Abstract: The present invention generally relates to systems and methods for delivering and/or withdrawing a substance or substances such as blood or interstitial fluid, from subjects, e.g., from the skin and/or from beneath the skin. In one aspect, the present invention is generally directed to devices and methods for withdrawing or extracting blood from a subject, e.g., from the skin and/or from beneath the skin, using devices containing a fluid transporter (for example, one or more microneedles), and a storage chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In some cases, the device may be self-contained, and in certain instances, the device can be applied to the skin, and activated to withdraw blood from the subject. The device, in some cases, may be interfaced with external equipment to determine an analyte contained within a fluid contained within or collected by the device.

Abstract: The presently disclosed subject matter relates to a play environment for children and infants for detecting motor delays or impairments, evaluating neurological development, and for diagnosing developmental disorders, and methods and systems of using the same.

Abstract: The present invention relates to a three-dimensional adhesive device to be attached to the body surface of a mammal comprising a microelectronic sensing system 5 characterized by (a) a three-dimensional adhesive body made of a pressure sensitive adhesive having an upper surface and a bottom surface; (b) a microelectronic system embedded in the body of the pressure sensitive adhesive; 10 (c) one or more cover layer(s) attached to the upper surface; and (d) optionally a release liner releasable attached to the bottom surface of the adhesive device. Suitably the microelectronic system is a microelectronic sensing system capable of 15 sensing physical input such as pressure, vibration, sound, electrical activity (e.g. from muscle activity), tension, blood-flow, moisture, temperature, enzyme activity, bacteria, pH, blood sugar, conductivity, resistance, capacitance, inductance or other chemical, biochemical, biological, mechanical or electrical properties.

Abstract: In one embodiment, an electrical activity measurement system includes a catheter to be inserted into a body part and including at least one electrode, signal processing circuitry coupled to receive an intracardiac electrogram (IEGM) signal from the at least one electrode and process the IEGM signal for output to a recording apparatus via a cable, which picks up surrounding electrical noise, and feedback circuitry configured to receive at least some of the electrical noise picked up by the cable, and provide a feedback signal indicative of the received electrical noise to the signal processing circuitry, which is configured to compensate at least partially for the electrical noise, which is not yet in the IEGM signal but will be added to the IEGM signal in the cable, responsively to the feedback signal to produce a noise-compensated IEGM signal for output to the recording apparatus via the cable.

Abstract: A system and method for providing diagnostic analysis of a physical condition of a human body. A signal generator, an emitter, a receiver, and processor(s) generate a baseline signal. In some implementations, the emitter may emit the baseline signal through cells of the human body over scanning points for a predetermined amount of time, and a receiver detects reflected signals that have propagated through the cells of the human body. Some implementations include determining, by the one or more processors, a power spectrum density (PSD) of the reflected baseline signal and a spectral variance in the PSD of the reflected baseline signal relative to the baseline signal. Some implementations may compare the spectral variance to one or more predetermined spectral variances corresponding to one or more conditions of the human body and determine the condition of the human body, based on the comparison.

Abstract: Provided are conformable devices to measure subdermal fluid flow and related methods. A soft, stretchable and flexible substrate supports a thermal actuator and various specially positioned temperature sensors. A microprocessor in electronic communication with sensors calculates subdermal fluid flow from the measured upstream and downstream temperatures, as well as various application-dependent parameters. Devices and methods provided herein are particularly useful for measuring cerebral spinal fluid in a ventricular shunt placed for treatment of hydrocephalus.

Abstract: Embodiments described herein relate to an analyte monitoring device having a user interface with a display and a plurality of actuators. The display is configured to render a plurality of display screens, including a home screen and an alert screen. The home screen is divided into a plurality of simultaneously displayed panels, with a first panel displays a rate of change of continuously monitored analyte levels in interstitial fluid, a second panel simultaneously displays a current analyte level and an analyte trend indicator, and a third panel displays status information of a plurality of components of the device. When an alarm condition is detected, the display renders the alert screen in place of the home screen, the alert screen displaying information corresponding to the detected alarm condition. Furthermore, the actuators are configured to affect further output of the analyte monitoring device corresponding to the detected condition.

