Patents Issued in October 29, 2020
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Publication number: 20200339899Abstract: Provided is a method of preparing a combustible oil, the method comprising adding and mixing: a petroleum-based combustible oil; a water having an oxidation-reduction potential of ?300 mV or lower, a pH of 9.0 or higher, and a dissolved hydrogen concentration of 0.8 ppm or higher; a fatty oil; and an activated carbon to obtain a mixture.Type: ApplicationFiled: October 29, 2018Publication date: October 29, 2020Applicant: Fusion Group Holdings Co., Ltd.Inventors: Kenji Miyata, Kishio Arita
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Publication number: 20200339900Abstract: A hydrate formation promoter and the use thereof in methane storage. The hydrate formation promoter is a mixed aqueous solution including cyclopentane, sodium dodecyl sulfate and water, wherein a volume fraction of the cyclopentane is 5% to 23.4% and a mass fraction of the sodium dodecyl sulfate is 0.01% to 0.08%. The hydrate formation promoter can realize effective and rapid formation of methane hydrate at approximate room temperature (25° C.), and can remain stable at higher temperatures.Type: ApplicationFiled: March 26, 2019Publication date: October 29, 2020Applicant: GUANGZHOU INSTITUTE OF ENERGY CONVERSION, CHINESE ACADEMY OF SCIENCESInventors: Xiaosen LI, Yisong YU, Zhaoyang CHEN
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Publication number: 20200339901Abstract: The present disclosure relates to firearm lubricant compositions that serve to lubricate firearms and protect from rust and wear, and also contain a scent component that serves to mask the aversive smell of traditional firearm lubricant compositions.Type: ApplicationFiled: April 21, 2020Publication date: October 29, 2020Inventor: KIRK SHERBINE
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Publication number: 20200339902Abstract: Provided is a lubricating oil composition and methods for controlling one or more of foam tendency and foam stability in such composition using as the oil a mixture of at least two base stocks. The at least two base stocks have a surface tension difference between them such that, when the surface tension difference is greater than 1.0 dynes/cm, then one or more of foam tendency and foam stability are enhanced as compared to foam tendency and foam stability achieved using the base stocks separately and not in the mixture. When the surface tension difference between them is less than 1.0 dynes/cm, then one or more of foam tendency and foam stability are reduced or equivalent as compared to foam tendency and foam stability achieved using the base stocks separately and not in the mixture. Two low-foaming base stocks can produce a significant high foam response that reduces or eliminates the need for pro-foaming additives.Type: ApplicationFiled: April 17, 2020Publication date: October 29, 2020Inventors: Michael L. Blumenfeld, James T. Carey, Angela S. Galiano-Roth
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Publication number: 20200339903Abstract: The present invention relates to a lubricating oil composition containing a base oil (A) containing an olefin-based polymer (A1) having an area ratio of a peak derived from a hydride (A11) of a decene trimer of 80% or more relative to 100% of a total area of peaks derived from the olefin-based polymer (A1) detected in a chromatogram and having predetermined kinematic viscosity, flash point, and pour point, a viscosity index improver (B) containing a comb-shaped polymer (B1), and an organic molybdenum-based compound (C), in which the content of the comb-shaped polymer (B1) is regulated within a specified range and having a HTHS viscosity at each of 150° C. and 50° C. of the lubricating oil composition and a NOACK value in predetermined ranges, respectively.Type: ApplicationFiled: August 3, 2018Publication date: October 29, 2020Applicant: IDEMITSU KOSAN CO., LTD.Inventor: Hiroshi OKI
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Publication number: 20200339904Abstract: The lubricating oil composition includes a base oil and a fullerene adduct.Type: ApplicationFiled: October 24, 2018Publication date: October 29, 2020Applicant: SHOWA DENKO K.K.Inventors: Ryuji MONDEN, Yu GAO, Kunio KONDO, Masumi KURITANI
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Publication number: 20200339905Abstract: The invention relates to the field of lubricants and provides a lubricating composition comprising at least one base oil, the kinematic viscosity of which measured at 40° C. does not exceed 10 mm2/s and the pour point of which does not exceed ?50° C., and at least one thickener, said lubricating composition having a pour point not exceeding ?55° C.Type: ApplicationFiled: October 30, 2018Publication date: October 29, 2020Inventors: Nicolas CHAMPAGNE, Eric RAPIN
