Abstract: A photoplesythmography (PPG) device includes an array of light emitting diodes (LED's) arranged to illuminate a tissue sample, and an array of photodetectors (PD's) adapted to detect light returned from the tissue sample and to output a PD output signal which depends at least in part on a bias current. The PPG device also includes a compensation current source and a controller. The controller is adapted to operate the compensation current source so that the current source outputs the bias current to the photodetector array.

Abstract: A light-to-digital converter (2) comprises a light-to-current converter (10); a current integrator (4) with an integrator output (30) resettable to a baseline level; and a counter (18) with a digital output (26), wherein the light-to-current converter (10) is switchably connectable as a positive integration input to the current integrator (4), for, during a light-collecting phase (404-406), integrating a current from the light-to-current converter (10), the integrator output (30) starting from the baseline value and ending at a value to be digitized; a reference current source (14) is switchably connectable as a negative integration input to the current integrator (4), for, during a counting phase (406-408) subsequent to the light-collecting phase (404-406), integrating a reference current from the reference current source (14), the integrator output (30) starting from the value to be digitized and ending at the baseline value, the time spent integrating the reference current corresponding to the value to be

Abstract: A method for diagnosing gastro esophageal reflux disease (GERD), comprising: introducing an endoscope into a stomach of a subject; measuring a pressure in the stomach while supplying gas into the stomach using the endoscope; and determining whether the subject has GERD or not based on a maximum value of the pressure and a wave pattern of a value of the pressure.

Abstract: Provided are a nanofiber mesh bioelectrode including: a nanofiber mesh sheet in which nanofibers containing a biocompatible water-soluble polymer are entangled in a network form; and a conductive layer coated on the nanofiber mesh sheet and including a conductive material, and a method of producing the same. The nanofiber mesh bioelectrode according to the present invention does not cause discomfort when applied to a living body due to its excellent biocompatibility and excellent flexibility, and easily measures a biosignal or easily applies stimulation for a long period of time, as the nanofiber mesh bioelectrode is not easily detached.

Abstract: A method of planning a patient-specific cardiac procedure according to an embodiment of the current invention includes receiving three-dimensional imaging data of a patient's heart, simulating at least one of electrophysiological or electromechanical activity of at least a portion of the patient's heart using the three-dimensional imaging data, and planning the patient-specific cardiac procedure based on the simulating. The cardiac procedure is for providing a preselected alteration of at least one of electrophysiological or electromechanical behavior of the patient's heart.

Abstract: An electrocardiogram measurement system includes a patch-type electrocardiogram measurement apparatus; a first device connected to the electrocardiogram measurement apparatus by means of a first communication and configured to store electrocardiogram data measured by the electrocardiogram measurement apparatus; and a second device connected to the electrocardiogram measurement apparatus by means of the first communication and configured to store electrocardiogram data measured by the electrocardiogram measurement apparatus. The electrocardiogram data measured by the electrocardiogram measurement apparatus includes measured time information.

Abstract: A method includes receiving, in a processor, a two-dimensional (2D) electroanatomical (EA) map of an interior surface of at least a portion of a cavity of an organ of a patient, the 2D EA map including electrophysiological (EP) values measured at respective locations on the interior surface. A complex analytic function is fitted to a set of the EP values that were measured in a given region of the 2D EA map. A singularity is identified in the fitted complex analytic function. The region is projected onto a three-dimensional (3D) EA map of the interior surface. At least part of the 3D E A map is presented to a user, including indicating an arrhythmogenic EP activity at a location on the 3D E A map corresponding to the singularity identified in the fitted complex analytic function.

Abstract: Systems and methods for classifying a cardiac arrhythmia are discussed. An exemplary system includes a correlator circuit to generate autocorrelation sequences using information of cardiac activity of a subject, including signal segments taken from a cardiac signal at respective elapsed time with respect to reference time. The correlator circuit can generate a correlation image using the autocorrelation sequences. The correlation image may be constructed by stacking the autocorrelation sequences according to the elapsed time of signal segments. An arrhythmia classifier circuit can classify the cardiac activity of the subject as one of arrhythmia types using the correlation image.

