Patents Issued in November 12, 2020
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Publication number: 20200352425Abstract: Systems and methods for visualizing ablated tissue are disclosed. In some embodiments, a system for imaging tissue comprising: a catheter having a distal end and a proximal end; an inflatable balloon disposed about the distal end of the catheter; and an optical housing extending from the distal end of the catheter into the balloon, the optical housing being configured to position inside the balloon a light source for illuminating a tissue outside the balloon and a camera for imaging the illuminated tissue.Type: ApplicationFiled: May 21, 2020Publication date: November 12, 2020Inventors: Omar Amirana, Kenneth C. Armstrong, Matthew W. Kay, Marco A. Mercader, Terrance J. Ransbury, Narine Sarvazyan
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Publication number: 20200352426Abstract: A cleaning tool for endoscope that cleans and disinfects a distal end constituent member provided in a distal end portion in an insertion section in an endoscope includes two components, and is configured to cover an entire periphery of the distal end constituent member by combining the two components, in which the two components are respectively provided with hinges configured to make the two components openable and closable by connecting the two components to each other, the hinge being configured to be separated from each other when an opening angle between the two components exceeds a predetermined angle.Type: ApplicationFiled: July 23, 2020Publication date: November 12, 2020Applicant: OLYMPUS CORPORATIONInventors: Takuya TOYOOKA, Tomokazu IWASAKI
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Publication number: 20200352427Abstract: A surgical instrument comprises a heat generating component, a heat sink, an elongate shaft extending from the heat generating component to the heat sink, and an elongate thermal conduit extending within the elongate shaft between the heat generating component and the heat sink. The surgical instrument also comprises a movable contact structure thermally coupled between the elongate thermal conduit and the heat generating component. The elongate thermal conduit extends into the movable contact structure and the movable contact structure is movable relative to the heat generating component.Type: ApplicationFiled: May 22, 2020Publication date: November 12, 2020Inventor: Rumen Deyanov
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Publication number: 20200352428Abstract: An endoscope provides a connector substrate of an endoscope connector to be connected to a processor with a temperature sensor for directly measuring a temperature of the connector substrate, performs control to restrict a power supply (in other words, limit and stop a power supply) from an endoscope power supply circuit according to the measured temperature of the connector substrate (in other words, the endoscope connector), and thereby appropriately manages the temperature of the endoscope connector in the endoscope.Type: ApplicationFiled: July 27, 2020Publication date: November 12, 2020Applicant: OLYMPUS CORPORATIONInventors: Norihito YAMADA, Madoka SAITO, Shigetoshi FUTAMI
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Publication number: 20200352429Abstract: An intubation device for use in an endotracheal intubation procedure includes: a laryngoscope blade having a tip and a base; a handle attached to the base of the blade; a channel, the channel including a blade channel portion extending along the blade substantially from the tip to the base and including an outlet proximate to the tip and a handle channel portion extending partially along the handle from the blade channel portion; and a tube movement mechanism in the handle, the tube movement mechanism including a thumb interface.Type: ApplicationFiled: December 9, 2019Publication date: November 12, 2020Inventor: Julio Miguel Alonso Babarro
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Publication number: 20200352430Abstract: In some embodiment, the present invention is directed to a device for obtaining samples from a subject. In other embodiments, methods and devices of the present invention allow the evaluation of conditions of the gastrointestinal tract of a subject. Measurements may be utilized, for example, to diagnose a disease of the esophagus, to monitor inflammation of the esophagus, or to access the treatment of a disease of the esophagus. In one embodiment, the invention comprises a method for measuring esophageal inflammation comprising deploying a device into the esophagus of a subject, removing the device after a predetermined period of time, analyzing the device for a diagnostic indicator of esophageal inflammation and evaluating the diagnostic indicator to diagnose esophageal inflammation.Type: ApplicationFiled: May 11, 2020Publication date: November 12, 2020Inventors: Glenn T. Furuta, Steven J. Ackerman
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Publication number: 20200352431Abstract: A system for performing minimally invasive procedures in a working space within a body lumen of a patient including a flexible catheter configured to receive a working instrument therethrough. The flexible catheter has a working space expanding system positioned at the distal portion, the working space expanding system including first and second flexible elements movable from a non-expanded insertion position to an expanded position forming an expanded region to expand the working space within the body. The first and second flexible elements are connected at a distal region by a coupling structure. A stabilizing member stabilizes the distal portion of the flexible catheter.Type: ApplicationFiled: July 23, 2020Publication date: November 12, 2020Inventor: Gregory Piskun