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Publication number: 20200339906Abstract: The invention discloses a photocured medical catheter hydrophilic lubricating coating and a preparation method thereof. The hydrophilic lubricating coating comprises a primer coating and a lubricating coating. The primer coating is attached to the surface of a device, and the lubricating coating is attached to the primer coating. The primer coating comprises 1-10 parts by weight of one or more polyester acrylates, 50-90 parts by weight of one or more solvents, 0.5-5 parts by weight of one or more photoinitiators, 0.5-2 parts by weight of one or more wetting agents and 0.5-5 parts by weight of one or more reactive (or active) diluents. The lubricating coating comprises 1-10 parts by weight of one or more water soluble macromolecules, 1-5 parts by weight of one or more crosslinking (or crosslinked) macromolecules, 0-1 part by weight of one or more photoinitiators, 0.1-1 part by weight of one or more surfactants and 50-98 parts by weight of one or more solvents.Type: ApplicationFiled: July 2, 2020Publication date: October 29, 2020Inventors: Jingjing ZHU, Songyun XU, Mian LI, Chang PENG, Yirong GONG
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Publication number: 20200339907Abstract: A lubricant formulation for an electric or hybrid vehicle includes a base oil, or a blend thereof, one or more additives, and a molybdenum amine complex, such as diisotridecylamine molybdate, are provided. Lubricant formulations can be characterized by one of: improving electric motor protection when a volatage is applied to an electrode in the presence of a formulation comprising the diisotridecylamine molybdate additive as compared to a fluid lacking the diisotridecylamine molybdate additive; maintaining the electrical resistance slope of a formulation comprising the diisotridecylamine molybdate additive as compared to a fluid lacking the diisotridecylamine molybdate additive; the formulation forming a protective film on copper surfaces; a change in color of the formulation indicating contact load, temperature, time, or viscosity change.Type: ApplicationFiled: April 26, 2020Publication date: October 29, 2020Inventors: Anant Kolekar, James Brown, Frances Lockwood, Dale Reid
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Publication number: 20200339908Abstract: The present invention provides an initial running-in agent composition suitable for forming a low-friction surface (running-in surface) on a sliding member, such as a hard carbon film, in a system in which water is used as a lubricant. The initial running-in agent composition (10) according to an embodiment of the present invention contains water 11 as a lubricant base and nanodiamond particles (12). In the initial running-in agent composition (10), a content of the water (11) is preferably 99 mass % or greater, and a content of the nanodiamond particles (12) is preferably 1.0 mass % or less.Type: ApplicationFiled: October 25, 2018Publication date: October 29, 2020Applicants: DAICEL CORPORATION, TOHOKU UNIVERSITYInventors: Norihiro KIMOTO, Tomohiro GOTO, Koshi ADACHI, Tsubasa TAKAHASHI
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Publication number: 20200339909Abstract: A method for extracting naturally occurring oil bodies (oleosomes) from a material containing naturally occurring oil bodies (oleosomes) includes the steps of dispersing the material containing oleosomes in an aqueous composition to thereby obtain an aqueous dispersion of material containing oleosomes, extracting oleosomes from the aqueous dispersion of material containing oleosomes to thereby obtain a crude oleosome extract and isolating crude oleosomes from the extract by drying the crude oleosome extract. The dried oleosome powder may be used with a personal care product, a pharmaceutical product or a food product.Type: ApplicationFiled: December 18, 2018Publication date: October 29, 2020Inventor: Konstantinos NIKIFORIDIS
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Publication number: 20200339910Abstract: The present disclosure is related to refining one or more grain oil composition streams (e.g., distillers corn oil or syrup) in a biorefinery to provide one or more refined grain oil products, where each grain oil product has targeted amounts of a free fatty acid component and the fatty acid alkyl ester component.Type: ApplicationFiled: May 21, 2020Publication date: October 29, 2020Inventors: Benjamin A. Lamprecht, Tyler L. Jordison, Alexander T. McCurdy, Steven T. Bly
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Publication number: 20200339911Abstract: A method of purifying biomass-based lipid material, as disclosed includes providing a feed of biomass-based lipid material; optionally drying the feed; removing oxygen from the feed under reduced pressure; heat treating the feed at 180 to 300° C. under reduced pressure to solidify at least part of phosphorous and/or metal containing impurities, simultaneously distilling off at least part of free fatty acids and low molecular weight nitrogen compounds, to obtain at least a fraction containing free fatty acids and low molecular weight nitrogen compounds, and heat treated biomass-based lipid material containing degraded phosphorous and/or metal containing impurities in solid form; and removing the solid degraded phosphorous and/or metal containing impurities from the second fraction.Type: ApplicationFiled: December 28, 2018Publication date: October 29, 2020Applicant: Neste OyjInventors: Jukka-Pekka PASANEN, Jarmo HALTTUNEN, Annika MALM, Väinö SIPPOLA
