Abstract: A method for determining an interaction between a first protein and a second protein comprises the steps of: expressing in a cell or introducing into a cell a first fusion protein comprising the first protein, a multimerizable protein, and a fluorescent protein, and a second fusion protein comprising the second protein and a multimerizable protein; detecting a fluorescent focus formed by an association between the first fusion protein and the second fusion protein in the cell; and determining an interaction between the first protein and the second protein according to the detection of the fluorescent focus.

Abstract: The present invention relates provides methods of predicting cell sensitivity to a test agent. In some embodiments, the cells are cultured in a culture medium having serum.

Abstract: The existent therapeutic drugs for CNV are merely pharmaceuticals for a symptomatic therapy, and therapeutic drugs for radical cure are strongly demanded. Also, a therapeutic drug for Dry AMD does not exist, and therapeutic drugs for radical cure are strongly demanded. The present invention provides a prophylactic and/or therapeutic agent for choroidal neovascularization, containing a compound having an activity of suppressing epithelial-mesenchymal transition in retinal pigment epithelial cells, as an active ingredient. Also, the present invention provides a drusen suppressor comprising a compound having an activity of suppressing epithelial-mesenchymal transition in retinal pigment epithelial cells, as an active ingredient.

Abstract: Although limited proteolysis of the histone H3 N-terminal tail (H3NT) is frequently observed during mammalian differentiation, the specific genomic sites targeted for H3NT proteolysis and the functional significance of H3NT cleavage remain largely unknown. Here Applicant reports the first method to identify and examine H3NT-cleaved regions in mammals, called ChIP of acetylated chromatin (ChIPac). By applying ChIPac-Seq to an established cell model of osteoclast differentiation, Applicant discovered that H3NT proteolysis is selectively targeted near transcription start sites of a small group of genes and that most H3NT-cleaved genes displayed significant expression changes during osteoclastogenesis. Applicant also discovered that the principal H3NT protease of osteoclastogenesis is matrix metalloproteinase 9 (MMP-9). In contrast to other known H3NT proteases, MMP-9 primarily cleaved H3K18-Q19 in vitro and in cells.

Abstract: Techniques for selective placement of carbon nanotubes using bifunctional acid monolayers are provided. In one aspect, a method for selective placement of carbon nanotubes on a metal oxide surface includes the steps of: dispersing poly-fluorene polymer-wrapped carbon nanotubes in an organic solvent; creating a patterned monolayer of a bifunctional acid on the metal oxide surface, wherein the bifunctional acid comprises a first acid functional group for binding to the metal oxide surface, and a second acid functional group for binding to the poly-fluorene polymer-wrapped carbon nanotubes; and contacting the poly-fluorene polymer-wrapped carbon nanotubes dispersed in the organic solvent with the patterned monolayer of the bifunctional acid on the metal oxide surface to selectively place the carbon nanotubes on the metal oxide surface via the patterned monolayer of the bifunctional acid. A carbon nanotube-based device and method of formation thereof are also provided.

Abstract: The invention generally relates to performing sandwich assays in droplets. In certain embodiments, the invention provides methods for detecting a target analyte that involve forming a compartmentalized portion of fluid including a portion of a sample suspected of containing a target analyte and a sample identifier, a first binding agent having a target identifier, and a second binding agent specific to the target analyte under conditions that produce a complex of the first and second binding agents with the target analyte, separating the complexes, and detecting the complexes, thereby detecting the target analyte.

Abstract: Herein is reported an enzyme linked immunosorbent assay for the detection of anti-drug antibodies against a drug antibody in a sample comprising a capture drug antibody and a tracer drug antibody, wherein the capture drug antibody and the tracer drug antibody are employed in a concentration of 0.5 ?g/ml or more, the sample is incubated simultaneously with the capture drug antibody and the tracer drug antibody for 1 to 24 hours, the capture drug antibody and the tracer drug antibody are derivatized via a single lysine residue, the sample comprises 10% serum, and oligomeric human IgG is added to the sample prior to the incubation with the capture drug antibody and the tracer drug antibody.

