Abstract: An apparatus and method for determining bio-information of a target using an impulse radar are provided. The method may include generating a frame set by accumulating frames received at preset time intervals, determining a first magnitude spectrum of the frame set corresponding to a first frequency axis by performing a frequency conversion of frames included in the frame set in a sampler index axis direction, determining a second magnitude spectrum of the frame set corresponding to the first frequency axis and a second frequency axis by performing a frequency conversion of the first magnitude spectrum in a time axis direction, determining a third magnitude spectrum of the frame set by adding up values of the second magnitude spectrum for each second frequency, and determining a frequency indicating a peak in the third magnitude spectrum as a heartbeat frequency of the target.

Abstract: Systems and methods have been developed for implementation of a portable SIBO testing system for convenient sampling of intestinal gases exhaled from a patient's breath. These devices may be in the form of a hand held meter that would integrate with a smartphone or other device with an application that can record data relating to food consumed by a user. Various technologies may be utilized to measure the levels of gases exhaled by a user, which may include (1) sorbent based technology and (2) membrane based technology. In some examples, the system will determine an indication of whether a patient has SIBO by adjusting a change in exhaled hydrogen concentration by a methane level exhaled by a patient.

Abstract: The disclosure relates to a method for providing original data that can be used for subsequently determining the function of an organ of a living organism or for subsequently diagnosing a disease or a severity of a disease of an organ of a living organism. This method is characterized by several steps, one of which is administering a marker substance to a living organism by inhalation, wherein the marker substance has a vapor pressure above 0.01 mmHg at 37° C. In other method steps, the concentration of this marker substance in exhaled air is determined at at least two different time points. Then, a difference in marker substance concentration is calculated.

Abstract: A method of detecting hypoxia. Detecting hypoxia includes detecting, in exhaled breath, at least one indicator for hypoxia. The at least one indicator is selected from the group consisting of pentanal, 2-pentanone, 2-hexanone, 2-heptanone, 2-cyclopenten-1-one, and 4-butyrolactone.

Abstract: A method includes generating, via a camera, image data that is reproducible as an image of at least a portion of a subject. The method also includes receiving, via a sensor, first biomeasurement data associated with the subject, the first biomeasurement data including a first biomeasurement of the subject. The method also includes verifying the first biomeasurement of the subject based at least in part on a comparison between at least a portion of the image data and at least a portion of the first biomeasurement data.

Abstract: Electronic devices for displaying user interfaces and, more specifically, for displaying user interfaces associated with physical activities are described. In some embodiments, the user interfaces are associated with configuring a pace alert for a workout application.

Abstract: In accordance with an example embodiment a method, apparatus and computer program product are provided. The method comprises receiving, at an apparatus, a sampled data associated with an activity from one or more sensors wirelessly coupled to the apparatus. The sampled data is generated at the one or more sensors based on a compressive sampling of an activity data associated with the activity. The compressive sampling is performed based on a sampling information. The activity is classified based at least on the sampled data. An error associated with the classification of the activity is determined. The sampling information is updated or retained based on a comparison of the error with a threshold error. The updated sampling information is utilized for generating an updated sampled data. The updated sampled data facilitates in reclassification of the activity.

Abstract: A disposable lancet assembly includes: a spring aligned along a linear axis; a lancet aligned along the linear axis adjacent to the spring; a needle cup aligned along the linear axis adjacent to the lancet; and a housing including a channel that accepts an actuator interface such that the needle cup and lancet are able to be moved along the linear axis via the actuator interface. A medical test cartridge includes: a bottom plate; a microfluidic chip; and a top plate, wherein the top plate is coupled to the bottom plate such that the microfluidic chip is retained between the top plate and the bottom plate. A sample collection and testing device includes: a lancet assembly; a lancet actuator coupled to the lancet assembly; and a microfluidic test chip.