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Publication number: 20200339912Abstract: A stabilization composition for a scented candle formulation comprising: (A) an aromatic triazole compound of the formula (I) wherein R1 is a hydrocarbon chain of 4 to 12 carbon atoms, R2 is a hydrocarbon chain of 4 to 12 carbon atoms, and R3 is hydrogen or methyl; and (B) at least one longer wavelength UV light absorber, preferably a 2-(2?-Hydroxyphenyl)benzotriazole.Type: ApplicationFiled: April 20, 2020Publication date: October 29, 2020Applicant: Vanderbilt Chemicals, LLCInventor: Martin PAISNER
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Publication number: 20200339913Abstract: The need for a liquid hand-dishwashing composition which provides further improved sudsing volume and longevity when washing dishware using diluted liquid hand dishwashing compositions, especially in the presence of greasy soil and particulate soil, while still providing the desired cleaning, is met when the composition is formulated with from 5% to 50% of a sudsing surfactant system and polyvinyl alcohol having a viscosity of from 20 mPa·s to 55 mPa·s.Type: ApplicationFiled: April 24, 2020Publication date: October 29, 2020Inventors: Karl Ghislain BRAECKMAN, Denis Alfred GONZALES, Pieter Jan Maria SAVEYN, Frederik Clara P. VANDENBERGHE
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Publication number: 20200339914Abstract: The need for a liquid hand dishwashing cleaning composition that is less hazy, while also provides reduced surface tension between the detergent composition and the soiled plate, and hence improvements in cleaning, is met when the liquid hand dishwashing cleaning composition is formulated with a surfactant system and a polyvinyl alcohol having a degree of hydrolysis of from about 40% to about 86%.Type: ApplicationFiled: April 24, 2020Publication date: October 29, 2020Inventors: Karl Ghislain BRAECKMAN, Pieter Jan Maria SAVEYN, Mark Robert SIVIK, Evelyne Johanna Lutgarde VAN HECKE
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Publication number: 20200339915Abstract: The present disclosure relates to fabric-care compositions comprising an uncured silicone based polymer. In particular, the present disclosure relates to fabric-care compositions comprising at least one uncured silicone based polymer; and at least one fabric-care ingredient, optionally in an acceptable medium. Also disclosed are processes to prepare the fabric-care compositions and uses of the fabric-care compositions.Type: ApplicationFiled: December 17, 2018Publication date: October 29, 2020Inventors: Tatiana DIMITROVA, Jonathan THILL, Severine CAUVIN
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Publication number: 20200339916Abstract: A composition for removing spillage on asphalt paving of hydrocarbon substances which includes modifiers, chemical oxidizers and bacteria which metabolizes both the spillage and a softened top layer of asphalt paving to aid in rehardening the surface of the mat while not metabolizing the underlying asphalt paving unaffected by the spillage.Type: ApplicationFiled: March 16, 2020Publication date: October 29, 2020Inventors: Michael Zahajko, Michael Gregory Zahajko, Derek Zahajko, Kimball Garvin, Eric Jensen
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Publication number: 20200339917Abstract: The present invention relates to cleaning compositions including variants of an alpha-amylase and methods of treating surfaces such as textiles with aqueous liquor including such compositions, especially at low temperatures.Type: ApplicationFiled: July 17, 2020Publication date: October 29, 2020Inventors: Carsten ANDERSEN, Chakshusmathi GHADIYARAM, Padma Venkatachalam IYER, Rajendra Kulothungan SAINATHAN, Iben DAMAGER
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Publication number: 20200339918Abstract: The freshener revealed here is used for perfuming and freshening various objects and spaces. It comprises several components, one of which is in the form of a capsule which contains a fragrance. The capsule may be a microcapsule or a nanocapsule. It is applied by spraying directly on the fabric or surface. A pleasant, floral fragrance smells from the first application, however, the specificity of this freshener is noticeable after it is dried on the treated surface. After application by spraying and the time of drying, in physical contact with the treated surface the capsules break and release the fragrance into the space. This freshener is used on all types of textiles, leather, artificial leather, but also on hard and less absorbent surfaces. Mechanic force/friction (sitting, walking and the like) cause the breaking of the fragrant capsules that remain on the fibres, thereby obtaining the additional “boost” of fragrance.Type: ApplicationFiled: November 13, 2018Publication date: October 29, 2020Inventor: Ivo Domazet
