Abstract: The present invention relates to an improved heartbeat display and notification system. The system includes retrieving a stream of heartbeat data from an external heart monitoring device. The system further includes storing the retrieved stream of heartbeat data and rendering portions of the stored heartbeat data. Furthermore, the system includes displaying the rendered portions of the stored heartbeat data as a heartbeat rendering. The heartbeat display and notification system also includes determining, and when necessary, updating a user's baseline heart rate. Additionally, the system includes storing the user's baseline heart rate, comparing the user's present heart rate to the user's baseline heart rate. The system further includes generating a heartbeat rendering in response to the comparison and issuing a notification when the difference between the user's present heart rate and the user's baseline heart rate is beyond a pre-defined threshold.

Abstract: A medical monitoring method includes acquiring, using an implantable heart monitoring device implanted in a patient, an electrocardiogram (ECG) signal that is amplitude modulated (AM) by respiration of the patient. The AM ECG signal is analyzed to identify a respiratory pattern of the patient. The identified respiratory pattern is indicated to a user.

Abstract: This heart failure degree-of-exacerbation determination system comprises a storage device (11) and an arithmetic device (12). The arithmetic device (12) includes a heart failure degree-of-exacerbation determination means (121) for determining the degree-of-exacerbation of heart failure, on the basis of stored information which is stored in the storage device (11) and the correlation among a plurality of evaluation values which are associated with a acral portion of a patient.

Abstract: A method for intravascular image processing carries out steps of acquiring intravascular data of a portion of a lumen, determining a region of interest based on characteristics of the acquired data, determining an angle (orientation) for displaying an initial longitudinal view of the portion of the lumen based on the determined region of interest, and displaying the initial longitudinal view based on the determined angle and displaying a tomographic view of the portion of the lumen.

Abstract: Provided herein are medical sensors and related methods for measuring a real-time personal metric. The medical device may comprise an electronic device having a sensor comprising an accelerometer and a bidirectional wireless communication system electronically connected to the electronic device for sending an output signal from the sensor to an external device and receiving commands from an external controller to the electronic device.

Abstract: Disclosed is a method for calculating fractional flow reserve, comprising: collecting a pressure at the coronary artery inlet of heart by a blood pressure sensor in real-time, and storing a pressure value in a data linked table; obtaining an angiographic time according to the angiographic image, finding out the corresponding data from data queues based on time index using the angiographic time as an index value, screening out stable pressure waveforms during multiple cycles, and obtaining an average pressure Pa; and obtaining a length of the segment of blood vessel from angiographic images of the two body positions, and obtaining a blood flow velocity V; calculating a pressure drop ?P for the segment of the blood vessel using the blood flow velocity V at the coronary artery inlet, and calculating a pressure Pd at the distal end of the blood vessel, and further calculating the angiographic fractional flow reserve.

Abstract: An apparatus including: an imaging system; a probe for insertion into a vessel, the probe being coupled to the imaging system; a flow delivery system associated with the probe to release a differential-contrast fluid into the vessel at a location proximal to an end of the probe; and a processor to: collect data from the imaging system based on release of the differential-contrast fluid into the vessel, analyze the collected data to identify a presence or absence of the differential-contrast fluid as a function of time, and determine a flow rate in the vessel based on analyzing the collected data.

Abstract: Techniques for determining pulse transit time (PIT) and blood pressure measurements based on stethoscope data are provided. In one example, a system comprises a stethoscope component that monitors a heart and generates stethoscope data representative of a sound wave generated by the heart. The system can further comprise an analysis component that receives the stethoscope data and receives, from a photoplethysmography (PPG) component that monitors an extremity, PPG data representative of a pulse wave at the extremity. The analysis component can determine, based on the stethoscope data, a first time corresponding to closure of a tricuspid valve of the heart and can determine a PT as a function of the first time and a second time corresponding to the pulse wave at the extremity that is determined based on the PPG data. Blood pressure measurements can be obtained from algorithms with the inputs of PIT or times determined based on the PPG data.

