Abstract: A glass sheet of the present invention is characterized in that: the glass sheet has a refractive index nd of from 1.55 to 2.30; the glass sheet has an inclined surface in at least a part of an end surface; an angle formed by the inclined surface and a principal surface is from 5° to 85°; and the inclined surface has a surface roughness Ra of 1 ?m or less.

Abstract: An article including a glass having that includes SiO2, Al2O3, and B2O3 and least one of Li2O, Na2O, K2O, MgO, CaO, SrO, BaO, SnO2, ZnO, La2O3, F, and Fe2O3, wherein the glass includes a dielectric constant of about 10 or less and/or a loss tangent of about 0.01 or less, both as measured with signals at 10 GHz.

Abstract: Optically transparent glass ceramic materials comprising a glass phase containing and a crystalline tungsten bronze phase comprising nanoparticles and having the formula MxWO3, where M includes at least one H, Li, Na, K, Rb, Cs, Ca, Sr, Ba, Zn, Cu, Ag, Sn, Cd, In, Tl, Pb, Bi, Th, La, Pr, Nd, Sm, Eu, Gd, Dy, Ho, Er, Tm, Yb, Lu, and U, and where 0<x<1. Aluminosilicate and zinc-bismuth-borate glasses comprising at least one of Sm2O3, Pr2O3, and Er2O3 are also provided.

Abstract: Provided is an alkali-free glass substrate having a high strain point and excellent bubble count, and a method for manufacturing the alkali-free glass substrate. The method includes: a batch preparing process of preparing a raw material batch so as to obtain alkali-free glass containing, in mass %, 50 to 80% of SiO2, 15 to 30% of Al2O3, 0 to 4.5% of B2O3, 0 to 10% of MgO, 0 to 15% of CaO, 0 to 10% of SrO, 0 to 15% of BaO, 0 to 5% of ZnO, 0 to 5% of ZrO2, 0 to 5% of TiO2, 0 to 15% of P2O5 and 0 to 0.5% of SnO2 as a glass composition; a melting process of melting the prepared raw material batch; a fining process of fining the molten glass; and a forming process of forming the fined glass into a sheet shape. The raw material batch is melted such that a bubble enlarging temperature of the obtained glass is lower than a maximum temperature of the fining process.

Abstract: Strengthened glass substrates with glass fits and methods for forming the same are disclosed. According to one embodiment, the present invention provides a glass frit with a coefficient of thermal expansion less than or equal to the coefficient of thermal expansion of the glass substrate where it is going to be painted. The glass frit of the present invention has similar ion exchange properties to the glass substrate that is going to be used to paint with the glass frit allowing the glass substrate to be ion-exchanged. The glass frit of the present invention is mixed with an organic carrier.

Abstract: Bulk paint and ceramic powder systems, methods of forming same, and methods of forming a flexible ceramic coating on a metal substrate are disclosed. The systems may include a ceramic composition having between 2 to 30 weight percent of an alkali metal oxide, such as K2O, Na2O, and Li2O or mixtures thereof, between 10 to 74 weight percent SiO2, and between 23 to 79 weight percent B2O3. Additives that are nonwetting with molten metals, such as boron nitride, provide durable coatings for metal processing operations. The ceramic composition may include less than 5 weight percent additional metal oxides. The bulk paint system further may include water and a cellulosic suspension agent to form a bulk paint. The ceramic powder system may be processed to form a uniform powder. The bulk paint or uniform powder may be applied to a metal substrate, such as a ferrous metal substrate, dried, and heated to form a flexible coating on the metal substrate.

Abstract: A method of etching a substrate comprises: contacting a substrate having a thickness with an etchant disposed in a vessel for a period of time until the thickness has reduced by at least 2 ?m and at an average rate of 1 ?m per minute to 6.7 ?m per minute, the etchant having a temperature of 170° C. to 300° C. and comprising a molten mixture of two or more alkali hydroxides; and ceasing contacting the substrate with the etchant. The etchant in some instances comprises a molten mixture of NaOH and KOH. For example, the etchant in some instances includes a molten mixture of 24 wt. % to 72 wt. % NaOH, and 76 wt. % to 28 wt. % KOH. In some instances, the method alters the weight percentage of Na+, K+ and Li+ in the composition of the surface of the substrate by less than 1%.

