Abstract: A sensor assembly may include a sensor surrounding a connector of a medical device. The sensor may be configured to detect a dimension of an end of another connector of another medical device when the another connector of the another medical device is connected to the connector of the medical device. A system may include the sensor assembly and one or more processors programmed and/or configured to determine a type of the another medical device based on the detected dimension. A method may include detecting, with a sensor surrounding a connector of a medical device, a dimension of an end of another connector of another medical device when the another connector of the another medical device is connected to the connector of the medical device; and determining a type of the another medical device based on the detected dimension.

Abstract: A device for connection to a medical connector, the device includes a cap body, a coupling cylinder adapted to engage with a male luer connector and a female luer connector, a bulb compartment filled with air, a reagent compartment filled with disinfectant or an antimicrobial reagent, and a passageway connecting the bulb compartment to the reagent compartment. The reagent compartment includes an exterior wall surface, an interior wall surface, an array of resealable pores densely integrated throughout the exterior wall surface and the interior wall surface of the reagent compartment, and a distal tip. The passageway may be positioned in an aperture of the proximal wall of the cap body. The coupling cylinder may include an O-ring.

Abstract: A needleless access connector having an access port and a sustained release antimicrobial coating only on a top surface of the access port is disclosed. The top surface of the access port can be defined by a top surface of a proximal end of a housing and a top surface of a head portion of a compressible valve disposed within an internal cavity of the housing. In certain embodiments of the present disclosure, the sustained release antimicrobial coating is on: (i) the top surface the proximal end of the housing, or (ii) the top surface of the head portion of the compressible valve, or (iii) the sustained release antimicrobial coating is only on both the top surface the proximal end of the housing and the top surface of the head portion of the compressible valve.

Abstract: A heart support device for circulatory assistance is disclosed. The device comprises a chamber body (10) defining a chamber having an internal volume configured to be filled with blood. The chamber body (10) has a first opening (12) and the chamber is dimensioned such that the first opening (12) and the chamber are fully disposed within a chamber of the human heart. A dynamic volume body (14) is provided and configured to be inflated or deflated to alternately increase or decrease the interior volume of the chamber. A catheter (16) comprising at least one lumen in fluid communication with the dynamic volume body is configured to deliver fluid to the dynamic volume body to inflate the dynamic volume body. A directional flow structure is configured to direct a flow of blood out of the chamber in a direction substantially aligned with a direction in which the catheter (16) extends.

Abstract: An example pump for driving a biological fluid is described herein. The pump can include an inner tubular structure and an outer tubular structure arranged around the inner tubular structure. The outer tubular structure can be configured as an artificial muscle. The pump can also include a gel layer disposed between the inner and outer tubular structures.

Abstract: Catheter blood pumps that include an expandable pump portion. The pump portions include a collapsible blood conduit that defines a blood lumen. The collapsible blood conduits include a collapsible scaffold adapted to provide radial support to the blood conduit. The pump portion also includes one or more impellers.

Abstract: Connectors and related methods for fluidly coupling a blood pump with an aorta facilitate implantation of the blood pump. A method of fluidly coupling a blood pump with an aorta includes positioning a connector device defining a passageway extending between a proximal opening and a distal opening. The connector device includes a support member surrounding the distal opening. The support member is interfaced with a wall of the aorta so that the distal opening is at a desired location of an inlet opening in the aorta. The support member is attached to the aorta around the distal opening so as to form a fluid seal and stabilize the connector device. A slit is incised in the wall of the aorta to form the inlet opening in the aorta. A proximal opening of the tubular connector is fluidly coupled with an outflow graft tube of the blood pump.

Abstract: A vascular coupling device for connecting an artificial heart pump to the vascular system of a subject is disclosed. The artificial heart pump may form part of a total artificial heart (TAH). The vascular coupling device comprises a first and a second coupling element, each one of said first and second coupling elements has a first end comprising a resilient coupling portion, a second end comprising a vascular grafting material, and a tubular midsection is arranged between said first and second ends. The vascular coupling device further comprises a coupling plate comprising a first receptor and a second receptor configured and adapted for receiving said resilient coupling portions of the first and second coupling elements.

