Abstract: An OCT (Optical Coherence Tomography) handheld device is provided comprising: a housing configured for handheld OCT scanning during a surgical procedure, the housing comprising an OCT scanning end and a proximal end opposite the OCT scanning end; an OCT scanning device inside the housing, the OCT scanning device configured for one or more of OCT polarized scanning and Doppler OCT scanning from the OCT scanning end, the OCT scanning device further configured to receive and convey OCT light between the proximal end and an OCT analysing system; and a tip extending from the OCT scanning end, the tip being removably attached to the OCT scanning end, the tip configured to receive and collect the OCT light therethrough. The OCT handheld device is configured to be removably draped around the tip, for use in the surgical procedure.

Abstract: The present invention relates to a real-time parathyroid imaging apparatus including: a light source including an excitation filter capable of exciting parathyroid glands; and a camera including an image sensor and an emission filter of which a transmissivity ratio between a visible light region and a near-infrared emission wavelength region is N:1 (here, N<1). Through the present invention, a system may be implemented whereby a surgeon may acquire, in real-time during an operation, an autofluorescence image of the parathyroid glands by using a near-infrared light source, and an auto focus function may be used, and visible light and near-infrared autofluorescence images may be simultaneously fused and acquired without having to turn off the lights in an operating room.

Abstract: A catheter system for optical coherence tomography includes an elongate catheter body, an optical fiber in the elongate catheter body, and an anamorphic lens assembly coupled with a distal end of the optical fiber. The optical fiber and the lens assembly are together configured to provide a common path for optical radiation reflected from a target and from a reference interface between the distal end of the optical fiber and the lens assembly.

Abstract: Certain aspects of the present disclosure provide methods and apparatus for managing an esophagus of a subject during a medical procedure, such as cardiac tissue ablation or bronchial tissue ablation. Managing the esophagus may include displacing the esophagus, imaging the esophagus, and/or measuring temperature at one or more locations inside the esophagus. One example esophageal management system generally includes a tube configured for insertion through a mouth and into the esophagus of the subject. The tube generally includes a first port located at a proximal end of the tube and in fluid communication with a distal portion of the tube via a first path, a second port located at the proximal end of the tube, and a third port located between the proximal end of the tube and a distal end of the tube and in fluid communication with the second port via a second path.

Abstract: A method of monitoring a patient's foot forms a thermogram of the sole of at least one foot of the patient, and determines whether the thermogram presents at least one of a plurality of prescribed patterns. The method also compares the thermogram against a prior thermogram of the same foot, and produces output information indicating the emergence of an ulcer on a given portion on the at least one foot as a function of 1) whether the thermogram is determined to present the at least one pattern, and 2) the comparison with the prior thermogram, which shows non-ulcerated tissue at the given location.

Abstract: [Subject] Non-invasive method for estimating blood pressure without a cuff and a device for the blood pressure estimation [Resolution means] Systolic blood pressure (EBP) is estimated according to EBP=?1·P1+?2·P2+?0 (?1, ?2, and ?0 are coefficients) where parameter P1, which is related to pulse transit time (PTT), and parameter P2, which is related to stroke volume based on pulse waves, are variables.

Abstract: There is provided a technique configured to measure blood pressure with high accuracy. A pulse wave is acquired from each of a plurality of regions on a body surface of a subject, at least two regions are selected from among the plurality of regions in accordance with signal quality of the acquired pulse wave of each region, and blood pressure information is calculated with reference to pulse wave propagation information indicating pulse wave propagation between the at least two regions selected.

Abstract: A blood pressure measuring apparatus for measuring blood pressure of a subject using a cuff attached to the subject includes a processor and a memory to store instructions that are readable by the processor. As the instructions are executed by the processor, the apparatus generates a pulsation signal of the subject while increasing an inner pressure of the cuff; generates a first-order differential signal by differentiating the pulsation signal. The apparatus then detects an inappropriate attachment state of the cuff based on at least one of: a bottom value of the first-order differential signal; a relationship between a peak value and the bottom value of the first-order differential signal; an amplitude amount of the first-order differential signal including the bottom value in a unit time; and a relationship between the amplitude amount and an amplitude amount of the first-order differential signal including the peak value in a unit time.

