cosmetic composition for temporarily reshaping keratinous fibres, containing: a) a cationically modified guar derivative with a weight average molecular weight in the range from about 5,000 to about 200,000 and a degree of cationic substitution in the range from about 0.1 to about 2 and b) at least one copolymer which is obtained by reacting at least one ethylenically unsaturated monomer unit (b1) with at least one saccharidic monomer unit (b2), use thereof and method using such a composition.Type: ApplicationFiled: December 17, 2019Publication date: June 18, 2020Applicant: Henkel AG & Co. KGaAInventors: JULIA BIBIANE LANGE, CYRIELLE MARTINEZ, DIANE METTEN
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Publication number: 20200188278Abstract: A cosmetic composition for temporarily reshaping keratinous fibres, containing: a) a cationically modified guar derivative with a weight average molecular weight in the range from about 5,000 to about 200,000 and a degree of cationic substitution in the range from about 0.1 to about 2 and b) at least one copolymer comprising b1) quaternised vinylimidazole and b2) vinylpyrrolidone as monomers, use thereof and method using such a composition.Type: ApplicationFiled: December 17, 2019Publication date: June 18, 2020Applicant: Henkel AG & Co. KGaAInventors: JULIA BIBIANE LANGE, CYRIELLE MARTINEZ, DIANE METTEN
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Publication number: 20200188279Abstract: A cosmetic composition for temporarily reshaping keratin fibres, containing: a) a cationically modified guar derivative with a weight-average molecular weight in the range of from about 5,000 to about 200,000 and a degree of cationic substitution in the range of from about 0.1 to about 2 and b) at least one cationic copolymer, which is obtained by reacting vinylpyrrolidone with dimethylaminoethyl methacrylate, use thereof and method utilising such a composition.Type: ApplicationFiled: December 17, 2019Publication date: June 18, 2020Applicant: Henkel AG & Co. KGaAInventors: JULIA BIBIANE LANGE, CYRIELLE MARTINEZ, DIANE METTEN
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Publication number: 20200188280Abstract: A cosmetic composition for temporarily styling keratinous fibres, containing: a) at least one cationically modified guar derivative with a mass average molecular weight in the range from about 5000 to about 200000 and a cationic degree of substitution in the range from about 0.1 to about 2, and c) at least one vinylcaprolactam-containing copolymer, its use and a method using a composition of this type.Type: ApplicationFiled: December 17, 2019Publication date: June 18, 2020Applicant: Henkel AG & Co. KGaAInventors: JULIA BIBIANE LANGE, CYRIELLE MARTINEZ, DIANE METTEN
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Publication number: 20200188281Abstract: A photopolymerizable composition for forming a photopolymerized nail top coating of a substantially uniform mixture of ethyl cellulose and crosslinked (meth)acrylate polymer is disclosed.Type: ApplicationFiled: December 15, 2017Publication date: June 18, 2020Inventors: Elizabeta Pavlovic, Sunan Yuvavanich
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Publication number: 20200188282Abstract: Hair dyeing process comprising a phosphonic ethylenic polymer and a pigment The invention relates to a process for dyeing hair comprising at least one pigment and at least one phosphonic polymer derived from the polymerization of: (a) 45% to 95% by weight of ethylenic monomer bearing an at least Cs linear or branched alkyl group; (b) 5% to 25% by weight of vinylphosphonic acid monomer; (c) 0 to 50% by weight of additional monomer chosen from: (i) linear or branched C1-C6 alkyl (meth)acrylate or C6-C12 cycloalkyl (meth)acrylate non-silicone monomers; (ii) specific polydimethylsiloxane silicone monomers bearing a mono(meth)acryloyloxy end group.Type: ApplicationFiled: April 9, 2018Publication date: June 18, 2020Applicant: L'OREALInventor: Sandrine CHODOROWSKI-KIMMES
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Publication number: 20200188283Abstract: The invention relates to a hair dyeing process comprising at least one pigment, at least one additional component selected from cross linking agents and/or plasticizers and at least one block polymer comprising: a first block with a glass transition temperature (Tg) of greater than or equal to 40° C. derived from a monomer CH2?C(R1)—COOR2 in which R1=H or methyl, R2=C4 to C12 cycloalkyl group; and a second block with a glass transition temperature (Tg) of less than or equal to 20° C. derived from a vinylphosphonic acid and from a monomer CH2=C(R1)—COOR3 in which R1=H or methyl, R3=linear or branched C1 to C6 unsubstituted alkyl group, with the exception of a tert-butyl group or a methoxyethyl group.Type: ApplicationFiled: April 4, 2018Publication date: June 18, 2020Applicant: L'OREALInventor: Sandrine CHODOROWSKI-KIMMES