Abstract: A wearable neurostimulation device is provided for providing transcutaneous peripheral nerve stimulation to a user. The neurostimulation device may include an enclosure housing the electronics for generating electric neurostimulation signals and an adjustable band detachably coupled to the enclosure. The enclosure may include a stimulation button and one or more auxiliary buttons. The band may be configured to be worn by a user, such as around the user's wrist or arm. The band may include locking tab which prevents the loop from being opened. The band may comprise electrodes positioned to stimulate the user's radial and median nerves. Also provided is a charger for holding and charging the neurostimulation device. The band may include an RFID tag that wireless communicates with an RFID antenna in the charger. The charger may not charge the neurostimulation device if the band is determined to be beyond a threshold age.

Abstract: A wearable electronic therapeutic device has one or more biometric detectors each for detecting one or more biometric parameters. The biometric parameters are dependent on at least one physiological change to a patient in response to a therapeutic treatment. A microprocessor receives the one or more biometric parameters and applies probabilistic analysis to determine if at least one physiological change threshold has been exceeded dependent on the probabilistic analysis of the two or more biometric parameters. An activation circuit activates an action depending on the determined exceeded physiological change. The action that is activated can be applying an elcetroceutical treatment in addition or as an alternative to a pharmaceutical treatment.

Abstract: A headset for use in delivering electrical stimulation to the skin surface of the head or in sensing one or more body parameters of the head of a user.

Abstract: A method of electrically stimulating a target muscle of a patient includes placing an array of stimulation electrodes in electrical contact with the target muscle, applying an electrical stimulation signal to the array of stimulation electrodes, obtaining a signal from a sensing element placed on the patient, wherein the signal characterizes at least one biological parameter associated with contraction of the target muscle, and determining which stimulation electrodes optimize the efficacy of the electrical stimulation signal based on measurements from the stimulation electrodes and the sensing element.

Abstract: An elongate stimulation assembly of an implantable stimulation device, including an intra-cochlear portion including an array of electrodes, and an extra-cochlear portion extending from the intra-cochlear portion, wherein the extra-cochlear portion includes a plurality of electrical lead wires in electrical communication with the array of electrodes and a malleable component extending in an elongate manner such that the malleable component is located further away from a longitudinal axis of the extra-cochlear portion than at least one of the electrical leads of the plurality of electrical leads.

Abstract: According to one embodiment a visual prosthesis is provided that includes an integrated circuit having a plurality of pixels and an array of electrodes connected to the pixels and configured to excite neurons in a retina. The prosthesis also includes one or more photovoltaic cells and a photodetector. The integrated circuit is configured to process signals from the photodetector to selectively activate the pixels. The present disclosure further relates to artificial vision systems including such prostheses and methods for inserting the prostheses.

Abstract: A method for assisting respiration by electrical stimulation includes: acquiring a time parameter of a target respiratory process; and outputting a phrenic nerve stimulating signal to a diaphragm stimulating electrode within a time period corresponding to inspiration and outputting an abdominal muscle stimulating signal to an abdominal muscle stimulating electrode within a time period corresponding to expiration, according to the time parameter of the target respiratory process.

Abstract: An implantable system, and methodology, for improving a heart's hemodynamic performance featuring (a) bimodal electrodes placeable on the diaphragm, out of contact with the heart, possessing one mode for sensing cardiac electrical activity, and another for applying cardiac-cycle-synchronized, asymptomatic electrical stimulation to the diaphragm to trigger biphasic, diaphragmatic motion, (b) an accelerometer adjacent the electrodes for sensing both heart sounds, and stimulation-induced diaphragmatic motion, and (c) circuit structure, connected both to the electrodes and the accelerometer, operable, in predetermined timed relationships to the presences of valid V-events noted in one of sensed electrical and sensed mechanical, cardiac activity, to deliver diaphragmatic stimulation.

Abstract: A system and method for extracting ETI load parametric data relative to one or more electrodes of an implanted stimulation lead system associated with an IPG. A Kelvin connection scheme is provided for measuring induced voltages present at stimulated electrodes during a stimulation ramping sequence, which may be used for determining the ETI parametric data using a number of techniques, including, without limitation, a waveform analysis.

