Patents Issued in April 15, 2021
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Publication number: 20210106475Abstract: The disposable cleaning auxiliary tool comprises a flexible sheet-like non-liquid-permeable material being made to have a bottom portion, a duct portion arranged so as to extend further therebeyond from a location serving as soiled water outlet provided at an outer periphery of said bottom portion, a pouch-like water-receiving portion arranged at a surface at one side or surfaces at both sides of an extended tip of said duct portion, a cylindrical gas filled portion arranged at an outer peripheral portion other than the location serving as soiled water outlet at said bottom portion, and a gas filling inlet for filling said cylindrical gas filled portion, and is capable of being folded and stored when the cylindrical gas filled portion is not filled with gas, a concavity formed when the body of the bedridden individual pushes downward serves as a reservoir, another concavity formed serves as a drainage path.Type: ApplicationFiled: November 19, 2018Publication date: April 15, 2021Applicant: WANOCARE CO., LTD.Inventors: Yukie Nagai, Akie Kawabata
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Publication number: 20210106476Abstract: Patient support apparatuses, such as beds, cots, stretchers, recliners, operating tables, and the like include wireless mesh network transceivers that enable them to communicate with each other, and other devices, via mesh networks and/or ad hoc networks. One or more additional wireless transceivers are included, such as WiFi transceivers that enable direct communication with a healthcare facility network, such as an Ethernet. The mesh network communication between patient support apparatuses and other devices is used for any one or more of: extending the communication range of the existing IT infrastructure, efficiently routing data to the healthcare facility network, determining location of the patient support apparatuses and devices, transporting patient data from one patient support to the next as the patient moves, and for other aspects.Type: ApplicationFiled: December 23, 2020Publication date: April 15, 2021Inventors: Michael Joseph Hayes, Aaron Douglas Furman, Christopher John Hopper, John P. Geer, Joshua Elmer Mix, David Terrance Becker, Jonathan Mark Greenbank
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Publication number: 20210106477Abstract: Systems are disclosed that include: a mattress on a horizontal support, a vertical support for supporting the mattress, a container, and an element for guiding the container with respect to the mattress.Type: ApplicationFiled: October 28, 2020Publication date: April 15, 2021Inventor: Bernadette de ISAZA
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Publication number: 20210106478Abstract: A patient support apparatus and a method of notifying persons within a vicinity of the patient support apparatus are disclosed. The patient support apparatus includes a patient support structure for supporting a patient, an actuator for moving the patient, a notification system, and a controller coupled to the notification system and the actuator. The controller receives a selection of a remote control function via a communication network, generates a notification in response to receiving the selection of the remote control function, and transmits an output signal to the actuator based on the selection of the remote control function. The notification system executes the notification prior to the controller transmitting the output signal to the actuator.Type: ApplicationFiled: December 17, 2020Publication date: April 15, 2021Applicant: Stryker CorporationInventors: Anuj Sidhu, Alexander Bodurka, Akash Agrawal, Brajesh Kumar, Sachin Pachauri, Chandra Bhanu Vats
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Publication number: 20210106479Abstract: A person support apparatus includes a support surface having a patient facing surface and includes a head section, a seat section, and a foot section, the head section and the foot section being rotatable with respect to the seat section. One or more actuators are provided to rotate the head section and the foot section with respect to the seat section. At least one strain gauge is provided proximate the patient facing surface of the support surface to detect a change in pressure against at least one of the head section and the foot section. A controller is configured to transmit a signal to one or more of the actuators to rotate a corresponding one of the head section or the foot section in response to receiving data from the at least one strain gauge indicating a change in pressure that exceeds a predetermined reduction in pressure.Type: ApplicationFiled: October 2, 2020Publication date: April 15, 2021Applicant: HILL-ROM SERVICES, INC.Inventors: Robert Mark Zerhusen, Neal Wiggermann
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Publication number: 20210106480Abstract: The present invention provides an apparatus for moving a patient on a pad and holding the pad in place on a an anterior hip table or a standard surgical table. The pad works in conjunction with the reusable patient lifting/moving base, allowing nurses to more readily and easily move patients on the table in order to facilitate surgical positioning. The pad may also be used in combination with a post overlay to prevent injuries to the genital area of the patient.Type: ApplicationFiled: October 29, 2020Publication date: April 15, 2021Inventors: David J. Gomez, Nathan Winder
