Abstract: An electrical stimulation apparatus includes a generator of sequential electrical pulses having predetermined values of parameters that include pulse amplitude, and duration and frequency of the pulses, the generator having one or more separate stimulation channels that independently deliver the pulse sequences to body areas. An electrode for each channel transmits the stimulation pulses and is applied outside the patient's skin at a predetermined region and with a predetermined position relative to the position of another electrode associated to another channel. One or more electrodes are borne by a flexible support element, fastenable in a position related to body anatomy, and are distributed on an extension of the support element according to a predetermined design, together with the pulse generator connected to the one or more electrodes or with two or more pulse generators connected to different electrodes also supported by the support element.

Abstract: An apparatus and method of electrically coupling a previously implanted stimulation lead with a replacement neurostimulator device. The apparatus and method configured to operably couple a proximal portion of a neuromodulation adaptor including a plurality of electrical conductors spaced apart at a first pitch spacing to a corresponding plurality of electrical terminals of a replacement neurostimulator device, and operably couple a distal end of the neuromodulation adaptor including a plurality of conductor elements and an electrically active set screw spaced part of a second pitch spacing to a corresponding plurality of electrical connectors of a previously implanted stimulation lead.

Abstract: Neuromodulation electrodes and related methods to treat pelvic floor disorders, such as urinary and/or faecal incontinence, using electrical stimulation of the left and/or right branches of the dorsal genital nerves, or pudendal nerve, using a highly flexible electrode unit to obtain stable and comfortable contact with the cutaneous tissue or mucous membrane at or near the glans of the clitoris, in close proximity of the targeted nerve, for stabile neuromodulation applications.

Abstract: In some embodiments, systems and methods can include a wearable device with an electrically conductive skin interface that excites the underlying nerves from a transcutaneous surface stimulator. The device may be sized for a range of user sizes with stimulation electrodes positioned to target the appropriate nerves, such as the saphenous and/or tibial nerves. The stimulation could include burst stimulation, and involve receiving an input relating to autonomic nervous system activity of the patient, and modifying at least one brain or spinal cord autonomic feedback loop relating to bladder function based on the input to balance parasympathetic and sympathetic nervous system activity of the patient.

Abstract: A method of replacing a neurostimulator device. The method including explanting a previously implanted neurostimulator device from a site; operably coupling a replacement neurostimulator device to a previously implanted stimulation lead; and implanting a replacement neurostimulator device within the site, the replacement neurostimulator device having a volume of about ten cc's or less, and the previously implanted neurostimulator device having a volume of greater than about ten cc's.

Abstract: A system and method for ultra-focal transcranial magnetic stimulation are provided. In accordance with some aspects of the disclosure, the ?TM5 element includes a substrate and, supported by the substrate, microcoils formed using conductive micro-wires having a curved shape and capable of sustaining an electrical signal, wherein the microcoils are configured to produce a focality of stimulation of less than 10 mm when subjected to the electrical signal.

Abstract: The spinal cord stimulation device of this invention is configured for implantation into a patient so as to traverse the dura mater that surrounds the spinal cord. Placing the device in this location provides direct contact between the electrode and the cerebrospinal fluid (CSF), in close proximity to the spinal cord. The device has an intradural portion and an extradural portion that compresses and seals the dural membrane between them, securing the device in position and preventing leakage of CSF. The position of the device may be stabilized in relation to the spinal cord by way of a laminoplasty plate, bridging between the device and a vertebra. The device is electronically powered by an implanted pulse generator that produces a spectrum of signals to interrupt or otherwise attenuate transmission of pain mediating neural signals through the spinal cord.

Abstract: A stimulation device includes an adaptor component. The adaptor component couples a percutaneous lead to the stimulation device. The stimulation device may apply a stimulation signal to target tissue via the adaptor. A surgeon may place the stimulation device in a container and the adaptor component may be disposed outside of the container. Methods describe prolonged stimulation of target tissue via a stimulation device. The prolonged stimulation may be applied during and after a surgical procedure.

