Abstract: A surgical gas delivery device includes a filter cartridge interface and a computer controlled control unit configured to control the circulation of surgical gas during endoscopic surgery. The control unit can operate in a plurality of different modes of operation. A tube set for connecting the surgical gas delivery device to one or more end effectors includes a filter cartridge in fluid communication with the tube set. The filter cartridge is seated in the filter cartridge interface of the surgical gas delivery device to communicate surgical gas between the surgical gas delivery device and the one or more end effectors. The surgical gas delivery device includes a reader operatively connected to receive input from a data carrying element of the tube set. The data carrying element, reader, and control unit can launch a specific one of the modes of operation when the filter cartridge is inserted.

Abstract: An evacuation system for continuously removing gas from a body cavity of a patient during an endoscopic surgical procedure is disclosed, which includes an inlet flow path leading to a first trocar communicating with the body cavity through which an essentially continuous flow of gas is delivered to the body cavity, an outlet flow path leading from a second trocar communicating with the body cavity though which an essentially continuous flow of gas is removed from the body cavity, a pump communicating at least with the outlet flow path for removing an essentially continuous flow of gas from the surgical cavity, and a processor operatively associated with the pump for controlling at least the essentially continuous flow of gas from the body cavity.

Abstract: Dose delivery device with partially or fully surrounding cover may be removed to open fluid communication with a dose chamber. The cover may allow an inhaler to be stored in sterile or otherwise in a controlled environment prior to use, and removal of the cover may automatically prepare the inhaler for use.

Abstract: A protective cover for a nasal cannula completely encloses the two prongs of the nasal cannula when properly installed. This protective cover will keep the nasal cannula from contacting potentially unclean surfaces when the nasal cannula is not in use. An optional UV light may be present in the protective cover to provide UV cleaning of the nasal cannula prongs when the cover is closed.

Abstract: A ventilator that is small, lightweight, and portable, yet capable of being quickly adapted to operate in a plurality of different modes and configurations to deliver a variety of therapies to a patent. A porting system having a plurality of sensors structured to monitor a number of parameters with respect to the flow of gas, and a number of porting blocks is used to reconfigure the ventilator so that it operates as a single-limb or dual limb ventilator. In the single-limb configuration, an active or passive exhaust assembly can be provided proximate to the patient. The ventilator is capable of operate in a volume or pressure support mode, even in a single-limb configuration. In addition, a power control mechanism controls the supply of power to the ventilator from an AC power source, a lead acid battery, an internal rechargeable battery pack, and a detachable battery pack.

Abstract: The system described comprises a respiratory therapy flow device, a respiratory circuit, and an exhalation valve. The device includes an exhalation pressure control port. The exhalation valve is removably engaged with the exhalation pressure control port and the respiratory circuit. The valve comprises a lid, a diaphragm, and a housing body. The housing body comprises a ramped lock configured to engage the respiratory therapy flow device at the exhalation pressure control port. Responsive to an engagement between the valve and the exhalation pressure control port, the lid forms a compression seal with the exhalation pressure control port, the diaphragm forms a compression seal with the lid, and the diaphragm is selectively controlled via gas pressure received through the exhalation pressure control port such that gas in the respiratory circuit flows to the ambient atmosphere during exhalation by the subject.

Abstract: A gas washout vent, and a patient interface with the gas washout vent, configured to allow patient-exhaled CO2 to flow to an exterior of the plenum chamber to minimise rebreathing of exhaled CO2 by the patient, the gas washout vent including at least one outlet orifice; a diffusing member at least partly covering the outlet orifice; and a blocking member having an air-impermeable material, the blocking member preventing gas exiting from the outlet orifice from flowing straight through the diffusing member.

Abstract: A method for calming a crying of a baby using a computer system having a memory, a microprocessor, a voice and digital visual display, and a user interface, the method comprising: providing a recording of white noise to a media player or to the computer system, providing a sensor in communication with the microprocessor, wherein the sensor is configured for measuring muscle contractions of a baby, and instructing, in response to a predetermined number of muscle contractions of the baby, the recording of the white noise to be played into headphones on ears of the baby.

Abstract: A system comprises a flexible pad, an antenna wire disposed within the flexible pad, and an electronics unit connected to or capable of being connected to the antenna wire. The electronics unit can include circuitry configured to access a stored playlist representing a sequence of tones at different frequencies, and to generate signals representing the tones such that two or more of the tones are generated in the sequence according to the stored playlist. The electronics unit further can include an oscillator to generate a carrier signal and coupled so that the signals representing the tones modulate the carrier signal according to the sequence when applied to an input of the oscillator, where the oscillator has an output connected to transmit the modulated carrier signal onto an antenna when the electronics unit is in operation.