Abstract: A method for generating a diagnosis via a digital health application includes receiving, by a digital health application, a request for a diagnosis. A digital health application selects a plurality of questions based on the initial complaint, an order of presenting each of the plurality of questions, the order associated with the plurality of questions. The digital health application displays, to a user of the digital health application, in the associated order, each of the plurality of questions. The digital health application receives user input responsive to the questions. The digital health application determines a diagnosis and modifies a user interface to display an identification of the determined diagnosis. The digital health application requests an indication of whether the user of the digital health application accepts the diagnosis. The digital health application requests an indication of whether to establish a consultation with a medical professional to discuss the diagnosis.

Abstract: A control device includes a control unit and a determination unit. The control unit controls an operation of radiation tubes such that radiation is emitted at irradiation positions whose number is smaller than the total number of irradiatable positions preset so as to correspond to irradiation angles. The determination unit determines whether or not the radiation needs to be additionally emitted at the irradiatable positions different from the irradiation positions in order to obtain the tomographic image with an image quality level required for diagnosis, on the basis of a determination image obtained by the emission of the radiation at the irradiation positions.

Abstract: A control device includes a detection unit, a determination unit, a generation unit, and a control unit. The detection unit detects a state of each of the plurality of radiation tubes in a case in which tomosynthesis imaging that continuously irradiates an object with radiation at a plurality of different irradiation angles in order to generate a tomographic image in any tomographic plane of the object is performed using the plurality of radiation tubes. The determination unit determines whether or not to permit the generation of the tomographic image on the basis of the detection result of the detection unit and outputs a determination result. The generation unit generates the tomographic image. The control unit controls the operation of the generation unit on the basis of the determination result.

Abstract: An imaging system includes a first portion and a second portion that translates and/or rotates with respect to the first portion. A first locking mechanism may prevent the second portion from translating with respect to the first portion, such as during transport of the system. A second locking mechanism may prevent the second portion from rotating with respect to the first portion, such as during transport and/or during an imaging scan. Further embodiments include a cable management system between the first and second portions, a spherically-shaped surface of a support gimbal and a user interface device for an imaging system.

Abstract: A method and system for using in a Positron Emission Tomography (PET) system. The PET system comprises at least one processor and a storage. The PET system comprises an acquisition module and a processing module. The acquisition module is configured to acquire a PET data set corresponding to a target object. The acquisition module comprises a first light sensor array, a second light sensor array, and a scintillator array. The processing module is configured to determine a three-dimensional position of an incidence photon based on the PET data set. The first number of light sensors in the first light sensor array and the second number of light sensors of the second light sensor array is less than the number of scintillator of the scintillator array.

Abstract: Methods for detecting positional movement of orthopedic implants are described herein. In one embodiment, the method may include receiving a two-dimensional image defining an image plane, the two-dimensional image capturing a reference marker received within the bone and an orthopedic implant received within a bone, calculating a first angle of the reference marker relative to the image plane based on previously stored dimensions of the reference marker, calculating a second angle of the orthopedic implant relative to the image plane based on previously stored dimensions of the orthopedic implant, comparing the first angle to the second angle to calculate a current angle of rotation, and comparing the current angle of rotation to a previously calculated angle of rotation to detect rotation of the orthopedic implant relative to the bone.

Abstract: Disclosed is a linear array ultra-fast scanning x-ray imaging device. The linear array x-ray imaging device is single photon sensitive, operating in frame output mode and including a pixel array Application Specific Integrated Circuit including the readout pixel array. The ASIC includes digital control logic and sufficient memory to accumulate digital output frames in various modes of operation prior to output from the ASIC, permitting advanced imaging functionalities directly on the ASIC, while maintaining a dynamic range of 16 bits and single photon sensitivity. The effective or secondary frames output from the pixel array ASIC can be tagged with user provided external triggers synchronizing the effective frames to the x-ray beam energy and/or to the movement of the x-ray source or imaged object. This enables dual energy imaging and ultra-fast scanning, without complex and costly conventional photon counting x-ray imaging sensors. The system architecture is simpler and higher performance.

Abstract: Various aspects include methods for compensating for the effects of charge sharing among pixelate detectors in X-ray detectors by applying a correspondence factor to counts of X-ray photons in energy bins to estimate incident X-ray photon energy bins. The correspondence factor may be determined by determining an incident X-ray photon energy spectrum, adjusting the incident X-ray photon energy spectrum to account for an energy resolution of the pixelated detector, generating a charge sharing model for the adjusted incident X-ray photon energy spectrum based on a percentage charge sharing parameter of the pixelated detector, applying the charge sharing model to energy bins of the pixelated detector to estimate counts in each of the energy bins, and determining the correspondence factor by comparing the estimated counts in each of the energy bins to counts in the energy bins that would be expected for the adjusting the incident X-ray photon energy spectrum.