Abstract: An electronic device and method are disclosed herein. The electronic device includes a display, a printed circuit board (PCB) disposed below the display and having a first surface facing the display, a biometric sensor disposed on the first surface of the PCB and configured to measure a biometric signal related to a heartbeat, a pressure sensor disposed below the display and configured to generate a pressure signal based on measuring a pressure applied to the display, a processor. The processor implements the method, including measuring, by the biometric sensor, the biometric signal, measuring, by the pressure sensor, the pressure applied to the display, calculating biometric information related to a heartbeat by interlinking the biometric signal and the pressure signal, and outputting the calculated biometric information to the display.

Abstract: A PPG PRV device for generating a PRV parameter of a PPG signal (20) as an estimation of a HRV parameter of an ECG signal. The PPG PRV device employs a PPG probe (700) and a PPG PRV controller (710). In operation, the PPG probe (700) generate a PPG signal (20). In response thereto, the PPG PRV controller (710) generates a normalized PPG signal (20?) including a plurality of pulses of the PPG signal (20) designated as normal pulses by the PPG PRV controller (710) and excluding at least one pulse of the PPG signal (20) designated at least one abnormal pulse by the PPG PRV controller (710), wherein the normalized PPG signal (20?) is HRV comparable to the ECG signal. The PPG PRV controller (710) derives the PRV parameter from a HRV measurement of the normalized PPG signal (20?).

Abstract: The present disclosure relates to a device, method and system for calculating, estimating, or monitoring the physiological parameters of a subject. At least one processor, when executing instructions, may perform one or more of the following operations. A first signal representing a pulse wave relating to heart activity of a subject may be received. A plurality of second signals representing time-varying information on the pulse wave may be received. A blood oxygen level of the subject based on the plurality of second signals may be determined. A first feature in the first signal may be identified. A second feature in one of the plurality of second signals may be identified. A pulse transit time based on a difference between the first feature and the second feature may be computed. A blood pressure of the subject may be calculated based on the pulse transit time.

Abstract: Techniques are provided for tracking heartrate metrics using different operating modes associated with different contexts of a wearable device. For example, a heartrate sensor of the wearable device may be operated in a first operating mode when an activity is being tracked within an application session of a particular application. The heartrate sensor may be operated in a second operating mode after detecting conclusion of the activity within the activity session (e.g., during sedentary time).

Abstract: A medical display processing device and a method of reusing data includes acquiring, over time via electrodes, electrical signals each acquired via one of the electrodes and indicating electrical activity at a location of a portion of patient anatomy in a 3D space. Electrical signal data, corresponding to the electrical signals, is filtered according to first filter parameter settings and first mapping information is generated for displaying a map of the portion of patient anatomy and the filtered electrical signal data. An indication of a region of the portion of patient anatomy on the map is received and second mapping information is generated for displaying, at the region on the map, a portion of the electrical signal data previously filtered from display.

Abstract: According to an aspect of the present disclosure, a hand held device is providing twelve lead ECG signals using fewer number of probes/electrodes comprising, a first electrode to sense electrical RH signal, a second electrode to sense electrical LH signal, a third electrode to sense electrical LL signal, a fourth electrode to sense electrical V1 through V6 signal in a sequence, a first electronic circuit operative generate a lead I, lead II and lead III ECG signal, a second electronic circuit to generate a CT signal from the lead I, lead II and lead III signal and a third electronic circuit operative to generate V1-V6 lead ECG signals from the electrical V1 through V6 signal and the CT signal.

Abstract: A system for heart monitoring including an electronic monitoring unit, a flexible carrier member, and a liner. The flexible carrier member includes a central void adapted to carry the electronic monitoring unit within the void and a back surface having a first connector component. The liner includes a back, adhesive surface, an opposing front surface, and a second connector component located on the front surface and adapted to secure to the first connector component of the flexible carrier member.

Abstract: The invention relates to a magnetic resonance imaging system (100) comprising a main magnet (104), a magnetic field gradient system with antenna elements (114), a radio-frequency system, a memory (136) storing machine executable instructions comprising a first set of machine executable instructions (150) for operating the magnetic resonance imaging system (100) in a pre-data-acquisition-mode in which data acquisition by the antenna elements (114) is switched off, and a processor (130) for controlling the magnetic resonance imaging system (100). An execution of the first set of machine executable instructions (150) causes the processor (130) to control the magnetic resonance imaging system (100) to generate in the pre-data-acquisition-mode acoustic sound using the magnetic field gradient system. The generation of the acoustic sound comprises generating an alternating gradient magnetic field by the magnetic field gradient system.

