Patents Issued in January 7, 2021
  • Publication number: 20210000351
    Abstract: A monitoring device for monitoring of vital signs of a living organism comprises at least two electrode pins for receiving an electrical activity of the living organism and an optical sensor for sensing a pulse of the living organism, wherein the monitoring device has a compact form and the at least two electrode pins and the optical sensor are integrated in the monitoring device.
    Type: Application
    Filed: November 24, 2017
    Publication date: January 7, 2021
    Inventors: Srinivasan MURALI, Francisco Javier RINCON VALLEJOS, Sébastien BAUMANN, Ester PÉREZ MARCOS
  • Publication number: 20210000352
    Abstract: Fluorescence based tracking of a light-emitting marker in a bodily fluid stream is conducted by: providing a light-emitting marker into a fluid stream; establishing field of view monitoring by placement of a sensor, such as a high speed camera, at a region of interest; recording image data of light emitted by the marker at the region of interest; determining time characteristics of the light output of the marker traversing the field of view; and calculating flow characteristics based on the time characteristics. Furthermore generating a velocity vector map may be conducted using a cross correlation technique, leading and falling edge considerations, subtraction, and/or thresholding.
    Type: Application
    Filed: September 24, 2020
    Publication date: January 7, 2021
    Inventors: James Bradley Sund, SR., David S. Cohen
  • Publication number: 20210000353
    Abstract: A blood pressure measurement device according to one aspect includes: a blood pressure measurement unit configured to measure blood pressure at a measurement target site of a measurement target subject; a pulse transit time measurement unit configured to measure a pulse transit time at the measurement target site of the measurement target subject; a blood pressure value calculation unit configured to calculate a blood pressure value, on the basis of measurement results of the pulse transit time and a relational expression representing a correlation between the pulse transit time and the blood pressure; a posture instruction unit configured to instruct the measurement target subject to assume a plurality of postures in which height positions of the measurement target site with respect to a heart of the measurement target subject are different from each other; and a calibration unit configured to calibrate the relational expression, on the basis of the blood pressure measured by the blood pressure measurement u
    Type: Application
    Filed: September 23, 2020
    Publication date: January 7, 2021
    Inventors: Kenji FUJII, Yasuhiro KAWABATA, Naomi MATSUMURA, Reiji FUJITA, Akito ITO
  • Publication number: 20210000354
    Abstract: An electronic sphygmomanometer measuring method, comprising: acquiring a barometric pressure sequence (S110); obtaining a systolic pressure/diastolic pressure on the basis of the barometric pressure sequence (S120); extracting characteristic information of the barometric pressure sequence (S130); and correcting the systolic pressure/diastolic pressure on the basis of the characteristic information (S160). The measuring method increases the precision in calculating the systolic pressure/diastolic pressure. Also disclosed accordingly are an electronic sphygmomanometric system, an electronic sphygmomanometer, and a storage medium.
    Type: Application
    Filed: May 29, 2018
    Publication date: January 7, 2021
    Inventor: Wenhan YU
  • Publication number: 20210000355
    Abstract: A stress evaluation device includes a first sensor that measures a heart rate and a heart rate variability of a measurement subject; a calculator that calculates (i) an amount of change in heart rate and (ii) an amount of change in heart rate variability; and a determiner that determines a factor for stress of the measurement subject in accordance with the (i) and the (ii) and that outputs a determination result. The amount of change in heart rate is an amount of change from a reference value to the measured heart rate. The amount of change in heart rate variability is an amount of change from a reference value to the measured heart rate variability. The determiner makes (I) a comparison between the (i) and a first threshold, and (II) a comparison between the (ii) and a second threshold to determine the factor for the stress.
    Type: Application
    Filed: September 23, 2020
    Publication date: January 7, 2021
    Inventors: TAKEHIRO ZUKAWA, YUKIHIRO MORITA
  • Publication number: 20210000356
    Abstract: Embodiments herein provide a system and method for screening and monitoring of cardiac diseases by analyzing acquired physiological signals. Unlike state of art approaches that consider only synchronized ECG and PPG signals for cardiac health analysis and do not consider PCG which is a critical signal for CAD analysis, the system synchronously captures physiological signals such as photo plethysmograph (PPG), phonocardiogram (PCG) and electrocardiogram (ECG) from subject(s) and builds an analytical model in the cloud for analyzing heart conditions from the captured physiological signals. The system and method provides a fusion based approach of combining the captured physiological signals such as PPG, PCG and ECG along with other details such as subject clinical information, demography information and so on. The analytical model is pretrained using ECG. PPG and PCG along with metadata associated with the subject such as demography and clinical information.
