Abstract: Infusion devices including a cannula have a tubular body member comprising a tubular wall enclosing a longitudinal extending internal bore. The cannula is adapted to flex in response to a compression force and/or an increased internal pressure in the cannula.

Abstract: Valves and medication delivery systems including valves are described herein. A valve includes a valve body and a valve element. The valve body defines a first flow path, a second flow path, and a catheter flow path. The valve element is disposed within the valve body, wherein the valve element is configured to permit fluid communication between the first flow path and the second flow path in a priming position, and is configured to permit fluid communication between the first flow path and the catheter flow path in a dispensing position.

Abstract: A multi chamber syringe unit includes a body, a separating element and a bypass arrangement. The body has a distal end side, a proximal end side opposite to the distal end side, an interior limited by a side wall between the distal end side and the proximal end side and a longitudinal axis centrally extending from the distal end side to the proximal end side through the body. The separating element is arranged in the interior of the body forming a distal chamber between the distal end side and the separating element and a proximal chamber between the proximal end side and the separating element. The bypass arrangement is a section of the body in which the interior has a constant noncircular cross section orthogonal to the longitudinal axis. The multi camber syringe unit allows for being efficiently prepared and for efficiently providing or administering high quality of prefilled products.

Abstract: A drug delivery device includes a container for storing a drug, the container having a stopper for expelling the drug; an injection drive comprising an energy source for directly or indirectly acting on the stopper to expel the drug; a sensor for detecting contact between the drug delivery device and a body of a patient; and a user interface (UI) for activating or causing the activation of the injection drive. The device is operative for drawing attention to the UI, if the sensor detects contact between the drug delivery device and the body of the patient, to thereby indicate that the injection drive is ready to be activated, which activation is the next step in the drug administration process.

Abstract: A drug delivery device for administering a drug is presented having a body, at least one electrical unit and a port for electrically contacting the electrical unit, an adapter for attaching an injection needle to the drug delivery device, a safety mechanism arranged to prevent contacting the electrical unit whilst an injection needle is in fluid communication with the drug delivery device and arranged to prevent establishing a fluid communication whilst the electrical unit is contactable.

Abstract: A drive assembly for a drug delivery system including a plunger member configured to engage and move a stopper within a container, a biasing member configured to move the plunger member, and an adjustable spacer assembly positioned between the plunger member and the stopper. The spacer assembly includes a spacer element attached to the stopper and at least one shim or includes a spacer element and a holder to which the spacer element is attached. The holder may be attached to the stopper and the spacer element may be attached to the holder by a threaded engagement. Also, a drug delivery system for injecting a medicament, the system including a container configured to receive a medicament, the container comprising a stopper configured to move within the container and a closure, a drive assembly as described above, and a needle actuator assembly.

Abstract: A medicament delivery device for injections or inhalations comprises a supplementary device affixed to it. The supplemental device is provided with an optical system for monitoring a dosage of medicament. The optical system is able to receive reflected and refracted optical images of the dosage value as the optical signals from the medicament delivery device and thus keep a dosage window on the medicament delivery device free for direct monitoring by a user due to changing the transferring of the optical signal direction. The supplemental device is able to analyze, record and display the dosage and the other relevant data on a display and inform the user. The supplemental device is also able to transmit the medicament delivery data to an external device. A method for collecting the medicament delivery data including the medicament dosage information from a dosage setting mechanism and controlling the dosage, recording and displaying the dosage data by the supplemental device on its display is disclosed.

Abstract: Data collection devices for attachment to injection devices are disclosed. In one embodiment, the data collection device includes: a body attachable to a dial member of the injection device, a sensor arrangement comprising a sensor and a scale, and a processor. The sensor is configured to detect a rotation of the body relative to a trigger of the injection device. The processor is configured to detect a rotation of the body relative to the trigger. One of the sensor and the scale is arranged in or on the body and wherein the other one of the sensor and the scale is located on the trigger or is rotationally lockable to the trigger configured to detect a rotation of the body relative to the trigger.

