Abstract: A non-invasive continuous blood sugar level monitoring apparatus integrated with real-time health support system. The blood sugar levels and other vital physiological information of the user can also be tracked wirelessly through the apparatus. The apparatus has an integrated real-time alert and reminder feature for notifying the user during medication and unusual physiological conditions. An automated diet and lifestyle recommendation solution is integrated into the device to help the user maintain healthy blood sugar and blood pressure levels. The low-powered telemetry device is used for communicating the stored physiological information of the user and the computed results between the network of devices.

Abstract: A human condition detection device comprises a depth image-taking module for taking a depth image of a target area. A millimeter-wave radar module detects breaths or heartbeats in the target area to provide a signal. A thermal image-taking module takes a thermal image of the target area. A processor module determines whether a person is in the target area based on the depth image. The processor module determines whether there is any breath or heartbeat based on the signal if a person is in the target area. The processor module determines whether there is any abnormal vital sign of the person in the target area based on the signal and the thermal image if there is a breath or heartbeat in the target area. The processor module actuates the warning module to provide a warning if there is an abnormal vital sign of the person in the target area.

Abstract: Provided is: a sensor module with a soft portion resistant to peeling off from the sensor head cover; and a blood pressure measurement device. A sensor module 63 includes a pressure sensor portion 71; a sensor head cover 73 including an opening 73a at a position opposite the pressure sensor portion 71; and a soft portion 74 that covers the pressure sensor portion 71 and is disposed in the opening 73a of the sensor head cover 73, a boundary portion between the soft portion 74 and the sensor head cover 73 including an outer edge portion 74b including an edge portion that is inclined or curved, when the sensor module is worn on a living body, with respect to a first direction along a circumferential direction of the living body or a second direction along a longitudinal direction of the living body.

Abstract: The invention relates to a new method, as well as diagnosis. A non-invasive marker, systems and equipment are also included.

Abstract: A bio-signal measurement apparatus comprises tool-less connectors, coupling targets, a controllable coupling selection arrangement, and a control arrangement. The tool-less connectors are for an electric contact with a separate docking apparatus or an electrode arrangement. The coupling targets include a battery and a data communication unit that performs electrically a plug-and-play data transfer with the separate docking apparatus. The tool-less connectors, the number of which is three, are electrically coupled with the controllable coupling selection arrangement, which electrically couples all the tool-less connectors with only one of the coupling targets at a time in response to control from the control arrangement.

Abstract: A neural interface arrangement comprising: a plurality of probes for subdural implantation into or onto a human brain, each probe including at least one sensing electrode, a coil for receiving power via inductive coupling, signal processing circuitry coupled to the sensing electrode(s), and a means for wirelessly transmitting data-carrying signals arising from the electrode(s); an array of coils is implanted for implantation above the dura, beneath the skull, the array of coils being for inductively coupling with the coil of each of the plurality of probes, for transmitting power to the probes; and a primary (e.g.

Abstract: Systems and methods for facilitating processing of cardiac information based on sensed electrical signals include a processing unit configured to receive a set of electrical signals; receive an indication of a measurement location corresponding to each electrical signal of the set of electrical signals; and generate, based on at least one of an annotation waveform corresponding to each electrical signal of the set of electrical signals and a set of annotation mapping values, an annotation histogram.

Abstract: A method includes receiving, via a plurality of electrodes in a heart, a collection of acquisitions, wherein each acquisition comprises a set of electrophysiological (EP) signals measured by the electrodes. A respective direction of arrival (DOA) and a respective distance relative to the electrodes from which the set of EP signals originated are estimated for at least some of the acquisitions. Based on the estimated DOA and distance, a timing error is estimated in at least an EP signal among the EP signals. A timing of the EP signal is adjusted to fit the estimated DOA and distance and correct the error. An EP map of at least a portion of the heart is generated using the set of EP signals, including the adjusted EP signal.