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Publication number: 20210106481Abstract: An apparatus and method for storing medical products such as pharmaceutical and medical products in climate controlled storage devices includes climate control systems in communication with inventory access and tracking systems.Type: ApplicationFiled: November 3, 2020Publication date: April 15, 2021Inventors: Thomas J. LARKNER, David A. FERRER, Jesse M. SMITH, Dennis H. SMITH, Adam A. CLOUD, Mark D. LOCKWOOD, Mark G. LOEFFELHOLZ, James R. EDWARDS
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Publication number: 20210106482Abstract: The invention relates to an infant positioning device for stabilizing and maintaining an infant in a fixed position for a lumbar puncture procedure. The device consists of a frame with openings for the infant's face and abdomen to support the infant in the proper position for the procedure and allow for unimpeded ventilation, a component of the frame to secure and stabilize the infant within the frame to prevent movement during the procedure, and an attachment stand to the frame that allows the frame to be free-standing.Type: ApplicationFiled: October 14, 2020Publication date: April 15, 2021Applicant: SafeTap LLCInventors: Brian Alverson, Ravi Stephen D'Cruz, Daniel Joseph Nelsen
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Publication number: 20210106483Abstract: A handset for controlling a device having a plurality of movable elements, the handset having a housing, a display on a front face of the housing, the display being divided into a plurality of zones, each zone including at least one icon switch, each icon switch being aligned with a respective associated icon, wherein each icon identifies a respective element or group of elements of a device to be controlled by the respective icon switch, and a plurality of physical switches on the front face, each physical switch being associated with a respective zone, and wherein each physical switch is configured to control movement of the element or elements shown by the icon or icons in the respective zone, and a control mechanism within the housing which is connected to the plurality of icon switches and the plurality of physical switches, the control mechanism being arranged to generate an output control signal for transmission to the device in response to an input command at the plurality of icon switches and the pluType: ApplicationFiled: April 3, 2019Publication date: April 15, 2021Inventor: Colin Moore
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Publication number: 20210106484Abstract: The present disclosure relates to an operating table, the operating table comprising a table top, a table top support and a column with a column head, wherein the sealing device is bellows assembled below the column head, or an adhesive in a hole and/or window on the holder of the cable, or a sealing gasket between the receiver and the column head, or a shield sealingly attached to the column head below the gear. The present disclosure further relates to control equipment, a lifting device, an intelligent charger, a column guide system for an operating table, as well as an operating table including the same.Type: ApplicationFiled: December 23, 2020Publication date: April 15, 2021Inventors: Kwang-un Clarence KING, Qiang HAO, Hao SHI, Jian WANG, Debao MA, Wei MA, Jipeng WANG, Jian YANG, Boon Khai ANG, Min Htun AYE, Arnd KUCHENBECKER, Falk GEORGI
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Publication number: 20210106485Abstract: The funeral tray can have an elongated bottom and an upwardly projecting wall peripheral to the bottom and leading to a raised rim, defining a concave shape sized and configured to receive the body of a deceased person, the upwardly projecting wall and the bottom being integral to one another and made of bio-based material.Type: ApplicationFiled: December 16, 2019Publication date: April 15, 2021Inventor: Jean-François HOUDE
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Publication number: 20210106486Abstract: A stretcher arrangement (2) comprising a first sheet (4) and a second sheet (6) to be arranged on a bed (8) having a first end (10) and a second end (12), and a length L along a longitudinal axis A. The first sheet (4) comprises a first surface (14), being a part of the first sheet that faces upward when the sheet is arranged on the bed (8). The second sheet (6) comprises a second surface (16), being a part of the second sheet (6) that faces upward when the sheet is arranged on the bed (8). The first surface (14) and the second surface (16) cover different parts of the bed surface, and border each other along a border line B that at least partly is essentially perpendicular to said axis A.Type: ApplicationFiled: October 15, 2020Publication date: April 15, 2021Inventor: Leif J.I. Lundblad