Abstract: A mobile radiography apparatus includes a moveable transport frame and an adjustable support arm attached thereto to support an x-ray source. At least one digital detector storage slot in the transport frame is configured to receive and to controllably lower at least one portable radiographic detector into the slot at a controlled speed.

Abstract: A system and method for determining kinetic parameters associated with a kinetic model of an imaging agent in a liver is provided. An image reconstruction device can receive radiotracer activities corresponding to a predetermined time period. For example, these radiotracer activities can include PET scan data corresponding to a number of time frames. The radiotracer activities can be used to determine a liver time activity curve and a circulatory input function. The liver time activity curve and circulatory input function can be used along with a kinetic model of the liver to produce kinetic parameters. These kinetic parameters can be used to determine hepatic scores, such as a hepatic steatosis score, a hepatic inflammation score, and a cirrhosis score. These scores are indicative of diseases of the liver, including nonalcoholic fatty liver disease, nonalcoholic steatohepatitis, and hepatic fibrosis.

Abstract: A controller for maintaining alignment of X-Ray imagery and ultrasound imagery includes a memory that stores instructions, and a processor that executes the instructions. When executed by the processor, the instructions cause the controller to execute a process that includes receiving data from an X-Ray system used to perform X-Ray imaging, and receiving data from an ultrasound imaging probe used to perform ultrasound imaging. The process executed by the controller also includes registering imagery based on X-Rays to imagery from the ultrasound imaging probe based on an X-Ray image of the ultrasound imaging probe among the imagery based on X-Rays, and detecting, from the data from the ultrasound imaging probe, movement of the ultrasound imaging probe.

Abstract: When an irradiation range control member is reflected in a region of interest, a control unit of an X-ray fluoroscope is configured to perform at least one of a first control to update a region of interest to a new region of interest by excluding a portion where the irradiation range control member is reflected in the region of interest and a second control to assign a predetermined pixel value to a pixel of a portion where the irradiation range control member is reflected in the region of interest.

Abstract: Disclosed herein is a method comprising: obtaining a third image from a first X-ray detector when the first X-ray detector and a second X-ray detector are misaligned; determining, based on a shift between a first image and the third image, a misalignment between the first X-ray detector and the second X-ray detector when the first and second detectors are misaligned; wherein the first image is an image the first X-ray detector should capture if the first and the second detectors are aligned.

Abstract: According to certain described aspects, an acoustic sensor is employed in a variety of beneficial ways to provide improved physiological monitoring, among other advantages. In various embodiments, the acoustic sensor may include an attachment sub-assembly including a deformable portion that enables improved coupling to a patient. Additionally, the acoustic sensor may include an adhesive layer that, in combination with the deformable portion, enables even, robust, and secure attachment of the sensor to the patient. In various embodiments, an acoustic coupler having a semi-spherical shape is provided to further improve coupling of acoustic signals from the patient to the sensor.

Abstract: The present invention aims to obtain and provide one or more types of information desired by an operator with a high efficiency. From a probe that transmits an ultrasonic wave to a subject and receives the ultrasonic wave coming from the subject due to the transmission, a reception signal is received and the reception signal is processed. Accordingly, a movement vector indicating a movement amount and a movement direction is calculated and a movement vector distribution is determined for a plurality of points set at least two-dimensionally in the subject. A distribution of one or more desired movement vector components is extracted from the movement vector distribution.

Abstract: Disclosed herein is a system and method for characterizing adventitial tissue. In one aspect, a system and method are disclosed that characterizes tissue types within the adventitial tissue including nerve bundles and blood vessels. In a further aspect, the adventitia is imaged and characterized to provide guidance for crossing lesions within an occluded vessel.

Abstract: The ultrasound diagnostic apparatus, ultrasound image generation apparatus and method transmit ultrasound waves to a subject into which a puncture tool is inserted, receive reflected waves reflected from the subject and the puncture tool, and generate echo signals of time-sequential frames based on the received reflected waves, and generate an ultrasound image of the subject based on the generated echo signals. These apparatus and method generate a differential echo signal between time-sequential frames from the echo signals, perform a tip detection process based on the differential echo signal to thereby detect at least one tip candidate including a tip end of the puncture tool, highlight a tip candidate of the puncture tool detected to thereby generate a tip image, and display the tip image of the highlighted puncture tool so as to be superimposed on the generated ultrasound image.

