Abstract: The invention relates to human homeobox transcription factor VentX and its regulation of differentiation and maturation of human dendritic cells, and related therapeutic and diagnostic compositions and methods of use.

Abstract: Disclosed herein is a system and method for increasing the fidelity of measured genetic data, for making allele calls, and for determining the state of aneuploidy, in one or a small set of cells, or from fragmentary DNA, where a limited quantity of genetic data is available. Poorly or incorrectly measured base pairs, missing alleles and missing regions are reconstructed using expected similarities between the target genome and the genome of genetically related individuals. In accordance with one embodiment, incomplete genetic data from an embryonic cell are reconstructed at a plurality of loci using the more complete genetic data from a larger sample of diploid cells from one or both parents, with or without haploid genetic data from one or both parents. In another embodiment, the chromosome copy number can be determined from the measured genetic data, with or without genetic information from one or both parents.

Abstract: The present application generally to the diagnosis and treatment of diseases resulting from the alteration of chromatin boundaries between topologically-associated domains. In particular, the present application relates to detection of mutations causing DNA hypermethylation phenotypes, CpG methylation within CTCF binding motifs, and aberrant gene expression caused by altered chromatin topology. Applicants show that IDH mutant gliomas exhibit hyper-methylation at CTCF binding sites, compromising binding of this methylation-sensitive insulator protein. Applicants also demonstrate that loss of CTCF at a domain boundary permits a constitutive enhancer to aberrantly interact with the receptor tyrosine kinase gene PDGFRA, a prominent glioma oncogene. Thus, Applicants have uncovered that IDH mutations may promote gliomagenesis by disrupting chromosomal topology and allowing aberrant regulatory interactions that induce oncogene expression.

Abstract: The present invention discloses the use of miR-4714, miR-4521, and miR-1292 as diagnostic markers for osteosarcoma. High-throughput sequencing and QPCR experiments prove that the levels of miR-4714, miR-4521, and miR-1292 in the blood of normal and osteosarcoma patients are significantly different, and therefore miR-4714, miR-4521, and miR-1292 can be used as a molecular marker for the diagnosis of osteosarcoma for developing products for the diagnosis of osteosarcoma. The diagnostic product has the following advantages: non-invasive, rapid, sensitive, and has broad application prospects in clinical practice.

Abstract: The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to ncRNAs as diagnostic markers and clinical targets for prostate, lung, breast and pancreatic cancer.

Abstract: The present disclosure is related to a developing method of candidate probes and a using method thereof. Specifically, the candidate probes are capable binding specific genes and further identifying a cell type of a tissue. Briefly, the developing method comprises the steps of: (a) using a chip to generate gene expressions of normal samples with known organ; (b) using a processing module to compare the gene expressions of the normal samples; and (c) developing candidate probes based on the previous comparing results. The using method comprises the steps of: (a?) using the previous candidate probes to detect the relative gene expression in a test sample with an unknown cell type; (b?) using a processing module to analysis the score of the test sample; and (c?) further predict the cell type of the test sample. Moreover, the present disclosure further provides a system used to conduct the above method, and the system comprises a detecting chip including an array with the candidate probes and a processing module.

Abstract: Provided herein is technology relating compositions and methods for detecting tissue cell-specific DNA, such as epithelial cell-specific DNA, in blood or blood products from a subject. The technology also relates to use of tissue cell-specific DNAs as internal controls for methylation assays.

Abstract: The invention provides methods for evaluating disease, such as cancer, by way of performing multiple assays involving single-cell analysis on live cells isolated from a sample of a patient. The data obtained from the multiple assays is analyzed and linked to thereby provide a characterization of any given cell having undergone analysis, which, in turn, allows for evaluation of the sample either known to be, or suspected of being, cancerous. A report may be generated based on the data analysis, wherein the report provides information related to the cancer evaluation, including, but not limited to, whether the sample tested positive for cancer, a determination of a stage or progression of cancer, and a customized treatment plan tailored to an individual patient's cancer diagnosis.