Abstract: The present disclosure generally relates to wearable devices and methods for measuring a photoplethysmographic (PPG) signal. The wearable devices and methods described herein are capable of obtaining PPG signals by employing a PPG sensor array configured to receive light at angles associated with a high perfusion index. Viewing components may be coupled to the PPG sensor array to effect transmission of light at these preferential angles.

Abstract: Provided according to embodiments of the invention are methods of monitoring the direction of blood flow that include processing with a computer photoplethysmography (PPG) signal streams from a sensor array on a body site of the individual to determine the direction and/or velocity of the blood flow at the body site of the individual. In some embodiments, direction of the blood flow at the body site is determined by the phase difference between at least three PPG signal streams from the sensor array, wherein the at least three PPG signal streams are generated from emissions of the at least three emitters.

Abstract: The wrist-type body component measuring apparatus includes: a band configured to be worn on a wrist of a user; a first input electrode and a first output electrode disposed on an inside surface of the band and configured to be in contact with the wrist of the user; a second input electrode and a second output electrode disposed on an outside surface of the band; a measuring unit configured to apply a current to the first and second input electrodes and detect a voltage from the first and second output electrodes to measure a body impedance of the user; and an electrode converter configured to convert a disposition of the first and second input electrodes and the first and second output electrodes based on a determination of whether the band is worn on a left wrist or a right wrist of the user.

Abstract: Methods, devices, and systems for contactless cough detection and attribution are presented herein. Audio data may be received using a microphone. A cough may be identified as having occurred based on the received audio data. Radar data may be received indicative of reflected radio waves from a radar sensor. A state analysis process may be performed using the received radar data. The detected cough may be attributed to a particular user based at least in part on the state analysis process performed using the radar data.

Abstract: A method for operating an accessory device to capture calibration data. The method can include capturing an image of a portion of a user's body that includes the user's stoma and at least two reference locations, and storing distance scale information representative of a distance between the two reference locations. The method further includes processing the captured image, including: identifying the reference locations, identifying the stoma, and generating calibration data representative of one or more stoma parameters as a function of the identified reference locations, identified stoma and the distance scale information. The calibration data can be stored.

Abstract: A wearable device is provided. The wearable device includes at least one motion sensor operable to detect one or more motion signals, a processor coupled to the at least one motion sensor, one or more biological sensors coupled to the processor and operable to detect one or more biological indicators of a user, and a memory configured to store instructions executable by the processor. The instructions, when executed, are operable to: obtain at least one of the one or more biological indicators of the user; correlate the at least one biological indicators of the user with the detected one or more motion signals; and determine that a drink event is detected based on the correlation between the detected one or more motion signals and the at least one biological indicators.

Abstract: Described are methods and devices (100) for measuring a sweat property of skin (12) in response to at least one test material or component (172, 174, 176, 178). Embodiments of the device include a plurality of different sweat stimulation sites. The Sweat stimulation sites may include one or more sweat stimulant reservoirs (142, 144, 146, 148) configured to deliver a sweat stimulant to the surface of the skin (12). Embodiments may also include at least one electrode (150, 152, 154, 156, 158) for measuring a sweat property or to iontophoretically deliver the sweat stimulant from the reservoir (142, 144, 146, 148). In embodiments, the sweat stimulant is selected from acetylcholine, carbachol, methacholine, bethanechol, muscarine, pilocarpine, oxotremorine, and combinations thereof.

