Abstract: The present invention provides a composition and method for preventing the growth of and/or treating cancerous tumors and/or delaying onset of cancer from tumor-initiating cells. The composition includes an effective amount of a compound of Formula (I) or Formula (II): or any pharmaceutically acceptable salt thereof. The composition is administered alone or in combination with one or more chemotherapeutic agents, biological agents and/or anticancer agents. The method may include administering the composition of the present invention with or without the chemotherapeutic, biological, or other cancer treatment agent to a subject in need thereof intravenously, parenterally, nasally, topically or locally, orally, or by liposome, implant or via vessel-targeted nanosuspension delivery.

Abstract: A wellbore system includes a hanger lock energizing ring, a hanger lock ring, and a shoulder ring. The wellbore system further includes a seal energizing ring coupled to the shoulder ring. The wellbore system also includes a seal element being driven into an energized position by the seal energizing ring. The wellbore system further includes a seal lock energizing ring being driven to move via one or more extensions. The wellbore system includes a seal lock ring being supported, at least in part, by the seal energizing ring. Both the hanger lock ring and the seal lock ring are set, substantially simultaneously, responsive to movement of the one or more extensions.

Abstract: According to one embodiment, an I/O command control apparatus receives authorization information. The authorization information indicates whether or not to permit an execution of an I/O command. The apparatus verifies whether the received authorization information is not tampered with, and whether the received authorization information is issued from a known authorization server. In a case where the authorization information is not tampered with, and is issued from the known server, the apparatus verifies whether or not the authorization information permits to execution of the I/O command. The apparatus permits or prohibits the execution of the I/O command or execution of a control command generated from the I/O command, based on the authorization result.

Abstract: Deployment code that identifies a desired deployment of a computer application onto a computing system comprising one or more compute instances is accessed. The computer application includes a plurality of computing components to be deployed on the one or more compute instances in accordance with the deployment code. Contents of the deployment code are input into a machine learning model (MLM) that has been trained using: a plurality of previously generated deployment codes that identified corresponding desired deployments of corresponding computer applications, and information that identifies successes or failures associated with attempted deployments of the previously generated deployment codes. An output is received from the MLM. Based on the output from the MLM, information indicative of a likelihood of success of deploying the deployment code is sent to a destination.

Abstract: A hand tool includes a handle, at least one driving head, at least one groove and at least one abutting element. The at least one driving head is connected with at least one end of the handle. The at least one groove is disposed on an inner edge of the at least one driving head, and includes an inner wall and at least one margin structure. The at least one margin structure extends from an end of the inner wall, and an angle is between the at least one margin structure and the inner wall. The at least one abutting element is disposed on the at least one groove.

Abstract: A charging system for autonomous charging of an electric vehicle with electric energy includes a vertical charging arm part, a charging cable or busbar connectible to the electric vehicle, and an elongate horizontal charging arm part extendible from the vertical charging arm part toward the electric vehicle. The horizontal charging arm part has a first drive system with a first linear operative direction corresponding to a longitudinal direction of the horizontal charging arm part, allowing a vehicle-side end of the horizontal charging arm part to move autonomously using the first drive system, relative to the electric vehicle relative to a first linear degree of freedom. A second drive system has a second linear operative direction moving the horizontal charging arm part autonomously relative to the electric vehicle relative to a second linear degree of freedom. A method for charging an electric vehicle using the charging system is also provided.

Abstract: A battery-powered electronic resistance welding machine for sheet metal repair, comprising a machine unit (10), which includes a handle (12) and an activation and deactivation button (13), at least one first rod (14), which is constrained in a sliding fashion (F) to a terminal (15) of the machine unit (10), which has, at one free end, a ground electrode or tip (16) that comes into contact with at least one metal portion to create an electrical resistance circuit, at least one second rod (17), constrained in a sliding fashion (F) to the terminal (15), which has, at one free end, a welding or terminal electrode or tip (18) for the fixing of repair accessories of the metal portion. There is a rechargeable battery (11) in the machine unit (10), for example a lithium-polymer accumulator, which allows the electronic resistance welding machine to be powered without using the mains power supply.