Abstract: Methods and systems for quantification of a target nucleic acid in a sample are provided. The method includes forming a plurality of discrete sample portions. Each of the plurality of discrete sample portions comprising a portion of the sample, and a reaction mixture. The method further includes amplifying the plurality of discrete sample portions to form a plurality of discrete processed sample portions. At least one discrete processed sample portion containing nucleic acid amplification reaction products. Fluorescence signals are detected from the at least one of the plurality of discrete processed sample portions to determine a presence of the at least one target nucleic acid. The method also includes determining the respective volumes of the plurality of the plurality of discrete processed sample portions, and estimating the number of copies-per-unit-volume of the at least one target nucleic acid in the sample.

Abstract: The present invention relates to methods, kits and systems for the prognosis of the disease outcome of breast cancer, said method comprising: (a) determining in a tumor sample from said patient the RNA expression levels of at least 2 of the following 9 genes: UBE2C, BIRC5, RACGAP1, DHCR7, STC2, AZGP1, RBBP8, IL6ST, and MGP (b) mathematically combining expression level values for the genes of the said set which values were determined in the tumor sample to yield a combined score, wherein said combined score is indicative of a prognosis of said patient; and kits and systems for performing said method.

Abstract: In one aspect provided herein are methods of determining a triple negative breast cancer (TNBC) subtype in an individual in need thereof comprising determining expression of one or more genes in one or more TNBC cells of the individual; and comparing the expression of the one or more genes in the TNBC cells with the expression of the one or more genes in a control. In another aspect, the methods are directed to determining a treatment protocol for the TNBC patient based on the TNBC subtype. In another aspect, the methods are directed to predicting whether an individual will benefit from a treatment for a particular TNBC subtype. In yet another aspect, the invention is directed to a method of determining whether an agent can be used to treat a TNBC subtype.

Abstract: Described herein is a redox biosensor system for measurement of NADH/NAD+ ratio including a host strain or cell-free system including first and a second expression cassette; the first expression cassette including, in operable communication, a constitutive promoter and a gene encoding a Rex allosteric transcription factor that regulates gene expression by binding to NAD(H); and the second expression cassette including, in operable communication, a promoter regulated by the Rex allosteric transcription factor, and a gene encoding a reporter protein, wherein the first expression cassette expresses the Rex allosteric transcription factor, and, in the presence of NAD(H), the Rex allosteric transcription factor drives expression of the reporter protein from the second expression cassette, and wherein the expression of the reporter protein is proportional to the NADH/NAD+ ratio.

Abstract: Compositions comprising C5 and C6 monosaccharides and low levels of undesirable impurities, such as compounds containing sulfur, nitrogen, or metals, are disclosed.

Abstract: A raw material for direct reduction which is reduced in a shaft furnace includes a raw material, and a coating layer which coats the raw material and has a porosity of 20 volume % or more.

Abstract: After an first heat treatment step, an ambient temperature of a stack is held so that the stack is kept in a temperature range that allows the stack to be crystallized by heating the end of the stack to a second temperature range in the second heat treatment step; and a following expression (1) is satisfied, where Q1 represents an amount of heat required to heat the stack to the first temperature range in the first heat treatment step, Q2 represents an amount of heat that is applied to the stack when heating the end of the stack to the second temperature range in the second heat treatment step, Q3 represents an amount of heat that is released during crystallization of the stack, and Q4 represents an amount of heat required to heat the entire stack to the crystallization start temperature Q1+Q2+Q3?Q4??(1).