Abstract: A vehicle nightlight assembly for soothing a child in a vehicle includes a light emitting unit is positionable on a car seat for a child in a vehicle. The light emitting unit emits light at an intensity of no greater than 20.0 lumens. In this way the light emitting unit can soothe a child in the car seat while simultaneously avoiding negatively affecting night vision of a driver of the vehicle. A magnet is coupled to the light emitting unit. A disk is provided and the disk is positionable against an opposite side of the child car seat with respect to the magnet. In this way the magnet magnetically engages the disk for removably retaining the light emitting unit on the child car seat.

Abstract: A handset for operation and locking of an occlusion clearing device includes a body and movable cover. Valve(s) in fluid communication with tubing for aspiration or irrigation are located within the body. A locking mechanism having first and second components affixed at different points in the handset which are selectively movable relative to one another to transition between locked and unlocked positions. The first component is connected to and selectively movable relative to the cover. The second component engages a portion of the first component, causing the cover to move in an engagement direction as the first component is moved to a locked position. Movement of the cover in an engagement direction causes the valve(s) to change from a first to second position which controls the flow of fluid therethrough. An engagement surface of the second component engages and retains the first component in a locked position.

Abstract: A catheter shaft includes a first tube made of an extrudable copolymer that has reactive groups, and a second tube made of a polymeric material, which is welded to the first tube. A distal balloon is welded to the first tube.

Abstract: The present invention contemplates devices and methods to administer nutritional compositions and/or therapeutic drugs directly into a portal venous system. For example, total parenteral nutrition therapy may be administered directly into the hepatic portal venous system thus circumventing known side effects of conventional parenteral administration. Alternatively, hepatic diseases and disorders may be treated using locally administered therapeutic drugs. Devices capable of direct portal venous system administration include, but are not limited to, a direct portal access catheter or a transjugular access catheter.

Abstract: A medical device system may include a catheter sheath and a catheter shaft sized for delivery through a lumen of the catheter sheath. The catheter shaft may be coupled to an end effector at or adjacent a distal end of the catheter shaft. The catheter shaft may include a lumen and a control element. The control element may be coupled to the end effector and may reside within the lumen of the catheter shaft. Physical access may be provided to the control element, to allow the control element to be severed to facilitate removal of the end effector from a bodily cavity. The control element may include a lumen and a control cable therein. A liquid entry port may be provided in the lumen of the control element toward a distal end of the control element to allow expedited provision of fluid to a distal portion of the control element.

Abstract: A neuromodulation catheter includes an elongate shaft and a neuromodulation element. The shaft includes two or more first cut shapes and two or more second cut shapes along a helical path extending around a longitudinal axis of the shaft. The first cut shapes are configured to at least partially resist deformation in response to longitudinal compression and tension on the shaft and torsion on the shaft in a first circumferential direction. The second cut shapes are configured to at least partially resist deformation in response to longitudinal compression on the shaft and torsion on the shaft in both first and second opposite circumferential directions.

Abstract: A method of making a high flexibility distal zone on a neurovascular catheter is provided. The method includes the steps of dip coating a removable mandrel to form a tubular inner layer on the mandrel, coating the tubular inner layer with a tie layer, applying a helical coil to the outside of the tie layer, positioning a plurality of tubular segments, heating the tubular segments to form the high flexibility distal zone on the neurovascular catheter; and removing the mandrel.

Abstract: Disclosed is a module including: a base; a first drive member; and a second drive member. The second drive member is also mounted so as to be movable relative to the first drive member, in a degree of freedom other than rotational about the second axis, between a first and a second configuration. A motion transmission system transmits the driving movement generated by the drive motor to the second drive member in order to rotate the second drive member about the second axis between the first and second configurations.

Abstract: Some embodiments of a medical device anchor system include an anchor device that receives a medical instrument (such as a catheter or the like) and secures the instrument in place relative to a skin penetration point. In some circumstances, the anchor device may allow the anchor device to be used after medical instrument is already in place without the need for a second penetration point for the anchor device.

Abstract: A medical device includes an inflatable balloon defining an interior surface and an exterior surface, and a coating including a therapeutic agent disposed on the exterior surface of the inflatable balloon. The coating has a release transition temperature within a range from about 25° C. to about 50° C. When the temperature of the coating is below the release transition temperature, the coating retains at least a portion of the therapeutic agent on the exterior of the inflatable balloon. When the temperature of the coating is above the release transition temperature, the coating releases at least a portion of the therapeutic agent from the exterior of the inflatable balloon.

