Abstract: An electrode arrangement measures electric voltages and currents in the human body and provides electro-simulation of the human body. The electrode arrangement contains an electrode array with a flexible support. A number of electrodes are arranged in a grid on the same side of the support and slots are disposed between the individual electrodes starting from the outer edge of the support. An elastic intermediate layer that has one recess for each electrode is provided, each recess defining a cavity to be filled with an electrically conductive gel.

Abstract: Systems, interfaces, and methods are described herein for evaluation and adjustment cardiac therapy. The systems, interfaces, and methods may utilize, or include, a graphical user interface to display various information with respect to a plurality of external electrodes and electrical activity monitored using such external electrodes and to allow a user to adjust what information to display.

Abstract: Apparatus and methods remove a voltage offset from an electrical signal, specifically a biomedical signal. A signal is received at a first operational amplifier and is amplified by a gain. An amplitude of the signal is monitored, by a first pair of diode stages coupled to an output of the first operational amplifier, for the voltage offset. The amplitude of the signal is then attenuated by the first pair of diode stages and a plurality of timing banks. The attenuating includes limiting charging, by the first pair of diode stages, of the plurality of timing banks and setting a time constant based on the charging. The attenuating removes the voltage offset persisting at a threshold for a duration of at least the time constant. Saturation of the signal is limited to a saturation recovery time while the saturated signal is gradually pulled into monitoring range over the saturation recovery time.

Abstract: A system is provided that includes one or more processors, and a memory coupled to the one or more processors. The memory stores program instructions, and the program instructions are executable by the one or more processors. When executed, the one or more processors obtain cardiac activity (CA) signals for a series of beats, and identify whether a characteristic of interest (COI) from a first segment of the CA signals exceeds a COI limit. The one or more processors also analyze morphology of the CA signals for the series of beats responsive to the first segment of the CA signals exceeding the COI limit, and based on the analyze operation, identify a premature ventricular contraction (PVC) within the series of beats.

Abstract: The present disclosure encompasses an “artifact score” derived from the signal characteristics of an acquired 12-lead ECG, (2) a “patient context score” derived from key elements of the patient's history, presentation, and pre-hospital emergency care, and (3) techniques for integrating these scores into an emergency medical care system.

Abstract: Embodiments of a wearable monitoring device system can include a wearable monitoring device comprising one or more patient physiological sensors and a detector to zonelessly detect arrhythmias from physiological signals sensed by the one or more sensors, and optionally other signals. In embodiments the detector includes a processor configured with a sudden rate change onset (SRCO) algorithm, one or more arrythmia detection algorithms and, optionally, a noise detection algorithm. In embodiments, in response to detecting SRCO, the wearable monitoring device or a remote system that receives data from the wearable medical device determines whether the patient has an arrhythmia from physiological signals sensed by the one or more sensors.

Abstract: Systems and methods to access the functionally distributed network of the brain to allow for directly accessing, monitoring, and/or communicating with specific regions of the brain when interacting with an external device.

Abstract: An exemplary system, method and computer-accessible medium for providing an indication(s) to administer an anesthesia medication(s) to a patient(s) can include, for example, receiving electroencephalogram (“EEG”) information for the patient(s), determining a power spectra(s) of an alpha band of the patient(s) from the EEG information, and providing the indication(s) to administer the anesthesia medication(s) to the patient(s) based on a predetermined drop in the power spectra(s). The predetermined drop can be about 20%. An amount to assign for the predetermined drop can be received. A first derivative power spectra can be determined based on the alpha band, and the indication(s) to administer the anesthesia medication(s) to the patient(s) can be provided based on a further predetermined drop in the first derivative power spectra.

Abstract: A system and method for screening a subject for a pupillary response to an olfactory stimulus as an indication for COVID-19. The method can include providing the olfactory stimulus to the subject via a scent dispenser, measuring a pupillary response of the subject to the olfactory stimulus via a detector, and comparing the measured pupillary response to a reference. The reference could include a default value or a characterized pupillary response for the subject or a population of individuals to the olfactory stimulus. The method can further include determining whether the subject demonstrates a diminished or an absent response to the olfactory stimulus according to whether the measured pupillary response differs from the reference by a threshold and providing an alert accordingly. The alert can include an intervention associated with COVID-19, such a recommendation to seek medical evaluation or take a COVID-19 diagnostic test.