Abstract: A method includes receiving, via a plurality of electrodes in a heart, a collection of acquisitions, each including a set of electrophysiological (EP) signals measured by the electrodes. A respective direction of arrival (DOA) and a respective distance relative to the electrodes from which the set of EP signals originated are estimated for each acquisition. The acquisitions are aggregated, to form a statistical distribution of the acquisitions as a function of estimated DOA and distance. Using a statistical test, it is checked whether the statistical distribution is consistent, in accordance with a predefined consistency criterion. If the statistical distribution is found consistent, an estimated location in the heart of a focal source of an arrhythmogenic activity that generated the received EP signals is derived from the statistical distribution. The estimated location of the focal source is overlaid on an anatomical map of at least a portion of the heart.

Abstract: A method and system for high-throughput detection of coronary artery stenosis observes trends in abnormal or pathologic morphology of the electrocardiogram (ECG). A first set of ECG signals is monitored from a patient. A baseline measurement is generated from the monitored first set of ECG signals to contain nonpathologic ECG morphologies in each lead. A second set of ECG signals is monitored from the patient and a second mean measurement during or after stress is generated from the second set of ECG signals. A residuum signal is generated for each lead based on the baseline measurement and the second mean measurement. The residuum signals are averaged across the leads for each timepoint. T-wave heterogeneity is quantified based on the generated residuum signals and the averaged residuum signal at each timepoint, and used to detect coronary artery stenosis.

Abstract: A smart system for monitoring a cognition status of a user includes an electroencephalography (EEG) acquisition module, configured to capture a plurality of brainwave signals; an analog filter circuit, coupled to the EEG acquisition module and configured to amplify the plurality of brainwave signals; an analog to digital (ADC) circuit, coupled to the analog filter circuit and configured to transform the plurality of brainwave signals into a plurality of digital signals; and a digital signaling processing (DSP) circuit, configured to retrieve a plurality of characteristics from the plurality of digital signals to determine the cognition status of the user.

Abstract: The electronic device includes a pad module and a main module. At least part of the patch module is attached to a user to obtain a bio-signal of the user. The pad module includes a first housing and a plurality of first electrodes disposed in the first housing. The main module is configured to record the bio-signal of the user that is transferred through the pad module. The main module includes a second housing that is coupled with the first housing in a first direction. The main module also includes a plurality of second electrodes disposed in the second housing. The plurality of second electrodes are configured to make electrical contact with the plurality of first electrodes. The main module further includes a plurality of magnetic bodies disposed in the second housing to correspond to positions of the plurality of second electrodes.

Abstract: A device, having a housing; a power source configured to supply electrical power to a conductive percutaneous implant in a circuit including the conductive percutaneous implant and tissue of a patient adjacent to the conductive percutaneous implant; an electrical sensor configured to generate a signal indicative of at least one electrical parameter of the circuit; and at least one data processing system having one or more processors configured to receive the signal and analyze the signal to determine at least one of a presence or change of infection of the tissue, and pass a control signal to the power source to vary the electrical power responsive to determining at least one of the presence or change of infection of the tissue.

Abstract: A table for an MRI system includes a top surface for supporting a patient being imaged and a motion sensor for sensing motion of the patient. The motion sensor is located below the top surface and includes a self-resonant spiral (SRS) coil and a coupling loop. The coupling loop generates a drive RF signal to excite the SRS coil to radiate a magnetic field having a predefined resonant frequency. The coupling loop also receives a reflection RF signal from the SRS coil. The motion sensor is located such that at least a portion of a torso of the patient being imaged is within the magnetic field. A controller is configured to detect patient motion based on the reflection RF signal.

Abstract: The present disclosure relates to a multi-channel magnetic resonance imaging RF coil (114) with at least four channels and comprising a coil element for each of the channels, the RF coil (114) further comprising for each coil element a socket (300-306) that is electrically coupled to said coil element via a respective first transmission line (209), each socket (300-306) being adapted for receiving a plug for providing an RF signal via the respective first transmission line (209) to the respective coil element, wherein with respect to a predefined RF signal the differences in electrical length between any of the transmission lines is k?/4 where k is an integer and ? is the wavelength of the RF signal.