    Type: Application
    Filed: July 1, 2020
    Publication date: January 7, 2021
    Applicant: Tata Consultancy Services Limited
    Inventors: Sanjay Madhukar KIMBAHUNE, Sujit Raghunath SHINDE, Arpan PAL, Sundeep KHANDELWAL, Tanuka BHATTACHARJEE, Shalini MUKHOPADHAYAY, Rohan BANERJEE, Avik GHOSE, Tapas CHAKRAVARTY
  • Publication number: 20210000357
    Abstract: A current cancellation circuit, a heart rate detection device and a wearable device. The current cancellation circuit includes: a current-voltage conversion circuit and a SAR ADC, where the SAR ADC includes a DAC, an SAR logic circuit and a comparator; the current-voltage conversion circuit is configured to receive an analog current output by the DAC and an interference current output by a photoelectric sensor, calculate a difference between the analog current and the interference current, and output an analog voltage; the comparator is configured to receive the analog voltage output by the current-voltage conversion circuit, and output a comparison result according to the analog voltage; and the DAC is configured to output the analog current according to a digital signal corresponding to the comparison result that is output by the SAR logic circuit, and the analog current is used to cancel the interference current output by the photoelectric sensor.
    Type: Application
    Filed: September 17, 2020
    Publication date: January 7, 2021
    Inventor: Bo LI
  • Publication number: 20210000358
    Abstract: In some aspects, the described systems and methods provide for a method comprising transmitting to a brain of a patient, with at least one transducer, acoustic signals. The method further comprises receiving from the brain, with the at least one transducer, data acquired from the brain including information related to standing waves, distribution of acoustic modes, frequency response, and/or impulse/transient response. The method further comprises determining, from the acquired data, intracranial pressure of the person.
    Type: Application
    Filed: July 2, 2020
    Publication date: January 7, 2021
    Applicant: EpilepsyCo Inc.
    Inventors: Kamyar Firouzi, Eric Kabrams, Mohammad Moghadamfalahi
  • Publication number: 20210000359
    Abstract: In some aspects, the described systems and methods provide for a method comprising transmitting to a skull of a patient, with at least one transducer, acoustic signals. The method further comprises receiving from the skull, with the at least one transducer, data acquired from the skull including information related to guided waves, distribution of acoustic modes, frequency response, and/or impulse/transient response. The method further comprises determining, from the acquired data, intracranial pressure of the person.
    Type: Application
    Filed: July 2, 2020
    Publication date: January 7, 2021
    Applicant: EpilepsyCo Inc.
    Inventors: Kamyar Firouzi, Eric Kabrams, Mohammad Moghadamfalahi
  • Publication number: 20210000360
    Abstract: In some aspects, the described systems and methods provide for a method comprising transmitting, with at least one transducer, acoustic signals to a brain of a patient, wherein the at least one transducer is configured to induce excitation of a plurality of acoustic modes. The method further comprises receiving, with the at least one transducer, data acquired from the brain including information related to standing waves, frequency response, impulse/transient response, and/or distribution of acoustic modes. The method further comprises determining, from the acquired data, a distribution of intracranial pressure within the brain of the person.
    Type: Application
    Filed: July 2, 2020
    Publication date: January 7, 2021
    Applicant: EpilepsyCo Inc.
    Inventors: Kamyar Firouzi, Eric Kabrams, Mohammad Moghadamfalahi
  • Publication number: 20210000361
    Abstract: A device for measuring a rate of production of urine in a patient comprising a catheter; a pressure transducer; and a means for measuring the amount of urine produced. Urine flow from the bladder is prevented until a predetermined pressure is reached in the bladder. Urine flow is then allowed; the bladder pressure and the volume of urine exiting the bladder are measured. When the bladder pressure reaches a second, lower predetermined pressure, urine flow is again prevented. From the measured pressure during urine flow and from the volume of urine exiting the bladder, the intra-abdominal pressure and the urine production rate can be determined.
    Type: Application
    Filed: November 29, 2018
    Publication date: January 7, 2021
    Inventors: Tomer LARK, Noam HADAS
  • Publication number: 20210000362
    Abstract: The present invention is directed to a method of continuously monitoring neuronal avalanches in a subject comprising (a) determining a deviation in avalanche exponent (?) or branching parameter (?) from a predetermined value at rest, wherein the pre-determined value of a is a slope of a size distribution of the synchronized neuronal activity and the predetermined value is ?3/2 and the pre-determined value of 6 is a ratio of successively propagated synchronized neuronal activity and the predetermined value is 1; and (b) repeating step (a) one or more times to continuously monitor neuronal avalanches in a subject. The invention also features methods of determining or monitoring the degree of sleep deprivation in a subject, methods of identifying subjects that are susceptible to a sleep disorder and methods of diagnosing a sleep disorder in a subject.
