Abstract: Systems and method for multiplexing and alternating light of different wavelengths in an ophthalmoscope are disclosed herein. According to an aspect, an imaging system includes an illumination system configured to generate and output light that alternates between at least two different wavelengths. The imaging system includes a multiplexer configured to receive the output light and to multiplex the light of different wavelengths onto a single optical channel. Further, the imaging system includes a scanning laser ophthalmoscope probe configured to operatively receive the multiplexed light, to apply the multiplexed light to a subject for imaging, and to receive light returning from the subject for generating an image of the subject.

Abstract: A multi-sensor system (100) having a plurality of dental sensors (101-S; 101-M) for arrangement in an oral cavity, including at least one slave dental sensor (101-S) for acquiring measurement data in an oral cavity with a transmitting device (103) for transmitting the measurement data; and a master dental sensor (101-M) with a receiving device (109-M) for receiving the measurement data from the slave dental sensor (101-S).

Abstract: A telemedicine system with dynamic imaging is disclosed herein. In some embodiments, the telemedicine system comprises a laser imaging and treatment apparatus, and associated systems and methods that allow a physician (e.g., a surgeon) to perform laser surgical procedures on an eye structure or a body surface with a laser imaging and treatment apparatus disposed at a first (i.e. local) location from a control system disposed at a second (i.e. remote) location, e.g., a physician's office. Also, in some embodiments, communication between the laser imaging and treatment apparatus and control system is achieved via the Internet®. Further, in some embodiments, the telemedicine system includes a dynamic imaging system and/or a facial recognition system that verifies the identity of a patient, and is capable of being used for other important applications, such as tracking and analyzing trends in a disease process.

Abstract: An instrument for internal mapping includes a flexible elongated portion (702) and an expandable portion (710) coupled distally to the elongated portion, the expandable portion having one or more expandable loops. An array of sensors (706) and electrodes (708) is distributed on the expandable portion and is configured to concurrently register the instrument to real-time images of an anatomy using the sensors and measure electrical characteristics of the anatomy with the electrodes to generate an electro-physiology (EP) map having the anatomy and intensities of the electrical characteristics mapped together in the real-time images.

Abstract: A palpation support device according to an embodiment includes: a palpation data acquiring part configured to acquire a palpation data based on a plurality of pressure values applied to fingers of an examiner; and a diagnosis support information output part configured to output diagnosis support information based on the palpation data.

Abstract: Systems and methods for multi-modal imaging using an endoscope having an instrument channel, where the imaging is achieved without using the channel, are disclosed. The systems can include a multi-modal imaging paddle housing couple to a distal end of the endoscope. The housing can receive at least two imaging probes. The imaging probes can be an angle-resolved low-coherence interferometry probe (a/LCI) and an optical coherence tomography (OCT) probe. The housing can be scaled and positioned to be visible via the endoscope camera. The system and method can include locating the housing in a region of interest using the endoscope camera, acquiring OCT measurements to identify targets, and then acquiring a/LCI measurements at the identified targets.

Abstract: Certain aspects relate to apparatuses and techniques for non-invasive and non-contact optical imaging that acquires a plurality of images corresponding to both different times and different frequencies. Additionally, alternatives described herein are used with a variety of tissue classification applications including assessing the presence and severity of tissue conditions, such as necrosis and small vessel disease, at a potential or determined amputation site.

Abstract: A non-invasive, transcutaneous, real-time viral detection device that is configured for self-administration, e.g., at a user's home. In one embodiment, and after positioning the device relative to the human body part (e.g., the user's finger), light sources in the device are activated (excited), and resulting data captured. In particular, a set of Raman spectra are collected from a configured set of emitters and detectors in the device and delivered to a nearby receiver, preferably wirelessly. The receiver filters and de-convolves the Raman spectra producing a data set representative of the constituent elements in the user's tissue of interest. The data set is applied against a statistical classifier, e.g., a neural network that has been trained to recognize and distinguish the absence or presence of viral components, e.g., C-19, or its associated blood-borne acute phase reactants.