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Publication number: 20210106487Abstract: Rehabilitating an impaired body part of a subject such as a stroke patient includes systems, devices, and methods using an orthosis system configured to attach to the impaired body part and to move or assist in movement of the impaired body part. A control system is configured to operate the orthosis system in a mode in which the orthosis system first allows the subject to move volitionally or attempt to move volitionally the impaired body part in a predefined motion and then operates to move or assist in the predefined motion of the impaired body part. Additional modes of operation include a brain computer interface mode of operation and a mode in which the orthosis system operates in a continuous passive mode of operation comprising a plurality of repetitions of an exercise to move the impaired body part.Type: ApplicationFiled: October 12, 2020Publication date: April 15, 2021Inventors: Kern Bhugra, August Anderson
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Publication number: 20210106488Abstract: An orthosis device for a subject includes a main housing assembly configured to be worn on an upper extremity of the subject, and a body part interface assembly configured to be secured to the portion of the upper extremity and induce, as actuated by a motor mechanism, flexion and extension motion of the secured body part. A flexible intermediate member is interposed between the main housing assembly and the body part interface assembly, and is configured to flex or extend responsive to actuation by the motor mechanism to cause the body part interface assembly to flex or extend the secured body part.Type: ApplicationFiled: October 13, 2020Publication date: April 15, 2021Inventors: Kern Bhugra, August Anderson
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Publication number: 20210106489Abstract: An orthosis device for a subject and a rehabilitation system including the orthosis device includes a main housing assembly configured to be worn on an upper extremity of the subject and comprising a motor mechanism configured to actuate movement of at least one finger of the subject. A finger interface assembly is connected to the main housing assembly and configured to be secured to at least one finger of the subject and to induce, as actuated by the motor mechanism, flexion and extension motion of the at least one secured finger. The orthosis device is configured to leave unsecured to the orthosis device at least one finger that is not the at least one finger secured to the finger stay assembly.Type: ApplicationFiled: October 13, 2020Publication date: April 15, 2021Inventors: Kern Bhugra, August Anderson
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Publication number: 20210106490Abstract: A system for moving or assisting in movement of a body part of a subject, as well as a rehabilitation system including such a movement assistance system, includes a body part interface configured to be secured to the body part, and a motor-actuated assembly connected to the body part interface to move the body part interface to cause flexion or extension movement of the body part. A force sensing module is configured to measure forces applied between the body part interface and the motor-actuated assembly to ascertain at least one of volitional flexion and volitional extension movement of the body part by the subject, among other functions that may be implemented in movement assistance and rehabilitation systems using the disclosed force sensing module designs.Type: ApplicationFiled: October 13, 2020Publication date: April 15, 2021Inventors: Kern Bhugra, August Anderson
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Publication number: 20210106491Abstract: A cup holder assembly for a portable and handheld walking apparatus and having a fastener assembly with an annular clasp having an upper edge, defining an annular recess operably configured to selectively increase and decrease in diameter over a portion of a tubular framing structure of a portable and handheld walking apparatus, and having at least one hinge member assembly directly and hingedly coupled to the annular clasp and operably configured to rotate and have a locked position along a rotation path with respect to the upper edge of the annular clasp. A cantilevered support rod is coupled to the at least one hinge member assembly and a cylindrical container member with a container fastener directly coupled thereto and a portion of the cantilevered support rod disposed and compressively retained thereon, the bottom wall and the sidewall defining a cylindrical container cavity.Type: ApplicationFiled: October 15, 2019Publication date: April 15, 2021Inventors: Sherry D. Johnson, Shang M. Grange
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Publication number: 20210106492Abstract: An apparatus can include a left cover, sized and shaped to fit over a left eye of a patient to define a left cavity between the left cover and an anterior surface of the left eye and a right cover, sized and shaped to fit over a right eye of the patient to define a right cavity between the right cover and an anterior surface of the right eye. The apparatus can include a left pressure source to apply a left working fluid to the left cavity, the left pressure source capable of generating a left cavity pressure including a left negative gauge pressure and a right pressure source to apply a right working fluid to the right cavity, the right pressure source capable of generating a right cavity pressure including a right negative gauge pressure, where the right pressure source can be separate from the left pressure source.Type: ApplicationFiled: December 22, 2020Publication date: April 15, 2021Inventors: John Berdahl, George Tsai