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Publication number: 20200352432Abstract: An ophthalmic instrument including a light emitter, an optical system, and a control section. The light emitter includes a light source including at least one out of a first light source unit or a second light source unit that emits light for examining a subject eye. The light emitter is configured to emit light from the light source. The optical system guides light emitted from the light emitter onto a right-eye retina and/or onto a left-eye retina. The control section is configured to control the light emitter and the optical system such that the light is shone onto the right-eye retina and/or onto the left-eye retina.Type: ApplicationFiled: September 11, 2018Publication date: November 12, 2020Applicant: NIKON CORPORATIONInventors: Hideki OBARA, Ken TOMIOKA, Shota MIYAZAKI
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Publication number: 20200352433Abstract: In some embodiments, an ophthalmic laser system may be provided that does not include a traditional laser console. Instead, the treatment device may be configured to house the treatment light source within the device handle. Additionally, in some embodiments, the handheld treatment device may include a user interface, such as dials and buttons, for adjusting various parameters of the therapeutic light. With certain embodiments, the self-contained handheld treatment device may be operated independent of an AC power source. For example, in some embodiments, the handheld treatment device may be battery powered. Additionally, the handheld treatment device may be disposable or may utilize replaceable distal tips in certain embodiments. Certain embodiments may be particularly designed for transscleral cyclophotocoagulation. Also, treatment guides are provided that may be configured to couple with a treatment device to align the device with a target tissue of the eye.Type: ApplicationFiled: July 24, 2020Publication date: November 12, 2020Applicant: IRIDEX CorporationInventors: Howard Chen, David Buzawa
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Publication number: 20200352434Abstract: The present disclosure provides an improved method for photobleaching an eye of a subject. The disclosed method may be used in a number of psychophysical test methods, including, but not limited to, measurement of dark adaptation. The improved method for photobleaching involves at least one of the following improvements: (i) the use of a bleaching light emitting a particular wavelength of light or a tailored spectrum of wavelengths; (ii) restricting or otherwise spatially tailoring the region of the retina that is subject to photobleaching; and (iii) utilizing a bleaching light having an intensity that is at or below the intensity of ambient daylight. The present disclosure additionally provides a combination of a photobleaching light and an apparatus to administer a psychophysical test suitable for use in practicing the disclosed methods.Type: ApplicationFiled: July 28, 2020Publication date: November 12, 2020Inventors: John G. EDWARDS, Gregory R. JACKSON
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Publication number: 20200352435Abstract: An ophthalmologic apparatus includes a refractive power measurement optical system, a fixation projection system, an inspection optical system, and a controller. The refractive power measurement optical system includes a first focusing element capable of changing a focal position, and is configured to project first light onto a subject's eye and to detect returning light of the first light from the subject's eye via the first focusing element. The fixation projection system is configured to project fixation light target onto the subject's eye. The inspection optical system includes a second focusing element capable of changing a focal position in conjunction with the first focusing element, and is used for a predetermined inspection in which second light is projected onto at least the subject's eye via the second focusing element.Type: ApplicationFiled: July 24, 2020Publication date: November 12, 2020Applicant: TOPCON CORPORATIONInventors: Yoko TATARA, Michiko NAKANISHI, Shunichi MORISHIMA
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Publication number: 20200352436Abstract: Consumer products such as refraction measurement devices may be used for obtaining refraction measurements allow consumers to track their vision without visiting an optometrist or ophthalmologist. Such consumer products may work in concert with smart phones or other products having a touch screens that present images to refraction measurement devices. Smart phones may have resolution rates, sometimes measured as PPI or pixels per inch that are unknown to the user and/or refraction measurement device. On aspect of the invention is to provide an optical interface for the user to manually match the view port boundary of the smartphone to comport with the view port boundary of the refraction measurement device. Another aspect of the invention is the use of pre-distortion in images presented to the user. By noting the corrective movements exerted by the user upon the refractive measurement device, the user's own refractive error can be derived.Type: ApplicationFiled: July 22, 2020Publication date: November 12, 2020Inventors: Noam Sapiens, John Serri, Johan Borglin