Abstract: A method is for producing a high strength coated steel sheet having an improved ductility and an improved formability, and a chemical composition containing: 0.13%?C?0.22%, 1.9%?Si?2.3%, 2.4%?Mn?3%, Al?0.5%, Ti?0.05%, Nb?0.05%, the remainder being Fe and unavoidable impurities. The sheet is annealed at temperature TA higher than Ac3 but less than 1000° C. for a time of more than 30 s, quenched by cooling to a quenching temperature QT between 200° C. and 280° C. in order to obtain a structure consisting of austenite and at least 50% of martensite, the austenite content being such that the final structure can contain between 3% and 15% of residual austenite and between 85% and 97% of the sum of martensite and bainite, without ferrite, heated up to a partitioning temperature PT between 430° C. and 490° C. and maintained at this temperature for a time Pt between 10 s and 100 s, hot dip coated and cooled to the room temperature.

Abstract: A predetermined composition is had, when a C content is represented by (C %), in a case of (C %) being not less than 0.35% nor more than 0.65%, a volume fraction of pearlite is 64×(C %)+52% or more, and in a case of (C %) being greater than 0.65% and 0.85% or less, the volume fraction of pearlite is not less than 94% nor more than 100%, and a structure of the other portion is composed of one or two of proeutectoid ferrite and bainite. Further, in a region to a depth of 1.0 mm from a surface, a volume fraction of pearlite block having an aspect ratio of 2.0 or more is not less than 70% nor more than 95%, and a volume fraction of pearlite having an angle between an axial direction and a lamellar direction on a cross section parallel to the axial direction of 40° or less is 60% or more with respect to all pearlite.

Abstract: A method for predicting a martensitic transformation rate and a method for setting processing conditions capable of improving the accuracy of a prediction of a martensitic transformation rate when a steel material is subjected to deformation processing as well as to heat treatment are provided. A method for predicting a martensitic transformation rate according to an embodiment includes predicting a rate of a transformation to a martensitic phase that appears when a steel material is subjected to deformation processing as well as to heat treatment in which a temperature of the steel material is changed, in which a martensitic transformation rate Vm is calculated by using a prediction formula, the method further including identifying parameters m and n of the prediction formula, and calculating the martensitic transformation rate at a predetermined temperature and a predetermined strain rate by using the prediction formula into which the identified parameters are substituted.

Abstract: A process for recovery of one or more elements, selected from precious metals and chalcophile metals as herein defined, from materials containing precious and/or chalcophile metal/s, said process including: (i) a leaching step comprising contacting the material with an acidic solution containing a lixiviant comprising an aqueous amino acid-thiourea compound formed from an amino acid (as herein defined) and thiourea (as herein defined), in order to form a leachate containing the precious metal and/or chalcophile metal; and (ii) a recovery step comprising recovering the precious metal and/or chalcophile metal from the leachate.

Abstract: The present invention relates to a method for extracting base and precious metals, all contained in refractory minerals, using aqueous media. The aim is to replace the current “flotation/smelting”-method for extracting minerals in Chilean and global mining or classical leaching with a method comprising a simple and robust pre-treatment that leads to solubilisation of the refractory matrices thereof. The method consists of mixing the mineral (Cu2S, CuS,CuFeS2, Cu5FeS4, FeS2, FeAsS.NiS, (Ni,Fe)xSy), ground to an appropriate size (2.

Abstract: The present disclosure broadly relates to a process for recovering scandium and/or vanadium values from various feedstocks. More specifically, but not exclusively, the present disclosure relates to a process for the selective recovery of scandium and/or vanadium values from a feedstock, the process comprising: leaching the feedstock in a sulfuric acid solution while simultaneously sonicating the sulfuric acid solution thereby producing a pregnant solution; and selectively removing scandium and vanadium compounds from the pregnant solution using a solvent extraction process.

Abstract: The invention relates to a resistor alloy (3) for an electrical resistor, in particular for a low-resistance current-measuring resistor, having a copper constituent, a manganese constituent and a nickel constituent. According to the invention, the manganese constituent has a mass fraction of 23% to 28%, while the nickel constituent has a mass fraction of 9% to 13%. The mass fractions of the alloy constituents are adjusted to one another in such a manner that, compared to copper, the resistor alloy (3) has a low thermal electromotive force at 20° C. of less than ±1??/K. The invention furthermore includes a component made from such a resistor alloy and a production method therefor.

