Abstract: An image pickup apparatus for endoscope includes an image sensor, a ferrule which is a rectangular parallelepiped having a front surface, a rear surface, and four side surfaces and includes insertion holes and trenches parallel to the insertion holes on respective two side surfaces orthogonal to each other among the four side surfaces, an optical element in which a light emitting region is disposed in a position opposed to the insertion holes, and optical fibers inserted into the insertion holes.

Abstract: The invention includes devices, arrangements and methods for treating an endoscope after use to prevent adhesion of bioburden on internal walls of a lumen of the endoscope. After treatment, the device is stored in the treated condition until cleaning. The device is configured to selectively deliver cleaning solution to the endoscope. The device can be a circulating embodiment having a pump. A filter can be provided to filter debris during circulation. The device can be a non-circulating embodiment having a hydrophobic filter for release of air. Fittings are provided on the device components to selectively attach the device to endoscopes.

Abstract: In accordance with at least one embodiment of the present disclosure, a system includes an imaging instrument with a shaft including a proximal end, a distal end, and a lens at a distal end portion of the shaft. The system also includes a collar at a proximal end portion of the shaft. A cleaning device coupled to the imaging instrument includes a tubular member sized to receive the shaft of the imaging instrument. The cleaning device also includes a latching element coupled to the tubular member and configured to couple to the collar to retain the tubular member on the shaft of the imaging instrument and maintain a relative rotational relationship between the tubular member and the shaft of the imaging instrument. Devices and methods relate to cleaning devices for imaging instruments.

Abstract: A method and apparatus for warming an optical scope prior to in-in vivo disposal wherein a thermally conductive material is received into a chamber and is then heated in order to conduct the heat to a tip-portion of the optical scope. A perimeter about tip-portion of the optical scope is sealed to prevent migration of the thermally conductive material through the orifice one the optical scope is inserted into the chamber.

Abstract: The invention describes a videolaryngoscope that comprises: a hollow handle with a proximal end and a distal end; a mounting base for a video laryngoscope blade, the mounting base being rotatably connected to the distal end of the handle and having a distal end; a videocamera mounted on the distal end of the mounting base for the video laryngoscope blade; a head mounted on the proximal end of the handle; a screen housed in the head with rotary movement relative to the proximal end of the handle and angular movement from top to bottom, which communicates operationally with the video camera; a coil receiving a charge by induction, located in the head; a rechargeable internal power source operationally connected with the charge-receiving coil; and a charging base that couples with the head.

Abstract: Components for an endoscopic vessel harvesting system suitable for harvesting target vessels such as the saphenous vein or radial artery for cardiac artery bypass graft surgery. The main components of such systems include a vessel dissector and a vessel harvester, both of which work in conjunction with a separately provided endoscope. The vessel dissector is an elongated cannula having a blunt tip for separating layers of facial around vessels. The tip may be movable, and is typically transparent to permit viewing forward of the tip using the endoscope. Internal features of the tip may reduce glare back to the endoscope. Several devices improve visibility through the tip by reducing interference from tissue or fluid on the tip. The vessel harvester also has an elongated cannula for receiving the endoscope. Several tools within the harvester permit manipulation, severing, and sealing of vessels forward of the distal end.

Abstract: An Ocular Force Measuring Apparatus (OFMA) is provided. The OFMA can include a lens manipulator arranged on a carrier operably connected to a strain gauge load cell. The OFMA can be manipulated by hand or with an actuator mechanism. When the lens manipulator is engaged with a contact lens attached to an eye, the strain gauge load cell can measure the force required to remove the contact lens from the eye. Conversely, if a contact lens is arranged on the lens manipulator, the force required to deposit the contact lens on the eye is measureable by the strain gauge load cell.

Abstract: Disclosed is an optical coherence tomography system for ocular diagnosis.

Abstract: A method of testing a subject for impairment includes presenting an object to the subject and measuring gaze positions of the subject. The method further includes generating, using the measured gaze positions, a plurality of values of a gaze metric. The method further includes generating a cognition metric for the subject based on one or more of the group consisting of: a measure of a skewness of a distribution of the plurality of values of the gaze metric; and a measure of kurtosis of the distribution of the plurality of values of the gaze metric. The method further includes determining whether the cognition metric is indicative of cognitive impairment; and generating a report, based at least in part on the determination of whether the cognition metric is indicative of cognitive impairment, indicating the presence or absence of cognitive impairment.