    Type: Application
    Filed: September 22, 2020
    Publication date: January 7, 2021
    Applicant: The United States of America, as represented by the Secretary, Department of Health & Human Services
    Inventors: Dietmar Plenz, Oren Shriki, Giulio Tononi, Christian Meisel
  • Publication number: 20210000363
    Abstract: A monitoring system may include a processor and display system for displaying results from the monitoring. A user may be in a sterile field away from the processor and display system and selected input devices. A controller may be physically connected to the monitoring system from the sterile field to allow the user to control the monitoring system.
    Type: Application
    Filed: September 23, 2020
    Publication date: January 7, 2021
    Inventors: Matthew L. Cantwell, Wenjeng Li, Kevin L. McFarlin, Anirudhan Narasimhan
  • Publication number: 20210000364
    Abstract: An electronic device is provided. The electronic device includes a housing, a printed circuit board disposed inside the housing and including a first face and a second face that faces away from the first face, a connection member disposed on the first face and electrically connected to the printed circuit board, a switch member disposed on the first face and at least partially overlaps the connection member when viewed from above the first face, and a button member including an electrically conductive member, and disposed to be capable of operating the switch member. The electrically conductive member is electrically connected to the connection member.
    Type: Application
    Filed: April 28, 2020
    Publication date: January 7, 2021
    Inventors: June LEE, Junhui LEE, Yongyi KIM, Seunghyun CHO
  • Publication number: 20210000365
    Abstract: Disclosed is a method for computerizing delineation and/or multi-label classification of an ECG signal, including: applying a neural network to the ECG, labelling the ECG, and optionally displaying the labels according to time with the ECG signal.
    Type: Application
    Filed: September 17, 2020
    Publication date: January 7, 2021
    Applicant: Cardiologs Technologies SAS
    Inventors: Jeremy RAPIN, Jia LI, Mathurin MASSIAS
  • Publication number: 20210000366
    Abstract: A first calculation unit calculates the heart rate of a subject from a plurality of instantaneous heart rates by averaging processing with an IIR filter using a first coefficient. Note that the first coefficient is a numerical value less than 1, and is a fixed value. A second calculation unit calculates the heart rate of the subject from the plurality of instantaneous heart rates by averaging processing with an IIR filter using a second coefficient. The second coefficient is a numerical value less than 1, and is a variable value. A switching unit switches between the first calculation unit and the second calculation unit based on a difference between the precedingly calculated heart rate and a latest instantaneous heart rate.
    Type: Application
    Filed: March 1, 2019
    Publication date: January 7, 2021
    Inventors: Rieko Sato, Nobuaki Matsuura, Kei Kuwabara, Takayuki Ogasawara
  • Publication number: 20210000367
    Abstract: A first aspect provides, in a device for processing biomedical data obtained from a body, a method of determining brain activity. The method comprises obtaining neuron oscillation signal data of a first part of a brain over a period of time. The oscillation signal data is apportioned in timeslots within the period and per time slot, based on the oscillation data for the timeslot, an amplitude value and variation value representing data values in the timeslot are obtained. A correlation value is determined between the amplitude values and the corresponding variation values over at least a substantial part of the first time period; and the correlation value is provided as an output. The correlation value may optionally be used for estimating a ratio between excitation and inhibition activity of the brain under scrutiny.
    Type: Application
    Filed: March 18, 2019
    Publication date: January 7, 2021
    Applicant: Stichting VU
    Inventors: Klaus LINKENKAER-HANSEN, Richard Edward HARDSTONE
  • Publication number: 20210000368
    Abstract: A mobile ECG system includes: a multiplexor, the multiplexor comprising an input port connected with a plurality of electrodes, two output ports, and a control port; a digital detection module being connected with one output port of the multiplexor; an analog detection module being connected with the other output port of the multiplexor and configured to detect a heart beat without utilizing any portion of the digital detection module; and a processor being connected with the control port of the multiplexor and configured to receive an electrical signal and control the multiplexor through the control port to selectively transmit output of all of the electrodes to the analog detection module or the digital detection module based on the electrical signal.
    Type: Application
    Filed: September 18, 2020
    Publication date: January 7, 2021
    Applicant: Shenzhen Dansha Technology Co., Ltd.
    Inventor: Chunlian DENG
  • Publication number: 20210000369
    Abstract: Electrographic flow mapping (EGF mapping) is a technique used for aiding catheter ablation when treating atrial fibrillation. Visualizing EGF fields during a cardiac catherization and ablation procedure is an important and necessary part of conducting the procedure. Several different visualization methods are described and disclosed herein that may be employed to visualize EGF fields and maps, including quiver plots, streamline plots, particle plots, particle trail plots, moving particle plots, and moving and fading particle plots.