Abstract: A heartbeat analyzing method and a heartbeat analyzing system are provided. The heartbeat analyzing method includes: sensing a user using a wearable device and acquiring a physiological signal record; performing a dispersion calculation to the physiological signal record using the wearable device and generating a Poincaré plot of the physiological signal record; and inputting the Poincaré plot into a heart rhythm classifier model and determining a heartbeat classification of the user based on personal health data of the user.

Abstract: In one embodiment, a brain signal tracking system includes a probe to be inserted into brain blood vessels, and including an electrode, a signal generator to generate a calibration signal to be emitted by the electrode at different locations in the blood vessels, a tracking subsystem to track locations of the electrode, head surface electrodes to be applied to a head, head surface electrodes configured to detect the calibration signal at respective amplitude values, with a distribution of the respective amplitude values over the head surface electrodes being indicative of a corresponding one of the tracked locations from which the calibration signal was emitted by the electrode, and processing circuitry to find a function to compute a source location in the brain of a brain signal responsively to the distribution of the respective amplitude values of the calibration signal over the head surface electrodes for ones of the tracked locations.

Abstract: This invention relates to a universal ECG monitor of cardiac signals with enhances possibilities of scanning. The prior art monitors of cardiac signals make possible either a short-time touching by fingers or by other part of the human body of the electrodes, or they are permanently for a long time by means of a chest belt or by other means attached to the human body, wherein, such means are impractical and non-emergency. The equipment according to the present invention is a universal ECG monitor of a compact and easily portable design, which monitor substitutes the prior art costly and with difficulty movable hospital equipment. Moreover, it is a very economical solution, which makes possible to obtain a complete set ECG curves, i.e. the 12-lead ECG, by means of one of the monitor subsequently moved into various positions, and so to scan signals from different parts of the human body.

Abstract: It is presented a method for obtaining data for an Electrocardiogram, ECG, using a portable sensor device comprising two electrodes. The method comprising the steps of: receiving a trigger to obtain measurements for the ECG; setting at least one switch in a conducting state to close a connection between the two electrodes; setting the at least one switch in a blocking state to conductively separate the two electrodes; and capturing measurements for the ECG using the at least two electrodes.

Abstract: A method of registering a luminal network to a 3D model of the luminal network with real-time feedback is disclosed, including generating the 3D model of the luminal network based on images of the luminal network, generating an electromagnetic field about the luminal network, inserting a location sensor into the electromagnetic field, tracking the location of the sensor within the luminal network, comparing the tracked locations of the sensor with sensors located outside of the luminal network and the portions of the 3D model representative of open space, and presenting on a user interface an indication of which portions of the luminal network have been sufficiently traversed by the sensor to register that portion of the luminal network to the 3D model.

Abstract: A method is disclosed for foot sensors to be used to determine at least two characteristics of a subject's activity by using a combination of sensors for force and foot orientation/motion/position. A wearable footwear ecosystem is comprised of the subject's footwear, sensor-enabled insoles or insertable devices, in- or on-footwear electronics that is hard wired to the sensors and may contain additional sensors such as accelerometers, a master device and means to communicate (typically wirelessly) among the various sensor platforms, and the master device including clock synchronization. Correlating the time stamps for data among various sensors, and the master device communicating wirelessly is critical to accurate determination of the desired characteristics. Multiple force-sensitive resistors on a common substrate are individually optimized for dynamic range. Pulse sensors using arrays of such force-sensitive resistors are implemented.

Abstract: Provided is a system, method, and apparatus for tracking a body. The method includes communicating at least one activation signal to each RF transponder of a first array and a second array, receiving a plurality of response signals from the first array and the second array, the plurality of response signals comprising a response signal for each RF transponder of the first array and the second array, determining a difference in distances between the antenna and each RF transponder of the first array and each transponder of the second array based at least partially on at least one corresponding response signal of the plurality of response signals, and determining a relative location of the first portion of the body and the second portion of the body.