Abstract: A system and method for screening a subject for a pupillary response to an olfactory stimulus as an indication for COVID-19. The method can include providing the olfactory stimulus to the subject via a scent dispenser, measuring a pupillary response of the subject to the olfactory stimulus via a detector, and comparing the measured pupillary response to a reference. The reference could include a default value or a characterized pupillary response for the subject or a population of individuals to the olfactory stimulus. The method can further include determining whether the subject demonstrates a diminished or an absent response to the olfactory stimulus according to whether the measured pupillary response differs from the reference by a threshold and providing an alert accordingly. The alert can include an intervention associated with COVID-19, such a recommendation to seek medical evaluation or take a COVID-19 diagnostic test.

Abstract: Provided are systems, methods, and kits for multifunctional smell assessment. The kits may comprise a first surface adhered by a first releasable adhesive comprising an odorous volatile compound; and the system for registering if the odorous volatile compound is detected by a user. The system or method may comprise queries for obtaining a first input on whether the user detects and identifies the odorous volatile compound, and an intensity by which the odor is perceived.

Abstract: A system and method for testing an effect of light exposure on a skin sample include a solar simulator arranged to administer a combination of visible light (VL) and long wavelength ultraviolet radiation (UVA1) to the skin sample. The solar simulator includes a lamp for generating a light beam and at least one customized filter for receiving the light beam and emitting a VL+UVA1 spectral output having a wavelength range of 370-700 nm for irradiating the skin sample.

Abstract: The objective of the present invention is to provide a hardness meter which estimates hardness in a stable manner regardless of a compression strength. A hardness meter includes: a movable portion which is continuously pressed against an object to be measured; a sensor which outputs an output signal reflecting a reaction force at a part of the object to be measured; a motive force mechanism that causes the movable portion to perform a piston motion; a hardness estimating portion which estimates the hardness of the object on the basis of an alternating current component of the output signal, generated by the piston motion; a position estimating portion which estimates a measurement position information by shooting with a camera; and a hardness map display portion which maps and displays the hardness on a schematic diagram of the surface of a living body based on the measurement position information.

Abstract: The present disclosure provides methods for evaluating tissue damage and the use of spatial variation in Sub-Epidermal Moisture (SEM) values to determine damaged tissue for clinical intervention. The present disclosure provides methods of identifying deep and early-stage pressure-induced injuries or ulcers (PI/PU). The present disclosure provides algorithm for computing SEM delta values which inform clinical decision-making for developing intact skin PI/PUs including suspected deep tissue injury (sDTI) and Stage I PI/PUs.

Abstract: A pressure monitoring system and method for warning a patient or caregiver that soft tissue pressure has exceeded some predetermined level that over time would necessitate moving the patient to prevent or at least reduce a risk of soft tissue damage. The pressure monitoring system and method utilize a dressing assembly adapted to be applied to or near a surface of the patient's body and generate electrical outputs corresponding to soft tissue pressure sensed at the surface. The dressing assembly includes a pocket formed therein for removable, secured and protected insertion of one or more sensors.

Abstract: A body worn or implantable hearing prosthesis, including a device configured to capture an audio environment of a recipient and evoke a hearing percept based at least in part on the captured audio environment, wherein the hearing prosthesis is configured to identify, based on the captured audio environment, one or more biomarkers present in the audio environment indicative of the recipient's ability to hear.

Abstract: Various types of data can be collected regarding the physical or mental health of a user, as may relate to sleep of the user over a period of time. Health metrics can be determined from this data that can enable the user to be associated with a particular health type or category. For sleep, this can include associating the user with a sleep animal that has specific characteristics. This can help a user to better understand that user's sleep, and how that sleep compares to sleep of others. In addition to being able to provide health information in a way that is easy to understand, such an approach can also help to make more accurate recommendations or take specific actions to help improve the health of a user, such as to improve sleep. This can include making recommendations to a user or automatically adjusting operation of at least one device.

