Abstract: The present invention relates to heterotandem bicyclic peptide complexes which comprise a first peptide ligand, which binds to a component present on an immune cell, conjugated via a linker to a second peptide ligand, which binds to a component present on a cancer cell. The invention also relates to the use of said heterotandem bicyclic peptide complexes in preventing, suppressing or treating cancer.

Abstract: Devices, systems, and methods used to seal a treatment area to prevent embolic agents from migrating are described. The concept has particular benefit in allowing liquid embolic to be used with a variety of intravascular therapeutic applications, including for occluding aneurysms and arteriovenous malformations in the neurovasculature.

Abstract: A fabrication method of a surface acoustic wave (SAW) filter, includes: obtaining a piezoelectric substrate; forming a back electrode on a first portion of the piezoelectric substrate; forming a sacrificial layer on the first portion of the piezoelectric substrate, covering the back electrode; forming a first dielectric layer on the first portion of the piezoelectric substrate, covering the sacrificial layer; bonding a bottom substrate to the first dielectric layer; removing a second portion of the piezoelectric substrate to expose the first portion of the piezoelectric substrate, the first portion of the piezoelectric substrate constituting a piezoelectric layer; forming one or more release holes through the piezoelectric layer; forming an interdigital transducer (IDT) on the piezoelectric layer; and etching and releasing the sacrificial layer via the one or more release holes to form a lower cavity exposing the back electrode.

Abstract: Disclosed are embodiments of microstrip and substrate integrated waveguide circulators/isolators which can be integrated with a substrate. This composite structure can serve as a platform for other components, allowing for improved miniaturization of components. Embodiments of the disclosure can be particular advantageous in the high frequency ranges, such as above 1.8 GHz or above 3 GHz, which allows devices to be used in the 5G space.

Abstract: A radar system for surroundings detection of a motor vehicle. The radar system includes an antenna for sending and/or receiving radar signals, a circuit board including at least one high-frequency component and an element for sending and/or receiving high-frequency signals. At least one fastening element is situated on/at the circuit board. The antenna includes at least one connecting element. The connecting element interacts with the fastening element in such a way that the antenna is fastenable and at the same time positionable on the circuit board by being pushed onto the at least one fastening element.

Abstract: A fluid analysis simulation apparatus based on smoothed particle hydrodynamics (SPH) includes an input unit that receives data about a plurality of particles for fluid analysis simulation, a measurement space setting unit that sets a measurement space where a water level is to be measured in a space where the plurality of particles exists, a sampling space generation unit that divides the measurement space into a plurality of sampling spaces formed in a height direction of the measurement space, and a water level measurement unit that measures a water level in the measurement space based on a height of a particle included in each sampling space.

Abstract: The present disclosure relates to flexible energy absorbing systems and body armor, helmets and protective garments incorporating flexible energy absorbing systems. A flexible energy absorbing system may comprise a first plurality of cells having a first re-entrant geometry and a second plurality of cells having a second, different geometry. The first plurality of cells and the second plurality of cells may comprise an elastomeric material.

Abstract: A horizontally fed disk grinding system includes a tray coupled to a trailer for receiving bulk material. The system further includes a grind hub coupled to the trailer and a cutter disk coupled to the grind hub. The grind hub is structured to rotate about a grind hub axis and the cutter disk is structured to rotate about a cutter disk axis and about the grind hub axis. A grind ring is coupled to the trailer and is structured to slide to engage the grind hub during use. A plurality of plates are coupled to the tray and structured to oscillate to feed material from the tray to the grind hub and the cutter disk, where the material is reduced to particulate form. The grind hub further includes an outlet and a conveyor rotatably coupled to the trailer to convey the particulate material away from the outlet to a selected location.

Abstract: Doors on a vehicle may be controlled by a door positioning system that moves the doors freely and fluidly relative to the body of the vehicle. The doors may include front and rear doors on each side of the vehicle. The door positioning system may control the movement and positioning of each door using a door mechanism coupled between the door and the body of the vehicle. The door positioning system may determine a position or path of motion for each door based on sensor data and user input. The door positioning system may issue corresponding control signals to actuators in the door mechanism to position the door accordingly. For example, the front door may slide open at an angle to accommodate an angled tire. Front and rear doors may open in opposite directions to create a large, unobstructed space for passengers to enter and exit the vehicle.