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Publication number: 20200339919Abstract: This disclosure relates to compositions containing 1) at least one water soluble polar aprotic organic solvent; 2) at least one quaternary ammonium hydroxide; 3) at least one carboxylic acid; 4) at least one Group II metal cation; 5) at least one copper corrosion inhibitor selected from the group consisting of 6-substituted-2,4-diamino-1,3,5-triazines; and 6) water, in which the composition is free of a compound comprising at least three hydroxyl groups. The compositions can effectively strip positive or negative-tone resists or resist residues, and be non-corrosive to bumps and underlying metallization materials (such as SnAg, CuNiSn, CuCoCu, CoSn, Ni, Cu, Al, W, Sn, Co, and the like) on a semiconductor substrate.Type: ApplicationFiled: April 16, 2020Publication date: October 29, 2020Inventors: Atsushi Mizutani, William A. Wojtczak, Yasuo Sugishima, Raj Sakamuri
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Publication number: 20200339920Abstract: The present disclosure relates to pouches made from a combination of chemically different water-soluble films and containing household care compositions that are at least partially enclosed by the water-soluble films in at least one compartment.Type: ApplicationFiled: July 13, 2020Publication date: October 29, 2020Inventors: Florence Catherine COURCHAY, Regine LABEQUE, Steven George FRIEDRICH, David M. LEE, Shinsuke NII, Lee Kon YEUNG, Thomas J. YOGAN, Marc Rene Bert RENMANS
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Publication number: 20200339921Abstract: A hazardous drug deactivation wipe kit includes a first pouch having a one-way valve coupled to an end thereof, a second pouch, and a third pouch. The first pouch contains a wipe saturated in a hypochlorite solution, the second pouch contains a wipe saturated in thiosulfate solution, and the third pouch contains a wipe saturated in isopropyl alcohol solution. The deactivation wipe kit may be used in a clean room to deactivate most hazardous drugs on a work surface.Type: ApplicationFiled: July 10, 2020Publication date: October 29, 2020Inventors: Mark J. Compo, Michael BALESTRI
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Publication number: 20200339922Abstract: The present invention provides a powdered vinegar that comprises partly neutralized vinegar, i.e. vinegar derived acid that is partly neutralized with e.g. sodium and/or potassium hydroxide, and free vinegar derived acid. The invention also provides a process for producing such a powdered vinegar and the use of this powdered vinegar in a foodstuff or a beverage, e.g. as a preservative. The present process offers the advantage that it yields a stable, free flowing powdered vinegar that can suitably be used as a preservative in e.g. processed meat products. The powdered vinegar has a high content of free acid, is easy to dissolve and acts as an acidulant.Type: ApplicationFiled: July 14, 2020Publication date: October 29, 2020Applicant: Purac Biochem B.V.Inventors: Renee Boerefijn, Marija Orlovic, Kees Van Der Voort Maarschalk
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Publication number: 20200339923Abstract: Disclosed is a method for preparing a grape wine vinegar and a grape wine vinegar using the same, and more particularly a preparation method for grape wine vinegar and a grape wine vinegar using the same, which involves performing an alcoholic fermentation using grapes and yeast, followed by an aging process, and then introducing a vinegar starter into grape wine to cause an acetic fermentation, thereby creating a grape wine vinegar with improved taste and flavor and many health benefits due to high contents of organic acid and antioxidant components in addition to the ether component of grapes.Type: ApplicationFiled: June 13, 2019Publication date: October 29, 2020Applicant: Vineko Argo Co., Ltd.Inventor: Sung Mi KIM
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Publication number: 20200339924Abstract: Disclosed is a mass-cultivation system for microalgae, including a reactor that contains a cultivation liquid in the interior thereof, wherein the liquid includes functional particles. According to the mass-cultivation system for microalgae according to the present invention, because various functions that are necessary for cultivation of microalgae may be uniformly distributed in a cultivation liquid by allowing functional particles having various functions to flow in the cultivation liquid, a suitable environment may be created based on the cultivation of a large amount of microalgae and the growth of microalgae so that a high efficiency cultivation system may be realized while the problems of mass-cultivation of an existing cultivation system may be solved.Type: ApplicationFiled: June 17, 2020Publication date: October 29, 2020Inventors: Uen Do LEE, Won YANG, Byung Ryeul BANG, Su Ji JEON