    Type: Application
    Filed: July 1, 2020
    Publication date: January 7, 2021
    Inventors: David Emanuel Luksic, Philip Haeusser, Peter Ruppersberg
  • Publication number: 20210000370
    Abstract: The technology relates to fabricating and employing a sensor unit with a malleable housing to obtain various bio-signals detected while the sensor unit is disposed in the wearer's ear canal. A set of sensor contacts is arranged along an exterior ear-contacting portion of the housing. The malleable material can be compressed for insertion into the ear canal, then automatically expanding to contact the ear canal at multiple points. The sensor contacts are distributed along the exterior of the housing to provide an orientation agnostic configuration. The sensor unit is able to be worn for hours, a day or longer. During wear, the contacts can detect EEG and/or MEG-related signal, such as Alpha waves. Other sensors may be included with the sensor unit to supplement the detection of bio-signals. The obtained signals may be processed on-board or transmitted to a remote device for off-board processing.
    Type: Application
    Filed: April 22, 2020
    Publication date: January 7, 2021
    Inventors: Russell Mirov, Phillip Yee, Jonathan Berent
  • Publication number: 20210000371
    Abstract: A bioelectrode and a method for producing the bioelectrode are provided. The bioelectrode has a non-complicated structure, satisfactory elasticity, and is capable of preventing an increase of contact impedance due to an increase of the number of times of usage. The bioelectrode includes a support member, which is an electrically conductive member, and at least one electrode member, which is a member projecting from the support member. At least the electrode member is molded from an electrically conductive rubber containing a silicone rubber and treated metal particles containing a crosslinkable functional group on a surface thereof.
    Type: Application
    Filed: October 16, 2019
    Publication date: January 7, 2021
    Inventors: Takumi YOSHITOMI, Ryo FUTASHIMA, Toru UDA
  • Publication number: 20210000372
    Abstract: An electrode system includes an electrode, a connector, and a cable with an in-line radio-frequency filter module comprising resistors and inductors without any deliberately added capacitance. The resistors are arranged in an alternating series of resistors and inductors, preferably with resistors at both outer ends, and connected electrically in series. The in-line module is located at a specific location along the wire, chosen through computer modeling and real-world testing for minimum transfer of received RF energy to a patient's skin, such as between 100 cm and 150 cm from the electrode end of a 240 centimeter cable. The total resistance of the resistors plus cable, connectors and solder is 1000 ohms or less; while the total inductance is roughly 1560 nanohenries. The inductors do not include ferrite or other magnetic material and are, together with the resistors, stock components thereby simplifying manufacture and reducing cost.
    Type: Application
    Filed: September 15, 2020
    Publication date: January 7, 2021
    Inventors: James W. KRONBERG, Harrison FLOYD, Daniel E. MCCOY, Gabriel ORSINGER
  • Publication number: 20210000373
    Abstract: A method of fabricating an ear tip including the steps of: providing an ear tip for an earpiece including a body having first and second ends, an inner wall extending between the first and second ends, and an outer wall connected to the inner wall of the body at the first end and tapering away from the inner wall toward the second end; and forming a first electrically conductive element along the outer surface of the outer wall and an inner surface of the inner wall; or forming a first electrically conductive element on an outer surface of the deformable outer wall and a second electrically conductive element connected to the first electrically conductive element, wherein the second electrically conductive element extends along an inner surface of the outer wall and an outer surface of the inner wall.
    Type: Application
    Filed: September 17, 2020
    Publication date: January 7, 2021
    Applicant: Bose Corporation
    Inventors: Shawn Prevoir, Andrew D. Dominijanni, Thomas J. Peters, JR., Harsh Anilkant Mankodi, Yang Liu, Corey Ann Le
  • Publication number: 20210000374
    Abstract: A method and system for instructing a user behavior change comprising: collecting a first and a second bioelectrical signal dataset; generating an analysis based upon the first and the second bioelectrical signal datasets; and providing a behavior change suggestion to the user based upon the analysis. The method can further comprise collecting a third bioelectrical signal dataset associated with a performance of an action by the user in response to the behavior change suggestion; generating an adherence metric based upon the third bioelectrical signal dataset and at least one of the first and the second bioelectrical signal datasets; providing a stimulus configured to prompt an action by the user; and providing at least one of the analysis and an analysis based upon the adherence metric to the user. An embodiment of the system comprises a biosignal detector and a processor configured to implement an embodiment of the method.