Abstract: Disclosed in this application are a method for embedding a watermark in video data and apparatus, a method for extracting a watermark in video data and apparatus, a device, and a storage medium. The method for embedding the watermark includes: acquiring a target image frame in video data; performing time-frequency transformation on the target image frame to obtain target frequency domain data, the target frequency domain data comprising a matrix formed by frequency domain coefficients; changing the frequency domain coefficients in the target frequency domain data according to watermark data to obtain watermarked frequency domain data; performing inverse time-frequency transformation on the watermarked frequency domain data to obtain a watermarked image frame; and synthesizing watermarked video data according to the watermarked image frame.

Abstract: The present invention relates to the use of a lubricating composition for lubricating gear, wherein the lubricating composition comprises: at least a base oil; and at least a Molybdenum or Tungsten chalcogenide nanoobject having an object size ranging from 0.

Abstract: An information processing apparatus includes a first printer driver configured to generate first print data to be transmitted to an image forming apparatus according to a predetermined protocol and a second printer driver configured to generate second print data to be transmitted to a server system according to the predetermined protocol. The information processing apparatus further includes a display unit configured to display a first screen in a case where first information for transmitting the first print data is selected, and to display a second screen in a case where second information for transmitting the second print data is selected, and a transmission unit configured to transmit the first print data or the second print data.

Abstract: A magnetic sensor device includes at least one magnetic sensor and a support. A center of gravity of an element layout area of the at least one magnetic sensor is deviated from a center of gravity of a reference plane of the support. The at least one magnetic sensor includes four resistor sections constituted by a plurality of magnetoresistive elements. Magnetization of a free layer in each of two of the resistor sections includes a component in a third magnetization direction. The magnetization of a free layer in each of the other two resistor sections includes a component in a fourth magnetization direction opposite to the third magnetization direction.

Abstract: The present invention relates to oncolytic vaccinia viruses which have been modified to promote anti-tumor immunity and/or reduce host immunity and/or antibody response against the virus. It is based, at least in part, on the discovery that oncolytic vaccinia virus (i) bearing a genome deletion of a gene that reduces T cell immunity (interleukin-18 binding protein); (ii) treated with a sialidase enzyme which is believed to reduce TLR2 activation and therefore the antibody response; (iii) carrying a gene that enhances cytotoxic T lymphocyte induction (e.g., TRIF) and/or (iv) reduces tumor myeloid-derived suppressor cells by reducing prostaglandin E2 reduces tumor growth. Accordingly, the present invention provides for immunooncolytic vaccinia viruses and methods of using them in the treatment of cancers.

Abstract: Provided are bispecific antibodies against CD3 and EGFR, the nucleic acid molecules encoding the antibodies, expression vectors and host cells used for the expression of the antibodies. The antibodies provide a potent agent for the treatment of CD3-related and/or EGFR-related diseases via modulating immune functions.

Abstract: A calling system for a personal watercraft includes processing circuitry. The processing circuitry is configured to: obtain a specific state signal indicating that the personal watercraft is in a given specific state; and wirelessly transmit a calling signal based on the specific state signal.

Abstract: A modular spinal fixation system for securing an elongate rod to a bone of a patient includes a plurality of bone anchors, each having a universal shank head and an anchor portion opposite the universal shank head configured for fixation to the bone. The system further includes a plurality of pivoting and non-pivoting receiver sub-assemblies, with each receiver sub-assembly including a receiver having an upper portion defining a channel configured to receive the elongate rod and a base defining a lower portion of a central bore communicating with a bottom surface of the receiver through a bottom opening, and one of a shank head-engaging retainer or a rod-engaging insert positioned within the central bore.