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Publication number: 20200339925Abstract: A device made from a hydrogel matrix is provided. The hydrogel matrix includes a photoabsorber with a void architecture in the matrix, having a first vessel architecture and a second vessel architecture that are each tubular and branching, wherein the first and second vessel architectures are fluidically independent from each other. A pre-polymerization solution for forming the device, and methods of fabricating such devices are described. A method of fabricating a 3D hydrogel construct is provided. The method includes using a computer-implemented process to create a 3D model of the construct based on a tessellation of polyhedra having a number of faces connected by edges and vertices, generate a first vascular component of the model, generate a second vascular component of the model, and combine the first and second vascular components of the model.Type: ApplicationFiled: April 27, 2020Publication date: October 29, 2020Inventors: Jordan Miller, Bagrat Grigoryan
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Publication number: 20200339926Abstract: A petri dish has interlock features between the lid and dish that allow single-handed engagement of the lid with the dish by rotation, so that the lid and dish may be raised by grasping only the lid without stabilization of the dish with a second hand. Disengagement is similarly single-handed.Type: ApplicationFiled: April 22, 2020Publication date: October 29, 2020Inventors: Aleksandar Relja Wood, Harpreet Singh
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Publication number: 20200339927Abstract: The invention describes a gas permeable fluoropolymer and silicone material used in the construction of cell culture bags.Type: ApplicationFiled: July 14, 2020Publication date: October 29, 2020Inventors: Sarah Louise Clark, Natasha Anna Lundgren, Michael John Tzivanis, Aijun Zhu
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Publication number: 20200339928Abstract: A fluid handling apparatus having a two-sided channel plate with channel ports extending from one side to the other. Fluid channels on both sides of the channel plate connected to the channel ports direct fluid through the channel plate in a desired fluid path, and the first face and the second face of the channel plate are sealed to fluidly encase the fluid channels.Type: ApplicationFiled: January 18, 2019Publication date: October 29, 2020Inventors: Espir Kahatt, Chris Harder, Louwrens Stassen, Marie Ashman, Peter Goodings, Saakshi Sutarwala
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Publication number: 20200339929Abstract: The present invention relates to a cell mounting module device, which comprises a body portion having a container form of which upper and lower portions are opened and an inside is empty, a cap portion which includes an upper cap and a lower cap coupled to opened upper and lower ends of the upper and lower portions of the body portion to be opened and closed, respectively, and has a syringe coupling member formed at a center of the lower cap, a cell accommodating portion which is installed in the body portion and accommodates cells injected through the opened upper portion of the body portion, and a cell mounding module portion which is installed below the cell accommodating portion and includes a microstructure for mounting the cells accommodated in the cell accommodating portion.Type: ApplicationFiled: September 9, 2019Publication date: October 29, 2020Applicant: Biot Korea Inc.Inventors: Yeong Jun CHANG, Sung Kuk PARK, Tae Yong KIM
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Publication number: 20200339930Abstract: A cell culture device includes a plurality of culture containers that divide and accommodate a cell suspension; a treatment part that performs a treatment on a certain amount, which corresponds to each of units of treatment, of at least one of a cell suspension accommodated in a culture container, or cells contained in the cell suspension accommodated in the culture container; a mixing part that mixes cell suspensions which are treated in the treatment part and which respectively correspond to each of the plurality of units of treatment; a stirring part that stirs the cell suspension mixed in the mixing part; and a transfer control unit that controls a transfer of the cell suspension to the treatment part, the mixing part, and the stirring part.Type: ApplicationFiled: July 14, 2020Publication date: October 29, 2020Applicant: FUJIFILM CorporationInventors: Atsushi INADA, Hidetoshi TAKAYAMA
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Publication number: 20200339931Abstract: A bioreactor for use on a moving platform comprises a bag. According to a first aspect, the bag defines a three-dimensional geometrical shape including at least one lower collecting vertex in which at least two edges of the geometrical shape meet at an angle which is preferably not greater than 90°. The bioreactor further includes at least one port or sensor, preferably a biomass sensor, arranged in the vicinity of the collecting vertex. According to a second aspect, the bag defines a two-dimensional geometrical shape or a three-dimensional geometrical shape. The geometrical shape includes at least one edge, in which at least two faces of the geometrical shape meet at an angle which is preferably not greater than 90°. A longitudinal port/sensor element is arranged along the edge and includes several ports and/or sensors. A bioreactor motion system comprises a moving platform and a bioreactor according to the first or second aspect.Type: ApplicationFiled: April 24, 2020Publication date: October 29, 2020Inventors: Gregory BREMER, Clint KUKLA, Thorsten ADAMS, Fabian TUNZINI, Rachel DELESSERT, Michael BATES