Abstract: A method of evaluating rehabilitation potential in patients experiencing painful musculoskeletal or neuropathic conditions or both, by maximizing multidimensional rehabilitation outcomes by better identifying the specific needs of each patient; understanding the many obstacles to rehabilitation success falling into motivational, physical, and emotional categories; physical obstacles to rehabilitation including but not limited to incorrect diagnoses and deconditioning; emotional obstacles including fear avoidance, catastrophizing, generalized anxiety, depression, childhood adverse events, emotional awareness deficits; and motivational obstacles including factitious disorder, personality disorders, malingering and apathy. The resulting comprehensive pain rehabilitation program combines multiple treatment options. Medicinal treatments include anti-inflammatory medications; muscle relaxants; opioids and cannabinoids; injection therapies; neuropathic medications; and pain adjuvant medications.

Abstract: A method and system for rapidly predicting cardiac response to a heart condition and treatment strategy of a patient. Predictions are accomplished using a compartmental model that includes systemic and pulmonary circulations represented as a system of resistors and capacitors together with chambers of the heart represented as simple geometric shapes such as spheres or assemblies of spheres or other analytic equations that relate pressure and volume to stress and strain. The model is calibrated using disease-specific data sets for a specific heart condition. Simple geometry modeling allows for rapid use such that hemodynamic parameters may be tuned for optimal accuracy. Treatment strategies may be modified and re-simulated in real time if necessary to achieve a more optimal outcome and treatment.

Abstract: Embodiments may provide techniques that may provide the capability to provide self-guided, self-directed diagnostics and treatment of neural conditions. For example, in an embodiment, a system may comprise program instructions and data stored in the memory to configure the processor to control the stimulation devices to generate and transmit stimulation signals, a plurality of sensing devices connected to signal input circuitry interfacing the processor with the sensing devices, program instructions and data stored in the memory to configure the processor to receive sensed signals from the sensing devices, and program instructions and data stored in the memory to configure the processor to perform dynamic closed loop feedback of the stimulation signals based on the received sensed signals to provide self-guided, self-directed diagnostics and treatment of neural conditions using at least one recipe for a treatment strategy guided by artificial intelligence.

Abstract: Disclosed herein are systems and methods for the delivery of insulin and pramlintide using an automated insulin delivery system. In a first embodiment, a drug delivery system is configured to deliver independent doses of insulin and pramlintide. The system monitors the user's blood glucose level and determines when a meal is been ingested and, in response, delivers the dose of pramlintide which, in turn alters the required delivery of insulin. In the second embodiment, the drug delivery system is configured to deliver a co-formulation of insulin and pramlintide as basal doses. The total amount of pramlintide delivered in a most recent pre-determine period of time, for example, 24 hours, is used to alter the aggressiveness of the algorithm which determines the basal doses of the co-formulation.

Abstract: Systems and methods are provided for managing hyperglycemia and hypoglycemia by reconciling incoming data to provide safe and reliable control to range using automatic bolus determination wherein the rate of insulin delivery is dependent on the level of hyperglycemic risk or hypoglycemic risk. Additionally, some implementations are directed to converting insulin delivery into a rate based on glycemic risk.

Abstract: A wearable device for measuring intoxication of a user can include a band with a sample intake port, one or more processors or other circuitry that analyze a sample from the user, the sample being inducted into the sample intake port, and determine a level of intoxication of the user based on an analysis of the sample, and an indicator that visually displays the level of intoxication of the user on an exterior surface of the band.

Abstract: In one embodiment, a hydration sensor or sensing element is configured to measure the hydration level of a user. The sensing element can include a water-permeable material positioned in between two water-impermeable material. The sensing element can be coupled to a bottle of fluid, or a carrier with a timer. The sensing element can be incorporated into a handheld device. The sensing element can be a disposable element, an element applicable for more than one-time use, or a re-usable element. The sensing element or sensor can be calibrated for a specific user or a group of users. One or more additional sensors that do not measure hydration level of the user can be coupled to a hydration sensing element to determine the amount of fluid consumption for the user in different conditions.

Abstract: Example systems, methods, and apparatus, including cognitive platforms, are provided for computing performance metrics of an individual based at least in part on user interaction(s) with computerized tasks and/or interference and at least one physiological measure of the individual, where the performance metric provides an indication of the cognitive abilities of the individual. The apparatus can be coupled to at least one physiological component to perform the physiological measurement of the individual. The apparatus also can be configured to adapt the tasks and/or interferences to enhance the individual's cognitive abilities.