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Publication number: 20210106493Abstract: An embodiment of a system for treating sleep apnea includes a collar, pump, motor, sensor, memory, and controller, which is configured to store, in the memory, information related to sleep-apnea events or sleep-apnea treatment, experienced by the subject. For example, the controller can obtain, and store in the memory, information related to sleep-apnea events, and the controller, or another computing system, can correlate this information with the subject's lifestyle choices, and can recommend lifestyle changes to improve the subject's sleep apnea. Furthermore, the controller can obtain and store, in the memory, information related to usage and settings of the sleep-apnea system, and the controller, or another computing system, can correlate this information with the subject's wellbeing, and can recommend changes in the usage or the settings of the sleep-apnea system that can improve the subject's wellbeing.Type: ApplicationFiled: September 22, 2020Publication date: April 15, 2021Applicant: Somne LLCInventors: Roderick A. Hyde, Kenneth G. Caldeira, Gary L. McKnight, Lowell L. Wood, JR., Dennis J. Rivet, Katherine A. Sharadin, Michael A. Smith
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Publication number: 20210106494Abstract: A health-regain device, includes a driving portion, a health portion disposed on one side of the driving portion, and a control module communicably connected to the driving portion, wherein the control module controls the driving portion driving the health portion in rhythmic reciprocating motion.Type: ApplicationFiled: December 3, 2020Publication date: April 15, 2021Inventor: Jiang WANG
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Publication number: 20210106495Abstract: An apparatus for generating a rotary reciprocating motion comprises an input shaft which is driven with unidirectional rotation and an output shaft for delivering reciprocating rotary motion. A first magnetic or ferromagnetic ring is disposed about a rotation axis fixed to the input shaft and a second magnetic or ferromagnetic ring is disposed about the rotation axis fixed to the output shaft. At least one is formed as an arrangement of permanent magnets. The first and second rings are disposed one within the other around the rotation axis. The magnetic coupling between the rings in combination with the effect of an output load results in the desired reciprocating motion of the output shaft.Type: ApplicationFiled: October 13, 2020Publication date: April 15, 2021Inventors: Gertrude van der Kamp, Pieter Johannes Bax, Theodoor Stolk, Hamid Ziaimehr
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Publication number: 20210106496Abstract: A medical device for lay rescuers and first aiders as part of “survival chain” in cardiac arrest scenario. The device gives audible feedback to its user regarding the adequate chest compression depth, based on American Heart Association (AHA) guidelines. In addition, it raises user's sense of capability and confidence in cases of cardiac emergencies.Type: ApplicationFiled: October 28, 2018Publication date: April 15, 2021Inventors: Udi NAKAR, Slav GAFT
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Publication number: 20210106497Abstract: Press-through packaging (10) has a front wall (20) and a rear wall (30) which are connected to each other along their longitudinal edges (40) and their transverse edges (50) and define a receiving space (60) for a, preferably solid, in particular one-piece, filling material. The front wall (20) and/or the rear wall (30) of the press-through packaging (10) is/are made from a film or a laminate, and the film or laminate has a, preferably mechanically produced, material weakening (70). Strip packaging (100) includes a plurality of press-through packages (10), and additionally includes a film or a laminate for producing the press-through packaging (10) or the strip packaging (100).Type: ApplicationFiled: May 18, 2018Publication date: April 15, 2021Inventors: Romina MALOVIC, Andreas GMEINDNER, Fabio DAIDONE
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Publication number: 20210106498Abstract: A vial jacket configured to receive a label. The vial jacket includes a plastic material having a cryogenic operating temperature range, a hinge formed in the plastic material, a locking mechanism, and an opening formed in the plastic material. The plastic material is dimensioned to surround at least a portion of a vial. The hinge defines a first half shell having a first edge and a second half shell having a second edge. The locking mechanism is configured to secure the first edge of the first half shell to the second edge of the second half shell. The opening has an axial length and a transverse length.Type: ApplicationFiled: October 6, 2020Publication date: April 15, 2021Inventors: Stephen Flores, Patricia M. Kessler
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Publication number: 20210106499Abstract: In certain embodiments, a vial adaptor comprises a housing configured to couple the adaptor with a vial, an access channel, a regulator channel, and a regulator assembly. The access channel is configured to facilitate withdrawal of fluid from the vial when the adaptor is coupled to the vial. The regulator channel is configured to facilitate a flow of a regulating fluid from the regulator assembly to compensate for changes in volume of a medical fluid in the vial. In some embodiments, the regulator assembly includes a flexible member configured to expand and contract in accordance with changes in the volume of the medical fluid in the vial. In some embodiments, the flexible member is substantially free to expand and contract. In some embodiments, the flexible member is not partly or completely located in a rigid enclosure.Type: ApplicationFiled: October 16, 2020Publication date: April 15, 2021Inventor: Thomas F. Fangrow