Abstract: Disclosed are methods and apparatuses for microvascular system imaging. In some embodiments, an apparatus for microvascular system imaging is a probe including at least one high-resolution image sensor module, at least one lens set, one or more optical filters, an illumination source, and a housing. In some embodiments, the lens set may be a miniature lens set. In some embodiments, the housing may be a tube structure. In some embodiments, the tube may be covered with a protective and/or sterile cover. The cover may be optically non-distorting. The imaging probe may additionally include a removable cap.

Abstract: An imaging system, device, and method for diagnosing tissue is provided. The system may include one or more light sources (e.g., LEDs) configured to project light in a plurality of wavelengths. A time-of-flight module may be configured to project a modulated light, receive a reflected portion of the modulated light, and/or generate a three-dimensional time-of-flight image based on the received reflected portion of the modulated light. A multispectral camera may be configured to receive a reflected portion of the light and generate a multispectral image based on the received reflected portion of the light. A processor may be configured to identify the time-of-flight image and the multispectral image; generate a data matrix based on combining one or more portions of the time-of-flight image and the multispectral image; and cause the data matrix to be displayed as a three-dimensional image.

Abstract: Temperature detection systems and methods for detecting temperature of an object are provided. The system utilizes either a predetermined temperature reference by using a well-behaved and calibrated thermal camera with reliable internal temperature reference calibration or one or more calibrated temperature reference devices, such as a blackbody reference, in view of the camera. The system then determines temperature values for each pixel within the image based on mean and median reference temperatures determined from the predetermined temperature reference or the calibrated temperature reference devices and identifies any pixels in the image having a predetermined characteristics, such as those pixels having a temperature greater than the predetermined reference temperature or some other threshold, or, alternatively, pixels in a range of temperatures.

Abstract: A temperature measurement probe for a patient is provided. The probe includes a sensor assembly and produces a temperature map comprising temperature information for multiple patient locations.

Abstract: An estimation apparatus (30) includes a first estimation unit (31) configured to estimate a first pulse rate from a first video data which is captured a body part and output a first feature data derived based on the first video data; a training unit (32) configured to train a determination model to determine a confidence value which indicates an reliability in the estimation of the first pulse rate and a physiological information measured from the body; an acquiring unit (33) configured to acquire a second feature data derived by the first estimation unit, and acquire the confidence value of the second pulse rate using the second feature data and the determination model trained by the training unit; and a second estimation unit (34) configured to estimate a third pulse rate based on the acquired confidence value.

Abstract: Methods and systems for non-contact monitoring of a patient to determine cardiac information about the patient, for example, heart rate or pulse. The methods and systems can additionally monitor respiratory parameters if desired. The methods and systems of this disclosure utilize light intensity of reflected features (e.g., IR, UV, RBG, or other light) to determine the cardiac parameter and can also utilize the light intensity of reflected features to determine the respiratory parameter. The same or a different respirator parameter can be determined by depth (distance) information.

Abstract: Methods and systems are provided for estimating velocity of blood, flowing along a blood vessel at a blood flow direction, based on measurements made using a medical implement that resided in a portion of the blood vessel and comprised a first electrode and a second electrode. One of the disclosed methods include: accessing voltage measurements measured at the first and second electrodes when a bolus of a fluid went through the portion of the blood vessel at the blood flow direction; wherein the voltage measurements were made at the first and the second electrodes; estimating a time that took the bolus to go from the first electrode to the second electrode based on the accessed voltage measurements; and estimating the velocity of the blood based on the estimated time and a distance known to exist along the medical implement between the first and second electrodes.

Abstract: Systems and methods are described relating to fluid volume sensing in the inferior vena cava (IVC) to obtain data from which information on fluid status, congestion and cardiac output may be derived.

Abstract: A detection system and a detection method and a sensing device for detecting stenosis of carotid artery are provided. The invention detection system for detecting a stenosis of a carotid artery includes a sensing device and a server. The sensing device includes a microphone. The microphone receives a frequency spectrum signal from a first location. There is a first distance between the first location and a second location of at least one of a plaque and a thrombus in the carotid artery. The first location is located on an extended path of the carotid artery. The server receives the frequency spectrum signal and calculates a stenosis percentage of the carotid artery corresponding to the frequency spectrum signal through a machine learning module and transmits the stenosis percentage to the sensing device.