Abstract: A hot rolled steel sheet according to an aspect of the present invention has a predetermined chemical composition, and a metallographic structure in which martensite is the major structure, wherein an average length of grains in an L direction parallel to a rolling direction is 0.2 ?m or more and 5.0 ?m or less, an average length of grains in a C direction parallel to a transverse direction is 0.1 ?m or more and 5.0 ?m or less, the ratio of the average length in the C direction to the average length in the L direction is 0.2 or more and 5.0 or less, and the tensile strength is 1180 MPa or more.

Abstract: The invention relates to a hot-forming material composed of a three-layer composite material, comprising a core layer of a hardenable steel which in the press-hardened state has a tensile strength >1600 MPa and/or a hardness >490 HV10, more particularly a tensile strength >1700 MPa and/or a hardness >520 HV10, and two outer layers bonded substance-to-substance with the core layer and composed of a soft steel which has a tensile strength corresponding at most to one quarter of the tensile strength of the core layer in the press-hardened state, and provided on one or both sides with an anticorrosion coating, more particularly an aluminum-based coating. The invention further relates to a component and also to a corresponding use.

Abstract: When a Si content (mass %) is set to [Si], an Al content (mass %) is set to [Al], and a Mn content (mass %) is set to [Mn], a parameter Q represented by “Q=[Si]+2[Al]?[Mn]” is 2.00 or more, the total mass of S contained in sulfides or oxysulfides of Mg, Ca, Sr, Ba, Ce, La, Nd, Pr, Zn, or Cd is 40% or more of the total mass of S contained in a non-oriented electrical steel sheet, a {100} crystal orientation intensity is 3.0 or more, a thickness is 0.15 mm to 0.30 mm, and an average crystal grain diameter is 65 ?m to 100 ?m.

Abstract: A method for manufacturing a hot-rolled and coated steel sheet having a thickness between 1.8 mm and 5 mm. The method contains the steps of: providing a semi-product having a composition containing: 0.04%?C?0.38%, 0.40%?Mn?3%, 0.005%?Si?0.70%, 0.005%?Al?0.1%, 0.001%?Cr?2%, 0.001%?Ni?2%, 0.001%?Ti?0.2%, Nb?0.1%, B?0.010%, 0.0005%?N?0.010%, 0.0001%?S?0.05%, 0.0001%?P?0.1%, Mo?0.65%, W?0.30%, Ca?0.006%, hot-rolling with a final rolling temperature FRT, to obtain a hot-rolled steel product having a thickness between 1.8 mm and 5 mm, then cooling down to a coiling temperature Tcoil satisfying: 450° C.

Abstract: Disclosed is an iron-based amorphous alloy FeaBbSicREd, wherein a, b, and c represent, in atomic percentages, the contents of corresponding components, respectively; 83.0?a?87.0, 11.0<b<15.0, 2.0?c?4.0, and a+b+c=100; and d is the concentration of RE in the iron-based amorphous alloy, i.e. 10 ppm?d?30 ppm. The iron-based amorphous alloy has a saturation magnetic induction intensity of no less than 1.63 T, and same can be used to manufacture a magnetic core material for power transformers, motors and inverters.

Abstract: Method of manufacturing aluminium alloy rolled sheet product with excellent formability and good paint bake hardenability, including: casting Al—Si—Mg aluminium alloy ingot including, in wt. %: Si 1.0% to 1.50%, Mg 0.10% to 0.40%; heating the ingot to above 550° C.; maintaining the ingot above 550° C. for at least about 4 hours; cooling the ingot to 460° C. to 520° C. Maintaining the ingot at 460° C. to 520° C. for less than 6 hours. Hot-rolling the ingot in one or more rolling steps to intermediate gauge of 15 to 40 mm. The hot-mill exit temperature is 370° C. to 480° C. Further hot-rolling from intermediate gauge in one or more rolling steps to final hot rolling gauge. The hot-mill exit temperature is 310° C. to 400° C. Cooling the hot-rolled material at hot rolling final gauge from hot-mill exit temperature to ambient temperature. Cold rolling the hot-rolled product to a cold-rolled product of final gauge.