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Publication number: 20200352437Abstract: Systems and methods are provided for performing optical coherence tomography angiography for the rapid generation of en face images. According to one example embodiment, differential interferograms obtained using a spectral domain or swept source optical coherence tomography system are convolved with a Gabor filter, where the Gabor filter is computed according to an estimated surface depth of the tissue surface. The Gabor-convolved differential interferogram is processed to produce an en face image, without requiring the performing of a fast Fourier transform and k-space resampling. In another example embodiment, two interferograms are separately convolved with a Gabor filter, and the amplitudes of the Gabor-convolved interferograms are subtracted to generate a differential Gabor-convolved interferogram amplitude frame, which is then further processed to generate an en face image in the absence of performing a fast Fourier transform and k-space resampling.Type: ApplicationFiled: November 16, 2018Publication date: November 12, 2020Inventors: VICTOR X.D. YANG, CHAOLIANG CHEN
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Publication number: 20200352438Abstract: A system includes a monitor configured to be coupled to multiple sensors over time to monitor one or more physiological characteristics of one or more patients, and including an information collection system configured to store in a database unique sensor identifying information and information related to plural uses of the same sensor.Type: ApplicationFiled: July 27, 2020Publication date: November 12, 2020Inventors: Daniel Lisogurski, Rakesh Sethi
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Publication number: 20200352439Abstract: Provided are a localization system and method useful in the acquisition and analysis of cardiac information. The localization system and method can be used with systems that perform cardiac mapping, diagnosis and treatment of cardiac abnormalities, as examples, and in the retrieval, processing, and interpretation of such types of information. The localization system and method use high impedance inputs, improved isolation, and relatively high drive currents for pairs of electrodes used to establish a multi-axis coordinate system. The axes can be rotated and scaled to improve localization.Type: ApplicationFiled: April 15, 2020Publication date: November 12, 2020Inventors: Daniel J. Welsh, Marcus F. Julian, Graydon E. Beatty, Xinwei Shi, Derrick R. Chou, Randell L. Werneth, J. Christopher Flaherty, Mark MacGregor
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Publication number: 20200352440Abstract: Medical system for remote monitoring, analysis and prognosis of patient's condition by series of at least first-lead electrocardiograms (ECGs), comprises: unit for gathering for each patient a series of ECGs; unit for extracting from the gathered database an ECG subset of a target group of patients, in accordance with at least one of identifiers according to examination purpose; unit for clustering the extracted ECG subset based on the feature of similarity of their forms; unit for determining an ECG form similarity measure in the space of ECG form features associates each ECG with a discretized ECG (DECG), which is a point having coordinates in at least one space of ECG form features; unit for generating STANDARDS for each cluster; unit for assessing variation in patient's condition over time by temporal variation in distances between each newly received DECGs in patient's DECG series and assigned at least one STANDARD.Type: ApplicationFiled: January 31, 2018Publication date: November 12, 2020Applicant: ZAKRYTOE AKTSIONERNOE OBSCHESTVO "EC-LEASING"Inventors: Alexander Viktorovich SHMID, Andrey Alexandrovich BEREZIN, Maxim Alexandrovich NOVOPASHIN
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Publication number: 20200352441Abstract: A novel implantable device to reliably record and transmit physiological signals from a subject was described. Design of the device to capture the signals, compress them, transmit via multiple techniques and to interpret the data are shown. Furthermore, the design and operation of the device in a typical setting are taught and the resulting implementation is presented.Type: ApplicationFiled: May 8, 2019Publication date: November 12, 2020Inventors: Orhan Soykan, Quan Ni, Mark Alan Christopherson
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Publication number: 20200352442Abstract: In a method for synchronous magnetic resonance (MR) imaging and radiation therapy using a combined system having a radiation apparatus and an MR imaging apparatus, wherein the system is designed to record MR signals of a subject during irradiation of the subject, a three-dimensional MR volume data set of the subject is acquired that contains a target volume for the irradiation, the location of a central beam of the radiation therapy apparatus relative to the subject, is continuously determined, and a second MR image data set is determined, which is positioned essentially perpendicular to the central beam. If the location of the central beam changes, a correspondingly changed second MR image data set is determined perpendicular to the central beam.Type: ApplicationFiled: July 27, 2020Publication date: November 12, 2020Applicant: Siemens Healthcare GmbHInventors: David Grodzki, Arne Hengerer, Sebastian Schmidt
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Publication number: 20200352443Abstract: Methods and apparatus for providing a functional mapping of a brain lesion in a patient's brain. The method comprises determining using a computer processor, based on human connectome data stored on at least one computer datastore in communication with the computer processor, at least one functional network associated with a location of a brain lesion identified in an image of a patient's brain. The at least one functional network includes a plurality of brain areas functionally connected to the location of the brain lesion and a plurality of correlation measures. Each of the correlation measures indicates a strength of functional connection between the location of the brain lesion and a respective brain area of the plurality of brain areas in the at least one functional network. The method further comprises determining, based at least one functional network, a likelihood that the brain lesion is causing one or more patient symptoms.Type: ApplicationFiled: July 28, 2017Publication date: November 12, 2020Applicant: Beth Israel Deaconess Medical Center, Inc.Inventor: Michael D. Fox