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Publication number: 20200188284Abstract: The present disclosure provides a silicone-free hair oil including one or more polyamides, one or more esters, one or more natural oils, one or more fatty alcohols, or a mixture thereof, and one or more hydrocarbons. The present disclosure also provides a method of using the silicone-free hair oil for the care of keratin fibres.Type: ApplicationFiled: November 15, 2019Publication date: June 18, 2020Applicant: Henkel AG & Co. KGaAInventors: TINA AHNFELDT, SYLVIA KERL
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Publication number: 20200188285Abstract: To provide an acrylic silicone graft copolymer capable of effectively exerting a function in a composition for external application containing various oily components such as a natural oil, a hydrocarbon oil, ester oil and a silicone oil, and a composition for external application containing the acrylic silicone graft copolymer. A composition for external application including an acrylic silicone graft copolymer, which contains 2 to 25 mass % of a constitutional unit represented by formula (I), 55 to 85 mass % of a constitutional unit represented by formula (II) and 2 to 20 mass % of a constitutional unit represented by formula (III). wherein R1 is an alkyl group having 1 to 4 carbon atoms; R2 is an alkylene group having 2 to 10 carbon atoms; and n is an integer of 1 to 100.Type: ApplicationFiled: August 8, 2017Publication date: June 18, 2020Inventors: Hideyuki YAMAKI, Tomomi KUROMIYA, Chikako ICHIKAWA, Hisao ITO, Mitsuhiro FUKUSHIMA, Yuki MUNEKATA
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Publication number: 20200188286Abstract: The present disclosure relates to an anhydrous hair oil which comprises a cosmetic oil and an emulsifier. The present disclosure also relates to a method which comprises a step in which a hair oil is applied to keratin fibers, in particular human hair, and which comprises a subsequent step in which the hair oil is rinsed out.Type: ApplicationFiled: November 20, 2019Publication date: June 18, 2020Applicant: Henkel AG & Co. KGaAInventors: JENS DELOWSKY, SYLVIA KERL
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Publication number: 20200188287Abstract: The present disclosure relates to a silicone-free cosmetic agent comprising: one or more polyamides, one or more esters; Ricinus Communis (Castor) Seed Oil, isostearyl alcohol, or a mixture thereof; and one or more hydrocarbons, and use thereof for the care of keratin fibres.Type: ApplicationFiled: November 25, 2019Publication date: June 18, 2020Applicant: Henkel AG & Co. KGaAInventors: TINA AHNFELDT, SYLVIA KERL
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Publication number: 20200188288Abstract: The invention is directed to a fingernail growth and protection system. The system provides a five-step process using all natural materials to grow and strengthen the nails for use with nail polish and other cosmetic treatments. The process supports the nail with a small paper wedge, trimmed to fit under the nail. The process further provides steps to grow and strengthen the user's nails with soaking, scrubbing, polishing, and oiling steps to produce longer and stronger nails.Type: ApplicationFiled: December 17, 2019Publication date: June 18, 2020Inventor: Marlyn Knight
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Publication number: 20200188289Abstract: The aspects presented herein provide improved flavor compositions, able to deliver long lasting cooling sensation without compromising on the safety profile towards the skin and/or mucosal membrane.Type: ApplicationFiled: May 15, 2018Publication date: June 18, 2020Applicant: Firmenich SAInventor: Patrice MERCERET
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Publication number: 20200188290Abstract: The present invention relates to a yarrow fresh plant press juice concentrate and a gentle method for its manufacture. The yarrow fresh plant press juice concentrate is used in cosmetic compositions, pharmaceutical compositions, food compositions or food supplements. This invention also relates to new aspects of the use of yarrow. The invention provides the use of yarrow to stimulate the expression of heat shock proteins and/or antimicrobial peptides in skin cells. It also describes the use of yarrow to increase the thermal tolerance of the skin.Type: ApplicationFiled: April 28, 2017Publication date: June 18, 2020Inventors: Martina HERRMANN, Sandra GAEBLER, Manuel PESARO, Dominik STUHLMANN, Lisa GARBE, Julia MEYER
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Publication number: 20200188291Abstract: Lipid-soluble, anti-pollution cosmetic compositions as well as cosmetic products comprising the same, are provided. The cosmetic compositions and cosmetic products are suitable for the treatment and prevention of signs of extrinsic aging, particularly caused by external aggressors from pollution.Type: ApplicationFiled: May 17, 2017Publication date: June 18, 2020Inventors: Priscila Carollo Moncayo, Juliana Carvalhães Lago, Soraya Baione de Moura