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Publication number: 20200339932Abstract: The subject invention provides for continuous production of advantageous microbes and/or by-products using a system capable of submerged fermentation, solid-state fermentation, and combinations thereof. In particular, the systems utilize cassettes or other similar containers as vessels for holding a solid substrate inoculated with a microorganism. The cassettes are aligned inside a tank, and the tank can optionally be filled with a liquid nutrient medium. The cassettes with substrate and growing microorganisms are removed from the tank for harvesting the microorganism, and a new, sterilized cassette with substrate can be replaced into the tank.Type: ApplicationFiled: January 15, 2019Publication date: October 29, 2020Inventors: Sean FARMER, Ken ALIBEK, Tyler DIXON, Nicholas CALLOW, Timur ALIBEK
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Publication number: 20200339933Abstract: The present invention relates to a device (1) for the treatment of biological material (2) comprising a concentration circuit (3) having at least one concentration filter (20), at least one supply conduit (30) of the biological material (2), and a concentration section (40) interposed between separation filter (10) and concentration filter (20) and defining an inner volume configured to accommodate a fraction of interest (2a) of the biological material (2). A discharge conduit (50) is connected to the second access (22) of the concentration filter (20) downstream of the concentration section (40), and an infusion line (60) is connected to the concentration circuit (3). The concentrated fraction of interest (2a) of biological material (2) may be withdrawn from a collection channel (70) or by removing the entire concentration section (40) from the rest of the circuit.Type: ApplicationFiled: April 29, 2020Publication date: October 29, 2020Inventors: Antonio BOSETTO, Paolo PIRAZZOLI
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Publication number: 20200339934Abstract: The present invention provides a cell culture base that avoids contact between a photoresponsive layer and cells. The cell culture base of the present invention includes: a support layer; a photoresponsive layer; and a cell culture layer, wherein the photoresponsive layer is laminated on the support layer, the cell culture layer is laminated on the photoresponsive layer, the photoresponsive layer contains a photoresponsive substance that causes at least one of heat and change in magnetism by light irradiation, and the cell culture layer is capable of culturing cells.Type: ApplicationFiled: April 20, 2020Publication date: October 29, 2020Inventor: Junichi MATSUMOTO
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Publication number: 20200339935Abstract: A pretreatment method for cell transfer is a pretreatment method to be performed for transferring a required cell to a predetermined transfer destination by picking the cell, from a mass containing a plurality of cells of different sizes, using a cell transfer device including cell picking means. The pretreatment method includes a classification step of classifying the required cell, from among the plurality of cells contained in the mass, into at least two groups according to a size of the cell; and a supply step of supplying the classified cells, in a state of being individually classified, to a position where picking can be conducted by the picking means.Type: ApplicationFiled: March 8, 2018Publication date: October 29, 2020Applicant: YAMAHA HATSUDOKI KABUSHIKI KAISHAInventors: Yohei IZUME, Masaru SAKAMOTO
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Publication number: 20200339936Abstract: A cell mechanical stimulating device for applying to at least one cell sample is provided. The device includes a base unit, at least one moving component and at least one magnetic component. The base unit includes a base body and a separating lid. The base body includes at least one culturing chamber and a bottom chamber surface. The cell sample is disposed in the culturing chamber, and the separating lid encloses the culturing chamber. The magnetic component drives the moving component to shift between a pressurizing position and a non-pressurizing position. At the pressurizing position, the moving component moves toward the bottom chamber surface and pressurizes the cell sample. At the non-pressurizing position, the moving component moves toward the separating lid and the pressure on the cell sample is removed. The cell sample is pressurized by the magnetic component driving the moving component.Type: ApplicationFiled: April 23, 2020Publication date: October 29, 2020Applicant: China Medical UniversityInventors: Dan-Jae Lin, Ming-Tzu Tsai, Chao-Wei Hung, Yi-Tao Chang, Chun-Hsu Yao