    Type: Application
    Filed: September 14, 2020
    Publication date: January 7, 2021
    Inventors: Tan Le, Geoffrey Mackellar
  • Publication number: 20210000375
    Abstract: Some embodiments of the present disclosure are directed to methods, systems and probe devices for detecting EMG activity. In some embodiments, such methods, systems and devices are used in aiding the diagnosis of Obstruction Sleep Apnea (OSA). In some embodiments, a probe is provided and comprises an elongated member configured with a size and shape for placement adjacent at least one of the soft palate and pharyngeal wall of the patient after insertion of the probe into the patient. The probe may also include at least one sensor configured to sense at least EMG activity of muscle layers of at least one of the soft palate and pharyngeal wall and output sensor signals corresponding thereto. The signals may be monitored for EMG activity, and based on such activity, in some embodiments, a determination of whether the sensor signals of the detected EMG activity correspond to spontaneous EMG activity and/or abnormal motor unit potentials (MUPs).
    Type: Application
    Filed: March 16, 2020
    Publication date: January 7, 2021
    Applicant: Powell Mansfield, Inc.
    Inventors: Nelson Powell, Perry T. Mansfield
  • Publication number: 20210000376
    Abstract: An electronic device according to various embodiments of the present invention comprises: a sensor module; a first electrode unit connected to a first channel of the sensor module; and a second electrode unit connected to a second channel of the sensor module, and may be configured to: measure, through the sensor module, a first impedance between the first electrode unit and a first portion of a user's body contacting the first electrode unit, and a second impedance between the second electrode unit and a second portion of the user's body contacting the second electrode unit; adjust, through the sensor module, an impedance corresponding to each of the first channel and the second channel on the basis of the first impedance and the second impedance so that a difference between the first impedance and the second impedance is within a specified range; and obtain a biometric signal of the user through the sensor module while the impedance of the first channel and the second channel are adjusted.
    Type: Application
    Filed: November 20, 2018
    Publication date: January 7, 2021
    Inventors: Suho LEE, Younghyun KIM, Seungeun LEE
  • Publication number: 20210000377
    Abstract: A kit for transmitting and sensing signals comprises: a multi-connection cable having a plurality of cable connectors at a distal end of the cable for establishing electrical communication between each of the cable connectors and a system for measuring bioimpedance that is connectable to a proximal end of the cable, and a plurality of devices for transmitting and sensing signals. Each device comprises a non-conductive substrate adherable to a skin of a subject, a first and a second electrical contacts printed on the substrate, and a disposable connector. Each disposable connector is connectable to a compatible cable connector of the cable in a manner that a combined thickness of the disposable connector and the compatible cable connector, once connected, is less than 4 mm.
    Type: Application
    Filed: June 30, 2020
    Publication date: January 7, 2021
    Inventors: Yochay Kaplan, Baruch Levy, Eliezer Schusman, Mordechai Dinour
  • Publication number: 20210000378
    Abstract: A device for transmitting and sensing signals comprises a non-conductive substrate adherable to a skin of a subject, two or more electrical contacts printed on the substrate, and a disposable connector, connectable to a compatible cable connector of a cable which receives signals from the contacts via the disposable connector. The disposable connector has a symmetric shape such that mating between the disposable connector and the compatible cable connector is established at either one of two flipped orientations.
    Type: Application
    Filed: June 30, 2020
    Publication date: January 7, 2021
    Inventors: Yochay Kaplan, Baruch Levy, Eliezer Schusman, Mordechai Dinour
  • Publication number: 20210000379
    Abstract: A surgical instrument can include a body, a tracking device, and a handle. The tracking device can be positioned adjacent the distal end for tracking a distal tip of the instrument. The tracking device can include a pair of lead traces defined on a tubular flex circuit around the body to the handle, where the traces define at least on coil configured to communicate with a navigation system.
    Type: Application
    Filed: September 17, 2020
    Publication date: January 7, 2021
    Inventors: Frank STRUPECK, Abhishek JAIN, Bruce M. BURG, Brad JACOBSEN
  • Publication number: 20210000380
    Abstract: System and methods are disclosed to facilitate intra-operative procedures and planning. A method can include storing tracking data in memory, the tracking data being generated by a tracking system to represent a location of an object in a tracking coordinate system of the tracking system. The method can also include storing a patient-specific implicit model in memory, the patient-specific implicit model being generated based on image data acquired for the patient to define geometry of an anatomical structure of the patient. The method can also include registering the tracking data and the patient-specific implicit model in a common three-dimensional coordinate system. The method can also include generating an output visualization representing a location of the object relative to the geometry of the anatomical structure of the patient in the common coordinate system.
    Type: Application
    Filed: September 22, 2020
    Publication date: January 7, 2021
    Inventors: Karl West, Vikash Goel, James Foster
  • Publication number: 20210000381
    Abstract: Aspects of the present disclosure are directed to apparatuses for generating a magnetic field for tracking of a target object. Such an apparatus may include a localized magnetic field transmitter that generates a magnetic field and exhibits minimal X-ray absorption when used in proximity to a fluoroscopic imaging system, for example.