Abstract: A method is provided to deliver C tactile fiber stimulation to nervous tissue of a patient. The method comprises delivering a first tactile stimulation waveform to a first electrode combination within an array of electrodes located proximate to nervous tissue of interest. The method further provides sequentially delivering successive tactile stimulation waveforms to successive electrode combinations within the array of electrodes. The first and successive tactile stimulation waveforms include at least one series of pulses having a pulse amplitude and pulse frequency. Delaying delivery of the successive tactile stimulation waveforms by a firing delay, the pulse amplitude, pulse frequency and firing delay represent therapy parameters. The method manages at least one of the therapy parameters of the first and successive tactile stimulation waveforms to excite C tactile fibers of the nervous tissue of interest.

Abstract: An opto-electronic probe system is disclosed. The probe system has a probe element including at least one microelectrode, with the probe element being implantable in tissue of an anatomy to receive electrical signals generated within the anatomy. A subsystem is included for at least one of generating excitation signals to be used in stimulating the anatomy, or for receiving electrical signals received from the anatomy. An interface portion is included which is in communication with the subsystem for communicating at least one of electrical signals or optical signals indicative of the electrical signals received by the microelectrode.

Abstract: The present invention provides a wearable device, a system for manufacturing a wearable device and a method of neural activity control. The device for temporal interference simulation includes a pair of electrodes at penalizable location. The electrodes each send out a high frequency electromagnetic fields with a very slight difference in the two frequencies. The fields superimpose at a specified region of the brain, which is customized depending on the location of neural activity control, to create a low frequency refractory wave envelope. The low frequency wave inhibits or stimulates local neurons to control electrical activity within that region.

Abstract: A method for treating conditions associated with thalamocortical dysrhythmia. The method includes applying transcranial low voltage electrical stimulation (TLVES) therapy or transcranial magnetic stimulation (TMS) therapy to a patient in need thereof, and administering to the patient a dissociative anesthetic during the TLVES therapy or the TMS therapy. A number of conditions including tinnitus, depression and pain can be treated with TLVES or TMS in combination with the dissociative anesthetic, such as an NMADR inhibitor, including ketamine.

Abstract: Methods and devices including amorphous magnetic microwires are provided for biomedical energy transfer for diagnosis or therapy, to promote cellular growth, or to deliver pharmaceutical agents. Applications of the technology include in sensors, actuators, and therapeutic coatings, and for increasing the amount, directionality, or length of nerve growth. The technology also can be utilized for nerve regeneration, hyperthermic treatment of tumors, vascular theranostics, probing a nerve, stimulating a nerve, sensing a biological condition, catheterization, and micro-actuation.

Abstract: A wearable device for mammary glands in human beings, comprises a first brassiere cup and a second brassiere cup, the first brassiere cup including a first inner surface and the second brassiere cup including a second inner surface, a first layer of a diaphanous material attached to the first inner surface and a second layer of the diaphanous material attached to the second inner surface, a plurality of first openings provided in the first layer and a plurality of second opening provided in the second layer, a plurality of first Light Emitting Diodes (LEDs) provided between the first inner surface and the first layer, a plurality of second LEDs provided between the second inner surface and the second layer, a sensor unit adapted to determine one or more physiological parameters and an underwire connecting the first and the second brassiere cups.

Abstract: A therapeutic device, for human hair and skincare, comprises a gripping unit a functional unit including a first functional module and a second functional module, the first functional module including a first plate and a second functional module including a second plate, wherein a second surface of the second plate is oriented in an opposite direction to a first surface of the first plate, a plurality of teeth oriented in the direction of the orientation of the first surface, the plurality of teeth including a plurality of respective primary Light Emitting Diodes (LEDs), a plurality of secondary LEDs provided on the second plate and oriented in the direction of the orientation of the second surface and a sensor unit configured to determine hair distribution data on a body portion of a user.

Abstract: A laser ionization therapy assembly having a reservoir defined by a peripheral wall and a base; a support device having a support coupling member and a support opening; and a laser module accommodating a laser diode, the laser module having an opening and a laser module coupling member, wherein the support device is fixedly attached to the peripheral wall of the reservoir and the laser module is detachably coupled thereto, wherein the laser diode is positioned at an angle relative to the base of the reservoir so that laser light is directed through the openings of the laser module and support device to a predetermined location within the reservoir at a height of between ½ inch to 1 inch above the base, and wherein the laser light has a wavelength of between about 630 and 640 nm and a peak power of about 10 mW.

