Abstract: A clamping assembly for adjustably connecting a device to a rail, including a clamp body, rail interface mechanism, and support mechanism for the device. The rail interface mechanism attaches to rails of various heights and thicknesses with a single user control activation. The rail interface mechanism includes at least one flanged fixed upper jaw, a rail clamp control comprised of a threaded vertical axle terminating in a pm end, a flanged lower jaw constrained to slidable vertical motion along an internal face of the clamp body by the pin end of the vertical axle, and two angled wedges that can be extended and retracted horizontally.

Abstract: A device and a method of making and using the device for preventing sedimentation of airborne particles on a surface. The device includes a pad comprising with top surface, where openings are formed in the top surface, where a plurality of nozzle is situated in the openings such that a portion of the nozzle is an outlet for directing a stream of gas in an essentially perpendicular direction away from the top surface. The device also includes a hose connected to the nozzle such that the hose supplies the nozzles in the pad with the gas and a conditioning source that brings the gas into the hose after cleaning it. The flow requirements are automatically adjusted by the system (e.g., based on characteristics of the particle load).

Abstract: An extremity support system comprising a board having an upper surface that supports a resilient member. The board has a curved portion that facilitates it to pivot when connected to a table or bed. It also has a plurality of openings for holding a plurality of straps that can be positioned over the resilient member. The resilient member also includes a rounded end for facilitating the board to pivot; and a top furrow that supports and provides access to an extremity extending off the surface of the table or bed of a patient laying in a plurality of positions. In addition, the straps have methods of placement to function as non-occlusive non-obstructive guardrails that maintain the extremity in the furrow of the resilient member, do not interfere with the ability of the board to pivot, and do not touch the extremity under usual circumstances thereby preventing injuries to an arm or a leg.

Abstract: A patient examination system for locating a patient above a floor. The patient examination system includes a frame assembly, one or more motion-controlling assemblies connected to the frame assembly for moving one or more selected movable portions of the frame assembly, and a patient support assembly that is supported by the frame assembly. The patient support assembly includes a seat subassembly, a back subassembly, a footrest subassembly, and a cover element covering a seat cushion and a footrest cushion in the footrest subassembly. The cover element has an exposed surface formed for engagement with the patient. The seat subassembly supports the seat cushion and is secured to the upper element of the frame assembly. The frame assembly is configured to support the seat subassembly relative to the floor in a lowered position thereof, in a raised position thereof, in intermediate seat positions therebetween, and in Trendelenburg positions.

Abstract: A method and apparatus for helping a user walk may verify whether the user is in a standing state and calculate a torque that controls balance of the user, and an assistance force for controlling balance may be provided for the user based on the torque generated by an actuator.

Abstract: A gait state determination apparatus includes: a foot attachment structure disposed in the walking assistance apparatus, the foot attachment structure to be attached to a foot of a user; a pressure detection device, disposed in the foot attachment structure, detecting a pressure exerted on a sole of the user; a pressure center calculation device successively calculating a center position of a pressure exerted on the sole during a gait motion of the user based on the pressure exerted on the sole detected by the pressure detection device; and motion determination device determining that it is a timing of a start of forward swinging of the leg to which the walking assistance apparatus is attached when the center position of the pressure calculated by the pressure center calculation devices is shifted from a position in a heel region of the sole to a toe region thereof, is disclosed.

Abstract: An embodiment of a system for treating sleep apnea includes a collar, pump, motor, sensor, memory, and controller, which is configured to store, in the memory, information related to sleep-apnea events or sleep-apnea treatment, experienced by the subject. For example, the controller can obtain, and store in the memory, information related to sleep-apnea events, and the controller, or another computing system, can correlate this information with the subject's lifestyle choices, and can recommend lifestyle changes to improve the subject's sleep apnea. Furthermore, the controller can obtain and store, in the memory, information related to usage and settings of the sleep-apnea system, and the controller, or another computing system, can correlate this information with the subject's wellbeing, and can recommend changes in the usage or the settings of the sleep-apnea system that can improve the subject's wellbeing.