    Type: Application
    Filed: February 11, 2019
    Publication date: January 7, 2021
    Inventors: Alon Izmirli, Guy Hevel, Adrian Herscovici, Yuval Vaknin, David Jacobs
  • Publication number: 20210000382
    Abstract: Probes and related systems and methods are provided for localizing markers implanted within a patient's body. The probe includes an antenna assembly adjacent a distal end thereof including a ceramic base including a planar distal surface and four proximal surfaces extending at an angle relative to a longitudinal axis of the probe to define a generally pyramidal shape. The base includes antenna elements on the proximal surfaces and radial slots between adjacent proximal surfaces to substantially isolate the antenna elements from one another. A controller is coupled to the antenna elements for transmitting signals into a patient's body and receiving reflected signals reflected from a marker implanted within the patient's body to identify and/or localize the marker.
    Type: Application
    Filed: June 30, 2020
    Publication date: January 7, 2021
    Inventors: John E. Greene, Jonathan Edward White, Kohl Ian Thorlakson
  • Publication number: 20210000383
    Abstract: A capacitive sensor includes a sensor body having a cavity. The sensor body is non-electrically conductive. The sensor also includes a first diaphragm having a metallic conductor layer. The first diaphragm is arranged on the sensor body on a first side of the cavity. The sensor further includes a second diaphragm having a metallic conductor layer. The second diaphragm is arranged on the sensor body on a second side of the cavity. An air gap is formed in the cavity between the first and second diaphragms, the air gap having a height equal to a height of the sensor body.
    Type: Application
    Filed: April 8, 2019
    Publication date: January 7, 2021
    Inventors: Muhammad Mustafa HUSSAIN, Sherjeel KHAN
  • Publication number: 20210000384
    Abstract: Methods and apparatus for monitoring a human or animal subject are disclosed. In one arrangement, measurement data representing a time series of measurements on a subject is received. The measurement data is represented as a mathematical expansion comprising a plurality of expansion components and expansion coefficients. First and second partial reconstructions are performed using first and second subsets of the expansion components. First and second spectral analyses are performed on the first and second partial reconstructions to determine first and second dominant frequencies. A frequency of a periodic physiological process is derived based on either or both of the first and second dominant frequencies.
    Type: Application
    Filed: January 22, 2019
    Publication date: January 7, 2021
    Inventors: Delaram JARCHI, David CLIFTON, Lionel TARASSENKO
  • Publication number: 20210000385
    Abstract: A portable smart device for monitoring hypoxia in a user over a period of time. The portable smart device configured to analyze the heart rate signal of the user to determine at least one of an interbeat interval (IBI) or an amplitude or a heart rate variability (HRV) of the heart rate signal, determine from the at least one of the IBI or the amplitude or the HRV, and without computing oxygen saturation in the blood, an occurrence of hypoxia over a period of time in the monitoring session, determine a length of the occurrence and an intensity of the occurrence of the hypoxia based on a change in the IBI or the amplitude or the HRV over a time period.
    Type: Application
    Filed: August 19, 2020
    Publication date: January 7, 2021
    Inventors: Anthony C. Warren, Kyle H. Goldschmidt
  • Publication number: 20210000386
    Abstract: The present invention provides a system for determining power output and propulsion efficiency of a user's limb during limbed propulsion; the system comprising: (a) at least two or more accelerometers to measure the acceleration of the limb in at least two substantially orthogonal planes, (b) a processor means to calculate the power output generated by the limb to derive a limb propulsion efficiency measure, and (c) a transmission means to send the limb power output and limb propulsion efficiency metrics to a receiving device; and wherein the system is wearable on the user's limb.
    Type: Application
    Filed: March 1, 2019
    Publication date: January 7, 2021
    Inventor: Dean Kenneth Whiteman
  • Publication number: 20210000387
    Abstract: In accordance with one embodiment, a method for a health scanning system is disclosed. The method includes receiving at least one electrical physiological data signal (PDS); suppressing a Direct Current (DC) signal component of the PDS to emphasize the Alternating Current (AC) signal component of the PDS; isolating the signal noise in the AC signal component of the PDS; and extracting a noise signature from the signal noise in the PDS. The noise signature, after calibration, can be used to uniquely identify a known user from other users.
