Abstract: A leech therapy device adapted to latch a medicinal leech to a predetermined wound site is provided. The leech therapy device includes a conduit extending between a first end to a second end; an inner diameter of the conduit dimensioned to receive a medicinal leech, the inner diameter being less than twice a girth of the medicinal leech; and a cutout provided in the conduit closer to the first end than the second end; the cutout extending over a surface area between 100 and 150 squared millimeters. Wherein a user places a medicinal leech into the inner diameter, wherein a head of the medicinal leech is adjacent to the cutout, and then the user selectively positions said leech therapy device so that the cutout substantially circumscribed the wound site so that the medicinal leech can engage the wound site.

Abstract: A restraining device for an animal. A body having a base and two spaced-apart walls define a cavity to receive the animal. At least one pair of side restraining members is mounted to one of the walls of the body. Each restraining member is displaceable away from the wall and into the cavity to engage a side of the animal. An overhead restraining member is mounted to the body above the base. The overhead restraining member is displaceable toward and away from the base to engage the animal. A tightening mechanism is mounted to the body and has at least one rotatable rod. The first end of the rod has a rotatable handle to rotate the rod and the second end has a cam engaging one of the side restraining members. The handle rotates the cam and displaces the side restraining members into the cavity.

Abstract: Apparatus and methods are described for regulating blood flow in an ascending aorta of a subject including inserting a device into the ascending aorta. When in a deployed state, the device defines an inner surface that defines a conduit through the device, at least a portion of the inner surface diverging, such that a cross-sectional area of the conduit at the downstream end of the diverging portion is greater than a cross-sectional area of the conduit at the upstream end of the diverging portion. The device is deployed within a longitudinal portion of the ascending aorta, such that the device defines the conduit throughout deployment of the device within the longitudinal portion of the ascending aorta. Other applications are also described.

Abstract: A stent graft including a stent having a wall having at least one opening, an outer surface, and an inner surface and a covering of a composite material having a least one expanded fluoropolymer membrane and an elastomer is provided. The cover can be used to cover the outer and/or the inner surface of the stent. The expanded fluoropolymer membrane contains serpentine fibrils. In exemplary embodiments, the fluoropolymer is polytetrafluoroethylene. The composite material may be axially and/or circumferentially wrapped around the stent. The composite material is fold-free throughout its operating diameter range and exhibits a sharp increase in stiffness at a predetermined diameter. The stent graft can be designed to have a stop point in either a radial or axial direction. The stent graft can advantageously be implanted undersized with respect to a nominal diameter without having material infolding.

Abstract: A stent graft assembly with a sacrificial entry/exit port is disclosed. A first sacrificial port extends from a first branch stent graft and is configured to face a second branch stent graft when the stent graft assembly is in an expanded configuration. Likewise, a second sacrificial port can be provided, and can extend from the second branch stent graft and configured to face the first branch stent graft when the stent graft assembly is in the expanded configuration. The first and optional second sacrificial ports are configured to transition between (i) an open configuration to enable a guidewire or other surgical tool to pass from the first branch stent graft to the second branch stent graft while bypassing the main body, and (ii) a closed configuration to inhibit blood flow therethrough.

Abstract: A composite scaffold having a highly porous interior with increased surface area and void volume is surrounded by a flexible support structure that substantially maintains its three-dimensional shape under tension and provides mechanical reinforcement during repair or reconstruction of soft tissue while simultaneously facilitating regeneration of functional tissue.

Abstract: Implementations of a breast implant may include a shell including a posterior cephalic portion, a posterior caudal portion, an anterior cephalic portion, and an anterior caudal portion. Implementations of the breast implant may also include an anchor coupled within the shell and coupled directly and fixedly to the posterior caudal portion and the anterior caudal portion. The anchor may prevent rotation of the breast implant. The outer surface of the shell may be non-textured.

Abstract: In certain embodiments, a system for making an implant for an eye comprises a printer, a camera, and a computer. The printer prints material onto a target and has a printer head and printer controller. The printer head deposits the material onto the target, and the printer controller moves the printer head to deposit the material onto a specific location of the target. The camera generates an image to monitor the printing of the material. The computer stores a pattern for the implant, which is designed to provide refractive treatment for the eye; sends instructions to the printer controller to move the printer head to print the material onto the target according to the pattern; assesses the image from the camera according to the pattern; and adjusts the instructions in response to the image.