Abstract: Provided is a multi-flux micro-fluidic chip including a chip body. The chip body includes a fluid inflow cavity communicated with an external air path, reaction-quantification cavities, waste liquid cavities, and a fluid path distribution cavity disposed at a middle position of the chip body. The two or more reaction-quantification cavities are distributed on two sides of the fluid path distribution cavity in rows to form the first and second row of reaction-quantification cavities respectively; and they are communicated with a fluid outlet of the fluid path distribution cavity through fluid path branches, and a fluid inlet of the fluid path distribution cavity through fluid path branches, and a fluid inlet of the fluid path distribution cavity is communicated with a fluid outlet of the fluid inflow cavity and an external fluid path, which making it possible to detect multiple items simultaneously and greatly improving the flux of the micro-fluidic chip.

Abstract: Disclosed is a system and method for a microdevice to separate blood cells based on differences in antigen expression. Specifically, cells of the same phenotype are separated based on whether or not they are activated during infection or resting. The device of the present disclosure takes a small sample of blood and provides differential cell counts that can be used to test for infection and inflammatory response. The device can be used to identify sepsis and other infections rapidly. By measuring differences in activated white cell counts such as neutrophils, the device of the present disclosure measures physiological response to infection in hospitalized patients recovering from burns, surgeries, etc.

Abstract: The present invention provides self-contained systems for performing an assay for determining a chemical state, the system including a stationary cartridge for performing the assay therein, at least one reagent adapted to react with a sample; and at least one reporter functionality adapted to report a reaction of the at least one reagent with said sample to report a result of the assay, wherein the at least one reagent, the sample and the at least one reporter functionality are contained within the cartridge.

Abstract: A microfluidic device including a serum separator, a quantum dot and antibody inlet connected to the serum separator, a quantum dot linked immunosorbent assay (QLISA) chamber connected to the serum separator, and an outlet connected to the QLISA chamber. The microfluidic device is configured to determine an amount of drug in a serum.

Abstract: Peptide and/or protein quantitation methods, kits, and compositions, particularly useful for mass spectrometry, are provided herein based on a bathocuproine-based composition complex such as bathocuproinedisulfonic acid disodium salt hydrate complex. The methods are one-step rapid absorbance methods using small sample volumes. They produce a robust signal with high signal to background ratio and accurately quantitate even complex peptide mixtures with low variability and high sensitivity.

Abstract: Herein is reported a method for the detection of free antigen of a multispecific antibody in a sample, whereby the antigen to be detected can be specifically bound by a first binding site of the multispecific antibody, comprising the step of incubating a sample comprising free antigen and multispecific antibody with an anti-idiotypic antibody, which specifically binds to a second binding specificity of the bispecific antibody, which is different from the first binding specificity, whereby the anti-idiotypic antibody is bound to a solid phase.

Abstract: The present invention relates to methods and tools for discriminating between Vel negative and Vel positive phenotypes. The invention is thus useful for determining Vel blood group status of individuals about to receive blood transfusion.

Abstract: Disclosed herein are methods for detecting protein expression in an individual diagnosed with cystic fibrosis. The methods, in certain aspects, include the steps of obtaining a sample from said individual and detecting expression in said sample of each protein of a protein set. The method may further include the step of determining expression level of one or more proteins of the protein set. The disclosed methods may be used to predict one or more clinical parameters in an individual having cystic fibrosis.

Abstract: A method of determining risk factors for Alzheimer's disease in an individual, including assaying a biological medium obtained from the individual for a biomarker selected from Biomarker 1, Biomarker 2, Biomarker 3, or Biomarker 4, where Biomarker 1 has a mass-to-charge ratio (m/z) of 602.3, Biomarker 2 has a m/z of 804.6, Biomarker 3 has a m/z of 874.6, and Biomarker 4 has a m/z of 804.5, and where the presence of the two or more biomarkers in the individual indicates a risk factor of Alzheimer's disease.

Abstract: A test apparatus and method for measuring a concentration of a target by correcting for an impact of hemoglobin are provided. The target measurement method includes measuring an absorbance of hemoglobin in a sample, measuring an absorbance of a target in the sample, determining variation of the absorbance of the target according to the measured absorbance of the hemoglobin, and correcting the absorbance of the target by subtracting the determined variation of the absorbance of the target from the measured absorbance of the target.

Abstract: Provided is a method for derivatizing an s-cis-diene compound with a Cookson-type derivatization reagent, the method including adding, in a reaction stopping step of stopping a derivatization reaction of the s-cis-diene compound, a decomposition inhibitor to inhibit decomposition of a derivative to be obtained.