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Publication number: 20200339937Abstract: A system for incubating one or more cells and/or organotypic cultures for biological investigation, in particular for toxicology assessment, comprising a bio-incubator and a pressure system fluidly connected with the bio-incubator. The pressure system is a cyclic gas pressure system configured for cyclically varying the gas pressure in the bio-incubator between a negative pressure and a positive pressure compared to the atmospheric pressure, so as to reproduce the pressure conditions in lungs of a living mammal. The system is remarkable in that the cyclic gas pressure system comprises a feedthrough with a pipe configured to deviate the air influx from the one or more cells and/or organotypic cultures.Type: ApplicationFiled: December 31, 2018Publication date: October 29, 2020Inventors: Arno GUTLEB, Tommaso SERCHI, Mathieu GERARD
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Publication number: 20200339938Abstract: There is disclosed a cell culture plate comprising at least two sequentially arranged wells and a channel adapted for fluid communication between the wells, wherein the channel is connected or coupled to a first pump via openings at each end of the channel, and wherein said first pump is operable to circulate fluid between the at least two wells. Devices and systems incorporating the cell culture plate and methods and uses employing same are also disclosed.Type: ApplicationFiled: August 30, 2018Publication date: October 29, 2020Inventors: David Bovard, Julia Hoeng, Shoaib Majeed, Antonin Sandoz
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Publication number: 20200339939Abstract: A cell analyzing device includes a control circuit. The control circuit acquires data of an observation image. The control circuit specifies a colony of a cultured cell in the observation image. The control circuit calculates a ratio at which the cultured cell occupies a predetermined range included in the observation image as an occupancy rate. The control circuit calculates a size of the colony. The control circuit determines a state of the cultured cell based on the occupancy rate and the size of the colony.Type: ApplicationFiled: July 15, 2020Publication date: October 29, 2020Applicant: OLYMPUS CORPORATIONInventors: Yasunobu IGA, Taiji MINE, Yoshinobu AKAHORI
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Publication number: 20200339940Abstract: An extraction method is aimed at extracting an object component by transferring the object component from a first liquid containing a microorganism and the object component to a second liquid to which the object component can be transferred and that is capable of causing phase separation from the first liquid, with use of a flow channel including a merging part, a flow part, and an outlet part. The extraction method includes a step of supplying the first liquid to the merging part, a step of supplying the second liquid to the merging part, a step of passing the first liquid and the second liquid supplied to the merging part, through the flow part, in a state where a phase of the first liquid and a phase of the second liquid are separated from each other, a step of discharging the first liquid and the second liquid passed through the flow part, from the outlet part, and a step of collecting the first liquid and the second liquid discharged from the outlet part, into a collector.Type: ApplicationFiled: July 14, 2020Publication date: October 29, 2020Applicant: AJINOMOTO CO., INC.Inventors: Satoshi Hioki, Ayumi Nakajima, Nobuhisa Nitta
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Publication number: 20200339941Abstract: Bacterial strain Clostridium histolyticum was deposited in CCM (Czech Collection of Microorganisms at Masaryk University, Faculty of Science) under No. CCM 8656. This strain produces proteolytic enzymes including collagenase, elastinase, neutral proteases and clostripain under anaerobic conditions at a temperature from 25° C. to 45° C. The strain is used for the production of a mixture of two collagenases, col 1 and col 2, with molecular weight 116 kDa and 126 kDa, and possibly clostripain. The mixture of the above-mentioned collagenases and possibly clostripain obtained from the above-mentioned strain is used for the isolation of Langerhans islets.Type: ApplicationFiled: September 11, 2018Publication date: October 29, 2020Applicant: MB Pharma s.r.o.Inventors: Marek MOSA, Martin BENESIK
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Publication number: 20200339942Abstract: A method for preparing a shelf stable spore-containing probiotic alimentary additive is disclosed, the method including providing a liquid slurry including spores from at least one spore-forming probiotic bacterial strain, a saccharide, and a humectant; and pasteurizing the liquid slurry to yield the alimentary additive. The alimentary additive may have a water activity (Aw) of less than about 0.7. The alimentary additive may have a pH from about 2.0 to 9.5. A plurality of the spores may remain in an un-germinated state and uniformly suspended for at least two months after the pasteurizing to yield a shelf stable spore-containing probiotic alimentary additive.Type: ApplicationFiled: April 23, 2020Publication date: October 29, 2020Applicant: Kerry Luxembourg S.à.r.l.Inventors: Benjamin GEORGE, Howard CASH, Joseph M. BRADLEY, Nusair IMAM, Stephen G. COBBE, Eileen O'SHEA