Abstract: Disclosed herein are an apparatus and method for imaging nano magnetic particles. The apparatus may include a measurement head in which a through hole for accommodating a sample including nano magnetic particles is formed and in which an excitation coil and a detection coil are installed, a field-free region generation unit for forming a field-free region, in which there are few or no magnetic fields, in a spacing area between the identical magnetic poles that face each other, and a control unit for applying a signal to the excitation coil when the measurement head is located inside the spacing area of the field-free region generation unit, controlling the field-free region so as to move in the sample, and imaging the 3D positional distribution of the nano magnetic particles included in the sample based on a detection signal output from the detection coil.

Abstract: Techniques are disclosed for positioning a patient couch in a patient receiving area of a magnetic resonance device for a magnetic resonance examination, which includes starting an introduction of the patient couch into the patient receiving area, acquiring monitoring data within an acquisition area of at least one sensor unit by means of the at least one sensor unit during the introduction of the patient couch into the patient receiving area, evaluating the monitoring data with respect to a selected area of an examination object and/or a selected area of the patient couch, and positioning the patient couch within the patient receiving area in dependence on an acquisition of the selected area of the examination object and/or the selected area of the patient couch in the monitoring data.

Abstract: Certain aspects relate to systems and techniques for medical instrument navigation and targeting. In one aspect, a system includes a medical instrument having an elongate body and at least one sensor, a display, a processor, and a memory storing a model of a mapped portion of a luminal network and a position of a target with respect to the model. The processor may be configured to: determine, based on data from the at least one sensor, a position and orientation of a distal end of the medical instrument with respect to the model, and cause, on at least a portion of the display, a rendering of the model, the position of the target, and the position and orientation of the distal end of the medical instrument.

Abstract: The disclosure relates to devices, systems and methods for detecting markers in breath, more specifically volatile and non-volatile markers associated with pulmonary diseases such as, for example, asthma, chronic obstructive pulmonary disease (COPD), or cystic fibrosis (CF), in exhaled breath condensate (EBC).

Abstract: Systems and methods for generating MRI images of the lungs and/or airways of a subject using a medical grade gas mixture comprises between about 20-79% inert perfluorinated gas and oxygen gas. The images are generated using acquired 19F magnetic resonance image (MRI) signal data associated with the perfluorinated gas and oxygen mixture.

Abstract: A dynamic vital-sign detection system includes a radio frequency (RF) detection device that generates a plurality of detection signals; a correction device that corrects the detection signals; a feature extraction device that processes the corrected detection signals according to at least one feature to obtain a plurality of extraction values and filters out unstable extraction values; and a vital-sign determination device that determines a vital sign according to the extraction values after filtration.

Abstract: Systems and methods for anatomical alignment are disclosed herein. In some embodiments, the systems and methods can provide accurate and continuous intraoperative validation of anatomical alignment, e.g., of the spine, hips, pelvis, and/or shoulders. An exemplary system can include a sensor and marker arrangement for measuring coronal imbalance. Another exemplary system can include a sensor and marker arrangement for shoulder or pelvic leveling. Yet another exemplary system can include a mechanical frame for establishing a simulated ground plane and projecting a plumb line from the simulated ground plane.

Abstract: A gait analysis and training system is provided, as well as methods of training, e.g., retraining gait in a patient. The system provides real-time external feedback to a patient is portable so that use is not limited to a clinic.

Abstract: Neurodegeneration can be assessed based on a gait signature, using a machine-learning model trained on gait metrics acquired for a patient, in conjunction with cognitive test data and neuropathology information about the patient. The gait signature can be derived from gait kinematic data, e.g., as obtained with a video-based, marker-less motion capture system.

Abstract: A step analysis device comprises at least one motion sensor for measuring instantaneous direction-specific movement of a user made during an ambulatory activity; at least one deviation indicator for alerting the user during the ambulatory activity upon determination of deviative motion; and a processor for processing signals generated by the at least one motion sensor that are indicative of the instantaneous direction-specific movement, and for comparing the instantaneous direction-specific movement with a normative direction-specific movement. The processor is operable to command the at least one deviation indicator to generate a predetermined biofeedback alert upon determining a deviation greater than a predetermined threshold level between the instantaneous direction-specific movement and the normative direction-specific movement.