Abstract: Described herein are articles and methods of making articles, for example glass articles, comprising a thin sheet and a carrier, wherein the thin sheet and carrier are bonded together using a modification (coating) layer, for example a coating layer comprising a cationic surfactant or a coating layer comprising an organic salt, and associated deposition methods. The modification layer bonds the thin sheet and carrier together with sufficient bond strength to prevent delamination of the thin sheet and the carrier during high temperature (? 500° C.) processing while also preventing formation of a permanent bond between the sheets during such processing.

Abstract: The present invention relates to method for producing construction aggregate, comprising the steps of: (i) preparing materials, which comprises (% by weight): fly ash (80 to 99.75%); alkaline activator (0.25 to 20%); water (6 to 30% of total weight of fly ash and alkaline activator); (ii) mixing the alkaline activator with all the aforementioned water amount to create alkaline activator solution, after which will be mixed with fly ash to create geopolymer mortar; (iii) molding the geopolymer mortar with the compressive force of 2 MPa and more with desired dimension, wherein the molding is carried out with hydraulic pressing, extrusion, rolling or tablet lamination. (iv) solidifying; and (v) optionally, crushing the construction aggregate obtained above to a predefined dimension. Besides, the present invention relates to the construction aggregate from fly ash obtained by the above mentioned method.

Abstract: A ceramic powder material containing a garnet-type compound containing Li, wherein the ceramic powder material has a pore volume of 0.4 mL/g or more and 1.0 mL/g or less.

Abstract: A solid composition according to the present disclosure is a solid composition to be used for forming a functional ceramic having a crystal phase, and contains an oxide constituted by a crystal phase different from the crystal phase of the functional ceramic at normal temperature and normal pressure, and an oxoacid compound. The oxoacid compound preferably contains at least one of a nitrate ion and a sulfate ion as an oxoanion. Further, the oxide preferably has a crystal grain size of 10 nm or more and 200 nm or less.

Abstract: Methods, apparatus and systems using heat exchanger reactors to form polymer derived ceramic materials, including methods for making polysilocarb (SiOC) precursors.

Abstract: A cubic boron nitride sintered material includes: more than or equal to 20 volume % and less than 80 volume % of cubic boron nitride grains; and more than 20 volume % and less than or equal to 80 volume % of a binder phase, and when a carbon content is measured from a cubic boron nitride grain into the binder phase in a direction perpendicular to an interface between the cubic boron nitride grain and the binder phase using TEM-EDX, a first region having a carbon content larger than an average value of a carbon content of the binder phase exists, the interface exists in the first region, and a length of the first region is more than or equal to 0.1 nm and less than or equal to 10 nm.

Abstract: A Li3Mg2SbO6-based microwave dielectric ceramic material easy to sinter and with high Q value, and a preparation method thereof are disclosed. A chemical formula of the material is Li3(Mg1-xZnx)2SbO6, wherein 0.02?x?0.08. The preparation method includes: 1) mixing and ball-milling Sb2O3 and Li2CO3 according to a chemical ratio and then drying, and conducting pre-sintering to obtain a Li3SbO4 phase; and 2) mixing and ball-milling MgO, ZnO and Li3SbO4 powder according a chemical ratio of Li3(Mg1-xZnx)2SbO6 and then drying, conducting granulation and sieving after adding an adhesive, pressing into a cylindrical body, and sintering the cylindrical body into ceramic in the air at 1325° C. and under normal pressure, wherein a dielectric constant is 7.2-8.5, a quality factor is 51844-97719 GHz, and a temperature coefficient of resonance frequency is ?14-1 ppm/° C.

Abstract: A method of designing a cement slurry may include: (a) selecting at least a cement and concentration thereof, water and concentration thereof, and, optionally, at least one supplementary cementitious material and a concentration thereof, such that a cement slurry comprising the cement, the water, and, if present, the at least one supplementary cementitious material, meet a density requirement; (b) calculating a thickening time of the cement slurry using a thickening time model; (c) comparing the thickening time of the cement slurry to a thickening time requirement, wherein steps (a)-(c) are repeated if the thickening time of the cement slurry does not meet or exceed the thickening time requirement, wherein the selecting comprises selecting different concentrations and/or different chemical identities for the cement and/or the supplementary cementitious material than previously selected, or step (d) is performed if the thickening time of the cement slurry meets or exceeds the thickening time requirement; and p

Abstract: This method for producing a body obtained by processing a solid carbon-containing material includes: a step of preparing the solid carbon-containing material having at least a surface composed of solid carbon; and a step of processing the solid carbon-containing material. The step of processing the solid carbon-containing material includes: a sub-step of forming non-diamond carbon by heat-treating the solid carbon in the surface of the solid carbon-containing material; and a sub-step of removing at least a part of the non-diamond carbon.