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Publication number: 20200188292Abstract: Disclosed are compositions and methods for their use for cosmetic applications. The composition can include tetrahexyldecyl ascorbate, Phyllanthus emblica fruit extract, and tocopherol, ascorbic acid. The composition can further include vegetable amino acids.. An effective amount of the composition can be applied on skin to stimulate collagen production and lysyl oxidase activity, inhibit tyrosinase, inhibit melanogenesis and/or COX-1 activity, and inhibit the matrix metalloproteinase enzyme activity in skin.Type: ApplicationFiled: December 6, 2019Publication date: June 18, 2020Inventors: Tiffany CARLE, Milagros SANCHEZ, David GAN
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Publication number: 20200188293Abstract: Provided herein is a personal care composition that can exhibit an increased vapor release while maintaining physical stability and texture. The personal care composition can contain from about 35% to about 90% petrolatum, from about 20% to about 50% of an olfactory composition, and a gelling agent mixture. The gelling agent mixture can contain dibutyl lauroyl glutamide, dibutyl ethylhexanoyl glutamide, and a solvent selected from the group consisting of pentylene glycol, propylene glycol, hexylene glycol, 3-methyl-1,3-butanediol, 3-methyl-1,2-butanediol, 1,5-pentanediol, and combinations thereof. The personal care composition can exhibit a vapor release of from about 35 mg to about 300 mg at 8 hours and can have an Instability Index of less than about 0.8.Type: ApplicationFiled: December 17, 2019Publication date: June 18, 2020Inventors: Stephen Bingham, Barbara Jackova, Joshua Hampton, Jason William Newlon, Jaspreet Singh Kochhar, Jayant Khanolkar, Aline Fornear
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Publication number: 20200188294Abstract: The present invention provides a conductive hydrogel comprising a polystyrene sulfonate compound selected from poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS), reduced graphene oxide polystyrene sulfonate (rGO:PSS) and rGO:PEDOT:PSS; and a conjugate of polyethylene glycol (PEG) and a linker-(BX)n oligopeptide of formula (I) PEG-linker-(BX)n ??(I) wherein B is lysine or arginine, X is selected from alanine, glycine, serine, threonine, tyrosine, glutamic acid or aspartic acid and n is an integer selected from 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19 and 20. The invention further relates to processes for assembling the conductive hydrogel. The conductive hydrogel can be used in various biomedical applications, such as neuroprostheses, biosensors, nerve grafts, cell culture and encapsulation of cells and microorganisms as well as for drug delivery.Type: ApplicationFiled: April 27, 2018Publication date: June 18, 2020Applicant: DENOVOMATRIX GMBHInventors: Yixin ZHANG, Yong XU, Alvin THOMAS
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Publication number: 20200188295Abstract: Disclosed are methods useful for the topical therapeutic treatment of skin malignancies including skin cancers and cutaneous metastases using compositions containing nanoparticles of paclitaxel or other taxanes.Type: ApplicationFiled: December 6, 2019Publication date: June 18, 2020Applicant: DFB SORIA, LLCInventor: Gere DIZEREGA
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Publication number: 20200188296Abstract: Disclosed herein is a new use of liquid pharmaceutical preparations comprising immune agonistic antibodies, resulting in improved tolerability/adverse event profile while at least maintaining the same level of biological activity of said immune agonist.Type: ApplicationFiled: November 27, 2019Publication date: June 18, 2020Applicant: Hoffmann-La Roche Inc.Inventors: Gonzalo Acuña, Emily Rana Corse, Jehad Charo, Martin Lechmann, Martin Stern
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Publication number: 20200188297Abstract: A topical ophthalmic formulation of an LXR agonist that could be used for treating dry-eye disease. Examples of LXR agonists that could be used include naturally occurring oxysterol compounds, such as ouabagenin or hyodeoxycholic acid, or synthetic, non-sterol compounds such as IMB-151 or T0901317. The LXR agonist compound may be encapsulated within biodegradable nanoparticles, such as poly(lactic/glycolic) acid (PLGA) nanoparticles, micelles, or liposomes. Experimental work establishing proof-of-concept has been performed.Type: ApplicationFiled: December 12, 2019Publication date: June 18, 2020Inventors: Simon Kaja, Anita Ghosh, Walter Keith Jones