Abstract: Electrochemical Impedance Spectroscopy (EIS) is used in conjunction with continuous glucose monitors and continuous glucose monitoring (CGM) to enable in-vivo sensor calibration, gross (sensor) failure analysis, and intelligent sensor diagnostics and fault detection. An equivalent circuit model is defined, and circuit elements are used to characterize sensor behavior.

Abstract: A patient support device includes a patient support surface having a size to accommodate at least a part of the patient body, the device including at least one receptacle for housing a coil, which at least one receptacle is arranged in an area of the patient supporting surface corresponding to the position of the anatomic region to be imaged, the patient support surface being covered at least partially by one or more cushions covering in combination the entire patient supporting surface or at least a part of it. At least one of the receptacles for coupling to a receiving coil being provided on at least each of one or more than one of the said cushions, the coil once coupled to a corresponding receptacle is connected to a control and processing unit of the MRI apparatus by means of a cable which is external to the said patient support device.

Abstract: A magnetometer-based metal detection device and methods of use are described. The device includes a proximal portion, a central body and a distal portion, and at least one magnetometer positioned within or on the distal portion. The at least one magnetometer includes at least one sensor capable of sensing a magnetic field in three orthogonal axes. Also described is a method of calibrating the device to achieve rotational invariance, and a method of determining a directionality or directional line along which a target metal object lies.

Abstract: According to various, but not necessarily all, embodiments there is provided a respiratory volume measurement system. The respiratory volume measurement system comprises: at least one motion sensor and a machine learning system. The at least one motion sensor is configured to be placed on a chest wall of a subject to produce at least one sensor output signal dependent upon respiratory motion of the chest wall of the subject. The machine learning system is configured to receive at least the sensor output signal as an input and to produce at least a respiration measurement output, different to the sensor output signal, that provides at least a measure of respiration volume of the subject.

Abstract: An eye sensor, system and method for measuring fixational eye movements of an individual's eyeball (e.g., ocular microtremors and microsaccades) to provide a variable voltage biosignal for measuring the individual's brain stem activity. The eye sensor comprises a sensor mounted on the individual's closed or opened eyelid so as to be deflected by the fixational eye movements of the eyeball. A shielded flexible ribbon assembly supplies the biosignal generated by the sensor to an amplifier located on the individual's skin where the biosignal is amplified. The amplifier is interconnected with a signal processor and a display by which graphical and numerical representations of the biosignal are made accessible to an anesthesiologist, intensivist or clinician. A method for analyzing the biosignal to determine the brainstem activity of a patient.

Abstract: The present disclosure relates to systems and processes for monitoring a workout and for generating improved interfaces for the same. An electronic device displays a first user interface in response to initiating a workout session. In addition, the electronic device receives an input while displaying the first user interface, and in response to the input, ceases to display the first user interface and displays a second user interface associated with a music application of the electronic device.

Abstract: Embodiments of the invention provide optimized sputtered metallic surfaces adapted for use with implantable medical devices as well as methods for making and using such polymeric surfaces. These sputtered metallic surfaces have features that function to inhibit or avoid an inflammatory immune response generated by implantable medical devices. Typical embodiments of the invention include an implantable glucose sensor used in the management of diabetes having a sputtered metallic surface adapted to contact an in vivo environment.

Abstract: Disclosed herein are systems and methods for providing a compressible interconnect for allowing electrical communication between an electronics unit and an analyte sensor in an on-body analyte monitoring device. In other embodiments, systems and methods are provided for reducing the Z-height of an on-body analyte monitoring device by utilizing novel interconnects.