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Publication number: 20200352444Abstract: Systems and methods for spatial optimization of blood measurements in tissue are disclosed. Exemplary methods include: measuring a first Raman signal from the tissue with a probe at a first position; calculating a first percentage of a blood component in the first Raman signal; moving the probe a predetermined distance to a second position; measuring a second Raman signal with the probe at the second position; calculating a second percentage of the blood component in the second Raman signal; moving the probe the predetermined distance to a third position when the second percentage is greater than the first percentage; measuring a third Raman signal with the probe at the third position; calculating a third percentage of the blood component in the third Raman signal; moving the probe to the second position when the third percentage is less than the second percentage; and taking spectral measurements from the second position.Type: ApplicationFiled: May 7, 2019Publication date: November 12, 2020Inventors: Clint Periaki, Wei Yang, Jiani Huang
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Publication number: 20200352445Abstract: An exemplary photodetector system includes a plurality of photodetectors connected in parallel and a processor communicatively coupled to the plurality of photodetectors. The processor is configured to receive an accumulated output from the plurality of photodetectors. The accumulated output represents an accumulation of respective outputs from each of the plurality of photodetectors detecting photons during a predetermined measurement time period that occurs in response to a light pulse being directed toward a target within a body. The processor is further configured to determine, based on the accumulated output, a temporal distribution of photons detected by the plurality of photodetectors, and generate, based on the temporal distribution of photons, a histogram representing a light pulse response of the target within the body.Type: ApplicationFiled: April 9, 2020Publication date: November 12, 2020Inventors: Ryan Field, Bruno Do Valle, Jacob Dahle, Rong Jin, Sebastian Sorgenfrei
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Publication number: 20200352446Abstract: In part, the invention relates to methods, apparatus, and systems suitable for determining a fractional flow reserve (FFR) and variations of modifications thereof One embodiment relates to a method and apparatus for obtaining a corrected FFR in a vessel having a stenosis. In one aspect, the invention relates to an apparatus for measuring corrected FFR of a vessel having a stenosis. In one embodiment, the apparatus includes a probe comprising an optical coherence tomography assembly and a pressure assembly; and a processor in communication with the optical coherence tomography assembly and the pressure assembly. In one embodiment, the pressure assembly measures values of pressure in predetermined locations the vessel and communicates them to the processor. In one embodiment, a dual guidewire is used to reduce the interference in the pressure measurement.Type: ApplicationFiled: July 23, 2020Publication date: November 12, 2020Applicant: LightLab Imaging, Inc.Inventors: Christopher Petroff, Joseph M. Schmitt
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Publication number: 20200352447Abstract: A photoacoustic image of an object varies in contrast between a shallow portion and a deep portion according to the irradiation position of the object with respect to an ultrasonic probe. The present disclosure provides an information acquisition apparatus in which the contrast is high regardless of the depth of the region of interest. The information acquisition apparatus includes a varying unit that varies the irradiation position of the object with respect to the ultrasonic probe and controls the irradiation position according to an instruction on a condition for acquiring information on the object.Type: ApplicationFiled: October 25, 2017Publication date: November 12, 2020Inventor: Toshinobu Tokita
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Publication number: 20200352448Abstract: To provide an ultrasonic transmission instrument that can uniformly transmit ultrasonic waves in each direction around the instrument, even when the instrument is made of a material through which the ultrasonic waves cannot be transmitted. In an ultrasonic transmission instrument according to the invention, a light transmission member is disposed at an emission end of an optical waveguide, and an outer peripheral member covers an outer periphery of the light transmission member and is made of a light absorbing material.Type: ApplicationFiled: April 28, 2020Publication date: November 12, 2020Applicant: HITACHI, LTD.Inventors: Ryo IMAI, Tomohiko TANAKA
