Abstract: A system for performing minimally invasive procedures in a working space within a body lumen of a patient including a flexible catheter configured to receive a working instrument therethrough. The flexible catheter has a working space expanding system positioned at the distal portion, the working space expanding system including first and second flexible elements movable from a non-expanded insertion position to an expanded position forming an expanded region to expand the working space within the body. The first and second flexible elements are connected at a distal region by a coupling structure. A stabilizing member stabilizes the distal portion of the flexible catheter.

Abstract: Insufflation is currently considered to be a necessary part of an endoscopic procedure. However, it introduces risks and costs that would be beneficial to eliminate. The endoscopic assistance devices and methods disclosed herein facilitate the performance of endoscopic procedures without insufflation. The devices attach directly or indirectly to the distal end portion of the endoscope. One or more resilient, curved bars extend from the attachment point around an internal void space to form a resilient, curved cage that spreads tissue gently during the advance of the endoscope. The resilient, curved bars define the windows of the cage that enable the visualization of the internal anatomy via a lens on the distal face of the endoscope and the passage of treatment devices from the operative channel of the endoscope.

Abstract: In some embodiments, an ophthalmic laser system may be provided that does not include a traditional laser console. Instead, the treatment device may be configured to house the treatment light source within the device handle. Additionally, in some embodiments, the handheld treatment device may include a user interface, such as dials and buttons, for adjusting various parameters of the therapeutic light. With certain embodiments, the self-contained handheld treatment device may be operated independent of an AC power source. For example, in some embodiments, the handheld treatment device may be battery powered. Additionally, the handheld treatment device may be disposable or may utilize replaceable distal tips in certain embodiments. Certain embodiments may be particularly designed for transscleral cyclophotocoagulation. Also, treatment guides are provided that may be configured to couple with a treatment device to align the device with a target tissue of the eye.

Abstract: A system automatically captures a fundus image with limited user interaction such that the fundus image has one or more desired characteristics. The system can retrieve at least one image from an image capture device, process the at least one image digitally to generate a processed image, detect at least one point of interest in the processed image, determine that each of the at least one point of interest is representative of a corresponding feature of the eye, and obtain a fundus image of the eye based on the at least one image.

Abstract: Disclosed herein are system and method for testing and analysis of visual acuity and changes using an acuity model, the acuity model generated based on one or more acuity chart design parameters and candidate acuity parameters calculated using the acuity test data of the subject, the acuity model comprising a chart-specific psychometric function determined using a family of multiple-optotype psychometric functions, and wherein the acuity model is configurable to estimate possibility of obtaining the acuity test data of the subject.

Abstract: Embodiments of the present invention comprises apparatuses and methods of measuring levels of neurological impairment. Certain embodiments of the invention comprise a headset that emits light into the user's eyes and the system tracks the pupils' orientation, movement, contraction and dilation. In specific embodiments, the headset can run a battery of tests and calculate a score indicating the user's level of neurological impairment.

Abstract: Computer aided visualization and diagnosis by volume analysis of optical coherence tomography (OCT) angiographic data. In one embodiment, such analysis comprises acquiring an OCT dataset using a processor in conjunction with an imaging system; evaluating the dataset, with the processor, for flow information using amplitude or phase information; generating a matrix of voxel values, with the processor, representing flow occurring in vessels in the volume of tissue; performing volume rendering of these values, the volume rendering comprising deriving three dimensional position and vector information of the vessels with the processor; displaying the volume rendering information on a computer monitor; and assessing the vascularity, vascular density, and vascular flow parameters as derived from the volume rendered images.

Abstract: An ophthalmological microscope system, having an illumination system that projects illumination light onto a subject's eye. A light receiving system guides returning light of the illumination light to an image sensor or an eyepiece system. An interference optical system splits light into measurement light and reference light and detects interference light generated from returning light of the measurement light and the reference light. A designation unit is used for designating an operation mode. When an observation priority mode (or an OCT priority mode) has been designated, a controller executes first light amount control that restricts light amount of the measurement light (or second light amount control that restricts light amount of the illumination light) to make total light amount of the illumination light and the measurement light equal to or less than a predetermined value.

Abstract: A device for determining the distance of an eye of a user from the image capturing device is disclosed. The device includes a lighting device that is arranged at a specified position relative to the image capturing device and is designed to generate at least one specular light reflection, which has a linear portion, on the cornea of the eye of the user. The device also includes an image capturing device designed to capture at least one image of the specular light reflection in the region of the cornea of the at least one eye of the user. A distance determining device is designed to ascertain data relating to the distance between two specified points of the light reflection and the curvature of the at least one linear portion of the light reflection in the captured image and the distance of the eye from the image capturing device.