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Publication number: 20200188298Abstract: A composition comprising surfactant-enhanced phospholipid vesicles with one or more cannabinoid substance encapsulated therein is disclosed, wherein one or more surfactant is utilized for enhancing loading and increasing encapsulation efficiency of cannabinoid passenger molecules within phospholipid structures. A method is disclosed for making a surfactant-enhanced phospholipid vesicles with one or more cannabinoid substance encapsulated therein, wherein one or more surfactant is used for enhancing loading and increasing encapsulation efficiency of passenger molecules in phospholipid structures. A method of using surfactant-enhanced phospholipid vesicles with one or more cannabinoid substance encapsulated therein is disclosed wherein one or more surfactant enhances loading and increases encapsulation efficiency of cannabinoid substances in phospholipid structures.Type: ApplicationFiled: December 6, 2019Publication date: June 18, 2020Applicant: NuVessl, Inc.Inventor: Jeffrey S. Reynolds
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Publication number: 20200188299Abstract: This invention relates to a method for treating a swallowing disorder in a patient suffering from aspiration before, during and/or after the swallowing reflex, and to a bolus for use in the treatment of a swallowing disorder in such a patient.Type: ApplicationFiled: February 20, 2020Publication date: June 18, 2020Inventors: Adam Burbidge, Jan Engmann, Kala Marie Kaspar, Michael Jedwab
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Publication number: 20200188300Abstract: A formulation comprising liposomes, wherein the liposomes comprise, based on the liposome, 0.7 to 3.0 mol % of eritoran or a pharmaceutically acceptable salt thereof and 0.5 to 3.0 mol % of a PEGylated phospholipid.Type: ApplicationFiled: December 13, 2019Publication date: June 18, 2020Applicant: Eisai R&D Management Co., Ltd.Inventors: Hiroshi Ishihara, Katsura Hata, Hiroki Muto, Geoff Hird
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Publication number: 20200188301Abstract: A composition comprising surfactant-enhanced phospholipid vesicles with one or more cannabinoid substance encapsulated therein is disclosed, wherein one or more surfactant is utilized for enhancing loading and increasing encapsulation efficiency of cannabinoid passenger molecules within phospholipid structures. A method is disclosed for making a surfactant-enhanced phospholipid vesicles with one or more cannabinoid substance encapsulated therein, wherein one or more surfactant is used for enhancing loading and increasing encapsulation efficiency of passenger molecules in phospholipid structures. A method of using surfactant-enhanced phospholipid vesicles with one or more cannabinoid substance encapsulated therein is disclosed wherein one or more surfactant enhances loading and increases encapsulation efficiency of cannabinoid substances in phospholipid structures.Type: ApplicationFiled: December 6, 2019Publication date: June 18, 2020Applicant: NuVessl, Inc.Inventor: Jeffrey S. Reynolds
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Publication number: 20200188302Abstract: The purpose of the present invention is to provide a method for producing granules of having a uniform size. To this end, the present invention provides a method for producing granules, the method characterized by including preparing an organic member solution, uniformly dispersing an inorganic member in the organic member solution at a weight ratio of 1 to 10 based on an organic member to form an organic-inorganic composite solution, spraying the organic-inorganic composite solution in an electrostatic charge manner, and polymerizing the sprayed organic-inorganic composite solution to form a hydrogel phase. The production method of the present invention has advantages in that granules having a uniform size may be mass-produced in a short time and the granules may be produced at a high yield.Type: ApplicationFiled: October 10, 2019Publication date: June 18, 2020Applicant: Korea Institute of Machinery & MaterialsInventors: Hui Suk YUN, Honghyun Park
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ACTIVE INGREDIENT CONTAINING STABILISED SOLID MEDICINAL FORMS AND METHODS FOR THE PRODUCTION THEREOF
Publication number: 20200188303Abstract: The invention relates to solid medicinal forms containing at least one active ingredient and at least one pharmaceutically compatible, water soluble drying agent which is selected from the group consisting of trimagnesium dicitrate and/or calcium chloride, the solid medicinal form having a drying loss of at most 6% and a relative equilibrium moisture content of 25% or less. The invention also relates to solid medicinal forms containing a moisture-sensitive active ingredient and trimagnesium dicitrate.Type: ApplicationFiled: February 20, 2020Publication date: June 18, 2020Applicant: Losan Pharma GmbHInventors: Peter GRUBER, Dirk Spickermann