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Publication number: 20200352449Abstract: Provided are a resin material that provides a resin shaped article (such as a resin sheet) having an acoustic impedance close to that of a living body, a reduced acoustic wave attenuation even at high frequencies (such as 10 MHz), and high hardness and high tear strength, and that is suitable as a lens material for acoustic wave probes; an acoustic lens, an acoustic wave probe, an acoustic wave determination device, an ultrasound diagnostic apparatus, a photo-acoustic wave determination device, and an ultrasonic endoscope that employ the above-described resin material as a constituent material; and a method for producing the above-described acoustic lens.Type: ApplicationFiled: July 29, 2020Publication date: November 12, 2020Applicant: FUJIFILM CorporationInventors: Yuzo NAGATA, Yoshihiro NAKAI, Shigeki UEHIRA
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Publication number: 20200352450Abstract: Systems and methods are described herein for utilizing a photoacoustic sensor for estimating analyte concentration levels. Also described here are training methods for training an analyte sensor to more accurately estimate an analyte concentration level on the basis of a received acoustic signal.Type: ApplicationFiled: July 29, 2020Publication date: November 12, 2020Inventors: Li Zhou, Raymond M. Russell, Peter Schultz, Anuj M. Patel, Carol Chen, Roshanne Malekmadani, Lynette To, Hsiao-Yu S. Kow, Raghavendhar Gautham
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Publication number: 20200352451Abstract: A body temperature monitoring system for monitoring the body temperature continuously and providing alert in an event of detecting temperature irregularity is disclosed. The monitoring system includes a monitoring pad attachable to the human body for measuring the body temperature at various positions, and transmitting the collected data to the cloud system. The monitoring system further includes a cloud system having a database, and a mobile device having a transceiver, a processor, and a mobile application for configuring the monitoring system and receiving the alert. The database includes a device specific database and a clinical database, which facilitates the processor to identify a temperature irregularity when the measured body temperature is consistently outside an acceptable range of body temperature. The monitoring pad can be attached to the human body at various positions and accurately identify any temperature irregularity.Type: ApplicationFiled: May 7, 2019Publication date: November 12, 2020Inventor: Nam TSUI
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Publication number: 20200352452Abstract: A method for determining a view angle of a thermal image from a user and generating a suggestion to enable the user for adaptive positioning of a subject for capturing the thermal image is provided. The method includes (i) receiving a thermal image of a body of a subject, (ii) automatically determining a view angle of the thermal image from a user using a view angle estimator, (iii) determining an angular adjustment to be made to a view position of the thermal imaging camera or a position of the subject by comparing the determined view angle with a required view angle as per thermal imaging protocol when the thermal image does not meet the required view angle and (iv) generating instructions to the user for adjusting the view position of the thermal imaging camera for capturing a new thermal image at the required view angle as per thermal imaging protocol.Type: ApplicationFiled: July 28, 2019Publication date: November 12, 2020Inventors: Siva Teja Kakileti, Geetha Manjunath, Himanshu J. Madhu
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Publication number: 20200352453Abstract: A non-invasive electronic patient monitor tracks one or more physiological parameters of a patient, such as intravascular volume index (IVI), extravascular volume index (EVI), total hemoglobin (SpHb), impedance, and/or weight. The patient monitor determines if one or more of the physiological parameters are within a predetermined range. The patient monitor activates an alarm if one or more of the physiological parameters are outside the predetermined range and indicates a patient can be experiencing edema and/or heart failure, or sepsis.Type: ApplicationFiled: May 26, 2020Publication date: November 12, 2020Inventors: Paul Ronald Jansen, Michael O'Reilly
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Publication number: 20200352454Abstract: An electronic valve with: a yoke including an end plate portion and a side plate portion; a pole piece; a solenoid coil; and a diaphragm made of a plate-shaped magnetic material. The pole piece has an opening at one end portion and a first fluid inlet/outlet communicating with the opening at the other end portion. A biasing unit biases the diaphragm in a direction away from one end portion of the pole piece in a manner of moving the diaphragm translationally in one direction. In a non-operating time, the electronic valve comes into an open state where the opening is open. In an operating time, the diaphragm approaches the one end portion of the pole piece against the biasing force of the biasing unit by a magnetic force generated by the solenoid coil, and the electronic valve can come into a closed state where the opening is closed.Type: ApplicationFiled: July 30, 2020Publication date: November 12, 2020Applicant: OMRON HEALTHCARE CO., LTD.Inventors: Yoshihiko SANO, Takanori NISHIOKA, Hirofumi ONOHARA, Gaku KUBOTA