Abstract: A method for providing a personalized evaluation of CAD for a patient includes acquiring one or more non-invasive images depicting a patient's coronary arteries and extracting a first set of features of interest from the one or more non-invasive images. A machine learning model is applied to the first set of features of interest to yield a prediction of one or more coronary measures of interest. One or more invasive images depicting the patient's coronary arteries are acquired and a second set of features of interest are extracted from the one or more invasive images. The first set of features of interest and the second set of features of interest are combined to yield a combined set of features of interest. Then, the machine learning model may be applied to the combined set of features of interest to yield an enhanced prediction of the coronary measures of interest.

Abstract: A dental light irradiation device has sensing means for sensing a change of a position of the device, and an indicator for physically indicating the position change. The invention helps controlling the positioning of the device during use.

Abstract: Systems and methods for estimating the location of a wave source based upon low frequency measurements acquired using multiple receivers. In one aspect, a method for estimating an end range of a radiation beam delivered to a target is provided. The method includes controlling a radiation treatment system to deliver a radiation beam inducing at least one low frequency thermoacoustic wave inside a target, and detecting, using receivers positioned about the target, sonic signals corresponding to the at least one low frequency thermoacoustic wave. The method also includes analyzing the sonic signals to determine differences in times-of-flight associated with different receivers, and estimating an end range of the radiation beam by correlating the differences in times-of-flight. The method further includes generating a report indicative of the end range of the radiation beam.

Abstract: A subject is avascularized while changing the avascularization pressure between the avascularized condition and the non-avascularized condition. A receiving circuit receives a detection signal obtained by detecting a photoacoustic wave generated in the subject by emission of measurement light to the subject. Photoacoustic image generating circuitry generates a photoacoustic image based on the detection signal of the photoacoustic wave. The motion of each of a plurality of control points set in each photoacoustic image is detected based on photoacoustic images at a plurality of times. A region of interest is set based on the motion detected at each control point. Blood flow information is generated based on the signal strength of the photoacoustic image in the region of interest.

Abstract: A puncture needle is at least partially inserted into a subject. An optical fiber guides light with a first wavelength and an optical fiber guides light with a second wavelength. The light guided by the optical fiber is emitted from a first light emitting portion and the light guided by the optical fiber is emitted from a second light emitting portion. A light absorption member absorbs the light with the first wavelength emitted from the first light emitting portion to generate photoacoustic waves and transmits the light with the second wavelength emitted from the second light emitting portion.

Abstract: A system configured to determine a characteristic of a patient includes a plurality of sensors, wherein each sensor of the plurality of sensors is configured to noninvasively determine a respective parameter of the patient, and wherein the parameter determined by each sensor is different from parameters determined by remaining sensors of the plurality of sensors. Such a system also includes a connector having a passage configured to direct pressurized fluid therethrough, wherein the plurality of sensors is connected to the connector.

Abstract: Systems and methods are provided in which data acquisition device detects and captures ambulatory radial arterial blood pressure in a non-invasive and continuous manner through the combined use of tonometry, accelerometry and photoplethysmography, together with the detecting and translating of Mayer waves. Transformed blood pressure data, together with motion and contextual data can be used as input for machine learning algorithms and biomathematical models which can predict the general state of health of an individual. Transformed blood pressure data, together with motion and contextual data, may be communicated via wireless communications to mobile devices and/or cloud based platforms.

Abstract: The present disclosure relates to a device and method for acquiring and processing sensor signals on a host device. The device comprises a jack and connects to a socket on the host device. The device further comprises an instrumentation block which draws power from the host socket to power its operation. The instrumentation block further processes signals and conveys this information to the host device up on connecting the device jack to the host socket. The host device controls certain aspects of the electronics module for acquiring and processing plurality of signals. The instrumentation block in the device connects to one or more sensors through cables to sense at least one of electrocardiogram (ECG), Electroencephalography (EEG), motion, airflow of respiratory system, body temperature, light intensity of arterial oxygen saturation level, blood pressure and any other physiology signal.