Abstract: An intraocular clip comprises a flexible body connected to a plurality of fasteners. The fasteners, at least two of them, are configured on opposite sides of the body in an opposing relationship, and wherein the fasteners are biased to be engaging their respective opposing fasteners on the opposite sides of the body, however manipulation of the body moves the fasteners away from each other until the body is released and the fasteners bias toward each other. The fasteners have a proximal end joined to the body and a distal end on the opposite end of the fastener from the body. The distal ends of the fasteners comprise footpads, and the footpads on opposing fasteners engage each other when the fasteners are biased in their closed positions.

Abstract: Intraocular implants and methods of making intraocular implants are provided. The intraocular implants can improve the vision of a patient, such as by increasing the depth of focus of an eye of a patient. In particular, the intraocular implants can include a mask having an annular portion with a relatively low visible light transmission surrounding a relatively high transmission central portion such as a clear lens or aperture. This construct is adapted to provide an annular mask with a small aperture for light to pass through to the retina to increase depth of focus. The intraocular implant may have an optical power for refractive correction. The intraocular implant may be implanted in any location along the optical pathway in the eye, e.g., as an implant in the anterior or posterior chamber.

Abstract: An intraocular lens (IOL) with a shape-changing optic is provided. The IOL includes an anterior face and/or a posterior face that is fabricated from a poly(dimethylsiloxane) elastomer having a durometer between about 30 Shore A to about 50 Shore A. A chamber is located between the anterior face and the posterior face and includes a silicone oil including diphenyl siloxane and dimethyl siloxane units. The silicone oil has a maximum viscosity of about 700 mm2/s at 25° C. and has a mean molecular weight of less than about 3,000 Daltons. An IOL is also provided that includes an anterior face and/or posterior face that is fabricated from a polysiloxane that is at least 99% poly(dimethylsiloxane) elastomer.

Abstract: Adjustable ophthalmic devices, systems including adjustable ophthalmic devices, and methods of adjusting an optical power of an ophthalmic device are described. In an embodiment, the ophthalmic devices include a body including an inner surface defining an aperture through the body, wherein the inner surface includes a feature selected from a sharp surface feature, a layer on at least a portion of the inner surface having a surface energy different than a surface energy of the inner surface, and a combination thereof. In an embodiment, the ophthalmic device includes two immiscible liquids disposed in the aperture defining a meniscus, wherein a curvature of the meniscus is defined at least in part by a position of an interface between the layer and the inner surface, a position of the sharp surface feature, or combination thereof.

Abstract: An exchangeable optics system includes an intraocular base that can be fixed within an eye. The intraocular base includes one or more couplers and a supporting structure. The one or more couplers releasably couple to an exchangeable optic or therapeutic and can include magnetic material. The supporting structure can include haptics and a main structure that physically supports the exchangeable optic or the therapeutic that is coupled via the one or more couplers. In some cases, the intraocular base can include a fixed lens within or on the main structure. The exchangeable optic can include corresponding one or more couplers, which may be formed of magnetic material. The therapeutic can be in the form of a magnetic particle.

Abstract: Systems, methods, and devices for inserting an intraocular lens (IOL) assembly into an eye may be provided. An apparatus for delivery of a lens component into an eye, including: a nozzle; a housing, wherein the nozzle is operatively coupled to the housing; a first lever; a second lever; and a linkage assembly. The linkage assembly may be disposed within the housing between and adjacent to the first and second levers. The linkage assembly may include a plurality of linkages pivotably coupled to each other, wherein the linkage assembly is collapsible.

Abstract: A prosthetic mitral valve may be anchored in a native mitral valve. The prosthetic mitral valve preferably has a large anterior prosthetic leaflet that spans the entire width of the native anterior leaflet and the anterior prosthetic leaflet moves away from left ventricular outflow tract during systole to create a clear unobstructed outflow path.

Abstract: Vascular valve systems for treating calcified vascular vessel valves by delivery of one or more calcium chelating agents are described. The vascular valve systems can include an expandable stent, a valve, and a material layer. The material layer includes a hydrogel, calcium chelating agent, and an acidifying agent. Methods of making the vascular valve systems are also described.