Abstract: A carriage rocking system is provided, which is engageable to a front wheel of a carriage to impart a rocking motion thereto during travel. A wheel having a sliding hub is engaged with an axle of the front wheel of the carriage. Translation of a hub assembly to differing positions on a support member of the wheel imparts more or less rocking motion to the carriage.

Abstract: A system for wireless power transfer includes a wireless transmission system and a wireless receiver system. The wireless transmission system is operatively associated with a mouse pad includes a transmission antenna configured to transmit one or both of wireless power signals and wireless data signals within a large charge area, the large charge area having a length of in a range of 50 millimeters (mm) to 300 mm and a width in a range of 150 to 500 mm. The wireless receiver system is configured to power a load of a computer mouse and includes a receiver antenna, the receiver antenna including a plurality of receiver coils, each of the plurality of receiver coils configured to receive one or both of the wireless power signals and the wireless data signals within the large charge area.

Abstract: An underwater acoustic receiver apparatus (100) comprises an acoustic reflector (102, 104, 106, 108) and an acoustic device (110, 114, 116, 118) aimed at the acoustic reflector (102, 104, 106, 108). The acoustic reflector (102, 104, 106, 108) is disposed at a predetermined distance and orientation relative to the acoustic device (110, 114, 116, 118).

Abstract: Embodiments of the present disclosure provide a video playback control method and apparatus, an electronic device and a storage medium. The method includes: receiving a first video playback instruction, where the first video playback instruction is triggered to be generated when a user clicks a video playback control within a first target display area in a music list display interface; and playing a first target video in the first target display area and expanding a height of the first target display area to a set height value, where the first target video takes a first target music, corresponding to the first target music item displayed in the first target display area, as background music. By adopting the above technical solution, the embodiment of the present disclosure may realize a function of playing, through the music list, a video whose background music is the music in the music list.

Abstract: The present disclosure relates to antibody-drug conjugates comprising ALK5 inhibitors and their uses.

Abstract: Many strains of the human pathogen Neisseria meningitidis carry a compact Cas9 (NmeCas9) that can serve to limit genetic exchange via natural transformation. Cas9 orthologues (including NmeCas9) have recently been adopted for RNA-guided genome engineering and DNA binding, adding to the need to define better their activities and properties. The present invention examines DNA cleavage activities and substrate requirements of NmeCas9, including a set of unusually complex PAM recognition patterns. Unexpectedly, NmeCas9 is found able to cleave single-stranded DNA (ssDNA) targets in a manner that is RNA-guided but both PAM- and tracrRNA-independent. Beyond the requirement for guide-target pairing, this activity has no apparent sequence requirements, and the cleavage sites are measured from the 5? end of the DNA substrate's RNA-paired region.

Abstract: An electronic parachute deployment system includes an electronic actuator, a control module, a deployment actuator, and a release mechanism. A parachute is positioned on a payload device, such as a racecar, to slow or stop the payload upon receipt of an electronic deployment activation signal. The electronic deployment signal is verified, including determining proper voltage and source. The deployment system includes multiple redundancies including mechanical deployment redundancy, remote deployment redundancy, and power supply redundancy. The control module responsible for monitoring deployment includes indicators and sensors to indicate a status, operation, or mode relative to the operability of the payload device, relative to components of the release mechanism, and relative to the parachute deployment.

Abstract: Devices, networking devices, and switches, among other things, are disclosed. An illustrative switch is disclosed to include a plurality of optical Input/Output (I/O) ports; a multi-chip module (MCM) assembly including switching circuitry and at least one chiplet that is optically coupled with one of the plurality of optical I/O ports; and a controller coupled with the at least one chiplet and configured to couple the at least one chiplet with a Quantum Key Distribution (QKD) device.

Abstract: A control device consists of a handle with buttons and an on/off trigger, a sphere, an optical, electromagnetic or laser sensor, a fixed base with a half-sphere, and a part situated below said base. The device is designed to simulate a response from working mechanisms and can be used for controlling different manned and unmanned devices, air, land and underwater devices, as well as for working with computer equipment and also for controlling spacecraft.