Abstract: An inflation garment for the treatment of DVT is operated by a portable, battery powered air pump and controller detachably mounted on the inflation garment. The controller is formed with hook-fastening devices on the bottom surface of the controller that is detachably engagable with the material on the outer surface of the inflation garment. To mount the controller, the inflation garment is folded to expose the air inlet and outlet ports on the inflation garment to facilitate the operative attachment of the controller ports, then the inflation garment is unfolded and pressed against the bottom surface of the controller to engage the hook fasteners with the material of the inflation garment. A supplemental support is provided to wrap at least partially around the inflation garment to enhance the support of the inflation garment on the patient's limb without slipping.

Abstract: A wearable massager includes a plurality of attachments, each of which is designed for a specific body part. Each attachment includes at least one massaging module on an inner surface that is either formed of mechanical rollers that simulate a massage as they are moved vertically and horizontally, or a plurality of contiguous, inflatable bladders that simulate a massage as they are inflated and rapidly deflated. A controller allows a user to vary the speed and intensity with which the rollers are moved horizontally and vertically, or the level, order and frequency in which each bladder is inflated and deflated. Accordingly, the continuous movement of the rollers or inflation and deflation of the bladders against the wearer's skin simulates the typical movements of a massage therapist's hands and fingers.

Abstract: A stimulation device is provided in accordance with one embodiment. The stimulation device includes a chamber which has a flexible wall portion. A drive unit of the stimulation device is in physical communication with the flexible wall portion so as to cause deflections of the flexible wall portion in opposing directions, thereby resulting in a changing volume of the chamber. The changing volume of the chamber results in modulated positive and negative pressures with respect to a reference pressure. An opening of the stimulation device is for applying the modulated positive and negative pressures to a body part. The stimulation device includes a control device for controlling the drive unit.

Abstract: In some embodiments, a method may include clearing a biological airway. The method may include positioning an inner wearable harness on a torso of a subject. The method may include selectively positioning at least some of a plurality of engines on and/or adjacent at least one treatment area. At least one of the plurality of engines may be releasably couplable to the inner wearable harness. The method may include positioning an outer wearable harness on a torso of a subject. The method may include applying an oscillation force to at least one of the treatment areas using at least some of the plurality of engines. The method may include adjusting the applied oscillation force to the treatment area by activating the outer wearable harness. The method may include mobilizing at least some secretions in an airway within the subject substantially adjacent the at least one treatment area.

Abstract: In some embodiments, a method may include monitoring use of a medical device. The method may include positioning a wearable harness of a medical device on a subject. The method may include selectively positioning at least some of a plurality of engines on and/or adjacent at least one treatment area. The method may include applying an oscillation force to at least one of the treatment areas using at least some of the engines. The method may include mobilizing at least some secretions in an airway within the subject substantially adjacent the treatment areas. The method may include monitoring use of the medical device by the subject using a controller associated with the medical device to determine if the medical device has been used effectively as prescribed.

Abstract: A chest compression device with a chest compression belt assembly including guards and sensors operable with a control system to control operation of the system depending on detection of proper installation of the guards.

Abstract: A pool pump is provided. The pool pump comprises a housing, and a control panel arranged on said housing, with a control unit connected to said control panel to form a capacitive touch control. The housing may be provided with at least one accommodation cavity, the control panel is arranged in a flippable manner at said housing, and the control panel and the end cover are in a horizontal position and at least one preset angle position. The pool pump is detachably connected to a pool pump cover, and the pool pump cover comprises: a cover body; a base connected to said cover body; and at least one functional device arranged on said cover body for implementing at least one of the functions of communication, electrical charging and music play.

Abstract: One or more systems are disclosed for producing microbubbles in a standard tub as well as a pedicure tub for performing pedicures on a user. The one or more systems include a microbubble generating device. The microbubble generating device includes its own housing and is portable or can be attachable to one or more structures such as a pedicure chair. The microbubble generating device includes a pump, an air mixing chamber, a solenoid valve, and electrical timer. After passing through the pump and the air mixing chamber of the microbubble generating device, the outgoing water is infused with microbubbles and redirected from an outlet of the microbubble generating device to the tub or pedicure tub. The system further includes an aerator assembly and one or more filters. Microbubbles are included in the water to provide deep cleaning and other health benefits to the user.

Abstract: Systems and methods are provided for controlling infrared radiation (IR) sources of a sauna including tuning IR wavelength-ranges and radiated power-levels of IR sources, and directing IR to locations on a user's body. In one illustrative embodiment, a sauna may be provided having adjustable IR emitters to emit IR at any wavelength resulting in a desirable radiation treatment for the sauna user. In another illustrative embodiment, a method is provided for tuning IR emitters in a sauna.