Abstract: A medical device for treating a heart valve insufficiency, with an endoprosthesis which can be introduced into a patient's body and expanded to secure a heart valve prosthesis in the patient's aorta. In an embodiment, the endoprosthesis has a plurality of positioning arches configured to be positioned with respect to a patient's aorta and a plurality of retaining arches to support a heart valve prosthesis. The endoprosthesis includes a first collapsed mode during the process of introducing it into the patient's body and a second expanded mode when it is implanted.

Abstract: Apparatus for attaching a prosthetic tether between a leaflet of a patient's heart valve and another portion of the patient's heart to help prevent prolapse of the leaflet and/or to otherwise improve leaflet function. The apparatus can be used with relatively low invasiveness of the patient's body. The apparatus releasably clamps the leaflet during attachment of the tether to the leaflet. The apparatus may include an integrated display for indicating how extensively the leaflet is being clamped, as well as structure for stabilizing the leaflet for better clamping. The apparatus may enter the heart through an aperture in the wall of the heart, and may include structure for helping to reduce blood leakage from that aperture. The apparatus may be able to enter the heart by following a guide wire. The apparatus may include various means for attaching the tether to the leaflet.

Abstract: The present disclosure relates to heart valve prostheses, delivery devices, actuation handles, and other improved devices and methods that facilitate delivery of a heart valve prosthesis to a defective native valve structure in a patient, such as the aortic valve.

Abstract: The disclosure provides systems and related methods for delivering a prosthesis to a target location. The system includes a tether delivery catheter and a prosthesis delivery catheter, and also can include a lock delivery catheter or knot pusher, as desired. Various embodiments of useful valve prostheses are also disclosed.

Abstract: A catheter and a method for using the catheter to implant a replacement aortic valve into a patient. The catheter includes an expandable wall, an outer sheath, a first tube operably coupled to the expandable wall, and a second tube operably coupled to the expandable wall. The catheter also includes a pusher that is fixed to the second tube, the pusher being spaced apart from the expandable wall by a distance that is sufficient to accommodate the replacement aortic valve. The outer sheath is movable relative to the expandable wall so that in one state the expandable wall is disposed within the outer sheath and in another state the expandable wall is located outside of the outer sheath. The expandable wall is configured to radially expand. The catheter also includes a handle assembly that is adjusted by a surgeon to achieve the functions of the catheter.

Abstract: A method of treating diastolic heart failure includes implanting a cardiac implant in a heart of a subject diagnosed as suffering from diastolic heart failure. A superior portion of a flexible tether of the cardiac implant is anchored to one or more left-atrial sites of one or more walls of the left atrium. An inferior portion of the flexible tether is anchored to a site of a wall of a mid third of the left ventricle, of a wall of an apical third of the left ventricle, and/or of a papillary muscle of the left ventricle. As a result, the flexible tether reduces a volume of the left atrium during at least a portion of ventricular diastole of each cardiac cycle, thereby enhancing ventricular filling. Other embodiments are also described.

Abstract: The invention relates to a connecting sleeve for anchoring shafts of two oppositely arranged prostheses, preferably on an elongate bone such as a femur or humerus. The reinforcing sleeve comprises two receiving bushes (1, 2) for one prosthesis shaft each and comprises a separable coupling region (3) arranged therebetween for connection in such a manner as to resist shear forces and rotation. According to the invention, each receiving bush (1, 2) has, on the side thereof facing the coupling region, one fork (31, 32) of a pair of forks that interact with each other, and a fitting block (4) is arranged on a base of the fork, the lateral surfaces (44) of which fitting block have a distance that corresponds to an inner width of the fork, and the lateral surfaces (44) are designed to contact flanks of the fork in a planar manner, at least one fastening screw (5) being arranged transversely through the fork. The fork connection is simpler to produce than the known wedge connection and yet is sufficiently robust.

Abstract: An augment device for a joint endoprosthesis, the device including a sleeve surrounding a channel extending through the sleeve. The sleeve is formed of porous material for ingrowth of bony material, the sleeve comprising an inner face and an outer face. The sleeve further comprises a wall surrounding the channel, the wall being made of solid material and forming a sandwich structure with the porous material, wherein the wall forms a bulkhead between the inner face and the outer face. Thereby, the bulkhead wall will stop inflow of any cement across the sleeve from its inner to its outer face. The porous material on the outer face will be kept free from cement and its capability to promote bone ingrowth is reliably preserved. The augment devices are preferably provided as a set having different sizes and straight or stepped bottoms for improved versatility and maximum preservation of natural bone matter.