Abstract: A device for adjusting a sprocket of a chain drive includes a bearing journal having a free end and a fixed end, a rotary bearing arranged on the bearing journal, and a sprocket guided on the rotary bearing. A stop is formed on the bearing journal and at least one spring element is arranged between the rotary bearing and the stop, wherein a preloading means is provided via a clamp which preloads the rotary bearing against the spring element.

Abstract: In certain aspects, a memory device includes a vertical transistor including a semiconductor body extending in a first direction, a stack structure including interleaved dielectric layers and conductive layers each extending perpendicularly to the first direction, an electrode layer including a conductive material and coupled to a first end of the semiconductor body, and a storage layer over the electrode layer. The electrode layer and the storage layer extend in the first direction through the stack structure.

Abstract: A facial authentication apparatus comprises: a camera arranged at a position capable of facing an authentication object person and captures a face image of the authentication object person; a display arranged below the camera and displays the face image captured by the camera; a card reader arranged below the display and on a front side as seen from the authentication object person, and reads a card presented by the authentication object person; and a wall member(s) arranged so as to extend to at least a front end portion of the card reader from an upper end portion of the display.

Abstract: Some embodiments include apparatuses and methods of forming the apparatuses. One of the apparatuses includes a memory cell including a first transistor, a second transistor, and a dielectric structure formed in a trench. The first transistor includes a first channel region, and a charge storage structure separated from the first channel region. The second transistor includes a second channel region formed over the charge storage structure. The dielectric structure includes a first dielectric portion formed on a first sidewall of the trench, and a second dielectric portion formed on a second sidewall of the trench. The charge storage structure is between and adjacent the first and second dielectric portions.

Abstract: A filtering device is configured to estimate the characteristics of noise superposed on measurement data relating to the status of a controlled machine based on the status information representing the status of a controlled machine, thus adjusting the filtering to eliminate noise based on the estimated noise characteristics.

Abstract: A multiple well device for processing fluid samples is provided, comprising a plate including a plurality of wells, each well including a first sub-well and a second sub-well, separated by an individual dialysis membrane; each individual dialysis membrane having a top end and a bottom end, having a continuous taper from the top end to the bottom end, each first sub-well and each second sub-well having an upper end and a lower end, and side walls, wherein one side wall is a common side wall shared by the first sub-well and the second sub-well, the common side wall having a continuous tapered cut-out with the individual dialysis membrane fluid-tightly sealed in the continuous tapered cut-out.

Abstract: The present invention is to provide a photoelectric conversion element with an excellent sensitivity, an imaging element, an optical sensor, and a compound. The photoelectric conversion element of the present invention includes, in the following order, a conductive film, a photoelectric conversion film, and a transparent conductive film in which the photoelectric conversion film contains a compound represented by Formula (1) and a coloring agent.

Abstract: Disclosed is a fruit picking method based on a visual servo control robot, comprising: placing a throwing apparatus and a fixed photosensitive device at a first position to obtain a fixed photosensitive image; generating a first throwing path, a second throwing path, and a third throwing path; arranging recovery apparatuses; performing simultaneous rotational throwing processing to throw a first wireless photosensitive device, a second wireless photosensitive device, and a third wireless photosensitive device; receiving a first photosensitive image sequence and a second photosensitive image sequence of the first wireless photosensitive device and the second wireless photosensitive device; receiving a third photosensitive image sequence of the third wireless photosensitive device; generating a spatial position of a fruit on a to-be-picked fruit tree; and performing fruit picking processing using the visual servo control robot according to the spatial position of the fruit.

Abstract: An orbital scroll wrap and a fixed scroll wrap of a scroll compressor include respective scroll start portions each having a bulbous shape defined by connecting an involute start point of an outer-surface involute curve and an involute start point of an inner-surface involute curve to each other with a plurality of arcs. At least one of the scroll start portions has a tiered shape wherein an n number (where n?2) of tiers each having the bulbous shape are stacked in an axial direction of a main shaft. Letting involute-start-point angles of the outer-surface involute curves in respective tiers of the scroll start portion having the tiered shape be ?os(1), ?os(2), ?os(3), . . . , and ?os(n) in order from tip to base of the scroll start portion, the following is satisfied: ?os(1)>?os(2)>?os(3)> . . . >?os(n); and 0.3?<?os(1)-?os(n)<0.7?.