Abstract: Provided is a technology that enables information display to be easily understandable to a user. A measurement device according to an aspect of the present invention includes a measurement unit configured to perform measurement of biological information, a first display unit configured to display a result of the measurement performed by the measurement unit, an installation unit configured to install an information terminal on the installation unit, the information terminal including a second display unit configured to display the result of the measurement, a communication unit configured to directly communicate with the information terminal installed on the installation unit, and a control unit configured to, while the information terminal is installed on the installation unit, cause the result of the measurement to be transmitted from the communication unit to the information terminal to cause the second display unit to display the result of the measurement.

Abstract: A sphygmomanometer includes a storage unit that stores a measured blood pressure value. In a nighttime blood pressure measurement mode, blood pressure measurement is automatically started according to a schedule, and a blood pressure is measured when a blood pressure measuring cuff is in a pressurization process or a depressurization process. Further, it is determined whether or not a current blood pressure value measured is different from a past blood pressure value stored in the storage unit beyond an allowable range. When the current blood pressure value is different from the past blood pressure value beyond the allowable range, it is discriminated which phenomenon among a plurality of predetermined types of phenomena has occurred in the subject. A time of remeasurement with respect to a measurement time of the current blood pressure value is variably set according to which phenomenon among the plurality of types of phenomena has occurred.

Abstract: A system (CV stenosis system) and method for noninvasive cardiac stenosis monitoring, diagnosis, analysis and reporting are disclosed. The CV stenosis system includes an in-ear biosensor system and a data analysis system. The in-ear biosensor system includes at least one earbud placed at or within an ear canal of an individual, where the at least one earbud includes one or more acoustic/vibration sensors that operate in both infrasonic and audible frequency ranges and detect biosignals from the individual. The data analysis system receives the biosignals from the biosensor system, separates the biosignals into components including infrasonic cardiac signals, and determines a type and level/severity of cardiovascular stenosis of the individual based upon the biosignals. In embodiments, the CV stenosis system can detect aortic stenosis and determine its severity, and detect stenoses of the left and right carotid arteries.

Abstract: A method for predicting a dynamic filling parameter for a heart-vessel system of a patient includes receiving electrocardiogram data for the patient over time, receiving data related to a respiratory cycle of the patient over time, and receiving continuous blood pressure data respectively continuous stroke volume data for the patient over time. The method also involves correlating the electrocardiogram data related to the respiratory cycle and the continuous blood pressure data respectively continuous stroke volume data thereby expressing the pulse pressure respectively stroke volume as a deconvolution of at least a function of the electrocardiogram data and a function of the respiratory cycle data. The method includes determining a value for a dynamic filling parameter representative for the hemodynamics of the patient based on the expression for the pulse pressure respectively stroke volume.

Abstract: The present disclosure relates to a concept for providing a score indicative of a physiological condition of at least one individual. The concept include measuring physiological or behavioral data of the individual, determining contextual data comprising a measurement context and/or socio-demographic features associated with the individual determining a metric based on the measured physiological or behavioral data, and determining the score by comparing the metric against a predicted value from a prediction model trained with the contextual data.

Abstract: A blood flow analysis device according to the present invention detects blood flow distribution by using a visible light image, compares blood flows between different measurement regions by using the blood flow distribution, and analyzes a correlation between blood flows simultaneously generated in different measurement regions.

Abstract: Wireless, variable inductance and resonant circuit-based vascular monitoring devices, systems, methodologies, and techniques, including specifically configured anchoring structures for same, are disclosed that can be used to assist healthcare professionals in predicting, preventing, and diagnosing various heart-related and other health conditions.

Abstract: A plethysmograph variability processor inputs a plethysmograph waveform having pulses corresponding to pulsatile blood flow within a tissue site. The processor derives plethysmograph values based upon selected plethysmograph features, determines variability values, and calculates a plethysmograph variability parameter. The variability values indicate the variability of the plethysmograph features. The plethysmograph variability parameter is representative of the variability values and provides a useful indication of various physiological conditions and the efficacy of treatment for those conditions.