Abstract: The present invention relates to a method and a device for detecting a nerve, the method comprising the steps of: acquiring a learning image including a plurality of splices arranged in a coronal plane direction; generating learning data in which a nerve and mental tubercle and/or a mandibular angle, serving as a reference for detecting the nerve, are set in the learning image, and learning the learning data so as to generate a learning model; inputting a target image into the learning model; and detecting a nerve from the target image on the basis of the learning data, and application through other embodiments is possible.

Abstract: A temperature-sensing face covering, such as a facemask or a face shield, with a temperature sensor and display unit therein to provide for hands free temperature readings that go wherever the individual goes and continue to measure the individual's temperature throughout the day. The temperature-sensing face covering is simple and does not require the sites of work or other places to have any additional equipment, and provides continual readings that could very easily change throughout the day and be missed because at the beginning of the day the individual did not have a fever.

Abstract: Systems and methods are provided herein to detect a presence of a target substance and disseminate a notice of the target substance.

Abstract: The wearable device (10) comprises a liveness detection module (103) arranged to detect whether the wearable device (10) is being worn by a user. The wearable device (10) comprises a communicator (107) arranged to transmit a message to a server in response to the liveness detection module (103) detecting that the wearable device (10) is being worn. Prior to the liveness detection module (103) detecting that the wearable device (10) is being worn by a user, the wearable device (10) is arranged to operate in a low power mode.

Abstract: A medical system for monitoring a left atrial pressure in a heart of a patient may include an implantable device including an expandable framework and a first sensor secured to the expandable framework and an external component configured to communicate wirelessly with the implantable device. The first sensor may be configured to detect a first measurement. The first sensor may be a pressure sensor and the first measurement may be the left atrial pressure. The implantable device or the external component may include a processor configured to create a first trend for the first measurement. The processor may be configured to use the first trend to modify the first measurement prior to outputting a corrected result.

Abstract: A dental sensor system (100), including a first tooth attachment device (101-1) for attachment to a first tooth (103-1); a second tooth attachment device (101-2) for attachment to a second tooth (103-2); a sensor rail (105) between the first and second tooth attachment devices (101-1; 101-2); and a dental sensor (107) positionable along the sensor rail (105).

Abstract: For improving the safety of optical measurements performed with an apparatus comprising a set of light sources and detectors controlled by an electronic unit for measuring an optical or physiological parameter in a scattering medium, in particular human tissue, based on a set of measurement wavelengths, it is suggested that the apparatus features at least one optical contact detector, for example in the form of a photodiode or a light sensitive end facet of an optical fiber or the like, for measuring a detection light quantity resulting from a detection wavelength, and wherein the apparatus issues an alarm signal, in case the measured detection light quantity indicates a low optical coupling efficiency between the apparatus and the medium.

Abstract: A wearable electronic device includes a body, a housing component, a band operable to attach the body to a body part of a user, and a force sensor coupled to the housing component. The force sensor is operable to produce a force signal based on a force exerted between the body part of the user and the housing component. A processing unit of the wearable electronic device receives the force signal from the force sensor and determines the force exerted on the housing component based thereon. The processing unit may use that force to determine a tightness of the band, determine health information for the user, adjust determined force exerted on a cover glass, and/or to perform various other actions.

Abstract: Described herein are catheters for use with Optical Coherence Tomography (OCT) that include an optical fiber core having a first refractive index and an interface medium having a second refractive index, where the first and second refractive indexes are mismatched such that receiving electronics configured to receive optical radiation reflected from the reference interface and the target operate in a total noise range that is within 5 dB of the shot noise limit. These OCT catheters may include a silicon die mirror having a reflective coating that is embedded in the interface medium. The optical fiber can be fixed at just the distal end of the catheter, and may be managed within a handle that is attached to the proximal end of the catheter body, and is configured to allow rotation of the both catheter body and the optical fiber relative to the handle.