Abstract: Devices and approaches for activating cross-linking within corneal tissue to stabilize and strengthen the corneal tissue following an eye therapy treatment. A feedback system is provided to acquire measurements and pass feedback information to a controller. The feedback system may include an interferometer system, a corneal polarimetry system, or other configurations for monitoring cross-linking activity within the cornea. The controller is adapted to analyze the feedback information and adjust treatment to the eye based on the information. Aspects of the feedback system may also be used to monitor and diagnose features of the eye. Methods of activating cross-linking according to information provided by a feedback system in order to improve accuracy and safety of a cross-linking therapy are also provided.

Abstract: A method of radiotherapy treatment planning comprises optimizing a treatment plan based on at least one proposed dose map according to a set of clinical goals The resulting dose distribution is compared to the at least one clinical goal, and if the optimized dose distribution does not fulfil the at least one clinical goal, continuing with step d the dose map is adjusted before a new treatment plan is optimized. When the optimized dose distribution fulfils the clinical goals, the treatment plan is accepted.

Abstract: Computed tomography (CT) measurement data of the patient is acquired using a CT device having a quantum counting X-ray detector, and the CT measurement data is processed to generate result data, considering a specific information content of the CT measurement data resulting from the use of the quantum counting X-ray detector in acquiring the CT measurement data. The result data is suitable for use in the planning of irradiation of the patient. The result data is provisioned to an interface such that the result data is usable for planning the irradiation of the patient.

Abstract: Information that describes a target inside a patient to be treated with radiation is accessed from computer system memory. An arrangement of spots inside the target is determined. Each the spots corresponds to a location inside the target where a respective beam of radiation is to be directed during radiation treatment of the patient. A dose rate for each of the beams is determined. The dose rate for each beam is a dose delivered in less than one second to a spot corresponding to that beam. For example, each beam can deliver at least four grays (GY) in less than one second, and may deliver as much as 20 Gy to 50 Gy or 100 Gy or more in less than one second. A radiation treatment plan, that includes the arrangement of the spots and the dose rate for each of the beams, is stored in computer system memory.

Abstract: Provided is a headset dosimeter for using a coulomb-stimulation device for breaking up iron-oxide mineralization with protein aggregation using a traversing ion beam comprising a head mounting part, a first stereoscopic block provided on one side to the head mounting part, and a second stereoscopic block provided at an opposite position to the first stereoscopic block based on the head mounting part, wherein each of the first stereoscopic block and the second stereoscopic block may include a mounting part capable of receiving at least one radiographic film.

Abstract: A water tank apparatus for use with a radiotherapy system, comprising a base, side walls, end walls, and a top wall, together defining a tank structure, wherein an aperture is defined in the top wall near one end wall, and an upstanding rim surrounding the aperture; and a sensor mounting body fixed within the tank structure, and having formations by which a radiation sensor can be located in a fixed position within the tank structure so as to detect radiation at a point equidistant from the side wall and top wall and base.

Abstract: A quality control device which enables all the routine quality controls of linear particle accelerators (LINACs), which are used in radiation oncology, to be performed automatically. The quality control device includes a sensor panel having at least twenty one first optical sensors, at least two laser distance sensors, at least two g-sensors, at least one second optical sensor disposed at a depth of 1 mm from a surface of the sensor panel, and a 2 mm diameter hole located on the surface of the sensor panel above the at least one second sensor; a measurement panel including at least one linear light detector and at least one linear radiation detector for determining an isocenter that receives light and a possible cross-wire angle by performing a light area scanning; an inclinometer providing an angle correction by obtaining angle information from each position of the measurement panel; and a motorized system.

Abstract: A method for creating an irradiation plan. The method may include receiving an irradiation therapy plan for irradiating a target with a proton beam from a gantry. The irradiation therapy plan may have a plurality of irradiation spots for delivering protons to the target. The method may include identifying a rotational profile for angular rotation of the gantry with respect to the target, a slew time for a proton beam to travel between each of the plurality of irradiation spots, and an amount of protons to be delivered to each irradiation spot. The method may also include creating an irradiation plan. The irradiation plan may include a plurality of groups of irradiation spots based on the rotational profile, the slew time, and the amount of protons to be delivered to each irradiation spot. Each group of irradiation spots may be associated with a respective portion of the angular rotation.