Abstract: A system and a method for correcting posture are provided where the system comprises a smart bag including at least one pressure sensor and a first communication unit for transmitting an input value recognized by the pressure sensor to a user terminal. The user terminal including a second communication unit for receiving the input value from the first communication unit, an adhesion status checking unit for determining whether a user's human body and the smart bag are in close contact each other or not and determining an adhesion degree between the user's human body and the smart bag by using the input value received by the second communication unit, and a display unit for displaying the adhesion degree between the user's human body and the smart bag determined by the adhesion status checking unit.

Abstract: A medical device system and method that includes accelerometer circuitry configured to generate at least one signal, a memory, and processing circuitry coupled to the accelerometer circuitry and the memory. The processing circuitry is configured to monitor a patient for a Sit-To-Stand transition based upon the at least one signal, detect the Sit-to-Stand transition, determine if the patient has been inactive for a predetermined period of time prior to the Sit-to-Stand transition, and if the patient has been inactive for at least the predetermined period of time prior to the Sit-to-Stand transition, determine a body stability score of the patient.

Abstract: A fall risk evaluation method in a fall risk evaluation device that evaluates a fall risk based on a walking motion of a subject includes: acquiring walking data related to walking of the subject; detecting, from the walking data, at least one walking parameter of a vertical displacement of a waist of the subject in a stance phase of one leg of the subject, a vertical displacement of the waist of the subject in a swing phase of the one leg, an angle of a knee joint of the one leg in the stance phase, and an angle of an ankle joint of one foot in the swing phase; and determining a fall risk of the subject by using at least one walking parameter.

Abstract: A device for measuring the angular difference in a range of motion of the arms of a patient comprises a gripping bar, a housing, and an angle-determining assembly comprising a weighted needle and a compass. When the patient raises her arms to their unassisted physiological limits, the device indicates an angle that represents the angular difference in the range of motion between the arms of the patient.

Abstract: Aspects of automatically detecting periods of sleep of a user of a wearable electronic device are discussed herein. For example, in one aspect, an embodiment may obtain a set of features for periods of time from motion data obtained from a set of one or more motion sensors in the wearable electronic device or data derived therefrom. The wearable electronic device may then classify the periods of time into one of a plurality of statuses of the user based on the set of features determined for the periods of time, where the statuses are indicative of relative degree of movement of the user. The wearable electronic device may also derive blocks of time each covering one or more of the periods of time during which the user is in one of a plurality of states, wherein the states include an awake state and an asleep state.

Abstract: A method for automatically assessing information processing speed in a test subject is disclosed. In the inventive method, a first qualimetric activity parameter for sensorial transmission, cognition and motoric output activity is determined and a second qualimetric activity parameter for sensorial transmission and motoric output activity is determined. A third qualimetric activity parameter for cognition is determined by comparing the first and the second qualimetric activity parameters to each other, and the information processing speed in the test subject is assessed based on the first, second and third qualimetric activity parameters. The information processing speed can be determined by comparing the determined qualimetric activity parameters to a reference and the subject's cognitive impairment can then be determined from the processing speed. The inventive method can be computer implemented. A mobile device or system for carrying out the disclosed methods is also disclosed.

Abstract: An adaptive vital-sign detection method includes (a) receiving statuses in a first period, the status being stationary, motion or leave; (b) detecting whether the first period is interfered according to a status percentage in the first period; (c) receiving statuses in a second period if the first period is detected as being interfered, the second period being different from the first period; (d) determining an optimized status as being stationary if the first period is detected as being not interfered; (e) determining the optimized status as being motion or leave according to dynamic change of the statuses in the second period; (f) receiving vital signs in a third period when the optimized status is determined as being stationary or motion; and (g) processing the vital signs in the third period to obtain corresponding vital signs of the optimized status.

Abstract: A biological material measuring apparatus includes an infrared light source unit to radiate infrared light in entirety or part of a wavelength region including absorption wavelengths of a biological material, a prism to cause the infrared light radiated from the infrared light source unit to pass therethrough and emit the infrared light to a living body surface while being in contact with the living body surface, a light source to radiate light of a wavelength in a visible light region or a near infrared region to the prism, and a light position detector to detect a path of light from the light source by detecting light from the light source which is emitted from the prism.