Abstract: A method of verifying that a first unit and a second unit being mounted to each other are correctly paired, the first unit comprising a first visual identifier and the second unit comprising a second visual identifier, the method comprising the steps of (i) capturing an image of the first and second unit mounted to each, the image comprising both the first and the second visual identifier, and (ii) processing the captured image to (a) identify the first and the second visual identifier, and (b) determine whether the captured identifiers represent a predefined combination of visual identifiers to thereby verify the pairing.

Abstract: The disclosure relates to a drug delivery device, comprising a mechanical audible indicator capable of producing an audible signal with a volume of at least 100 dB.

Abstract: A sensing system for determining a zero position of a medication delivery device. The sensing system includes at least one actuator member, a biasing member, a stop surface and a sensor. The stop surface is structured and arranged within the device housing for abutment by a push surface of the at least one actuator member as a screw element of the device screws to a zero position from a dosing position. The abutment forces the at least one actuator member to move relative to the screw element from a first position to a second position against a resistance provided by the biasing member. A sensor within an electronics module is adapted to recognize the at least one actuator member at the second position.

Abstract: A medicament delivery device and a controller is disclosed. The medicament delivery device includes a medicament container, plunger rod and a resilient member. The plunger rod is in contact with a slidable stopper within the medicament container for expelling a medicament. The resilient member is used for applying a force to the plunger rod upon a delivery of the medicament. In addition, the controller is configured to detect a completion of a delivery stroke of the plunger rod according to an inductive property of the resilient member.

Abstract: An automatic injection device includes an injection syringe for injecting liquid provided with a syringe body carrying an injection needle and a piston rod mounted to be able to move inside this syringe body to cover an injection stroke during which the liquid is injected, an external casing and a positioning control member that are telescopic, the relative movement of which controls the operation of the automatic injection device, and control members arranged to selectively control the movement of the syringe body and the movement of the piston inside the positioning control member in order to automatically inject the liquid present in the injection syringe, the automatic injection device further comprising a device for generating sound signals activated during the automatic injection of the liquid present in the injection syringe so as to generate a series of sound signals from the start to the end of the injection.

Abstract: A drug delivery device is provided comprising a drug-filled cartridge or means for receiving a drug-filled cartridge, and drug expelling means comprising expelling means for expelling an amount of drug from the cartridge, and an indicator member arranged to move corresponding to an action performed on or by the drug delivery device. The device further comprises an energy source, wireless communication means, sensor means adapted to detect movement of the indicator member, and a processor adapted to (i) receive input from the drug delivery device indicative of indicator member movement and (ii) control the communication means to transmit a data signal comprising coded information derived from received input from the sensor means, wherein the wireless communication means is in the form of a sound transducer.

Abstract: An administration assembly for a medicament delivery device is presented having a plunger rod, a plunger rod holder and an activation sleeve configured to receive a portion of the plunger rod holder. The triggering member is configured to move the activation sleeve from a first position to a second position relative to the plunger rod holder. The plunger rod is configured to be axially locked relative to the plunger rod holder when the activation sleeve is in the first position. The plunger rod is released from being axially locked when the activation sleeve is moved towards the second position.

Abstract: A medical waste disposal and container washing system includes loading and unloading stations, the loading station configured for placing a medical waste container on a conveyor system. An inversion station is located downstream along the conveyor system, operable to reorient the container from a first orientation in which medical waste is retained to a second orientation in which the medical waste is discharged from the medical waste container by gravity as the medical waste container is moved within the inversion station. A first wash station along the conveyor system washes an interior of the container that has been reoriented. A second wash station is located downstream along the conveyor system.

Abstract: A magazine assembly (1) that stores a plurality of needles (56) configured to engage a medication pen (2) via an adapter (4) for medication delivery, the magazine assembly (1) comprising a magazine housing (20) enclosing a plurality of hub chambers (22) each enclosing one of a plurality of needle hubs (50), a connector (28) in each of the plurality of hub chambers (22), each connector (28) engages one of the plurality of needle hubs (50), and a plurality of enclosures (30) each sealing the plurality of hub chambers (22), wherein a selected enclosure of the plurality of enclosures (30) is removed to expose a selected needle hub (52) of the plurality of needle hubs (50), the adapter (4) attaches to the medication pen (2) to engage the selected needle hub (52) while disengaging the selected needle hub (52) from the hub chamber (22), and the selected needle hub (52) is removed from the magazine housing (20) to prepare the medication pen (2) for medication delivery.