Abstract: The present invention provides a method for diagnosing in a subject Acute Kidney Injury or a related or analogous disease state. The method comprises the steps of a) providing a sample taken from the subject: b) analysing the sample from the subject to determine the level of a biomarker selected from certain atomic species; and c) comparing the level of the biomarker in the sample to a reference level of the biomarker that is characteristic of a healthy subject, eg a subject having normal renal function. An elevated level of the biomarker in the sample relative to the reference level is indicative of Acute Kidney Injury or a related or analogous disease state. The invention also relates to the use of an atomic species selected from those in Table 1 as a biomarker for Acute Kidney Injury or a related or analogous disease state, and test kits comprising an analytical element sensitive to those biomarkers.

Abstract: One or more liquids are transferred from a source array to one or more remotely positioned destination sites such as chambers by utilizing one or more movable transfer elements, such as contact pins or capillaries. The source array may include a predetermined organization of addresses at which materials are positioned. One or more materials may be selected for transfer. Based on the selection, one or more addresses may be accessed by the transfer element(s). The addresses may correspond to spots on a surface of the source array. Each spot may be a feature containing one or more (bio)chemical compounds. At the chamber(s), the material(s) may be processed, such by reaction with one or more reagents. The reaction(s) may entail synthesis of one or more desired products. Alternatively, reaction(s) may be performed at the source array, and the product(s) then transferred to the chamber(s).

Abstract: An automatic analyzing apparatus is provided which includes a member 401 fixed at a predetermined level which presses down the sample container sealed with the sealing plug that is floated from the rack due to friction between the probe and the sealing plug when pulling out the probe from the sample container sealed with the sealing plug, and a mechanism 402 that pushes down, toward the rack, the sample container sealed with the floated sealing plug in which the sample container sealed with the floated sealing plug is transported by the transport line, and disposed on a path of the transport line until re-inspection is performed after pulling out the probe from the sample container sealed with the sealing plug.

Abstract: A speed detection device includes a comparator module, a sensor lead with a node connected to the comparator module, and a limit set module. The limit set module is connected to the sensor lead node and to the comparator by an upper limit lead and a lower limit lead to provide upper and lower limits to the comparator that vary according to amplitude variation in voltage applied to the sensor lead.

Abstract: Disclosed is apparatus and a method for detecting udder disease in dairy animals. An accelerometer is attached to each of a plurality of dairy animals. A processor determines a measure of the activity of the dairy animals to which the accelerometers are attached. Data is recorded by and automatically transmitted from a sensor unit secured to an animal, without the requirement for costly and time consuming chemical analysis of milk, or of visual or veterinary inspection of individual animals in a herd. The development of an udder disease in a dairy animal, such as mastitis, may be identified from a decrease in the monitored measure of activity of a dairy animal. A separate baseline measure of activity may be determined for each dairy animal and the activity of a plurality of dairy animals in one or more herds may be taken into account, in order to reduce false positives due to external effects which are not specific to a single dairy animal.

Abstract: A microelectromechanical system (MEMS) apparatus is described. The MEMS apparatus may comprise inertial sensors and energy harvesters configured to convert mechanical vibrational energy into electric energy. The harvested energy may be used to power an electronic circuit, such as the circuit used to sense acceleration from the inertial sensors. The inertial sensors and the energy harvesters may be disposed on the same substrate, and may share the same proof mass. The energy harvesters may include a piezoelectric material layers disposed on a flexible structure. When the flexible structures flexes in response to vibration, stress arises in the piezoelectric material layer, which leads to the generation of electricity. Examples of inertial sensors include accelerometers and gyroscopes.

Abstract: A physical quantity sensor includes a substrate, an element portion disposed so as to overlap the substrate, a conductor pattern disposed on the substrate so as to face the element portion, and a protection film covering at least a part of an exposed portion of the conductor pattern exposed from element portion in a plan view from a direction in which the substrate and the element portion overlap.

Abstract: Disclosed is related generally to a contact for testing a semiconductor device and a socket device therefor. The contact of the present invention, being a spring contact configured in an integrated body by blanking and bending a metal board, includes: an elastic part composed of various strips in a fixed pattern, and sharp end parts provided on opposite ends of the elastic part, respectively. Preferably, with a filler having conductivity and elasticity being filled in space volume, the contact of the present invention has excellent durability and electrical characteristics. In addition, the test socket according to the present invention, being the rubber type adopting the above-stated contacts, provides an appropriate effect for a test of a semiconductor device having a fine pitch.