Abstract: An interbody spacer for spinal fusion surgery includes first and second opposite side walls that have open-cell metal foam at upper and lower faces, and a three-dimensional lattice disposed between open-cell metal foam at the upper and lower faces. The open-cell metal foam is in communication with the three-dimensional lattice so that bone growth can enter the three-dimensional lattice from the open-cell metal foam. The interbody spacer may be formed by additive manufacturing.

Abstract: An intervertebral disc is provided having an upper plate, a lower plate, and a core. The upper and lower plates include outer vertebral body contacting surfaces which are provided with attachment enhancing features to ensure bone integration. The attachment enhancing features shown include one or more fins, serrations and teeth. An opposite surface of the plates from the vertebral body contacting surfaces is formed with a recess which serves as a bearing surface for the core. In order to form an intervertebral disc with a lower disc height, at least one of the recesses is provided opposite a corresponding dome shaped portion on the vertebral body contacting surfaces. This allows the plates to be formed with a thinner profile for a smaller overall disc height. In addition to providing a lower overall height to the artificial disc, the dome shaped portion of the plates also provides a more anatomically shaped outer vertebral body contacting surface.

Abstract: A knee prosthesis for total knee replacement has femoral and tibial joint components. The femoral component has a medial condyle, a lateral condyle and an intercondylar recess between the condyles. The condyles have in sagittal profile a spiral outer surface with increasing anterior-to-posterior radii of curvature, such as radii that follow a Fibonacci sequence ratio per every quadrant. The tibial component is lateral-medial mirror symmetric in coronal profile and has shallow concave medial and lateral condyle surfaces for receiving corresponding condyles of the femoral component as bearing surfaces when the femoral and tibial components are biased together under applied tension by ligaments. The shallow concave condyle surfaces in sagittal profile have sharp radii of curvature near anterior and posterior ends of the condyle surfaces that can accommodate up to 5° anterior and up to 6° posterior misplacement error and up to 4° rotational mismatch between the femoral and tibial components.

Abstract: An orthopaedic implant includes a patella component having a metal base with a polymer bearing molded thereto. A method for making a patella component is also disclosed.

Abstract: The invention relates to a prosthesis for implantation into a living body in the form of a magnetic artificial joint, in particular an artificial shoulder joint, comprising: a) a first prosthesis member comprising a socket member, b) a second prosthesis member comprising a head member, c) one of the socket member and the head member is at least partially composed as a permanent magnet and the other one of the socket member and the head member is at least partially composed of a magnetic material, or the socket member and the head member are both at least partially composed as a permanent magnet, d) the socket member comprises a recess on a surface side to be coupled with the head member, the recess comprising a concavely contoured contact surface, e) the head member comprises a projection on a surface side to be coupled with the socket member, the projection comprising a convexly contoured contact surface, f) the convexly contoured contact surface is adapted to the concavely contoured contact surface, such th

Abstract: An ankle prosthesis has a tibial component configured for attachment to a tibia of a person, and a talar component. The talar component has a first surface configured for facing the tibial component and a second surface configured for facing a talus of the person. The second surface has first and second arms attached to it, for pivoting or flexing outwardly in medial and lateral directions, respectively, to engage side surfaces of a previously formed slot in the talus.

Abstract: A prosthetic ankle includes a tibial portion likely to be connected to the lower end of a tibia, a talus portion likely to be connected to a talus, and a pad inserted between the tibial portion and the talus portion. The tibial portion includes an articular surface likely to engage with a contact surface of the pad. The talus portion includes a curved articular surface likely to engage with a contact surface of the pad. The articular surface of the tibial portion is curved, concave and includes a flat section forming an extension to the rear of said articular surface.

Abstract: An implant stabilizes two adjacent bones of a joint, while enabling a natural kinematic relative movement of the bones. Support components are connected to each bone of the joint, and a flexible core is interposed between them. The core and at least one of the support components are provided with a smooth sliding surface upon which the core and support component may slide relative to each other, enabling a corresponding movement of the bones. The surfaces may have a mating curvature, to mimic a natural movement of the joint. The core is resilient, and may bend or compress, enabling the bones to move towards each other, and or to bend relative to each other.

Abstract: Expandable fusion devices, systems, instruments, and methods thereof. The expandable fusion implant may include an upper endplate assembly and a lower endplate assembly. The upper and lower endplate assemblies may be configured to expand in width. A rotatable actuator may move one or more driving ramps, which mate with an upper ramp and a lower ramp, respectively. The actuator may cause independent movement of one or more of the driving ramps, thereby causing an expansion in height of the upper and lower endplate assemblies.