Abstract: The present invention relates to a method for classifying a fundus image and a device using same. Specifically, according to the method of the present invention, a computing device acquires a fundus image of a subject, generates classification information of the fundus image, generates an interpretation text on the basis of the classification information, and provides the interpretation text to an external entity.

Abstract: Disclosed is a detector device for measuring and displaying clinical values in instantaneous mode. It is obtained from the printing of a sensor (on a thin rigid plastic support substrate, from here with the sensor constrained to the substrate, once the detector is positioned on the skin the device is characterized by elasticity and elongation. The clinical parameter detector includes: a rigid plastic support, a mechanism for acquiring, processing and transmitting the readings taken in digital mode, an adhesive component that fixes the acquisition, processing and transmission device to the rigid plastic support and an external patch-like component. An antenna is provided that allows the device to detect clinical values to interface via a wireless NFC connection with an external display device. This wireless NFC connection provides power to the detector device.

Abstract: The present invention provides a combined radiotherapy and MRI system in which an imaging coil is mounted on a mechanical arm. The position of the imaging coil is thus known and in embodiments can be controlled to prevent collisions with the patient and unfavourable interactions between the imaging coil and the radiation beam.

Abstract: The illuminator device for medical examination described herein employs a housing incorporating a magnified viewing lens having a lens polarizer and an array of LEDs to provide light for the viewing organic tissue and other matter. A switch is provided to communicate with a microprocessor that controls an LED driver adapted initiate to provide modes of operation that provide certain of the LEDs being illuminated in different modes. In operation the device incorporates at least five modes of operation. A first mode provides activating only polarized white lights, a second mode provides activating only ZWB2 bandpass filtered 365 nm UV LEDs, a third mode provides activating only ZWB2 bandpass filtered 385 nm UV LEDs, a fourth mode provides activating only unfiltered 405 nm UV LEDs and a fifth mode comprises activating only ZWB2 bandpass filtered 365 nm UV LEDs and ZWB2 bandpass filtered 385 nm UV LEDs. The device additionally incorporates an auxiliary magnifier that stores in the device handle.

Abstract: Methods and systems are provided for the detecting and presenting of faint signals from a real-time interactive imager. A real-time view of a subject is controlled by a user by entering commands that move the subject or a camera used to record the real-time view. The rate of this movement is monitored, and when the rate descends below a preset value, a trigger is sent to the camera. In response to the trigger, the camera switches to a lower frame frequency for capturing the real-time view of the subject, thereby increasing the amount of light collected in each frame, and increasing the sensitivity of the camera to faint signals. The methods and systems are particularly relevant for surgical or biopsy imaging, in which both a higher frame rate preview image of a subject for 3D visualization, and a higher sensitivity fluorescence image of the subject for tumor margin assessment, are desired.

Abstract: Arrangements, apparatus, systems and systems are provided for obtaining data for at least one portion within at least one luminal or hollow sample. The arrangement, system or apparatus can be (insertable via at least one of a mouth or a nose of a patient. For example, a first optical arrangement can be configured to transceive at least one electromagnetic (e.g., visible) radiation to and from the portion. A second arrangement may be provided at least partially enclosing the first arrangement. Further, a third arrangement can be configured to be actuated so as to position the first arrangement at a predetermined location within the luminal or hollow sample. The first arrangement may be configured to compensate for at least one aberration (e.g., astigmatism) caused by the second arrangement and/or the third arrangement. The second arrangement can include at least one portion which enables a guiding arrangement to be inserted there through.

Abstract: An injection sensing device (ISD) (e.g., wearable patch) is paired with an external device (e.g., a medication delivery pen and/or smart phone, iPad, computer) via wireless link or wireline connection. The ISD senses fluctuations in local skin temperature during an injection and provides to the external device captured data from the sensor relating to medicine delivery to a patient to ensure complete delivery and minimize MDD misuse or malfunction or inaccuracies in dosing. The ISD or external device can use captured data and corresponding time stamps to determine flow informatics such as flow rate, total dose delivered, and dose completion status. An LED on the ISD indicates delivery in progress and/or delivery completion.