Abstract: An inflatable balloon is provided. The balloon includes a central lumen open at both ends of the balloon and connected to a gap formed in one sidewall of the balloon. This arrangement may provide the balloon with a generally C-shaped profile with the open central lumen within the balloon along a center axis thereof, such as to allow for perfusion. The balloon may also include an inflation port offset from a central axis and a shaft including an inflation lumen connected to the inflation port. A sheath may also be provided with a window through which the balloon may project in use.

Abstract: The present invention relates to applicators for administering microprojection arrays to skin and methods of administering microprojection arrays.

Abstract: Embodiments are disclosed of a method of controlling timing and/or dosage of a transdermal drug patch. For example, a control device operative to move the patch to one or more of a plurality of operational relationships with a skin of a patient, including being fully engaged with the skin, partially engaged with the skin, and disengaged with the skin. The device may include a roller that peels a patch on and off the skin. Optionally a convention patch is used. In some embodiments a patch and/or an adaptor has a mobile zone and an immobile zone. In some embodiments, an active surface of the patch fully contacts the skin in an engaged state. For example the patch may be attached to the device on a passive portion thereof.

Abstract: A syringe having an enteral collar with a vent is disclosed. The syringe may also include a plug which reversibly covers the vent. Other embodiments relate to the use of the syringe. The vent allows fluid within the region between the enteral collar and the tip to be removed.

Abstract: A catheter assembly and/or an introducer may include one or more features configured to guide a probe and/or a catheter distally through a septum. The catheter assembly may include a catheter adapter and the septum. The catheter adapter may include a distal end, a proximal end, and a lumen extending therebetween. In some embodiments, the septum may be disposed within the lumen. The septum may include a proximal surface that is tapered inwardly in a distal direction such that the proximal surface of the septum is configured to guide the probe and/or the catheter distally through the septum. The catheter assembly may be configured to receive an introducer, which may include an introducer element. A proximal end of the introducer element may include another proximal surface that is tapered inwardly in the distal direction such that the other proximal surface is configured to guide the probe or the catheter distally through the septum.

Abstract: A system includes a syringe adapter having a first end and a second end with the first end of the syringe adapter configured to be connected to a first container and the second end of the syringe adapter including a lock member having an open position and a closed position. The system also includes a vial adapter having a first end and a second end with the second end of the vial adapter configured to be connected to a second container and the first end of the vial adapter having a locking surface. The lock member includes at least one projection that extends radially outward. The syringe adapter has at least one corresponding projection configured to engage the at least one projection of the lock member to retain the lock member to the syringe adapter.

Abstract: A syringe apparatus for disinfection of central line port needleless connector and method of disinfecting a central line port needleless connector. The syringe apparatus includes a syringe tip including a first O-ring including a disinfectant located in a first section of a tip cavity between an inner tip portion of the syringe tip and an outer tip portion of the syringe tip. The syringe tip preferably further includes one or more Luer lock sections and one or more additional O-rings. The syringe apparatus preferably also includes a cap including an inner layer including a disinfectant.

Abstract: A catheter (20), which can be part of an intravascular blood pump, possesses a kink sensor which extends over the total length of the catheter and comprises an optical fiber (28A). The optical fiber is attached to an evaluation device (100) which evaluates a preset light quantity transmitted through the optical fiber as to whether a part of the light quantity is coupled out of the optical fiber along the length of the optical fiber. This is interpreted as a kink event and displayed. The optical fiber preferably utilized for the kink sensor is the optical fiber of an optical pressure sensor.

Abstract: Methods and devices for stimulating a nerve in a patient include emitting an electrical signal near a target nerve within the patient. The electrical signal comprises bursts with a frequency of 1 to 100 Hz. Each of the bursts has 2 to 20 pulses with a duration of about 50 microseconds to about 1000 microseconds.

Abstract: A multipart, non-uniform patient contact interface and method of use are disclosed.

Abstract: A method for manufacturing an implantable lead includes forming an elongated lead body core that defines a longitudinal axis. The elongated lead body core has a plurality of axially extending channels that are circumferentially spaced apart from one another around the elongated lead body core. The method also includes positioning an electrode ring around the elongated lead body core and electrical conductors. The method includes positioning a respective electrical conductor in each of the axially extending channels and positioning a dielectric insulator ring around the elongated lead body core and electrical conductors.