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Publication number: 20200352455Abstract: A handheld device measures all vital signs and some hemodynamic parameters from the human body and transmits measured information wirelessly to a web-based system, where the information can be analyzed by a clinician to help diagnose a patient. The system utilizes our discovery that bio-impedance signals used to determine vital signs and hemodynamic parameters can be measured over a conduction pathway extending from the patient's wrist to a location on their thoracic cavity, e.g. their chest or navel. The device's form factor can include re-usable electrode materials to reduce costs. Measurements made by the handheld device, which use the belly button as a ‘fiducial’ marker, facilitate consistent, daily measurements, thereby reducing positioning errors that reduce accuracy of standard impedance measurements. In this and other ways, the handheld device provides an effective tool for characterizing patients with chronic diseases, such as heart failure, renal disease, and hypertension.Type: ApplicationFiled: July 28, 2020Publication date: November 12, 2020Inventors: Matthew Banet, Marshal Singh Dhillon, Susan Meeks Pede, Lauren Nicole Miller Hayward, Arthur Deptala, Jonas Dean Cochran
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Publication number: 20200352456Abstract: A method of monitoring respiration with an acoustic measurement device, the acoustic measurement device having a sound transducer, the sound transducer configured to measure sound associated with airflow through a mammalian trachea, the method includes correlating the measured sound into a measurement of tidal volume and generating at least one from the group consisting of an alert and an alarm if the measured tidal volume falls outside of a predetermined range.Type: ApplicationFiled: July 24, 2020Publication date: November 12, 2020Inventors: Jeffrey I. Joseph, Marc C. Torjman, Denise L. Devine, Nance K. Dicciani, Channy Loeum
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Publication number: 20200352457Abstract: An electronic device according to an embodiment includes a speaker capable of outputting a sound wave, a sensor capable of acquiring an optical signal related to blood flow at a measured part of a user, and a controller configured to measure blood flow information of the measured part based on the optical signal. The controller estimates a sleep state of the user based on the blood flow information and controls, based on the sleep state, a sound wave outputted from the speaker.Type: ApplicationFiled: December 27, 2018Publication date: November 12, 2020Inventor: Takahiro WATANABE
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Publication number: 20200352458Abstract: The present invention relates to a device and a method for detecting a peak of an intracranial pressure (ICP) waveform using a morphological feature of an arterial blood pressure waveform.Type: ApplicationFiled: July 24, 2020Publication date: November 12, 2020Applicant: Korea University Research and Business FoundationInventor: Dong-Joo Kim
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Publication number: 20200352459Abstract: Wearable thermoelectric devices are provided for spatial and temporal cooling/heating on multiple spots of a wearer's skin. The devices include multiple thermoelectric units supported by a flexible band as an array. A control circuit provides switch signals to selectively and sequentially turn on and turn off the thermoelectric units.Type: ApplicationFiled: August 9, 2018Publication date: November 12, 2020Inventor: Jae Yong Lee
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Publication number: 20200352460Abstract: A pixel circuit includes a sensing block, a stimulation block, a first line control circuit, and a second line control circuit. The sensing block outputs biometric data of a biosignal in response to a first selection signal. The stimulation block radiates a stimulation signal in response to a second selection signal. The first line control circuit outputs the first selection signal for selecting the sensing block as a target sensing block, and outputs the second selection signal for selecting the stimulation block as a target stimulation block. The second line control circuit processes characteristic data associated with the biometric data and the stimulation signal.Type: ApplicationFiled: April 20, 2020Publication date: November 12, 2020Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTEInventors: CHUNWON BYUN, O Eun KWON, Chan Woo PARK, Hyunkoo LEE, Sukyung CHOI, Chan-mo KANG, Byoung-Hwa KWON, Chil Seong AH, Hyunsu CHO, JEONG IK LEE, Nam Sung CHO
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Publication number: 20200352461Abstract: Conventionally, Atrial Fibrillation (AF) has been detected using atrial analyses which is vulnerable to background noise. Again there is a dependency on statistical features which are extracted from R-R intervals of long ECG recordings. The present disclosure addresses AF detection from single lead short ECG recordings of less than one minute wherein automatic detection of P-R and P-Q intervals is difficult, which introduces error in feature computing from the segregated intervals and compromises the performance of the classifier. In the present disclosure, a Recurrent Neural Network (RNN) based architecture comprising two Long Short Term Memory (LSTM) networks is provided for temporal analysis of R-R intervals and P wave regions in an ECG signal respectively. Output sates of the two LSTM networks are merged at a dense layer along with a set of hand-crafted statistical features to create a composite feature set for classification of the AF.Type: ApplicationFiled: March 24, 2020Publication date: November 12, 2020Applicant: Tata Consultancy Services LimitedInventors: Rohan BANERJEE, Avik GHOSE, Sundeep KHANDELWAL