Abstract: An apparatus for measuring a target tissue temperature is provided. The sensor antenna may include an outside and a contact side. A sensor antenna measurement aperture may be disposed on the contact side. The sensor antenna measurement aperture may be configured to generate a first signal. A skin temperature sensor may be disposed on the contact side and configured to generate a second signal. A radiometer may be configured to receive the first signal and the second signal.

Abstract: A method for detecting tissue abnormality in a tissue sample, comprising: illuminating a tissue sample in vivo with a first light beam having a wavelength selected from the range 390-430 nanometer (nm); applying contrast agent to the tissue sample; capturing a one or more images of the tissue sample; and detecting tissue abnormality based on at least one of color changes in the tissue sample and blood vessel features in the tissue sample appearing in said one or more images.

Abstract: A pulse rate and respiratory rate measuring method includes acquiring a facial image comprising a face of a user, calculating a color signal from a predetermined number of skin regions of interest in the face of the user in the facial image, calculating a pulse wave signal or a respiratory signal by converting an extracted signal into a time domain after extracting a signal in a frequency band corresponding to pulse or respiration in frequency data obtained by converting the color signal into a frequency domain, and measuring a pulse rate or a respiratory rate corresponding to the frequency band based on peak interval information in the pulse wave signal or the respiratory signal.

Abstract: The present disclosure relates to a method for vascular imaging and determining dynamic vascular parameters of blood flow. According to an embodiment, the present disclosure relates to an apparatus and method of determining dynamic vascular parameters of blood flow, comprising acquiring two-dimensional projection images of a vascular region of interest at a predetermined frequency, the vascular region of interest being downstream of a site of vascular administration of a radio-opaque medium, identifying, within the acquired two-dimensional projection images, heterogeneities of the radio-opaque medium, and determining the dynamic vascular parameters of the blood flow based on spatial movements of the identified heterogeneities of the radio-opaque medium. In an embodiment, the predetermined frequency is greater than 100 Hz.

Abstract: A computer-implemented method for providing a blood flow parameter set for a vascular malformation includes receiving time-resolved image data. The image data maps a change over time in a vessel section of an examination subject. The vessel section includes the vascular malformation. A time-resolved image of the vessel section is reconstructed from the image data. The vascular malformation is segmented in the image of the vessel section. An afferent and an efferent vessel are identified at the vascular malformation based on the image of the vessel section. An average blood flow velocity parameter and a vessel cross-sectional area parameter are determined for each of the afferent and the efferent vessel. The method includes determining and providing the blood flow parameter set for the vascular malformation based on the average blood flow velocity parameters and the vessel cross-sectional area parameters.

Abstract: An intravascular pressure sensor assembly is disclosed herein that is produced in part using photolithography and DRIE solid-state device production processes. Using DRIE production processes facilitates a number of features that could not be readily incorporated in sensor chips fabricated using mechanical saws. In accordance with a first feature, sensor chips are created with non-rectangular outlines. The sensor chip includes a widened portion that substantially abuts an inner wall of a sensor housing, and a cantilevered portion that is relatively narrow in relation to the widened portion. The non-rectangular outline of the sensor chip is formed using photolithography in combination with DRIE processing. In accordance with another feature, the sensor chip is positioned width-wise in the housing, thereby reducing a required length for the housing.

Abstract: The disclosed subject matter includes a wearable device for cuffless blood pressure monitoring that does not require external per-person calibration, such as with a cuff-based measurement device. The embodiment employs photoplethysmography sensors to obtain pulse wave velocity and develops compensation for external pressure influences.

Abstract: A belt providing improved durability and a blood pressure measurement device. A second belt of a belt of a blood pressure measurement device includes a second belt body constituted in a band-like shape using a resin material and including a plurality of small holes formed along a longitudinal direction, and a second insert being disposed in the second belt body and including a plurality of holes with a plurality of the small holes disposed on an inner side of the respective holes, a cross section of a portion of the second insert, which is between two adjacent holes and orthogonal to a width direction of the second belt body, being constituted like a trapezoid with a short side being disposed on a living body side, and the second insert being formed of a material having a higher tensile strength than the resin material constituting the second belt body.