    Type: Application
    Filed: January 11, 2020
    Publication date: January 7, 2021
    Inventor: Martin Zizi
  • Publication number: 20210000388
    Abstract: A health monitoring device is provided, and may be used in population health monitoring and disease tracing, as well as for individual subject health purposes. The health monitoring device comprises a triboelectric nanogenerator (TENG) for generating and storing electrical energy from mechanical activity of a user. The device provides a continuous and uninterrupted stream of physiological data received at a surface of the device in contact with a surface of the user. The triboelectric nanogenerator is a paper-based device comprising a paper-based material layer and a polydimethylsiloxane/polytetrafluoroethylene (PDMS/PTFE) material layer, each on a copper film. The device has enhanced sensitivity to motion, providing an improved device capable of converting small amounts of movement into electrical energy, and of recording and transmitting data of small physiological changes of a user to a receiver. The device is lithium free, and eliminates the necessity of recharging.
    Type: Application
    Filed: June 26, 2020
    Publication date: January 7, 2021
    Inventors: Mohammed Jasim Uddin, Aminur Rashid Chowdhury, Ulises Vidaumi Romero
  • Publication number: 20210000389
    Abstract: An information processing system includes processing circuitry that is configured to receive input data from a shock sensor which outputs data based on a shock on the shock sensor, and identify a target segment of time-series data that is output from a motion sensor that senses a motion of an object. The target segment includes a pre-shock portion that occurs before the shock event and a post-shock portion that occurs after the shock event, the shock event is recognized based on the data from the shock sensor.
    Type: Application
    Filed: September 3, 2020
    Publication date: January 7, 2021
    Applicant: Sony Corporation
    Inventors: Hideyuki MATSUNAGA, Kosei YAMASHITA
  • Publication number: 20210000390
    Abstract: The invention provides systems and methods for tissue-mounted photonics. Devices of some embodiments implement photonic sensing and actuation in flexible and/stretchable device architectures compatible with achieving long term, mechanically robust conformal integration with a range of tissue classes, including in vivo biometric sensing for internal and external tissues. Tissue-mounted photonic systems of some embodiments include colorimetric, fluorometric and/or spectroscopic photonics sensors provided in pixelated array formats on soft, elastomeric substrates to achieve spatially and/or or temporally resolved sensing of tissue and/or environmental properties, while minimize adverse physical effects to the tissue. Tissue-mounted photonic systems of some embodiments enable flexible passive or active optical sensing modalities, including sensing compatible with optical readout using a mobile electronic devices such as a mobile phone or tablet computer.
    Type: Application
    Filed: July 2, 2020
    Publication date: January 7, 2021
    Inventor: John A. ROGERS
  • Publication number: 20210000391
    Abstract: A method of monitoring an analyte in blood, particularly glycated-haemoglobin (HbA1c or HgbA1c) using two photoplethysmocharty (PPG) sensors, which are worn on the body of a subject. Each photoplethysmocharty sensor observes blood of the subject in a different wavelength. One of the wavelengths monitors glycated-haemoglobin. The other one of the wavelengths monitors the body of blood in general. The shapes of the pulses obtained by each of the PPG sensor from the subject are used to adjust the intensity of the light emitted by the PPG sensors into the subject. If on adjustment of the light intensity, the shapes of the pulses become similar, the size of the pulses can be used to provide quasi-quantification of the analyte.
    Type: Application
    Filed: March 20, 2019
    Publication date: January 7, 2021
    Inventor: Ming Yip Wallace WONG
  • Publication number: 20210000392
    Abstract: The present disclosure relates to noninvasive methods, devices, and systems for measuring various blood constituents or analytes, such as glucose. In an embodiment, a light source comprises LEDs and super-luminescent LEDs. The light source emits light at at least wavelengths of about 1610 nm, about 1640 nm, and about 1665 nm. In an embodiment, the detector comprises a plurality of photodetectors arranged in a special geometry comprising one of a substantially linear substantially equal spaced geometry, a substantially linear substantially non-equal spaced geometry, and a substantially grid geometry.
    Type: Application
    Filed: September 24, 2020
    Publication date: January 7, 2021
    Inventors: Jeroen Poeze, Marcelo Lamego, Sean Merritt, Cristiano Dalvi, Hung Vo, Johannes Bruinsma, Ferdyan Lesmana, Massi Joe E. Kiani, Greg Olsen
  • Publication number: 20210000393
    Abstract: The present disclosure provides, as a film structure useful for a probe of a biosensor, a film structure comprising a detection layer including an analyte-responsive enzyme; and a protection film formed on the detection layer, in which the protection film includes a copolymer mixture including poly(styrene-ran-4-vinylpyridine-ran-propyleneglycol methacrylate); and poly(4-vinylpyridine)-block-poly(C1-15 alkyl methacrylate), or poly(4-vinylpyridine-ran-2-hydroxyethyl methacrylate).