Abstract: The present invention relates to a method of hot dip coating of flat steel products, comprising a step of stripping the coated steel strip by means of at least one nozzle that emits a stripping gas having a temperature T3 at an angle ? in the direction of the coated steel strip, wherein the angle ?, the distance h between the surface of the melt bath and the lower edge of the nozzle in mm, the temperature of the stripping gas in ° C. and the differential between the temperature T2 of the melt bath and the temperature T1 of the steel strip are in a particular relationship to one another, and to a correspondingly produced hot dip-coated flat steel product.

Abstract: A hot-dip aluminum-coated steel wire including a steel wire having a diameter of 0.1 to 0.4 mm on which a plating layer is formed, wherein an elongation at break of the hot-dip aluminum-coated steel wire is 5 to 30%, and a ratio of an average diameter of the steel wire which is taken out from the hot-dip aluminum-coated steel by removing the plating layer per 100 mm in length of the steel wire to the minimum diameter of the steel wire satisfies the formula: [minimum diameter/average diameter]?[1?(elongation at break (%)/100)], and a method for producing a hot-dip aluminum-coated steel wire including wire-drawing a hot-dip aluminum-coated steel wire so that a ratio of an average diameter of the steel wire which is taken out from the hot-dip aluminum-coated steel by removing the plating layer per 100 mm in length of the steel wire to the minimum diameter of the steel wire satisfies the above-mentioned formula, and an elongation at break of the hot-dip aluminum-coated steel wire is 5 to 30%.

Abstract: There is provided a method for manufacturing a soft magnetic member where a coating formed of an ?-Fe2O3 single phase having a high electrical resistivity is formed on a soft magnetic alloy substrate. A soft magnetic alloy substrate is heated in an atmosphere containing water vapor and inert gas to form a coating on the soft magnetic alloy substrate. The atmosphere has an oxygen partial pressure in a range of 0 to 1.5 kPa. A soft magnetic member including the soft magnetic alloy substrate and the coating formed on its surface can be obtained.

Abstract: An exterior material of a home appliance having improved corrosion resistance and fingerprint resistance by changing a treatment method of a surface of the exterior material, and the home appliance including the same, and a manufacturing method therefor are provided. The method of manufacturing the exterior material of the home appliance, the method including applying a diamond like carbon (DLC) coating on the substrate to form a DLC coating layer; and conducting anti-fingerprint coating to form the anti-fingerprint coating on the DLC coating layer.

Abstract: An object to be achieved by the present invention is to provide a gas barrier film having excellent acid resistance, transparency, and gas barrier properties. The gas barrier laminated body of the present invention is a laminate, in which an inorganic thin-film layer is laminated onto at least one of surfaces of a polymer substrate, and the inorganic thin-film layer mainly contains Al and Si, and a ratio of an Al content amount between before and after treatment of immersing the laminate into aqueous solution of hydrochloric acid that has concentration of 1 mol/L for one hour satisfies a formula of (Al Content Amount After Treatment)/(Al Content Amount Before Treatment)×100?75.

Abstract: A deposition system for depositing evaporated material on a substrate is described. The deposition system includes a vapor source having one or more vapor outlets; a shield; and a cooling device for cooling the shield, wherein the vapor source is movable to an idle position in which the one or more vapor outlets are directed toward the shield. Further, a deposition apparatus with a deposition system as well as a method of operating a deposition system are described.

Abstract: The disclosure relates to a method of determining a velocity profile for the movement of a substrate to be coated relative to a coating source.

