Patents Issued in January 21, 2021
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Publication number: 20210015369Abstract: Provided is a guidewire connector that does not interfere with an introduction of another in-body insertion instrument and is capable of maintaining cleanliness of the guidewire when connecting a guidewire mounted with a photo-acoustic ultrasonic wave generator. The guidewire connector according to the present disclosure includes an adapter member detachably attached to an light emitting apparatus, and a wire fixing member attaching the guidewire to the adapter member, in which the wire fixing member has an outer diameter equal to or smaller than an outer diameter of the guidewire.Type: ApplicationFiled: May 26, 2020Publication date: January 21, 2021Inventors: Ryo IMAI, Tomohiko TANAKA
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Publication number: 20210015370Abstract: Method and apparatus can be provided according to an exemplary embodiment of the present disclosure. For example, with at least one first section of an optical enclosure, it is possible to provide at least one first electro-magnetic radiation. In addition, with at least one second section provided within the enclosure, it is possible to cause, upon impact by the first radiation, a redirection of the first radiation to become at least one second radiation. Further, with at least one third section of the optical enclosure, it is possible to cause at least one second radiation to be provided to a tissue. For example, the redirection of the first radiation causes, at least approximately, a uniform optical illumination on of a surface of the tissue.Type: ApplicationFiled: October 6, 2020Publication date: January 21, 2021Inventors: Li Li, Guillermo J. Tearney
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Publication number: 20210015371Abstract: Apparatus and methods are described including pressure-sensing apparatus configured to be placed in contact with a portion of a body of a patient. A camera acquires one or more images of the patient. At least one computer processor is configured to estimate a location of a heart of the patient, by analyzing the one or more images of the patient. The computer processor estimates a difference in height between the portion of the patient's body that is in contact with the pressure-sensing apparatus and the estimated location of the patient's heart, and generates an output, at least partially in response thereto. Other applications are also described.Type: ApplicationFiled: October 2, 2020Publication date: January 21, 2021Inventors: Daniel Glozman, Zev Sohn, Yonatan Amir
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Publication number: 20210015372Abstract: Systems and methods for identifying growth of a cerebral aneurysm. The method includes forming a first virtual skeleton model from a first image segmentation and forming a second virtual skeleton model from a second image segmentation. The virtual skeleton models including a plurality of edges with each edge having a plurality of skeleton points. Each skeleton point is associated with a subset of a plurality of blood vessel surface points. The method includes identifying one or more second terminal points within the second virtual skeleton model and overlapping the first virtual skeleton model and the second virtual skeleton model by orienting the one or more first terminal points with the one or more second terminal points.Type: ApplicationFiled: July 18, 2019Publication date: January 21, 2021Inventors: Val Smiricinschi, Kristen Catherine Karman-Shoemake, Mohamed Haithem Babiker
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Publication number: 20210015373Abstract: Systems and methods for classifying and measuring a cerebral aneurysm of a parent vessel. The method includes identifying a potential aneurysm and determining whether the potential aneurysm is a saccular aneurysm type or a fusiform aneurysm type. If the potential aneurysm is the saccular aneurysm type then determining a neck-plane and a neck width of the neck-plane. If the potential aneurysm is the fusiform aneurysm type then determining a distal plane and a proximal plane.Type: ApplicationFiled: July 18, 2019Publication date: January 21, 2021Inventors: Val Smiricinschi, Kristen Catherine Karman-Shoemake, Mohamed Haithem Babiker
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Publication number: 20210015374Abstract: An electronic blood pressure meter according to the present invention includes: a cuff pressure control unit capable of changing a pressure of a cuff worn on a measurement site; a pressure detection unit that detects a cuff pressure signal representing the pressure of the cuff; a variation amount calculation unit that obtains a blood pressure variation amount synchronized with respiration based on the cuff pressure signal; a correspondence relation storage unit that stores a predetermined correspondence relation between a blood pressure variation amount synchronized with respiration and a heart failure index that numerically represents relative severity of heart failure and corresponds to a value of a biomarker indicating severity of heart failure; and an index output unit that refers to the correspondence relation stored in the correspondence relation storage unit and outputs the heart failure index corresponding to the blood pressure variation amount obtained by the variation amount calculation unit.Type: ApplicationFiled: October 5, 2020Publication date: January 21, 2021Applicant: OMRON HEALTHCARE CO., LTD.Inventor: Yukiya SAWANOI
