Abstract: A patient support apparatus comprising a patient support deck and a base to support the patient support deck from a ground surface, with a first frame assembly comprising a plurality of wheels to facilitate movement of the base, and a second frame assembly with one or more lift arms coupling the base to the second frame assembly. A load cell assembly to sense weight applied to the first frame assembly by the second frame assembly comprises a load cell support assembly coupled to the first frame assembly, and a load cell element coupled to the second frame assembly and mounted onto the load cell support assembly such that the second frame assembly is movable with respect to the first frame assembly along two axes of translation and is pivotable with respect to the first frame assembly about three axes of rotation.

Abstract: A patient support apparatus for traversing objects supported on ground surfaces. The patient support apparatus comprises a patient support deck, and a base to support the patient support deck from the ground surface. At pair of caster wheel assemblies spaced from each other are coupled to the base for pivoting movement about respective pivot axes cooperating to define a reference plane. A frame guard coupled to the base defines first and second ramp surfaces each disposed at an angle relative to the reference plane. The first ramp surface is arranged to engage objects before they contact one or more of the caster wheels when the patient support apparatus moves in a first direction. The second ramp surface is arranged to engage objects before they contact one or more of the caster wheels when the patient support apparatus moves in an opposite, second direction.

Abstract: A wearable exoskeleton with full or partial body physical feedback system in virtual and augmented reality applications, or in physical fitness applications, including, in aspects, finger, hand, wrist, elbow, shoulder, back, hip, knee, ankle, and foot components, or combinations thereof. The system implements physical feedback, using resistive or restrictive forces, for both the upper and lower portions of the human body. Additionally, the wearable exoskeleton and system are capable of being configured for particular applications including but not limited to virtual and augmented reality, as well as physical fitness and physical therapy applications.

Abstract: A motorized tensioning mechanism for orthotic devices, such as a knee brace, wherein the controls for the motorized tensioning mechanism may be manual, automatic, or a hybrid of both. Sensors associated with the orthotic device may inform the user regarding tension or other aspects of the device, and, in cases, may automatically adjust tension in the motorized tensioning mechanism.

Abstract: A system is described, for rehabilitating the walk comprising an active exoskeleton with a supporting structure for right leg and left leg, bearing and moving structures of femur, tibia and foot of the patient, a weight supporting device for patient and active exoskeleton, the weight supporting device ending with a structure connected to means for supporting exoskeleton and patient, handling means connected to the weight supporting device to allow its movement, means for transmitting to the weight supporting device electric and pneumatic supplies and electric signals for managing, controlling, monitoring and diagnosing the system, a managing system comprising a microprocessor for acquiring and processing data, and managing a motion neuro-rehabilitation session; a weight supporting device for a system for rehabilitating the walk is further described.

Abstract: A device and method for the treatment of newborn babies and more specifically a strap system with pressure bags to provide pressure to the bodies of newborns. The device is designed to simulate natural birth that applies pressure to a birthing infant to trigger cessation of neurosteriods that is simple to use, effective and reliable.

Abstract: Massage devices and associated methods. Massage devices include a frame, a first massage element rotatably supported on a first support member, and a second massage element rotatably supported on a second support member. The first massage element and the second massage element may be separated by a selected separation distance. The massage device may include a separation adjustment mechanism for adjusting the selected separation distance. The separation adjustment mechanism may be configured to be selectively transitioned between a use configuration and an adjustment configuration. Methods of utilizing a massage device to massage a limb may include positioning the limb between a first massage element and a second massage element of the massage device and applying a compressive force to the limb with each of the first massage element and the second massage element.

Abstract: A calf massage module includes: at least one movable shaft inserted into a spring so as to move forward or rearward by the compression and expansion of the spring; a massage module housing having a movable shaft guide part for guiding the movement of the movable shaft; and a moving housing inserted into the massage module housing according to the movement of the movable shaft.

Abstract: A self-massage roller having a bottle, a covering, and, optionally, a removable cap. The bottle provides a vessel for holding liquids. The covering includes a base layer and a plurality of nubs. The base layer overlays the outer surface of the bottle. Each nub in the plurality of nubs protrudes from the base layer in a direction radially away from the outer surface of the bottle. Each nub is a massage element, and the plurality of nubs forms a textured surface for myofascial release of certain muscles of the user. In another version, each nub is attached directly to the outer surface of the bottle without an intervening base layer. In versions with a cap, the cap may include a flip-up spout, or it may have a plunger valve that opens upon pulling the plunger outward and closes upon pushing in the plunger.