Abstract: A mask size gauge for selecting a size of a mask in accordance with a distance in a height direction between an upper reference part in an upper portion of a face of a wearer, and a lower reference part in a lower portion, includes: a reference position indicating portion indicating that the reference position indicating portion is to be placed at a height position of the upper reference part on an outer lateral side of an eye of the wearer; and a size indicating portion that is located at a position which is closer to a middle of the face than the reference position indicating portion, and that indicates the size of the mask according to a height position of the lower reference part.

Abstract: A method for operating an accessory device to capture calibration data. The method can include capturing an image of a portion of a user's body that includes the user's stoma and at least two reference locations, and storing distance scale information representative of a distance between the two reference locations. The method further includes processing the captured image, including: identifying the reference locations, identifying the stoma, and generating calibration data representative of one or more stoma parameters as a function of the identified reference locations, identified stoma and the distance scale information. The calibration data can be stored.

Abstract: Systems and methods for identifying abnormal movements or tremors in one or more human subjects. Kinetic and/or electromyographic sensors are employed in detection hardware to detect voluntary and involuntary movements. The data collected from such voluntary and involuntary movement detection can be further processed and compared to baseline data to identify and distinguish abnormal movements from normal movements. The identification of abnormal movements may indicate a neurodegenerative disorder.

Abstract: A gait analysis system, which includes a neural network with a recurrent neural network layer and a fully connected layer, that receives sensor data indicative of an individual's gait and outputs an assessment regarding the individual's health. The neural network is trained using training data indicative of abnormal gaits and normal gaits. To analyze the training data and the sensor data, the recurrent neural network layer parses each piece of data into a series of windows and analyzes each window in series to generate a context vector characterizing each window and the previously analyzed windows. The fully connected layer, having been trained to differentiate between normal gaits and abnormal gaits based on context vectors characterizing the training data, is used to generate a final assessment characterizing the user gate as normal or abnormal using one or more of the context vectors characterizing the sensor data.

Abstract: A method of monitoring respiration with an acoustic measurement device, the acoustic measurement device having a sound transducer, the sound transducer configured to measure sound associated with airflow through a mammalian trachea, the method includes correlating the measured sound into a measurement of tidal volume and generating at least one from the group consisting of an alert and an alarm if the measured tidal volume falls outside of a predetermined range.

Abstract: A lower limb muscle strength evaluation device acquires an angle of at least one of left and right lower limbs of a user while the user stands up from a sitting state, detects at least one lower limb parameter from among a first lower limb maximum value indicating the angle when the lower limb is initially inclined the most in a first direction, a lower limb minimum value indicating the angle when the lower limb is inclined the most in a second direction, a second lower limb maximum value indicating the angle when the lower limb is again inclined the most in the first direction, a first lower limb elapsed time, a second lower limb elapsed time, and a third lower limb elapsed time, evaluates a lower limb muscle strength of the user using the at least one lower limb parameter, and outputs an evaluation result.

Abstract: An information processing apparatus includes a processor, in communication with a memory, executing a process including acquiring identification information of a wireless device and information for identifying a position of the wireless device; storing a learned model generated by performing machine learning by using a training dataset including a position of a person to which the wireless device is attached and a movement destination of the person to which the wireless device is attached; inferring the movement destination of the person to which the wireless device is attached from the position of the wireless device, based on the learned model; and reporting the inferred movement destination.

Abstract: The disclosure proposes an electronic device and a method performed in the electronic device for collecting a sensor data from live at least one sensor device, obtaining a first sensor data of the sensor data representing a first primary body behaviour pattern of the person, obtaining a second sensor data of the sensor data representing a second primary body behaviour pattern of the person, the second primary body behaviour pattern is associated with the first primary body behaviour pattern of the person and determining a sensor data difference by comparing the first sensor data with the second sensor data followed by determining a health score value based on the determined sensor data difference.

Abstract: Systems and apparatus related to adaptive support garments including adaptive support structures, lacing systems, and an adaptive engine are discussed. In an example, an adaptive support apparel system includes an activity sensor, an adaptive support garment, and a control circuit. The activity sensor monitors activity of a user. The adaptive support garment includes an integrated adaptive support system coupled to the adaptive engine to automatically adjust a portion of the adaptive support garment through manipulation of the adaptive support system. The control circuit configured to send commands to the adaptive engine in response to input received from the activity sensor.