Abstract: Devices, systems, and methods to determine fractional flow reserve. At least one method for determining fractional flow reserve of the present disclosure comprises the steps positioning a device comprising at least two sensors within a luminal organ at or near a stenosis, wherein the at least two sensors are separated a predetermined distance from one another, operating the device to determine flow velocity of a second fluid introduced into me luminal organ to temporarily displace a first fluid present within the luminal organ, and determining fractional flow reserve at or near the stenosis based upon the flow velocity, a mean aortic pressure within the luminal organ, and at least one cross-sectional area at or near the stenosis. Devices and systems useful for performing such exemplary methods are also disclosed herein.

Abstract: Methods and systems suitable for obtaining information related to at least one of: respiration rate, heart rate, respiration rate variability, heart rate variability, temporal characteristics of at least a part of a heartbeat, temporal characteristics of at least a part of a respiration cycle, or a duration of a time interval of propagation of a blood pressure pulse from a first point or area or part of a body to a second point or area or part of the body, in a non-contact fashion.

Abstract: Measuring device for measuring physiological data of an animal such as a mammal for determining at least one condition parameter of the animal, comprising a first and second module (12,14) which are configured to be worn, in use, by the animal, wherein the first and second module are furthermore configured for them, from a condition of being mechanically separated from each other, to be mechanically connected with each other whereby in the connected condition, in use, between the first and second module is a skin part of the animal, wherein one of the modules comprises a source (122) for emitting electromagnetic radiation such as light (L) and wherein another one of the modules comprises a sensor system (142) for measuring a parameter such as intensity of a fraction (Lm) of the emitted radiation (L) received via that skin part and for generating a measuring signal (SL) which is indicative of the measured parameter, wherein the measuring device is configured such that, in use, the first and second module can p

Abstract: A device may obtain raw heartbeat data associated with a plurality of wavelength channels. The device may generate, based on a feature vector transformation, a plurality of feature vectors, each corresponding to a respective one of the plurality of wavelength channels. The device may identify a set of selected feature vectors, from the plurality of feature vectors, based on a plurality of squares of correlation coefficients, each associated with a respective pair of the plurality of feature vectors. The device may generate, based on a principal component analysis, an average feature vector of the set of selected feature vectors. The device may determine initial heartbeat cycle data based on the average feature vector. The device may correct heartbeat cycle gaps in the initial heartbeat cycle data in order to determine final heartbeat cycle data.

Abstract: Disclosed are a universal cognitive state decoder based on a brain signal and a method and apparatus for predicting an ultra-high performance complex behavior using the same. The method of predicting a complex behavior may include configuring a high-level cognitive state decoder based on a brain signal for classifying a human's high-level core cognitive state, configuring a universal cognitive state decoder by including a calculated value of the high-level cognitive state decoder in another cognitive state decoder as an input value, and predicting a human's complex behavior using the universal cognitive state decoder.

Abstract: A system for providing a standard electrocardiogram (ECG) signal for a human body using contactless ECG sensors for outputting to exiting medical equipment or for storage or viewing on a remote device. The system comprises a digital processing module (DPM) adapted to connect to an array of contactless ECG sensors provided in a fabric or the like. A selection mechanism is embedded into the DPM which allows the DPM to identify body parts using the ECG signals of the different ECG sensors and select for each body part the best sensor lead. The DPM may then produce the standard ECG signal using the selected ECG signals for the different body parts detected. The system is adapted to continuously re-examine the selection to ensure that the best leads are selected for a given body part following a movement of the body part, thereby, allowing for continuous and un-interrupted ECG monitoring of the patient.

Abstract: Apparatuses, systems, and methods are disclosed for noninvasive medical diagnostics using electrical impedance metrics and clinical predictors. An apparatus includes a probe comprising an interrogation electrode that is configured to measure electrical impedance of tissue of a patient's body between the interrogation electrode and a reference electrode. An apparatus includes a processor and a memory that stores code executable by the processor to apply, noninvasively, an electrical current to the tissue of the patient's body using the interrogation electrode of the probe, measure electrical impedance of the tissue of the patient's body between the interrogation electrode of the probe and the reference electrode, and detect a presence of a malignant tumor in the tissue of the patient's body by inputting the measured electrical impedance of the tissue into machine learning. The machine learning is trained on patient data associated with a type of disease that is being diagnosed.

