Abstract: An optical system and an imaging method are disclosed, wherein the optical system comprises a multifilament conductor and an optical diffuser for imaging an intensity pattern onto the multifilament conductor, the intensity pattern representing phase information of light emitted from one or more three-dimensional objects; wherein the multifilament conductor is configured to transmit the intensity pattern in the form of a plurality of pixels to an evaluation system, and wherein the evaluation system is configured to generate an image based on the intensity pattern transmitted by the multifilament conductor, the image representing the one or more three-dimensional objects.

Abstract: Techniques for operating and monitoring an endoscopic balloon dilation system.

Abstract: An optical system includes a plurality of lenses. The plurality of lenses have refractive index distributions in which a refractive index changes in directions orthogonal to optical axes. The optical axes of the plurality of lenses are disposed on the same straight line as each other. The plurality of lenses are manufactured on the basis of same design values relating to an on-axis refractive index and a refractive index distribution constant. When rotation positions around the optical axes of the plurality of lenses at which a total aberration amount of the plurality of lenses reaches a maximum are set as reference rotation positions for the plurality of lenses, any one of the plurality of lenses is arranged at a position acquired by relatively rotating the reference rotation position around the optical axis.

Abstract: The disclosure extends to systems and methods for reducing the area of an image sensor by employing bi-directional pads used for both image data issuance and configuration command reception and internal supply voltage generation, for reducing the number of conductors in an endoscope system.

Abstract: To provide an endoscope cap includes: a cover having a cylindrical shape with a bottom; a pedestal; and an elevator rotatably supported by the pedestal. The pedestal includes: a base; a support wall, rising from an edge of the base, and extending in an axial direction of the cover to support the elevator; a distal tip wall extending from a distal tip of the support wall in the same direction as the base; a bottom fixing protrusion protruding from the distal tip wall in a direction opposite to the support wall; and a lateral face fixing protrusion protruding from the base in a direction opposite to the support wall. The cover includes: a first fixing hole into which the bottom fixing protrusion is inserted, being disposed in the bottom; and a second fixing hole into which the lateral face fixing protrusion is inserted, being disposed in a lateral face.

Abstract: A magnetic control device (30) for a capsule endoscope (10) including at least a first magnet (11) and an imaging device (12), and the capsule endoscope (10) is located in a tissue cavity (3). The magnetic control device (30) includes a second magnet (31) and a first induction coil (32) arranged around the second magnet (31). The magnetic control device (30) is configured to generate a driving force to the capsule endoscope (10) to move the capsule endoscope (10) from a first position (P1) in the tissue cavity (3) to a second position towards an opposite side in the tissue cavity (3); to control a variable magnetic field to decelerate the capsule endoscope (10) to a predetermined speed when the capsule endoscope (10) approaches the second position (P2); and to generate the variable magnetic field for the capsule endoscope (10).

Abstract: An endoscopic imaging device is disclosed. The device includes a body portion configured to be held in a user's hand and an endoscope portion configured to direct light onto a target. At least one excitation light source is configured to excite autofluorescence emissions of tissue cells and fluorescence emissions of induced porphyrins in tissue cells of the target. A white light source is configured to illuminate the surgical margin during white light imaging of the target. The device also includes an imaging sensor and a first optical filter configured to filter optical signals emitted by the target responsive to illumination with excitation light and permit passage of autofluorescence emissions of tissue cells and fluorescence emissions of the induced porphyrins in tissue cells to the imaging sensor.

Abstract: A process to clean medical devices, such as endoscopes, with a turbulent cleaning solution is described. The process includes providing cleaning solution in a first delivery system and providing a gas in a second delivery system, wherein the first and second delivery system are connected to a third delivery system that allows the cleaning solution and gas to combine to provide a turbulent cleaning solution that can be passed through a lumen of a medical device. The process is generally accomplished by use of a peristaltic pump with two heads; one head for each of the delivery system. The resultant turbulent cleaning solution provides enough force to dislodge most body fluids, debris, bacteria and/or virus(es) from the surface of the medical device without the requirement for physical scrubbing or brushing of the surface.

Abstract: A scope (1) for examining or surgically treating ears comprising a probe (2); at least one visualiser (3) on the probe having an optical configuration (7), and a light source (42) wherein the visualiser (3) is articulatable about a visualiser articulation axis (3a) by an orienting mechanism (4) for optimal viewing of the ear.