Abstract: A system includes a controller for automated test equipment (ATE) contactor to interface with a device under test (DUT) including a power converter having a primary and secondary side, each side has an input/output (I/O) pin. The controller causes the ATE contactor to apply a load current on the secondary side of the power converter at a first value and vary the load current to a second value. The contactor receives first and second indications, at the first and second load currents, of a voltage on the primary side I/O pin, a voltage on the primary side of the power converter, an input current on the primary side of the power converter, a voltage on the secondary side I/O pin, and a voltage on the secondary side of the power converter. The controller determines a primary and secondary side ATE contactor resistances based on the first and second indications.

Abstract: A high density thin walled test device testing chips/ICs is disclosed. A housing includes a slot for a contact pin and a pair of elastomers. The pin has an arcuate recess to receive part of the elastomer. Likewise the housing includes a channel to receive part of the elastomer. The recess and channel together partially surround the elastomer but not completely to allow shear forces and expansion space for the elastomer as it is compressed by the channel and recess. In addition, a front channel extends from the top surface of the housing toward the bottom surface but leaving a floor to support the elastomer so that it does not warp the housing when compressed. Further, the channel or the recess may include retainers which prevent the elastomer from moving out of position when the pin is in an uncompressed state.

Abstract: A probe card for a testing apparatus of electronic devices comprises at least one testing head housing a plurality of contact probes, each contact probe having at least one contact tip abutting onto contact pads of a device under test, as well as at least one space transformer realizing a spatial transformation of the distances between contact pads made on its opposite sides and connected by means of suitable conductive tracks or planes, as well as a plurality of filtering capacitors provided between the space transformer and a PCB, which comprises direct conductive tracks or planes contacting conductive portions of the filtering capacitors.

Abstract: A main feed thru unit configured as a service equipment or a main service disconnect is provided for distributing power in modular metering mains. The main feed thru unit comprises an enclosure having a back side, a first side, a second side, a top side and a bottom side and a bus assembly. The bus assembly includes a feed thru bus assembly including a plurality of feed thru bus bars configured to receive line power at feed line terminals and pass thru power to feed thru terminals, a cross bus assembly including a plurality of cross bus bars extending between the first side and the second side and a main breaker coupled between the feed line terminals and the plurality of cross bus bars to feed power thru and output power via the plurality of cross bus bars. The enclosure is configured to allow electrical connection to the plurality of cross bus bars through an opening in at least one of the first side and the second side.

Abstract: A sensor detects a detected value for a covered wire without metallic contact, and includes: a tubular support that has a male thread and an insertion channel in which the covered wire is inserted and supported; a tubular shell that is inserted into the support from a base end; a pillar-shaped detection electrode that is inserted in and supported by the shell; and a tubular threaded piece that screws onto the male thread, is rotatably attached onto the shell, and is moved, along the axis of the support, together with the shell and the detection electrode by a screwing operation. The detection electrode is configured so that the front surface is pressed onto the covered wire in the support when the detection electrode moves, resulting in the front surface becoming capacitively coupled to a core wire of the covered wire via an insulating covering.

Abstract: Sensors measure magnetic field components, and the measured fields are used to calculate and estimated transverse position of a longitudinal electric current flowing as an electric discharge across a discharge gap. Based on the estimated position, and according to a selected transverse trajectory or distribution of the estimated discharge position, magnetic fields are applied transversely across the discharge gap so as to control or alter the estimated discharge position. Inventive apparatus and methods can be employed, inter alia, during operation of a vacuum arc furnace.

Abstract: A voltage sensor comprises a conductor (102) having a first end (101) and a second end (103), the first end including a first connection interface (150) and the second end having no connection, and a sensor section (125) including at least one sensor disposed over the conductor, the sensor sensing the sensor sensing at least a voltage or a sample of the voltage of the conductor. The voltage sensor is coupleable to a power line or cable, such as an overhead power line or cable, or a cable accessory, and can also be used in underground applications.

Abstract: The present disclosure provides a battery high voltage sampling circuit and a battery management system. The battery high voltage sampling circuit includes a positive relay, a negative relay, a first positive sampling unit, a first negative sampling unit and a reference voltage terminal, wherein: a first terminal of the positive relay is connected to a positive electrode of a power battery pack to be detected, a first terminal of the negative relay is connected to a negative electrode of the power battery pack to be detected, and both of the first positive sampling unit and the first negative sampling unit are connected to the reference voltage terminal.

