Patents Issued in July 14, 2022
  • Publication number: 20220218242
    Abstract: Disclosed herein are methods and apparatus for making a determination whether a blood sample is, or is not, infected with a malaria parasite. The determination is made using a trained machine-learning (ML) algorithm. In some aspects, a microfluidic chip is used for the concentration of red blood cells infected with these parasites from uninfected red blood cells, the staining of the blood sample which differentially stains infected and uninfected red blood cells, and holds the sample of interest for imaging. The microfluidic chip is inserted into an optical subsystem that magnifies the image created from transmitted light microscopy. The magnified image is captured with a camera, and a trained ML algorithm assesses if the sample does or does not contain the parasite. Generally, the ML algorithm is executed on a portable computing device such as a smartphone.
    Type: Application
    Filed: May 29, 2020
    Publication date: July 14, 2022
    Inventors: Vishwanath SUBRAMANIAM, Mark DREW, Jonathan KADOWAKI, Travis JONES, Joseph WEST, Marcel YOTEBIENG, Shaurya PRAKASH, Alexander SCARMUZZI, Redi LLAPI, Jack CROWLEY, Sandra METZLER
  • Publication number: 20220218243
    Abstract: A consumer electronic device and method for measuring the level of chlorophyll in a human subject. The device comprises a light source that exposes the subject to light to induce fluorescence of the chlorophyll, and a photometer that measures the level of fluorescing chlorophyll. The device may measure the level of chlorophyll without taking a blood or tissue sample, and may be a wearable device. The device may have at least one filter or surface that blocks light of undesired wavelengths or polarity, or selects light of desired wavelengths or polarity. The device may store, communicate, display or use the measured level of chlorophyll over a period of time.
    Type: Application
    Filed: March 28, 2022
    Publication date: July 14, 2022
    Inventor: Adam M. HASSE
  • Publication number: 20220218244
    Abstract: The present disclosure is directed to methods and systems for combining physiological data from a pulse oximeter coupled to a player playing a tennis match with match data corresponding to the tennis match. An example system can comprise an emitter configured to transmit optical radiation towards a tissue site of the player; a detector configured to detect light attenuated from the tissue site responsive to the transmitted optical radiation; and one or more hardware processors. The one or more hardware processors can be configured, via executable software instructions, to: receive physiological data responsive to the detected light, wherein the physiological data can include one or more physiological parameters including a pulse rate; receive match data corresponding to an occurrence in the tennis match; and generate a visual alert to one or more viewers of the tennis match based on a trigger event corresponding to the received physiological data and the match data.
    Type: Application
    Filed: January 10, 2022
    Publication date: July 14, 2022
    Inventors: Massi Joe E. Kiani, Bilal Muhsin
  • Publication number: 20220218245
    Abstract: A probe unit (30) of this optical measurement device (100) includes a base member (31) rotatable about a central axis (80), a light-transmitting probe (32) and a light-receiving probe (33) protruding in a first direction from the base member, and a plurality of pin members (34) for parting hairs, the plurality of pin members protruding in the first direction from the base member. The plurality of pin members is inclined obliquely at least either in a direction toward a central axis side of the base member or in a circumferential direction about the central axis of the base member.
    Type: Application
    Filed: December 23, 2019
    Publication date: July 14, 2022
    Inventors: Ayaka HORI, Shin NAKAMURA, Satoshi YOMOTA, Nobuyuki AKINAGA
  • Publication number: 20220218246
    Abstract: A direct electron transfer amperometric biosensor fabricated using direct write printing technology for in vivo electrochemical monitoring, such as monitoring of neurotransmitters and other biomarkers, e.g., in traumatic spinal cord injury. The biosensor is fabricated by immobilizing glutamate oxidase on nanocomposite electrodes made of platinum nanoparticles, multiwall carbon nanotubes and a conductive polymer on a flexible substrate.
    Type: Application
    Filed: July 6, 2020
    Publication date: July 14, 2022
    Inventors: Hyowon Lee, Tran N.H. Nguyen
  • Publication number: 20220218247
    Abstract: An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices. Embodiments include removing a substantially cylindrical cap from an inserter to expose a substantially cylindrical sleeve, removing a cover from a substantially cylindrical container holding sensor components, and fitting the sensor components into the inserter.
    Type: Application
    Filed: March 29, 2022
    Publication date: July 14, 2022
    Inventors: Manuel Luis Donnay, Tuan Nguyen, Louis G. Pace, Peter G. Robinson
  • Publication number: 20220218248
    Abstract: A bodily-fluid transfer device includes a housing, a pre-sample reservoir, and an actuator. The housing defines an inner volume between a substantially open proximal end portion and a distal end portion that includes a port couplable to a lumen-defining device. The pre-sample reservoir is fluidically couplable to the port to receive a first volume of bodily fluid. The actuator is at least partially disposed in the inner volume and has a proximal end portion that includes an engagement portion and a distal end portion that includes a sealing member. The engagement portion is configured to allow a user to selectively move the actuator between a first configuration such that bodily fluid can flow from the port to the pre-sample reservoir, and a second configuration such that bodily fluid can flow from the port to a sample reservoir defined at least in part by the sealing member and the housing.