Abstract: An aircraft flooring system is provided, made up of a low-weight carpet tile which functions both as a moisture barrier and as the loop part of a hook-and-loop system, for coupling to a hook part of a hook-and-loop system, which is bound to an aircraft floor. Specifically, a barrier backing within the carpet tile, comprising a nonwoven fabric portion, is able to act as the moisture barrier and the loop part, which allows for coupling of the carpet tile with the floor, without the need to add additional loops to the carpet tile, thereby realizing savings in material cost and weight.

Abstract: In some examples, a system includes a glucose sensor configured to generate a signal indicative of a blood glucose level of a patient, a medical device configured to deliver insulin to the patient, a peritoneal dialysis (PD) device, and control circuitry. The control circuitry is configured to control the PD device to deliver PD therapy to a patient during a PD cycle, determine a blood glucose level of the patient during the PD cycle based on a signal from the glucose sensor, determine that the blood glucose level is greater than or equal to a predetermined blood glucose level threshold, and control the medical device to deliver insulin to the patient in response to determining the blood glucose level is greater than or equal to the predetermined blood glucose level threshold.

Abstract: Apparatus for measuring the profile of a wellbore includes a cylindrical body having first and second ends threaded for connection in line with a drill string. A passage extends through the body between the first and second ends. A plurality of arms are pivotally coupled on an outer surface of the cylindrical body. Each of the arms is biased to pivot so as to move a free end of the arm to move radially away from the outer surface of the body. The plurality of arms are angularly spaced apart around the cylindrical body and arranged in a plurality of tiers. Each of the tiers comprises three or more of the arms. The tiers are spaced apart axially from one another along the cylindrical body. Sensors are operable to directly or indirectly measure radial extension of each of the arms from the cylindrical body. A holding mechanism is operable to hold the arms in a retracted configuration and to selectively release the arms to pivot away from the cylindrical body.

Abstract: A control system may receive a first plurality of measurements indicative of respective joint angles corresponding to a plurality of sensors connected to a robot. The robot may include a body and a plurality of jointed limbs connected to the body associated with respective properties. The control system may also receive a body orientation measurement indicative of an orientation of the body of the robot. The control system may further determine a relationship between the first plurality of measurements and the body orientation measurement based on the properties associated with the jointed limbs of the robot. Additionally, the control system may estimate an aggregate orientation of the robot based on the first plurality of measurements, the body orientation measurement, and the determined relationship. Further, the control system may provide instructions to control at least one jointed limb of the robot based on the estimated aggregate orientation of the robot.

Abstract: A method for providing an animated art experience to a user includes a user device receiving an image of an art piece selected by the user. The user device obtains information about the art piece. The user device presents a three-dimensional (3D) animated image that corresponds with the selected art image. Upon receiving an action by the user caused by a rotation or tilt of the user device, the user device provides a depth perspective view in correlation with the action and associated viewer angle of the art image such that further portions of the art image become visible. A background and a foreground of the image appear to move naturally as actions and associated viewer angles change.

Abstract: A method for visualizing multi-antigen binding capabilities of a set of clonotype groups. Clonotype data that identifies a clonotype group derived from an immune cell sequence dataset (e.g., single cell or spatial dataset) is obtained. A set of interactions for the clonotype group is identified. An interaction in the set of interactions is between a set of cells in the clonotype group and a plurality of antigens in which each cell of the set of cells binds to the plurality of antigens. A binding diagram is generated for the clonotype group based on the set of interactions that has been identified. The binding diagram includes a set of interaction representations that visually represents the set of interactions for the clonotype group. An interaction representation in the set of interaction representations visually relates the plurality of antigens and visually indicates a number of cells in the set of cells that bind to the plurality of antigens.

Abstract: One or more electrical components may be incorporated into a fabric seam. The fabric seam may join two pieces of material in a fabric item or may form the border of a fabric item. The fabric seam may include first and second fabric portions with one or more conductive strands extending between the first and second fabric portions. An electrical component may be coupled to the conductive strand. The fabric seam may have one or more side pockets for capturing the edge of a material such as a piece of fabric. The fabric seam may have gaps that allow conductive strands within the fabric seam to branch off in different directions. Openings may be incorporated in the fabric seam to allow air or light to pass through and/or to form a window for an electrical component in the fabric seam.