Abstract: Implementations of voltage sensing systems may include: a high side current mirror coupled to a reference current source coupled to at least one diode. The at least one diode may be coupled to a resistor and to a comparator. The resistor may be coupled to the ground. The comparator may be coupled with a reference voltage. The comparator may be configured to receive a comparison voltage from the diode and output whether the comparison voltage is higher or lower than the reference voltage.

Abstract: Systems and methods are described herein for reducing the effects of magnetic field cross-coupling in a multi-conductor current sensor system. A current sensor system includes one or more current sensors, each positioned proximate to at least one conductor and spaced from at least one other conductor. Each conductor carries a current intended to be measured by a respective current sensor. The current sensors include one or more magnetic field sensing elements to generate a magnetic field signal indicative of a detected magnetic field. A characterization measurement is performed to determine the coupling between each current sensor and the respective current conductor and to determine the coupling between the current sensor and the other ones of the current conductors, by providing a reference current to each of the conductors and measuring the outputs at each of the current sensors. The characterization measurement can be used to generate a coupling matrix.

Abstract: In various embodiments, a method for processing a Single-Edge Nibble Transmission Signal is provided. The method includes determining of at least one drop in a signal level of the time-variable Single-Edge Nibble Transmission Signal and at least one next rise in the signal level after the drop in the signal level, determining a time interval between the drop and the next rise in the signal level, and determining a quality of the Single-Edge Nibble Transmission Signal by using the time interval.

Abstract: A method is provided. The method comprises determining configuration data; wherein the configuration data comprises a resistance of a bypass circuit coupled between a remote radio head and a power cable; using the configuration data, determining the resistance of the power cable coupling a programmable power supply to the remote radio head mounted on a mounting structure, comprising: entering a calibration mode; setting an output voltage of the programmable power supply; measuring an output current of the programmable power supply; storing the output current; and determining the cable resistance; and storing the resistance of the power cable.

Abstract: An apparatus and a method for use in an electric circuit. The apparatus includes a sampling module arranged to obtain an approximation of a voltage-current characteristic of at least one electrical circuit component of the electric circuit subjected to an excitation, wherein each of the at least one electrical circuit component is represented by a constant phase element in an equivalent circuit of the electric circuit; and a processing module arranged to estimate a time-domain voltage response and/or a time-domain current response based on the approximation of the voltage-current characteristic under the excitation applied to the electric circuit.

Abstract: An electronic device including a connector having a plurality of pins, and a detection circuit having at least one of a pull-up circuit and a pull-down circuit, and a connection circuit between a first pin and a second pin of the plurality of pins, the detection circuit is configured to select the first pin and the second pin, measure an impedance between the selected first pin and second pin by controlling a connection of the connection circuit and the at least one of the pull-up circuit and the pull-down circuit, and generate a detection signal indicating a presence or an absence of a foreign object on the connector based on the measured impedance.

Abstract: One embodiment includes and I/O bus including a signal line coupled to a signal source and multiple line switches, each line switch to couple a corresponding I/O port to the signal line. Switch logic coupled to the I/O bus may programmatically switch the multiple line switches to couple at least one of the signal source and measurement circuitry to the respective I/O port.

Abstract: Provided is an electro-optic probe for detecting an electromagnetic wave, including: an electro-optic crystal; and an optical fiber optically coupled to the electro-optic crystal, wherein a direction of a unique axis of the electro-optic crystal and a polarization direction of light from the optical fiber that enters the electro-optic crystal are set to be in line with each other, or wherein a direction of a unique axis of the electro-optic crystal and a unique polarization direction of the optical fiber are set to be in line with each other.

Abstract: A system and method of electronic component authentication or component classification can reduce the vulnerability of systems (e.g., satellites, weapons, critical infrastructure, aerospace, automotive, medical systems) to counterfeits. Intrinsic deterministically random property data can be obtained from a set of authentic electronic components, processed, and clustered to create a classifier that can distinguish whether an unknown electronic component is authentic or counterfeit.