Abstract: An apparatus for pelvic floor muscle trigger point therapy is disclosed. The apparatus comprises a wand to facilitate the release of one or more trigger points in a pelvic floor muscle of a patient. The wand comprises a central portion extending between a first end and a second end. The central portion includes a first bend and a second bend wherein the first bend is formed between a first end region and a first central region. The second bend is formed between the first central region and a second central region. The first end is configured to be vaginally insertable while the second end configured to be rectally insertable. A power source in electrical communication with one or more switches to selectively control a vibration element during use.

Abstract: A method comprises generating, by an implantable stimulator, stimulation sessions at a duty cycle that is less than 0.05 and applying, by the implantable stimulator, the stimulation sessions to a patient. The duty cycle is a ratio of T3 to T4. Each stimulation session included in the stimulation sessions has a duration of T3 minutes and occurs at a rate of once every T4 minutes.

Abstract: The container (1), particularly for medical products, pharmaceuticals, cosmetics, food or the like, comprises: an hollow body (2) at least partly compressible defining a chamber (3) for containing a fluid product (4) and provided with a neck (5); a closure element (6) made in a single body piece with the hollow body (2) and provided with an attachment portion (7) which, in a packaging configuration, is associated with the hollow body (2) along a predefined breaking line (8) adapted to allow the separation of the closure element (6) from the hollow body (2) in a configuration of separation in which on the hollow body (2) is formed a dispensing opening (9) of the fluid product (4); a dispensing valve (13) adapted to allow the outflow of the fluid product (4) through the dispensing opening (9); and a return valve (14) adapted to allow the one-way flow of air (15) towards the chamber (3), wherein the return valve (14) comprises filtering means (16) adapted to filter the air (15) entering the chamber (3).

Abstract: Provided are systems and method for dosing a pharmaceutical formulation. These methods and systems can displace the pharmaceutical formulation through a density flow meter, wherein the density flow meter is configured to measure a density of the pharmaceutical formulation. Next, the pharmaceutical formulation can be dosed into preformed molds and the dosing process can be stopped when the density of the pharmaceutical formulation measured by the density flow meter is below a predetermined threshold.

Abstract: The invention relates to an arrangement and a method for preparing a formulation for parenteral nutrition. In more detail the invention relates to a mixing system for parenteral nutrition, comprising at least two containers, wherein the at least two containers form a modular system. The mixing system comprises a septum, which is pierceable by a spike or a needle and a hanger for attaching the mixing system to an infusion rack. A first container comprises a male connector and a second container comprises a female connector, which fit together. First and second container can be coupled together, thereby forming a channel, which enables the passage of liquid and the mixing of the ingredients of the containers.

Abstract: Systems and methods for detecting administration of a dose of a medicament are described. A medicament dispensing system may include a cap sensor to detect removal of a cap from a container holding a medicament, an orientation sensor to detect an orientation of the container, and a force sensor to detect application of forces to the container. The system may determine that a dose has been administered based on detection of, in order, removal of the cap, movement of the container to an administration orientation, and application of a force to the container greater than a threshold force.

Abstract: A pill dispenser includes a case body including a first compartment having a loading slot and a second compartment including a dispensing slot. The dispenser includes a cartridge configured to contain one or more pills and configured to align with the loading slot. The second compartment is adjacent to the first compartment. The dispenser further includes an actuator including a loading chamber. The actuator is joined to the case body proximate a first end of the case body and is rotatable about the case body from a loading position to a dispensing position. At the loading position, the loading chamber is aligned with the loading slot to receive a pill from the first compartment. At the dispensing position, the loading chamber is aligned with the dispensing slot to dispense the pill through the second compartment. A cap is removably coupled to a second end of the case body and is aligned with the second compartment and configured to receive the pill from the second compartment..