Abstract: [Problem] To provide a device which reduces individual differences in lipid concentration measurements by noninvasive lipid measurements. [Solution] The invention comprises: an irradiation unit irradiating a light of a predetermined light intensity onto an organism; a light intensity detection unit positioned at a predetermined distance from the irradiation unit and detecting the light intensity emitted from the organism; and a control unit calculating, on the basis of the light intensity, the blood flow turbulence intensity, and calculating, from the turbulence intensity, the lipid concentration.

Abstract: A method and an apparatus for separating a composite signal into a plurality of signals is described. A signal processor receives a composite signal and separates a composite signal into separate output signals. Feedback from one or more of the output signals is provided to a configuration module that configures the signal processor to improve a quality of the output signals. In one embodiment, calibration data from multiple calibration data sets is used to configure the demodulation of the composite signal into separate output signals.

Abstract: A pulse oximeter may reduce power consumption in the absence of overriding conditions. Various sampling mechanisms may be used individually or in combination. Various parameters may be monitored to trigger or override a reduced power consumption state. In this manner, a pulse oximeter can lower power consumption without sacrificing performance during, for example, high noise conditions or oxygen desaturations.

Abstract: Disclosed herein are implantable devices coated with a reagent, and methods of preparing and utilizing such devices. The implantable device may comprise an implantable light conduit. The present disclosure enables a more precise registration between the reagent and the device implanted in the target tissue of a subject.

Abstract: A pretreatment method and an in-vivo component measuring device in which problems caused by bubbles is suppressed is provided. The pretreatment method uses an electrode sensor 21 for measuring a measurement target component contained in a measurement sample collected from a subject, and a liquid used for pretreatment of measurement, the pretreatment includes step (A) for forming a droplet 8 of liquid, step (B) for pressing the droplet 8 of liquid onto the surface of the electrode type sensor 21 by relative movement of the droplet 8 of liquid and the electrode type sensor 21, and step (C) for removing the droplet 8 pressed against the surface of the expression sensor 21.

Abstract: Method and apparatus for optimizing analyte sensor calibration including receiving a current blood glucose measurement, retrieving a time information for an upcoming scheduled calibration event for calibrating an analyte sensor, determining temporal proximity between the current blood glucose measurement and the retrieved time information for the upcoming calibration event, initiating a calibration routine to calibrate the analyte sensor when the determined temporal proximity is within a predetermined time period, and overriding the upcoming scheduled calibration event using the current blood glucose measurement are provided.

Abstract: Disclosed is a non-invasive system for testing blood sugar and a method of the same. The system includes a case, a control key unit, an input electrode unit, a signal filter unit, a signal transformation unit, a control processing unit, a signal amplification unit, an output electrode unit, a driver, a display unit, and a battery unit for preliminarily testing and instantly showing blood sugar or glucose in a non-invasive manner. Owing to a simple structure without any additional device or connection wire, the system is easy to use and practical to assist the user to readily test blood sugar. As a result, the present invention effectively avoids any potential risk of infection of bacteria or other microorganism due to frequently sampling the blood by pricking the finger, and particularly provides a function of fast and readily testing blood sugar everywhere for long term monitoring.

Abstract: Noninvasive glucose monitoring has been a long-standing need in diabetes management. Among many approaches to meeting this need, Raman spectroscopy has attracted attention due to its molecular specificity. Previous Raman-based glucose sensing can predict blood glucose concentration based on a statistical correlation between the reference glucose concentration and unspecified spectral features. However, the lack of glucose Raman peaks and non-prospective prediction have led to questions about the effectiveness of in vivo Raman spectroscopy for transcutaneous glucose sensing. Here, we disclose technology for directly observing distinct glucose Raman spectra from skin. The Raman signal intensities were proportional to the reference glucose concentrations in three live swine glucose clamping experiments. Tracking the spectral intensity based on the linearity enables prospective prediction with high accuracy in within-subject and inter-subject models.

Abstract: Disclosed herein are systems and processes for measuring, monitoring, processing, and visualizing biological data including blood glucose levels. In various embodiments, a biomarker monitoring fitness system may facilitate one or more of the monitoring of fitness data including blood glucose levels measured by continuous glucose monitoring (CGM) sensor for an individual user or group of users, the prediction of carbohydrate intake needs or insulin delivery needs during physical activity of a user and the active indication thereof to the user and/or a delivery system of the user, and the collection and management of de-identified and identifiable user fitness data including blood glucose data.