Abstract: A diagnostic Electrochemical Impedance Spectroscopy (EIS) procedure is applied to measure values of impedance-related parameters for one or more sensing electrodes. The parameters may include real impedance, imaginary impedance, impedance magnitude, and/or phase angle. The measured values of the impedance-related parameters are then used in performing sensor diagnostics, calculating a highly-reliable fused sensor glucose value based on signals from a plurality of redundant sensing electrodes, calibrating sensors, detecting interferents within close proximity of one or more sensing electrodes, and testing surface area characteristics of electroplated electrodes. Advantageously, impedance-related parameters can be defined that are substantially glucose-independent over specific ranges of frequencies. An Application Specific Integrated Circuit (ASIC) enables implementation of the EIS-based diagnostics, fusion algorithms, and other processes based on measurement of EIS-based parameters.

Abstract: Method for measuring the presence of a compound or a physiological parameter in the human or animal body, comprising positioning an intravaginal ring that comprises a sensor for the compound or parameter to be measured in contact with the vaginal mucosa and recording a signal produced by the sensor. It is further disclosed a method for the combined administration and measurement of compounds in the human or animal body, comprising the administration of one or more biologically active compounds and the simultaneous and/or subsequent measurement of the presence and/or concentration of the same and/or another compound and/or physiological parameter that is the result of the administration of the one or more biologically active compounds, wherein the measurement is performed with a sensor that is in contact with the vaginal mucosa.

Abstract: Systems, methods, and apparatuses for enabling a plurality of non-invasive, physiological sensors to obtain physiological measurements from essentially the same, overlapping, or proximate regions of tissue of a patient are disclosed. Each of a plurality of sensors can be integrated with or attached to a multi-sensor apparatus and can be oriented such that each sensor is directed towards, or can obtain a measurement from, the same or a similar location.

Abstract: A method, system, and device for improving the accuracy of a continuous glucose monitoring sensor by estimating a CGM signal at a time t+PH using a value of CGM at time t, using a real-time short-time glucose prediction horizon to estimate the real time denoised CGM value with a noise estimation algorithm.

Abstract: Various aspects of the present disclosure generally relate to a multispectral sensor device. In some aspects, a sensor device may obtain, from image data collected by a sensor of the sensor device, first image data regarding a first measurement location of a measurement target, and may obtain, from the image data, second image data regarding a second measurement location of the measurement target, wherein the first measurement location and the second measurement location are sub-surface measurement locations within the measurement target. The sensor device may determine, based on the first image data and the second image data, a pulse transit time measurement, and provide information identifying the pulse transit time measurement. Numerous other aspects are provided.

Abstract: An apparatus for insertion of a medical device in the skin of a subject is provided.

Abstract: A tail pressing type disposable safety lancet includes a shell, a lancet core, a spring and tail cover. The shell has an elastic arm for locking the lancet core, wherein: the tail cover has an active locking part for locking and the elastic arm has a passive locking part for locking correspondingly; the positions, the fitting time of the active locking part and the passive locking part correlate with the active and passive unlocking parts; when the tail cover is pressed during use, it forces the lancet core to unlock for ejection and puncturing, and the tail cover and elastic arm enter the locking state and cannot be used again. After use of the safety lancet, the tail cover permanently locks on the elastic arm of the shell, ensuring the safety of single use, and the user visually recognizes the tail cover is retracted at the tail of the shell.

Abstract: An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices. Embodiments include removing a substantially cylindrical cap from an inserter to expose a substantially cylindrical sleeve, removing a cover from a substantially cylindrical container holding sensor components, and fitting the sensor components into the inserter.

Abstract: A blood collection device may include a tubular container, which may include a closed end and an open end opposite the closed end. The blood collection device may include a plug sealing the open end and a partition within the tubular container. The partition may separate the tubular container into a first chamber and a second chamber. The first chamber and the second chamber may be evacuated such that a pressure within the first chamber and a pressure within the second chamber are lower than ambient pressure and equal to each other. In response to blood being drawn into the first chamber, the pressure within the first chamber may increase, and the partition may slide towards the closed end such that a size of the first chamber increases and a size of the second chamber decreases.

Abstract: A needle assembly. The needle assembly enabling the analysis of fluid trapped in a flashback chamber after an insertion needle has been inserted into a patient's vein.

