Patents Issued in May 9, 2023
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Patent number: 11644390Abstract: Systems and methods are disclosed herein for contextual data analysis and proactive intervention in industrial plant processes. Each of multiple data streams in an industrial plant are mapped to a common hierarchical data structure, wherein the data streams correspond to respective values or states associated with unit operations, assets, and process streams in the plant. The mapped data streams define hierarchical process relationships between subsets of the unit operations, assets, and process streams. Real-time data is collected to populate at least one level of the hierarchical data structure for certain data streams, wherein future outcomes are predicted for downstream operations based on the collected real-time data for at least one data stream, and at least one other data stream having a defined hierarchical process relationship therewith.Type: GrantFiled: April 28, 2021Date of Patent: May 9, 2023Assignee: Buckman Laboratories International, Inc.Inventors: Narasimha M. Rao, Arun Kumar Raju Ganesan, John Carter
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Patent number: 11644391Abstract: The present invention discloses a fault diagnosis method under a convergence trend of a center frequency, including: (1) acquiring a dynamic signal x(t) of a rotary machine equipment; (2) setting initial decomposition parameters of a variational model; (3) decomposing the dynamic signal x(t) by using the variational model with the set initial decomposition parameters, and traversing a signal analysis band and performing iterative decomposition on the dynamic signal x(t) under the guidance of a convergence trend of a center frequency, to obtain optimized modals {m1 . . . mn . . . mN} and corresponding center frequencies {?1 . . . ?n . . . ?N}; (4) searching a fault related modal mI, guiding parameter optimization by using a center frequency ?I of the fault related modal mI, and retrieving an optimal target component mI including fault information; and (5) performing envelopment analysis on the optimal target component mI, and diagnosing the rotary machine equipment according to an envelope spectrum.Type: GrantFiled: July 30, 2020Date of Patent: May 9, 2023Assignee: SOOCHOW UNIVERSITYInventors: Xingxing Jiang, Changqing Shen, Jianqin Zhou, Dongmiao Song, Wenjun Guo, Guifu Du, Jun Wang, Juanjuan Shi, Weiguo Huang, Zhongkui Zhu
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Patent number: 11644392Abstract: The invention relates to an arrangement having a specimen plate (1) for freezing on a sample for processing in a microtome, which has an upper side (4) for freezing on the sample and a lower side (5), and having a transparent marking frame (6), having opaque regions forming a marking, which is arranged on the specimen plate (1); and to a method for assigning a sample after freezing onto that specimen plate; and to a method for identifying a sample that is frozen onto that specimen plate (1), the marking frame being arranged on the lower side (5) of the specimen plate (1) or so as to fit around the specimen plate (1).Type: GrantFiled: July 16, 2020Date of Patent: May 9, 2023Assignee: Leica Biosystems Nussloch GmbHInventor: Krishna Kishore Nedunuri
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Patent number: 11644393Abstract: The present disclosure provides a low-energy-consumption in-situ extraction system for lunar rare gas and an extraction method. The system includes a screening device, a grinding device and a heating device. The method includes: a. using a robot arm to collect lunar soil and put into the screening device, and screening lunar soil with a particle size below 100 ?m; b. adding and grinding screened lunar soil in the grinding device; c. adding and heating ground lunar soil in the heating device to 150-250° C., and releasing rare gases adsorbed. The present disclosure uses screening, grinding combined with traditional heating methods to achieve low power consumption in extracting rare gases on the surface of the moon, and extraction power consumption is only 10-30% of the power consumption of hot-melt extraction at 900° C. in the prior art, which is beneficial to promote the lunar resource utilization.Type: GrantFiled: November 25, 2020Date of Patent: May 9, 2023Assignees: Institute Of Geology and Geophysics, Chinese Academy of Sciences, Institute of Atmospheric Physics, Chinese Academy of SciencesInventors: Fei Su, Huaiyu He, Ranran Liu, Ziheng Liu, Jiannan Li
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Patent number: 11644394Abstract: A device and method for preparing a solidified cohesionless soil specimen for triaxial test. The device includes a first vessel for storing a grout, a first peristaltic pump, a grouting pipe, a first electrode rod, a direct-current power supply, a first glass stopper, a PMMA pipe, a circumferential grouting cylinder, a first hoop sleevedly provided on the circumferential grouting cylinder, a second hoop sleevedly provided on the PMMA pipe, a return pipe, a second glass stopper, a second electrode rod, a liquid outlet pipe, a first water-stop clamp, a second water-stop clamp, a second vessel for collecting an exudate, and a second peristaltic pump.Type: GrantFiled: December 10, 2021Date of Patent: May 9, 2023Assignee: ZHEJIANG UNIVERSITY OF SCIENCE AND TECHNOLOGYInventors: Jianfeng Zhu, Hao Yang
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Patent number: 11644395Abstract: A method including: providing a sample with M components to be labeled, where M>2; labeling the components with N stains, where N<M so that at least two components are labeled with a common stain; obtaining a set of spectral images of the sample; classifying different parts of the sample into respective classes that distinguish the commonly stained components based on the set of spectral images; and determining relative amounts of multiple ones of the M components in different regions of the sample. Related apparatus are also disclosed.Type: GrantFiled: October 22, 2018Date of Patent: May 9, 2023Assignee: Cambridge Research & Instrumentation, Inc.Inventor: Clifford C. Hoyt