Abstract: Methods and systems for inline parts average testing and latent reliability defect recognition or detection are disclosed. An inline parts average testing method may include: performing inline inspection and metrology on a plurality of wafers at a plurality of critical steps during wafer fabrication; aggregating inspection results obtained from inline inspection and metrology utilizing one or more processors to obtain a plurality of aggregated inspection results for the plurality of wafers; identifying one or more statistical outliers among the plurality of wafers at least partially based on the plurality of aggregated inspection results obtained for the plurality of wafers; and disqualifying the one or more statistical outliers from entering a supply chain for a downstream manufacturing process, or segregating the one or more statistical outliers for further evaluation, testing or repurposing.

Abstract: A method for monitoring, metering and improving system parameters, including leakage sensitivity and response over a time period in an electrical panel for a single phase system, or a 3-phase system comprising phase lines X, Y and Z, wherein the system reaction and accuracy are critical to a decision to disconnect the line with the malfunction before operation of the leakage breaker to cut off power. Set parameter 1: a leakage threshold in mA that can be changed in system setup mode. Set parameter 2: Allowable deviation in mA for alert; and set parameter 3: Maximum deviation in mA to disconnect currents. Set parameter N for the time to include in an average calculation.

Abstract: Disclosed herein are voltage driver circuits and methods of operating the same. In some embodiments, a plurality of circuit slices are provided in a voltage driver circuit, each circuit slice is controlled to switchably connect a driver output to either a high voltage level or a low voltage level via a resistor, or to disconnect the driver output from both voltage levels. The circuit slices may provide an adjustable output impedance, which may be set to match the impedance of different loads. The circuit slices may also provide adjustable voltages with low power consumption, particularly in high speed applications. A calibration procedure is disclosed herein to generate a lookup table for how to selectively connect circuit slices to supply voltages given a target output voltage.

Abstract: Methods and computer-readable media for testing integrated circuit designs implement a physically efficient scan by optimally balancing and connecting scan segments in a 2-dimensional compression chain architecture. A compression architecture that provides an optimal and balanced configuration of scan segments in 2D compression grids to not only decrease test time, but also to maximize compression efficiency and limit wiring congestion for IC designs that contain complex scan segments facilitates efficient scanning of data by bisecting the elements into balanced partitions of the same target scan length. A segment padding algorithm, followed by a bisecting algorithm and ultimately an element swapping algorithm may be applied to optimally balance and connect scan segments in 2-D compression chains, optimizing an efficient compression architecture which minimizes scan testing resources and time.

Abstract: A semiconductor device includes a first integrated chip; a second integrated chip; a plurality of reference through-chip vias formed through the first and second integrated circuit chips; and at least a normal through-chip via formed through the first and second integrated circuit chips, wherein the first integrated circuit chip comprises: a plurality of reference sourcing circuits suitable for sourcing a reference current to the respective reference through-chip vias; and at least a sourcing circuit suitable for sourcing the reference current to the normal through-chip via, and wherein the second integrated circuit chip comprises: a plurality of reference sinking circuits suitable for sinking currents flowing through the respective reference through-chip vias; a line suitable for electrically coupling the plurality of reference through-chip vias; a comparison voltage generation circuit suitable for generating a plurality of comparison voltages based on a voltage of the line; at least a sinking circuit suitab

Abstract: A crack detection system and an apparatus equipped with a crack detection circuit, including a main body, and a detection control circuit and a detection coil disposed on the main body. The main body includes a top surface, a bottom surface, and a side surface coupled between the top surface and the bottom surface. The detection coil is distributed on an edge of the main body and disposed surrounding the side surface. Two ends of the detection coil are electrically coupled to the detection control circuit to form a closed-loop detection circuit. The detection circuit is configured to detect a crack in an edge region of the main body. The detection coil includes a plurality of detection sections sequentially coupled from head-to-tail, and adjacent detection sections are not collinear.

Abstract: A method for identifying the noise figure of a device under test is described. A signal generator that outputs the modulated signal, a device under test and an analyzer are provided. The signal generator is connected with the analyzer directly wherein at least two error vector magnitude measurements are performed. The signal generator is connected with the device under test and the device under test is connected with the analyzer wherein at least two error vector magnitude measurements are performed. The noise contribution of the device under test is determined from the error vector magnitude measurements performed. A gain measurement is performed on the device under test. The noise figure of the device under test is calculated based on the noise contribution of the device under test obtained and the gain of the device under test obtained. Further, a measurement system is described.