Abstract: Provided are an ophthalmologic device and a method of controlling the same capable of accurately and reliably acquiring ocular characteristics of a subject eye. The ophthalmologic device includes: a face supporting unit configured to support a face of an examinee; an anterior ocular segment image acquiring unit configured to repeatedly acquire an anterior ocular segment image of the subject eye of the face supported by the face supporting unit; a pupil image detecting unit configured to detect a pupil image of the subject eye for each anterior ocular segment image based on the anterior ocular segment image repeatedly acquired by the anterior ocular segment image acquiring unit; and a determining unit configured to determine whether or not the face is properly supported by the face supporting unit based on a result of detection of the pupil image for each anterior ocular segment image by the pupil image detecting unit.

Abstract: A visual field assessment system (100) comprises a display device (116) having a display area; a user input device (118), and a processor (102, 104). The processor is configured to intermittently display a first visual stimulus (306) in a central display region (301 A) of the display area and intermittently display a second visual stimulus (308) in a peripheral display region (301 B) of the display area. The processor determines whether the user has correctly visually detected the second visual stimulus based on use of the user input device, and selectively displays a graphical object (310) moving from the peripheral display region towards the central display region based on the determination.

Abstract: The present disclosure relates to a method for assessing color vision. The method includes identifying one or more steady-state visual evoked potentials (SSVEPs) to identify metamers. The present disclosure further relates to devices for assessing color vision that use metamers identified via steady-state visual evoked potentials (SSVEPs). Also disclosed herein are methods of treating color vision deficiency, systems for identifying a response to one or more metameric stimuli, methods of individually modifying color vision, methods for assessing color vision using neural activity as a means to personalize visual displays, and methods for assessing light sensitive cells in the nervous system using flashing lights.

Abstract: An ophthalmologic apparatus includes: an objective lens 18 configured to face a subject's eye E; an illumination optical system 1c configured to irradiate the subject's eye E with illumination light L1; a measurement optical system 1 b configured to take an interference image of corneal reflection light R1, which is a reflection of the illumination light L1, through the objective lens 18; an observation optical system 1a configured to image an anterior segment of the subject's eye E through the objective lens 18; a control unit 2 configured to process information on imaging by the measurement optical system 1b and the observation optical system 1 a; and the control unit 2 configured to simultaneously output, to a single output unit 3, tear film information calculated from the interference image by the measurement optical system 1 b, and information on the anterior segment E imaged by the observation optical system 1a.

Abstract: An ophthalmic system for generating a topography of an anterior corneal surface of an eye comprises an illuminator, cameras, and a computer. The illuminator illuminates the anterior corneal surface of the eye with a Placido pattern, which reflects the Placido pattern. Each camera generates an image of the reflected Placido pattern to yield multiple images. At least one camera is oriented off an axis of the eye. For each image, the computer calculates a curvature value for each data point of the image, where a data point corresponds to a surface point of the anterior corneal surface. The calculations yield curvature values for each surface point. The computer determines the curvature at each surface point from one or more curvature values for the surface point. The computer generates the topography of the anterior corneal surface from the curvatures at the surface points of the anterior corneal surface.

Abstract: An ophthalmic illumination and imaging system with transscleral/transpalpebral illumination of the eye fundus comprises a light-delivering device with a plurality of emitting areas; each of the emitting areas being configured to be independently controllable and directed towards the sclera of the intended eye to measure, providing transscleral oblique illumination of the eye fundus; an active eye aberration correcting system; and an imaging system configured to create multiple images of the eye fundus on multiple imaging sensors.

Abstract: A slit lamp microscope of an aspect example includes a scanner, a controller, and an image set creation processor. The scanner is configured to scan an anterior segment of a subject's eye with slit light to collect an image group. The controller is configured to control the scanner to apply two or more scans to the anterior segment. The image set creation processor is configured to create an image set by selecting a series of images corresponding to a scan area from two or more image groups collected by the scanner in the two or more scans.

Abstract: A vision screening device includes an image capture component. The vision screening device displays a chromatic aberration, captures an optical image using the image capture component, and estimates a refractive error based on the optical image.

Abstract: Systems and methods are disclosed to inspect an eye includes capturing an eye image using a mobile device camera; extracting features of the eye; applying a deep learning neural network to detect the eye for identification.