Abstract: An automated neuromodulation system which uses patient feedback during a training phase in combination with machine learning to automatically provide optimal nerve stimulation parameters based on the patient's needs without patient input. The automated neuromodulation system generally includes a lead which is implanted in a patient for treatment of a wide range of conditions, such as chronic pain. The patient is provided with a remote control through which the patient may provide either positive or negative feedback relating to how the patient is responding to electrical stimulation in different situations. A control unit monitors feedback from the patient as well as information and data from the time of feedback, such as the patient's position, orientation, speed of movement, or other considerations. Using machine learning, the control unit may process the feedback and data to formulate an optimized neuromodulation protocol and criteria which may be automatically applied to the patient.

Abstract: Apparatus and methods are described for increasing sensitivity of sensory nerves of a portion of a subject's body. A plurality of electrodes (22) are placed at respective locations upon a surface of the body portion. A computer processor (24) applies sets of electrical stimulation pulses to the respective locations upon the surface, via the electrodes. The computer processor receives respective inputs from the subject, via a user interface (26), each of the inputs corresponding to a respective one of the sets of electrical stimulation pulses, and being indicative of a location at which the subject sensed the set of electrical stimulation pulse as having been applied. In response to the inputs from the subject, the computer processor modulates parameters of the sets of electrical stimulation pulses that are applied to respective locations upon the surface of the body portion. Other applications are also described.

Abstract: This document relates to methods and materials for providing stimulation or ablation to the stellate ganglion. For example, this document relates to methods and devices for providing stimulation or ablation to the stellate ganglion to modify blood pressure.

Abstract: Methods and apparatuses for collecting and quantifying patient-reported data from a neuromodulator. The patient-reported data typically includes a pain score that quantifies the level of pain experienced by the patient at a particular time. The apparatus can include a user interface that allows the patient to enter such information in real time. The methods and apparatuses can include a correlation process, whereby each patient-reported entry is correlated with a corresponding neuromodulation treatment. This correlation can be used to identify treatment parameters and dosages that are most effective, and to further identify when certain dosages are most effective. This information can further be used as feedback to generate optimized treatments for a specific patient and iteratively improve the treatments. In some cases, the correlation process identifies under reported or over reported data, which can be filtered out to provide more accurate optimized treatments.

Abstract: An interface unit for epicardial pacemaking and telemetry monitoring connects a pacemaker and bedside monitor for simultaneous pacing during electrogram visualization using epicardial pacing leads. The interface unit provides an electrically insulating housing having single handed manual attachment of the epicardial leads and a retractable protective shroud extending over the epicardial leads. The interface unit further provides electrical connectors for selective attachment to the pacemaker and bedside monitor.

Abstract: Solder reflowing a feedthrough pin to internal electronics of an electronic device and interface block constructions conducive to solder reflow.

Abstract: A primates herpes zoster treatment apparatus according to an embodiment of the present invention includes: a multiplication voltage generator multiplying a designated voltage into voltages with different high frequencies; a first treatment stimulation coil unit treating herpes zoster by outputting a magnetic stimulation pulse by the multiplied voltage with a first frequency; a second treatment stimulation coil unit treating a herpes zoster post-pain by outputting a magnetic stimulation pulse by the multiplied voltage with a second frequency; and a controller selectively driving the first treatment stimulation coil unit and the second treatment stimulation coil unit.

Abstract: A primates dementia treatment apparatus according to an embodiment of the present invention includes: a sensing unit including sensors that sense a cerebral state and a nerve conduction state of a cerebral cortex; a stimulation pulse output unit outputting a stimulation treatment pulse suitable for a cerebral cortex varied by a disease; and a controller controlling the stimulation pulse output unit to generate and output a stimulation treatment pulse customized for each user to be suitable for a form of a cerebral cortex varied by a disease in accordance with a result of real-time checking the cerebral state on the basis of sensing data of the sensing unit.

Abstract: A primates depression treatment apparatus according to an embodiment of the present invention include: a magnetic stimulation coil unit outputting magnetic stimulation having different characteristics corresponding to an asymmetry degree of a brain; and a controller determining an asymmetry degree between a left hemisphere and a right hemisphere on the basis of brain wave measurement data of the brain, and controlling the magnetic stimulation coil unit to output the magnetic stimulation having difference characteristics on the basis of control data that are determined in accordance with the determination result.