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Publication number: 20200339943Abstract: Methods and compositions for enhancing or promoting germination of bacterial spores, and yeasts are disclosed herein. The composition of the present invention comprises an extract obtained from banana or any member belonging to the genus Musa that may be used alone or in a growth medium to promote and enhance germination of bacterial spores, growth of bacterial, yeast, and fungal cell cultures.Type: ApplicationFiled: June 12, 2020Publication date: October 29, 2020Inventor: Mark Lyte
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Publication number: 20200339944Abstract: Described herein are improved media for culturing immune cells, and methods of use thereof. In particular, cell growth media described herein are particularly suitable for T-cell expansion, which can be used for manufacture of cells useful in adoptive cell therapies, including therapies using chimeric antigen receptors (e.g., CAR-T cell therapy).Type: ApplicationFiled: April 24, 2020Publication date: October 29, 2020Inventors: Diego A. VARGAS-INCHAUSTEGUI, Thomas Charles PERTEL, Barbra Johnson SASU
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Publication number: 20200339945Abstract: Cell cultures comprising poly(oxazoline) stabilizers and use of poly-(oxazolines for stabilizing cell cultures Described are cell cultures containing in a cell culture medium one or more water-soluble poly(oxazolines). The water-soluble poly(oxazoline) acts as a stabilizer for the cells and reduces the mechanical stress exerted by agitating the cell culture medium on the cells. This leads to an improved survival rate of the cells compared to the unstabilized state.Type: ApplicationFiled: May 28, 2018Publication date: October 29, 2020Inventors: Meike Nicole LEISKE, Anja TRÄGER, Ulrich Sigmar SCHUBERT
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Publication number: 20200339946Abstract: The present invention relates to A multicomponent system wherein a first component is an engineered antigen-presenting cell (eAPC) designated component A and a second component is a genetic donor vector, designated component C, for delivery of one or more ORFs encoding an analyte antigen-presenting complex (aAPX) and/or an analyte antigenic molecule (aAM), wherein component A a. Lacks endogenous surface expression of at least one family of aAPX and/or aAM and b. Contains at least two genomic receiver sites, designated component B and component D, each for integration of at least one ORF encoding at least one aAPX and/or aAM, and component C is matched to a component B, and wherein component C is designed to deliver c. A single ORF encoding at least one aAPX and/or aAM or d. Two or more ORF encoding at least one aAPX and/or aAM, wherein the genomic receiver sites B and D are synthetic constructs designed for recombinase mediated exchange (RMCE).Type: ApplicationFiled: April 30, 2020Publication date: October 29, 2020Applicant: GENOVIE ABInventors: Reagan Micheal Jarvis, Ryan Edward HILL, Luke Benjamin PASE
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Publication number: 20200339947Abstract: The present invention relates to mesenchymal stromal cells and to an advantageous method for their isolation from umbilical cord. In particular, the cells are obtainable by a method comprising isolating the stromal Wharton's Jelly or a fraction thereof from an umbilical cord and subjecting the stromal Wharton's Jelly or fraction thereof to enzymatic treatment, thereby releasing at least one cell from the stromal Wharton's Jelly or fraction thereof. Preferably, cultivation of cells occurs under conditions allowing the expansion of the cell population. The cell population according to the present invention has proliferative properties and is of industrial interest for a variety of purposes.Type: ApplicationFiled: December 21, 2018Publication date: October 29, 2020Inventors: Diego ARDIGO', Giovanni MILAZZO, Massimo DOMINICI, Alba MURGIA
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Publication number: 20200339948Abstract: The present invention relates to a medium composition for improving stem cell migration, which includes ethionamide, and a use thereof. According to the present invention, the migration of stem cells may be effectively improved by the adjustment of a culture environment, which is a simple and safe method, without using gene manipulation or a viral vector, and the stem cells improved in migration by the method may be effectively used as a stem cell therapeutic agent that is able to function by rapidly migrating to the damaged region after transplantation.Type: ApplicationFiled: October 8, 2018Publication date: October 29, 2020Inventors: Duk Lyul NA, Jong Wook CHANG, Hyo Jin SON