Abstract: The present disclosure relates to use of an aspirin compound in facilitating exogenous nucleic acid delivery and/or expression.

Abstract: There is provided a nozzle of a cleaner device that cleans an object to be cleaned having a convex surface. The nozzle comprises: a spray orifice that is positioned outside the convex surface and from which a fan-shaped layer of a cleaning fluid is sprayed onto the convex surface. The spray orifice is shaped such that the sprayed fan-shaped layer of the cleaning fluid is convexly curved toward the same direction as the convex surface.

Abstract: Provided is an adhesive application system configured to apply a necessary and sufficient amount of an adhesive to a thin steel strip without causing an increase in the equipment cost. The adhesive application system comprises an adhesive application device having adhesive dispensing nozzles (26, 27) for dispensing an adhesive to an adhesive application surface of a thin steel strip; a mechanism configured to elevate and lower the adhesive application device; and adhesive supply ports (17, 18) for supplying the adhesive at a predetermined pressure to the adhesive application device, wherein the adhesive application device has an end face that is to be brought into abutment against the thin steel strip, and wherein outlets of the adhesive dispensing nozzles (26, 27) are spaced inwardly away from the end face of the adhesive application device so that the outlets of the adhesive dispensing nozzles (26, 27) are maintained at a predetermined distance from a lower surface of the thin steel strip.

Abstract: The present invention relates to a novel liquid-liquid extraction process of a bio-oil obtained by an improved thermochemical process. This extraction process gives rise to two distinct phases: an organic phase, with bio-oil of energetic added value, and an aqueous phase, where the following can be obtained by chemical compounds with added value: lactic acid, formic acid, hydroxymethylfurfural, furfural, levulinic acid, monosaccharides, disaccharides and compounds with antioxidant properties, among others.

Abstract: A non-pizzeria vending outlet includes a freezer, a microwave oven, and a cooktop, where the vending outlet has no means for preparing pizza dough or for baking pizza and where the vending outlet overcomes obstacles that deter non-pizzeria restaurants from vending pizza.

Abstract: A personal digital assistant for supporting inspection of at least one device disposed in an inspection target area includes: an abnormality acquisition unit configured to acquire information about an abnormality in the at least one device; a guidance information storage unit configured to store guidance information which at least includes at least one response procedure for each abnormal event in the at least one device and information about response capability required to execute the at least one response procedure; and a display unit configured to refer to the guidance information stored in the guidance information storage unit, and display the guidance information for responding to an abnormal device which is the device where the abnormality is acquired by the abnormality acquisition unit.

Abstract: A system, device, and wireless computer technology-implemented method for providing hearing healthcare education and communication for a patient, his/her communication partner, and a hearing care provider. The system provides the patient at least one educational and experiential module and a method for assessing the patient's comprehension of the module's lessons. The system further provides the patient with a method to select personal hearing aid and communication goals; a method to evaluate his/her progress on achieving each personal goal; and a method to report his/her hearing experiences. The system further provides a method to compare data reported by the patient to personalized thresholds. When one or more of the patient's reports do not meet the thresholds, the system sends automated alerts to the hearing care provider to encourage prompt remedial action and sends automated reminders to the patient to improve the patient's ability to achieve his/her personal goals.

Abstract: An organic light emitting diode and an organic light emitting device including the organic light emitting diode are discussed. The organic light emitting diode can include a first compound represented by the following formula, a second compound as a p-type host, and a third compound as an n-type host in an emitting material layer. As a result, the organic light emitting diode and the organic light emitting device have advantages in the driving voltage, the luminous efficiency and the lifespan.

Abstract: A display assembly for an electronic device can include a printed circuit board, a display panel, and a support structure affixed to the display panel and disposed between the display panel and the printed circuit board.

Abstract: In an embodiment, two or more storage systems are requested to prepare respective local checkpoints for a dataset, wherein each of the two or more storage systems stores portion of the dataset. The two or more storage systems are determined to have established the checkpoint. In response to determining that the local checkpoints have been established, a coordinated checkpoint is completed.