Abstract: A behavior determination device includes a measurement data receiving device configured to acquires measurement data indicating a pressure or a force measured by one or a plurality of sensors provided on a sole surface of a user's foot, a data analyzing device configured to analyze the measurement data, to identify one load phase in which the user makes one step, and calculate a plantar pressure parameter and a time parameter for every one load phase, and a behavior determining device configured to detect a peak point where a maximum local maximum is obtained for every predetermined time, based on the plantar pressure parameter and the time parameter, and determine a behavior of the user based on the peak point.

Abstract: A device for determining the frequency of a dominant tone of a tinnitus perceived by a patient. A tone generator plays tones, an input unit receives patient evaluations, and a controller carries out a similarity measurement and a comparison of pairs of tones. The controller controls the tone generator for the similarity measurement to generate successive tones, and, after playing a respective tone, receive patient's evaluation regarding the similarity of the tone to the dominant tone of the tinnitus. The controller also controls the tone generator for the comparison of pairs of tones to play successive pairs of tones, and, after playing a respective pair, receives the patient's evaluation as to which tone of the pair is more similar to the at least one dominant tone of the tinnitus. Using the results, the frequency most similar to the frequency of the dominant tone of the tinnitus can be determined.

Abstract: This document provides methods and materials involved in assessing concentrations of analytes in an environment using a diamond-containing carbon electrode. For example, methods and materials for using FSCV or paired pulse voltammetry to discriminate analytes based on their adsorption characteristics to a diamond-containing carbon electrode are described herein.

Abstract: Systems and methods are provided for determining levels of an analyte in a biological fluid sample. A transdermal sampling and analysis device may include a substrate, at least one disruptor mounted on the substrate, a reservoir configured to collect and contain a biological fluid sample; a sensing element comprising at least two sensing electrodes, and at least one layer of a cofactor covering the sensing element in which the cofactor catalyzes a reaction to determine levels of an analyte in the biological fluid sample. The at least one disruptor of the transdermal sampling and analysis device may generate a localized heat capable of altering permeability characteristics of a stratum corneum layer of skin of an organism. The surface of at least one of the sensing electrodes of the transdermal sampling and analysis device may be coated with a sensing layer in which an enzyme immobilized within a hydrogel.

Abstract: A sensor (e.g., an optical sensor) that may be implanted within a living animal (e.g., a human) and may be used to measure an analyte (e.g., glucose or oxygen) in a medium (e.g., interstitial fluid, blood, or intraperitoneal fluid) within the animal. The sensor may include a sensor housing, an analyte indicator covering at least a portion of the sensor housing, and a drug eluting material having tailored elution properties that contains a drug that reduces deterioration of the analyte indicator, wherein the drug eluting material is incorporated in and/or in close proximity to the analyte indicator, and the drug eluting material is configured to release the drug according to a tailored elution profile.

Abstract: The present disclosure provides a system and method for analyzing a physiological parameter of a vital sign signal. The method may include acquiring a vital sign signal, storing data, computing and analyzing, processing, and outputting a result. The system may compute and analyze the physiological parameter of the vital sign signal, especially a blood oxygen saturation, via a plurality of algorithms, judge or process the computation result, and output the judgment result.

Abstract: A reflective PPG sensor, in which motion artifacts have a reduced effect, is configured to be placed on one of a forehead, a finger or a wrist of a subject on a location selected according to a predetermined range of a signal quality index and has a force per unit area between 0.3 N/cm2 and 1.5 N/cm2, and a bonding pressure, for sensor to skin adhesion, between 10 N/cm2 and 20 N/cm2. In one instance, the reflective PPG sensor of these teachings also has a weight between 6 g and 12 g.