    Type: Application
    Filed: March 31, 2022
    Publication date: July 14, 2022
    Applicant: Magnolia Medical Technologies, Inc.
    Inventors: Gregory J. BULLINGTON, Richard G. PATTON, Shan E. GAW
  • Publication number: 20220218249
    Abstract: A syringe-based device includes a housing, a pre-sample reservoir, and an actuator. The housing defines an inner volume between a substantially open proximal end portion and a distal end portion that includes a port couplable to a lumen-defining device. The pre-sample reservoir is fluidically couplable to the port to receive and isolate a first volume of bodily fluid. The actuator is at least partially disposed in the inner volume and has a proximal end portion that includes an engagement portion and a distal end portion that includes a sealing member. The engagement portion is configured to allow a user to selectively move the actuator between a first configuration such that bodily fluid can flow from the port to the pre-sample reservoir, and a second configuration such that bodily fluid can flow from the port to a sample reservoir defined at least in part by the sealing member and the housing.
    Type: Application
    Filed: March 31, 2022
    Publication date: July 14, 2022
    Applicant: Magnolia Medical Technologies, Inc.
    Inventors: Gregory J. BULLINGTON, Richard G. PATTON, Shan E. GAW
  • Publication number: 20220218250
    Abstract: A syringe-based device includes a housing, a pre-sample reservoir, and an actuator. The housing defines an inner volume between a substantially open proximal end portion and a distal end portion that includes a port couplable to a lumen-defining device. The pre-sample reservoir is fluidically couplable to the port to receive and isolate a first volume of bodily fluid. The actuator is at least partially disposed in the inner volume and has a proximal end portion that includes an engagement portion and a distal end portion that includes a sealing member. The engagement portion is configured to allow a user to selectively move the actuator between a first configuration such that bodily fluid can flow from the port to the pre-sample reservoir, and a second configuration such that bodily fluid can flow from the port to a sample reservoir defined at least in part by the sealing member and the housing.
    Type: Application
    Filed: March 31, 2022
    Publication date: July 14, 2022
    Applicant: Magnolia Medical Technologies, Inc.
    Inventors: Gregory J. BULLINGTON, Richard G. PATTON, Shan E. GAW
  • Publication number: 20220218251
    Abstract: Herein, systems and methods are disclosed including a sample acquisition component (SAC) for user-friendly sample collection, a separation component for optional separation of plasma, and one or more stabilization components for stabilizing analytes. In a particular embodiment, the system and methods are directed towards sample collection and stabilization with optional sample separation. Other embodiments can perform any combination of collection, separation, stabilization or detection.
    Type: Application
    Filed: January 21, 2022
    Publication date: July 14, 2022
    Inventors: Alicia Jackson, Rowan Chapman, Diana Maichin, Harry Glorikian
  • Publication number: 20220218252
    Abstract: A probe advancement device may be configured to couple to a catheter assembly. The probe advancement device may include a flexible housing, which may include a proximal end and a distal end. The probe advancement device may include a probe advancement element coupled to the proximal end of the flexible housing. The probe advancement element may include a probe extending in a distal direction within the flexible housing. The flexible housing may be configured to collapse along an axis in response to the probe being advanced in the distal direction. The probe may include a tube for blood collection, a guidewire, or another suitable element.
    Type: Application
    Filed: January 7, 2022
    Publication date: July 14, 2022
    Inventors: Curtis H. Blanchard, Adam J. Boud, Weston F. Harding
  • Publication number: 20220218253
    Abstract: The present invention relates to detecting impairment. Impairment is generally systemic and may impact all regions of the body, including muscle responses and cognitive responses. An inverse relationship typically exists between involuntary muscle reaction time to a stimulus and level of impairment. Reaction time is impacted by many intoxicants, as well as by one or more medical conditions. In preferred form, a video records an involuntary response to a stimulus such as a flash of light, a loud sound, touch or an electrical stimulation. Software is utilized to deliver the stimulus, acquire, analyze, and output the reaction time and/or magnitude of the subject. Classification of the degree of impairment is then determined, e.g., using of comparative datasets and/or algorithms.
    Type: Application
    Filed: January 12, 2021
    Publication date: July 14, 2022
    Inventor: Don P. SEIDENSPINNER
  • Publication number: 20220218254
    Abstract: The discovery of a new expression likely to be supported as a smell or taste expression by many users. An acquisition unit acquires appearance history of expressions used by a plurality of users from SNS server device via network. An extraction unit extracts, for each user attribute, appearing expression, appearance frequency of which exceeds threshold value on basis of appearance history acquired by the acquisition unit. The extracted appearing expression is referred to as a frequently appearing expression. A presentation unit presents the frequently appearing expression extracted by the extraction unit as an expression candidate meaning a smell to a user who uses an input device. A registration unit registers the smell and the expression in association with each other when the frequency of selection, by the user who uses the input device, of the expression presented to the user as an expression meaning the smell satisfies a determined condition.