Abstract: Endure is a nutritional supplement designed to slow the negative effects of radiation on the brain, eyes and intestines while an individual is traveling in the upper atmosphere or outer space. It combines 6 natural compounds shown in clinical trials to reduce radiation-induced inflammation, into a single supplement.

Abstract: The present invention relates to a skin cleansing composition which can sufficiently exhibit an excellent keratotic plug-removing effect without a burden, such as pain and irritation, on the skin. The skin cleansing composition comprises the following components (X) and (Y): (X): one or more selected from the group consisting of 2-amino-2-hydroxymethyl-1,3-propanediol, 2-amino-2-methyl-1-propanol, and 2-amino-2-methyl-1,3-propanediol; and (Y): a basic material other than component (X), and has a pH of 8.3 or more and 12.5 or less at 25° C.

Abstract: Impact tools are described herein. An example of an impact tool includes a first elongate member and an impact member. The impact member is attached to the first elongate member and has a first end, a second end, a length that extends from the first end to the second end, a first side, a second side, and a plurality of projections disposed on the second side. Each projection of the plurality of projections has a first end attached to the impact member and a second end. The plurality of projections are configured on the impact member such that at least two projections of the plurality of projections intersect a first hypothetical plane disposed between the impact member second end and the second end of each projection of the plurality of projections.

Abstract: A securing device configured for moving along with a person to be secured is disclosed. A housing has a groove and two opposed sidewalls which are spaced apart such that the groove and the sidewalls partially enclose a securing means. A lever with an attachment region is provided, to which the person is attachable, wherein the lever is pivotally mounted between the sidewalls. The lever is adapted and pivotable such that, in a securing position in which the securing means is blocked within the groove against a displacement in at least one direction along the securing means, the securing means is pressable into the groove and the attachment region protrudes out of the housing for being operated, and a release position in which the securing means is displaceable within the groove, the lever is covered between the sidewalls in the housing, such that attaching the person to the attachment region is prevented.

Abstract: A support harness with shock reducing elements includes a saddle with a first lateral edge and a second lateral edge. A pair of bridge connectors is attached to and extends outwardly from the saddle. The first and second lateral edges each has one of the bridge connectors positioned adjacent thereto. The bridge connectors each include a first strap section secured to the saddle adjacent to an upper edge thereof, a second strap section secured to the saddle adjacent to a lower edge thereof, and a central strap section extending between the first and second strap sections. The first strap section includes a plurality folds therein. A break-away fastener extends through the folds and breaks to release the plurality of folds when a predetermined amount of force is placed on the first strap.

Abstract: Disclosed is a fire suppressant system for a cargo container, the system having: a pressure vessel disposed within the cargo container, an exterior surface of the pressure vessel defining a fire suppressant-opening; a seal member that covers the fire suppressant-opening; and a connection feature connects the seal member to the pressure vessel, wherein the connection feature that releases the seal member when exposed to a predetermined minimum temperature.

Abstract: A system and method fare disclosed for inerting a protected space. Process water is delivered to an anode of an electrochemical cell where a portion of the process water is electrolyzed to form protons and oxygen. The protons are transferred across the separator to the cathode, and process water is directed through a process water fluid flow path including a first side of a membrane. Gas is transferred to a second side of the membrane to form a de-gassed process water on the first side of the membrane, and the de-gassed process water is recycled to the anode. Air is delivered to the cathode and oxygen is reduced at the cathode to generate oxygen-depleted air. The oxygen-depleted air is directed from the cathode of the electrochemical cell along an inerting gas flow path to the protected space.

Abstract: An electrical device having a housing containing at least one electrical component and an automatic fire prevention or extinguishing system with at least one heat and/or smoke sensor, the at least one heat and/or smoke sensor is operably connected to a container holding a fire-retarding, fire-extinguishing or fire-prevention material and the container is arranged to dispense the fire-retarding, fire-extinguishing or fire-prevention material into the housing and/or onto the electrical component when the at least one heat and/or smoke sensor detects heat and/or smoke inside the housing, as the fire-retarding, fire-extinguishing or fire-prevention material is dispensed through at least one conduit operably connected to the container holding the fire-retarding, fire-extinguishing or fire-prevention material. Each conduit is arranged to track electrical wiring of the electrical device or track at least part of an outer surface of at least one electrical component of the device.