Abstract: A system provides blood pressure monitoring for a user. The system includes an in-ear device, a sensor, and a processor. The in-ear device includes in-ear electrodes that capture electrical signals of pulses of a user's heartbeat from within an ear canal of the user. The sensor captures sensor data indicating tissue movements caused by the user's heartbeat. The processor determines a time interval between a peak in an R wave in electrocardiogram (EKG) data generated using the electrical signals and a peak in a waveform representing the tissue movement generated using the sensor data. The processor determines a blood pressure level of the user using the time interval. The sensor may be located on the in-ear device, and may be a motion sensor, an acoustic sensor, or a photoplethysmogram (PPG) sensor.

Abstract: Embodiments are directed to a blood pressure measurement device that includes a strap configured to couple the blood pressure measurement device to a user, an air pump coupled to the strap and having a housing defining a surface facing the user, and an inflatable chamber positioned on the surface of the air pump and fluidly coupled to the air pump. The inflatable chamber can be positioned between the air pump and the user when the blood pressure measurement device is worn by the user and expand towards the user when inflated. The blood pressure measurement device can also include a pressure sensing chamber coupled to the inflatable chamber and positioned between the inflatable chamber and the user when the blood pressure measurement device is worn by the user. The pressure sensing chamber can include a liquid volume and a pressure sensing device configured to detect a pressure of the liquid volume.

Abstract: Non-invasive measurement of intracranial pressure (ICP), for example mean ICP. A probe adjacent the head emits energy, such as ultrasound, and receives reflected signals. A processing unit derives ICP waveform from the signals. A pressure mechanism applies external pressure intermittently to outer surface of the head and incrementally increases the external pressure. The processing unit is configured to detect a decrease in amplitude of the ICP waveform (occurring in some embodiments only after an intermediate period of ICRS compensation), the processing unit configured to determine the ICP of the person from a sum of applied external pressures from a time of the initial value A1 until a final value at which the amplitude remains stable with additional increase in applied external pressure. In some cases, the final value is earlier than that but the processing unit extrapolates the sum to when the amplitude remains stable with additional increases in pressure.

Abstract: To provide a technique of stably obtaining quantitative parameter maps by preventing influences of artifacts caused by flow or body motion when calculated images with a plurality of parameters are generated at the same time. When a calculated image of a subject parameter or an apparatus parameter is generated by using a plurality of images obtained by performing imaging under different imaging conditions, an imaging condition under which the artifacts are easy to occur is examined in advance, and an imaging parameter set for quantitative parameter map calculation is optimized by excluding the imaging condition under which the artifact is easy to occur.

Abstract: A technique for determining skin sodium content using bioimpedance spectroscopy includes applying a current at a predetermined frequency to skin of a subject, measuring a voltage across the skin of the subject produced by the current, determining a resistance across the skin of the subject at the predetermined frequency using the measured voltage, and determining skin sodium content using the measured voltage.

Abstract: Systems and methods for evaluating neuromodulation via hemodynamic responses are disclosed herein. A system configured in accordance with embodiments of the present technology can include, for example, a neuromodulation catheter comprising an elongated shaft having a distal portion, and a plurality of electrodes spaced along a distal portion. The system can further include a controller communicatively coupled to the electrodes. The controller can be configured to apply first and second stimuli at and/or proximate to a target site within a blood vessel before and after delivering neuromodulation energy to the target site, and detect, via at least one of the electrodes, vessel impedance resulting from the first and second stimuli to determine a baseline impedance and a post-neuromodulation impedance. The controller can further be configured to assess the efficacy of the neuromodulation based, at least in part, on a comparison of the baseline impedance and the post-neuromodulation impedance.