Abstract: A cap for a medication container may include: at least one pressure sensor; an air supplying unit; and a controller. The controller may be configured to: receive a first air pressure measurement form inside the medication container, form the at least one pressure sensor; control the air supply unit to supply air at a predetermined pressure for a predetermined amount of time; receive a second air pressure measurement from inside the medication container, form the at least one pressure sensor; and perform an output operation using the first and second air pressure measurements.

Abstract: A reservoir for liquid medicament includes a first boundary portion and a second boundary portion forming at least one cavity to receive the medicament. The first boundary portion is flexible, while the second boundary portion is rigid. At least one of the first and second boundary portions is a transparent boundary portion covered by an opaque cover which is at least partially detachable from the transparent boundary portion.

Abstract: Systems and devices for interfacing between a medicinal vial, a hypodermic needle, and an injection device such as a syringe, comprising a valve, functionally associated with said vial adaptor, said injection device port, and said needle, said valve having a first orientation wherein said injection device port is in fluid flow communication with said vial adaptor and a second orientation wherein said injection device port is in fluid flow communication with said hypodermic needle, wherein rotation of said injection device port between a first position and a second position thereof, drives transition of said valve from said first orientation to said second orientation.

Abstract: A method of dispensing a prescription medication is disclosed. The method may begin with obtaining a medication dispensing system. The system may include a prescription vial and a programmable cap for the prescription vial. The cap may include an outer cover having an exit aperture, an inner cover having an entrance aperture, and a transport portion having a chute. The cap may also include a control system having a processor. The method may include the step of determining, by the processor, that a first waiting period has passed. The control system may then dispense a first portion of the medication. The dispensing may involve sensing that a tablet or capsule of the medication is loaded into the chute and moving, by the control system, the chute of the transport portion out of alignment with the entrance aperture and into alignment with the exit aperture.

Abstract: A product interaction monitor includes sensors for measuring characteristics related to the product and/or product package or other type of container. The product interaction monitor can be installed in a container cap and used to monitor events associated with the container such as product usage. The product interaction monitor can utilize multiple sensor outputs to increase the accuracy of the detection of the events. The product interaction monitor can be used to estimate product inventory or product usage and communicate information regarding the product and/or product usage to a local display or a remote computer.

Abstract: A device for measuring in real time the volume of a partially upturned bottle has a sleeve that extends around the upturned bottle with an open distal end and a closed proximal end. An accelerometer in the device determines the vertical direction and the angle between the vertical direction and the longitudinal axis of the bottle. Another accelerometer measures the force exerted by the bottle in the direction of the longitudinal axis. These parameters are used to calculate the total mass and volume of the upturned bottle. A dimmable screen displays the total mass, total volume, change in mass and/or change in volume.

Abstract: A pacifier including a shield having a first side, a second side, a top portion, and a bottom portion, and a handle. The handle extends from the first side of the shield and defines a longitudinal axis. A nipple extends from the second side of the shield, wherein the nipple is inclined with respect to the longitudinal axis and extends downwardly from the longitudinal axis.

Abstract: The invention relates to a kit of parts comprising Part A and Part B, Part A comprising: component(s) comprising an ascorbic acid moiety, stabilizer(s) selected from sulphite(s), phosphite(s) or mixtures thereof, optionally polymerizable component(s) without acidic moieties, optionally polymerizable component(s) with acidic moieties, and optionally filler(s), Part B comprising polymerizable component(s) without acidic moieties, polymerizable component(s) with acidic moieties, transition metal component(s), organic peroxide(s), and optionally filler(s). The invention is also directed to an initiator system comprising component(s) comprising an ascorbic acid moiety, stabilizer(s) selected from sulphite(s), phosphite(s) or mixtures thereof transition metal component(s), organic peroxide(s). The kit of parts and redox initiator system are particularly useful in the dental and orthodontic field.

Abstract: Disclosed herein is a micro particle with a diameter of 10-100 microns, wherein the micro particle is coated with silver nanoparticles; and wherein the nanoparticles are coated with a polysaccharide; and wherein the polysaccharide coating is digestible by bacteria. Also, disclosed is a method of making silver nanoparticles using an ascorbic acid derivative or an alpha-hydroxyl carboxylic acid derivative as a reducing agent. The silver nanoparticles may be coated onto micro particles, embedded in hydrogel particles or coated with polysaccharide. The silver nanoparticles may be used in a wound dressing, a bandage, a fungal treatment product, a deodorant, a floss product, a toothpick, a dietary supplement, dental X-ray, a mouthwash, a toothpaste, acne or wound treatment product, skin scrub, and skin defoliate agent.