Abstract: A method for determining a body fluid glucose level of a patient from a continuous signal of a glucose sensor element of a continuous body fluid glucose monitoring device in a data processing unit, comprising receiving measurement data representing a continuous sensor signal provided by a glucose sensor element of a continuous body fluid glucose monitoring device in the data processing unit, receiving calibration data representing a time-dependent zero-signal level of the glucose sensor element in the data processing unit, determining a body fluid glucose level by processing at least the measurement data and the calibration data in the data processing unit, the processing comprising subtraction of the time dependent zero-signal level from the continuous sensor signal, and providing result data indicative of the continuous body fluid glucose level in the processing unit; and a system for determining a body fluid glucose level of a patient.

Abstract: A apparatus for estimating concentration may include: a spectrum obtainer configured to obtain Raman spectra of an object; and a processor configured to extract, from the Raman spectra, at least one analyte spectrum related to an analyte and at least one non-analyte spectrum related to a biological component other than the analyte, and estimate concentration of the analyte based on a first area under a curve of the at least one analyte spectrum and a second area under a curve of the at least one non-analyte spectrum.

Abstract: A method for calibrating detectors of a self-contained, tissue oximetry device includes emitting light from a light source into a tissue phantom, detecting in a plurality of detectors the light emitted from the light source, subsequent to reflection from the tissue phantom, and generating a set of detector responses by the plurality of detectors based on detecting the light emitted from the light source. The method further includes determining a set of differences between the set of detector responses and a reflectance curve for the tissue phantom, and generating a set of calibration functions based on the set of differences. Each calibration function in the set of calibration functions is associated with a unique, light source-detector pair. The method further includes storing the set of calibration function in a memory of the self-contained, tissue oximetry device.

Abstract: This disclosure concerns a medical device and a method for its production, wherein the device comprises a cannula having an elongated hollow shaft and a sharp tip provided at a distal end of the shaft, wherein the shaft is formed as a bent part from a sheet material and confines an interior passage which has a lateral slit opening, and wherein the shaft has at least one longitudinal pre-bending channel provided in the sheet material, wherein the thickness of the sheet material is reduced along the pre-bending channel and a sidewall of the shaft is folded over the pre-bending channel.

Abstract: Analyte monitoring systems, devices, and methods associated with analyte monitoring devices, and devices incorporating the same are provided. Various graphical user interfaces (GUI) and navigation flows are provided for performing various features, activities, functions, etc., associated with the analyte monitoring device or system. Intuitive navigation is provided to enhance the interpretation of analyte measurements.

Abstract: A push-type blood collection needle includes a housing having an accommodating cavity therein, a rear cover and a needle body disposed in the accommodating cavity. The rear cover is movably disposed on the housing, and the rear cover has a supporting leg extending into the accommodating cavity. The needle body is provided with a rib. The accommodating cavity is internally provided with a projecting part that cooperates with and blocks the bottom of the rib. The supporting leg is provided with a stopper that cooperates with and blocks the side wall of the rib. And an elastic member is disposed between the needle body and the rear cover.

Abstract: Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.

Abstract: A measurement chamber that is essentially dome shaped and has a base area with a membrane and has at least two connection points fora fluid flow. The measurement chamber has two outer webs opposite each other, one of the webs engaging a clamping edge of a coupling element.

Abstract: The present invention relates to a physiological monitoring device. Some embodiments of the invention allow for long-term monitoring of physiological signals. Further embodiments may also allow for the monitoring of secondary signals such as motion.

Abstract: Provided is a cognitive impairment diagnosis method including: receiving an electroencephalogram signal of a user by a cognitive impairment diagnosis device; preprocessing the electroencephalogram signal by the cognitive impairment diagnosis device; extracting features, by the cognitive impairment diagnosis device, from the electroencephalogram signal by using a brain connectivity-based analysis method; and outputting cognitive impairment diagnosis information of the user by the cognitive impairment diagnosis device, on the basis of features having a causal relationship with the cognitive impairment diagnosis information, among the extracted features.