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Publication number: 20210015375Abstract: A method for monitoring a fetal heart rate may include the steps of: acquiring fetal heart rate monitoring data; determining a fetal heart rate value by dividing the acquired fetal heart rate monitoring data by a predetermined time interval; and determining a fetal state by applying, to the determined fetal heartbeat value, a learned artificial intelligence algorithm using a learning database including the fetal heartbeat monitoring data pre-acquired in association with a plurality of fetuses.Type: ApplicationFiled: March 27, 2019Publication date: January 21, 2021Applicants: UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION, THE ASAN FOUNDATIONInventors: Chong Jai KIM, Eun Na KIM
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Publication number: 20210015376Abstract: An electronic device and a method for measuring heart rate are disclosed. A heart rate measuring method of an electronic device, according to the present invention, comprises the steps of: capturing an image including a user's face; grouping the user's face, included in the image, into a plurality of regions including a plurality of pixels of similar colors; acquiring an information on a user's heart rate by inputting information on the plurality of grouped regions to an artificial intelligence learning model; and outputting the acquired information on heart rate. Therefore, the electronic device can measure the user's heart rate more accurately through the captured image.Type: ApplicationFiled: March 6, 2019Publication date: January 21, 2021Applicant: SAMSUNG ELECTRONICS CO., LTD.Inventors: Gyehyun KIM, Joonho KIM, Hyungsoon KIM, Taehan LEE, Jonghee HAN, Sangbae PARK, Hyunjae BAEK
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Publication number: 20210015377Abstract: A device, method and system for calculating, estimating, or monitoring the blood pressure of a subject. A first signal representing heart activity of a subject may be received. A plurality of second signals representing time-varying information on at least one pulse wave of the subject may be received from a plurality of body locations of the subject. A first feature of the first signal may be identified. For each of the plurality of second signals, a second feature may be identified. A pulse transit time based on a difference of the first feature and at least one of the second features may be computed. A blood pressure of the subject may be calculated according to a model based on the computed pulse transit time. The model may include a compensation term relating to the plurality of second signals or the second features thereof.Type: ApplicationFiled: October 1, 2020Publication date: January 21, 2021Applicant: VITA-COURSE TECHNOLOGIES CO., LTD.Inventors: Chuanmin WEI, Ting MA, Jiao YU, Zhiyong WANG, Jiwei ZHAO
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Publication number: 20210015378Abstract: The biological information measurement device (100) includes: a clip (110) that is attached on the scapha of an auricle in such a way as to clamp the scapha from both sides; and a pulse wave sensor (120) that is disposed on a portion of the clip (110), is arranged in such a way as not to compress the helix when the clip (110) is attached on the scapha of the auricle, and measures biological information of an artery running in the helix. The pulse wave sensor (120) may be a non-contact type sensor that measures the biological information, using transmitted light, and the clip (110) may be configured in such a way that the pulse wave sensor (120) does not come into contact with the helix when the clip (110) is attached in such a way as to clamp the scapha of the auricle from both sides.Type: ApplicationFiled: March 28, 2019Publication date: January 21, 2021Inventor: Yuichi Kato
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Publication number: 20210015379Abstract: Systems and methods are provided for determining the frequency of a cardiovascular pulse based on a first physiological signal that is continuously available and a second physiological signal that is less available and that is more accurate or otherwise improved relative to the first signal with respect to pulse rate estimation. When the second signal is available it controls the determination of the pulse rate. When the second signal is unavailable, the first signal is used to determine the pulse rate. This can include using the first signal to estimate the pulse rate until the second signal is available, at which point the pulse rate is estimated based on the second physiological signal. Alternatively, the first signal could be used to determine a number of candidate pulse rates, and the second signal could be used to select a pulse rate from the set of candidate pulse rates.Type: ApplicationFiled: September 25, 2020Publication date: January 21, 2021Inventors: Mark Murphy, Russell Norman Mirov, Christopher Towles Lengerich
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Publication number: 20210015380Abstract: A multi-lumen catheter for monitoring intrauterine pressure comprising an elongated body configured and dimensioned for insertion into a uterus of a patient, the catheter having a first lumen, a second lumen, and a first balloon at a distal portion. The first lumen communicates with the first balloon and the second lumen has an opening within the uterus for injection of x-ray dye or other fluid into the uterus for imaging the uterine cavity and the fallopian tubes of a patient. The first balloon contains a gas to form along with the first lumen a chamber to monitor pressure within the uterus to thereby determine if excessive pressure is being applied to the fallopian tubes of the patient. A sensor is in communication with the first lumen to measure pressure about a circumferential area of the balloon to measure pressure in the uterus to provide readings of intrauterine pressure.Type: ApplicationFiled: September 25, 2020Publication date: January 21, 2021Applicant: Sentinel Medical Technologies, LLCInventors: Timothy McKinney, Marc-Alan Levine