Abstract: To provide an ultrasonic CT apparatus that can change an inclination of a side surface of a breast such that an ultrasonic wave is incident on a surface of an entire circumference of the breast at an angle close to perpendicular, and that has less psychological burden on a subject. A container provided with an opening to which the breast is inserted is disposed below a bed provided with a through hole to which the breast of the subject is inserted. In the container, a member that propagates or transmits the ultrasonic wave is disposed, and the member is relatively pressed against a side surface or a nipple portion of the breast such that an inclination of the side surface of the breast is close to perpendicular. A transducer array emits the ultrasonic wave around the breast with the inclination of the side surface being close to perpendicular.

Abstract: An imaging device includes a two dimensional array of piezoelectric elements. Each piezoelectric element includes: a piezoelectric layer; a bottom electrode disposed on a bottom side of the piezoelectric layer and configured to receive a transmit signal during a transmit mode and develop an electrical charge during a receive mode; and a first top electrode disposed on a top side of the piezoelectric layer; and a first conductor, wherein the first top electrodes of a portion of the piezoelectric elements in a first column of the two dimensional array are electrically coupled to the first conductor.

Abstract: An imaging device includes a two dimensional array of piezoelectric elements. Each piezoelectric element includes: a piezoelectric layer; a bottom electrode disposed on a bottom side of the piezoelectric layer and configured to receive a transmit signal during a transmit mode and develop an electrical charge during a receive mode; and a first top electrode disposed on a top side of the piezoelectric layer; and a first conductor, wherein the first top electrodes of a portion of the piezoelectric elements in a first column of the two dimensional array are electrically coupled to the first conductor.

Abstract: An ultrasound imaging system (10) comprising probe (20), a processing unit (30) for processing an image, a display (50) for visualizing the image, and a control panel (40) for configuring and controlling the processing unit. The control panel comprises input control elements (41) and a touch pad (42). The touch pad is a multi-touch device providing multi-touch information of at least two or more touch of user on the touch pad for determining a gesture and an associated system function.

Abstract: A system for characterizing tissue includes a probe that delivers a continuous and periodic mechanical vibration to a tissue of a subject; an ultrasound emitter that emits a sequence of ultrasound shots and an ultrasound receiver that receives corresponding echo signals to track how the tissue is moved by the periodic mechanical vibration delivered to the tissue; and a control module programmed to provide homogeneity information to an operator of the system, the homogeneity information being determined from at least some of the echo signals and being representative of the ability of the tissue to transmit elastic waves and of the homogeneity of the tissue with respect to the propagation of elastic waves.

Abstract: A Method for tissue characterization by ultrasounbd wave attenuation measurements comprising: a) transmitting at least an ultrasound pulse in a target body; b) receiving the ultrasound waves reflected by the said target body and transforming the said reflected ultrasound pulses in RF reception signals; c) extracting the envelope of the received RF signals; d) carrying out a logarithmic compression of the said extracted envelope and e) computing the propagation depth dependent attenuation coefficient of the tissues crossed by the ultrasound pulse in the target body as the slope of the line fitting the said logarithmic compressed envelope data along the penetration depth of the ultrasound pulse in the said target body. The invention relates also to an ultrasound system for carrying out said method.

Abstract: An ultrasound elastography method and system are provided. The method may include: exciting an ultrasound probe to transmit ultrasound waves to a body tissue under examination and receive ultrasound echoes to obtain a first ultrasound echo signal, wherein the ultrasound probe comprises an ultrasound transducer provided with multiple array elements; obtaining an ultrasound image of a body tissue under examination; displaying the ultrasound image; generating a shear waves within the body tissue under examination; exciting array elements of a ultrasound transducer to transmit the ultrasound waves to form an ultrasound beam covering a first area within the body tissue under examination; receiving the ultrasound echoes from the first area to obtain the second ultrasound echo signal; and obtaining the propagation path of the shear waves within the first area according to the second ultrasound echo signal.

Abstract: Ultrasound imaging methods and ultrasound imaging devices are provided, in which an inter-frame processing may be performed on elasticity echo data or the elasticity images to obtain new elasticity images, thereby improving the display frame rate of the elasticity images. The elasticity echo data comprises an ultrasound echo of an ultrasound wave returned from an object, and the elasticity images comprises at least two frames and obtained according to the elasticity echo data.