Abstract: Disclosed are various examples and embodiments of systems, devices, components and methods configured to classify, and to detect at least one location or type of at least one source of, at least one cardiac rhythm disorder in a patient's heart using one or more body surface electrodes, and/or intracardiac electrodes. Body surface electrogram data, and optionally intracardiac electrode data, representative of cardiac signals acquired from the patient are provided to a computing device, which in turn determines the location and type of the at least one source of the at least one cardiac rhythm disorder in the patient's heart using electrographic flow (EGF) methods, and then classifies same using electrographic volatility index (EVI) methods.

Abstract: A method for remote medical evaluation of a patient includes providing a patient-side application to a patient platform and a practitioner-side application to a practitioner platform, establishing an electronic communication connection between the patient platform and the practitioner platform, transmitting electronic command signals from the practitioner platform to the patient platform to remotely control one or more components of the patient platform, receiving at the practitioner platform information obtained from operation of the one or more remotely controlled patient platform components, and providing on the practitioner platform the obtained information to a medical practitioner. A non-transitory computer readable medium and a system to implement the method are also disclosed.

Abstract: A system for interfacing an in-body medical device with an external network includes a subdermal wideband on-body network (WON) hub, which in turn includes a hub rechargeable battery, a hub processor coupled to the hub rechargeable battery, a device interface configured to communicate with the in-body medical device, and coupled to the hub processor, and a hub-satellite near field communications wireless interface coupled to the hub processor. The system also includes a wearable WON server that in turn includes a server processor, a server-satellite interface coupled to the server processor, and an external network interface coupled to the server processor.

Abstract: System and method for processing, non-concurrently collected, electroencephalogram (EEG) data and resting state functional magnetic resonance imaging (rsfMRI) data, non-invasively, to create a patient-specific three-dimensional (3D) mapping of the patient's functional brain network. The mapping can be used to more precisely identify candidates of resective neurosurgery and to help create a targeted surgical plan for those patients. The methodology automatically maps the patient's unique brain network using non-concurrent EEG and resting state functional MRI (rsfMRI). Generally, the current invention merges EEG data and rsfMRI data to map the patient's epilepsy/seizure network. Correlated sections of the brain and inversely correlated sections of the brain are identified to determine which sections of the brain work in conjunction with each other and which sections work oppositely to each other during epileptic episodes.

Abstract: A three-dimensional (3D) optical coherence tomography angiography (OCTA) method and system based on feature space is provided. OCT signals of scattering samples in a 3D space are acquired by a collector; a theoretical classifier, local signal-noise ratios (SNRs) and decorrelation coefficients of the OCT scattering signals are combined to establish a two-dimensional (2D) feature space to realize classification of dynamic blood flow signals and static tissues. Specifically, computational analysis of first-order and zero-order autocovariance is used to obtain two features of SNR and decorrelation of each OCT scattering signal; a 2D inverse SNR (iSNR)-decorrelation feature (ID) space is established; and based on the multivariate time series theory, a linear classifier is established in the ID space to remove a static surrounding tissue background. The 3D OCTA method and system can improve the contrast of blood flow images and-improve the accuracy of blood flow quantification.

Abstract: The invention provides a body-worn monitor featuring a processing system that receives a digital data stream from an ECG system. A cable houses the ECG system at one terminal end, and plugs into the processing system, which is worn on the patient's wrist like a conventional wristwatch. The ECG system features: i) a connecting portion connected to multiple electrodes worn by the patient; ii) a differential amplifier that receives electrical signals from each electrode and process them to generate an analog ECG waveform; iii) an analog-to-digital converter that converts the analog ECG waveform into a digital ECG waveform; and iv) a transceiver that transmits a digital data stream representing the digital ECG waveform (or information calculated from the waveform) through the cable and to the processing system. Different ECG systems, typically featuring three, five, or twelve electrodes, can be interchanged with one another.

Abstract: A cardiac diastolic function assessment method, for use in the field of cardiac monitoring. The method comprises: noninvasively acquiring vibration information of the thoracic body surface of a subject; preprocessing the vibration information to generate hemodynamics-related information; determining a first parameter and a second parameter on the basis of the hemodynamics-related information; generating an indicating parameter on the basis of the first parameter and of the second parameter, and assessing the cardiac diastolic function of the subject on the basis of the indicating parameter.