Abstract: A fire extinguisher includes a body defining a storage chamber containing an extinguishing agent, a gas generator configured to pressurize the extinguishing agent in order to dispense it outside the body through an exit opening. The exit opening is equipped with a misting nozzle, and the extinguishing agent has a solidification temperature less than ?10° C., the saturating vapor concentration of the extinguishing agent taken at ?10° C. and at 1 bar being less than the extinguishing concentration of the extinguishing agent determined according to the ISO 14520 standard for a heptane fire at 1 bar.

Abstract: A modular storage tank assembly including a body defining an internal volume structured to hold a fire suppression agent. The body including multiple planar side portions defining the internal volume, at least one body inlet aperture, and at least one body outlet aperture. The modular storage tank assembly also including a case. The case including a case body, a first flange on a first side of the case body and a second flange on a second side of the case body, at least one case inlet aperture, and at least one case outlet aperture.

Abstract: A fire protection sprinkler assembly having a frame that includes a pair of frame arms configured with a geometry that strengthens the frame arms to resist impact, shear and/or torsional loads. The sprinkler assembly can be configured for installation in any one of an upright sprinkler, a pendent sprinkler, horizontal sidewall sprinkler or a recessed sprinkler.

Abstract: A fire detection device and method therefor are able to provide automatic activation so as to extinguish a fire. The fire detection can be rapid and temperature-based. In one embodiment, a heat collector can be provided to enhance thermal responsiveness. Activation of the fire detection device can be electrically induced to release an extinguishing agent at the fire. The activation can be protected such that it is durable and unaffected by vibrations.

Abstract: The present invention relates to aqueous compositions for suppressing fires, comprising surfactants and/or hydrotropes, particulate inorganic materials selected from the group consisting of perlite, talc, calcium carbonate, kaolin, dolomite, mica, and bentonite, and combinations thereof, and optionally one or more additives. The invention further relates to uses of such particulate inorganic materials, as well as dry precursor compositions, fire suppressing compositions, and methods of making them.

Abstract: There is provided a trampoline scooter (10) includes an elongate deck (12) including an upper surface (12a), a convex lower surface (12b), and rounded lateral edges (16) provided between the upper and lower surfaces (12a, 12b) for engaging a trampoline, a head tube (20) connected to the deck (12), and a column (22) disposed through the head tube (20), an upper end of the column (22) extending beyond the head tube (20) for receiving a set of handle bars.

Abstract: An exercise machine has a supporting frame; a resistance fan on the supporting frame, the resistance fan being configured to provide an amount of resistance to a user of the exercise machine; a housing enclosing the resistance fan, the housing having a plurality of openings through which air from the resistance fan is directed towards the user of the exercise machine; and a shroud on the housing. The shroud is movable with respect to the plurality of openings so as to redirect the air from the resistance fan without changing the amount of resistance provided to the user of the exercise machine.

Abstract: A portable lower limb therapy device having a support base and a force transfer system. The support base includes an exterior surface suitable to slide on smooth surfaces and an interior surface suitable to receive and conform to a foot of a user. The force transfer system embodied through one or two cords integrated with the support base and operates to transfer force applied behind and above the foot of a user that is in the support base to the support base. The portable lower limb therapy device may be used with a wearable anchor that is attachable to the thigh of the user of allows for the cord or cords to be fixed in place for the performance of static progressive stretch therapy motions without requiring ongoing manual force.

Abstract: A stretching device comprising an elongated band having a first end and a second end, a first handle coupled to the band proximate the first end, a second handle coupled to the band proximate the second end, and a boot coupled to the band between the first end and the second end, the boot adapted to engage with a body part of a person, horse, or other animal.

Abstract: An exercise device is provided to couple a user's limb to a resistance mechanism and to tighten on the user's limb by a force applied in opposition to the resistance mechanism. The device may include a strap including a first portion, a second portion, and a third portion. The strap may define an adjustable opening configured to receive the user's limb. The first portion and the third portion of the strap may be attached to a closed loop shape configured for coupling to the resistance mechanism. A fixed opening may be coupled to the strap, and the adjustable opening of the strap may be formed by passing the second portion of the strap through the fixed opening. The device may also include a flexible material coupled to the strap and defining a tube providing the fixed opening.