Abstract: An algorithm for removing motion artifacts from the PPG signal in the time domain to determine heart rate is disclosed. A device for determining a heart rate of a user can include a heart rate sensor configured to generate heart rate signals when positioned on or adjacent to a user's skin, an accelerometer configured to generate one or more acceleration signals, and processing circuitry configured to remove, in a time domain, motion artifacts from the heart rate signals based on the acceleration signals. In some examples, the removal of motion artifacts can also be based on mean-centered, variance-scaled integrated acceleration signals. In some examples, the processing circuitry can be configured to remove motion artifacts using a least squares algorithm to identify a best representation of acceleration and integrated acceleration signals in the heart rate signals.

Abstract: A sensor that is capable of detecting a pulse of a user by using a proximity illumination sensor or a proximity sensor is provided. A proximity sensor (14) that includes a pulse detection function includes a count adjustment circuit (5) that performs adjustment such that a digital output value (ADCOUT1) from an analog-digital conversion circuit (4) changes in accordance with each value of a distance at least in a prescribed range of the distance between a photodiode (2) and a detected object (a finger in the drawing) and a digital filter (6) for detecting a cycle of the digital output value (ADCOUT1) from the analog-digital conversion circuit (4).

Abstract: Methods and apparatus for measuring pressure in a patient are provided which may include any number of features. One feature is a pressure measurement system comprising a pressure source, a compliant bladder, a catheter in communication with the pressure source, pressure sensors, and a controller configured to determine a pressure within the compliant bladder. The pressure measurement system can inflate the compliant bladder with gas or air to determine a pressure within a patient. In one embodiment, the pressure measurement system measures pressure within a peritoneal cavity.

Abstract: Microelectromechanical system are disclosed that include at least one electrode, microelectrode or combination thereof, wherein the at least one electrode comprises a carbon material, a glassy carbon material or a combination thereof. Contemplated systems are suitable for ?-ECoG arrays. Additional microelectromechanical systems are disclosed that include at least one electrode, microelectrode or combination thereof, wherein the at least one electrode comprises a carbon material, a glassy carbon material or a combination thereof; at least one substrate, surface, layer or a combination thereof, wherein the at least one electrode, microelectrode or combination thereof is disposed on, coupled with or otherwise layered on the at least one substrate, surface, layer or a combination thereof; and at least one bump pad, wherein the at least one electrode, microelectrode or combination thereof is coupled with the at least one bump pad via at least one conductive metal.

Abstract: The disclosure relates generally to applications of Orientation Independent Sensing (OIS) and Omnipolar mapping Technology (OT) to various system, device and method embodiments as recited herein. Similarly, systems and methods suitable for supporting OIS and OT systems and methods are disclosed. Further, OIS and OT implementations that provide end user interfaces, diagnostic indicia and visual displays generated, in part, based on measured data or derived from measured data are also disclosed. Embodiments also describe applying optimization techniques to determine the greatest voltage difference of a local electric field associated with an electrode-based diagnostic procedure and a vector representation thereof. Various graphic user interface related features are also described to facilitate orientation and electrode clique signal display.

Abstract: Implantable medical device systems and methods configured to use a detection profile selected from among a plurality of detection profiles to define a detection threshold for identifying cardiac events, in which a close call definition is used to determine which of the plurality of detection profiles is to be chosen. Upon identifying a close call, in which an overdetection nearly occurred but did not actually take place, a relatively less sensitive detection profile is chosen.

Abstract: A method for computerizing delineation and/or multi-label classification of an ECG signal, includes: applying a neural network to the ECG whereby labelling the ECG, and optionally displaying the labels according to time, optionally with the ECG signal.

Abstract: An arrangement may include a first system provided for processing physiological data representative of a beating heart. The first system may be adapted to execute a process for using at least one pattern to detect a notable finding in the physiological data and for sending the notable finding to a second system. The second system may be adapted to execute a process for analyzing the notable finding, for determining at least one new pattern to send to the first system, and for sending the at least one new pattern to the first system. The at least one new pattern may also include a rule that includes a set of conditions and an action to perform if the set of conditions is met.

Abstract: A method for characterizing an electrocardiogram, including receiving a first unipolar signal from a first location of a heart and a second unipolar signal from a second location of the heart. The method further includes generating a bipolar signal from the first and second unipolar signals, and analyzing the bipolar signal to delineate a time period during which the first and second locations generate a bipolar complex. The method also includes analyzing the first unipolar signal within the time period to determine an activation time of the first location.

Abstract: A device and method is described for electronic human prosthetics, and specifically a body-machine interface (BMI) device where the input, output and on-board computing are combined into a single unit to form a compact ECG, respiratory sensing, temperature-sensing-prosthetics device. The devices (BMIs) can also communicate with other body-machine interface devices (BMI) and/or with external controllers wirelessly. The compact device has ultrasonic battery charging system. One or more BMI can be wirelessly connected so that a closed loop of BMIs, or a BMI and an external controller, can wirelessly send trigger pulses to the stimulator over the heart, glossopharyngeal nerve(s) or diaphragm.