Abstract: Devices having an air bearing surface (ABS), the device including a near field transducer, the near field transducer having a peg and a disc, the peg having a region adjacent the ABS, the peg including a plasmonic material selected from gold (Au), silver (Ag), copper (Cu), ruthenium (Ru), rhodium (Rh), aluminum (Al), or combinations thereof; and at least one other secondary atom selected from germanium (Ge), tellurium (Te), aluminum (Al), antimony (Sb), tin (Sn), mercury (Hg), indium (In), zinc (Zn), iron (Fe), copper (Cu), manganese (Mn), silver (Ag), chromium (Cr), cobalt (Co), and combinations thereof, wherein a concentration of the secondary atom is higher at the region of the peg adjacent the ABS than a concentration of the secondary atom throughout the bulk of the peg. Methods of forming NFTs are also disclosed.

Abstract: A reaction chamber includes a reactor wall, a susceptor contacting the reactor wall to define a reaction space and a gas flow control device and a showerhead member stacked between the reactor wall and the susceptor. The showerhead member includes a gas channel and a showerhead. Penetration holes are formed through a protruding lateral portion of the gas flow control device, and the reactor wall and a lateral portion of the showerhead member are spaced apart from each other to form a gas discharge path. Gas remaining in the gas discharge path is discharged through the penetration holes and a gas outlet formed in an upper portion of the reactor wall. Because of the reaction space and the gas discharge path, unnecessary regions are removed to rapidly change gases from one to another, and thus atomic layer deposition may be performed with high efficiency and productivity.

Abstract: A flange, flange assembly, and reactor system including the flange and flange assembly are disclosed. An exemplary flange assembly includes heated and cooled sections to independently control temperatures of sections of the flange. Methods of using the flange, flange assembly and reactor system are also disclosed.

Abstract: Aspects of the present disclosure relate generally to pedestals, components thereof, and methods of using the same for substrate processing chambers. In one implementation, a pedestal for disposition in a substrate processing chamber includes a body. The body includes a support surface. The body also includes a stepped surface that protrudes upwards from the support surface. The stepped surface is disposed about the support surface to surround the support surface. The stepped surface defines an edge ring such that the edge ring is integrated with the pedestal to form the body that is monolithic. The pedestal also includes an electrode disposed in the body, and one or more heaters disposed in the body.

Abstract: A method for selectively depositing a metal oxide film is disclosed. In particular, the method comprises pulsing a metal or semi-metal precursor onto the substrate and pulsing an organic reactant onto the substrate. A reaction between the metal or semi-metal precursor and the organic reactant selectively forms a metal oxide film on either a dielectric layer or a metal layer.

Abstract: A method of depositing a thin film of lead titanate (PTO), lead zirconate (PZO) or lead zirconate titanate (PZT) comprising depositing a PTO, PZO or PZT layer upon a substrate whereby growth occurs primarily due to self-limited surface chemisorption of pulsed chemical vapor, and annealing the PTO, PZO, or PZT layer and substrate.

Abstract: Exemplary semiconductor processing chamber showerheads may include a dielectric plate characterized by a first surface and a second surface opposite the first surface. The dielectric plate may define a plurality of apertures through the dielectric plate. The dielectric plate may define a first annular channel in the first surface of the dielectric plate, and the first annular channel may extend about the plurality of apertures. The dielectric plate may define a second annular channel in the first surface of the dielectric plate. The second annular channel may be formed radially outward from the first annular channel. The showerheads may also include a conductive material embedded within the dielectric plate and extending about the plurality of apertures without being exposed by the apertures. The conductive material may be exposed at the second annular channel.

Abstract: In a flow down type surface treating apparatus, a scattering amount of a processing solution Q is reduced. A honeycomb member 60 is provided vertically below a transport hanger 16. The honeycomb member 60 consists of a plurality of tubular members with hexagonal holes connected together. When the processing solution Q falls in a vertical direction (in the direction of an arrow ?), the processing solution Q passes through through-holes of the honeycomb member 60. When the processing solution Q hits liquid level H, a part of it is reflected. Since a part of the reflected processing solution Q is reflected obliquely, it collides with an inner wall of the through-hole of the honeycomb member 60. As a result, the amount of the treatment liquid Q that emerges again on an upper surface of the through-holes is reduced. Thereby, the honeycomb member 60 exhibits a scattering prevention function.