Abstract: Examples of systems and methods for classifying SpO2 levels using smartphones are described. A wideband light source (e.g., a flash) may be used to illuminate a finger. A wideband imaging sensor (e.g., a camera) may be used to capture images of the illuminated finger. The smartphone may apply per-color channel gain adjustments to the captured images. The adjusted pixel data may be used as the basis of input to a classifier (e.g., a deep learning model). The classifier may be trained on ground truth data, such as from an induced hypoxia study. The classifier may output an SpO2 level blood in the finger.

Abstract: A biosignal sensor includes a light-emitting element, a photo-detective element configured to detect a biosignal from light reflected from an in-vivo target, a first polarizer configured to selectively transmit light in a first polarization direction, and a second polarizer configured to selectively transmit light in a second polarization direction. The light-emitting element includes a first light-emitting element overlapped with the first polarizer in a vertical direction, the photo-detective element includes a first photo-detective element overlapped with the second polarizer in the vertical direction, the first light-emitting element and the first photo-detective element are parallel to each other along a first direction that is perpendicular to the vertical direction, and the first polarization direction and the second polarization direction are perpendicular to each other.

Abstract: An apparatus for estimating biological information of a user may include a light source configured to emit light to an object of the user; an image sensor comprising a pixel array, and configured to acquire successive image frames by detecting light scattered or reflected from the object of the user; and a processor configured to: select a predetermined number of pixel-rows from among pixel-rows of the image sensor, detect signal intensities in the predetermined number of pixel-rows for each image frame of the successive image frames, correct the signal intensities, combine the signal intensities for each image frame of the successive image frames based on correcting the signal intensities, acquire a photoplethysmogram (PPG) signal based on combining the signal intensities, and estimate the biological information of the user based on the PPG signal.

Abstract: According to various embodiments, a machine-learning based system for diabetes analysis is disclosed. The system includes one or more processors configured to interact with a plurality of wearable medical sensors (WMSs). The processors are configured to receive physiological data from the WMSs and demographic data from a user interface. The processors are further configured to train at least one neural network based on a grow-and-prune paradigm to generate at least one diabetes inference model. The neural network grows at least one of connections and neurons based on gradient information and prunes away at least one of connections and neurons based on magnitude information. The processors are also configured to output a diabetes-based decision by inputting the received physiological data and demographic data into the generated diabetes inference model.

Abstract: The video based detection of pulse waveform includes systems, devices, methods, and computer-readable instructions for capturing a video stream including a sequence of frames, processing each frame of the video stream to spatially locate a region of interest, cropping each frame of the video stream to encapsulate the region of interest, processing the sequence of frames, by a 3-dimensional convolutional neural network, to determine the spatial and temporal dimensions of each frame of the sequence of frames and to produce a pulse waveform point for each frame of the sequence of frames, and generating a time series of pulse waveform points to generate the pulse waveform of the subject for the sequence of frames.

Abstract: A method (100) of determining the temporal occurrences of one or more events characterising movement of a person is provided. The method comprises processing (102) kinematic data relating to movement of the person to determine the temporal occurrences of the events. The processing of the kinematic data comprises processing the kinematic data using the Teager-Kaiser energy operator. A system for measuring the temporal occurrences of one or more events characterising movement of a person is also provided.

Abstract: Disclosed are techniques including accessing historical physiological data of a person; presenting a graph view of a historical time period, where the graph view includes at least a portion of the historical physiological data plotted over the historical time period and includes one or more historical events which occurred during the historical time period; receiving user input indicative of a marker for an event, of the one or more historical events, being adjusted from a first position in the historical time period to a second position in the historical time period; responsive to receiving the user input, accessing adjusted physiological data for the person from at least the time point in the historical time period to an end of the historical time period, where the adjusted physiological data has been determined based on the adjusted marker for the event marker and a physiological model for the person; and presenting the adjusted physiological data.

Abstract: Disclosed are treatment information display device and method for displaying treatment history on an image of teeth in an accumulated manner. The treatment information display method enables a user to recognize at once a past treatment history, a current treatment status, and a future treatment plan by displaying, on the image of teeth, treatment information for the past, present, and future. In addition, the treatment information display method can provide the user with pieces of treatment information displayed on different images of teeth, by displaying, in an accumulated manner, the pieces of treatment information displayed on a plurality of teeth images.