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Publication number: 20210015381Abstract: An intravascular catheter for peri-vascular nerve activity sensing or measurement includes multiple needles advanced through supported guide tubes (needle guiding elements) which expand with open ends around a central axis to contact the interior surface of the wall of the renal artery or other vessel of a human body allowing the needles to be advanced though the vessel wall into the perivascular space. The system also may include means to limit and/or adjust the depth of penetration of the needles. The catheter also includes structures which provide radial and lateral support to the guide tubes so that the guide tubes open uniformly and maintain their position against the interior surface of the vessel wall as the sharpened needles are advanced to penetrate into the vessel wall.Type: ApplicationFiled: August 4, 2020Publication date: January 21, 2021Inventors: David R. Fischell, Tim A. Fischell, Vartan Ghazarossian, Steven Almany
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Publication number: 20210015382Abstract: The present invention provides a system for vehicle security, personalization, cardiac activity and respiratory monitoring of a driver wherein active electrocardiography of a driver is mapped and in case of drivers' abnormal heart numbers or passing out under the influence of alcohol, the monitor takes the control of the vehicle and stops it precisely. The monitor further makes the automatic emergency call to pre-input contact and also provide the security to vehicle to restrict unauthorized access.Type: ApplicationFiled: July 15, 2019Publication date: January 21, 2021Inventor: Melissa Black
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Publication number: 20210015383Abstract: A method for mapping atrial fibrillation (AF) in a heart, the method includes receiving an electrogram (EGM) signal, which is acquired at a given position in the heart, and is exhibiting the AF. Two or more primary peaks are identified in the EGM signal, and a cycle length (CL) is calculated between adjacent primary peaks. One or more secondary peaks are identified in the EGM signal within the CL. A local fragmentation index (FI) that is indicative of a number of the secondary peaks per CL, is calculated. The local FI is visualized on a map of at least part of the heart.Type: ApplicationFiled: July 16, 2019Publication date: January 21, 2021Inventors: Ziyad Zeidan, Aharon Turgeman, Benjamin Cohen, Yaron Kadoshi
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Publication number: 20210015384Abstract: The present invention provides a biological electrode including an electro-conductive base material and a living body contact layer formed on the electro-conductive base material; wherein the living body contact layer includes a resin layer and particles dispersed in the resin layer, the particles being coated with gold, silver, or platinum, and a thickness of the resin layer is equal to or thinner than an average particle size of the particles. The biological electrode of the present invention is superior in electric conductivity and biocompatibility, light in weight, and can be manufactured at low cost.Type: ApplicationFiled: October 2, 2020Publication date: January 21, 2021Applicant: SHIN-ETSU CHEMICAL CO., LTD.Inventors: Jun HATAKEYAMA, Motoaki IWABUCHI
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Publication number: 20210015385Abstract: A biological signal detection system includes one or more magnetic field sensors for placement on a user and for detecting signals generated by biological magnetic field sources of the user; at least one memory; at least one processor coupled to the at least one memory and the one or more magnetic field sensors and configured to receive the detected signals of the one or more magnetic field sensors. The at least one processor is configured to perform actions including receiving the detected signals from the magnetic field sensors; determining whether the detected signals are modulated by a predetermined stimulus tag; and, in response to the determination, identifying which of the detected signals are modulated by the predetermined stimulus tag.Type: ApplicationFiled: July 14, 2020Publication date: January 21, 2021Inventors: Husam Katnani, Antonio Lara, Arnulf Graf, Julien Dubois
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Publication number: 20210015386Abstract: A computer implemented method and system for detecting arrhythmias in cardiac activity are provided. The method is under control of one or more processors configured with specific executable instructions. The method obtains far field cardiac activity (CA) signals and applies a direction related responsiveness (DRR) filter to the CA signals to produce DRR filtered signals. The method compares a current sample from the CA signals to a prior sample from the DRR filtered signals to identify a direction characteristic of the CA signals and defines the DRR filter based on a timing constant that is set based on the direction characteristic identified. The method analyzes the CA signals in connection with the DRR filtered signals to identify a peak characteristic of the CA signals and determines peak to peak intervals between successive peak characteristic. The method detects at least one of noise or an arrhythmia based on the peak to peak intervals and records results of the detecting.Type: ApplicationFiled: October 1, 2020Publication date: January 21, 2021Inventors: Gene A. Bornzin, Fady Dawoud, Jong Gill, Stuart Rosenberg, Fujian Qu, Neha Malhotra