Abstract: A bottle teat (1) having a base portion (2), which has a connecting flange (3) and in which the bottle teat (1) is substantially circular in a cross section running perpendicularly to a longitudinal axis (9), having a lip-support portion (5) and having a nipple portion (6), which opens out in a teat tip (7), wherein, in a direction perpendicular to its longitudinal axis (9), the bottle teat (1) has, in the lip-support portion (5), a non-circular cross section with a longitudinal axis (10) and a transverse axis (11), which is shorter than the longitudinal axis (10), characterized in that the base portion (2) and the lip-support portion (5) have provided between them a flex portion (4), which has enhanced flexibility in relation to the base portion (2) and the lip-support portion (5), wherein the flex portion (4) has a circumferentially encircling depression (15) in the form of anindent (19) and/or of a smaller wall thickness than in the portions adjacent to the depression (15), and therefore, about an axis run

Abstract: A medical device position notification system including a negative pressure device. The medical device is configured to be inserted into an orifice of the patient. The negative pressure device provides information related to the position of the medical device in the patient's body and communicates the information in real-time. The negative pressure device may also be coupled to a sensor, processor, and display device and indicates the position of the medical device in the patient's body in real-time.

Abstract: A tubing assembly for use with electronic catheter guidance systems is provided and includes a catheter and an acoustic sensor. The catheter extends in a longitudinal direction and has a proximal end and a distal end that define a lumen therebetween. Further, the catheter is configured for placement within a patient's digestive tract. The acoustic sensor can be located within the lumen of the catheter or in a sampling chamber connected to the catheter. The acoustic sensor can communicate with a processor to deliver sound data to a display device. The appearance of random spikes on a frequency versus time spectrogram can indicate placement of the catheter in the digestive tract, while a rhythmic/repetitive pattern on a frequency versus time spectrogram can indicate placement of the catheter in the respiratory tract. A catheter guidance system and method for accurately placing a catheter in the digestive tract are also provided.

Abstract: Provided are methods and compositions relating to a dental composition more specifically to prepare the damaged dentin of the tooth prior to repair. The dental compositions include a bioactive glass and a non-aqueous solvent comprising an alcohol, anti-inflammatory and anti-pain reliver.

Abstract: An oil-gel-form external preparation for skin contains a compound represented by the following General Formula (1), an isomer thereof, and/or a pharmaceutically acceptable salt thereof. A partially cross-linked methyl polysiloxane; allows easy penetration of the compound from the preparation into the skin while enhancing the percutaneous absorbability and improving the intradermal retentivity. In the formula, R1 represents a C1-C4 linear or branched alkyl group substituted by a carboxyl group(s), or a C1-C4 linear or branched alkyl group substituted by a carboxylic acid ester group(s) having a C1-C4 alkyl chain, and R2 and R3 each independently represent a C1-C4 linear or branched alkyl group.

Abstract: Described herein, a water-soluble personal cleansing product, its uses, methods and kit, preferably a water-soluble facial cleansing product, comprising a water-soluble fibrous structure; wherein the water-soluble fibrous structure comprises a plurality of fibrous elements; wherein the plurality of fibrous elements comprises: one or more fibrous element-forming materials comprising one or more hydroxyl polymers comprising a natural starch and/or a modified starch; wherein the plurality of fibrous elements is substantially free of surfactant; wherein the water-soluble personal cleansing product comprises one or more surfaces wherein the one or more surfaces are coated with an oily composition, wherein the oily composition comprises one or more oil ingredients. Alternatively, the one or more surfaces are coated with a cleansing composition comprising one or more surfactants; and wherein the cleansing composition is substantially free of alkyl sulfate and alkyl ether sulfate type of surfactants.

Abstract: The present disclosure provides a pair of tooth-attachable patches for upper teeth and lower teeth, each of the patches including: a drug layer to be attached to teeth; and a backing layer laminated on the drug layer, wherein the heights of the patches for upper teeth and lower teeth are shorter than the crown lengths of maxillary and mandibular central incisors, respectively. The tooth-attachable patches of the present disclosure are prevented from being in contact with the incisal surface of teeth, thereby reducing foreign body sensation while the patches are attached to the teeth.