Abstract: An exercise device is provided with a first element disposed at a first side and a second element disposed at a second side. The first element includes gripping features to prevent skidding or sliding of exercise device when first element is abutting a surface. The second element includes sliding features to facilitate sliding of exercise device when second element is abutting the surface. Thus, when an exercise practitioner desires to use the exercise device to prevent movement of a particular body part against the surface, the practitioner places the first element against the surface. Conversely, when the exercise practitioner desires to use the exercise device to facilitate movement of a particular body part against the surface, the practitioner places the second element against the surface. The exercise device further includes an insert which may be removed and heated or cooled to provide heating or cooling pad/pack to a body part.

Abstract: A Rowing Machine, which includes a Main Bracket and a Cushion. The Main Bracket is equipped with a Slide Rail, the Cushion is slidably installed on the Slide Rail, and the Slide Rail is gradually bent upwards from front to back. Thereby, when the user uses the Rowing Machine, the Cushion can rise higher along the bent Slide Rail, which can more effectively enhance the user's exercise effect.

Abstract: An exercise machine monitoring and instruction system for the movement of an element of an exercise machine by an exerciser and providing automated feedback to the exerciser to help improve the exercise in real-time. The exercise machine monitoring and instruction system generally includes an exercise machine having a movable element that moves between a first position and a second position in a reciprocating manner, a sensor that detects a real-time position of the movable element, a processor in communication with the sensor to receive the real-time position data from the sensor related to a position of the movable element and a feedback device in communication with the processor that provides real-time instructions to the exerciser on how to adjust their workout to achieve a desired result.

Abstract: The present invention relates to a gymnastic machine (1) comprising a frame (2) having a base (21), wherein said base comprises a first (211) and a second (212) longitudinal member, a closed-circuit sliding-belt (3) associated with said base (21), arranged between said first (211) and said second (212) longitudinal member, on which a user can execute a gymnastic exercise, and a transmission assembly (5) having an electric motor (51), configured to move said sliding-belt (6), wherein said gymnastic machine (1) is characterized in that said electric motor (51) is arranged below said sliding-belt (6). The present invention also relates to a manufacturing method of a gymnastic machine (1).

Abstract: The present invention is a modular exercise system made up of two handles, a segmented track, and two or more sliding carriages. The invention allows a user to safely and incrementally practice front and side split exercises by providing specific and adjustable stability and support. The invention can be extended to accommodate taller users and can also be fully disassembled and packed into a compact travelling configuration.

Abstract: A system for physical rehabilitation comprises a clinician interface including a patient profile display presenting data regarding performance of a regimen for a body part. A patient interface presents instructions and status information regarding the performance of the regimen. The patient interface further presents a questionnaire soliciting responses to questions pertaining to current and past physical conditions of the patient. Selected responses to the questions cause the system to take actions, including preventing operation of a treatment apparatus by the patient, and/or transmitting an alert message to a clinician. The alert message may be transmitted within the clinician interface and/or as a real-time message outside of the clinician interface. A questionnaire is presented to the patient in response to occurrence of a triggering event pertaining to the patient's use of the treatment apparatus.

Abstract: A handle for a rowing machine is provided. The handle has a cursor control device which accepts user input. A processor is in electronic communication with the cursor control device and an electronic display. An electronic storage device comprises executable software instructions, which when executed, configure the processor to receive user input from the cursor control device and move the cursor on a graphical user interface (“GUI”) in response to the received user input or update the GUI based on user input.

Abstract: In a multi-piece solid golf ball having a core, an envelope layer, an intermediate layer and a cover, the core, an intermediate layer-encased sphere and the ball have surface hardnesses which satisfy a specific relationship, and the envelope layer, the intermediate layer and the cover have thicknesses which satisfy a specific relationship. Also, the core has a hardness profile in which the hardnesses at the core surface, core center, a position 5 mm from the core center, and a position midway between the surface and center of the core satisfy specific relationships. This golf ball, when used by mid- and high-level amateurs, enables the golfer to maintain an adequate distance on shots with a driver and achieve a good distance on iron shots, has a good spin performance on approach shots and has a good feel on impact. In addition, the ball has an excellent scuff resistance when struck with a grooved wedge.