Abstract: An electrochemical method and an electrochemical sensor for breath analysis of single or multiple analytes using a porous, preferably flexible and disposable supporting material is provided, a salt is incorporated, and which can be wetted in contact with the exhaled breath condensate. The electrochemical method acting simultaneously as sampling method, as an electrolyte and as a support for the electrode structures. In some embodiments the salt may be hygroscopic, such that the porous substrate stays wet. To ensure that the obtained signal originates from the analyte, the electrochemical sensor preferably exhibits a differential electrode design, including a sensing (analyte-sensitive) and a blank (analyte-insensitive) electrode in order to isolate and remove the background signals.

Abstract: An energy harvesting device includes a housing (2), a moveable device (12) disposed within the housing and including a first surface including a first material (15) and a second surface including a second material (17), wherein the moveable device is operable to move to bring the first and second surfaces together and apart to cause contact and separation between the first and second materials, a first strap (4) attached to the housing, a second strap (6) coupled to the moveable device, wherein movement of the second strap causes operation of the moveable device, and electronic circuitry (20) structured to harvest energy from the electrical charge generated by the contact between the first and second materials.

Abstract: Provided is an information processing device including an acquisition unit configured to acquire first load information measured by a first load measurement device provided on a sole of a user and second load information measured by a second load measurement device provided between a toe of the sole and the first load measurement device and a feature amount extracting unit configured to extract a feature amount used for identifying the user based on the first load information and the second load information.

Abstract: The disclosure provides a sensor element for detecting a force between a foot and a supporting surface.

Abstract: Provided is an information processing device including an acquisition unit configured to acquire load information based on a load applied to a load measurement device from a sole of a user and a feature amount extracting unit configured to extract a feature amount indicating a walking environment from time series data in at least one walking cycle included in the load information.

Abstract: A step width measurement device includes a distance calculation unit that calculates a distance between both feet of a user by using propagation data related to transmission/reception times of ultrasonic waves transmitted/received by ultrasonic transmission/reception devices mounted on each of the both feet of the user, a height calculation unit that calculates a height of a sensor by using sensor data including a spatial acceleration and a spatial angular velocity measured by sensors mounted on each of the both feet of the user, and a step width calculation unit that calculates a step width of the user by using the distance between the both feet measured at the same timing and the height of the sensor.

Abstract: The invention relates to a method for determining an advanced biomechanical gait parameter value from data generated by one or more motion sensors of a sole, said method including: a step (200) of acquiring data generated by one or more motion sensors of a sole; a step (300) of calculating an orientation value of the sole; a step (600) of identifying an activity associated with a motion unit; a step (700) of identifying at least two key moments of the motion unit for which an activity has been identified; and a step (800) of determining an advanced biomechanical gait parameter value, said determination including calculating a biomechanical gait parameter value for at least one of the identified key moments and from the acceleration, angular velocity, and/or orientation values of the sole.

Abstract: The present disclosure relates to a method for manufacturing an insertion guide needle for a continuous blood glucose monitoring device. The present disclosure provides a method for manufacturing an insertion guide needle for a continuous blood glucose monitoring device, by which: an insertion guide needle can be manufactured through a cutting process and a bending process of a needle raw plate, so that a complicated manufacturing process is unnecessary, and can thus be easily manufactured through a simple process; an enlargement incision part for continuous enlargement and incision, etc.

Abstract: A non-invasive measuring device is provided with: an irradiation unit which is for irradiating a specific position on a test subject with light; a light intensity detection unit which is disposed at a position on a blood vessel of the test subject for detecting a first light intensity of light; a light intensity detection unit which is disposed at a position not located on a blood vessel of the test subject for detecting a second light intensity of light; and a control unit which calculates a third light intensity of the blood in a blood vessel from the first light intensity and the second light intensity, a correct attenuation coefficient from a temporary attenuation coefficient obtained from the third light intensity by means of a calibration function, and an equivalent scattering coefficient and an absorption coefficient separately from the attenuation coefficient through measurement of multiple wavelengths.

Abstract: Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.

Abstract: Methods, systems, and devices for modeling a relationship between glucose sensitivity and a sensor electrical property are described herein. More particularly, the methods, systems, and devices describe partitioning an input signal feature space relating glucose sensitivity and a sensor electrical property into subspaces and training a model for each subspace. For example, the subspace models may form a mosaic of models, for which the output is more accurate than a single model.