Abstract: This disclosure relates generally to bio-signal detection, and more particularly to method and system for non-contact bio-signal detection using ultrasound signals. In an embodiment, the method includes acquiring an in-phase I(t) baseband signal and a quadrature Q(t) baseband signal associated with an ultrasound signal directed from the sensor assembly towards the target. Magnitude and phase signals are calculated from the in-phase and quadrature baseband signals, and are filtered by passing through a band pass filter associated with a predefined frequency range to obtain filtered magnitude and phase signals. Fast Fourier Transformation (FFT) of the filtered magnitude and phase signals is performed to identify frequency of dominant peaks of spectrum of the magnitude and phase signals in the ultrasound signal. Value of the bio-signal associated with the target is determined based on weighted values of the frequency of the dominant peaks of the magnitude and phase signals.

Abstract: Ultrasound image devices, systems, and methods are provided. An ultrasound imaging system, comprising an intraluminal imaging device configured to be positioned within a body lumen of a patient, the intraluminal imaging device comprising a rotatable, flexible elongate drive cable; and an ultrasound transducer disposed at a distal portion of the drive cable, the ultrasound transducer configured to transmit ultrasound energy into the body lumen and to receive ultrasound echoes associated with the body lumen; and a processor circuit in communication with the intraluminal imaging device and configured to receive, from the ultrasound transducer, signal data corresponding to the received ultrasound echoes; normalize the signal data; remove a low frequency signal component from the normalized signal data; determine a displacement for one or more scanlines of the signal data after removing the low frequency signal component; and generate an image of the body lumen based on the displacement.

Abstract: Systems and methods are provided for objective, noninvasive staging of diffuse liver disease, and other diseases, from ultrasound shear wave elastography (“SWE”). A liver fibrosis staging SWE image analysis algorithm or toolkit may be used to detect the presence of liver disease and may integrate demographic, clinical, laboratory, conventional sonographic, SWE data, and the like into a combined disease diagnosis decision support model, such as for the diagnosis of high risk liver disease. Advanced image processing methods may be used to extract fibrosis pattern information from SWE and ultrasound (US) image data and this can be used to augment stiffness-based liver fibrosis staging methods.

Abstract: An ultrasound scanner in a spectral Doppler mode, in which a corresponding two-dimensional (2D) ultrasound imaging mode (e.g., B-mode) image is frozen, is switched temporarily to the 2D-mode in response to a continuous contact on a touchscreen. During the continuous contact, the spectral Doppler mode is interrupted, the 2D-mode image becomes live, and the gate for the spectral Doppler mode may be adjusted by a movement of the continuous contact on the touchscreen. Upon termination of the continuous contact, the system reverts back to the spectral Doppler mode, which now operates within the adjusted gate, and the 2D-mode image is frozen. A brief contact may be used to check the position of the gate against a live 2D-mode image without adjusting it.

Abstract: A method for isolating and storing follicular content, including: repeatedly collecting follicular content including an oocyte and follicular fluid (FF) from a plurality of follicles of a female subject during a single oocyte retrieval process; storing each oocyte and follicular fluid originating from the same follicle in a separate storage compartment from the rest of the collected follicular content.

Abstract: A robotic surgical system includes a hydraulic drive system and a surgical instrument removably positioned in operative engagement with the hydraulic drive system.

Abstract: A kit for extracting a tissue specimen includes a specimen container having a proximal rim and a specimen bag operably supported about the proximal rim and depending therefrom. The specimen bag includes a plurality of ribs depending from the proximal rim having a series of mechanical interfaces associated therewith and extending therealong. The kit also includes a cutting guard having a body with proximal and distal ends. The distal end is configured for insertion within the specimen bag when disposed within an incision and the proximal end defines an opening therein configured to facilitate introduction of one or more surgical instruments therethrough. The cutting guard includes one or mechanical interfaces operably associated with the body of the cutting guard configured to selectively engage one of the series of mechanical interfaces of one of the plurality of ribs of the specimen container upon insertion of the cutting guard within the incision.

Abstract: A fastening mechanism that comprises an actuator, a fastening device attached to a distal end of the actuator, and a device coupler, wherein the fastening device is pivotally attached to the device coupler.