Abstract: A system for detecting tumoral masses in an unknown tissue is described, that can be coupled to an MRI system for receiving a number of unknown tissue scans, each scan comprising a corresponding plurality of MRI images relating to a group of voxels, each voxel being associated with a corresponding portion of unknown tissue, the MRI images of each scan being indicative of values of at least a corresponding initial parameter. The detection system determines for each voxel a corresponding probability value, indicative of the probability of the corresponding portion of unknown tissue including a corresponding tumoral portion. Furthermore, the detection system determines, for a plurality of voxel groups, a corresponding group aggressiveness value, indicative of the aggressiveness of the tumoral mass formed by the tumoral portions present in the corresponding portions of unknown tissue.

Abstract: A method for magnetic resonance imaging (MRI) tag tracking includes: synthetically generating tagged data from natural images combined with programmed tag motion and a full Bloch simulation; training a convolutional neural network (CNN) with the synthetically generated tagged data to generate grid tag motion paths; acquiring MRI images using a tagged imaging method; inputting the acquired images into the CNN to estimate motion paths of tracked points; and determining from the estimated motion paths a path of tag lines through the cardiac cycle from a set of tagged MRI images. The method can calculate strain curves from the estimated motion paths using Ecc derivation.

Abstract: A method for locating a variation in one or more electrical impedance properties of an object, the method comprising the steps of: (i) obtaining electrical impedance data for the object at different locations; (ii) analysing the obtained electrical impedance data using a transfer function of an assumed electrical model to determine a variation of a plurality of electrical impedance properties for the object with location; and (iii) identifying a location identified by a variation of one or more of the plurality of electrical impedance properties.

Abstract: A component analyzing apparatus is provided. The component analyzing apparatus includes: an impedance measurer including: a plurality of electrodes having an electrode width that is determined based on an effective measurement depth for analyzing a component of an analyte and a gap between two electrodes among the plurality of electrodes, and an electrode controller configured to apply a first current to a first electrode and a second electrode among the plurality of electrodes and configured to measure impedance based on a voltage between a third electrode and a fourth electrode; and a processor configured to analyze the component of the analyte based on the impedance measured by the electrode controller.

Abstract: Described is a system and medical device for the electromagnetic tracking of a medical instrument transported through a medical device, the medical device having a central axis, a channel that receives and transports a medical instrument through the medical device, the channel extending to a distal portion of the medical device. According to some aspects, the system includes tracking circuitry and a plurality of coordinated electromagnetic sensors for generating a virtual axis of travel for the medical instrument. According to some aspects, the virtual axis passes through the opening of the device and is aligned with a tool insertion axis.

Abstract: The invention relates to a device for superimposing known patterns, characteristic of a region, on (real) images of said region. The device comprises, a memory in which patterns are stored, which are representative of a selected region, of known position and orientation with relation to a common reference and processing means, for determining a pattern representative of the selected portion in the memory, on receipt of the designation of at least one portion of an observed image of the selected region, taken at a selected angle and at least one representative attribute of said region, taking account of the attribute selected, then superimposing the determined pattern on the selected portion of the image taking account of the selected angle.

Abstract: The present disclosure is directed to methods and systems that analyze one or more analytes in a fluid, such as breath, emitted from a user. The methods and systems can detect one or more analytes in the breath of a user to provide alerts in response to discrepancies in medications taken by a user, verify one or more medications taken by a user, manage a medication regime of a user, and various other functions disclosed herein.

Abstract: A lighting device, comprises a light source configured to provide a low Cyanosis Observation Index (COI) white light having a total flux, the light source comprising a first group of LEDs configured to provide a wide blue light, a second group of LEDs configured to provide a wide green light, and a third group of LEDs configured to provide a wide red light, wherein the low COI white light is a combination of at least the wide blue light, the wide green light, and the wide red light, wherein a current provided to the light source is distributed among the first group of LEDs, the second group of LEDs, and the third group of LEDs such that the wide blue light contributes 7 percent to 9 percent of the total flux, the wide green light contributes 62 percent to 76 percent of the total flux, and the wide red light contributes 20 percent to 26 percent of the total flux, and wherein a COI of the low COI white light is less than 1.

Abstract: A body measurement device and a method for controlling the same are disclosed. The body measurement device comprises a TOF camera capturing a first image that includes an RGB image and a depth image; a display displaying a graphic image; and a controller estimating a user's pose based on the first image, controlling the TOF camera to automatically capture a second image, which includes the user's body image in front of the camera, if the user's pose is a first pose, generating the user's body line image based on the captured second image, measuring the user's body size based on the generated body line image; and controlling the display to display the user's body size.