Abstract: A spinal implant has a first member defining a longitudinal axis. A second member includes an axial cavity configured for disposal of the first member. A third member is rotatable relative to the first member and defines a transverse cavity. A locking element is disposable in the transverse cavity and engageable with the first member to fix the third member relative to the first member. Systems and methods of use are disclosed.

Abstract: A spinal implant comprises a proximal member including a body having a first diameter and a head having a second diameter. The body includes an outer surface disposed for non-fixation with a superior facet of a vertebra, and the second diameter being greater than the first diameter. The spinal implant comprises a distal member having a third diameter and being configured for fixation with an inferior facet of an adjacent vertebra. Systems, surgical instruments and methods are disclosed.

Abstract: A minimally invasive surgical procedure for replacing a hip joint is provided. A main incision is initiated at a point being a projection of a tip of a greater trochanter and extends proximally about a distance in the range of from 1 cm to 8 cm in line with the femoral axis. An inline capsulotomy is performed, while keeping muscles and posterior capsule intact, to expose the hip joint capsule for accessing the hip joint. The femoral canal is prepared for receipt of a femoral implant. The femoral head is resected and removed out of the acetabulum. A step of acetabular preparation is performed using a retractor comprising two tip rails, each tip rail having a plurality of tines. Related tools, devices, systems and methods are also provided.

Abstract: Devices, systems and methods are provided for facilitating knee balancing during a knee replacement surgery. A system can include a force sensor, a main body, a moveable sensor platform, and an adjustment mechanism. The force sensor can sense one or more forces applied within a knee joint, including forces applied on a medial side and a lateral side. The movable sensor platform can be coupled between the force sensor and the main body. The adjustment mechanism can adjust the moveable sensor platform, relative to the main body, thereby adjusting a collective height of the system. A method can include inserting portions of a knee balancing system into a gap formed between a cut distal end of a femur and a cut proximal end of a tibia, adjusting an adjustable mechanism of the system to increase or decrease a collective system height, and sensing and displaying the medial and lateral forces.

Abstract: An implant device for use in achieving spinal fusion, includes an implant having an implant body. The device includes a graded radiopacity calibration tool integrated with the implant body. The tool has a plurality of graded levels of radiopacity representative of a range of bone density parameter amounts. Each of the graded levels corresponds to a different bone density parameter amount. A method is provided that uses the device to determine a degree of one of bone maturity, strength, osteoporotic state, state of healing and state of degrading bone tissue based on a comparison of a bone at the site in the image and radiopacity correlated from a calibration standardized curve defined by the standard, with a range of grey levels representative of degrees of one of the bone maturity, the strength, the osteoporotic state, the state of healing and the state of degrading bone tissue.

Abstract: A wrist device for a prosthetic limb is provided. The device (1) comprises a base member (3) connectable to the wearer of the device, and a support member (13) connectable to the limb. The support member (13) is pivotably connected to the base member (3) such that the support member can pivot about a pivot axis (A) relative to the base member. A damping mechanism is located between the base (3) member and the support member (5). The damping mechanism comprises a pinion (47) connected to the support member (5) and rotatable about the pivot axis (A) relative to the base member (3). A rack (35) is engaged with the pinion (47) such that rotational motion of the pinion causes a linear motion of the rack, and at least one biasing member (41) extends between the base member (3) and the rack. The biasing member (41) biases the rack (35) and support member (13) into a neutral position. A prosthetic limb incorporating the wrist device is also provided.

Abstract: A prosthetic system includes a prosthetic foot having an upper foot element with a concave-forward facing portion and foot portion extending forwardly therefrom. An intermediate foot element is disposed below the upper foot element and has a front portion coupled to the foot portion of the upper foot element. A lower foot element is disposed below the intermediate foot element. A pump system is coupled to the prosthetic foot and comprises a pump mechanism including a housing defining a cavity, and a membrane situated in the cavity. The pump mechanism is movable between an original configuration and an expanded configuration. An arm member is connected to the pump mechanism and operatively coupled to the intermediate foot element. The arm member is arranged to move the pump mechanism toward at least the expanded configuration upon movement of the intermediate foot element relative to the upper foot element.