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Publication number: 20210015387Abstract: The system and method provide for electrocardiogram analysis and optimization of patient-customized cardiopulmonary resuscitation and therapy delivery. An external medical device includes a housing and a processor within the housing. The processor can be configured to receive an input signal for a patient receiving chest compressions and to select at least one filter mechanism and to apply the filter mechanism to the signal to at least substantially remove chest compression artifacts from the signal. A real time dynamic analysis of a cardiac rhythm is applied to adjust and integrate CPR prompting of a medical device. Real-time cardiac rhythm quality is facilitated using a rhythm assessment meter.Type: ApplicationFiled: October 1, 2020Publication date: January 21, 2021Inventors: Joseph L. Sullivan, Ronald E. Stickney, Robert G. Walker, Daniel W. Piraino, Isabelle Banville, Fred W. Chapman
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Publication number: 20210015388Abstract: An electronic device includes a housing including a first cover member, a second cover member, and a side member enclosing a space between the first cover member and the second cover member; a support member coupled to or formed integrally with the side member; a printed circuit board disposed in the space and including a biometric circuit; a first conductive portion disposed at least partially in the side member; a second conductive portion and third conductive portion disposed at least partially in the second cover member and electrically connected to the printed circuit board; and at least one conductive path disposed in the space, configured to electrically connect the biometric circuit and the first conductive portion, and formed on the support member. The biometric circuit receives a biometric signal based on the first conductive portion, the second conductive portion, the third conductive portion, and the at least one conductive path.Type: ApplicationFiled: July 17, 2020Publication date: January 21, 2021Inventors: Hongki KIM, Injo JEONG, Youngjin OH, Jungsoo KIM, Yongsang YUN, Chijeong CHOI, Seonho HAN
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Publication number: 20210015389Abstract: A medical device system is configured to guide implantation of a pacing electrode for left bundle branch pacing. The system includes a medical device having a processor configured to receive at least one cardiac electrical signal, determine a feature of the cardiac electrical signal, compare the feature to left bundle branch signal criteria, and determine a left bundle branch signal in response to the feature meeting the left bundle branch signal criteria. The system includes a display unit configured to generate a user feedback signal indicating advancement of a pacing electrode into a left portion of a ventricular septum in response to the processor determining the left bundle branch signal.Type: ApplicationFiled: July 17, 2020Publication date: January 21, 2021Inventors: Xiaohong ZHOU, Wade M. DEMMER, Robert W. STADLER
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Publication number: 20210015390Abstract: A medical device system is configured to guide implantation of a pacing electrode for left bundle branch pacing. The system includes a medical device having a processor configured to receive at least one cardiac electrical signal, determine a feature of the cardiac electrical signal, compare the feature to left bundle branch signal criteria, and determine a left bundle branch signal in response to the feature meeting the left bundle branch signal criteria. The system includes a display unit configured to generate a user feedback signal indicating advancement of a pacing electrode into a left portion of a ventricular septum in response to the processor determining the left bundle branch signal.Type: ApplicationFiled: August 11, 2020Publication date: January 21, 2021Inventors: Xiaohong ZHOU, Wade M. DEMMER, Robert W. STADLER
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Publication number: 20210015391Abstract: A deep intracranial electrode which comprises a flexible wire, an electrode contact, a connector and a shield sleeve, one end of the flexible wire is connected to the electrode contact, the other end connected to the connector; the shield sleeve sheathes around the flexible wire, a sum of a length of a part of the flexible wire arranged outside the shield sleeve and a length of the shield sleeve being adjustable. When the shield sleeve sheaths around the flexible wire, the length of the flexible wire inside the radio-frequency magnetic field of the magnetic resonance equipment may equal to a sum of the length of the shield sleeve and a length of the flexible wire outside the shield sleeve.Type: ApplicationFiled: August 23, 2019Publication date: January 21, 2021Inventors: Xijun GUAN, Xiaolong MO
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Publication number: 20210015392Abstract: A method for manufacturing a deep intracranial electrode, a bending-resistant deep intracranial electrode and an electroencephalograph is disclosed. The method comprises the following steps: manufacturing a support rod of the deep intracranial electrode with a shape memory alloy material, the shape memory alloy having a preset phase-transformation temperature; subjecting the support rod in a straight state to an annealing process such that the support rod memorizes a straight shape.Type: ApplicationFiled: August 23, 2019Publication date: January 21, 2021Inventors: Xijun GUAN, Xiaolong MO
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Publication number: 20210015393Abstract: An EEG headgear assembly for placement on the head of a subject which includes headgear formed from elastic straps and wired electrodes. The electrodes are secured to the headgear by means of elastic pockets which press an electrode head toward a subjects skin.Type: ApplicationFiled: March 18, 2019Publication date: January 21, 2021Inventors: Kenneth George Jordan, Gary Reasoner