    Type: Application
    Filed: March 24, 2020
    Publication date: July 14, 2022
    Applicant: JAPAN TOBACCO INC.
    Inventors: Toshiharu KURISU, Sayako SAKUMA, Yusuke OKAMURA, Yoshiyuki HABASHIMA
  • Publication number: 20220218255
    Abstract: A kit for regulating emotions and feelings by kids. The kit includes a main article that has avatars implemented to express different emotions, calming cards that include instructions to manage emotions by the kids, and calming articles that can be used by the kids to calm their emotions based on the instructions in the calming cards.
    Type: Application
    Filed: January 10, 2022
    Publication date: July 14, 2022
    Inventor: Danielle Jensen
  • Publication number: 20220218256
    Abstract: Systems and methods for a medical device are provided. The handheld medical device includes a housing including a front and rear side. A diaphragm is located in the center of the rear side of the housing. Three or less rear electrodes, configured to collect electromagnetic signals from the chest region of a patient, are located in a semi-circular in shape that encircles the diaphragm on the rear side of the housing. Two front electrodes located on the front side of the housing collect signals from the left and right index fingers of the patient. A screen is located between the two front electrodes. The device may include a transmitter, in some cases a Bluetooth module, for coupling the medical device to a user device. The user device includes an application that receives the signals and performs analysis on them. The five electrode inputs are used to calculate seven ECG channels.
    Type: Application
    Filed: January 6, 2022
    Publication date: July 14, 2022
    Inventor: Arvind Thiagarajan
  • Publication number: 20220218257
    Abstract: A method enables analysis of (e.g. bioelectric) signals acquired by measurement. The method provides N signals U for an observation space and each has a time- and space-dependent signal characteristic U. Digitized signals for a time period T have M time points and define an M×N matrix with M tuples of N signal values each. Signal values acquired at time t form an N-tuple ?t=(U1, . . . , UN)t in a signal space. The method acquires all combinations of k tuples from the M tuples, and calculates distances between all tuples. Distance values are calculated and define edge lengths of a (k?1) simplex (SIM) with one simplex assigned to each combination of k time points. Quantity characteristics of the simplex (SIM) are encoded into color values (COL), and displays the colors in a combinatorial time lattice (CTL). Each lattice point (GP) is displayed with the color encoded for the assigned simplex.
    Type: Application
    Filed: January 10, 2022
    Publication date: July 14, 2022
    Inventor: Oliver Hein
  • Publication number: 20220218258
    Abstract: An insertable cardiac monitor (ICM) with induction-based recharging capabilities and a transmitting coil for recharging the same are disclosed. The length of the monitoring performed by the ICM is extended and the functionality of the ICM enhanced, by including an internal energy harvesting module that allows for charging the ICM at a high speed without burning the patient or overheating components of the ICM. Internally, the energy harvesting module includes at least two overlapping receiving coils that are spaced to be orthogonal to each other and that have a tilt angle of substantially 45°. Such overlapping wire combination allows to minimize mutual inductance of the solenoid coils and increase the rate at which energy can be provided to the energy harvesting module. Further, the rate at which the energy is transmitted from the outside can be increased by defining in a transmitting coil a substantially triangular gap.
    Type: Application
    Filed: January 10, 2022
    Publication date: July 14, 2022
    Inventors: Jason Felix, Joshua Djon Green, Gust H. Bardy, Henry James Millican
  • Publication number: 20220218259
    Abstract: Systems and methods are provided for analyzing electrocardiogram (ECG) data of a patient using a substantial amount of ECG data. The systems receive ECG data from a sensing device positioned on a patient such as one or more ECG leads/electrodes that may be integrated in a smart device. The system may include an application that communicates with an ECG platform running on a server(s) that processes and analyzes the ECG data, e.g., using neural networks, to detect and/or predict various abnormalities, conditions and/or descriptors. The processed ECG data is used to generate a graphic user interface that is communicated from the server(s) to a computer for display in a user-friendly and interactive manner with enhanced accuracy. The systems may restrict access to certain ECG data, analyses, reports, and/or functionality to different entities, devices and/or users.
    Type: Application
    Filed: March 30, 2022
    Publication date: July 14, 2022
    Applicant: Cardiologs Technologies SAS
    Inventors: Johanna LAVERSIN, Baptiste Rios CAMPO, Chiara SCABELLONE, Anastasiya BODROVA, Benjamin BARRE, Gautier ZIMMERMAN, Wadii HAJJI, Benjamin GABERNIG, Delphine GERMAIN, Mathieu SORNAY, Romain POMIER, Marie-Auxille DENIS, Nathan SOUFFLET
  • Publication number: 20220218260
    Abstract: Disclosed herein are example methods and systems for predicting efficacy of pacemakers or cardiac resynchronization therapy (CRT) devices prior to implantation in patients based on electrocardiogram (ECG) heterogeneity analysis. A method of determining or predicting efficacy of implanting a pacemaker or cardiac resynchronization therapy (CRT) device in a patient includes receiving a first set of electrocardiogram (ECG) signals associated with the patients heart from spatially separated leads, analyzing data from the first set of ECG signals, quantifying a spatio-temporal heterogeneity of the first set of ECG signals based on the analysis, and determining or predicting efficacy of implanting the pacemaker or cardiac re-synchronization therapy (CRT) device in the patient based on the quantified spatio-temporal heterogeneity.