    Type: Application
    Filed: January 28, 2019
    Publication date: January 7, 2021
    Applicant: PHC Holdings Corporation
    Inventors: Takashi ENDOH, Junko IKEDA
  • Publication number: 20210000394
    Abstract: Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.
    Type: Application
    Filed: September 21, 2020
    Publication date: January 7, 2021
    Inventors: Sebastian Böhm, Daiting Rong, Peter C. Simpson
  • Publication number: 20210000395
    Abstract: A microfluidic system includes a flexible substrate having a skin-facing surface and a back-facing surface; a microfluidic network at least partially embedded in or supported by the flexible substrate; a sensor fluidically connected to the microfluidic network, wherein the microfluidic network is configured to transport a biofluid from a skin surface to the sensor; and a capping layer, having a capping layer skin-facing surface and a back-facing surface, wherein the back-facing surface of the capping layer is attached to the skin-facing surface of the substrate. The flexible substrate is at least partially formed of a thermoplastic elastomer or a polymer configured to provide a high barrier to vapor or liquid water transmission.
    Type: Application
    Filed: September 22, 2020
    Publication date: January 7, 2021
    Inventors: John A. ROGERS, Jungil CHOI, Tyler R. RAY, Johnathan T. REEDER, Yurina SEKINE, Amay J. BANDODKAR, Yi ZHANG, Hexia GUO, Sungbong KIM, Diana OSTOJICH
  • Publication number: 20210000396
    Abstract: Methods and devices and systems including a communication module operatively coupled to a data collection module for communicating the stored analyte related data after the analyte related data is stored in the data collection module over a predetermined time period, and a user interface unit configured to communicate with the communication module to receive from the communication module the stored analyte related data in the data collection module over the predetermined time period, and to output information associated with the monitored analyte level, where the user interface unit is configured to operate in a prospective analysis mode including substantially real time output of information associated with the monitored analyte level, or a retrospective analysis mode including limited output of information during the predetermined time period wherein no information related to the monitored analyte level is output during the predetermined time period, are provided.
    Type: Application
    Filed: September 11, 2020
    Publication date: January 7, 2021
    Applicant: Abbott Diabetes Care Inc.
    Inventors: Daniel Milfred Bernstein, Jared Watkin, Martin J. Fennell, Mark Kent Sloan, Michael Love, Namvar Kiaie, Jean-Pierre Cole, Steve Scott
  • Publication number: 20210000397
    Abstract: A non-invasive method and apparatus utilizing a single wavelength (800 nm, isobestic) for the instantaneous, reflective, non-pulsatile spatially resolved reflectance system, apparatus and mathematics that allows for the correct determination of critical photo-optical parameters in vivo. Transcutaneous blood constituent (analyte or drug level) measurements can be determined in real-time. The “closed-form” nature of the mathematics with inclusion of other wavelengths (660 nm and 1300 nm) and a non-invasive transmissive array allows for immediate calculation and real-time display of Hematocrit, Hemoglobin, fractional tissue blood volume (Xb), Hematocrit-Independent Oxygen Saturation, fractional tissue water content (Xw) and other pertinent blood/plasma values in a variety of handheld or other like devices.
    Type: Application
    Filed: June 15, 2020
    Publication date: January 7, 2021
    Inventor: Robert Ricky Steuer
  • Publication number: 20210000398
    Abstract: An oximetry probe and an operating method thereof, and an oximetry sensor. The oximetry probe includes an oximetry sensor which includes a detection end and an output end, and an adapter. The detection end includes a photodetector and multiple light-emitting elements connected in series. The output end has multiple output ports. Adjacent output ports are electrically connected to two sides of the corresponding light-emitting element. The adapter has a first adapter end and a second adapter end between which multiple wires are provided. The first adapter end is electrically connected with an input end of the monitor. When the second adapter end is connected to the output end, the wires are electrically connected with the output ports to form closed circuit to enable the light-emitting element to emit light which is received by the photodetector to generate a signal involving blood oxygen saturation to be displayed on the monitor.
    Type: Application
    Filed: September 21, 2020
    Publication date: January 7, 2021
    Inventors: Ganbing WANG, Chunhui XU
  • Publication number: 20210000399
    Abstract: An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices.
    Type: Application
    Filed: September 23, 2020
    Publication date: January 7, 2021
    Inventors: Samuel M. Curry, Manuel L. Donnay, Tuan Nguyen, Louis G. Pace, Peter G. Robinson, Phillip Yee
  • Publication number: 20210000400
    Abstract: An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices.
    Type: Application
    Filed: September 23, 2020
    Publication date: January 7, 2021
    Inventors: Samuel M. Curry, Manuel L. Donnay, Tuan Nguyen, Louis G. Pace, Peter G. Robinson, Phillip Yee