Abstract: Embodiments disclose a blood pressure parameter detection method. The method includes: detecting, by user equipment UE, an electrocardiogram ECG signal of a user by using a first ECG contact and a second ECG contact that are connected to an ECG detection circuit of the UE; when determining that the detected ECG signal matches a pre-stored reference ECG signal, enabling, by the UE, a photoplethysmogram PPG detection circuit, and detecting a PPG signal of the user by using a PPG detection point connected to the PPG detection circuit; and when determining that the detected PPG signal matches a pre-stored reference PPG signal, enabling, by the UE, a blood pressure detection application, and processing the detected ECG signal and the detected PPG signal by using the blood pressure detection application to obtain a blood pressure parameter of the user.

Abstract: An electrode for cardiac signal sensing includes an intermediate layer, an iridium-containing layer, an iridium oxide layer, an insulating polymer layer, and a conductive layer formed on a flexible polymer substrate. The intermediate metal layer has a first portion and a second portion, and is formed on the conductive layer. The iridium-containing layer includes at least 50 wt. % iridium and has a first portion and a second portion, and is formed on the first portion of the intermediate metal layer. The iridium oxide layer is formed on the first portion of the iridium-containing layer. The insulating polymer layer is formed on the second portion of the intermediate metal layer and the second portion of the iridium-containing layer. The iridium-containing layer is not formed on the second portion of the intermediate metal layer; and the iridium oxide layer is not formed on the second portion of the iridium-containing layer.

Abstract: It relates to the field of displaying the heart-rate data collected in an exercise test, in particular to a method for achieving a panoramic display during Electrocardiogram Exercise Test by using a time axis, comprising following steps: (a) building a horizontal axis (X axis) in units of time as a time axis, and building a vertical axis (Y axis) in units of heart rate, therefore forming a two-dimensional tendency chart; (b) collecting and storing real-time 12-lead ECG raw data, acquiring and storing real-time heart rate data, (c) setting a time vernier, wherein in a default status, the time vernier is located at the current moment, and it is connected with 12-lead ECG raw data.

Abstract: A system for monitoring a fetal heartbeat sound has a sensor matrix adapted to be placed adjacent to a fetus, a processor for receiving signals transmitted by the sensor matrix, a processor for receiving signals transmitted by the sensor matrix, and a display connected to the processor so as to provide a humanly perceivable indication of the heartbeat sound. The sensor matrix has a plurality of sensors of which at least one of which is facing the fetus. The processor identifies a fetal heartbeat sound from among other sounds. The sensor array is affixed to a wearable article that is adapted to be worn by mother.

Abstract: Cardiac activity can be mapped by receiving an electrogram, transforming the electrogram into the wavelet domain (e.g., using a continuous wavelet transformation) to create a scalogram of the electrogram, computing at least one energy function of the scalogram, and computing at least one metric of the electrogram using the at least one energy function. The metrics of the electrogram can include, without limitation: a QRS activity duration for the electrogram; a near-field component duration for the electrogram; a far-field component duration for the electrogram; a number of multiple components for the electrogram; a slope of a sharpest component of the electrogram; a scalogram width; an energy ratio in the electrogram; and a cycle-length based metric of the electrogram.

Abstract: An electrode cap contains at least one electrode array and is to be applied to a subject's head. The electrode array contains an insulating layer, two electrodes disposed opposite one another on the insulating layer, namely a first measurement electrode facing toward the subject's head and a reference electrode facing away from the subject's head. A conductive body abuts the reference electrode and is in electrical contact therewith, and is arranged on the side of the reference electrode that faces away from the subject's head. The individual conductive bodies of all the electrode arrays are electrically connected to each other.

Abstract: The present invention relates to a neurofeedback system that comprises an electrode (2, 2?, 2?) for contacting skin (6) of a user (7) for measuring a biofeedback signal (9) of the user (7), a first signal processing unit (3) for determining a signal characteristic (11) of the measured biofeedback signal (9), wherein the signal characteristic (11) represents a neurofeedback, a second signal processing unit (4) for determining a biofeedback signal quality (12) of the measured biofeedback signal (9) by extracting a signal feature of the measured biofeedback signal (9) and calculating a probability of a measurement error for said signal feature, which probability represents the biofeedback signal quality (12), and a feedback unit (5) for providing feedback to the user, wherein the feedback comprises the neurofeedback and a feedback about the biofeedback signal quality (12).