Abstract: Methods and systems for sensor calibration and sensor glucose (SG) fusion are used advantageously to improve the accuracy and reliability of orthogonally redundant glucose sensor devices, which may include optical and electrochemical glucose sensors. Calibration for both sensors may be achieved via fixed-offset and/or dynamic regression methodologies, depending, e.g., on sensor stability and Isig-Ratio pair correlation. For SG fusion, respective integrity checks may be performed for SG values from the optical and electrochemical sensors, and the SG values calibrated if the integrity checks are passed. Integrity checks may include checking for sensitivity loss, noise, and drift. If the integrity checks are failed, in-line sensor mapping between the electrochemical and optical sensors may be performed prior to calibration.

Abstract: An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte.

Abstract: A sensor system (110), a method of manufacturing a flexible electronics patch (114) for use in a sensor system (110) and a method of manufacturing a sensor system (110). The sensor system (110) comprises—at least one analyte sensor (112) configured for at least partial implementation into a body tissue of a user; —at least one flexible electronics patch (114), the flexible electronics patch (114) comprising—at least one applicator unit (134) for applying the flexible electronics patch (114) to the skin (132) of the user; and —at least one second adhesive layer (136) for adhering the flexible electronics patch (114) to the applicator unit (134) before applying the flexible electronics patch (114) to the skin (132) of the user.

Abstract: Presented are systems and methods that perform noninvasive glucose monitoring using mid-infrared self-emission of the human body that acts as a background radiation emitter. Various embodiments accomplish this by taking advantage of the guided-mode resonance (GMR) effect in a number of bandpass filters that are constructed as an array of coplanar filters. The filter array acts as a spectral separator that uses a grating layer and a thin film waveguide to form reflection and transmission filters for particular wavelengths. Unlike, common multi-layer optical filter designs that utilize numerous individual optical filters, a novel GMR filter design comprises an array of filters that may be fabricated from CMOS-compatible materials using only a few thin film and grating layers to filter light. Advantageously, this reduces manufacturing cost and allows for simultaneous monitoring of a number of wavelengths of the glucose spectrum.

Abstract: Systems and methods for measuring electrophysiological and electrochemical signals in a portion of a body of a subject are provided. The structure includes an array of electrochemical sensors made of miniaturized multi-layer graphene, an array of electrophysiological electrodes, an integrated front-end readout circuit, and narrow silicon shafts with metal spines. The sensor arrays offer significantly higher sensitivity than conventional methods and enable simultaneous, multi-site measurement of chemical and electrophysiological. The front-end circuit contains features that allow significant improvement in detection of the resulting electrochemical current produced by the electrochemical sensing electrodes. The silicone probes allow measurements deep in the body.

Abstract: A blood sampler device includes a sampler body forming a hollow internal chamber with upper and lower openings, the sampler body including a sealing device disposed adjacent to the upper opening. The blood sampler device further includes a blood collector adapted to be inserted into the sampler body, the blood collector including a plurality of capillary channels.

Abstract: A safety needle device includes a housing including a passageway with a needle cannula extending therefrom. A shielding member is movable between a first position in which a puncture tip of the needle cannula is exposed therefrom and a second position in which the puncture tip of the needle cannula is encompassed therein. The shielding member is maintained in the first position against a biasing force which biases the shielding member toward the second position. A fluid and/or a temperature activation material is associated with the shielding member and is adapted to deform upon contact with a fluid medium and/or a certain temperature or temperature range. The fluid medium flowing through the needle cannula causes the fluid activation material to deform, such as through expansion, thereby releasing the shielding member from the first position and allowing a drive member to bias the shielding member toward the second position.

Abstract: A system includes a display device, a user interface, a memory, and a control system. The memory contains machine readable medium including machine executable code storing instructions for performing a method. The control system is coupled to the memory, and includes one or more processors. The control system is configured to execute the machine executable code to cause the control system to display, on the display device, a series of questions from mental health questionnaires. The series of questions includes text and answers for each question. From the user interface, a selection of answers of each of the displayed series of questions is received from a patient. Using a Bayesian Decision List, the received selection of answers is processed to output an indication of mental health of the patient. The indication of mental health identifies a kappa opioid receptor antagonist to which the patient would likely be a higher responder.