Abstract: A detection method (100) of a lidar (200), the lidar (200), and a system for a vehicle (300) including the same. The lidar (200) is capable of rotating around a rotating shaft, and includes an emitting unit (210) having a plurality of laser emitters (211). The detection method (100) includes: step S101, controlling the plurality of laser emitters (211) to emit laser beams for detection so that the lidar (200) has a non-uniform angular resolution along a horizontal direction; step S102, receiving echoes of the emitted laser beams for detection reflected by a target object and converting the echoes into electrical signals; and step S103, calculating a distance and/or reflectivity of the target object according to the electrical signals. Thereby, an angular resolution along a horizontal direction of the lidar (200) is flexibly configured, flight time and power consumption are reduced, and a detection range of the lidar (200) is improved.

Abstract: A fluid signal generator configured to produce fluid pulses in a fluid column of a wellbore are described. The fluid pulses represent data and/or other information to be transmitted from a downhole device, such as a fluid plug apparatus located within the borehole of the wellbore, to one or more other devices located away from the downhole device, including devices located above a surface of the wellbore. The fluid plug may be configured to provide a fluid seal between a first portion of the wellbore and a second portion of the wellbore prior to and during a fluid treatment procedure being performed on the wellbore.

Abstract: Systems and methods relating to dynamic spargers for generating fine bubbles within reactors such as biological and chemical reactors. A sparger system is positioned within a reactor and comprises a support plate, multiple annular shrouds engaged with the support plate, and spargers positioned within the annular shrouds defining a gap between an interior surface of the annular shroud and an exterior surface of the corresponding sparger. Liquid flows through the defined gap between an interior surface of the annular shroud and an exterior surface of the sparger. Acceleration of the liquid through the gap shears bubbles at the exterior surface of the sparger creating bubbles or fine bubbles.

Abstract: The invention is directed to an electronic device. The electronic device provides, for display on a display device, a user interface including a first set of columns, two or more columns in the first set of columns each including two or more menu items. The electronic device receives a selection input. In response to receiving the selection input, in accordance with a determination that the selection input corresponds to selection of a first column the electronic device provides, for display on the display device, a second set of columns, two or more of the columns in the second set of columns corresponding to different subsets of menu items that were displayed in the first column that was selected in response to the selection input.

Abstract: A purified composition of steviol glycoside molecules is described. The composition imparts desirable taste, flavor and flavor modifying properties to food, beverages, and other consumable products.

Abstract: The present invention provides a hot stamping component which includes a base steel sheet including carbon (C) in an amount of 0.28 wt % to 0.50 wt %, silicon (Si) in an amount of 0.15 wt % to 0.7 wt %, manganese (Mn) in an amount of 0.5 wt % to 2.0 wt %, phosphorus (P) in an amount of 0.03 wt % or less, sulfur (S) in an amount of 0.01 wt % or less, chromium (Cr) in an amount of 0.1 wt % to 0.6 wt %, boron (B) in an amount of 0.001 wt % to 0.005 wt %, at least one of titanium (Ti), niobium (Nb), and molybdenum (Mo), and a balance of iron (Fe) and other unavoidable impurities, wherein a content of titanium (Ti), niobium (Nb) and molybdenum (Mo) satisfies the following equation. 0.015?0.33(Ti+Nb+0.33(Mo))?0.

Abstract: A semiconductor device in which variations in characteristics, deterioration of elements, and abnormality in shape are inhibited is provided. The semiconductor device includes a first region including a plurality of elements and a second region including a plurality of dummy elements. The second region is provided in an outer edge of the first region, and the element and the dummy element each include an oxide semiconductor. The element and the dummy element have the same structure, and a structure body included in the element and a structure body included in the dummy element are formed with the same material and provided in the same layer. The oxide semiconductor includes In, an element M (M is Al, Ga, Y, or Sn), and Zn.