Abstract: A wearable monitoring apparatus for monitoring at least one biological parameter of an internal tissue of an ambulatory user. Said wearable monitoring apparatus comprises at least one transducer configured for delivering electromagnetic (EM) radiation to said internal tissue and intercepting a reflection of said EM radiation said reform in a plurality of transmission sessions during at least 24 hours, a processing unit configured for analyzing respective said reflection and identifying a change in said at least one biological parameter accordingly, a reporting unit configured for generating a report according to said change, and a housing for containing said at least one transducer, said reporting unit, and said processing unit, said housing being configured for being disposed on said body of said ambulatory user.

Abstract: One embodiment of the present application sets forth a method for detecting cancerous cells in a sample of excised tissue. The method includes a first subset of electrodes included in an electrode array measuring, at a first operating frequency, a first impedance of a first section of the sample. The method also includes computing a first Cole relaxation frequency for the first section of the sample based on the first impedance. The method also includes determining that the first section of the sample contains cancerous cells based on the first Cole relaxation frequency.

Abstract: A method and apparatus for compensating and calibrating a bio-impedance measurement device are provided. In the method and apparatus, a memory stores a plurality of compensation parameters and a first detection channel receives a first detection signal, compensates the first detection signal using a first compensation parameter of the plurality of compensation parameters. In the method and apparatus, a second detection channel receives a second detection signal and a third detection signal and compensates the second and third detection signals using second and third compensation parameters of the plurality of compensation parameters and the compensated first detection signal. The impedance measurement device generates a first output signal representative of a first impedance measurement and a second output signal representative of a second impedance measurement based on the compensated first, second and third detection signals.

Abstract: Embodiments of the present invention provide devices (tags with sensors), systems, and methods to determine states (such as, but not limited to, complex impedance) of materials-of-interest, such as tissue-of-interest, implants, and construction members, to name a few, in a non-invasive and contactless way; and using comparatively safe and/or low energy electromagnetic radiation, such as radio waves. Negligible-sized wireless-tags with sensors are implanted in such materials-of-interest. Using wireless communication and imaging technology, the states of the materials-of-interest may be monitored; which may allow non-invasive and contactless detection of problems such as cracking, bending, excessive pressure, improper temperature, and/or the like. Additionally, initially unknown locations of the implanted negligible-sized wireless-tags with sensors may be readily determined upon a given scanning (reading) session; and thus mapped to provide an effective image of the material-of-interest.

Abstract: A method operates an image system of a medical imaging modality in which a patient data record of a patient is processed. A workflow for an examination is selected from a set of workflows on the basis of an examination specification of the patient data record. Wherein each workflow contains comprises a selection from a set of functions which are carried out in a specific temporal sequence.

Abstract: A method of obtaining information about the position and/or orientation of a magnetic component relatively to a magnetometric detector, the magnetic component and the magnetometric detector being moveable independently from each other relatively to a static secondary magnetic field, the method comprising the steps of: measuring in the presence of the combination of both the magnetic field of the magnetic component and the static secondary magnetic field essentially simultaneously the strength and/or orientation of a magnetic field at at least a first position and a second position spatially associated with the magnetometric detector, the second position being distanced from the first position; and combining the results of the measurements to computationally eliminate the effect of the secondary magnetic field and derive the information about the position and/or orientation of the magnetic component.

Abstract: An improved device for monitoring respiration or other vital signs of a user using one or more sensors. The invention may be worn within the mouth of the user to allow more accurate, direct, and fast measurements. The invention may also include a distribution mechanism that may be used to administer a substance such as medication. The substance may be administered in response to data collected by one or more of the sensors in the device and/or in response to data received from another device.

Abstract: This disclosure relates to a system configured to detect the presence of secretions in a subject's airway during respiratory therapy. The system can determine whether the subject requires airway clearance. A pressure generator generates a pressurized flow of breathable gas. Sensors generate output signals relating to one or more gas parameters of the pressurized flow of breathable gas. The system can determine a first parameter that is an indication of the volume of breathable gas within the airway of the subject and a time derivative of the first gas parameter to generate a plot of these parameters. The plot includes a perimeter and an area that can be used to determine whether to effectuate initiation of airway clearance based on a complete breathing cycle that includes at least one inhalation and exhalation.