Abstract: An object of the present invention is to provide a tamper-evident structure of syringe that enables a user to recognize at a glance the fact that the syringe is already unsealed. A cap 4 of the syringe 2 includes a cover 5 that covers a distal end of a nozzle 21, a sealing plug 7 that is elastic and seals the distal end of the nozzle 21 in a state of being attached to the inside of the cover 5, and a tamper ring 6 that includes a restraining part that is separably connected to the syringe 2 and the cover 5 that presses the sealing plug 7 against the distal end of the nozzle 2.

Abstract: There is provided a mesh for use in forming droplets of liquid in a nebuliser, the mesh comprising a first portion (22) made of a first material having a plurality of holes passing therethrough; and a second portion (26) made of a second material that is in contact with the first portion (22), the second portion (26) having a corresponding plurality of holes passing therethrough, the plurality of holes in the second portion forming nozzles (28) for an outlet side of the mesh; wherein the first material has a higher density than the second material.

Abstract: Method for detecting leaks and/or verifying adequate closure following a medical procedure, on a hollow or tubular organ of a subject, wherein a leak test is performed by injecting or insufflating, in the concerned organ, a specific test gas which is not commonly produced or naturally present within the body of the subject, or which is present or produced in a precisely known amount or concentration, and by analyzing percutaneously the gas or gas mixture present locally within the body cavity in which the organ is situated, and then verifying the presence, and preferably determining the concentration, of the injected or insufflated test gas in the local gas or gas mixture of the body cavity and indicating whether the concerned organ or a lumen defined by the latter is leak-free or not.

Abstract: A rupturing system for an aerosol-generating system is provided, the rupturing system including a first tube and a second tube being movable relative to each other along a first motion path from a first position to a second position, such that the defined volume is larger in the first position than in the second position; a rupturing member connected to one of the first tube and the second tube, the rupturing member being arranged such that in the first position the rupturing member is contained completely in the defined volume of the first tube and the second tube, and in the second position the rupturing member at least partially protrudes from the defined volume and is configured to rupture a container; and a first wrapper overlying at least a portion of the first tube and being attached to the first tube.

Abstract: At least one example embodiment discloses a pod for an electronic vapor (e-vapor) apparatus. The pod includes a pre-vapor formulation compartment configured to hold a pre-vapor formulation therein, a device compartment in fluidic communication with the pre-vapor formulation compartment, the device compartment including a processor configured to monitor the pre-vapor formulation compartment and identify the pre-vapor formulation and a vapor channel extending from the device compartment and through the pre-vapor formulation compartment.

Abstract: A system may include a mobile application residing on an external device and an inhalation device. The inhalation device may include a mouthpiece, a mouthpiece cover, medicament, and an electronics module comprising a processor. The inhalation device may be configured to both prepare a dose of medicament for delivery to a user and cause the processor to transition between power states when the mouthpiece cover is moved from a closed position to an open position to expose the mouthpiece. The electronics module or the mobile application may be configured to generate usage events based on usage of the inhalation device by the user. The electronics module may also include a pressure sensor, and the electronics module or the mobile application may be configured to determine whether a usage event is a good inhalation event, a fair inhalation event, or a no inhalation event based on feedback from the pressure sensor.

Abstract: According to at least one example embodiment, a controller for an e-vaping device includes a movement sensor configured to detect movement of the e-vaping device and output an output signal based on the movement. The controller includes control circuitry configured to control power supplied to power consuming elements of the e-vaping device based on the output signal.