Abstract: Devices and methods provide for the sensing of physiological signals during stimulation therapy by preventing stimulation waveform artifacts from being passed through to the amplification of the sensed physiological signal. Thus, the amplifiers are not adversely affected by the stimulation waveform and can provide for successful sensing of physiological signals between stimulation waveform pulses. A blanking switch may be used to blank the stimulation waveform artifacts where the blanking switch is operated in a manner synchronized with the stimulation waveform so that conduction in the sensing path is blocked during the stimulation pulse as well as during other troublesome artifacts such as a peak of a recharge pulse. A limiter may be used to limit the amplitude of the sensed signal, and hence the stimulation artifacts, that are passed to the amplifier without any synchronization of the limiter to the stimulation waveform.

Abstract: An electrocardiography patch is provided. A pair of electrodes are exposed on a contact surface of a flexible backing. A circuit includes a pair of circuit traces and each circuit trace is electrically coupled to one of the electrodes in the pair. A plurality of electrical pads are positioned between the electrodes and above at least a portion of the circuit traces. A pair of the electrical pads interface with the electrodes. A pair of battery leads electrically interface a battery to another pair of the electrical pads.

Abstract: Methods and systems for preparing electroanatomic maps of the heart operate using a probe that has been inserted into a heart chamber by emitting electrical calibration signals from external locations that are outside the subjects body, receiving the calibration signals in a plurality of intracardiac electrodes on the probe, and determining functional relationships between the emitted calibration signals and the received calibration signals. Thereafter, electrophysiological signals from respective origins in the heart are detected in the external locations, and the functional relationships are applied to the detected electrophysiological signals to calculate intracardiac potentials at the respective origins.

Abstract: Disclosed systems include mobile ECG sensors, systems and methods. Some embodiments provide ECG sensors in a credit card form factor that allows a user to contact two electrically isolated electrodes to measure heart electrical signals for a Lead 1 ECG.

Abstract: Apparatuses and methods for extracting, de-noising, and analyzing electrocardiogram signals. Any of the apparatuses described herein may be implemented as a (or as part of a) computerized system. For example, described herein are apparatuses and methods of using them or performing the methods, for extracting and/or de-noising ECG signals from a starting signal. Also described herein are apparatuses and methods for analyzing an ECG signal, for example, to generate one or more indicators or markers of cardiac fitness, including in particular indicators of atrial fibrillation. Described herein are apparatuses and method for determining if a patient is experiencing a cardiac event, such as an arrhythmia.

Abstract: QRS activity duration may be indicative of cardiac tissue health. Accordingly, maps of QRS activity duration may be beneficial to practitioners. To this end, an electroanatomical mapping system can receive an electrogram signal and analyze it by transforming it into the wavelet domain, computing an energy function of the resultant scalogram, and computing QRS activity duration using the energy function. A graphical representation of the QRS activity duration can be output, for example on a three-dimensional cardiac model. Areas of diseased substrate can be identified on the output; in some aspects of the disclosure, diseased substrate corresponds to areas where the QRS activity duration exceeds a preset threshold, such as about 70 ms.

Abstract: An access system has a scanner that scans a unique identifier to access a location. A display receives an input. An automated dispenser dispenses at least one scent on each hand of an individual responsive to a control signal. A processor controls access to the location. A memory stores a set of instructions that configures the processor to receive the unique identifier from the scanner, actuate the automated dispenser to dispense the at least one scent responsive to receipt of the unique identifier, receive the response input based on the scents detected by the individual of the at least one scent, determine a passing result or a failing result responsive to the received response input and an expected response based on the dispensed at least one scent, enable access to the location responsive to a passing result and deny access to the controlled access location responsive to a failing result.

Abstract: A swallowing sensor that is attached to a person's pharyngeal portion and that measures the person's swallowing ability includes: a film-shaped detector that detects vibration based on displacement and sound of the pharyngeal portion; an adhesive layer that is provided on one of two main sides of the detector and that attaches the detector to the pharyngeal portion; and a sensing film arranged on the detector to cover entirety of the other main side of the detector, wherein a main side of the sensing film that contacts the detector contains an adhesive component, the sensing film is attachable to the pharyngeal portion around the detector using the adhesive component, and the sensing film conveys vibration to the detector. Accordingly, the swallowing ability can be more accurately measured.