Abstract: An animal musculoskeletal treatment apparatus according to an embodiment of the present invention includes: a stimulation coil unit outputting a magnetic stimulation pulse as a treatment pulse for a predetermined lesion; a stimulation pulse driving unit generating and providing, to the stimulation coil unit, treatment pulses with different frequencies according to a type of a lesion; and a controller controlling the stimulation pulse driving unit such that the generated treatment pulses with different frequencies are selectively output to the stimulation coil unit.

Abstract: A magnetic stimulation device includes: a U-shaped magnetic core including a core body and a pair of legs extending in the same direction from the core body; conductors including a conductor having conductive layers that are wound around the leg and stacked in different levels and a conductor having conductive layers that are wound around the leg and stacked in different levels. The conductive layers are each formed of a wire having a rectangular cross section that is parallel to the longitudinal direction of the legs, and are connected in parallel to the respective legs. Between the legs, the wires of the conductive layers around the leg are respectively connected, at each level, to the wires of the conductive layers around the second leg.

Abstract: A device for delivering low-level electromagnetic radiation to a patient is provided herein. The device includes a support including a base surface that is substantially planar and configured to rest on a substrate. The support includes a contact surface opposite the base surface and contoured to support a curvature of a sub-occipital region and a lower neck region of the patient in a supine position, such that an upper portion of the head of the patient is cantilevered beyond the support. The device also includes a first plurality of emitters coupled to the support proximate to the contact surface and configured to emit low-level electromagnetic radiation transdermally to at least one of the sub-occipital region and the lower neck region.

Abstract: Aspects of the present disclosure are directed to, for example, a method of changing operational parameters of a laser probe. The method including the steps of recognising a connection pattern between the laser probe and a battery, setting the laser probe in a programmable mode, and receiving instructions for changing the operational parameters of the laser probe.

Abstract: Methods are disclosed for reduction of muscle fatigue, enhancement of wound healing and tissue repair and/or reduction of pain. The methods comprise irradiating a muscle or an injured tissue of a subject, as applicable, with pulsed blue and/or red light having an average irradiance that ranges from 0.1 mW/cm2 to 20 mW/cm2 at a radiant exposure that ranges from 0.5 J/cm2 to 60 J/cm2. The pulsed blue and/or red light is preferably applied with a flexible light source that includes a flexible light emitter positioned between a flexible anode and a flexible cathode. The flexible light emitter may comprise a printed LED film or OLEDs that emit blue and/or red light, or a printed LED film or OLEDs that emit blue light in combination with a quantum dot film that converts a portion of the blue light emission into red light.

Abstract: A method for applying cannabidiol onto and into the skin is provided. The method includes applying cannabidiol onto skin and irradiating the skin and the cannabidiol with a laser light. The laser light has a wavelength ranging from 800 nm to 870 nm. The irradiating of the skin with the laser light results in at least some of the cannabidiol penetrating into the skin. The cannabidiol can be provided in a kit with a laser emitting tool.

Abstract: A Seasonal Affective Disorder (SAD) treatment system providing seasonally appropriate and aesthetically appealing light therapy in a novel, convenient and medically effective manner. At present, patient compliance has proven to be a significant barrier to the effective treatment of this disorder. Studies have shown that up to 70% of patients report diminished compliance with the therapeutic recommendations using currently available forms of light therapy, in the form of “light boxes”. These patients sited the predominant factor in their failure to comply as shortcomings with the light boxes themselves, finding them “inconvenient” to set up and sit close to for therapeutic periods, or simply too aesthetically “displeasing” to keep in the home or workplace. As a result, as many as 20% of SAD patients who begin light box therapy stop their proscribed SAD lightbox therapy treatment prematurely and entirely.