Abstract: Retainer devices and methods are configured for securing medical devices subcutaneously in a patient. The retainer device may include first and second arms connected by a bridge, the retainer clip configured to move between a first orientation in which lower surfaces of the first and second arms face each other, and a second orientation in which the first and second arms extend laterally from opposite sides of the bridge, wherein the clip is biased in the second orientation. Another example includes a coil and delivery device in which the delivery device holds the coil in a general straight configuration until release; when released the coil wraps about a medical device and holds the device to the subcutaneous tissue.

Abstract: A leadless cardiac pacemaker (LCP) is configured to sense cardiac activity and to pace a patient's heart and is disposable within a ventricle of the patient's heart. The LCP may include a housing, a first electrode and a second electrode that are secured relative to the housing and are spaced apart. A controller is disposed within the housing and is operably coupled to the first electrode and the second electrode such that the controller is capable of receiving, via the first electrode and the second electrode, electrical cardiac signals of the heart. The LCP may include a pressure sensor and/or an accelerometer. The controller may determine a pace time for a cardiac cycle based at least in part upon a signal from the pressure sensor.

Abstract: Methods and devices for improving pelvic floor dysfunction in a patient suffering therefrom by electrically modulating neural tissue in a minimally invasive fashion using an electrical micro stimulator are provided.

Abstract: Various aspects of the present disclosure are directed toward apparatuses, systems, and methods for delivering therapy to an adrenal gland of a patient. The apparatuses, systems, and methods may include a plurality of stimulation elements arranged configured to deliver stimulation energy through at least one of the plurality of stimulation elements to modulate aldosterone levels within the patient.

Abstract: Hemodynamic performance of a heart may be improved by determining, from a location associated with a diaphragm, an occurrence of a valid cardiac event; and then delivering asymptomatic electrical stimulation therapy directly to the diaphragm at termination of a diaphragmatic stimulation delay period that is timed relative to the occurrence of the valid cardiac event. The diaphragmatic stimulation delay period may be automatically established by sensing a plurality of cardiac events directly from a diaphragm; and for each of the sensed cardia events, determining whether the sensed cardiac event represents a valid cardiac event or a non-valid cardiac event. The diaphragmatic stimulation delay period is then calculated based on a plurality of sensed cardia events that are determined to be valid.

Abstract: A cochlear implant system comprising an external component having an external speech processor unit, and an internal component. The speech processor unit monitors one or more parameters, and the speech processor unit is configured to reduce the power consumption of the cochlear implant system in the absence of one or more parameters.

Abstract: Personalized network searching, in which a search query is received from a user, and a request is received to personalize a search result. Responsive to the search query and the request to personalize the search result, a personalized search result is generated by searching a personalized search object. Responsive to the search query, a general search result is generated by searching the general search object. The personalized search result and the general search result are provided to a client device, an advertisement is selected based at least in part upon the personalized search object, and the advertisement, the personalized search result, and the general search result are displayed.

Abstract: Systems, methods and devices for promoting recovery from a stroke induced loss of motor function in a subject. In certain aspects, the system includes at least one electrode, and an operations system in electrical communication with at least one electrode, wherein the at least one electrode is constructed and arranged to apply current across the brain of the subject and to record low frequency oscillations from a perilesional region of the subject. In certain aspects, provided is a method comprising placing at least one recording electrode in electrical communication in a perilesional region of the subject; placing at least one stimulation electrode in electrical communication with the brain of the subject; recording low frequency oscillations from the perilesional region of the subject; and delivering current stimulation to the brain of the subject.

Abstract: A method of neurostimulation titration. The method includes setting titration parameters for an electrical signal delivered by an implantable medical device, initiating titration with the titration parameters and an aggressiveness profile, performing titration by increasing at least one of a current amplitude, a frequency, a pulse width or a duty cycle of the electrical signal until a threshold is reached or a side effect is detected, pausing the titration while waiting for commands from the patient or caregiver, and resuming the titration in response to receiving authorization from an external device.

Abstract: A circuit for charge-balanced current-controlled stimulation. The circuit includes a transistor differential pair, a first current mirror, a second current mirror, and a third current mirror. The transistor differential pair includes a first differential input node, a second differential input node, a first differential output node, a second differential output node, and a common node. The transistor differential pair is configured to generate a first differential current that passes through the first differential output node and a second differential current that passes through the second differential output node. The first current mirror is configured to generate a first mirrored current based on the first differential current. The second current mirror is configured to generate a second mirrored current based on the second differential current. The third current mirror is configured to generate a third mirrored current based on the first mirrored current.

Abstract: The disclosed technology provides systems and methods of communication between implanted medical devices, e.g., implanted pulse generators, and handheld consumer devices, e.g., smartphones, via standard wireless communication protocols, e.g., Bluetooth or Bluetooth Low Energy (BLE) operating in the unlicensed 2.4 GHz frequency band.