Abstract: An advice system employs a genetic analysis of a patient to identify one or more characteristics of the patient. The advice system employs the characteristics to identify one or more attributes of a medical device that would desirably exist in a medical device that is to be prescribed for the patient. The advice system then identifies from the one or more attributes one or more medical devices from among a plurality of medical devices whose features at least in part meet the one or more attributes. The advice system then outputs a recommendation of the one or more medical devices. The system employs known genes that are expressive of certain traits in a person, with the known traits being interpreted or evaluated in terms of characteristics that are relevant in selecting a medical device from among a plurality of medical devices, such as patient interface devices or other devices.

Abstract: A bio-information processing apparatus includes: an in vivo material measurer which measures an in vivo material of a user; and a processor which extracts a pattern of change of the in vivo material of the user based on a measurement result of the in vivo material, compares the extracted pattern of change of the in vivo material with a biological rhythm reference model, and determines whether biological rhythms of the user are disrupted based on a result of the comparison.

Abstract: A walking training system and walking training machine capable of remarkably enhancing the effect of improving an independent walking function are proposed. When a subject having a lower limb functional disorder performs walking training, the degree of dependency on upper limbs can be evaluated by enabling the subject to recognize transitional reductions of a load on a holding part(s) by feeding back the transitional reductions of the load as a sense to feel them.

Abstract: The present disclosure provides a method of assessing periorbital puffiness in a subject by determining if the subject exhibits pseudoherniation of one or more upper eyelid fat pads and/or one or more of the lower eyelid fat pads, determining if the subject exhibits one or more conditions selected from the group consisting of: edema of the fat pad, edema along the soft tissue of the upper and/or lower eyelids, malar mounds due to edema, malar edema, and mild festoons aggravated by edema, and scoring the periorbital puffiness from both determinations.

Abstract: The invention provided herein relates to a wearable medical device and methods of use thereof for monitoring brain signals by electroencephalography technology in critically ill subjects suspected of having abnormal brain wave patterns including but not limited to electrographic seizures, spike and waves, periodic discharges and rhythmic delta activity.

Abstract: A semiconductor device includes an antenna mounted on a wiring substrate. A holding member includes a first plate-shaped part having a first surface and a second surface, a second plate-shaped part having a third surface and a fourth surface, and a coupling part configured to couple the first plate-shaped part and the second plate-shaped part so that the second surface and the third surface have parts facing each other with a space therebetween. The one end of the wiring substrate is fixed to the holding member so that the antenna overlaps the coupling part, as seen from above. A part continuing to the one end of the wiring substrate is folded back so as to being arranged sequentially along the first surface, the second surface, the third surface, and the fourth surface. The other end of the wiring substrate extends in an elastically deformable state from the fourth surface.

Abstract: An implantable medical device system includes a pacemaker and an implantable cardioverter defibrillator (ICD). The pacemaker is configured to confirm a hemodynamically unstable rhythm based on an activity metric determined from an activity sensor signal after detecting a ventricular tachyarrhythmia and withhold anti-tachycardia pacing (ATP) pulses in response to confirming the hemodynamically unstable rhythm. The pacemaker may deliver ATP when a hemodynamically unstable rhythm is not confirmed based on the activity metric. The ICD is configured to detect the ATP and withhold a shock therapy in response to detecting the ATP in some examples.

Abstract: Embodiments provide devices, systems and methods for measuring a gastric emptying (GE) parameter (GEP). Many embodiments provide a swallowable capsule having three electrodes one covered by a coating which remains in the stomach but is degraded in the small intestine (SI). The electrodes are coupled to circuitry such that when the capsule is in the stomach, current flow occurs between the first two electrodes generating a first signal and in the SI current flow occurs between the second and now uncovered third electrode generating a second signal. These two signals can be transmitted and analyzed externally or by an internal controller to determine a GEP e.g., GE time. The patient may wear an external device configured to receive and analyze the signals to determine GE time. Embodiments of the invention may be used to diagnose gastroparesis and provide patient's information on when to eat meals or administer insulin after eating.