Abstract: Disclosed is a cardiac diastolic function assessment method applicable to the field of cardiac monitoring. The method comprises: acquiring vibration information of the thoracic cavity body surface of an object in a noninvasive manner; preprocessing the vibration information to generate hemodynamic-related information; determining a target wave group on the basis of the hemodynamic-related information; determining the highest peak on the target wave group, determining a rising edge amplitude before the highest peak as a first characteristic value, and determining, as a second characteristic value, an amplitude between the highest peak and the subsequent lowest valley; and generating an indicating parameter on the basis of the first characteristic value and the second characteristic value, and assessing a cardiac diastolic function of the object on the basis of the indicating parameter.

Abstract: Provided is a technique capable of prompting execution of highly useful blood pressure measurement. That is, the blood pressure measuring apparatus according to an aspect of the present invention is a blood pressure measuring apparatus for performing blood pressure measurement, the blood pressure measuring apparatus including a notification unit that performs a notification to prompt a user to perform the blood pressure measurement, a time setting unit capable of setting a blood pressure measurement time by an instruction from the user, a storage unit that stores a recommended time period of the blood pressure measurement, and a control unit that performs control to cause the notification unit to start the notification based the blood pressure measurement time set by the time setting unit, and cause the notification unit to stop the notification when the recommend time period passes.

Abstract: A medical system including processing circuitry configured to receive a cardiac signal indicative of a cardiac characteristic of a patient from sensing circuitry and configured to receive a glucose signal indicative of a glucose level of the patient. The processing circuitry is configured to formulate a training data set including one or more training input vectors using the cardiac signal and one or more training output vectors using the glucose signal. The processing circuitry is configured to train a machine learning algorithm using the formulated training data set. The processing circuitry is configured to receive a current cardiac signal from the patient and determine a representative glucose level using the current cardiac signal and the trained machine learning algorithm.

Abstract: An early warning scoring system and method comprises a computing device, a plurality of sensors for acquiring physiological signals from a patient, wherein the sensors are functionally connected to the computing device, and at least one alarm adapted to output an alert upon an early warning score (EWS) exceeding a predetermined level. The computing device receives the physiological signals from the sensors, analyzes the physiological signals, and based on the analyzed signals, calculates the early warning score, and compares to the early warning score to predetermined limits and, if the score is outside the limits, triggers an alarm or actuates or modifies a treatment or medical intervention.

Abstract: Approaches described herein can determine one or more breathing phase patterns over a period of time using audio data captured by at least one microphone. The audio data can include one or more snores. A breathing phase pattern included within the period of time can be determined based at least in part on sensor data captured by one or more sensors in the electronic device. A determination can be made that a first breathing phase pattern represented by the audio data and a second breathing phase pattern represented by the sensor data are correlated. A determination can be made that the first breathing phase pattern represented by the audio data and the second breathing phase pattern represented by the sensor data both correspond to a user wearing the electronic device.

Abstract: A wearable device includes a substrate, at least one light emitting component mounted on one side of the substrate and configured to emit light on at least one optical wavelength band, and at least one lens disposed on an out-light side of the at least one light emitting component, where each lens corresponds to at least one light emitting component, and each lens is capable of reducing a divergence angle of light emitted by the at least one light emitting component corresponding to the lens.

Abstract: There is described a method for calculating a patient-specific hemodynamic parameter. The method comprises measuring at least one pressure measurement in an artery using an intravascular pressure measurement device, and taking at least one medical image of the artery from a medical imaging instrument, the at least one medical image of the artery being synchronous with the at least one pressure measurement. Both the pressure measurement and the medical image are fed to a computing system to calculate a flow from the at least one medical image, to calculate parameters of the artery from at least two artery pressure drops and corresponding flow components, and based on the flow and the parameters of the artery, to calculate a patient-specific hemodynamic parameter or a plurality thereof.

Abstract: Various embodiments of a monitoring system are disclosed. The monitoring system includes first and second sensors each adapted to detect a characteristic of a subject of the system and generate data representative of the characteristic of the subject, and a controller operatively connected to the first and second sensors. The controller is adapted to receive data representative of first and second characteristics of the subject from the first and second sensors, and determine statistics for first and second condition substates of the subject over a monitoring time period based upon the data received from the first and second sensors. The controller is further adapted to compare the statistics of the first and second condition substates, confirm the first condition substate if it is substantially similar to the second condition substate, and determine the statistics of an overall condition state of the subject based upon the confirmed first condition substate.