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Publication number: 20210015394Abstract: The present disclosure provides a magnet assembly for a Magnetic Resonance Imaging (MRI) system. The assembly includes a yoke having a frame member movably positioned by a magnet movement unit. A first arm extends laterally from a first end of the frame member and includes a first magnet-pole assembly having a first central axis. A second arm extends laterally from a second end of the frame member and includes a second magnet-pole assembly. The second magnet-pole assembly includes a second central axis and configured to orient towards with the first magnet-pole assembly while maintaining a gap therebetween, for positioning a body portion for magnetization. A first and a second clamp member are each mounted about a peripheral side surface of the magnet-pole assemblies, respectively. The clamp members are configured to attenuate a leakage flux emanating from the magnet pole assemblies.Type: ApplicationFiled: July 18, 2019Publication date: January 21, 2021Inventor: Fengling ZHANG
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Publication number: 20210015395Abstract: A FFL-based magnetic particle imaging three-dimensional reconstruction method includes: acquiring current signal data of an induction coil during FFL-based three-dimensional scanning process of a scanned object; based on the current signal data, performing deconvolution through a preset kernel function to acquire a two-dimensional image data set, wherein the kernel function is a step function with L2 regularized constraint; based on the two-dimensional image data set, acquiring an initial three-dimensional image by using a Wiener filtering deconvolution algorithm; and based on the initial three-dimensional image, performing deconvolution through a Langevin function, and acquiring a final three-dimensional image by Radon transformation.Type: ApplicationFiled: June 22, 2020Publication date: January 21, 2021Applicant: INSTITUTE OF AUTOMATION, CHINESE ACADEMY OF SCIENCESInventors: Jie TIAN, Peng ZHANG, Hui HUI, Kun WANG, Xin YANG
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Publication number: 20210015396Abstract: Provided is an electromagnetic device for magnetic particle imaging, including: a return yoke having a gap, which extends in a Y direction and forms a magnetic field space; a gradient magnetic field generating unit, which is provided to the return yoke, and is configured to generate, in the magnetic field space, a gradient magnetic field in an X direction, and to form, in the magnetic field space, a zero-field region extending in the Y direction; an alternating magnetic field generating unit, which is provided to the return yoke, and is configured to generate an alternating magnetic field in the magnetic field space; and a rotation mechanism configured to rotate the gradient magnetic field and the alternating magnetic field relative to a subject with a Z direction being a rotation axis.Type: ApplicationFiled: March 5, 2019Publication date: January 21, 2021Applicant: Mitsubishi Electric CorporationInventor: Tetsuya MATSUDA
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Publication number: 20210015397Abstract: Methods and apparatus for predicting/estimating the dry weight of an individual, e.g., a patient undergoing dialysis treatment, are provided. The techniques employ a bioimpedance measurement (303) on the individual's calf (101) to obtain information regarding the extracellular fluid volume of the calf Using a measurement of the calfs circumference (309), a resistivity value is calculated, normalized by the individual's body mass index (BMI), and then offset by a reference value to obtain a new variable, ?nRho, which is shown, by comparison with a “gold standard” (FIGS. 5-9), to be highly effective in predicting/estimating dry weight (FIGS. 10-13 and 15-16). The techniques are easy to use and provide accurate dry weight predictions/estimations without substantially adding to the complexity or cost of dialysis procedures. The techniques can also be used for individuals who are not renal patients, e.g.Type: ApplicationFiled: September 25, 2020Publication date: January 21, 2021Inventors: Nathan W. Levin, Fansan Zhu
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Publication number: 20210015398Abstract: Various embodiments are described herein for a device, system, and method for identifying a location of an ingestible device within a gastrointestinal tract of a body. In some embodiments, the ingestible device includes a sensing unit with an axial optical sensing sub-unit located proximal to at least one end of the device, and a radial optical sensing sub-unit located proximal to a radial wall of the device, and may autonomously identify a location within the gastrointestinal tract. In some embodiments, the ingestible device includes optical illumination sources and detectors that operate at a plurality of different wavelengths, and may discern regions of a gastrointestinal tract by using the reflection properties of organ tissue and occasional particulates. In some embodiments, the ingestible device may sample fluid or release medicament based on a detected device location.Type: ApplicationFiled: September 24, 2020Publication date: January 21, 2021Inventors: Mitchell Lawrence Jones, Alain Labbé, Mark Sasha Drlik, Christian Terry Proch McMechan