Abstract: Apparatus and methods related to an underbody support for supporting a body of a being, such as during surgery to prevent contact pressure injuries. In certain embodiments, the underbody support may include one or more inflatable chambers enclosing a volume. At least one of the inflatable chambers may include one or more compression sensitive switches for monitoring the volume of the inflatable chamber, and the one or more compression sensitive switches may be located within the inflatable chamber. In some embodiments the one or more compression sensitive switches are sized to close when the said inflatable chamber is deflated to a desired residual volume.

Abstract: This document discusses, among other things, systems and methods to produce a combined heart sound signal of a patient using a first signal including heart sound information over a first physiologic interval and a second signal including heart sound information over the first physiologic interval.

Abstract: Circuits are provided for detecting an electrosurgical unit signal. An example circuit includes: a filter configured to process a floating ground signal associated with measuring a bio potential signal of a patient, and a detector configured to output a sensing signal based at least in part on the floating grounding and the Earth ground for detecting an electrosurgical unit signal.

Abstract: In various embodiments, a first classification assigned to a periodic component of an electrical waveform that represents electrical activity in a patient's heart may be identified (302). A corresponding periodic component of a hemodynamic waveform that represents hemodynamic activity in the patient's cardiovascular system may be analyzed (306, 318, 328). The corresponding periodic component may be causally related to the periodic component of the electrical waveform. Based on the analysis, the previously-assigned classification may be assigned (312, 324) to the corresponding periodic component of the hemodynamic waveform in response to a determination, based on the analyzing, that the previously-assigned classification also applies to the corresponding periodic component.

Abstract: An ECG signal lossless compression system includes: a signal difference value generating module and a compression module. The signal difference value generating module performs an adaptive linear prediction encoding on an ECG signal, so as to generate a plurality of signal difference values corresponding to each datum of the ECG signal; the compression module divides the signal difference values into a plurality of groups and performs an adaptive linear lossless compression encoding on each group, so as to generate a plurality of window compression streams, wherein each group corresponds to a bit reference index configured to be a compression encoding parameter of the adaptive linear lossless compression encoding.

Abstract: A method for detecting and predicting an epileptic seizure. The method includes preparing a plurality of electrical signals, extracting a plurality of patterns from the plurality of electrical signals, extracting a plurality of features from the plurality of electrical signals by applying the plurality of patterns on the plurality of electrical signals, optimizing the plurality of patterns and the plurality of features, and classifying each of the plurality of electrical signals in a plurality of classes by applying a plurality of classifiers on the plurality of features. The plurality of electrical signals include a plurality of samples. The plurality of classes include a seizure class and a non-seizure class, and the plurality of classifiers include a plurality of cascaded AdaBoost classifiers.

Abstract: Disclosed are systems for non-invasively determining a measurement of an analyte. The systems include an electrocardiogram sensor and a processing device operatively coupled to the electrocardiogram sensor. The processing device can execute instructions to receive electrocardiogram data from the electrocardiogram sensor and apply a machine learning model, wherein the machine learning model has been trained based on previous electrocardiogram data associated with a subject and source of an analyte measurement associated with the subject. The system may also determine an indication of a level of the analyte based on the electrocardiogram data.

Abstract: Disclosed is a wearable device comprising: an impedance sensor for measuring an impedance signal inside a user's body; and a controller for determining the number of meals for a predetermined period and the glycemic index corresponding to each meal using the measured impedance signal and providing the user's eating habit information on the basis of the number of meals and the glycemic index.

Abstract: A physical stability determination system includes a wearable device configured to collect sleep information, activity information and heartbeat information of a user, a data preprocessor configured to divide each of the activity information and the heartbeat information into data of a sleep area and data of an activity area, based on the sleep information, and a data processor configured to calculate a sleep state, an activity intensity or a heartbeat state of the user from the data of the sleep area and the data of the activity area. The data of the sleep area may be used to calculate the sleep state in the data processor, and the data of the activity area may be used to calculate the activity intensity or the heartbeat state in the data processor.