Abstract: In a flow down type surface treating apparatus, a scattering amount of a processing solution is reduced. A film forming mechanism 110 is provided on an inlet side and an outlet side of each treatment chamber. The film forming mechanism 110 ejects a continuous laminar liquid under pressure of about 0.01 MPa at a flow rate of 5 to 10 L/min. Such a liquid film prevents droplets reflected on a surface of an antiscattering member 60 from splashing and entering the adjacent treatment chamber. When a plate-like work 10 is shaken to collide with the liquid film, the film flows down along the plate-like work 10 since the film formed by the film forming mechanism 110 is liquid. Thereby, a shake of the plate-like work 10 is converged. An amount of air flowing in toward a transport direction in each treatment chamber is reduced.

Abstract: A hydrophobic coating and a method for applying such a coating to a surface of a metallic substrate. The method can include anodizing a nanoporous layer of anodic metal oxide on the surface; cathodizing yttrium oxide nanoparticles onto the surface; applying a hydrophobic ceramic coating composition to the surface by an application method selected from the group consisting of: flowing, dipping, and spraying; and heating the coated surface at a cure temperature from about 150° C. to about 300° C. for at least 2 hours.

Abstract: A piston ring includes an annular body, a wear-resistant layer that is applied to the annular body by thermal spraying, and a strain-hardened run-in layer, made of an AlCuFe alloy, that is applied to the wear-resistant layer by thermal spraying.

Abstract: A device comprising: a substrate; a first coating deposited on the substrate; an intermediate coating deposited on the first coating, wherein the first coating is interposed between the substrate and the intermediate coating; and a second coating deposited on the intermediate coating, wherein the intermediate coating is interposed between the first coating and the second coating, and the second coating is outermost and black. The substrate, the first coating, the intermediate coating and the second coating define at least one of a jewelry item and a component of a jewelry item.

Abstract: The present invention provides a flexible hard composite coating, a preparation method thereof and a coated cutter. The flexible hard composite coating includes an AlCrN transition layer and a nanocomposite layer sequentially disposed on the surface of a substrate, the nanocomposite layer having CrON layers and AlON layers sequentially alternately arranged on the surface of the AlCrN transition layer. According to an embodiment, AlCrN is used as a transition layer, for strengthening the connection between the nanocomposite layer and the substrate. The nanocomposite layer constituted by the CrON layers and the AlON layers increases the toughness of the coating and the successive alternation of the CrON layers and the AlON layers reduces the stress of the coating, increasing the crystal plane structure and the grain boundary of the coating and further improves the properties of hardness and resistance to high-temperature oxidation.

Abstract: An anticorrosion treatment method for a copper-containing material comprises: carrying out a sealed and pressurized reaction on a copper-containing material and a stabilizer in presence of a polar solvent and any assistant, the stabilizer being a compound capable of providing formates, so that the formates are adsorbed on the surface of the copper-containing material. In the method, formates are modified on the surface of the copper-containing material, accordingly, the oxidation resistance capability and the stability of the copper-containing material can be significantly improved while the electrical conductivity of the copper-containing material is not reduced, and the corrosion resistance of the copper-containing material and especially, the salt and alkali corrosion resistance of the copper-containing material are significantly improved.

Abstract: Method of minimizing pitting corrosion at temperatures above 130° C., wherein said method comprises: providing an acidic fluid comprising an alkylsulfonic acid; providing at least one corrosion inhibitor compound comprising an organic compound comprising at least two aldehyde functional groups; combining said acidic fluid with said at least one corrosion inhibitor compound; exposing said mixed fluid to a metallic surface at a temperature of at least 130° C.; and allowing said mixed fluid sufficient time of exposure to a metal to accomplish a pre-determined function.