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Publication number: 20210015399Abstract: A method for measuring levels of specific biomarkers in exhaled breath. Specific compounds such as nitric oxide and isoprene can be monitored from a subject's breath. The resultant measurements can provide indications of the subject's medical condition, or response to an applied stress.Type: ApplicationFiled: July 17, 2020Publication date: January 21, 2021Applicant: Ohio State Innovation FoundationInventor: Pelagia I. Gouma
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Publication number: 20210015400Abstract: Apparatus and methods are described including a surface (62) configured to receive an arm of a patient. A first sensor (66) is operatively coupled to the surface (62) and is configured to (a) detect movement of the surface (62), pressure exerted upon the surface (62), and/or force exerted upon the surface (62), and (b) generate a first sensor signal in response thereto. A computer processor (72) receives the first sensor signal, and derives a respiratory rate of the patient at least partially based upon the received first sensor signal. Other applications are also described.Type: ApplicationFiled: March 21, 2019Publication date: January 21, 2021Inventors: Daniel Glozman, Zev Sohn, Yonatan Amir
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Publication number: 20210015401Abstract: A respiratory function testing system includes an air transforming device, a sound reception device and an operation device. The air transforming device is configured to collect exhaled and/or inhaled air for a predetermined period and generate a wide frequency range sound signal according to the collected respired air. The wide frequency range sound signal at least contains an ultrasonic signal. The sound reception device is configured to receive and record the wide frequency range sound signal as an audio file. The operation device is in communication with the sound reception device and is configured to receive and compute the audio file to generate a respiratory function parameter. Besides, the recorded wide frequency range sound signal may be converted into a spectrogram for further applications, and the computation of the audio file can be replaced by analyzing the spectrogram. A respiratory function testing method corresponding to the respiratory function testing system is also provided.Type: ApplicationFiled: October 5, 2020Publication date: January 21, 2021Inventors: Chia-Chi SU, Hsiao-Pao YEN, Pei-Ling HSU, Chia-Hung CHEN
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Publication number: 20210015402Abstract: Design and development of an affordable, user-friendly, and portable POCT hand tremor detection device has been reported. This device is composed of a detection unit, a flexible pressure sensor, a signal processing unit, and a power supply. The detection unit is composed of the sensor and press-knob. The flexible pressure sensor is a combination of usually spaced apart flexible polymer preferably polydimethylsiloxane, flexible substrate preferably paper, and a conductive coating preferably reduced graphene oxide (RGO). When the users put pressure on the press-knob through the fingers, the flexible pressure sensor actuates and bends so that conductive RGO layers on the flexible substrates come in contact with each other to generate an output current.Type: ApplicationFiled: August 29, 2017Publication date: January 21, 2021Applicant: INDIAN INSTITUTE OF TECHNOLOGY, GUWAHATIInventors: Mitradip BHATTACHARJEE, Dipankar BANYOPADHYAY, Sunny KUMAR
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Publication number: 20210015403Abstract: The invention relates to a method (400) performed by an anesthetizing monitoring unit (110) configured to determine an anesthetized patient state, the method comprising disabling (410) an input port (111) of the anesthetizing monitoring unit (110), transmitting (420) a stimuli signal (Sstimuli) using an output port (112) of the anesthetizing monitoring unit (110), enabling (430) the input port (111) of the anesthetizing monitoring unit (110) with a delay (?T) relative to the transmission of the stimuli signal (Sstimuli), receiving (440) an evoked electromyography, EMG, response signal (SResponse) in response to the transmitted stimuli signal (Sstimuli), determine (450) an anesthetized patient state by determining a neuromuscular function value using properties of the stimuli signal (Sstimuli) and the response signal (SResponse). The invention further relates to an anesthetizing monitoring unit (110) and an anesthetizing monitoring system (100).Type: ApplicationFiled: March 11, 2019Publication date: January 21, 2021Inventor: John Martyn GRAY
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Publication number: 20210015404Abstract: One embodiment of the present invention provides a method comprising running a monitoring agent on a connected electronic device, and determining, via the monitoring agent, a level of hearing impairment of an individual user associated with the connected electronic device. The method further comprises, in response to determining the individual user has some level of hearing impairment, selecting a notification mechanism suitable for notifying the individual user based on the level of hearing impairment, and invoking the monitoring agent to notify the individual user of an event in accordance with the notification mechanism selected.Type: ApplicationFiled: July 15, 2019Publication date: January 21, 2021Inventors: Raphael I. Arar, Chris Kau, Jonathan D. Dunne
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Publication number: 20210015405Abstract: An audiometric test method is provided where a noise stress test is applied to a subject, during the application of the noise stress test measuring one or more indicators reflecting a subjects purinergic hearing adaptation to noise exposure. The measured indicators are analysed to quantify degree of change and rate of change of the subjects purinergic hearing adaptation to noise exposure. An audiometric test system and audiometer configured to perform the test is also provided.Type: ApplicationFiled: March 6, 2019Publication date: January 21, 2021Inventors: Gary David HOUSLEY, Jennie M.E. CEDERHOLM