Abstract: Core-shell particles and methods of making and using thereof are described herein. The core is formed of or contains one or more hydrophobic materials or more hydrophobic materials. The shell is formed of or contains hyperbranched polyglycerol (HPG). The HPG coating can be modified to adjust the properties of the particles. Unmodified HPG coatings impart stealth properties to the particles which resist non-specific protein absorption and increase circulation in the blood. The hydroxyl groups on the HPG coating can be chemically modified to form functional groups that react with functional groups and adhere the particles to tissue, cells, or extracellular materials, such as proteins.

Abstract: Gel compositions including at least one copolymer of vinylpyrrolidone and acrylic acid, at least one film forming agent, and at least one coloring agent, and methods of applying such compositions to keratinous materials, are provided.

Abstract: Emulsion compositions including at least one polymer including imide group(s), at least one humectant, and at least one copolymer of vinylpyrrolidone and acrylic acid. and methods of applying such compositions to keratinous materials, are provided.

Abstract: A cosmetic ink composition comprises a particulate material, a polymeric dispersant, a rheology modifier, and a surface tension modifier, wherein the surface tension modifier is selected from the group consisting of C1-C16 alcohols, C5-C18 diols, and mixtures thereof. The particulate material can have a Particle Size Distribution D50 of about 100 nm to about 2,000 nm. The rheology modifier can be selected from the group consisting of alkali swellable emulsion polymers, hydrophobically modified alkali swellable emulsion polymers, and combinations thereof. The cosmetic ink composition can have a surface tension of from about 20 to about 45 mN/m.

Abstract: The present invention is directed to a method for improving the occlusiveness of a topical pharmaceutical or cosmetic formulation in use in a patient in need thereof, comprising adding to the formulation at least 0.1- to about 10% w/w of one or more of a monofatty acid ester of glycerin and/or one or more of a monofatty acid ester of glycol, or mixtures thereof. The present invention is also directed to a method for maintaining skin barrier efficiency of the stratum corneum of a patient in need thereof, comprising applying to the skin of said patient a pharmaceutical or cosmetic formulation containing at least 3% w/w of one or more of a monofatty acid ester of glycerin and/or one or more of a monofatty acid ester of glycol, or mixtures thereof.

Abstract: Disclosed is a process for preparing an encapsulated fragrance composition. The composition comprises a plurality of microcapsules dispersed in a dispersion medium. The microcapsules comprise a core and a shell around the core. The process comprises the consecutive steps of: a) Providing an aqueous phase (I) comprising at least one anionically modified polyisocyanate (A); b) Providing an organic phase (II) comprising at least one fragrance ingredient; c) Mixing the aqueous phase (I) and the an organic phase (II) to obtain a mixture; d) Forming an emulsion comprising droplets of the organic phase (II) in the continuous aqueous phase (I); e) Adding at least one polyfunctional amine; f) Effecting formation of shells around the droplets formed in step d), to obtain a dispersion of microcapsules. The process comprises the additional step of adding a polyisocyanate (B), which is different from polyisocyanate (A).

Abstract: Provided is a method of preparing a bioactive substance-encapsulated ethosome, the method including: preparing an aqueous solution of a bioactive substance, preparing a lipid-dissolved solution by dissolving lipids in ethanol, preparing a hydrated liquid crystalline phase by hydrating the lipid-dissolved solution by mixing and agitating the bioactive substance aqueous solution together with the lipid-dissolved solution, and preparing an ethosome solution by adding purified water to the hydrated liquid crystalline phase to produce a mixture and agitating the mixture.

Abstract: A method for injecting aqueous solutions as a bolus of cells below the dermis, into the hypodermis and the surrounding tissues for more profound cosmetic outcomes than a topical approach. The application of intravenous bolus subdermal solutions can not only nurture the skin but for cases where the skin is not nurtured or hydrated by this application the side effects of the aspects that cause local injury or irritation can also upregulate healthy skin cells and biological cells and tissues related to the skin to improve the health and appearance of the skin and its neighboring tissues and structures.

Abstract: A remineralization dentifrice utilizing submicron calcium particles is used to help trigger the oral environment's natural remineralization process. The submicron calcium particles act as a seed to initiate the process. Various sources and forms of calcium are utilized, with or without fluoride ions, to various effect. The dentifrice is delivered as a dry, inorganic powder to the user for maximum effect.