Abstract: A biosensing device includes a sensor module and an electric signal transducer. The sensor module includes a biosensor adapted for measuring a biosignal of a host, and a fixed seat including a conducting member that is electrically connected to the biosensor. The electric signal transducer is for receiving and sending the biosignal measured by the biosensor, is coupled to the sensor module, and includes an electric signal unit electrically connected to the conducting member, and a battery connected to the electric signal unit. The electric signal unit has two electrical contacts that cooperatively define a switch. The battery provides power supply to the biosensor when the electric signal transducer is coupled to the sensor module.

Abstract: A biointerface membrane for an implantable device including a nonresorbable solid portion with a plurality of interconnected cavities therein adapted to support tissue ingrowth in vivo, and a bioactive agent incorporated into the biointerface membrane and adapted to modify the tissue response is provided. The bioactive agents can be chosen to induce vascularization and/or prevent barrier cell layer formation in vivo, and are advantageous when used with implantable devices wherein solutes are transported across the device-tissue interface.

Abstract: A displacement-generating battery cell for driving a drug-delivery device is described. The cell may include at least one volume-changing element. The cell may include a housing formed according to a concertina-shaped design with folds in the walls thereof and may contain an internal chemical reaction system. The chemical reaction system may include an electrode. The electrode may be the volume-changing element. The arrangement of said chemical reaction system may be such that an expansion of the volume-changing element in a direction lengthens the cell and thus reduces the extent of the folds. Drug-delivery devices including the displacement-generating battery cell are also described.

Abstract: This disclosure provides equipment and processes for blood glucose management. Embodiments may comprise a lancet device that includes a base that supports a lancet and a cover. The cover can move controllably from an un-depressed position to a depressed position when a predetermined force is applied. The cover can provide access to the lancet in the depressed position. In another aspect, a biological test kit may include a reusable module and a disposable module. The disposable module may include one or more lancet devices such as that described above to collect a biological sample, one or more strip stations supporting biological strips and a disposable module connector. The reusable module may support measuring equipment to measure a property of the biological sample and a reusable module connector that engages removably with the disposable module connector.

Abstract: An independent blood filter device depends on flow geometry to deliver blood serum or plasma free of detrimental levels of hemoglobin. It depends critically on an upstream flow rate or pressure differential limiting control element or device that limits the rate of change of pressure differential across the filter element. Pre-evacuated versions can be used to simultaneously draw blood from a living being and provide pressure differential across the filter element between an evacuated collector and a supply end open to atmosphere. A unit pressurized by hand motion employs the external shape of a partially filled blood collection tube as a piston to produce pressure in advance of the control element or device to create the pressure differential across the filter element to a collector vented to atmosphere. The control element or device is disclosed in numerous forms, including specially sized flow constrictions and compliant arrangements.

Abstract: The present disclosure provides a method for detecting female urination by using a wearable device. A female urination detection method according to an embodiment of the present disclosure is a method for detecting urination of a subject to be measured, who is a female, by using a measurement device mounted on the subject to be measured, the method comprising: (a) acquiring sensor data (S) generated according to movement of a sensor of the measurement device; and (b) extracting effective data (SEff) related to urination by filtering the sensor data (S) acquired in (a) by an effective data extracting module of an analysis device through a preset method.

Abstract: The invention relates to a method for quantifying the balance of an individual to obtain a value representative of the balance of said individual, said method being implemented by a device comprising at least one data processing module, one storage means, and one classification module, said method comprising in particular the following steps: segmenting, as a function of time, the statokinesigram(s) of an individual so as to generate several statokinesigram portions, extracting, from the statokinesigram portions, values of at least one trajectory parameter, determining the value of at least two quantifiers, from the values of trajectory parameters extracted in the extraction step for each of the statokinesigram portions generated in the segmentation step, and determining said value representative of the balance of the individual from the values of the quantifiers of each of the statokinesigram portions.

Abstract: The present disclosure relates to a method and a system for quantifying a biomarker of a biological tissue. Two spectral sub-intervals are determined from a plurality of images of the tissue acquired at discrete wavelengths within a main wavelength interval using an imaging sensor in a manner such that the combination of the image data in the at least two spectral sub-intervals are correlated with a clinical variable of interest. The tissue is illuminated using one or more light sources with wavelengths within the at least two spectral sub-intervals. A measurement is of the light reflected by the tissue is acquired using an imaging sensor; and a measure of the biomarker of the tissue is calculated using the acquired measurement. The main wavelength interval is broader than each of the at least two spectral sub-intervals and at least one spectral confounder causing a spectral variability of the acquired image is present in the tissue.