    Type: Application
    Filed: May 7, 2020
    Publication date: July 14, 2022
    Applicant: Beth Israel Deaconess Medical Center, Inc.
    Inventors: Richard L. VERRIER, Bruce D. Nearing, Peter J. ZIMETBAUM
  • Publication number: 20220218261
    Abstract: A method for processing time series data comprises: dividing time series data into a plurality of data fragments according to an objective function, the plurality of data fragments having a greatest similarity; in response to determining that at least one data fragment does not satisfy an iteration termination condition, performing following iteration operations on the at least one data fragment; and constructing a time series base pattern library by using a plurality of time series base patterns. The iteration operations includes: using the at least one data fragment as at least one update time series fragment; dividing each update time series fragment into a plurality of update data fragments; using each update data fragment that does not satisfy the iteration termination condition as a new update time series fragment; and using each update data fragment that satisfies the iteration termination condition as a time series base pattern.
    Type: Application
    Filed: September 28, 2020
    Publication date: July 14, 2022
    Inventors: Li JIANG, Yongyue SUN, Siyang LIANG, Meng WU, Yude LI, Hongyan LI, Litong HAN
  • Publication number: 20220218262
    Abstract: Techniques are disclosed for segmenting electrocardiogram (ECG) signals. In one example, a method to segment an electrocardiogram (ECG) signal may include detecting consecutive heartbeats in an ECG signal. The method also includes segmenting the ECG signal into multiple ECG segments surrounding the detected consecutive heartbeats and generating an ECG data set by joining consecutive ECG segments. The generated the ECG data set represents the detected heartbeats. In some such examples, each ECG segment is of a duration to include a QRS complex, a P wave, and a T wave.
    Type: Application
    Filed: April 22, 2020
    Publication date: July 14, 2022
    Inventor: Marek DZIUBINSKI
  • Publication number: 20220218263
    Abstract: A via visual representation a relationship between a smell or a taste of an object and a verbal description of the smell or taste, a display control unit controls a projector to display, in a display area including to a position of a sample, specified by the position specifying unit, one or more descriptions relating to the sense of smell or taste stimulated by the sample. Here, display control unit displays the descriptions by an appearance corresponding to the sample specified by the sample specifying unit.
    Type: Application
    Filed: March 24, 2020
    Publication date: July 14, 2022
    Inventors: Toshiharu KURISU, Sayako SAKUMA, Yusuke OKAMURA, Yoshiyuki HABASHIMA
  • Publication number: 20220218264
    Abstract: Methods and systems are disclosed for analyzing interactions between low-frequency oscillations and high-frequency activity in electromagnetic brain signals such as EEG, MEG, SEEG, and ECoG signals in subjects in real-time that does not depend on the signals being contained within narrow frequency bands, sinusoidal, sustained and monolithic. The disclosed methods and systems can be applied to electromagnetic brain signals to detect brain activity alterations associated with neurological and psychiatric diseases.
    Type: Application
    Filed: January 12, 2022
    Publication date: July 14, 2022
    Applicants: Washington University, Shanghai Jiao Tong University, Fudan University
    Inventors: Peter Brunner, Eric Leuthardt, Tao Xie, Zehan Wu, Xinjun Sheng, Liang Chen, Xiangyang Zhu
  • Publication number: 20220218265
    Abstract: Exemplary embodiments of the present disclosure provide for an integrated, flexible, implantable, optical neural interrogation apparatus, computer-accessible medium, system, and method for use thereof An integrated, flexible, fully-implantable, all-optical neural interrogation apparatus can include, e.g., a 2-dimensional (2D) planar array of optical photodetectors on an integrated electronic chip, the integrated electronic chip including control logic and image-capturing electronic circuitry, an amplitude or phase optical imaging mask for imaging, and a biocompatible packaging.
    Type: Application
    Filed: January 24, 2022
    Publication date: July 14, 2022
    Inventors: Kenneth L. SHEPARD, Sajjad MOAZENI, Eric POLLMANN
  • Publication number: 20220218266
    Abstract: To control a cognitive load to be given to the cognitive function of a user in rehabilitation, this invention provides a rehabilitation support apparatus including a detector that detects a three-dimensional rehabilitation action of the user, a display controller that generates, in a three-dimensional virtual space, an avatar object that moves in accordance with the detected rehabilitation action and a target object to be visually recognized by the user and displays these on a display, a notifier that notifies generation of the target object, and a cognitive load controller that gives a cognitive load to the user by generating the target object after an elapse of a predetermined time from the notification of the generation position of the target object.
    Type: Application
    Filed: March 25, 2021
    Publication date: July 14, 2022
    Applicant: mediVR, Inc.