Abstract: A method of treating an aneurysm, including determining a diameter associated with a vessel having the aneurysm; selecting one of a plurality of braided implants for treating the vessel, wherein each braided implant comprises a porosity substantially consistent over up to a 1 mm diameter range, each braided implant configured to provide consistent porosity over different diameter ranges; and treating the vessel with the one of the plurality of braided implants.

Abstract: Methods for securing strand ends of devices configured for insertion into an anatomical structure, and the resulting devices.

Abstract: A stent includes a high radial/crush force segment and a highly flexible segment. In an aspect, a plurality of first ring struts connected such that each of the plurality of first rings comprises a sinusoidal pattern having a plurality of apices and troughs, each first ring connected to an adjacent first ring by at least one connector. The connector extends from a ring strut of the first ring from a position near an apex of the first ring to a ring strut of the adjacent first rings near an apex of the adjacent ring, and a second stent segment comprises a plurality of second rings connected to one another to form a series of second rings.

Abstract: Various embodiments relate to a stent assembly comprising a stent; a swellable coating disposed on at least a portion of an exterior surface of the stent; optionally, a carrier dispersed in the swellable coating and/or disposed on at least a portion of an exterior surface of the stent; and an active agent comprised in at least one of the swellable coating or the carrier, if present. Use of the stent assembly as a ureteric stent, and method of preparing a stent assembly are also provided.

Abstract: A stent graft delivery system and method of operating the same are disclosed. The system includes a stent graft cover, a screw gear, and a handle assembly. The handle assembly includes an external slider configured to rotate about the screw gear, and a central hub configured to slide linearly along the screw gear as the external slider is rotated. The central hub defines a main lumen port extending therethrough and configured to receive the stent graft cover, and a branched lumen port configured to receive a branched lumen. The stent graft cover can be fixed to and within the main lumen port. Rotation of the handle causes the central hub to slide linearly, which simultaneously retracts the stent graft cover and the branched lumen.

Abstract: A dorsiflexion (or eversion) assistance device attaches around an ankle and foot, such us over footwear. A tensioned cord is extended between a portion attached to the ankle and a portion attached to the foot. This tensioned cord is attached to one of a plurality of portals of a connector attached to the ankle and connector attached to the superior side of the foot depending on a need for greater assistance on a left, medial, or right side. The connector on the ankle can be a bearing movable or rotatable front/back, left/right and around so as to allow the tensioned cord to move as the wearer walks as well as angle the tensioned cord in a resting or walking state.

Abstract: A system for reducing forces which, in particular, act on a spine of a human, includes a plurality of joinable exoskeleton elements, wherein at least two of the joinable exoskeleton elements are configured to be fastened to the human body during use of the system and wherein a first exoskeleton element of the joinable exoskeleton elements includes a guide which is configured to guide a second exoskeleton element of the joinable exoskeleton elements along a curved trajectory relative to the first exoskeleton element and to enforce a superimposed translational and rotational relative movement between the first exoskeleton element and the second exoskeleton element when guiding the second exoskeleton element along the curved trajectory relative to the first exoskeleton element.

Abstract: Custom manufactured headwear for a subject's head is provided. The headwear comprises an inner layer deposited by an additive manufacturing device. The headwear further comprises an outer layer deposited by the additive manufacturing device. The inner layer and the outer layer are each formed by the additive manufacture device utilizing a device data file derived from a subject data file. The subject data file is representative of the shape of the head and the device data file determining the shape of the headwear.

Abstract: Halo vests and the construction methods thereof are provided. The halo vests are designed in unibody structures to minimize the number of components. A 3D scanner is utilized to scan a subject to obtain parameters for a modeling program, which help to construct an optimized halo vest for the subject by printing rather than assembling manually. The subject can easily put on the halo vest without miscellaneous steps.

Abstract: The present invention provides a fluid-carrying application, comprising: a first sheet with a first surface and a second surface; a second sheet with a third surface and a fourth surface, wherein a part of the third surface and a part of the second surface of the first sheet are welded or adhered to at least one band-shaped region, thereby forming a first chamber having at least a first drainage port, and the inside of the chamber can communicate with the outside through the first drainage port; an adhesive layer, which is provided on the fourth surface of the second sheet; and a release layer, which covers at least a part of the adhesive layer, wherein, the first drainage port is formed at the first sheet or an open portion where the first sheet and the part adjacent to the edge of the second sheet are not welded or adhered to each other.