Abstract: A system, computer readable medium and method for selective brightening of hair, the method may include or may be preceded by applying at least one photosensitive material to the hair. The method may also include forming at least one pattern of brightened hair by illuminating the hair by at least one pattern of illumination.

Abstract: The present disclosure relates to a pump-type toothpaste composition capable of being provided as contained in a pumping type container, and to a pump-type toothpaste composition improving the spreading property to a tooth as the toothpaste composition discharged to a toothbrush penetrates into the toothbrush and having an effect of ultimately delivering a medicinal ingredient continuously for a long time in the oral cavity. In addition, the present disclosure relates to a pump-type toothpaste composition with excellent commercial value, which can ensure discharge stability without hardening and accordingly, can be used in a pump-type container equipped with a dispenser pump (dip pump), which has a remarkable problem of hardening in the discharge port due to free movement of external air because of properties of the container, and thus can ensure even the convenient use.

Abstract: Suggested is the use of [6]-paradol for stabilizing cosmetic compositions, wherein the cosmetic compositions are selected from the group consisting of cleansing compositions and fragrance compositions.

Abstract: This invention relates to an antimicrobial composition, especially one which provides synergistic anti-dandruff or anti-acne efficacy. This is achieved through a judicious combination of select essential oil actives chosen from thymol, or terpineol and certain antimicrobial lipids selected from sapienic acid, palmitoleic acid, sphingosine, dihydrosphingosine, phytosphingosine, and 6-hydroxysphingosine. These compositions can be delivered through very many different types of personal care products e.g. shampoo, conditioner; face wash or hand wash product; or a leave on cream/lotion.

Abstract: Disclosed is a regenerating composition having skin lifting and anti-age effect based on chlorinated derivatives of acetic acid, propylene glycol and sodium hydroxide, for use in the treatment of skin blemishes caused by stretch marks, acne scars, sun damage, skin sagging, hyperpigmentation, scars in various parts of the body, such as face, neck, chest, breast, inner thighs, arms, mons pubis, labia majora, inguinal and perianal areas, which is capable of overcoming the problems which are still present in the products of the prior art, a process of preparing the composition, and a method of use.

Abstract: The present invention belongs to the cosmetic field and relates to a cosmetic composition containing a specific combination of an ester, a polymer and water, which allows to increase the contact angle of a droplet of water present on a surface which was preconditioned with the cosmetic composition.

Abstract: The present invention belongs to the cosmetic field and relates to a cosmetic composition containing a specific combination of an ester, a polymer and water, which allows to reduce the white appearance when applied to wet skin.

Abstract: A composition for reducing conditions related to excess sebum on the skin and/or the scalp includes, for 100% of its weight: a) 60.0-75.0 wt. % of an organic solvent selected from 1,2-propanediol, 1,3-propanediol, 1,4-butanediol, 1,3-butanediol, 1,2-butanediol, 2-methyl-2,4-pentanediol, 1,6-hexanediol, 1,8-octanediol, or a mixture of the 10 compounds; b) 0.1-2.0 wt. % of a composition including a quantity by weight x, expressed as equivalent by weight, of 1-O-(2-caffeoyl)maloyl-3,5-O-dicaffeoyl quinic acid, which is higher than or equal to 200 mg/g of a compound of general formula (I): formula (I), in which Q1,-Q5 are, independently from each other, the hydroxyl radical or one of the salts thereof or a radical selected from the radicals caffeoyl, maloyl, caffeoyl maloyl and maloyl caffeoyl. At least one of Q1-Q5 is neither the radical —OH, nor one of the salts thereof; and c) between 20.0 wt. % and 35.0 wt. % of water.

Abstract: The present disclosure relates to hair treatment compositions comprising: (a) at least one reducing agent selected from thiol-based compounds, non-thiol-based compounds, and mixtures thereof; (b) at least one non-polymeric and non-thiol, mono-, di-, and/or tri-carboxylic acid, and/or a salt thereof; (c) at least one alkaline agent; and (d) optionally, at least one cationic surfactant; wherein the pH of the composition is from about 2 to less than 7. The disclosure also relates to methods for imparting hair care benefits to the hair such as straightening effects, volume reduction, frizz control, manageability, cosmeticity and smooth feel, in addition to conditioning benefits.