    Inventor: Masahiko HARA
  • Publication number: 20220218267
    Abstract: An apparatus for earning out near-infrared spectroscopy using intensity-modulated near-infrared radiation or pulsed near-infrared radiation includes sources and detectors. For each source, there exists first and second distances. The first distance is a distance between the source and a first detector. The second distance is a distance between the source and the second detector. For each source, the difference between these two distances is the same. Additionally, wherein, for each source, the detector at a shorter distance is the same detector that is at a longer distance for the other source. A processor derives, from signals received by the detectors, a parameter indicative of two matched slopes. Tins parameter is either phase of the intensity-modulated near-infrared radiation or mean time-of-flight data for the pulsed near-infrared radiation. The processor then provides output data based on an average of the matched slopes.
    Type: Application
    Filed: June 12, 2020
    Publication date: July 14, 2022
    Inventors: Sergio Fantini, Angelo Sassaroli, Giles Blaney
  • Publication number: 20220218268
    Abstract: The present invention relates to an AI (Artificial Intelligence) based method for providing brain information comprising: a step 1 in which a brain signal obtaining portion of a brain signal measuring portion irradiates near-infrared ray to user's brain and detects light penetrating a cerebral cortex of the brain; a step 2 in which a brain signal processing portion of the brain signal measuring portion determines a level of oxygenation of hemoglobin in blood flow of the user's brain on the basis of the detected light; a step 3 in which a brain signal analyzing portion of the brain signal measuring portion extracts at least one brain activation area from a plurality of activated areas of the user's brain on the basis of the determined level of oxygenation of hemoglobin; and a step 4 in which a diagnosing portion determines a state of the user's brain on the basis of the at least one brain activation area extracted successively for a predetermined period of time, wherein a signal collecting operation of the bra
    Type: Application
    Filed: July 19, 2021
    Publication date: July 14, 2022
    Applicant: Actibrain Bio, Inc.
    Inventor: Sung Yeun Kim
  • Publication number: 20220218269
    Abstract: A method and computer programs for identifying time-frequency features of physiological events are disclosed. A computer system comprises filtering a set of physiological signals within each one of a plurality of time-frequency windows, obtaining a filtered set for each time-frequency window; calculating, for each time-frequency window, a given feature for the filtered set, each one of the signals of the filtered set having a given feature value, providing for each time-frequency window a set of feature values; and calculating, for each time-frequency window a first quantifier defined as a function of said set of features values and/or a second quantifier defined as a function of an empirical distribution of said set of feature values. The first quantifier can be compared with a first threshold and the second quantifier can be compared with a second threshold. The computing system can further select the time-frequency windows satisfying the first threshold and/or the second threshold.
    Type: Application
    Filed: May 26, 2020
    Publication date: July 14, 2022
    Applicant: Universitat Pompeu Fabra
    Inventors: Manel Vila Vidal, Adria Tauste Campo
  • Publication number: 20220218270
    Abstract: Method and system for estimating skin liquid levels, comprising acquiring a plurality of spectrally distinct images of a skin of a body part, and for each area out of a plurality of areas on the body part: obtaining, from the plurality of spectrally distinct images, corresponding spectrally distinct light levels of the area, acquiring an angular orientation of the area, and based on the spectrally distinct light levels and the angular orientation of the area, determining a skin liquid level for the area, and, based on the skin liquid level for each area, generating a skin liquid levels map for the body part indicative of the skid liquid levels of the plurality of areas on the body part.
    Type: Application
    Filed: September 2, 2021
    Publication date: July 14, 2022
    Inventors: Elior Dekel, Roni Dobrinsky
  • Publication number: 20220218271
    Abstract: In some aspects, a non-transitory computer readable medium is disclosed that has an application stored thereon that when executed by a processor of an electronic device causes the processor to perform a process. The process can include receiving motion data from a motion sensor, the motion data being indicative of motion by a user while wearing the motion sensor. The process can also include transmitting the motion data to a server, receiving from the server a time that the motion data indicates a foot of the user experienced a loading force which risked adversely impacting an existing foot ulcer or causing a new foot ulcer, determining a geographic location of the motion sensor at the time that the foot experienced the loading force, displaying the time and the geographic location, and requesting that the user identify an activity engaged in by the user at the time and the geographic location.
    Type: Application
    Filed: April 16, 2020
    Publication date: July 14, 2022
    Inventors: Jonathan Edward Mika Belding, Johannes Dagevos van Rij, Allan Kenneth Frazer Grugeon Hunt, Jonathon Simon Lay, Brian William Quist, Damian Lawson Smith
  • Publication number: 20220218272
    Abstract: Embodiments described herein generally relate to devices, methods and systems for determining differential blood oxygenation for early detection of pressure ulcers. By applying near infrared radiation of an appropriate wavelength to the tissue and determining the absorbance at a plurality of points where the distance between the source of the near infrared radiation and the detector are known, the oxygenation state of the hemoglobin can be determined based on position in a three-dimensional space.