Abstract: The present invention refers to the field of cardiac electrophysiology (EP) and, more specifically, to image-guided radio frequency ablation and pacemaker placement procedures. For those procedures, it is proposed to display the overlaid 2D navigation motions of an interventional tool intraoperatively obtained from the same projection angle for tracking navigation motions of an interventional tool during an image-guided intervention procedure while being navigated through a patient's bifurcated coronary vessel or cardiac chambers anatomy in order to guide e.g. a cardiovascular catheter to a target structure or lesion in a cardiac vessel segment of the patient's coronary venous tree or to a region of interest within the myocard. In such a way, a dynamically enriched 2D reconstruction of the patient's anatomy is obtained while moving the interventional instrument.

Abstract: A non-transitory computer-readable medium stores instructions readable and executable by at least one electronic processor (20) to perform an atrial fibrillation (AF) detection method (100). The method includes: generating a time-frequency representation of an electrocardiogram (ECG) signal acquired over a time interval; processing the time-frequency representation using a neural network (NN) (32) to output probabilities for rhythms of a set of rhythms including at least atrial fibrillation; assigning a rhythm for the ECG signal based on the probabilities for the rhythms of the set of rhythms output by the neural network; and controlling a display device (24) to display the rhythm assigned to the ECG signal.

Abstract: A system and a method for identifying a patient with a threshold number of distinct ECG abnormalities. The system and the method include an ECG monitoring device; a server; a database; a network; a memory containing machine readable medium comprising a machine executable code having stored thereon instructions for identifying patients with a threshold number of distinct ECG abnormalities; and a processor coupled to the memory, the processor configured to execute the machine executable code to cause the processor to: receive an ECG data output from the ECG monitoring device; process the ECG data output to identify abnormalities in the ECG data; and analyze the abnormalities in the ECG data in order to output an indication of whether the patient has depressed LVEF, wherein the ECG monitoring device, the server, the database, the memory, and the processor are coupled to the network via communication links.

Abstract: An intracellular monitoring device (IMD) that fits completely inside a living cell, and causes no significant impairment, to a cell's normal biological processes. The IMD monitors a cell for its level of a biological substance (e.g., calcium ion concentration) of interest. If the biological substance reaches or exceeds a threshold, the IMD transmits an electromagnetic signal, received by an antenna outside the cell. Each IMD has its electromagnetic signal encoded with a unique frequency. Detection of the frequency components, in the signals received by an antenna, permits identification of the source IMD's. A high calcium ion concentration is indicative of a strongly-activated cerebral cortex neuron. Brain tissue is relatively transparent to near infrared, making it a good frequency band, for the electromagnetic signals from neuron-monitoring IMD's. The near infrared of each IMD can be produced by quantum dots, powered by bioelectric catalysis triggered by high calcium ion concentration.

Abstract: Instruments and methods for wide-field polarized imaging of the skin to determine an outer lesion margin objectively in vivo to provide guidance to a surgeon. Quantitative characterization of collagen structures in the skin can be used to determine the outer lesion margin or monitor skin treatment.

Abstract: An arrangement is provided for monitoring the plantar temperature of the foot having a platform with at least two multi-layer temperature sensitive pads that measure the temperature of a sole of a user's feet. The platform has a scanner for scanning the bottom of the user's feet that produces a digital image thereof. A printed circuit board supports remote connectivity to a mobile application that transmits the scanned digital image of the users' feet to the mobile application for storage and delivery to a physician. The arrangement includes the mobile application that provides a series of diagnostic questions and prompts to the user and is configured to transmit data including the scanned images of the user's feet to a physician.

Abstract: The present disclosure provides apparatuses and methods for measuring capacitance as an indication of susceptibility to the formation of a diabetic foot ulcer.

Abstract: An evaluation system including a hardware system for collecting real-time data for evaluating sleeping comfort performance of a bedding system is disclosed. The hardware system includes a thermal and moisture comfort measurement system, a thermal and moisture comfort control system, a biomechanical comfort control system, and a biomechanical comfort measurement system. The evaluation system also includes a computational system having a processor and a tactile database, and a portable device. The computational system is configured to receive and process the real-time data from the hardware system, and is communicatively connected to the portable device for transmitting real-time data for evaluating the bedding system and adjusting the hardware system.