Abstract: A plant treatment composition comprising: an aqueous phase comprising a plant nutrient; and an organic phase comprising a substituted urea or substituted thiourea compound, dissolved in an organic solvent; and an emulsifier; wherein the composition is in the form of an emulsion having droplets of the organic phase dispersed in the aqueous phase.

Abstract: A process for producing coated urea-containing fertilizer particles, comprising the following steps: A) forming at least one polyurea layer on the uncoated urea-containing fertilizer, and then B) forming at least one polyurethane layer on the at least one polyurea layer on the urea-containing fertilizer.

Abstract: Disclosed herein are processes and reaction systems for controlling a temperature of an oligomerization reaction zone using a heat exchange system.

Abstract: This method comprises passing a residual stream into a flash drum to form a gaseous overhead flow and liquid bottom flow, and feeding the bottom flow into a distillation column, It comprises cooling the overhead flow in a heat exchanger to form a cooled overhead flow. It comprises the extraction of a gaseous overhead stream at the head of the distillation column, and the formation of at least one effluent stream from the overhead stream and/or from the top stream. The separation of the cooled overhead flow comprises passing the cooled overhead flow into an absorber, and injecting a methane-rich stream into the absorber to place the cooled overhead flow in contact with the methane-rich stream.

Abstract: An extractive distillation column system contains a combination column and a side rectification column. A process can be used for separation of butenes from C4-hydrocarbon streams using the extractive distillation column system.

Abstract: The present invention pertains to a novel process of manufacturing the compound 2,3,3,3-tetrafluoropropene (1234yf). The compound 1234yf is the newest refrigerant with zero OPD (Ozone Depleting Potential) and zero GWP (Global Warming Potential). Thus, the invention relates to a process, involving a carbene generation route, for the manufacture of the compound 2,3,3,3-tetrafluoropropene (1234yf), of the compound 243db (2,3-dichloro-1,1,1-trifluoropropane), and optionally of the compound 2-chloro-1,1,1-trifluoropropene (1233xf) via carbene route and compound 243db (2,3-dichloro-1,1,1-trifluoropropane). The invention also relates to a process for the manufacture of the compound 2,3,3,3-tetrafluoropropene (1234yf), wherein the compound 243db (2,3-dichloro-1,1,1-trifluoropropane) serves as a starting material, for the manufacture of the compound 2,3,3,3-tetrafluoropropene (1234yf).

Abstract: Proposed is a process for producing methanol from synthesis gas by means of multi-stage, for example two-stage, heterogeneously catalyzed methanol synthesis, wherein the methanol product formed in every synthesis stage is separated by condensation and the remaining residual gas is supplied to the downstream synthesis stage or after separation of a purge stream recycled to the first synthesis stage as a recycle stream. According to the invention after each synthesis stage the residual gas streams have separated from them a respective purge stream, from which, using one or more hydrogen recovery apparatuses, hydrogen is separated and recycled to the first synthesis stage. The ratio of the individual purge streams and their total molar flow may optionally be varied to allow better control of the reaction in the individual synthesis stages and to allow reaction to the advancing deactivation of the catalysts present therein.

Abstract: The present disclosure relates to a method for preparation of 1,4-cyclohexanedimethanol. According to the present disclosure, two step reduction reactions are conducted using terephthalic acid as starting material, and an isomerization process for increasing the rate of trans isomers of CHDA is introduced therebetween, thereby providing a method capable of stably preparing CHDM with high rate of trans isomers.

Abstract: A one pot synthesis of a mixed macrocycle of resorcinol and pyrogallol is disclosed using an acidic catalyst by conventional as well as by microwave assisted methods. Compared with traditional synthesis, the microwave mediated tactic provides a simple, greener route and affords higher compound yields in a shorter period. Moreover, the catalyst can be efficiently reused without any loss in activity.