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Publication number: 20200352462Abstract: Techniques are disclosed for explaining and visualizing an output of a machine learning system that detects cardiac arrhythmia in a patient. In one example, a computing device receives cardiac electrogram data sensed by a medical device. The computing device applies a machine learning model, trained using cardiac electrogram data for a plurality of patients, to the received cardiac electrogram data to determine, based on the machine learning model, that an episode of arrhythmia has occurred in the patient and a level of confidence in the determination that the episode of arrhythmia has occurred in the patient. In response to determining that the level of confidence is greater than a predetermined threshold, the computing device displays, to a user, a portion of the cardiac electrogram data, an indication that the episode of arrhythmia has occurred, and an indication of the level of confidence that the episode of arrhythmia has occurred.Type: ApplicationFiled: April 16, 2020Publication date: November 12, 2020Inventors: Lindsay A. Pedalty, Niranjan Chakravarthy, Rodolphe Katra, Tarek D. Haddad, Andrew Radtke, Siddharth Dani, Donald R. Musgrove
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Publication number: 20200352463Abstract: A method of constructing a value representative of an interaction between a plurality of brain regions. The method is implemented by an electronic device, which includes a processor and a memory. The method includes: obtaining, in the form of connectivity matrices, dynamic functional networks, which are representative of electrical signals measured for a predetermined number of points of interest, called nodes, within a cerebral cortex during a given time period; determining, from at least one of said connectivity matrices, a global efficiency score and at least one clustering coefficient score for each node of said at least one of said connectivity matrices; and calculating a value representative of an interaction between the plurality of brain networks in the form of a distribution ratio using said global efficiency score and said clustering coefficient scores.Type: ApplicationFiled: February 1, 2019Publication date: November 12, 2020Inventors: Mahmound Hassan, Fabrice Wendling, Aya Kabbara
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Publication number: 20200352464Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for synchronizing neuroelectric measurements with diagnostic content presentation by performing actions that include causing a presentation system to present diagnostic content a user, where the diagnostic content includes: a first content frame prompting the user to perform a physical task, a second content frame including electroencephalogram (EEG) synchronization content, the second content frame sequentially following the first content frame, and a third content frame indicating an outcome of the physical task, the third content frame sequentially following the second content frame. The actions include obtaining, from a brainwave sensor, EEG signals of the user during presentation of the diagnostic content. The actions include providing the EEG signals as input features to a machine learning model that is trained to predict a psychological state of the user based on the EEG signals.Type: ApplicationFiled: May 11, 2020Publication date: November 12, 2020Inventors: Sarah Ann Laszlo, Nina Thigpen, Vladimir Miskovic, Yvonne Yip
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Publication number: 20200352465Abstract: Systems and methods for recording bipolar electrogram signals by dynamically selecting electrode pairs. For a particular electrode of interest, a reference electrode is identified as the physically closest electrode to the electrode of interest that satisfies at least one selection criterion indicative of an absence of concurrent electrical activation.Type: ApplicationFiled: May 5, 2020Publication date: November 12, 2020Inventor: Stephen Gaeta
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Publication number: 20200352466Abstract: Techniques are disclosed for using both feature delineation and machine learning to detect cardiac arrhythmia. A computing device receives cardiac electrogram data of a patient sensed by a medical device. The computing device obtains, via feature-based delineation of the cardiac electrogram data, a first classification of arrhythmia in the patient. The computing device applies a machine learning model to the received cardiac electrogram data to obtain a second classification of arrhythmia in the patient. As one example, the computing device uses the first and second classifications to determine whether an episode of arrhythmia has occurred in the patient. As another example, the computing device uses the second classification to verify the first classification of arrhythmia in the patient. The computing device outputs a report indicating that the episode of arrhythmia has occurred and one or more cardiac features that coincide with the episode of arrhythmia.Type: ApplicationFiled: April 16, 2020Publication date: November 12, 2020Inventors: Niranjan Chakravarthy, Siddharth Dani, Tarek D. Haddad, Donald R. Musgrove, Andrew Radtke, Eduardo N. Warman, Rodolphe Katra, Lindsay A. Pedalty
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Publication number: 20200352467Abstract: A system for cardiac monitoring and therapy includes a mother device configured to receive signals indicative of cardiac electrical activity in a patient's heart. The mother device includes a mother wireless communications module configured to transmit and receive information to and from the mother device. The system also includes a satellite device configured to receive the signals indicative of the cardiac electrical activity in the patient's heart from a remote location relative to the mother device and includes a satellite wireless communications module configured to transmit from and receive communications sent to the satellite device to at least communicate with the mother wireless communications module. The system also includes a processor configured to receive the signals indicative of the cardiac electrical activity in the heart received by the mother device and the satellite device and, based thereon, control delivery of electrical therapy to the patient's heart.Type: ApplicationFiled: July 29, 2020Publication date: November 12, 2020Applicant: The Brigham and Women's Hospital, Inc.Inventor: Michael O. Sweeney