Abstract: Example embodiments relate to a cartridge configured to house a pre-vapor formulation for an e-vaping device, the cartridge including an inner portion and an outer portion configured to store the pre-vapor formulation. The outer portion includes a plurality of fibers configured to be mobile and/or configured to be substantially free of entanglement with one another. The fibers are configured to be substantially free of entanglement with one another based on the lengths of the plurality of fibers. For example, the lengths of the plurality of fibers may be in a range of about 3 mm to about 7 mm. The lengths may also be about 5 mm.

Abstract: A respiratory acoustic device is provided that is easy to operate and transport. The device delivers vibrations artificially to the lungs and airways to fluidize mucus adhering to the airways and promote its discharge. A respiratory acoustic device 1 is provided with a housing 10, and a mouthpiece 20 that is in communication with the housing 10. The housing 10 has a reflecting end 12 for reflecting air that has been blown in from the mouthpiece 20 and an open end 13 through which air that has been blown in from the mouthpiece 20 can escape. If a sudden exhalation such as a cough is blown into the housing 10 through the mouthpiece 20, the device causes the noise due to said exhalation to resonate with the oral and lower airway cavities, and vibrate the user's lungs and airways with the low frequency acoustic shock waves generated therein.

Abstract: A device for placing a lung in a variety of different inflation states using positive air pressure. An exemplary device includes a housing and an air supply component. The housing includes a platform receives at least one of a synthetic lung or a real lung. The platform is at the same air pressure as a surrounding environment. The air supply component is located within the one or more internal cavities of the housing. The air supply component inflates the synthetic lung or the real lung with positive pressure.

Abstract: Methods and system for treating obstructive sleep apnea and snoring are disclosed. The system generally comprises a mask for delivering pressurized air to patient's breathing orifice, a sensing mechanism for continuously assessing the state of patient's breathing and a pressure generator for generating the pressurized air in the mask. The pressurized air is applied to the breathing orifice only during selected portions of the breathing cycle, when such pressure might be required to prevent occlusion of the airway or to restore patency of the airway after such occlusion occurs.

Abstract: A breathing apparatus includes a control unit configured to control operation of the breathing apparatus based on at least a first input value and a second input value. The breathing apparatus also includes a graphical user interface connected to the control unit. The control unit is configured to display a visual output on the graphical user interface including an area defined by a first axis and a second axis. In addition, the breathing apparatus includes an input unit configured to provide selection of a portion of the area. The control unit is configured to set the first input value in response to the position of the selected portion relative the first axis and to set the second input value in response to the position of the selected portion relative the second axis.

Abstract: An insertion guide facilitates insertion of an endotracheal tube (ETT) into the trachea of a patient instead of the esophagus of the patient. The ETT includes an elongated, somewhat flexible, generally hollow tube and the insertion guide includes an elongated, solid and relatively rigid shaft that is configured to be positioned within the hollow tube of the ETT. The shaft is provided with a radiused portion and/or an angled portion adjacent a distal end of the insertion guide that protrudes outwardly beyond a distal end of the ETT. The radiused portion and/or the angled portion of the shaft facilitate insertion of the distal end of the ETT past the epiglottis and into the trachea of the patient instead of into the esophagus of the patient.

Abstract: A seal-forming structure for a patient interface may include a patient-contacting surface configured to engage the patient's facial skin to form a seal; a posterior opening formed in the patient-contacting surface, the posterior opening configured to provide the flow of air at said therapeutic pressure to the patient's nares; and a support structure extending from the patient contacting surface to an interior surface of the seal-forming structure, the support structure and the interior surface forming a continuous loop, wherein the patient interface is configured to allow the patient to breath from ambient through their mouth in the absence of a flow of pressurised air through the plenum chamber inlet port, or the patient interface is configured to leave the patient's mouth uncovered.

Abstract: Headgear for use with a respiratory mask is described. The headgear comprises a continuous and substantially curved elongate member extending in use below a user's nose and at least two headgear straps capable of attachment to the ends of the elongate member. A mask attachment on the elongate member is disposed to sit below or on one of said user's nose, mouth, upper lip and an inlet to the mask. The attachment is capable of receiving the mask.