Abstract: The present relates to a computer-implemented method for detecting and predicting cognitive pathologies of the brain based on a “Hold” and “Release” process. The invention also concerns a device related to the claims method.

Abstract: In some aspects, a sensor includes an optical transmitter that transmits to a brain of a person infrared radiation, and an acoustic receiver that detects an ultrasound signal generated in the brain in response to the infrared radiation. A processor determines oxygen saturation of the brain based on the detected ultrasound signal. The sensor may be included in a cap worn by the person, implanted under the skin of the person, or inserted through the nasal canal of the person.

Abstract: A wearable system for epileptic seizure detection, comprising an eyeglasses frame, with a left arm and a right arm configured to rest over the ears of an intended person wearing the eyeglasses, a first pair of electrodes located in the left arm, and a second pair of electrodes located in the right arm, the first pair of electrodes and the second pair of electrodes arranged such to be in contact with the skull of the intended person wearing the eyeglasses, and an EEG signal acquiring system integral to the left and right arms, connected to measuring outputs of the respective first pair and second pair of electrodes.

Abstract: Methods, systems, and apparatus for detecting and/or validating a detection of a state change by matching the shape of one or more of an cardiac data series, a heart rate variability data series, or at least a portion of a heart beat complex, derived from cardiac data, to an appropriate template.

Abstract: According to an embodiment, an electronic device includes a camera, and at least one processor configured to: determine, from an image including a face of a user obtained via the camera, skin information indicating a skin condition of the user, generate control information for controlling a skin-care device to perform care based on the determined skin information and information regarding the skin-care device, and provide the control information to the skin-care device.

Abstract: A method for facilitating a sleep session is provided. The method comprises provisioning a virtual reality device with at least one sleep program configured to provide an immersive experience to facilitate a sleep session for a user; determining recommended sleep settings for the sleep program; configuring the sleep program with at least some of the recommended sleep settings; running the sleep program; and tracking sleep information for the user associated with the sleep session.

Abstract: Systems, methods, devices, and apparatus for monitoring intra-oral physiologic and biologic data related to sleep performance for patients with obstructive sleep apnea (OSA). In embodiments, the monitor collects data within the mouth of the patient and sends this data to a smart phone running a dedicated APP which in turn sends this data to the computer of the health care worker for evaluation. In embodiments, data collected is processed using a distributed processing arrangement and an integral scoring algorithm to produce parameters key to the diagnosis and/or monitoring of patients with OSA.

Abstract: This system for identifying information represented by biological signals is configured so as to detect biological signals (S501), analyze the detected biological signals and then output feature data (S502), determine the respective similarities between the feature data and a plurality of teaching data (S503), store the similarities per time in a time series (S504), and determine information represented by the biological signals on the basis of the plurality of similarities within a prescribed period among the stored similarities in the time series (S505).

Abstract: In some aspects, a closed-loop system for monitoring and/or treating brain function of a person includes a CMUT device that transmits ultrasound radiation to the brain of the person and receives and detects an ultrasound signal generated in the brain, and a processor that assesses the received ultrasound signal to determine brain function and controls further transmission of ultrasound radiation from the CMUT device based on the determined brain function.

Abstract: A method for providing an image of a subject by utilizing an array of transmission elements in a thermoacoustic imaging apparatus.

Abstract: An hydrothermal sensing device wherein the hydrothermal sensing device comprises at least one layer wherein the at least one layer is a reflective layer, a mesh layer, a semi-rigid layer and a wicking layer wherein the reflective layer can be attached to the mesh layer, and the mesh layer can be attached to the semi-rigid layer and the wicking layer can be removably attached to the semi-rigid layer. The semi-rigid layer can further comprise a band wherein the band can comprise a printed circuit board having at least one sensing module, a microcontroller, a communications module, and power source. The reflective layer is porous and UV resistant.