Abstract: Devices, systems, and methods for delivering fluid therapy to a patient are disclosed herein. An exemplary method can comprise obtaining a urine output rate from a patient; causing a diuretic to be provided to the patient at a dosage rate, wherein the dosage rate is increased over a period of time such that the urine output rate increases to be above a predetermined threshold within the period of time; and causing a hydration fluid to be provided to the patient at a hydration rate. The hydration rate can be set based on the urine output rate to drive net fluid loss from the patient.

Abstract: An example method includes obtaining an image of a lead implanted in a patient, the lead including one or more electrodes positioned along a longitudinal axis of the lead and a plurality of orientation markers; determining, in the image, respective locations of the electrodes and respective locations of the orientation markers; obtaining a template model corresponding to the lead; determining a transform between the determined locations of the one or more electrodes and the plurality of orientation markers and locations of corresponding electrodes and orientation markers in the template model; and determining the rotational orientation of the lead based on the transform.

Abstract: A method includes determining that a portion of a force applied to a sensor system was applied to a non-inclusive region of the sensor system. An activation area of the non-inclusive region may be determined. A force distribution of the non-inclusive region may be determined. A corresponding force measurement of the non-inclusive region based on the activation area and the force distribution may be calculated.

Abstract: A physical area network for detecting head injuries described herein enables significantly improved cranial health monitoring and treatment by utilizing internal (in-body) mechanisms and information and external mechanisms and information.

Abstract: A method for obtaining a cycle of a physiological signal includes: a collection device for collecting a vibration signal of body movements; a processor for obtaining a physiological signal by processing the vibration signal; receiving a physiological signal value and a register value, comparing the physiological signal value with the register value, and reserving one of the physiological signal value and the register value; determining the physiological signal value having a corresponding time duration, reaching a given set time to be an extreme value, wherein the time duration is a time duration of the physiological signal value received is not exceeded; restarting the procedure and determining a next extreme value; obtaining the cycle of the physiological signal by processing the at least one extreme value; and displaying the cycle of the physiological signal in a display device.

Abstract: Systems, methods, and computer-readable media are provided for identification of patients having an elevated near-term risk of chronic kidney disease progression, including quantitatively predicting whether or not an elevated risk of progression of Stage 3 or Stage 4 chronic kidney disease is likely within a time interval of up to 36 months subsequent to computing the prediction. Based on the prediction, appropriate care providers may be notified so that the risk of CKD progression may be mitigated. In some embodiments, serial measurements are obtained of urine osmolality, and a challenge with an AVP V2 antagonist and serum sodium concentration is provided. From a time series based on the serial measurements, estimates of each variable's velocity and/or doubling-time may be determined. These values then may be combined via a multivariable mathematical model for providing a leading indicator of near-term future abnormalities in kidney function.

Abstract: An object of the present invention is to more appropriately extrapolate a sign of a state that may affect a movement of a user. A state extrapolation device according to the present invention includes a vital sign acquisition unit that acquires a vital sign of a user, and a sign detection unit that uses a learned model that has learned, as training data, sign data about the vital sign related to a predetermined physical condition abnormality, and detects a sign by determining whether or not the vital sign of the user corresponds to a sign of the predetermined physical condition abnormality.

Abstract: An overdose of opioids can cause the user to stop breathing, resulting in death. A physiological monitoring system monitors respiration based on oxygen saturation readings from a fingertip pulse oximeter in communication with a smart mobile device and sends opioid monitoring information from the smart mobile device to an opioid overdose monitoring service. The opioid overdose monitoring service notifies a first set of contacts when the opioid monitoring information indicates a non-distress stats and notifies a second set of contact when the opioid monitoring information indicates an overdose event. The notification can be a phone call or text message to a specified person, emergency personnel, or first responders, and can include the location of the smart mobile device. The smart mobile device can also include the location of the nearest treatment center having emergency medication used in treating opioid overdose, such as naloxone.