Abstract: The DCI format at least indicates a set of interlaces if the DCI format indicates a set of RB-sets, resource blocks for the PUSCH are given based on an intersection of the set of the interlaces and the set of the RB-sets, and if the DCI format doesn't indicate the set of the RB-sets, the resource blocks for the PUSCH are given based on an intersection of the set of the interlaces and a pre-determined set of RB-sets where the pre-determined set includes one RB-set which corresponds to one downlink RB set in which the DCI format is received.

Abstract: A helmet with an adjustable helmet shell is provided for use in sports including baseball and softball. The helmet shell is expandable and contractable to fit a variety of head shapes and sizes, and hairstyles. The helmet shell may be a single, molded piece or it may include a base member and a flap member. Gaps or slots may be located between flexible side portions and a flexible rear portion of the helmet shell. The slots facilitate outward deflection of the side portions and the rear portion when the helmet is donned. The helmet shell may be biased toward a smaller size such that once the helmet shell is expanded by the force of a wearer's head, it contracts to fit snugly and securely.

Abstract: Methods, apparatuses, and systems associated with aerosol collection devices (such as, but not limited to, breath-aerosol collector devices, breathalyzers) are provided.

Abstract: An embodiment hook assembly for a door curtain to be installed on a door panel of a vehicle, the hook assembly includes a hook body installed to penetrate a through hole formed in the door panel, and a hook pin having an upper end hinge-connected to an upper portion of the hook body, wherein in a state in which an upper portion of the hook pin is completely inserted into the hook body, a part of the hook body is in an opened state and the hook body is locked to a circumference of the through hole such that the hook body is fastened to the through hole.

Abstract: A medical scope device such as an endoscope is produced using a cast aluminum process including a molten casting aluminum alloy including a maximum of 0.2 - 0.3% Si and at least 5% Zn. The process includes providing an investment casting mold, casting the aluminum alloy in the mold to create a component and removing the mold from the component, post-machining the component to meet a desired specification, and after post-machining the component, performing surface finishing, such as centrifugal barrel finishing (CBF) sufficient to remove impurities on casting surfaces by 2 - 3 mils, then coating the component with a micro-crystalline aluminum anodic coating of at least 0.5 mil thickness. A medical scope and product-by-process is also provided employing such techniques.

Abstract: A hydraulic device is disclosed. The hydraulic device can include a rotor, a plurality of vanes and a ring. The ring can include a suction cavity and a pressure cavity. The suction cavity and pressure cavity can be configured for ingress and egress of a hydraulic fluid through the ring. The ring can include a suction port defined entirely by the ring and in fluid communication with the suction cavity. The suction port can be configured to receive hydraulic fluid from a first region between the ring and the rotor. The ring can include a pressure port defined entirely by the ring and in fluid communication with the pressure cavity. The pressure port can be configured to allow for passage of the hydraulic fluid from the pressure cavity to a second region between the ring and the rotor.

Abstract: In one embodiment, a device obtains a first set of measurements of a path metric for a path in a network that are measured using periodic probing of the path. The device obtains a second set of measurements of the path metric for the path that are measured using fine-grained probing of the path at a higher frequency than that of the periodic probing. The device generates a predictive model that predicts values of the path metric, based on the first set of measurements and on the second set of measurements. The device causes, based on a value of the path metric predicted by the predictive model, traffic to be rerouted from the path to another path in the network.

Abstract: Provided is a process including: obtaining a first set of one or more images generated via an optical gas imaging (OGI) camera and a second set of one or more images generated via a second camera, wherein the first set and the second set correspond to a first location of a plurality of locations in a facility; classifying, via a convolutional neural network (CNN), the first set of one or more images according to whether the one or more images depict a gas leak; and storing a result of classifying the first set in memory.

Abstract: Systems and methods for gesture-based control are disclosed. In some embodiments, a system may include a wearable device configured to obtain physiological data and wrist location data. The system may be configured to detect a first gesture and transition to an object control state in which changes in the wrist location data and/or the physiological data are configured to control a movement of the object. In the object control state, the system may be configured to detect a first motion of a body part, generate a first command to move the object in a first command direction, detect a second motion of the body part, and generate a command to move the object in a second command direction. The system may detect a second gesture indicating an intention to cease control of the object, and transition out of the object control state.