Abstract: A system (100) for determining emotional or psychological state includes a human-multimedia interaction system (102) and a detector (104). The human-multimedia interaction system (102) includes a head mounted apparatus (1021) with a display device (1023), a processing device (1025), and a storage device (2026). The detector (104) detects at least one characteristic of a wearer. The processing device (1025) receives the characteristic of the wearer and compares the characteristic of the wearer with existing data in the storage device (2026) or from the cloud. When the characteristic of the wearer is determined or verified by the processing device (1025), the processing device (1025) transmits at least one of the video content signals, according to the characteristic of the wearer to the display device (1023) and the display device (1023) displays the video content signal.

Abstract: A method to handle urine includes collecting urine using a pad or garment; exposing the urine to an aluminum alloy to generate hydrogen gas and heat in an exothermic reaction; and storing the hydrogen in a sealed chamber.

Abstract: In a microrunner structure, there are provided with components for a cleaning procedure required to conduct electrochemical sensing when a biosensor is activated for sensing; and a urine signal detection device that is a SoC (System on a Chip), which has a wireless transceiving circuit for receiving a urine measurement method and channel information transmitted from an intelligent device, and in turn, outputting a stimulus signal to trigger a biosensor or a non-biosensor in a multi-channel structure to conduct urine sense processing for a sensing area, as well as transmitting detection processing for a concentration of urine substances from the electrochemical sensing to the intelligent device through the wireless transceiving circuit to assess a risk index between a heart disease or diabetes and a kidney disease.

Abstract: A disposable vital signs monitor patch includes hydrogel based conductive adhesives which contacts skin. A medical tape bonds to the skin and has printed silver-silver chloride electrodes. The hydrogel based conductive adhesives interact between the skin and the printed silver-silver chloride electrodes. A double-sided medical tape bonds to the medical tape. A printed circuit board assembly (PCBA) includes a vital signs sensor, a flexible battery, a light emitting device (LED), connects to the printed silver-silver chloride electrodes, and bonds to the double-sided medical tape. A polyethylene foam includes a cut-out for the flexible the LED. The PCBA bonds to the polyethylene foam layer. A plunger operates within a cut-out on the polyethylene foam layer. An acrylic adhesive transfer tape bonds to the acrylic adhesive transfer tape. The medical tape, the double-sided medical tape, the polyethylene foam, and the acrylic adhesive transfer tape bond to seal against environmental exposure.

Abstract: An emergency cardiac and electrocardiogram (ECG) electrode placement device is disclosed herein. The emergency cardiac and electrocardiogram (ECG) electrode placement device incorporates electrical conducting materials and elastic material into a pad that is applied to a chest wall of a patient, which places multiple electrodes in the appropriate anatomic locations on the patient to quickly obtain an ECG in a pre-hospital setting.

Abstract: A catheter has improved position and/or location sensing by using single axis sensors mounted directly along a portion of the catheter whose position/location is of interest. The magnetic based, single axis sensors are provided on a single axis sensor assembly, which can be linear or nonlinear. The catheter may include a catheter body on which at least one, if not at least three single axis sensors, are mounted serially along a length of the body. In one embodiment, the magnetic-based sensor assembly includes at least one coil member wrapped on the catheter body, wherein the coil member is connected to a respective cable member adapted to transmit a signal providing location information from the coil member to a mapping and localization system.

Abstract: Methods and/or device facilitating and selecting among multiple modes of filtering a cardiac electrical signal, in which one filtering mode includes additional high pass filtering of low frequency signals, relative to the other filtering mode. The selection filtering modes may include comparing sensed signal amplitude to one or more thresholds, using the multiple modes of filtering. In another example, an additional high pass filter is enabled, over and above a default or baseline filtering mode, and the detected cardiac signal is monitored for indications of possible undersensing, and/or for drops in amplitude toward a threshold, and the additional high pass filter may be disabled upon finding of possible undersensing or drop in signal amplitude.

Abstract: Methods and apparatuses, including devices and systems, for remote and detection and/or diagnosis of acute myocardial infarction (AMI). In particular, described herein are handheld devices having an electrode configuration capable of recording three orthogonal ECG lead signals in an orientation-specific manner, and transmitting these signals to a processor. The processor may be remote or local, and it may automatically or semi-automatically detect AMI, atrial fibrillation or other heart disorders based on the analyses of the deviation of the recorded 3 cardiac signals with respect to previously stored baseline recordings.