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Publication number: 20200352468Abstract: The present invention relates to a system and methods generally aimed at surgery. More particularly, the present invention is directed at a system and related methods for performing surgical procedures and assessments involving the use of neurophysiology.Type: ApplicationFiled: July 22, 2020Publication date: November 12, 2020Inventors: Kevin Runey, Allen Farquhar, James Gharib, Albert Pothier, Sean Parker
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Publication number: 20200352469Abstract: In described embodiments, a device and method for diagnosing brain and neurological issues is provided. The device measures the performance of Convergence, Divergence, and binocular tracking capabilities of a subject's eyes, which can be used to determine whether a subject has experienced a brain or other neurological event.Type: ApplicationFiled: July 23, 2020Publication date: November 12, 2020Inventor: Mansour Zarreii
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Publication number: 20200352470Abstract: Systems and methods may monitor electrical activity of a patient's heart using electrodes during delivery of cardiac therapy and determine a degree of posterior left bundle branch engagement based on the monitored electrical activity. The systems and methods may adjust the cardiac therapy based on the degree of posterior left bundle branch engagement.Type: ApplicationFiled: March 11, 2020Publication date: November 12, 2020Inventor: Subham Ghosh
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Publication number: 20200352471Abstract: A signal measuring apparatus and method is provided. The signal measuring apparatus inputs a reduced voltage signal to an input end of an amplifier by resetting a voltage signal, which is acquired by applying a known current signal to a target object, using a common mode voltage at least once during one period of a current signal. The signal measuring apparatus acquires a digital signal corresponding to an object impedance change by converting an output of the amplifier.Type: ApplicationFiled: October 17, 2019Publication date: November 12, 2020Applicant: Samsung Electronics Co., Ltd.Inventor: JongPal KIM
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Publication number: 20200352472Abstract: The invention relates to medicine, particularly to agents for magnetic resonance diagnostics for oncological diseases. Developed for this purpose are a diagnostic preparation and a diagnostic method based on using said diagnostic preparation, in which a deuterated derivative of 2-amino-2-methylpropionic acid or 2-(N-methylamino)-2-methylpropionic acid and/or a pharmaceutically acceptable salt thereof, or a mixture of at least two deuterated derivatives of 2-amino-2-methylpropionic acid and/or 2-(N-methylamino)-2-methylpropionic acid and/or the pharmaceutically acceptable salt thereof is used as said preparation. The method according to the invention includes conducting magnetic resonance imaging and/or magnetic resonance spectroscopy on deuterium nuclei at a time after administration of the diagnostic preparation sufficient for the diagnostic preparation to accumulate in the tumor tissue of a subject in order to produce a magnetic resonance image and/or a magnetic resonance spectrum accordingly.Type: ApplicationFiled: November 21, 2017Publication date: November 12, 2020Applicant: SOLVEX LIMITED LIABILITY COMPANY [RU/RU]Inventors: Aleksei Valerievich LESIV, Pavel Evgenievich IVASHKIN, Mikhail Vladimirovich GULYAEV, Evgeniya Olegovna DOROFEEVA, Aleksei Viktorovich KOSENKOV, Mikhail Valentinovich KISELEVSKY, Vladimir Ivanovich POLSHAKOV
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Publication number: 20200352473Abstract: Provided herein are systems, devices, and methods to facilitate imaging an infant using a magnetic resonance imaging (MRI) device. A system for facilitating imaging an infant using an MRI device is provided herein, the system comprising a radio frequency (RF) coil assembly configured to be coupled to the MRI device and comprising a first RF coil configured to transmit RF signals during MRI and/or be responsive to MR signals generated during MRI and a helmet for supporting at least a portion of the infant's head, and an infant support to support at least a portion of the infant's body and configured to be coupled to the RF coil assembly. Further provided is an apparatus for coupling an infant support to an MRI device.Type: ApplicationFiled: May 1, 2020Publication date: November 12, 2020Inventors: Gang Chen, Anne Michele Nelson, Jacob Coumans, Eddy B. Boskamp
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Publication number: 20200352474Abstract: The present document describes a flow measuring apparatus for measuring a flow through a section of an inhalation apparatus, comprising at least one set of Pitot tubes first a second Pitot tube and streamlinings extending longitudinally parallel to the Pitot tubes and the set of Pitot tubes is configured for traversing entirely a lumen which define the section of the inhalation apparatus and are respectively fluidly connected to a differential pressure sensor for measuring a difference between a stagnation pressure and a static pressure within the flow measuring apparatus.Type: ApplicationFiled: November 15, 2018Publication date: November 12, 2020Inventors: Thierry PORÉE, Edouard CURRAN