Abstract: A packoff for a wellhead includes a body configured to be positioned in an annulus between the wellhead and an inner tubular above a casing hanger supported in the wellhead, the body including a bore and a lower end, the bore and the lower end being configured to be positioned at least partially around the inner tubular. The lower end is configured to be spaced apart from the casing hanger. The packoff also includes a first load shoulder member configured to be removably connected to the lower end of the body and to engage a surface of the casing hanger so as to form a seal therewith.

Abstract: An integrated fluid ejection and spectroscopic sensing system may include a fluid ejector to eject a droplet of fluid through an ejection orifice towards a deposition site, a sensor array, a dispersive element to project light onto the sensor array. The dispersive element, the sensor and the fluid ejector are joined as part of an integrated unit.

Abstract: An improved blade assembly is provided for use in a cooking appliance such as a blender or a food processor. The bottom blade portions of the blade assembly include a geometry that provides an angled, sharpened portion on wing portions that extend downwardly from the bottom blade. The bottom blade's geometry, including the sharpened portions, help rotate the material so that it is blended upwardly to help prevent food from getting stuck in the void below the bottom blade, thus improving the blade's efficiency.

Abstract: The present disclosure discloses a proximity-based secure communication system and method for digital transactions. The system comprises: a slave terminal with a near field communication (NFC) radio frequency communication channel, wherein the slave terminal remains in the listening mode in the NFC radio frequency communication channel; and a master electronic device with an NFC radio frequency communication channel. The slave terminal is configured to send an Answer-to-Reset (ATR) to the master electronic device when, by proximity, the slave terminal detects the activation of the NFC radio frequency channel. The slave terminal and the master electronic device exchange Application Protocol Data Unit (APDU) commands that represent a digital transaction by means of the NFC radio frequency channel, such that the master electronic device sends request APDU commands to the slave terminal, and the master electronic device receives reply APDU commands from the slave terminal.

Abstract: A method for collecting prone position data of a human body is disclosed. The method includes: collecting weight data, back contour data and height data of a standing subject; receiving the weight data, the back contour data, and the height data, pre-preprocessing such data, and sending the pre-processed pre-processing data to a simulated bed by a processing center; receiving the pre-processed data and adjusting an initial pressure of a plurality of elastic columns of the simulated bed according to the pre-processed data by the simulated bed; causing the subject to lie on the adjusted simulated bed and further adjusting the simulated bed according to a subjective description of the subject until the simulated bed is suitable for the subject; collecting adjustment data of the simulated bed suitable for the subject by the processing center. A system for collecting prone position data of a human body is also disclosed.

Abstract: The invention relates to a charging contact unit for a vehicle, for integrating beneath a road surface, with a charging contact element carrier head designed to interact with a contact device on the lower side of a vehicle, the contact making and the contact separation being carried out by a relative movement of the charging contact element carrier head and the contact device in a contacting direction, the charging contact element carrier head being movable inside the charging contact unit and/or rotatable or pivotable about the contacting direction in order to compare incorrect positioning in either one or a plurality of directions extending transversely to the contacting direction. The invention also relates to a contact system and a road covering.

Abstract: Systems, computer program products, and methods are described herein for machine learning process/model building using fuzzying techniques. The present invention is configured to determine one or more process components associated with a workflow process of an application; retrieve data from each of the one or more process components; initiate a data fuzzying engine to introduce one or more adversarial noise components on the data retrieved from each of the one or more process components; receive one or more instances of exposure for the application from each of the one or more process components in response to introducing adversarial noise on the data retrieved from each of the one or more process components; and automatically initiate one or more mitigation actions in response to receiving the one or more instances of exposure for the application from each of the one or more process components.

Abstract: Presented herein is an air vent including a plate, and a non-uniform array of openings extending through a thickness of the plate. The non-uniform array of openings arranged to admit a flow of cooling air through the plate. The plate and the non-uniform array of openings are arranged to attenuate electromagnetic interference (EMI) emitted through the plate.