Abstract: Systems and methods for path length selected diffuse correlation spectroscopy (PLS-DCS) are disclosed. The systems and methods are suitable for measuring dynamics of a target medium. The systems and methods can utilize light sources having a coherence length that is shorter than a path length distribution of the target medium and can utilize a reference optical path to interferometrically detect PLS-DCS signals. The coherence length and reference path length can be selected to provide sensitivity to portions of the target medium that correspond to a desired path length distribution.

Abstract: A method for producing an image of a subject with a magnetic resonance imaging (MRI) comprises acquiring a first set of partial k-space data from the subject and generating a phase corrected image based on a phase correction factor and the first set of the partial k-space data. The method further includes transforming the phase corrected image into a second set of partial k-space data and reconstructing the image of the subject from the second set of the partial k-space data and a weighting function.

Abstract: The present disclosure relates to a method for determining electrical properties, EP, of a target volume (708) in an imaged subject (718). The method comprises: performing a first training (201) of a deep neural network, DNN, using a first training dataset, the first training dataset comprising training B1 field maps and corresponding first EP maps, the first training resulting in a pre-trained DNN configured for generating EP maps from B1 field maps; performing a second training (203) of the pre-trained DNN using conditional generative adversarial networks, GAN, and a second training dataset, wherein the pre-trained DNN is a generator of the conditional GAN, the second training dataset comprising measured B1 maps and second EP maps, the second training resulting in a trained DNN; receiving (205) an input B1 field map of the target volume and generating an EP map of the input B1 field map using the trained DNN.

Abstract: A system and method of magnetic particle imaging (MPI) are disclosed. The system and method use ultrasound to drive magnetic particles (such as nanoparticles) through a magnetic field gradient to generate a signal and map the magnetic particles' distribution or concentration.

Abstract: Sensor circuit device for measuring a bio-potential and/or a bio-impedance of a body, including a master circuit, and at least two active bi-electrodes connected to, and remotely powered by, the master circuit via single-wire first connector. The sensor circuit device further includes a single passive current electrode being connected to the master circuit via single-wire second connector. The sensor circuit device cooperates with a biological signal amplifier configured to measure a bio-potential and/or a bio-impedance. Each active bi-electrode is connectable to the biological signal amplifier via the first connector, such that a bio-potential of the body is measurable between the two active bi-electrodes when the active bi-electrodes and the single current electrode are in contact with a surface of the body.

Abstract: In various embodiments, a medical device comprises a urethral catheter including a distal portion two or more electrodes disposed on the distal portion; an impedance bridge coupled to the two or more electrodes; and a processor coupled to the impedance bridge. In various embodiments, a computer-implemented method for determining one or more tissue types at a location associated with a distal portion of a urethral catheter comprises recording, at one or more frequencies, one or more impedance measurements, wherein each impedance measurement is associated with two or more electrodes disposed on the distal portion of the urethral catheter; comparing the one or more impedance measurements to one or more characteristic impedances associated with one or more tissue types; and determining, based on the one or more impedance measurements and the one or more characteristic impedances, one or more tissue types at a location associated with the distal portion.

Abstract: Systems and methods for determining a contact angle of a catheter relative to tissue are provided. In one embodiment, a system includes a catheter with three or more electrodes, and a processor circuit in communication with the catheter. The processor circuit controls the three or more electrodes to emit a plurality of electrical voltages and to measure the plurality of electrical voltages. Based on the measured electrical voltages, the processor circuit calculates a first interelectrode impedance and a second interelectrode impedance. The processor circuit calculates, for each of a plurality of hypothetical i.e. model angles, a first hypothetical i.e. model contact force and a second hypothetical i.e. model contact force based on the first and second interelectrode impedances. The processor circuit determines and outputs the contact angle of the catheter based on a comparison of the first and second model contact forces calculated for each of the plurality of model angles.

Abstract: Some examples of the disclosure include applications, treatment-monitoring systems and computing devices configured with the applications, and computer-implemented methods to aid user monitoring of disordered-breathing and treatment.

Abstract: A system for monitoring a person may include a person-worn sensor device including at least one sensor (e.g., at least one accelerometer, magnetometer, altimeter, etc.) configured to collect sensor data and a processor to process data from the person-worn sensor device. The processor may be configured to determine or access an orientation of a physical support apparatus (e.g., bed, table, wheelchair, chair, sofa, or other structure for supporting the person), receive sensor data collected by the person-worn sensor device, calculate an orientation of the person relative to the physical support apparatus based on (a) the orientation of the physical support apparatus and (b) the sensor data collected by the person-worn sensor device, and identify, based on the determined orientation of the person relative to the physical support apparatus, a physical support apparatus exit condition indicating an occurrence or anticipated occurrence of the person exiting the physical support apparatus.