    Type: Application
    Filed: May 29, 2020
    Publication date: July 14, 2022
    Applicants: University of Houston System, Apogee Interests, LLC, The Methodist Hospital
    Inventors: Luca POLLONINI, Scott E. PARZYNSKI, Jeffrey D. FRIEDMAN
  • Publication number: 20220218273
    Abstract: A system and method for noninvasive sleep monitoring are disclosed. The system includes an in-ear biosensor system (“biosensor system”) and a data analysis system. The biosensor system includes at least one earbud placed at or within an ear canal of an individual. The earbud includes an acoustic sensor that detects biosignals including infrasonic and audible signals from the individual in the ear canal. A controller board of the biosensor system collects and forwards the biosignals to the data analysis system. The data analysis system analyzes the biosignals to identify and monitor physiological information of the individual during sleep. The physiological information includes sleep stages, sleeping position information, sleep events including snore, breathing cessation and bruxism events, and sleep disorders, in examples. The system can also induce changes to the physiological information during sleep using external stimuli to improve a quality of sleep.
    Type: Application
    Filed: January 13, 2022
    Publication date: July 14, 2022
    Inventors: Anna Barnacka, Karlen Shahinyan
  • Publication number: 20220218274
    Abstract: A method of predicting the likelihood of responding to one or more obstructive sleep apnea (OSA) treatments for obstructive sleep apnea (OSA) of a candidate subject, the method including the steps of: (a) measuring a first series of polysomnography and anthropometric parameters for at least a collection of OSA sufferers; (b) correlating the parameters with at least one of the corresponding upper-airway collapsibility (Pcrit), arousal threshold, loop gain and pharyngeal muscle responsiveness measurement of each subject; (c) determining a corresponding description structure describing the correlation of step (d); and (d) utilising the corresponding description structure, in conjunction with a series of polysomnography and anthropometric parameters measured for the candidate subject to predict the likelihood of responding to one or more obstructive sleep apnea (OSA) treatments to thereby provide a clinical decision diagnostic tool for obstructive sleep apnea.
    Type: Application
    Filed: May 22, 2020
    Publication date: July 14, 2022
    Inventors: Danny J. Eckert, Ritaban Dutta
  • Publication number: 20220218275
    Abstract: A physiological information processing apparatus includes a processor and a memory configured to store a computer readable command. The computer readable command is executed by the processor, the physiological information processing apparatus is configured to acquire physiological information data of a subject to which an anesthetic is administered, specify, based on the physiological information data, at least one of an appropriate management time, which is a time during which anesthesia management is appropriately performed on the subject, and an inappropriate management time, which is a time during which the anesthesia management is not appropriately performed, calculate an anesthesia management evaluation index, which is an evaluation index for the anesthesia. management, based on the at least one of the inappropriate management time and the appropriate management time and an operation time of the subject, and output the calculated anesthesia management evaluation index.
    Type: Application
    Filed: March 26, 2021
    Publication date: July 14, 2022
    Applicant: NIHON KOHDEN CORPORATION
    Inventors: Yoshinori MURAYAMA, Osamu NAGATA
  • Publication number: 20220218276
    Abstract: A data collecting device including a microcontroller communicatively coupled to at least one of a plurality of sensors, the sensors being configured to detect vital signs of a patient including at least one of temperature, blood oxygen saturation level, blood pressure, and a level of carbon dioxide exhaled by the patient, the microcontroller being configured to, in response to receiving data from at least one of the sensors, perform noise filtering and aggregate the received sensor data into a plurality of data packets, and transmit the filtered and aggregated data to portable mobile computing device communicatively coupled thereto.
    Type: Application
    Filed: January 7, 2022
    Publication date: July 14, 2022
    Inventors: Paul BARTON, James F. Anderson
  • Publication number: 20220218277
    Abstract: A system for remote transdermal alcohol monitoring includes and/or interfaces with a transdermal alcohol sensing device. Additionally or alternatively, the system can include and/or interface with any or all of: a user device; a supplementary alcohol sensing device; a set of supplementary sensors; a computing subsystem; a user interface; and/or any other components. A method for remote transdermal alcohol monitoring includes: receiving a set of inputs; determining a set of outputs; and triggering an action based on the set of outputs.
    Type: Application
    Filed: January 12, 2022
    Publication date: July 14, 2022
    Inventor: Keith Harry Nothacker
  • Publication number: 20220218278
    Abstract: A method includes applying a plurality of electrical stimuli having differing amplitudes at a first position in a brain of a patient. The method further includes, for each of the plurality of electrical stimuli, detecting a resonant response from a target neural structure in the brain, each resonant response evoked by a respective one of the electrical stimuli. The method also includes determining a change in one or more common waveform characteristics between two or more of the detected resonant responses and determining an effectiveness in delivering therapeutic stimulation at the first position based on the change.