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Publication number: 20210015406Abstract: In some examples, a sensor holder device is described. The sensor holder device may include a rigid body, a set legs attached to the rigid body, a sensor guiding structure, a sensor retaining structure, and an electrical trace. The sensor retaining structure may be sized to accommodate a sensor wire. The electrical trace may extend proximate the sensor retaining structure and along one of the legs.Type: ApplicationFiled: September 30, 2020Publication date: January 21, 2021Inventors: William Biederman, Timothy Stowe
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Publication number: 20210015407Abstract: Various examples are directed to a glucose sensor comprising a working electrode to support an oxidation reaction and a reference electrode to support a redox reaction. The reference electrode may comprise silver and silver chloride. The Glucose sensor may also comprise an anti-mineralization agent positioned at the reference electrode to reduce formation of calcium carbonate at the reference electrode.Type: ApplicationFiled: July 15, 2020Publication date: January 21, 2021Inventors: Sebastian Bohm, Wenjie Lan, Thomas Robert Porter, Daiting Rong, Jason Halac
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Publication number: 20210015408Abstract: A regional oximetry pod drives optical emitters on regional oximetry sensors and receives the corresponding detector signals in response. The sensor pod has a dual sensor connector configured to physically attach and electrically connect one or two regional oximetry sensors. The pod housing has a first housing end and a second housing end. The dual sensor connector is disposed proximate the first housing end. The housing at least partially encloses the dual sensor connector. A monitor connector is disposed proximate a second housing end. An analog board is disposed within the pod housing and is in communications with the dual sensor connector. A digital board is disposed within the pod housing in communications with the monitor connector.Type: ApplicationFiled: September 30, 2020Publication date: January 21, 2021Inventors: Ammar Al-Ali, Kevin Forrest, David Dalke, Walter M. Weber
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Publication number: 20210015409Abstract: A sensor element (101) for detecting an analyte in a fluid sample by optical probing comprises a translucent membrane (110) with a front side (111) defining a sensor surface for contacting a fluid sample, and a back side (112) facing away from the front side (111). The sensor element (101) has a reflective layer (114) at the front side (111) of the translucent membrane (110). An optical input port (120) is connected to the back side (112) of the translucent membrane (110) for feeding probing light to the translucent membrane (110) through the back side (112). An optical output port (130) is connected to the back side (112) of the translucent membrane (110) for collecting an optical response from the translucent membrane (110) through the backside (112). The sensor element further comprises an optical constriction element (140) with a screen element (141) arranged between the input port (120) and the output port (130), thereby optically separating the output port (130) from the input port (140).Type: ApplicationFiled: April 8, 2019Publication date: January 21, 2021Inventor: Thomas KJAER
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Publication number: 20210015410Abstract: Sensors can be used for the detection of an analyte concentration, such as an electrolyte and/or a blood gas. In some embodiments, such sensors can include a matrix material, a nanoparticle associated with the matrix material, and a signaling molecule associated with the nanoparticle. In particular embodiments, the signaling molecule can exhibit a fluorescence emission intensity as a function of the analyte concentration.Type: ApplicationFiled: July 17, 2019Publication date: January 21, 2021Inventor: Christopher F. Grant
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Publication number: 20210015411Abstract: An apparatus for insertion of a medical device in the skin of a subject is provided.Type: ApplicationFiled: September 25, 2020Publication date: January 21, 2021Inventors: Phillip Yee, Christopher A. Thomas, Udo Hoss, Lei He, Michael R. Love
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Publication number: 20210015412Abstract: A vacuum assisted lancing system can include a tubular body having a vacuum chamber, a lancing mechanism configured to removably couple with a lance, a vacuum mechanism including a piston slideably coupled within the body, a release mechanism for selectively holding the vacuum mechanism in an energized state and an opening for allowing fluid communication between the vacuum chamber and an atmosphere. A method of manipulating a surface for blood extraction can include coupling a lancing system to the surface, blocking an opening, creating a vacuum, moving a lance coupler from a first position distal from the surface to a second position proximal to the surface, maintaining the vacuum for a period of time and commencing dissipation of the vacuum by unblocking the opening.Type: ApplicationFiled: September 24, 2020Publication date: January 21, 2021Inventor: Christopher A. Jacobs