Abstract: The invention relates to a cardiac device comprising an accelerometer (4) and a filter (6) arranged to eliminate noise from an SCG signal from the accelerometer (4), as well as a computer (8) arranged to apply a thoraco-cardiovascular model to the signal from the filter (6) and to obtain at least one cardiac activity indicator (CI) from same.

Abstract: The systems and methods can provide continuous, efficient, accurate, non-contact, monitoring of one or more cardiorespiratory and/or behavior parameters associated with a subject in a defined environment using at least non-contact sensor data and provide feedback based on the determined parameters. The system can include one or more sensor modules disposed within defined environment(s). The system may further include one or more sensors disposed at a specific spatial location in the defined environment. The sensor(s) may include non-contact electric field sensor(s) configured to record non-contact sensor data related to one or more periods of stillness and/or movement of the subject. The system may further include one or more processors configured to determine cardiorespiratory respiratory parameters and/or behavior parameters using the non-contact sensor data.

Abstract: The disclosure is directed to a method and apparatus for measuring and assessing limb movement properties. The method includes conducting a test protocol with a position, velocity, and resistance meter (PVRM); and obtaining raw data from the PVRM and transmitting the raw data from the PVRM to an electronic device. The method includes processing the raw data to obtain processed data; and obtaining a set of parameters based on the processed data. The method includes obtaining a classification result according to a classifying algorithm based on the set of parameters; and assessing, recording, and displaying a limb movement property according to the classification result.

Abstract: Monitoring patients utilizing computer vision to analyze patient movements on or near a patient support apparatus such as a bed. Computer vision is employed to analyze video feed of patients to detect movements indicative of clinical parameters. Information generated by the computer vision processor can be recorded to a patient's electronic medical record. Such information can be used to make clinical assessments, diagnoses, or detect critical patient events requiring attention of caregivers. In instances where caregiver assistance is required, an alert can be communicated to one or more caregivers through a caregiver call system.

Abstract: A computer system configured to implement a method for real-time fitness tracking and scheduling is described herein. The computer system receives health data, a first health goal for completion during a first time period, and a second health goal for completion during a second time period for a user. A health profile is generated that includes the health data, the first health goal, and the second health goal. The health data is implemented in if-then scenarios to determine a first wellness action for the user to complete during a first time period to achieve the first health goal and a second wellness action for the user to complete during a second time period to achieve the second health goal. A health and wellness program is created for the user based on the first wellness action and the second wellness action.

Abstract: A strength assessment generator includes at least one sensor configured to detect movement data and a processor configured to generate a strength assessment based on the movement data detected by the at least one sensor. The at least one sensor is coupled to a body part of a person, and the movement data corresponds to movement of the body part when an object is moved by the body part.

Abstract: A disposable biosensor that includes a sensing surface having at least a working electrode portion and a reference electrode portion, a first reagent disposed on the working electrode portion containing a NAD(P)-dependent dehydrogenase, NAD(P)+, diaphorase, and an oxidized form of a redox mediator forming a working electrode, and a reference electrode material disposed on the reference electrode portion forming a reference electrode.

Abstract: Applicators for applying an on-skin assembly to skin of a host and methods of their use and/or manufacture are provided. An applicator includes an insertion assembly configured to insert at least a portion of the on-skin assembly into the skin of the host, a housing configured to house the insertion assembly, the housing comprising an aperture through which the on-skin assembly can pass, an actuation member configured to, upon activation, cause the insertion assembly to insert at least the portion of the on-skin assembly into the skin of the host, and a sealing element configured to provide a sterile barrier and a vapor barrier between an internal environment of the housing and an external environment of the housing.

Abstract: A method for monitoring glucose concentration in aqueous humor can include inserting an implantable device into an eye and determining glucose concentration as a function of glucose sensed at the implantable device. The method can optionally include optically detecting glucose concentration as a function of polarimetry and/or fluorescence. A system for monitoring glucose concentration can include devices described herein.

Abstract: Various embodiments of systems, devices and methods for detecting a sensor fault in an analyte sensor are disclosed. These embodiments utilize analyte metrics and thresholds.