Abstract: A device for retracting or opening and closing a tissue wound employs two or more retractor arms that do not enter or penetrate into the wound or incision. The retractor arms engage the tissue on either side of the wound and apply outward or inward pressure on the tissue surface to open or close the wound.

Abstract: A surgical tool (1) for laparoscopic insertion into a subject (13), the tool being expandable from a smaller collapsed configuration to a larger deployed configuration, the tool comprising an extendable barrier (5), and an expandable support (3) that is coupled to the barrier (5); wherein expansion of said support (3) extends said barrier (5).

Abstract: A surgical system includes: an overtube including a channel into which an endoscope is inserted; and an expansion device configured to ensure a surgical space by expanding an interior of a body at a distal side relative to a tip of the overtube. The expansion device includes a sheath and a wire configured to be protrudable from the sheath. The wire is configured to be switchable between a first configuration in which the wire protrudes from the sheath and a second configuration in which the wire protrudes from the sheath in a state where the wire is tilted, around a longitudinal axis, at an angle different from the first configuration.

Abstract: Various methods and devices are provided for allowing multiple surgical instruments to be inserted into sealing elements of a single surgical access device. The sealing elements can be movable along predefined pathways within the device to allow surgical instruments inserted through the sealing elements to be moved laterally, rotationally, angularly, and vertically relative to a central longitudinal axis of the device for ease of manipulation within a patient's body while maintaining insufflation.

Abstract: Surgical anchor assemblies and method of tissue repair using the same. The surgical anchor assemblies have a cannulated fixation device, an implant configured to be coupled to the fixation device, and a stop mechanism for preventing relative movement between the fixation device and the implant, such that the fixation device and the implant are configured to rotate together, and a flexible strand winds up to reduce any slack in the flexible strand used for the repair.

Abstract: The devices and methods can provide short-term strength and rigidity and long-term stability and support after a bone and/or ligament injury in a single procedure. An orthopedic fixation device may include a body having a first end, a second end, and a length therebetween. The body may include a first portion, a second portion and a shaft portion disposed between the first portion and the second portion. The shaft portion may include one or more bioabsorbable materials. The body may include an internal channel disposed along the length. The device may also include a suture being disposed within the internal channel.

Abstract: The technical problem to be solved by the present invention is to design a cosmetic surgical method for presenting a deeper or longer philtrum at the lip by adjusting the muscle flaps at the lips and nose. The theoretical basis of this surgical method is a “theory of labionasal muscle tension thread group” summarized from a series of studies with respect to anatomy, biomechanics and clinical surgical verification. According to this theory, the labionasal muscle tension structure is reconstructed by surgical adjustment of the position and direction of the muscle flaps, so as to produce an effect of changing the profile of the “philtrum” and to improve or remodel the “philtrum” as an aesthetic labial structure.

Abstract: A suture transport system is disclosure for placing a flexible member along a tunnel, the system including a means of transporting a flexible member along a tunnel from a first opening in the tunnel through to a second opening at an opposite end of the tunnel, such that the flexible member extends from both the first and second opening. The system also includes a means of capturing a portion of the flexible member at the second opening, to inhibit the flexible member from retracting into the tunnel second opening. The means of capturing includes an aperture for capturing the portion of the flexible member.

Abstract: This disclosure enables various threading devices (e.g., suturing devices) that can sequentially send a plurality of carriers (e.g., needle caps, sleeves) to an object (e.g., animate, inanimate, human tissue, organ tissue, heart tissue) or sequentially receive a plurality of carriers (e.g., needle caps, sleeves) from an object (e.g., animate, inanimate, human tissue, organ tissue, heart tissue). For example, some threading devices can sequentially send some carriers in a relatively rapid succession or some threading devices can sequentially receive some carriers in a relatively rapid succession.

Abstract: Systems and methods for tibial plateau leveling osteotomy (TPLO) are disclosed. According to some embodiments, an osteotomy method may include cutting a tibia with an arcuate cut to separate a tibial plateau of the tibia from a tibial base of the tibia, rotating the tibial plateau relative to the tibial base from a first orientation to a second orientation, and, with the tibial plateau in the second orientation relative to the tibial base, securing an implant to the tibia to secure the tibial plateau to the tibial base. Securing the implant to the tibia may include embedding a first leg of the implant into the tibial base, and embedding a second leg of the implant into the tibial plateau such that the first and second legs apply compression urging the tibial plateau toward the tibial base.