Abstract: Digital and graphical user interfaces for third party analyte monitoring applications are provided. For example, disclosed herein are various embodiments of methods, systems, and interfaces for connection interfaces, alarm notification settings interfaces, and logbook interfaces in a third party analyte monitoring application. In addition, various embodiments of interface enhancements are described, including enhanced visibility mode and interfaces for setting up a third party analyte monitoring application, among other embodiments.

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Abstract: Embodiments described herein relate to an analyte monitoring device having a user interface with a display and a plurality of actuators. The display is configured to render a plurality of display screens, including a home screen and an alert screen. The home screen is divided into a plurality of simultaneously displayed panels, with a first panel displays a rate of change of continuously monitored analyte levels in interstitial fluid, a second panel simultaneously displays a current analyte level and an analyte trend indicator, and a third panel displays status information of a plurality of components of the device. When an alarm condition is detected, the display renders the alert screen in place of the home screen, the alert screen displaying information corresponding to the detected alarm condition. Furthermore, the actuators are configured to affect further output of the analyte monitoring device corresponding to the detected condition.

Abstract: A detecting device includes: a first light-emitting unit configured to emit first light having a green wavelength band; a second light-emitting unit configured to emit second light having a wavelength band higher than that of the green wavelength band; and a light-receiving unit configured to receive the first light emitted from the first light-emitting unit and emitted from a living body and the second light emitted from the second light-emitting unit and emitted from the living body. The light-receiving unit includes a first light-receiving region configured to receive the first light, a second light-receiving region provided at a position farther away from the first light-emitting unit than the first light-receiving region and configured to receive the second light, and a first filter provided in one of the first light-receiving region and the second light-receiving region and configured to selectively transmit light in a corresponding wavelength band.

Abstract: Embodiments of the invention provide amperometric analyte sensors having optimized elements such as interference rejection membranes, and associated architectures, as well as methods for making and using such sensors. While embodiments of the innovation can be used in a variety of contexts, typical embodiments of the invention include glucose sensors used in the management of diabetes.

Abstract: The affective state called flow is described as a state of optimal experience, total immersion, and high productivity. As an important metric for various scenarios ranging from (professional) sports to work environments and user experience evaluation, it is widely studied using traditional questionnaires. To make flow measurement accessible for online real-time environments, to automatically determine a user's flow state based on physiological signals measured with a wearable device, a system and method is presented to play the game Tetris® at different difficulty levels, resulting in boredom, stress, and flow. A CNN is used to achieve 70% accuracy in detecting flow-inducing values.

Abstract: Disclosed herein is a non-invasive urinary output measuring system having a urinary output measuring device and a fluid sensor system. The urinary output measuring device includes a receptacle body having a proximal opening, the receptacle body defining a collection cavity configured to receive a volume of fluid. The collection cavity includes a distal opening and an internal hydrophobic surface. The fluid sensor system is configured to measure the volume of fluid and includes a fluid sensor, a console including a processor further includes non-transitory computer-readable medium having a plurality of logic modules, one or more light indicator, and an opening mechanism configured to detachably seal the distal opening, the opening mechanism including a cover coupled to the receptacle body, and a lever configured to transition the opening mechanism between a closed configuration and an opened configuration.

Abstract: [Problem] Provided is an electronic functional member of superior wear resistance. [Solution] The present invention comprises a fiber network constituted by a water-soluble resin and a poorly water-soluble resin, and an electroconductive member formed on the fiber network. The water-soluble resin and poorly water-soluble resin are, for example, polyvinyl alcohol derivatives. In accordance with an embodiment of the electronic functional member according to the present invention, the fiber network is formed by layering a first fiber network constituted by fibers containing a water-soluble first resin and a second fiber network constituted by fibers containing a poorly water-soluble second resin. Alternatively, the fiber network may be constituted by fibers containing the water-soluble first resin and fibers containing the poorly water-soluble second resin. Alternatively, the fiber network may be constituted by fibers containing the water-soluble first resin and the poorly water-soluble second resin.