Abstract: A nasal pad for respiratory mask and a respiratory mask. The nasal pad comprises a nasal pad body and nasal plugs. Each nasal plug comprises a nasal plug body. The nasal plug bodies are fixedly connected to the nasal pad body. The nasal pad body comprises extend-retract adjustment sections. The extend-retract adjustment sections are provided with an extended length and a retracted length. The extend-retract adjustment sections are configured in a way that the length thereof can be adjusted between the extended length and the retracted length, thus varying the distance between the two nasal plug bodies. One purpose of the nasal pad is for use in the respiratory mask.

Abstract: An adapter configured to allow interconnection of a device input connector (DIC) having a first connector configuration and an consumable end connector (CEC) having a second connector configuration, the adapter including a first end having a first connector mateable with the DIC, a second end configured to receive at least part of the CEC, a locking mechanism configured to lock the CEC to the adapter, and a release mechanism configured to release the CEC from the adapter.

Abstract: An apparatus for humidifying a flow of pressurised, breathable air includes varying a first pressure of the flow of breathable gas to vary a level of thermal engagement between the conductive portion of the reservoir and the heater plate, varying a height of the variable portion varies a level of thermal engagement between the conductive portion of the reservoir and the heater plate, use of a humidifier reservoir base component with a maximum water capacity substantially equal to the predetermined maximum volume of water of the humidifier reservoir or the use of intersecting inlet and outlet axes.

Abstract: An integrated respiratory pressure therapy device and humidifier for pressurising and humidifying breathable air to treat a respiratory disorder in a patient, includes a blower configured to pressurise the breathable air; a water reservoir configured to hold a volume of water to be used for humidification of the breathable air, the water reservoir comprising a water reservoir base, a water reservoir lid connected to the water reservoir base, and a compliant portion. The compliant portion is constructed from an elastomeric material and configured to seal between the water reservoir base and the water reservoir lid. A water reservoir dock forms a cavity configured to partially receive the water reservoir. The water reservoir lid includes a protrusion and the water reservoir dock includes a recess configured to releasably engage one another to secure the water reservoir to the water reservoir dock.

Abstract: A treatment system includes a delivery device which delivers a combination of a breathing gas and frozen ice or other particles to a patient in order to induce hypothermia. The treatment system also includes a temperature system for measuring the temperature of exhaled gases and a controller which can adjust the duration or rate at which the ice particles are delivered in order to control the patient's core temperature based on the measured exhalation gas temperature.

Abstract: The present disclosure pertains to delivering sensory stimulation to a user during a sleep session. In some embodiments, sensors are configured to generate output signals conveying information related to brain activity of the user during the sleep session. Sensory stimulators are configured to provide the sensory stimulation to the user during the sleep session. One or more processors are configured to determine a demographic group for the user; select a stimulation parameter model associated with the demographic group of the user from a set of stimulation parameter models associated with different demographic groups; and control the one or more sensory stimulators to deliver the sensory stimulation to the user based on the stimulation parameter model for the demographic group of the user and the output signals.

Abstract: Systems, devices and methods for draining and analyzing bodily fluids are disclosed in which a drainage assembly is configured to prevent negative pressure build-up. The drainage assembly generally includes a catheter which may include a drainage lumen, a reservoir, a venting mechanism in fluid communication with the drainage lumen and a positive pressure lumen, and a controller. The venting mechanism may further include a valve which is configured to maintain a closed position, as well as a vent in fluid communication with the valve, where the venting mechanism is configured to inhibit wetting of the vent from fluid within the drainage lumen.

Abstract: A method of making a ready-to-use catheter assembly is provided, which can be immediately used by a patient. The ready-to-use catheter assembly ensures that the catheter does not suffer from a loss of quality during its shelf life and a wetting medium are provided. The method comprises: placing a catheter with an inactivated hydrophilic outer surface at least along its insertable length and a wetting medium in a catheter package; treating the catheter package with the catheter and the wetting medium with electro-magnetic and/or particle radiation while at least initially the hydrophilic outer surface at least along the insertable length of the catheter remains inactivated; and activating the hydrophilic outer surface at least along the insertable length of the catheter with the wetting medium during and/or after the radiation treatment and wherein the wetting medium decreases in viscosity when submitted to electro-magnetic and/or particle radiation.