Abstract: A self-foaming cleansing compositions are provided. The self-foaming cleansing composition includes a) of one or more volatile silicone oil; b) one or more surfactants; and c) one or more polymers with suspending properties. The self-foaming cleaning composition is free of perfluoro compound.

Abstract: The present disclosure relates to systems, compositions, methods, and kits for coloring hair. The systems comprise at least two compositions: (i) a first composition comprising at least one pigment, and (ii) a second color changing composition comprising at least one color changing agent. The methods comprise changing the color of the hair by applying the first composition (i) onto the hair to change the hair from an initial hair color to a first hair color, and subsequently applying the second composition (ii) onto the hair to change the color of the hair from the first hair color to a second hair color.

Abstract: The present invention is applied to the skin care cosmetic field and relates to an antioxidant complex that exhibits excellent antioxidant capacity within cells. An antioxidant complex according to an embodiment of the present invention may comprise flavonoid having an antioxidant efficacy, and a solubilizer solubilizing the flavonoid.

Abstract: A cosmetic composition to prevent and/or ameliorate skin aging and applications thereof are provided in the present disclosure and the cosmetic composition comprises cyclic phosphatidic acid and citrus flavonoids which is hesperidin and/or hesperetin wherein the preventing and/or ameliorating skin aging include, without limitation, promoting moisture retention of stratum corneum, promoting skin elasticity, increasing presence or elasticity of collagens and elastins in fibroblasts, increasing transfers of fibroblasts, promoting anti-oxidation, increasing generation of hyaluronic acid, alleviating wrinkles and skin textures, moderating melanin, reducing skin oil and preventing transepidermal water losses.

Abstract: Methods of protecting skin of a mammal by application of silk-derived compositions useful for treating or preventing a wide variety of skin conditions. Silk solutions and silk mats are prepared and applied to the skin surface. The silk compositions may be self-adhesive or sutured to cover a wound or area of skin exposed to physical stresses and strains, thereby preventing a wound and/or promoting wound healing.

Abstract: The present invention relates to a dermal filler composition based on crosslinked hyaluronic acid, calcium phosphate material particles and carboxymethyl cellulose. The present invention further provides a process for preparing said dermal filler composition, and its use in cosmetic treatments such as for improvement of skin quality.

Abstract: The present invention provides an epilatory composition comprising an admixture of a hydrocarbon resin material and a mineral oil in weight ratio of 1.3:1 to 2.8:1, and, a polyethylene in the form of a homopolymer. An advantage of the compositions of the present invention is that they can be heated to the correct temperature of use, and/or to the correct viscosity, in an advantageous time.

Abstract: A self-foaming cleansing composition are provided. The self-foaming composition includes a) from about 0.5% to about 10% wt. % of one or more volatile silicone oils; b) from about 0.5% to about 25% wt. % of one or more surfactants stable at low pH; c) from about at least 1.2% of one or more polymers with suspending properties; d) from about 0.5% to about 5% wt% of one or more thickeners; e) from about 0.5% to about 15% wt. % of one organic acid as cosmetic active ingredient; the self-foaming cleansing composition having a pH in between about 3.4 and 5; the self-foaming cleansing composition starting to foam immediately after application of the compositions onto the skin; wherein the foaming cleansing composition is free of perfluoro compound; and wherein the weight percentages are based on the total weight of the self-foaming cleansing composition.

Abstract: Provided herein are methods, compositions, and kits for coating or coloring keratinous fibers, such as human hair. In accordance with an exemplary embodiment, a method of coating mammalian hair includes (a) providing an oil phase that includes at least one reactive condensation-curable film-forming amino-silicone pre-polymer, (b) after subjecting said oil phase to a pre-treatment duration to obtain a pre-treated oil phase, emulsifying the pre-treated oil phase with an aqueous phase that includes water, so as to obtain a pre-treated oil-in-water emulsion, (c) applying, on an external surface of individual hairs of the mammalian hair, the pretreated oil-in-water emulsion, (d) after partial condensation curing of said pre-polymer of the pre-treated oil-in-water emulsion has occurred so as to form an at least partially cured amino-silicone coat on the external surface of the individual hairs, optionally washing the hair.