Abstract: The invention relates to a mouthpiece and method for antibacterial treatment of intraoral surfaces. The mouthpiece comprises a body made of light-guiding material, the body comprising facial and lingual outer surfaces and facial and lingual inner surfaces adapted to face facial and lingual surfaces of teeth, respectively. A light source is attached to the body and adapted to deliver light to surfaces of teeth, the light source being positioned on at least one of said outer surfaces and adapted to deliver said light via said inner surfaces to both the facial and lingual surfaces of the teeth, wherein a portion of light is adapted to travel through said body from the facial side to the lingual side, or vice versa.

Abstract: A portable device for the decontamination of a breast. The aim of the device is to reduce the risk of mastitis, even when the patient has a medicament incompatibility. For this purpose, the invention includes a decontamination unit which decontaminates the breast at least by means of a physical method.

Abstract: A device for delivering low-level electromagnetic radiation to a patient includes a core portion including an upper surface and defining at least a portion of a base surface opposite the upper surface. The base surface is substantially planar and configured to rest on a substrate. The device also includes a cushion layer mounted on the upper surface and substantially defining a contact surface. The contact surface is opposite the base surface and contoured to support a curvature of a sub-occipital region and a lower neck region of the patient in a supine position. The device further includes a plurality of emitters coupled proximate to the contact surface and configured to emit low-level electromagnetic radiation transdermally to at least one of the sub-occipital region and the lower neck region.

Abstract: A brachytherapy treatment planning system includes a processor that: receives a planning image corresponding to at least a portion of a prostate; generates a brachytherapy treatment plan comprising, for each of a plurality of brachytherapy seeds or catheters, a corresponding brachytherapy seed or catheter position in the planning image such that the plurality of brachytherapy seed or catheter positions in the planning image together satisfy a desired radioactive dose objective in the prostate; receives a pre-treatment image corresponding to the at least a portion of a prostate; and maps each brachytherapy seed or catheter position in the planning image to a corresponding position in the pre-treatment image by performing a registration between the planning image and the pre-treatment image.

Abstract: Automatic radiation therapy treatment planning for generating a plan to be delivered from at least one beam angle, using a collimator having a variable collimator angle. Delivery times are determined for a number of possible collimator angles, and the optimization problem is defined to take the delivery times into account when selecting the collimator angles to be used when delivering the radiation.

Abstract: Methods and systems for radiation treatment planning and delivery apply a CODA cube. Cost values in the CODA cube may be used in the optimization of couch, collimator, and gantry angles simultaneously. Trajectories generated using the CODA cube show significant benefits when compared to conventional VMAT. A statistically significant sparing to OAR maximum radiation doses was seen. CODA plans resulted in a reduction to maximum radiation dose in OARs of 20.6% (p<0.01), with maximum brainstem radiation dose decreased by 2.63 Gy (p=0.031) on average. Mean reduction in total MU was 8.6% (p=0.156), and a mean decrease in non-target brain tissue receiving 12 Gy or higher was 3.9% (p=0.16), when compared to standard VMAT methods (n=7).

Abstract: Systems and methods are disclosed for generating radiotherapy treatment machine parameters based on projection images of a target anatomy. The systems and methods include operations including receiving a set of pairs of image data for each gantry angle of a radiotherapy treatment machine, wherein each pair of the set of pairs comprises a given projection image that represents a view of an anatomy of a subject from a given gantry angle and a given graphical aperture image of multi-leaf collimator (MLC) leaf positions at the given gantry angle based on the given projection image; training a generative adversarial network (GAN) model based on the set of pairs of image data for each gantry angle; and using the trained GAN model to predict an aperture image of MLC leaf positions for a desired gantry angle based on a projection image that represents a view of an anatomical region of interest.

Abstract: The present disclosure relates to a device capable of removing senescent cells by facilitating the phagocytosis of the senescent cells by specifically stimulating the senescent cells using an ultrasound output unit, a kit for removing senescent cells and a method for specifically removing senescent cells, and by selectively and specifically stimulating senescent cells by irradiating ultrasound under a specific condition, thereby promoting the secretion of various cytokines recruiting immune cells, only the senescent cells can be removed specifically and, furthermore, cell regeneration can be promoted.