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Publication number: 20210015413Abstract: Articles and methods for collecting and/or facilitating transfer of fluids are generally provided. In some embodiments, an article comprises a fluid collection region for introducing a fluid, such as a sample (e.g., blood sample) or a reagent, into a fluidic system. The articles and methods described herein may be useful for facilitating the filling of relatively small channels with a fluid, such as channels of a microfluidic device. The articles and methods may, for example, interface with a patient sample (e.g., a droplet of blood), or with a macroscopic fluid source such as a pipette or syringe. In certain embodiments, articles and methods described herein may increase the ease of collecting a fluidic sample from a patient, prevent or reduce spillage of the fluidic sample, reduce contamination of a fluidic sample, and/or prevent or reduce air from entering a fluidic sample or device compared to certain existing fluid collection devices.Type: ApplicationFiled: October 2, 2020Publication date: January 21, 2021Applicant: OPKO Diagnostics, LLCInventors: Jason Taylor, Hardeep Singh, Matthew Dirckx
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Publication number: 20210015414Abstract: Blood sample collection and processing system (1) using a tube (102) and a holder (104) is described herein. The tube (102) includes a plasma separation system (114) for converting a whole blood sample (129) into a plasma sample without using centrifugation. The plasma separation system (114) may comprise a filtration system such as a hollow fiber element (115). The tube (102) is thereafter placed in the holder (104) for analysis regarding the plasma. The results of the analysis may be displayed to the user via a display screen (134) to allow the user to determine whether the sample is sufficient for further use. Inasmuch as the analysis system (132) performs a rapid analysis of the plasma sample, the patient may still be present or in close proximity and if the sample is insufficient, the healthcare provider can take another whole blood sample (129), counsel the client regarding the blood sample (129), or examine the patient further.Type: ApplicationFiled: July 17, 2020Publication date: January 21, 2021Inventors: David L. YANG, Fiona S. ADAIR, Dirk HECKEL
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Publication number: 20210015415Abstract: Methods and systems are provided herein for monitoring a user's well-being. The methods may comprise collecting one or more sensor data, analyzing at least a subset of the collected sensor data, extracting features from the collected and/or analyzed sensor data, and determining one or more of a physical score, a psychological score and a total score. The methods may further comprise determining a user's well-being based on one or more of the scores.Type: ApplicationFiled: June 9, 2020Publication date: January 21, 2021Inventors: Eran Ofir, Uri Schatzberg
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Publication number: 20210015416Abstract: A method for evaluating a multi-modal emotion cognition capability of a patient with an autism spectrum disorder, mainly includes the following steps: (1) setting a multi-modal evaluation environment, where the multi-modal evaluation environment is used to stimulate a tested object; and the multi-modal evaluation environment includes: a visual scene, a verbal communication scene, and an emotional communication scene; (2) collecting multi-modal evaluation information, where the evaluation information includes: intelligence information, behavioral data, and eye movement data of the tested object; and (3) performing statistical analysis, to obtain an emotion cognition capability of the tested object, where the performing statistical analysis includes: performing statistical analysis on the behavioral data, performing statistical analysis on the eye movement data, and performing statistical analysis on a combination of the behavioral data and the eye movement data.Type: ApplicationFiled: November 11, 2019Publication date: January 21, 2021Applicant: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGYInventors: Lan WANG, Nan YAN, JianYing WANG, Qi SU
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Publication number: 20210015417Abstract: The present invention relates to a computer implemented method for training one or more parameters of a model. More particularly, the present invention relates to a computer implemented method for training one or more parameters of a model based on emotion signals. Aspects and/or embodiments seek to provide a computer implemented method which can calculate and/or predict emotion signals for training software implementations of mathematical models or machine learned models based on these emotion signals.Type: ApplicationFiled: March 21, 2019Publication date: January 21, 2021Inventors: Ross Edward Francis Harper, Sebastiaan De Vries
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Publication number: 20210015418Abstract: [Overview] [Problem to be Solved] To grasp a contact pressure on a first sensor with a surface of a living body and reduce its influence on the quality of a signal obtained by the first sensor. [Solution] There is provided an information processing system including: a sensor section including a first sensor that detects information for judging an emotion of a living body and a second sensor that detects a body motion pressure of a region of the living body corresponding to a detection region of the first sensor; and a correction processing section that corrects first sensor information obtained by the first sensor on the basis of second sensor information obtained by the second sensor. This makes it possible to grasp a contact pressure on the first sensor with a surface of the living body and reduce its influence on the quality of a signal obtained by the first sensor.Type: ApplicationFiled: February 21, 2019Publication date: January 21, 2021Inventor: MASAYOSHI MORITA