Abstract: Embodiments of the invention are related to medical devices filled with a liquid composition, amongst other things. In an embodiment, the invention includes a hermetically sealed housing defining an interior volume, a component module disposed within the interior volume, the component module comprising a circuit board, the component module displacing a portion of the interior volume. A liquid composition can be disposed within the housing, the liquid composition filling at least 80% of the interior volume not displaced by the component module. Other embodiments are also included herein.

Abstract: Various aspects of the present disclosure are directed toward apparatuses, methods and systems that include implantable lead. The implantable lead may include an electrode arranged and a fixation element arranged about the lead body. The fixation element may extend circumferentially about the lead body.

Abstract: An EMI/energy dissipating filter for an active implantable medical device (AIMD) is described. The filter comprises a first gold braze hermetically sealing the insulator to a ferrule that is configured to be mounted in an opening in a housing for the AIMD. A lead wire is hermetically sealed in a passageway through the insulator by a second gold braze. A circuit board substrate is disposed adjacent the insulator. A two-terminal chip capacitor disposed adjacent to the circuit board has an active metallization that is electrically connected to the active electrode plates and a ground metallization that is electrically connected to the ground electrode plates of the capacitor. A ground electrical path extends from the ground metallization of the chip capacitor to the ferrule. A conductive ground pin is electrically and mechanically connected to the ferrule. The ground path comprises an internal ground plate disposed within the circuit board substrate.

Abstract: Implantable medical devices have a feedthrough from the device to the outside world to pass electrical current from electronics inside the implant to the patient or vice versa. A plurality of sensors and/or signal wires must connect to the feedthrough and implant in living tissue. Chemical and physical forces work against the wire connections. Embodiments of the present invention include a biocompatible cap or top, shaped to attach onto a rim of the feedthrough device. One or more wire bundle ports are included on the cap. One or two layers of a sealant (e.g., epoxy) can be injected under the cap. A first layer can rigidly protect the wire bonds, and an elastomeric silicone can cover the epoxy for a flexible protector. Other embodiments include an implant housing with a recess for the feedthrough; a top can protect the recess. One or more sealants can cover the feedthrough.

Abstract: An implantable medical device (IMD) with an inductive coil for wireless communication and/or power transfer. The inductive coil may be disposed about a housing of the IMD. The housing may include a magnetically permeable material that is configured to operate as a flux concentrator for concentrating non-radiative near-field energy through the inductive coil. In some cases, the near-field energy may be captured and converted into electrical energy that may be used to recharge a rechargeable power source of the IMD.

Abstract: A method and system for managing an implantable medical device (IMD) based on left ventricular hypertrophy (LVH) are provided. The method collects cardiac activity (CA) signals from one or more implantable electrodes at corresponding sensing sites. The method utilizes one or more processors to perform identifying a characteristic of interest from the CA signals, analyzing the characteristic of interest from the CA signals to identify an LVH state indicative of at least one of an occurrence or degree of LVH experienced by the patient, calculating a DFT expectation based on the LVH state and determining, based on the DFT expectation, at least one of i) a defibrillation shock parameter or ii) a maximum energy capacity of the IMD for implant.

Abstract: A device for influencing biological processes in living tissue, in particular a human body, for applying a pulsating magnetic field to at least a part of the tissue, includes a field generation device for generating the pulsating magnetic field and a pulse generator for actuating the field generation device. The pulse generator is designed such that the pulsating magnetic field includes a sequence of primary pulses, the pulse repetition rate of which is between 0.01 and 1000 Hz. The primary pulses are formed by a plurality of superimposed subpulses, wherein the primary pulses are overlaid by secondary pulses. The secondary pulses have a phase shift ? in relation to the primary pulses of ?0.5>?>0.5 and the phase shift ? is not equal to 0.

Abstract: A method and system for noninvasively treating a neurodegenerative disorder, can involve determining characteristics indicative of physical attributes of a central nervous system, the characteristics including parameters for diminishing adverse impacts of a magnetothermal stimulation treatment for a neurodegenerative disorder with respect to the central nervous system, and applying as a part of the magnetothermal stimulation treatment and based on the characteristics of the physical attributes of the central nervous system, a magnetic field to the brain for a thermal stimulation of neuron cells within the brain.

Abstract: A pain relief device and method or system to aid in the resolution of pain in a body including at least one layer of PVDF film and at least one other layer for directional purposes, as well as a polarizing layer. The device can be packaged in various ways. Also described is a device that uses a combination of LED bulbs, polymer based materials and a near field accelerator to provide pain relief.