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Publication number: 20210106500Abstract: A device for dosing a product in capsules (12) or similar, comprising at least one dosing disc (36) which has dosing openings (38), and at least two filling stations (41-45) with which groups of dosing opening (38) are associated, wherein each filling station (41-45) comprises at least one tamping pin (51-55); the tamping pin (51-55) can plunge to a specified depth (h1-h5) into the dosing opening (38) to compress the product (17), and said tamping pin has at least one pressing means (71) for producing a variable pressure (p1-p5) with which each tamping pin (51-55) elastically deflects into the dosing opening (38); and at least one adjusting means, in particular an adjusting drive (61-65), is provided in order to adjust the depth (h1 to h5) for each of the two tamping pins (51-55) independently of one another.Type: ApplicationFiled: January 31, 2018Publication date: April 15, 2021Inventors: Werner Runft, Thomas Brinz, Bernhard Wagner
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Publication number: 20210106501Abstract: Teething devices include a flexible teething member having a hollow interior and partially defining a cavity. A swallow shield coupled with the flexible teething member has a hollow interior and partially defines the cavity. The swallow shield is configured to prevent swallowing of the teething device. A reservoir coupled with the swallow shield has a hollow interior partially defining the cavity. In some implementations an opening in the reservoir provides access to the cavity for introduction and removal of a liquid/gel therefrom, and a closure member is configured to couple with the reservoir in a liquid-tight configuration. In other implementations the cavity is permanently sealed with liquid/gel therein—the teething device including no opening to access the cavity. In implementations the flexible teething member forms a nipple shape. In other implementations it is shaped and sized to simultaneously contact all twenty deciduous teeth of an infant.Type: ApplicationFiled: March 21, 2020Publication date: April 15, 2021Applicant: Nippii LLCInventor: Ryan Paul Blake
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Publication number: 20210106502Abstract: A dental device is improved in its ability to produce hydroxyl apatite by having a layer of mineral trioxide aggregate (MTA) deposited thereon. A tile of MTA is prepared, heat treated and sintered to produce a micronized tile of MTA that can then be deposited by physical vapor depositions, hot isostatic pressing, molding or other conventional technique.Type: ApplicationFiled: December 7, 2020Publication date: April 15, 2021Applicant: DENTSPLY SIRONA, Inc.Inventors: Kevin Wilkinson, Geoffrey Ndungu
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Publication number: 20210106503Abstract: A photocurable dental impression material comprising: (a) a mixture of polymerizable silicone compounds each having two or more polymerizable (meth)acrylate groups, said mixture having a dynamic viscosity at 25° C. of from 1 to 100 Pas; (b) a filler; (c) a photo initiator system, wherein the mixture of polymerizable silicone compounds comprises based on the total weight of the mixture of polymerizable silicone compounds (a) 10 to 90 percent by weight of high-molecular polymerizable silicone compounds having a molecular weight in the range of from more than 4000 up to 10.000; and (b) 90 to 10 percent by weight of polymerizable silicone compounds having a molecular weight in the range of from 300 to 4000.Type: ApplicationFiled: March 7, 2019Publication date: April 15, 2021Applicant: DENTSPLY SIRONA Inc.Inventors: Joachim KLEE, Florian SZILLAT, Maximilian MAIER, Marjorie YON, Jacques LALEVÉE, Julie KIRSCHNER, Fabrice MORLET-SAVARY, Céline DIETLIN
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Publication number: 20210106504Abstract: A cosmetic wipe for applying or removing a cosmetic formula is described. In an embodiment, the cosmetic wipe includes a thin body. The cosmetic wipe also includes an edge of the body defining a perimeter of the body and a slit located in the thin body offset from the edge of the body. The slit may be configured to increase an edge length of the body.Type: ApplicationFiled: October 14, 2019Publication date: April 15, 2021Applicant: L'OrealInventor: William Bickford
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Publication number: 20210106505Abstract: The present invention relates to a droplet-releasing cosmetics material, in particular cosmetics material comprising a polyhedral complex containing: in cosmetics which release a droplet by rubbing, a) a polyhedral structure wherein an interior is composed with a plurality of plate-like materials and has a space therein; and b) droplets contained in a space inside the polyhedral structure. A cosmetics material according to the present invention releases a droplet by rubbing in use thereby having a visual effect and excellent feeling in sue and is silicone polymer-free type capable of solving the problem of side effects by the silicone polymer and the user's discomfort and has benefit of excellent stability in the cosmetic material of the polyhedral complex.Type: ApplicationFiled: April 3, 2018Publication date: April 15, 2021Inventor: Sung Ho LEE