    Type: Application
    Filed: August 5, 2020
    Publication date: July 14, 2022
    Inventors: Nicholas Sinclair, Hugh McDermott, Arthur Wesley Thevathasan, Kristian Bulluss, James Fallon
  • Publication number: 20220218279
    Abstract: A photoplethysmography sensor is provided. The sensor includes a housing, a cover plate, an optical device configured to emit light outwards, and a photoelectric sensor configured to receive an external optical signal. The housing and the cover plate form an enclosed space, and the optical device and the photoelectric sensor are accommodated in the enclosed space. The cover plate includes a first area used by the optical device to emit the light outwards and a second area used by the photoelectric sensor to receive the external optical signal. The cover plate further includes a third area and a shielding structure disposed on the third area, and the shielding structure is configured to isolate light between the optical device and the photoelectric sensor. The shielding structure is disposed in the third area so that isolation between the optical device and the photoelectric sensor is improved.
    Type: Application
    Filed: June 17, 2020
    Publication date: July 14, 2022
    Applicant: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Rongguang YANG, Yi XI, Shiyou SUN, Zhi GUO, Bin ZHANG
  • Publication number: 20220218280
    Abstract: A biological information monitoring system includes: a biological information monitoring apparatus that monitors biological information of an organism wearing the biological information monitoring apparatus on an ear.
    Type: Application
    Filed: March 30, 2022
    Publication date: July 14, 2022
    Applicant: Agama-X Co., Ltd.
    Inventors: Motofumi BABA, Masahiro SATO, Kiichiro ARIKAWA, Tadashi SUTO, Kengo TOKUCHI
  • Publication number: 20220218281
    Abstract: A hearing aid having one or more biometrical sensors, where the hearing aid comprises at least one microphone configured to receive a sound of the surroundings, a signal processor configured to process the sound received from the microphone and a speaker unit configuration configured to emit the processed sound into the ear of a user, wherein one or more sensors is positioned substantially in the ear together with at least a part of the hearing aid, wherein the one or more sensors is configured as biometrical sensors configured for recording health data of a hearing aid user.
    Type: Application
    Filed: January 7, 2022
    Publication date: July 14, 2022
    Applicant: Oticon A/S
    Inventors: Svend Oscar PETERSEN, Mathias Bruun LARSEN, Sergi Rotger GRIFUL, José Antonio ESPARZA ISASA, Mikkel NIELSEN, Kim Mølholm HEJLESEN, Henrik BENDSEN, Preben KVIST, Svend Erik ELGAARD, Jeanette Bülow NIELSEN, Zenia Holtzmann LAUSTEN, Malte KIEWNING, Jesper B. JOHANSEN, Nicolai WESTERGREN, Tanveer BHUIYAN, Sudershan Y.S
  • Publication number: 20220218282
    Abstract: There is provided an apparatus for positioning a front sensor and/or a back sensor across a thorax of a target individual, the apparatus comprising: a back positioning element comprising: a collar sized and shaped for fitting to a shoulder line and base of a back of a neck of the target individual, and an elongated element having a first end region connected to the collar, and a second end region with a location marker set to correspond to a target anatomical feature of the spine of the target individual, wherein when in use, the elongated element is positioned parallel to and over a long axis of a spine on the back of the target individual, and at least one front sensor and at least one back sensor are positioned on the thorax of the patient relative to the back positioning element for transmitting to and/or sensing from the target region.
    Type: Application
    Filed: May 20, 2020
    Publication date: July 14, 2022
    Applicant: Sensible Medical Innovations Ltd.
    Inventors: Amir SAROKA, Anat SHANI, Shlomi BERGIDA, Liran MISHANI, Naama BERGMAN, Arin MAZRI, Nadav MIZRAHI, Viki YELENSKI, Shay YULZARY
  • Publication number: 20220218283
    Abstract: A holder for a medical device has a transcutaneously insertable portion and at least one housing. The holder has at least one mounting device that has a first side and an opposing second side. The mounting device also has a hole reaching from the first side to the second side. The mounting device is configured for being connected to the housing of the medical device. The holder also has two straps that are respectively attached to the mounting device and are fixedly connectable to each other.
    Type: Application
    Filed: March 30, 2022
    Publication date: July 14, 2022
    Inventors: Hans List, Frederic Wehowski
  • Publication number: 20220218284
    Abstract: A sensor cartridge according to embodiments of the disclosure is capable of being used with a non-invasive physiological sensor. Certain embodiments of the sensor cartridge protect the sensor from damage, such as damage due to repeated use, reduce the need for sensor sanitization, or both. Further, embodiments of the sensor cartridge are positionable on the user before insertion in the sensor and allow for improved alignment of the treatment site with the sensor. In addition, the sensor cartridge of certain embodiments of the disclosure can be configured to allow a single sensor to comfortably accommodate treatment sites of various sizes such as for both adult and pediatric applications.