Abstract: A light emitting diode of an embodiment includes a first electrode, a second electrode, and at least one functional layer between the first electrode and the second electrode, wherein the at least one functional layer includes at least one selected from among a polycyclic compound represented by Formula 1 and a compound represented by Formula E-1.

Abstract: The present application provides a semiconductor structure and a manufacturing method thereof. The manufacturing method includes: providing a stacked structure, the stacked structure includes a first chip and a second chip; forming a through silicon via (TSV) in the stacked structure, the TSV includes a first part and a second part communicating with the first part, a sidewall of the first part is a vertical sidewall, and a sidewall of the second part is an inclined sidewall; forming an insulating layer on the sidewall of the first part; and forming a conductive layer in the TSV.

Abstract: A non-threaded, one-touch connection device for connecting reinforcing bars includes a pair of coupler bodies fastened together by a connector and each of the coupler bodies having a hollow portion for receiving the reinforcing bar. An inner diameter of the coupler body gradually increases from an entrance of the coupler body to an end opposite to the entrance. A lock is placed in the coupler body. The lock includes slits and wall parts partially separated by the slits. The lock further includes a breaking disc configured to break away from the lock. An elastic member is placed between the connector and the lock to apply an elastic force to move the lock toward the entrance when the reinforcing bar is fastened to the lock. The coupler body further has a checking hole to allow concrete to flow in and out.

Abstract: The invention described herein provides a method and apparatus to realize incorporation of Beryllium followed by activation to realize p-type materials of lower resistivity than is possible with Magnesium. Lower contact resistances and more effective electron confinement results from the higher hole concentrations made possible with this invention. The result is a higher efficiency GaN-based LED with higher current handling capability resulting in a brighter device of the same area.

Abstract: Described herein are apparatuses and methods for conditioning particles. In some embodiments, the apparatuses and methods are configured for first-in-first-out transit of particles through a chamber containing a conditioning fluid.

Abstract: A system for selecting a preferred intraocular lens for implantation into an eye includes a controller having a processor and a tangible, non-transitory memory. The controller is configured to obtain diagnostic data of the eye, and obtain historical data composed of historical sets of patient data. The controller is configured to analyze individual risk factors based on the diagnostic data and obtain a weighted combination of the individual risk factors. A respective satisfaction metric for the plurality of intraocular lenses is generated based on the historical data. A preferred intraocular lens may be selected based in part on the respective satisfaction metric and the weighted combination. A visual simulation for each of the plurality of intraocular lenses may be performed, based in part on the diagnostic data. The visual simulation may incorporate an impact of the tear film data.

Abstract: Method and system for providing carbon offset sources. For example, the method includes determining an amount of total carbon emission of a user, receiving a desired percentage of carbon offset, determining a total number of carbon offset units corresponding to a predetermined carbon offset source, providing multiple carbon offset sources, receiving a respective number of carbon offset units corresponding to the predetermined carbon offset source for each of the multiple carbon offset sources, determining a respective cost for each of the multiple carbon offset sources, and providing a total amount of cost based upon the respective cost for each of the multiple carbon offset sources, where a total of the respective number of carbon offset units is equal to the total number of carbon offset units.

Abstract: Disclosed herein are a method and apparatus for encoding/decoding a deep neural network. According to the present disclosure, the method for decoding a deep neural network may include: in a plurality of layers of the deep neural network, entropy decoding quantization information for a current layer; performing dequantization on the current layer; and obtaining a plurality of layers of the deep neural network. At least one of global quantization and local quantization is performed on the current layer.

Abstract: The A method of augmenting a view of a real-world environment with a view of a volumetric video object on a user device is disclosed . The method includes determining a current pose information (CPI) indicating a current pose of the view of the real-world environment and a desired pose of the volumetric video object in the real-world environment. The method further includes sending the CPI to a remote server. The method further includes receiving a rendered view of the volumetric video object that has been rendered in accordance with the CPI from the remote server. The method also includes augmenting the view of the real-world environment by at least mapping the rendered view of the volumetric video object onto a planar mapping surface arranged according to the desired position of the volumetric video object.