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Publication number: 20210106506Abstract: The methods described herein provide self-assembling macromolecular networks within the human skin. The methods provide instant and accumulation-based physical properties within the skin, causing cosmetic benefits including, bulking/plumping, filling, strengthening, smoothing, firming, and lifting, as well as enhancing the optical properties, radiance and other cosmetic appearance characteristics of the skin. The disclosure also provides a method of re-structuring the skin without cellular biogenesis by effecting macrostructures within the skin. The method comprising effectuating self-assembly within the skin layers by topically applying a composition comprising at least one self-assembly material to form functional macrostructures within the skin and effectuating self-assembly of the at least one self-assembly material in vivo while substantially preventing self-assembly prior to the topical application or treatment.Type: ApplicationFiled: October 8, 2020Publication date: April 15, 2021Inventors: Kurt Matthew Schilling, Sierra Beck, Jaime Ann Emmetsberger, Melanie Ann Hutnick, Matthew Tyler Iovino, Jaimie Sabrina Jerome, Nevena Mladen Karaman-Jurukovska, Thomas Mammone, Fatemeh Mohammadi, Tsung-Wei Robert Mou, Elham Tavasoli
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Publication number: 20210106507Abstract: The problem to be solved by the present invention is to increase durability and suppress irregularities an oil-in-water type emulsion containing an agar microgel. A method for accomplishing this goal comprises dispersing in the makeup 0.5 to 10% by mass of a core-corona microgel. The resulting compositions are highly durable and excellent in feeling in use, and particularly excellent in freshness.Type: ApplicationFiled: October 12, 2020Publication date: April 15, 2021Applicant: SHISEIDO COMPANY, LTD.Inventors: Shun KUBOTA, Yurika WATANABE, Yuki SUGIYAMA
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Publication number: 20210106508Abstract: Cosmetic blending devices for producing a cosmetic liquid from a solid-shell cosmetic ingredient capsule. The cosmetic blending devices include a lid, a base, a blending element configured to blend the capsule, and a drive mechanism configured to actuate the blending element. The cosmetic blending device may include a thermal element configured to change a temperature of the capsule. The thermal element may melt the capsule. The solid-shell cosmetic ingredient capsule comprises a shell defining an enclosed inner volume, and cosmetic material included in the enclosed inner volume. Methods of using the cosmetic blending devices comprise placing the solid-shell cosmetic ingredient capsule into the cosmetic blending device and blending the capsule to produce the cosmetic liquid. Methods of forming the solid-shell cosmetic ingredient capsule comprise forming a portion of the shell, adding the cosmetic material to the portion of the shell, and forming the remaining portion of the shell.Type: ApplicationFiled: October 13, 2020Publication date: April 15, 2021Inventors: Robb Akridge, Gregory Calvin Peterson
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Publication number: 20210106509Abstract: The present invention relates to a sunscreen composition. Particularly, the sunscreen composition relates to providing improved ultraviolet A protection factor (UVAPF). The composition comprises UVA organic sunscreen, 2-ethylhexyl 2-cyano-3,3-diphenylacrylate, a compound selected from resorcinol, phenylethyl resorcinol, 4-alkyl substituted resorcinol and mixtures thereof, fatty acid and soap.Type: ApplicationFiled: April 15, 2019Publication date: April 15, 2021Applicant: Conopco, Inc., d/b/a UNILEVERInventors: Rajkumar PERUMAL, Ashish Anant VAIDYA
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Publication number: 20210106510Abstract: Disclosed is a composition including, per 100% of its mass: a) 60.0% to 75.0% by mass of an organic solvent (OS1) chosen from 1,2-propanediol, 1,3-propanediol, 1,4-butanediol, 1,3-butanediol, 1,2-butanediol, 2-methyl-2,4-pentanediol, 1,6-hexanediol, 1,8-octanediol, or a mixture of these compounds; b) 0.1% to 2.0% by mass of a composition (ES) including an amount by mass x1, expressed as mass equivalent of 1-O-(2-caffeoyl)maloyl-3,5-di-O-caffeoylquinic acid, of greater than or equal to 200 mg/g of a compound of general formula (I): in which Q1, Q2, Q3, Q4 and Q5 represent, independently of each other, a hydroxyl radical or a salt thereof or a radical chosen from caffeoyl, maloyl, caffeoyl maloyl and maloyl caffeoyl radicals, it being understood that at least one of these radicals Q1, Q2, Q3, Q4 and Q5 represents neither the —OH radical nor a salt thereof; and c) 20.0% to 35.0% by mass of water. Related treatments are also disclosed.Type: ApplicationFiled: April 10, 2019Publication date: April 15, 2021Inventors: Catherine KERN, Christine GARCIA, Christian GOMBERT, Philippe MSIKA