Abstract: A diagnosis support system having an image sensor that captures a medical image and a processor configured to capture medical images of which imaging times are different, store any of medical images as representative images, store the medical images excluding the representative images as groups of neighboring images such that each the groups of neighboring images are associated with the representative images, display the representative images in a list on a display device, receive a selection from the representative images displayed in the list, extract a neighboring image for diagnosis from among a group of neighboring images which is associated with a selected representative image, and display the extracted neighboring image for diagnosis on the display.

Abstract: A production method for test X-ray includes preparation (S10) of first CT data (B) of an inspection object, second CT data (BM) for metal portions of the inspection object, and third CT data (TM) for metal portions of a target object, transformation (S20) of the first, second, and third CT data (B, BM, TM) from the image space (BR) into corresponding first sinogram data (SB), second sinogram data (SBM), and third sinogram data (STM) in the radon space (RR), calculation (S30, S40) of the artifact sinogram data (SA), back-transformation (S50) of the artifact sinogram data (SA) from the radon space (RR) into the image space (BR) in CT artifact data (A) for the artifacts that are to be inserted, and insertion of the CT artifact data (A) into the first CT data (B).

Abstract: A method of conducting a multi-pass dynamic positron emission tomography (PET) scans using continuous bed motion (CBM) mode is disclosed where the method involves acquiring PET sinogram data using CBM mode as the patient bed is moving in a first direction; acquiring PET sonogram data using CBM mode as the patient bed is moving in a second direction that is opposite from the first direction; and reconstructing 3-D PET image from the acquired PET sonogram data.

Abstract: A system and method for providing image guidance for planning approach paths for one or more medical devices at a target location. The system can receive a volumetric medical image, determine a density of content within the volumetric medical image, receive an indication of a target location within the volumetric medical image, identify obstructing objects within the volumetric medical image, and determine a plurality of pathways from an approach region of the volumetric medical image to the target location. The system can cause a display to concurrently display the volumetric medical image and a plurality of emplacements for one or more medical imaging devices.

Abstract: An anti-scatter grid, a detector with such an anti-scatter grid and a radiation imaging system including such a detector with an anti-scatter grid are provided. The anti-scatter grid includes at least one grid wall. The parameters of the grid wall may be adjusted to arrive a uniform scatter-to-primary ratio. The parameters of the grid wall comprise thickness, height, shape, or position of the grid wall, or width of interspace between two grid walls. The detector includes the anti-scatter grid, at least one photosensor, and at least one scintillator. The radiation system includes a radiation generator, a radiation detector with the anti-scatter grid, and a processor.

Abstract: There is disclosed a mobile radiographic imaging apparatus including a component operable to emit radiation for imaging a subject, an arm rotatably connected at a proximal end thereof to a body section of the apparatus, such that it is supported by the body section and can slew relative to the body section about an upright axis, and to a distal end of which said component is connected, and a generator assembly arranged in the body section and including a generator arranged in the casing and electrically connected to said component, the apparatus being configured such that the generator assembly rotates with the arm, about said axis, wherein the generator assembly has a centre of mass which is radially offset from said axis in a second direction that is substantially opposite to said first direction.

Abstract: A mobile X-ray imaging apparatus includes a first column rotatably coupled to a main body and extending in one direction; a second column extending in the one direction and slidably coupled to the first column in an extension direction of the first column; a display provided in the main body; and a indicator arranged in one end of the second column.

Abstract: A medical X-ray system and a method perform radiological examinations of patients. In order to allow particularly efficient operation of the medial X-ray device, a data processing system of the X-ray system processes data processing processes in parallel and has multiple user interfaces that are used to provide a data input and/or data output option for respective different data processing processes at the same time.

Abstract: A method of operating a mobile fluoroscopic imaging system includes positioning an x-ray source and a DR detector about a patient. Data defining a spatial configuration of the x-ray source and the collimator is stored in the system. The system is configured to determine a source-to-image distance of the x-ray source and the DR detector including by activating the x-ray source and capturing a scout image in the DR detector. Dimensions of the scout image are calculated and the source-to-image distance is determined based on the data defining the spatial configuration of the x-ray source and the collimator and on the dimensions of the scout image.