Abstract: An apparatus and method are disclosed for providing feedback for a steerable medical device assembly for deflecting a device, the assembly comprising a control handle comprising an actuation mechanism. The assembly additionally comprises a device coupled to the control handle and operable to be deflected upon actuation of the actuation mechanism, and a feedback mechanism for providing an indication of the deflection of the device, wherein the feedback mechanism is associated with the actuation mechanism for deflecting the device.

Abstract: A medical apparatus according to one embodiment of the present invention can be used for dissociating adhesion to an epidural space and alleviating stenosis to a spinal canal; and comprises: an insertion part including a first end configured to be inserted into a human body and a second end opposite to the first end, and having a first through hole extended from the first end to the second end and formed inside the insertion part, an expansion part configured to be expandable and formed on an outer surface of the insertion part at a predetermined distance apart from the first end of the insertion part, a pair of wires extending in the insertion part and fixed to a region of the first end of the insertion part, a main body, a dial installed to the main body, and a rotation control part coupled to the dial.

Abstract: A fluid delivery system including a first balloon and a second balloon at least partially positioned within the first balloon, wherein the second balloon has an inner surface, an outer surface, and at least one micro-needle extending outwardly from the outer surface of the second balloon. The delivery system can further include a fluid source in communication with at least one of the micro-needles of the second balloon.

Abstract: A parison for being blow molded into a medical balloon for a catheter includes a first tubular layer having a functional modification and a second tubular layer adapted for bonding with the first tubular layer to form the blow molded balloon. Related methods are also disclosed.

Abstract: A method for forming a balloon provides a preform that encloses an internal space. The preform is pre-heated to a shaping temperature by passing a heated gas or fluid via an inlet of the preform into the internal space. The preform is then shaped the preform into a balloon. A device is configured to heat a preform using heated gas or fluid to decouple heating from the temperature of a shaping tool.

Abstract: Devices, assemblies, systems, and techniques described herein may deliver a pressure wave to structures of a heart, such an aortic valve. For example, a medical assembly may include an expandable member configured to expand from a collapsed configuration to an expanded configuration, the expandable member configured to at least partially define a channel through the expandable member in the expanded configuration and one or more electrodes carried by the expandable member. The one or more electrodes may be configured to transmit an electrical signal through a fluid to cause the fluid to undergo cavitation that generates a pressure wave within the fluid.

Abstract: Various systems and methods are provided for reducing pressure at an outflow of a duct, such as the thoracic duct or the lymphatic duct, for example, the right lymphatic duct. A catheter system can be configured to be at least partially implanted within a vein of a patient in the vicinity of an outflow port of a duct of the lymphatic system. The catheter system includes first and second selectively deployable restriction members each configured to be activated to at least partially occlude the vein within which the catheter is implanted and to thus restrict fluid within a portion of the vein. The catheter system includes an impeller configured to be driven by a motor to induce a low pressure zone between the restriction members by causing blood to be pumped through the catheter when the restriction members occlude the vein.

Abstract: Devices and methods for delivering substances to lung tissue through an extra-anatomic passage created in an airway.

Abstract: The invention relates to a connector (1) for connecting a catheter (2) to a fluid transfer system comprising a main body (11) with a tubular pin (111) adapted to be inserted into an end portion (21) of the catheter (2) such as to provide a fluid connection between the catheter (2) and the tubular pin (111). The connector (1) is characterized in that a fixing means (12) is movably connected to the main body (11), wherein the fixing means (11) is adapted to fix the catheter (2) to the connector (1) when the fixing means (12) is in a fixing position.

Abstract: A system and method is provided for applying an anti-pathogenic material to various surfaces of a medical device, wherein the method includes identifying various surfaces of the medical tests which include noncritical dimensions, and limiting the application of the anti-pathogenic material to those surfaces. Some aspects of the invention further include the application of an anti-pathogenic lubricant material to various parts or components of a medical device to reduce friction.