Abstract: The present invention generally relates to processes for purification, recovery, and conversion of chlorophenol salts (e.g., 2,5-dichlorophenol and salts thereof). In various aspects, the present invention is related to removing one or more impurities from chlorophenol salt-containing process streams and/or recovering chlorophenol salts from process streams for use of the recovered chlorophenol elsewhere in an integrated process. Process streams that may be treated in accordance with the present invention include those incorporating one or more chlorophenol salts in a feed mixture and also those where one or more chlorophenol salts are present in a product or by-product stream of an integrated process. For example, conversion processes of the present invention are suitable as one piece of an integrated process for producing 3,6-dichloro-2-methoxybenzoic acid (dicamba) or a salt or ester thereof or a process for producing 2,4-dichlorophenoxyacetic acid (2,4-D) or a salt or ester thereof.

Abstract: Process for the alkoxycarbonylation of trivinylcyclohexane.

Abstract: Provided is a plasticizer composition including: a cyclohexane-1,2-diester-based substance of the following Chemical Formula 1; and a citrate-based substance of the following Chemical Formula 2: wherein in Chemical Formula 1 and Chemical Formula 2: R1 and R2 each independently are a C8 to C10 alkyl group; and R3 to R5 each independently are a C5 to C10 alkyl group.

Abstract: The present disclosure relates to a process to prepare esters of an amino carboxylic acid of the formula (I) comprising the steps of reacting an aminocarboxylic acid present as a cyclic amide of the formula II and an alkanol of the formula R—(O-A)mOH in the presence of the Brønsted-Lowry acid at a temperature of between 60 and 200 degrees C. wherein the total molar amount of aminocarboxylic acid to the molar amount of the alkanol is between 1:0.8 and 1:1.5 and wherein the Brønsted-Lowry acid is not added to the reaction mixture until least 50% of the total of the alkanol and cyclic amide are added to the reaction mixture.

Abstract: Formulations containing pharmaceutically active compounds with improved stability.

Abstract: The present invention provides a process for preparing 2-methyl-N-(2?-methylbutyl) butanamide of the following formula (1):the process comprising: subjecting an ?-arylethyl-2-methylbutylamine compound of the following general formula (2): wherein Ar represents a substituted or unsubstituted aryl group having 6 to 20 carbon atoms, to N-2-methylbutyrylation to form an N-?-arylethyl-2-methyl-N-(2?-methylbutyl)butanamide compound of the following general formula (3): wherein Ar is as defined above, and removing the ?-arylethyl group of the resulting compound (3) to form 2-methyl-N-(2? -methylbutyl)butanamide (1).

Abstract: The present invention provides for methyl)-4-amino-2R-methyl butanoic acid ethyl ester sodium salt, a novel process for the preparation of crystalline Form B of N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-2R-methyl butanoic acid ethyl ester sodium salt.

Abstract: The present invention relates to novel benzylideneacetone derivatives or uses thereof, more specifically, the present invention relates to a pharmaceutical composition for preventing or treating, or food composition for ameliorating a cancer or a bone disease comprising a compound defined by Formula 1 or pharmaceutically acceptable salt thereof as an active ingredient.

Abstract: In one aspect, the present disclosure provides compounds of the formula (I): wherein the variables are as defined herein. In another aspect, the present disclosure provides compounds of the formula (V): wherein the variables are as defined herein. In another aspect, the present disclosure also provides methods of preparing the compounds disclosed herein. In another aspect, the present disclosure provides antibody drug conjugates comprising compounds of the present disclosure. In another aspect, the present disclosure also provides pharmaceutical compositions and methods of use of the compounds and anti-body drug conjugates disclosed herein.

Abstract: The present invention relates to: novel selenopsammaplin A and a derivative thereof, which have anticancer activity; a preparation method therefor; and a pharmaceutical composition containing the same as active ingredients and, more specifically, to: a novel compound selenopsammaplin A and a derivative thereof which exhibit more excellent anticancer activity since a disulfide moiety thereof is substituted with diselenide according to research on the structural activity of psammaplin A, which is known to have an effect of inhibiting the growth of cancer cells; a preparation method therefor; and a composition for preventing or treating cancer, containing the same as active ingredients. According to the present invention, the novel selenopsammaplin A and the derivative thereof exhibit excellent anticancer activity on various human cancer cell lines so as to be expected to be effectively usable in a pharmaceutical composition for cancer prevention and treatment.

Abstract: Provided herein are formulations, processes, solid forms and methods of use relating to (E)-1-(4-(1-(((4-cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carboxylic acid.

Abstract: The present invention is directed to compounds, compositions and methods for preventing, treating or curing Hepatitis B (HBV) infection in human subjects or other animal hosts. The compounds are as also pharmaceutically acceptable, salts, prodrugs, and other derivatives thereof as pharmaceutical compositions and methods for treatment, prevention or eradication of HBV infection.