    Type: Application
    Filed: March 29, 2022
    Publication date: July 14, 2022
    Inventors: Ammar Al-Ali, Marcelo Lamego, Jim Litchfield, Gregory A. Olsen
  • Publication number: 20220218285
    Abstract: A toothbrush having a physiological sensing function, comprising a grip part, a head part, and a sensing module. The grip part has an inner space as well as a top end and a tail end opposite to each other in a length direction. The head part is provided at the top end of the grip part. The grip part is further provided with a sensing region. The sensing module is provided in the inner space of the grip part and disposed corresponding to the sensing region. The sensing module executes a physiological sensing function in the sensing region, and generates physiological sensing information. When a user holds the toothbrush to brush teeth, a finger pulp or palm of the user presses on the sensing region, and thus the sensing module can execute the physiological sensing function by means of the sensing region and generate physiological sensing information, so that the user can understand his/her own health information more comprehensively.
    Type: Application
    Filed: May 28, 2019
    Publication date: July 14, 2022
    Inventor: Shou-Jen Huang
  • Publication number: 20220218286
    Abstract: Apparatus, system and method for medical analysis of a seated individual, includes determining the aortic valve opening; the PTT; and calculating the PWV. Determining the aortic valve opening includes collecting BCG data while sitting on a seat and determining the timing of the aortic valve opening, taking into account posture. Measuring the aortic pulse wave transit time includes collecting BCG data while sitting on a seat capable of measuring changes in apparent weight; determining the timing of the aortic valve opening; detecting the arrival of the pulse wave at the end point; and measuring the relative timings of the two events. Calculating the PWV includes determining a length of the arterial segment through which a pulse wave is to be measured between a start point and an end point; and dividing the determined length of the arterial segment by the PTT.
    Type: Application
    Filed: December 21, 2021
    Publication date: July 14, 2022
    Applicant: Rochester Institute of Technology
    Inventors: David A. Borkholder, Nicholas J. Conn
  • Publication number: 20220218287
    Abstract: Provided are a disease-condition assessment device for assessing a disease condition of a subject, a disease-condition assessment method, a program for disease-condition assessment device, and a disease-condition assessment system. The disease condition assessment device acquires a data of a seat pressure distribution on a seating surface where a subject operating a vehicle is seated, calculates a center position depending on the seat pressure distribution, calculates a degree of laterality in the seat pressure distribution based on the center position, and assesses a disease condition of the subject depending on the degree of laterality.
    Type: Application
    Filed: February 28, 2020
    Publication date: July 14, 2022
    Inventors: Hidehiko KOMINE, Satoshi KITAZAKI, Motoyuki AKAMATSU, Kei ISHII, Hideo TSURUSHIMA, Motoki SHINO
  • Publication number: 20220218288
    Abstract: Provided are a signal adjustment method for a PPG apparatus and a PPG apparatus. The method comprises: when background light data or actual effective light data does not meet a preset background light data range or a preset first effective light data range, performing a dimming operation comprising: determining an estimated current transfer ratio; estimating a driving current required by a light source and a gain required by an analog front end; calculating estimated effective light data of a PPG apparatus according to the estimated driving current required by the light source, the gain required by the analog front end, and the estimated current transfer ratio; when the estimated effective light data meets a preset second effective light data range, generating a to-be-adjusted current/gain value according to the estimated driving current required by the light source and the gain required by the analog front end.
    Type: Application
    Filed: March 31, 2022
    Publication date: July 14, 2022
    Inventors: Liangshou CHEN, Saiwen LU
  • Publication number: 20220218289
    Abstract: Apparatuses and methods are provided to predict or diagnose an ischemic event, such as a stroke or a transient ischemic attack (TIA). A machine-learning model such as a neural network is generated that allows for recognition of an ECG consistent with an ischemic event. A system is trained and used to process a recording of ECG data from a patient to generate a prediction indicating a likelihood that the patient will experience a stroke. In other examples, a system is trained and used to process a recording of ECG data from a patient and detect an ischemic event for the patient who did not appear to have such an ischemic event.
    Type: Application
    Filed: March 31, 2022
    Publication date: July 14, 2022
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Itzhak Zachi Attia, Paul A. Friedman, Samuel J. Asirvatham, Peter A. Noseworthy, Suraj Kapa, Francisco Lopez-Jimenez
  • Publication number: 20220218290
    Abstract: Systems and methods configured to provide asthma-related information of subjects based on environmental conditions and/or subject condition information are disclosed. Exemplary implementations may: obtain location information related to a physical location of a subject over time; obtain, based on the location information, environmental conditions at or around the physical location indicated by the location information; obtain subject condition information defining remote diagnostic information and subject health information; and effectuate presentation of a graphical user interface that conveys the subject condition information.
    Type: Application
    Filed: January 13, 2021
    Publication date: July 14, 2022
    Inventor: Jemal Dean Zikria
  • Publication number: 20220218291
    Abstract: An optical based patient monitoring system employing an optical sensor and providing an indication of an optical change which does not correlate to a change in a physiological blood parameter and based on that indication, providing a care provider an indication of a condition of a patient. The optical based patient monitoring system providing the indication of the patient condition in relation to a patient using an IV setup.
    Type: Application
    Filed: January 21, 2022
    Publication date: July 14, 2022
    Inventors: Ammar Al-Ali, John Graybeal, Massi Joe E. Kiani, Michael Petterson, Chris Kilpatrick