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Publication number: 20210106511Abstract: The present invention relates to topical compositions comprising at least one polar oil and a micronized 1,4-di(benzoxazol-2?-yl)benzene having a mean particle size of at most 300 nm as well as to the use of such a micronized 1,4-di(benzoxazol-2?-yl)benzene to reduce the transfer of such oils to surfaces.Type: ApplicationFiled: March 19, 2019Publication date: April 15, 2021Inventors: Christine MENDROK-EDINGER, Alexander SCHLIFKE-POSCHALKO
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Publication number: 20210106512Abstract: [Problem to be Solved] An object of the present invention is to provide an aqueous antimicrobial composition which exhibits excellent antibacterial and antifungal activities even at a low concentration and has high safety, low skin irritation, and excellent long-term stability. [Solution] Aqueous antimicrobial compositions comprising two or more compounds selected from (a) benzoic acid or a salt thereof, (b) ?-gluconolactone, (c) ketonic acid or a salt thereof, and (d) sorbic acid or a salt thereof; and at least one or more dicarboxylic acid represented by General Formula (I) or a salt thereof.Type: ApplicationFiled: March 28, 2017Publication date: April 15, 2021Inventors: Kazuhiko Sakata, Mayumi Furukawa
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Publication number: 20210106513Abstract: The invention provides an antimicrobial personal cleansing composition comprising: (i) an aqueous continuous phase including one or more anionic cleansing surfactants; (ii) a dispersed phase including dispersed particles of zinc pyrithione (ZPT); (iii) a structuring polymer for the aqueous continuous phase which is selected from crosslinked alkali-swellable acrylic emulsion (ASE) polymers; and (iv) from 3 to 20 wt % niacinamide based on the total weight of the composition, wherein the structuring polymer is selected from crosslinked copolymers of (meth)acrylic acid with one or more C1 to C5 alkyl esters of (meth)acrylic acid.Type: ApplicationFiled: March 22, 2018Publication date: April 15, 2021Inventors: Graham Andrew TURNER, Christopher Francis SMITH
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Publication number: 20210106514Abstract: Composition, preferably a cosmetic composition, for caring for and/or making up keratin materials, preferably the eyelashes and/or the eyebrows, comprising: —(1) at least one linear fatty acid monoester of formula (I): R1—O—R2 in which R1 and R2 are linear and saturated and have, independently of one another, a number of carbon atoms greater than or equal to 20, with R1 representing an acyl radical, and R2 representing an alkyl radical, and —(2) at least one fatty acid having from 14 carbon atoms to less than 20 carbon atoms, —(3) at least one organic base, in particular derived from an alkanolamine, capable of at least partially neutralizing at least one fatty acid (2), and —(4) at least one fatty alcohol preferably chosen from C14-C30 fatty alcohols, better still chosen from the linear and saturated C14-C24, even better still C14-C20, fatty alcohols, and —(5) water.Type: ApplicationFiled: April 16, 2019Publication date: April 15, 2021Applicant: L'OREALInventors: Odile AUBRUN, Stephane DOUEZAN, Mohamed BOULARAS, Maitena LEURIDAN, Philippe ILEKTI
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Publication number: 20210106515Abstract: The invention relates to a method for producing an extract of seeds of the Entada genus by selective hydrolysis of the metabolites accumulated in the seeds. The invention also relates to the extract produced using such a method, to a composition comprising such an extract, and to the cosmetic and dermocosmetic applications of such an extract.Type: ApplicationFiled: April 11, 2019Publication date: April 15, 2021Inventor: Marie-Christine SEGUIN
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Publication number: 20210106516Abstract: The present invention relates to an oral tablet for oromucosal delivery of biologically active compounds, the tablet comprising a sugar alcohol composition comprising one or more sugar alcohol particles in an amount of at least 20% by weight of the tablet, an ion-exchange composition comprising a plurality of particles of at least one water-soluble anionic mucoadhesive polymer loaded with a cationic biologically active compound.Type: ApplicationFiled: October 11, 2019Publication date: April 15, 2021Inventor: Kent Albin Nielsen
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Publication number: 20210106517Abstract: A method of manufacturing a nicotine-containing mucoadhesive film, by preparing an aqueous solution at a pH of from 9.5 to 13, said solution comprising (i) a nicotine salt, (ii) an alkaline pH-regulating agent, and (iii) a film-forming agent comprising an alginate salt of monovalent cation or a mixture of alginate salts of monovalent cations, the film-forming agent having a mean guluronate (G) content of from 50 to 85% by weight, a mean mannuronate (M) content of from 15 to 50% by weight, a mean molecular weight of from 30,000 g/mol to 90,000 g/mol and being such that a 10% aqueous solution thereof at a temperature of 20° C. has a viscosity of 100-1000 mPas, as measured at a shear rate of 20 rpm by use of a Brookfield viscometer with a spindle No. 2; distributing the solution onto a solid surface; and permitting the solution to dry on said surface. A nicotine-containing mucoadhesive film.Type: ApplicationFiled: September 18, 2020Publication date: April 15, 2021Inventor: Fredrik HUBINETTE