Abstract: An apparatus comprising a radiation source, coincident positron omission detectors configured to detect coincident positron annihilation emissions originating within a coordinate system, and a controller coupled to the radiation source and the coincident positron emission detectors, the controller configured to identify coincident positron annihilation emission paths intersecting one or more volumes in the coordinate system and align the radiation source along an identified coincident positron annihilation emission path.

Abstract: A system for imaging a breast includes a gantry and a tube head rotatably coupled thereto. An x-ray source is disposed within the tube head. A support arm is movably coupled to the gantry and includes a breast support platform. An x-ray detector is disposed within the breast support platform and a compression arm is movably coupled to the support arm. An opaque breast compression paddle is coupled to the compression arm. The breast support platform and the opaque compression paddle at least partially define a compression volume for compressing a breast and a camera is arranged to capture images of the compression volume. An image display is at least partially disposed on the system and is configured to display the images of the compression volume captured by the camera.

Abstract: A radiation shield assembly includes a shield configured to block radiation and a rail assembly configured to position the shield in between the radiation table and a radiation source. The shield is movable between a retracted position and an extended position along a length of the rail assembly. In the extended position, the shield extends along a portion of a radiation table and blocks radiation from the radiation source to the portion of the radiation table. In the retracted position, the shield exposes at least some of the portion of the radiation table to the radiation.

Abstract: A cannula and method include a shaft portion having a proximal end, a distal end, a longitudinal axis and a lumen extending from the proximal end to the oppositely disposed distal end along the longitudinal axis. A hub is attached to the proximal end of the shaft portion and includes a transverse portion, which extends transversely relative to the longitudinal axis of the shaft portion. An opaque marker is disposed on the transverse portion at a position corresponding to an expanded size of an expandable element such that the opaque marker indicates the expanded size in an imaging system image.

Abstract: Systems and methods for image-guided medical procedures use fluoroscopic 3D reconstructions to plan and navigate a percutaneously-inserted device such as a biopsy tool from an entry point to a target.

Abstract: The application relates to an X-ray imaging system (100) for dental X-ray imaging. The system comprises a controller, a rotating gantry (120), an X-ray source (124) for emitting X-rays, and an X-ray imaging detector (126) for receiving the X-rays from the source. The gantry comprises the source and detector (124, 126). The controller is configured to control the source to emit X-ray radiation and the detector for receiving the emitted radiation in order to acquire an X-ray image data. The system further comprises a depth information-producing camera (177), which is configured to produce a depth information, and a position information-producing component (183), which is configured to produce a position information, for acquiring at least a location data of the depth information-producing camera and detector during the irradiation, synchronously with the image data to be reconstructed.

Abstract: Provided is a novel medical image scanner gantry that includes at least one annular nozzle opening within the patient tunnel where the at least one annular nozzle opening directs a flow of pressurized air toward the back end of the patient tunnel which draws an amount of the ambient air into the patient tunnel to supplement the flow of pressurized air in the patient tunnel to help improve the patient's comfort.

Abstract: A medical imaging device, such as a computed tomography device and/or a magnetic resonance device, includes at least one movable component. The at least one movable component can include a patient couch, and the medical image device can further include an operating device for controlling the operation of the at least one component. The operating device can include a touch-sensitive and force-sensitive interface (e.g. touchscreen display) having at least one touch sensor and at least one force sensor that measure the strength of a touch.

Abstract: Provided is a 3D bone density and bone age calculation apparatus using an artificial intelligence-based rotation manner. The 3D bone density and bone age calculation apparatus includes a main body, and the main body includes a rotary drum including a drum shaft gear, an X-ray generator, an intensifying screen, and an image data capturer, a drum driver including a motor shaft gear connected to the drum shaft gear so as to rotate the rotary drum, a motor, support rollers and one of an origin sensor and an encoder, an outer case and an inner case, a front case and a rear case, a capturing holder, and a controller configured to select an image-captured position of the rotary drum, and configured to input a current age, sex and nutritional status of a patient, etc. The controller includes a display configured to display captured images and a diagram indicating bone age.