Abstract: The present invention relates to a tool, comprising at least one motor. Further comprising a pump connected to the motor, a work cylinder in fluid connection with the pump and an actuable tool component connected to the work cylinder, characterised in that the pump and the motor are arranged directly adjacent on a common singular motor and pump shaft, without any intervening coupling, transmission or the like. Furthermore, the invention relates to an assembly of a motor and a pump on a common shaft.

Abstract: A vehicle door glass breaking device includes a breaking portion including a pointed end portion configured to point towards an inner surface of a door glass; a guide portion configured to be disposed at the inner surface of the door glass, and guiding the breaking portion in a thickness direction of the door glass; and a restricting portion configured, in a case in which a pressing force, applied by a vehicle occupant to another end portion of the breaking portion, at an opposite side of the breaking portion from the pointed end portion, in a direction towards a side of the door glass, is equal to or greater than a predetermined magnitude, to permit displacement of the breaking portion towards the door glass, and in a case in which the pressing force is smaller than the predetermined magnitude, to restrict displacement of the breaking portion towards the door glass.

Abstract: A disclosed breathing hose is configured to duct inhaled and exhaled gas between a user and a rebreather apparatus. The breathing hose includes a non-collapsible flexible outer tube and a collapsible inner tube located within the non-collapsible flexible outer tube. The collapsible inner tube is configured to inflate to accommodate the exhaled gas of the user and to deflate to accommodate the inhaled gas of the user. The collapsible inner tube has a size that accommodates at least a portion of a breath volume of the user and may have a size that is configured to accommodate a maximum breath volume of the user. The collapsible inner tube is configured to act to maintain a constant total volume of gas in the lungs of the user and in the rebreather unit throughout a breathing cycle. The breathing hose may be part of a closed-circuit or semi closed-circuit rebreather apparatus.

Abstract: A respirator including a facepiece with a transparent lens that is recessed radially-inwardly relative to an opaque frame of an opaque chassis of the facepiece. The respirator is configured to receive a vision-protecting module.

Abstract: Among others, the present invention provides masks each with mask filter or mask body comprising one or more filter layers fabricated by integrated circuit fabrication processes. Such filter layer includes well-defined and substantially uniform pore size, and allows the mask to be washable and reusable. The prevention invention also provides methods for fabricating a single layer or multi-layer mask body or mask filter to be incorporated by a face mask.

Abstract: A system for fire suppression having a fuel tank inerting system configured to produce an inert gas mixture, a water source, and a low pressure misting nozzle directed into a cargo hold. The low pressure misting nozzle is configured to produce a mist solution using the inert gas mixture and water.

Abstract: Systems and methods are disclosed for fire suppression. One method of fire suppression may include sensing initial environmental parameters in an area of interest, and determining whether or not to enable the fire suppression system, based at least in part on the sensed initial parameters. Then subsequently sensing subsequent environmental parameters, and determining whether to enable or disable the fire suppression system, based at least in part on the sensed subsequent environmental parameters.

Abstract: Multiple robotic monitors are located in a hydrocarbon storage or transport facility. Each robotic monitor is communicably coupled to other robotic monitors and includes a heat sensor configured to detect heat emitted by a hydrocarbon tank of the hydrocarbon storage or transport facility. A controller is communicably coupled to the heat sensor and configured to generate a heat signature based on the heat detected by the heat sensor. A pump is communicably coupled to the controller and configured to exert pressure on a fire retardant, responsive to the generation of the heat signature by the controller. An outlet is mechanically coupled to the pump and configured to discharge the fire retardant at the hydrocarbon tank.

Abstract: To suppress the influence of gas on other fuel tanks when the gas is discharged from a fuel tank. A fuel storage device includes: a plurality of fuel tanks, each having a fusible plug valve; a support member that supports the plurality of fuel tanks, while making longitudinal directions of the respective fuel tanks parallel to each other; and a blocking member that blocks at least part of the fuel gas discharged from the fusible plug valves. The plurality of fuel tanks includes a tank group including the plurality of fuel tanks aligned along a first direction and a juxtaposed tank thereto. The blocking member is disposed between the tank group and the juxtaposed tank. The orientations of openings of the fusible plug valves included in blocked tanks are directed toward the blocking member, the blocked tanks being two or more fuel tanks that are continuous in the first direction, among the fuel tanks included in the tank group.