Abstract: A computing system for measuring and monitoring patient biomarkers for detecting or predicting a post-surgical hysterectomy complication may be provided. A post-surgical hysterectomy complication may be predicted or detected by comparing measured/processed patient biomarker data with a corresponding determined threshold value. The comparison of the measured/processed patient biomarker data and the corresponding threshold may be performed in association with a context. The context may be based on at least one of a hysterectomy surgery recovery timeline, at least one situational attribute, or at least one environmental attribute. A notification message associated with a predicted or detected post-surgical hysterectomy complication may be sent (e.g., sent in real time) to a patient device or a healthcare provider's device. The notification message may be supplemented by a severity level message.

Abstract: A method, system, and/or apparatus for automatically monitoring for possible mental or physical health concerns. The method or implementing software application uses or relies upon location information available on the mobile device from any source, such as cell phone usage and/or other device applications. The method and system automatically learns user activity patterns and detects significant deviations therefrom. The deviations are automatically analyzed for known correlations to mental or physical concerns, which can then be automatically communicated to a relevant friend, family member, and/or medical professional.

Abstract: The present invention relates to a method for assisting an interviewing party in deciding a response action in response to an interview between said interviewing party and an interviewee party. The method comprises providing a processing unit and inputting the voice of the interviewee party into the processing unit as an electronic signal, and processing the electronic signal by means of said processing unit in parallel with the interview taking place. The method further includes an anomaly routine comprising a statistically learned model, and by means of said statistically learned model determining a respective number of samples of said sequence of samples being an anomaly of said statistically learned model and returning to said anomaly routine for processing a subsequent number of samples of said sequence of samples by said anomaly routine.

Abstract: The health detection and alert system comprises a user's computing device comprises a camera, an accelerometer sensor, a gyro sensor, a temperature sensor, a heart rate sensor and a GPS sensor; a user to detect real time health condition of a user, wherein the user interface is configured to: detect accident and dizzy falling upon comparing a threshold acceleration value and current acceleration value detected using the accelerometer sensor; detect vehicle accident upon processing captured image/video using a vehicle camera; detect real time critical health condition upon comparing threshold temperature and heart rate of the user with real time body temperature and heart rate of the user; and a processor to send an alert to a registered number along with rescue team if a user met with an accident or the health of the user is in critical condition using a communication module.

Abstract: Radiology holding device (1) for a radiology apparatus (50) such as an X-ray apparatus (51), MRT apparatus (52), CT apparatus (53) or radiotherapy apparatus (54), comprising an attachment device (2) and pivotally accommodated thereat, a supporting arm (3) with at least one axle component (4) and a supporting component (5). Furthermore, a locking device (6) is provided for locking the supporting arm (3) in at least one locking position (7). An actuating mechanism (8) serves to actuate the locking device. A holding device (9) provided for attachment to the supporting arm (3) is comprised to provide a patient with a holding means. The axle component (4) of the supporting arm (3) is pivotally accommodated on the attachment device (2). The actuating mechanism (8) comprises a transfer component (11) passing through a hollow section (10) of the axle component (4).

Abstract: The radiographic system includes an exposure table on which a breast of a subject is placed, a compression plate that compresses the breast placed on the exposure table, a marker having a two-dimensional pattern provided on the compression plate, a radiation source that irradiates the compressed breast with radiation, a camera that captures a visible light image including the marker, and a processor that derives height information of the compression plate with respect to the exposure table based on a marker image showing the marker reflected in the visible light image.

Abstract: A computed tomography (CT) scanning apparatus that includes a set of X-ray sources and a set of flat panel detectors with a set of source collimators and a set of detector collimators therebetween. The design of the openings of the set of detector collimators is such that the images received by the set of flat panel detectors may be combined, or stitched together to generate a single X-ray image.

Abstract: An X-ray system is described with a scatter radiation shielding device to be mounted underneath an operating table. The shielding device (10) comprises one or more layers of a radiation blocking material (6) and a cut-out (8) in the one or more layers. The cut-out extends from a point in or near a center of the one or more layers towards an edge to allow radiation transmission to pass. The shielding device is rotatable around a rotation axis. The shielding device substantially reduces the scatter radiation originating from the patient.