Abstract: Disclosed are a system and a method for rehabilitation exercise of hands. The system and the method help a device sense movements of the hands more accurately. The device for rehabilitation exercise of the hands comprising multiple sense parts that are located on each part of a user's hand, and configured to sense movements of the each part; and communication part configured to send movement data sensed by the multiple sense parts to an output device.

Abstract: A mobile computing device for measuring somatic response of a user to stimulus includes motion sensors, a volatile memory, and a processor for: executing a baseline calibration process including receiving first and second supervised data from the user, and first and second sensor data from the motion sensors, while the user performs a triple whip gesture, calculating signal strength of the first and second sensor data using a k-means clustering algorithm, and executing a classification process including reading third unsupervised data from the user and third sensor data from the motion sensors while the user performs the triple whip gesture.

Abstract: Disclosed embodiments describe techniques for body part motion analysis. A stretch sensor is attached to a body part. Tape can be applied to the body part, and the stretch sensor can be attached to the tape using connectors, hooks, snaps, or Velcro™. The stretch sensor changes electrical characteristics as it stretches. A sensor coupled to the stretch sensor collects changes in electrical characteristics based on motion of the body part. A communication unit provides information from the sensor to a receiving unit. Motion of the body part is shown on a display. The displayed body part can be an animation and can be displayed in the context of an overall body. The stretch sensor is used for measuring body part motion. An inertial measurement unit provides augmented motion information. The stretch sensor senses muscle activities such as muscle activation and deformation and provides movement angle, force and torque evaluation.

Abstract: Provided herein are patient mobility assessment devices having a mobility assistance device with an incorporated distance tracker for use in assessing the ambulation of a recovering medical patient. The distance tracker can be integrated into or removably attached to the mobility assistance device. The information obtained may be displayed on the mobility assistance device and/or at a nurse's station or other remote location for convenient monitoring of patient ambulation. Also provided herein are methods for evaluating patient ambulation using the mobility assessment device and optionally, provision of therapeutic ambulation protocols to a display on the device to assist with patient physical therapy and recovery.

Abstract: A system for monitoring a person may include a person-worn sensor device including at least one sensor (e.g., at least one accelerometer, magnetometer, altimeter, etc.) configured to collect sensor data and a processor to process data from the person-worn sensor device. The processor may be configured to determine or access an orientation of a physical support apparatus (e.g., bed, table, wheelchair, chair, sofa, or other structure for supporting the person), receive sensor data collected by the person-worn sensor device, calculate an orientation of the person relative to the physical support apparatus based on (a) the orientation of the physical support apparatus and (b) the sensor data collected by the person-worn sensor device, and identify, based on the determined orientation of the person relative to the physical support apparatus, a physical support apparatus exit condition indicating an occurrence or anticipated occurrence of the person exiting the physical support apparatus.

Abstract: The invention relates to an assistance device intended for a person (1) suffering from motor disorders of neurological origin, comprising: an accelerometer suitable for being worn by the person to measure accelerations; and storage means storing a plurality of previously defined alert acceleration threshold values; and means (5) for emitting an auditory stimulation perceptible to the person wearing the accelerometer; and calculation means configured to perform the following steps: a) determine a posture of the person from the measured accelerations; b) compare the accelerations measured by said accelerometer in the first direction in relation to at least one anticipatory acceleration threshold value associated with said posture; c) command the emission of an auditory stimulation as a function of the crossing of said anticipatory acceleration threshold value associated with said posture for a determined time associated with said anticipatory acceleration threshold value.

Abstract: A processing apparatus (6) for determining a respiration signal (34) of a subject (100) is presented. The processing apparatus (6) is configured to perform the steps of obtaining a movement signal (22) descriptive of a respiratory movement, determining a first quantity (24) descriptive of a rotation axis and/or rotation angle based on the obtained movement signal (22), and estimating a rotation axis (25) and/or rotation angle (26) based on the first quantity (24) and a rotation model, wherein the rotation model models the respiratory movement as a rotation around a single rotation axis. This model of the rotation can be further used as a feature for an instantaneous classifier descriptive of a movement artifact descriptive of a non-respiratory movement. Furthermore, a processing method, a respiration monitor (1, 91), a computer-readable non-transitory storage medium and a computer program are presented.

Abstract: Described and disclosed herein are various embodiments of systems, devices, components and methods configured to employ acoustic coordinated reset neuromodulation therapies that are capable of adjusting or modulating at least one of the intensity, auditory filter bandwidth, and center frequency of therapeutic stimulation signals delivered to an individual patient, where in one embodiment such signals are tuned to have intensities that are above or slightly above the individual patient's hearing threshold.