Abstract: One variation of the method for managing blood loss of a patient includes: receiving an image of a physical sample; extracting a feature from an area of the image corresponding to the physical sample; estimating a blood volume indicator of the physical sample according to the extracted feature; estimating a patient blood loss based on the blood volume indicator; estimating a euvolemic patient hematocrit based on an estimated patient blood volume and the estimated patient blood loss; receiving a measured patient hematocrit; and generating a volemic status indicator based on a comparison between the measured patient hematocrit and the estimated euvolemic patient hematocrit.

Abstract: A chip-scale integrated multi-wavelength biological sensing device employing a plurality of filter-sensor assemblies is provided. The plurality of filter-sensor assemblies can include sufficient number of optical channels enabled by plasmonic filters having different nanoscale patterns and provided directly on an array of photodetectors. Combined with simultaneous illumination of light including multiple peak wavelengths with small full width at half maximum values, the independent optical channels of the plurality of filter-sensor assemblies enable correlation of detected optical signals with biological parameters. Signal processing methods for robustly extracting The PPG signals can be extracted by a robust signal processing method. Successful measurement of peripheral blood oxygen (SpO2) and blood pressure has been demonstrated.

Abstract: Systems, methods and devices for reducing noise in health monitoring including monitoring systems, methods and/or devices receiving a health signal and/or having at least one sensor for health monitoring.

Abstract: Apparatus, methods, and systems for detecting alcohol concentrations of an individual, and in particular in vivo alcohol concentrations of an individual. Alcohol sensing compositions include at least one alcohol-responsive active area comprising a concerted enzyme system having at least a first enzyme and second enzyme capable of acting in concert to facilitate the detection of alcohol. At least one of the enzymes in the concerted enzyme system is a ketoreductase.

Abstract: Devices and methods for withdrawing bodily fluid from a patient are disclosed herein. In some embodiments, a handheld device can include a housing having an opening, and a skin-piercing assembly and a plunger positioned at least partially within the housing. The skin-piercing assembly can include a blade and a biasing member, such as a torsion spring. The plunger can be movable relative to the housing from a first position to a second position. In the first position, the plunger can engage the skin-piercing assembly to maintain the biasing member in a biased configuration. Movement of the plunger from the first position to the second position can disengage the plunger from the skin-piercing assembly to permit the first biasing member to drive the blade through and/or across the opening in the base.

Abstract: Systems and methods for detecting deceptive intent of a subject include observing eye movements of the subject and correlating the observed movements to known baseline neurophysiological indicators of deception. A detection system may record eye movement data from the subject, compare the eye movement data to a data model comprising threshold eye movement data samples, and from the comparison make a determination whether or not the subject is lying. The detection system may create an alert if deception is detected. The eye movements detected include saccadic and intersaccadic parameters such as intersaccadic drift velocity. Measurements may be collected in situ with a field testing device, such as a non-invasive, non-contact device attached to the subject's computing device and configured to non-obtrusively record the eye movement data.

Abstract: This invention relates to the field of treatment, prevention, and identification of persons at high risk of developing major depressive disorder based upon elevated concentration of serotonin 1A receptors (i.e., elevated serotonin 1A receptor binding potential). In particular, the current invention identifies offspring of parents with major depressive disorder who are at significantly elevated risk of developing major depressive disorder before any symptoms have occurred and treats these patients prior to any symptoms and more importantly before developing major depressive disorder. The invention also relates to the identification of persons who have discontinued treatment for major depressive disorder based upon elevated concentration of serotonin 1A receptors (i.e., elevated serotonin 1A receptor binding potential).

Abstract: Systems and methods for estimating emotional states, moods, affects of an individual and providing feedback to the individual or others are disclosed. Systems and methods that provide real time detection and monitoring of physical aspects of an individual and/or aspects of the individual's activity and means of estimating that person's emotional state or affect and change to those are also disclosed. Real time feedback to the individual about the person's emotional change, change or potential change is provided to the user, helping the user cope, adjust or appropriately act on their emotions.