Abstract: A tooth whitening composition includes a whitening component; a metal ion chelator; water; and polyalcohol, the weight ratio of the water and the polyalcohol being, water:polyalcohol=3.5:1 to 20:1, and also, the total amount of the water and the polyalcohol, in the composition, being greater than or equal to 50 wt. % and less than or equal to 85 wt. %.

Abstract: The present invention includes an ultraviolet radiation absorbing polymer composition comprising the polymer compound of formula and compositions containing such an ultraviolet radiation absorbing polymer composition.

Abstract: Compositions and methods are disclosed for repairing damaged keratin fibers or otherwise strengthening keratin fibers, including hair of the human scalp, and particularly hair that has been damaged chemically, physically, thermally or by other means. The compositions comprise 3,3?-thiodipropionic acid (TDPA) or a derivative thereof in a cosmetically acceptable vehicle.

Abstract: The present invention relates to a composition for inhibiting micro-organisms, as well as related processes, formulations, concentrates and uses. The composition comprises at least 30 wt.-% compound X, wherein compound X is according to Formula (I): wherein R is a saturated or unsaturated hydrocarbon chain having seven or nine carbon atoms, or a mixture thereof.

Abstract: A method of degrading bilirubin in skin is provided. The method involves identifying a target portion of skin where a reduction in bilirubin level is desired, and applying a vitamin B3-containing, low-pH composition to the target portion of skin during a treatment period. The composition contains an effective amount of a vitamin B3 compound, has a pH of less than 5.0, and reduces bilirubin level in the target portion of skin during the treatment period. The amount of vitamin B3 compound and the pH of the composition may be selected to provide a synergistic reduction in bilirubin level, as compared to the reduction in bilirubin level provided by the same composition at a neutral pH.

Abstract: Disclosed are hair styling compositions comprising at least two latex acrylate polymers, wherein at least one latex acrylate polymer is a film-forming polymer. Methods of styling the hair are also disclosed.

Abstract: Hair dyeing process comprising a phosphonic ethylenic polymer and a pigment The invention relates to a process for dyeing hair comprising at least one pigment and at least one phosphonic polymer derived from the polymerization of: (a) 45% to 95% by weight of ethylenic monomer bearing an at least C8 linear or branched alkyl group; (b) 5% to 25% by weight of vinylphosphonic acid monomer; (c) 0 to 50% by weight of additional monomer chosen from: (i) linear or branched C1-C6 alkyl (meth)acrylate or C6-C12 cycloalkyl (meth)acrylate non-silicone monomers; (ii) specific polydimethylsiloxane silicone monomers bearing a mono(meth)acryloyloxy end group.

Abstract: A sunscreen composition including a polymer composition that contains a UV-absorbing polyglycerol having a UV-absorbing chromophore chemically bound thereto, and a cosmetically-acceptable topical carrier that contains at least one percent by weight of the sunscreen composition of a non-UV-absorbing polyglycerol, based on total weight of the sunscreen composition.

Abstract: A cosmetic composition and a topical composition containing a resin-linear organopolysiloxane block copolymer are provided, which are excellent in compatibility with other cosmetic raw materials, so as to have a high degree of freedom in formulation design, excellent film forming properties and film following properties, and suppressed tackiness of the film. The resin-linear organopolysiloxane block copolymer contains a resin-linear organopolysiloxane block copolymer (A) having a structure in which a resin structure (A1) block having a siloxane unit represented by R1SiO3/2 (where R1 is a monovalent organic group, a hydroxyl group, or an alkoxy group having 1 to 6 carbon atoms) or by SiO4/2 and a linear structure (A2) block represented by (R2SiO2/2)n (where n is a number of 5 or more, R is an alkyl group, a fluoroalkyl group, or an aryl group) are connected by a Si—O—Si bond and has an R1SiO3/2 unit.

Abstract: Biodegradable implants sized and suitable for implantation in an ocular region or site and methods for treating ocular conditions. The implants provide an extended release of an active agent at a therapeutically effective amount for a period of time between 50 days and one year, or longer.