Abstract: he invention discloses a porphyrin-based metal coordination conjugated polymer, a preparation method therefor, and an application thereof in photocatalytic degradation of organic pollutants. The catalyst of the present invention has an 18?-conjugated skeleton, a nearly planar macrocyclic molecule, a stable rigid structure and a very stable highly conjugated system, so that the catalyst has excellent photoelectric conversion efficiency, a wide range of absorption spectra, strong redox capacity, and good chemical and thermal stability. A metal coordinated porphyrin acts as active center, a large number of derivatives can be derived, and the method has emerged as a promising alternative for the photocatalytic degradation of environmental pollutants and the like.

Abstract: This disclosure relates to an implantable electric circuit (300) for medical stimulation The circuit comprises a plurality of capacitors (301) and a network of resistors (302). Each of the plurality of capacitors (301) is configured to couple radio frequency energy from one of a plurality of electrically conductive filaments (5) of a lead to the network of resistors (302). Further, the network of resistors (302) is configured to connect the plurality of capacitors (301) together to dissipate the radio frequency energy between the plurality of electrically conductive filaments. The network of resistors dissipates the energy between the filaments, which reduces negative impacts for the patient when subjected to MRI imaging. Further, no ground is required and as a result, the circuit can be placed into a header of an implantable pulse generator or into the lead itself.

Abstract: An inflatable product is provided including a top sheet, a bottom sheet, a lateral confining sheet, and an internal connecting sheet. A peripheral edge of the top sheet is connected to an upper edge of the lateral confining sheet, and a peripheral edge of the bottom sheet is connected to a lower edge of the lateral confining sheet, forming an inflatable chamber. An upper edge of the internal connecting sheet is connected to the top sheet, a lower edge of the internal connecting sheet is connected to the bottom sheet, and a connecting part of the internal connecting sheet, located between the upper edge and the lower edge of the internal connecting sheet, is connected to the lateral confining sheet along at least one welding seam. The at least one welding seam may form at least one embossment on an outside of the inflatable product.

Abstract: Disclosed herein are engineered oligonucleotides for selective inhibition of polypeptide expression and activity. Also disclosed herein are methods of selectively inhibiting polypeptide expression and activity contacting an engineered oligonucleotide with a polynucleotide encoding the polypeptide.

Abstract: A fully connected ring oscillator circuit includes a plurality of first ring oscillator loops, a plurality of second ring oscillator loops, a plurality of ring oscillators and a plurality of coupled ring oscillators. Each first ring oscillator loop extends along a first axis. Each second ring oscillator loop extends along a second axis that is transverse to the first axis and intersects each of the first ring oscillator loops. Each ring oscillator includes one of the first ring oscillator loops connected to one of the second ring oscillator loops. Each coupled ring oscillator includes two of the ring oscillators that are connected to each other through a programmable weighted coupling block.

Abstract: The present disclosure relates to an antibody that binds to the CD38 protein or an antigen-binding portion thereof, a preparation method therefor and the use thereof. The antibody can bind to human CD38 with high affinity, has an inhibitory effect on the CD38 enzyme, has a CDC, ADCC, and/or ADCP killing activity with regard to different tumor cells, and has an anti-tumor function. Moreover, the antibody does not cause red blood cell lysis.

Abstract: Structure and functionality reduce differential leakage current and compensate for differential capacitance discharge current from diode configurations to mitigate differential output polarity reversal that may occur in driver circuits. In an example driver circuit, one of two current sources coupled between a supply voltage and one output node is disabled during a driver disable time period (tpz) while the other continues to operate during a pre-charge monopulse time period (td) within tpz. A third current source on the other side of the driver circuit and coupled to ground is also disabled during tpz. During td, the following components are enabled: a charge current source coupled between the supply voltage and a second output node; a pair of current switches respectively coupled to the output nodes; and a pair of pull-down switches respectively coupled to control terminals of the current switches.

Abstract: A particle suction nozzle including a body that has a suction mouth as well as at least a portion of a fastening system designed to link the nozzle to a support. The fastening system has at least one tubular insert made of elastically deformable material rigidly connected to the body and designed to be fitted onto a linking element rigidly connected to the support, and once fitted, to be immobilized in relation to the linking element and at a distance from the support. A suction device includes the suction nozzle.