Abstract: The present disclosure generally relates to user interfaces for health monitoring. Exemplary user interfaces for initial setup of health monitoring using a first electronic device and a second electronic device is described. Exemplary user interfaces for recording biometric information for use in health monitoring is described. Exemplary user interfaces for using an input device while recording biometric information for health monitoring is described. Exemplary user interfaces for viewing and managing aspects of health monitoring is described.

Abstract: A system for configuring an ambulatory medical device includes an ambulatory medical device configured to monitor at least one electrocardiogram signal received from a patient for an occurrence of one or more cardiac events. The system also includes a remote computing device configured to receive a set of threshold values related to operation of the ambulatory medical device. The threshold values identify one or more conditions indicative of an occurrence of one or more cardiac events. The remote computing device is configured to query a master lookup table to determine a lookup code associated with the received set of threshold values, establish a communication link with the ambulatory medical device, receive an activation notification indicating that the ambulatory medical device has been activated, and encode a key. The encoded key includes the lookup code. The remote computing device is configured to transmit the encoded key to the ambulatory medical device.

Abstract: An electronic device to acquire and analyze electroencephalogram data of the subject includes a cognitive function examination control section that presents examination data used for a cognitive function examination of the subject at the time of executing an operation having a different purpose from that of an electroencephalogram measurement, and a cognitive function analysis section that extracts an index of a cognitive function of the subject from electroencephalogram data of the subject measured when presenting examination data.

Abstract: A method for determining a state of concussion or sub-concussion of an individual by measuring using a monitoring device a plurality of baseline heart rate variability data over a first period of time. The monitoring device transmits said baseline heart rate variability (HRV) data to an application on a smart device. The baseline HRV data is transmitted by said smart device said baseline heart rate variability data to a memory. The monitoring device measures a plurality of contact activity heart rate variability data over a second period of time and transmits the contact activity heart rate variability data to the smart device. The smart device transmits said contact activity heart rate variability data to a memory.

Abstract: A measuring device includes a stimulation instructing unit and an estimating unit. The stimulation instructing unit is configured to instruct a stimulating device to generate a plurality of stimulations corresponding to at least three fiducial points of brain anatomy data, the at least three fiducial points having been defined in the brain anatomy data. The estimating unit is configured to estimate, based on sensor output signals output from sensors configured to measure a brain activity signal of a subject who is a target to be measured, parts where brain activities occur due to the plurality of stimulations.

Abstract: A medical diagnostic device (100) in different embodiments uses a headband (204) and a beanie cap (304) configured to be affixed about the head of a subject for conducting measurements for diagnosing whether the subject is at risk of a concussion. A transducer (302) determines magnitude of impact on the head of the subject provides deceleration information associated with magnitude of the force via a pressure waveform. An accelerometer (402) in connectivity with a gyroscope (602) provide directional and angular information to determine probability of risk of a concussion. Bluetooth (404 or WiFi (406) connectivity enable different transmission modes of output signals from device (100) to device capable of performing the calculated metrics and providing a digital putout.

Abstract: The present invention is directed to movement disorder determination systems and methods. The systems and methods involve a mobile device and a computer system communicating with each other over a communications network. The mobile device is implemented with a pattern receiving and conversion software application and the computer system is implemented with a pattern processing software application. The pattern receiving and conversion software application and the pattern processing software application are configured to determine whether an individual has a movement disorder and the severity of the disorder if he does from a trace produced by the individual over a pattern such as an Archemidal spiral. The pattern processing software application processes the user trace to make the determination and informs the user the result of its determination.

Abstract: Provided is a method and apparatus for predicting a posttraumatic behavior problem that may predict a posttraumatic violent behavior problem of an individual, in detail, that may determine a biological phenotype of an individual experiencing a traumatic event within a predetermined period after the individual is exposed to the traumatic event, predict a violent symptom presentation probability of the individual based on the biological phenotype of the individual, and suggest an objective basis for preventive intervention in a development of posttraumatic stress disorder (PTSD) of the individual based on a prediction result.