Abstract: Disclosed are systems and methods for classifying body movements, including gestures and activities of daily living. This may include preprocessing data output from an accelerometer and gyroscope into features that are input into a movement classifier. In some examples, the disclosed technology may utilize user confirmed labels of movements to improve the accuracy of the movement classifiers. This may include providing a notification to a user when a movement classifier determines a particular movement is detected that requests confirmation of the movement label.

Abstract: Disclosed are a method and system for monitoring a human movement posture, a human posture monitor, a storage medium and a processor. The monitoring method includes: receiving a microwave detection signal, wherein the microwave detection signal is a detection signal obtained after microwave scanning is conducted on a target region (S102); determining whether a current movement posture of a preset person in the target region is in a range of dangerous postures according to the microwave detection signal, wherein the current movement posture is an action form of the preset person at a position at a current time point (S104); and sending out an alarm signal when the current movement posture of the preset person in the target region is in the range of dangerous postures (S106).

Abstract: Sensors that detect an analyte via spectroscopic techniques using non-optical frequencies such as in the radio or microwave frequency range of the electromagnetic spectrum or optical frequencies in the visible range of the electromagnetic spectrum. An analyte sensor described herein includes a detector array having at least one transmit element and at least one receive element. The transmit element and the receive element can be antennas or light emitting elements such as light emitting diodes. The sensor is controlled to implement first and second frequency sweeps and the frequency sweeps have at least one overlapping range of frequencies where the operation times are the same between the first and second frequency sweeps.

Abstract: An optical core-shell microfibrous textile incorporates single-walled carbon nanotubes (SWCNTs) for the real-time optical monitoring of hydrogen peroxide concentrations and other biochemicals in in vitro wounds. The environmentally sensitive and non-photo-bleachable fluorescence of SWCNTs enable continuous analyte monitoring without a decay in signal over time. The microfibrous textiles spatially resolve chemical indicator concentrations using a camera and are integrated into commercial wound bandages without significant degradation in their optical properties.

Abstract: The present disclosure relates to noninvasive methods, devices, and systems for measuring various blood constituents or analytes, such as glucose. In an embodiment, a light source comprises LEDs and super-luminescent LEDs. The light source emits light at at least wavelengths of about 1610 nm, about 1640 nm, and about 1665 nm. In an embodiment, the detector comprises a plurality of photodetectors arranged in a special geometry comprising one of a substantially linear substantially equal spaced geometry, a substantially linear substantially non-equal spaced geometry, and a substantially grid geometry.

Abstract: A sensor component for use in a system for measuring concentration of analytes in fluid in a fluid line comprises one or more sensing elements having an optical property that varies with the concentration of the analytes, and engages with the fluid line such that the sensing elements are exposed to the fluid. The sensor component comprises a connector connecting to one or more optical waveguides, and transmits light between the waveguides and the sensing elements. The sensor component comprises one or more of a sampling port configured to provide fluidic access to the fluid line, a data storage medium storing data representing information about the sensor component, and a reflective element. Where it comprises a reflective element, the sensor component transmits light between the waveguides and the reflective element on a separate optical path from an optical path between the waveguides and the sensing elements.

Abstract: An example medical device includes an optical sensor, processing circuitry, an antenna, and a power source. The optical sensor includes a light source; a reference optical beacon having a first fluorophore that emits a first fluorescence proportional to a first concentration of a substance proximate the beacon; a test optical beacon having a reagent substrate that reacts with an analyte to produce the substance and a second fluorophore that emits a second fluorescence proportional to a second concentration of the substance proximate the test beacon; and a photodetector to detect the first and second fluorescence. The processing circuitry determines a difference between the first and second fluorescence, which is indicative of the concentration of the analyte. The antenna and power source enable the medical device to operate completely within a biological system for continuous analyte monitoring.

Abstract: Sensing and infusion devices are described. In one embodiment, a sensing and infusion device may include an implantable segment having a sensor. The sensing and infusion device may also include a catheter, and a sensor channel may be formed in the catheter. The sensor channel may be configured to retain at least a portion of the implantable segment.