Abstract: The present invention relates to compounds of formula (1). The compounds are suitable for use in electronic devices, in particular organic electroluminescent devices, comprising these compounds. In some embodiments, the compounds are used as matrix materials for phosphorescent or fluorescent emitters as well as a hole-blocking or electron-transport materials.

Abstract: Disclosed herein are compounds for activating the Reelin signaling system for the treatment of neurological disorders Further provided are compounds and methods for activating a lipoprotein receptor, such as ApoER2 or VLDLR.

Abstract: Disclosed herein are embodiments of a compound that can be used as a supramolecular sensor for determining the presence of analytes (e.g., illicit drugs), and for identifying and/or quantifying the analytes. Also disclosed herein is a parallel synthesis method for making compound embodiments, as well as method embodiments for using the compound embodiments. Array embodiments comprising one or more compound embodiments disclosed herein also are described.

Abstract: Compounds of the formula (I), wherein the substituents are as defined in claim 1, useful as pesticides, and especially fungicides.

Abstract: The present disclosure relates to novel lymphoid-specific tyrosine phosphatase (LYP, encoded by the PTPN22 gene) inhibitors, and to methods of making and using the novel LYP inhibitors. Thus, the compounds according to the disclosure may be used for treating diseases or disorders associated with PTPN22 genetic polymorphism, including type 1 diabetes, rheumatoid arthritis, systemic lupus erythematosis, Graves' disease, Addison's disease, vitiligo, juvenile arthritis, Hashimoto thyroiditis, and other rarer diseases. Furthermore, these LYP inhibitors may be served for a novel class of cancer immunotherapy. The compounds can be injected or orally administered.

Abstract: The present invention relates to novel fluorophores and their use in combination with novel nucleic acid molecules, called aptamers, that bind specifically to the fluorophore and thereby enhance the fluorescence signal of the fluorophore upon exposure to radiation of suitable wavelength. Molecular complexes formed between the novel fluorophores, novel nucleic acid molecules, and their target molecules are described, and the use of multivalent aptamer constructs as fluorescent sensors for target molecules of interest are also described.

Abstract: The present invention provides methods of inducing proliferation of and/or differentiating cells comprising contacting cells with compounds within the methods of the invention. The present invention further provides cells obtainable by the methods of the invention.

Abstract: Described herein is a perfluorinated aminoolefin compound of general formula (I): CFY?CXN(Rf)CF2Rf? where: (a) Rf and Rf? are (i) independently selected from a linear or branched perfluoroalkyl group having 1-8 carbon atoms, optionally comprising at least one catenated O or N atom, or (ii) bonded together to form a perfluorinated ring structure having 4-8 ring carbon atoms, optionally comprising at least one catenated O atom; and (b) X and Y are (i) independently selected from a perfluoroalkyl group having 1-4 carbon atoms, or (ii) bonded together to form a perfluorinated ring structure having 5-6 ring carbon atoms. Such compounds may be used in heat transfer, foam blowing or immersion cooling applications, or as a working fluid in a Rankine cycle, a coating or lubricant, or as a dielectric fluid. Also disclosed herein is a method for making such compounds.

Abstract: Compounds of Formula 1 and pharmaceutically acceptable compositions thereof are useful as TLR7/8 antagonists.

Abstract: The compounds of Formula Ib, Formula Ia, and Formula I are described herein along with their polymorphs, stereoisomers, tautomers, prodrugs, solvates, and pharmaceutically acceptable salts thereof. The process of preparation of the compounds of Formula Ib, Formula Ia, and Formula I is also described. The compounds described herein, their polymorphs, stereoisomers, tautomers, prodrugs, solvates, and pharmaceutically acceptable salts thereof are 2-(benzyloxy)pyrimidine derivatives that are inhibitors of PD-1/PD-L1 activation.

Abstract: This disclosure is drawn to pyridine derivatives, compositions thereof, and associated methods, useful for inhibition of SARM1 activity and/or for treating or preventing neurological disorders.

Abstract: Disclosed herein are methods and processes of preparing niraparib and pharmaceutically acceptable salts thereof, and intermediates and their salts useful for the synthesis of niraparib.

Abstract: Compounds of the formula (I) wherein the substituents are as defined in claim 1, useful as pesticides, and especially fungicides.