Abstract: An implant for insertion through a punctum and into a canalicular lumen of a patient. The implant includes a matrix of material, a therapeutic agent dispersed in the matrix of material, a sheath disposed over a portion of the matrix of material and configured to inhibit the therapeutic agent from being released from the matrix of material into the canalicular lumen and to allow the therapeutic agent to be released from a surface of the matrix of material to a tear film, and a retention structure configured to retain the implant within the canalicular lumen.

Abstract: Disclosed herein, in part, is a pharmaceutical formulation comprising isotretinoin or a pharmaceutically acceptable salt thereof, and a mucoadhesive polymer. A method of treating a mucosal disease comprising administering a disclosed pharmaceutical formulation to a subject in need thereof is also provided herein.

Abstract: The disclosure provides stable formulations of cationic biocides that are primarily used in the treatment and prevention of infections. The disclosure is also concerned with processes for forming stable emulsions of cationic biocides and petrolatum.

Abstract: Disclosed is a ?-cyclodextrin-based star-shaped polymer and a preparation method therefor, and an integrated unimolecular micelle system for diagnosis and treatment based on the star-shaped polymer and the use thereof. The polymer has a structure represented by the following formula (I): wherein x=4-15, y=3-20, and z=10-30.

Abstract: This invention is related to use of exosomes for biomarker analysis for early detecting and characterizing of disease progression of cancer. Further, the invention provides bioengineered exosomes for use in methods of targeting and treating cancer.

Abstract: The present invention relates to polymersomes that contain an encapsulated drug and that exhibit chemotaxis in response to a chemical stimulus. The chemotactic polymersomes can be targeted in vivo to a location of therapeutic interest with high specificity and selectivity. The present invention also provides related pharmaceutical compositions and therapeutic methods.

Abstract: Novel microsphere compositions for use in parenteral formulations are provided. The microspheres comprise a biodegradable polymer of a molecular weight greater than 10,000 daltons, an active therapeutic agent, and a cellulose-derived material such as ethyl cellulose, carboxymethyl cellulose, hydroxypropylmethyl cellulose, or sodium carboxymethyl cellulose. The microsphere compositions decreased deviation in mean microsphere diameter, improved drug entrapment, and improved microsphere stability.

Abstract: The instant application relates to the field of pharmaceutical compositions comprising dasatinb. Furthermore, the instant application relates to a method of treating proliferative disorders in a patient in need thereof, comprising administering a therapeutically effective amount of said compositions.

Abstract: The instant application relates to the field of pharmaceutical compositions comprising dasatinb. Furthermore, the instant application relates to a method of treating proliferative disorders in a patient in need thereof, comprising administering a therapeutically effective amount of said compositions.

Abstract: The present invention relates to novel pharmaceutical formulations which have controlled, delayed release of active ingredient, and to a process for the preparation of such formulations. The invention additionally relates to the use of these novel pharmaceutical administration forms as medicaments for the treatment of diseases which require delayed release of the active ingredient, such as hypertension, or asthmatic diseases.

Abstract: The present invention relates to sustained-release formulations and dosage forms of ruxolitinib, or a pharmaceutically acceptable salt thereof, which are useful in the treatment of Janus kinase-associated diseases such as myeloproliferative disorders.

Abstract: Described herein are pharmaceutical compositions for the oral administration of mesalazine, as well as methods of making such pharmaceutical compositions, and therapeutic methods for using them. The compositions comprise delayed-immediate release and delayed-extended release formulation of mesalazine.

Abstract: The invention relates to a new fixed dose combination of benazepril with pimobendan.

Abstract: The present invention relates to new acid resistant hard pharmaceutical capsules, a process for their manufacture and use of such capsules particularly but not exclusively for oral administration of pharmaceuticals, veterinary products, food and dietary supplements to humans or animals. The capsules of the invention are obtained by aqueous compositions comprising a water soluble film forming polymer and gellan gum in a mutual weight ratio of 4 to 15 weight parts of gellan gum for 100 weight parts of film forming polymer.

Abstract: A composition includes particles of pimobendan with an integral coating of a carrier matrix which serve to ensure a rapid dissolution of the active substance at each pH condition representing the gastrointestinal tract and therefore a reliable absorption, and a method of pimobendan microencapsulation using the spray congealing technology and incorporating the coated particles into oral formulations, for example into tablets.