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Publication number: 20210106518Abstract: The present invention relates to an oral thin film comprising at least one polymer and at least one pharmaceutically active ingredient, the oral thin film being substantially U-shaped, and to the use of said oral thin film as a medicament, especially for sub-lingual administration.Type: ApplicationFiled: April 25, 2019Publication date: April 15, 2021Inventors: Christoph SCHMITZ, Marius BAUER, Michael LINN
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Publication number: 20210106519Abstract: The present invention relates to a topical formulation intended to be used for the treatment of androgenic or androgenetic baldness in men and women, with reduced side effects, especially with fewer collateral effects in the female population. The topical formulation comprises 0.01% to 10% by weight of Finasteride and a concentration of 1% to 5% by weight of Minoxidil in its free form or in an inert porous polymer. The combination of Finasteride and Minoxidil provides a synergistic effect against baldness. The formulation also comprises 0.15% by weight of retinol and is suitable for being applied to the scalp of the patient that requires it.Type: ApplicationFiled: January 31, 2019Publication date: April 15, 2021Applicant: CENTRO INTERNACIONAL DE COSMIATRÍA, S.A.P.I. DE C.V.Inventor: Sergio NACHT
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Publication number: 20210106520Abstract: The present disclosure describes a method of delivering a therapeutic agent providing a microneedle array including a plurality of microneedles, the plurality of microneedles including a conductive coating disposed thereon, wherein the conductive coating includes the therapeutic agent and a conducting polymer; implanting the microneedle array in a dura mater of a subject in need thereof, wherein the microneedle array pierces the dura mater; and applying an electrical stimulus to the microneedle array to provide a controlled release of the therapeutic agent from the conductive coating, across the dura mater, to the central nervous system of the subject.Type: ApplicationFiled: October 13, 2020Publication date: April 15, 2021Applicant: University of WashingtonInventors: Rajiv Saigal, Joyce Huang
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Publication number: 20210106521Abstract: A water-dissolvable compressed oral nicotine lozenge is disclosed, the oral nicotine lozenge comprising a first module and a second module, the first and the second modules being fused by compression, the first module being a lozenge module comprising at least one sugar alcohol and the second module being an FDT-module comprising at least one sugar alcohol and nicotine. Also, a method of manufacturing a water-dissolvable compressed oral nicotine lozenge is disclosed.Type: ApplicationFiled: October 11, 2019Publication date: April 15, 2021Applicant: Fertin Pharma A/SInventors: Dorthe Schackinger Boesen, Heidi Ziegler Bruun, Bruno Provstgaard Nielsen, Kent Albin Nielsen, Rikke Pranger-Rasmussen
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Publication number: 20210106522Abstract: The present disclosure provides for a method of administering bortezomib into a brain tumor by a pump implanted in a brain of a subject. Also encompassed by the present disclosure-is- a method of administering a drug to a tumor in a central nervous system of a subject, the method comprising, delivering a therapeutically effective amount of the drug into a brain, tumor by a pump implanted in a brain of the subject, wherein administration of the drag to the subject in the central nervous system is contraindicated because of toxicity of the drug.Type: ApplicationFiled: January 29, 2019Publication date: April 15, 2021Inventors: Thomas CHEN, Yehoshua SHACHAR
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Publication number: 20210106523Abstract: The present disclosure relates to formulations, methods, kits, and dosage forms for oral pharmaceutical formulations comprising one or more immunosuppressive agents. The pharmaceutical formulations of the present disclosure can be useful in treating organ or stem cell transplant recipients or T-cell mediated diseases.Type: ApplicationFiled: March 19, 2019Publication date: April 15, 2021Applicant: Gemini Laboratories, LLCInventors: Padam Bansal, Hardik Patel, Amitkumar Patel, Suhaskumar Patel
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Publication number: 20210106524Abstract: A liquid oral pharmaceutical dosage form, comprising pharmacologically effective amounts of at least one histamine H2-receptor antagonist in a hydrophobic/lipophilic liquid substantially free from water comprising at least one viscosity enhancing agent, and pharmacologically effective amounts of one or more antacid(s) in a liquid comprising at least one viscosity enhancing agent and at least one flavor, wherein the two liquids are physically separated from each other and wherein the two liquids have matching rheological profiles and a package comprising multiple liquid oral dosage forms as well as a method of treating a gastric disease or disorder by use of the liquid oral pharmaceutical dosage form.Type: ApplicationFiled: April 24, 2019Publication date: April 15, 2021Inventors: Salih Muhsin Muhammed, Katarina Lindell, Jill Nilgard, Sofi Nöjd