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Patent number: 11644396Abstract: There are disclosed a measuring apparatus and method for measuring the pull-off force of a frangible arrangement connecting a capsule with a tamper evident band of closed annular shape, with an annular ridge that axially retains the tamper evident band, a pusher device that pushes the capsule so as to cause the breakage of the frangible arrangement, a sensor arrangement to detect the tensile force applied by the pusher device, and a lifting and abutting device arranged for supply the capsule to the annular ridge. There are further disclosed a band disengagement arrangement for disengaging the tamper evident band from the annular ridge after the breakage of the frangible arrangement, yet maintaining intact the closed annular shape of the tamper evident band.Type: GrantFiled: March 29, 2021Date of Patent: May 9, 2023Inventor: Danilo Albonetti
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Patent number: 11644397Abstract: This invention relates to a method of evaluating a squeegeeing property of powder for lamination shaping by stable criteria. In this method, the squeegeeing property is evaluated using at least a satellite adhesion ratio of the powder and an apparent density of the powder. The satellite adhesion ratio is the ratio of the number of particles on which satellites are adhered to the number of all particles. If the satellite adhesion ratio is equal to or less than 50%, and the apparent density is equal to or more than 3.5 g/cm3, the squeegeeing property is evaluated as that the powder can be spread into a uniform powder layer in the lamination shaping. Furthermore, if the 50% particle size of a powder obtained by a laser diffraction method is 3 to 250 ?m, the squeegeeing property is evaluated as that the powder can be spread into a uniform powder layer in the lamination shaping.Type: GrantFiled: August 25, 2017Date of Patent: May 9, 2023Assignees: FUKUDA METAL FOIL & POWDER CO., LTD., TECHNOLOGY RESEARCH ASSOCIATION FOR FUTURE ADDITIVE MANUFACTURINGInventors: Seiichi Matsumoto, Yuji Sugitani, Motonori Nishida
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Patent number: 11644398Abstract: An apparatus and a method for testing combined dynamic-static loading strength of a rock-like material are provided. The apparatus and the method can test the combined dynamic-static loading strength of the rock-like material. The apparatus comprises an explosion load loading device, a static load loading device, and a stress wave rod transferring device. The explosion load loading device is connected with one end of the stress wave rod transferring device. The stress wave rod transferring device is connected with a rock-like material specimen. The stress wave rod transferring device is connected with the static load loading device.Type: GrantFiled: October 21, 2022Date of Patent: May 9, 2023Assignee: CHINA UNIVERSITY OF MINING AND TECHNOLOGYInventors: Lixiang Xie, Jiawan Jin, Chao Chen
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Patent number: 11644399Abstract: A thermal analysis apparatus includes: a cylindrical heating furnace extending in an axial direction; a weight detector arranged on a rear-end side in the axial direction of the cylindrical heating furnace and including levers extending in the axial direction to detect a weight; a connecting portion for connecting the cylindrical heating furnace and the weight detector to communicate an internal space of the cylindrical heating furnace with an internal space of the weight detector and positioning the levers from the weight detector into the cylindrical heating furnace; sample holding portions connected to tip ends of the levers and arranged inside the cylindrical heating furnace and holding a sample; resistance heaters arranged to cover the weight detector and energized by an electric current of 6 A or less; and a heater control part for controlling an energization state of the resistance heaters to maintain the weight detector at a constant temperature.Type: GrantFiled: March 6, 2020Date of Patent: May 9, 2023Assignee: HITACHI HIGH-TECH SCIENCE CORPORATIONInventors: Takashi Kumazaki, Kentaro Yamada
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Patent number: 11644400Abstract: An air pressure-machine vision based system for measuring a rheological property of a viscoelastic material includes a machine body, a lifting experiment table system, an air pressure generation control system, an image collection system, and a controlling and information processing system, where the lifting experiment table system, the air pressure generation control system, the image collection system and the controlling and information processing system are mounted on the machine body; the lifting experiment table system includes a lifting table stepping motor, an L-shaped lifting table and a lifting table motor driver, and the lifting table motor driver is connected to the lifting table stepping motor and configured to drive the lifting table stepping motor; and the lifting table stepping motor is connected to the L-shaped lifting table and configured to control lifting of the L-shaped lifting table.Type: GrantFiled: September 2, 2022Date of Patent: May 9, 2023Assignee: China Agricultural UniversityInventors: Xiuying Tang, Xiuzhi Luo, Qinming Sun, Ke He
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Patent number: 11644401Abstract: An apparatus is for use in viscoelastic analysis, for example in coagulation testing of sample liquids, such as blood and/or its elements. In the apparatus for use in viscoelastic analysis, the rotating means are provided below the cup, pin and cup receiving element. A capacitive detection means and temperature control devices may be used in the apparatus for use in viscoelastic analysis. A method of performing viscoelastic analysis, e.g. coagulation analysis, on a sample may use the devices and apparatuses.Type: GrantFiled: January 26, 2017Date of Patent: May 9, 2023Inventor: Harald Leyser
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Patent number: 11644402Abstract: The present invention discloses a simulation device for a preferential flow of a fissured-porous dual-permeability media and an experimental method, and belongs to the technical field of geological engineering. The simulation device comprises a support. The support is detachably connected with a transparent container. The interior of the transparent container is filled with a fissured-porous dual-permeability media experimental model. The top of the transparent container is open. A spraying device is arranged above the transparent container. Liquid rapid outflow ports are formed in the bottom of the transparent container and are connected with a liquid collection device. The present invention further discloses an experimental method of the simulation device and a manufacturing method of the fissured-porous dual-permeability media experimental model. The simulation device of the present invention can highlight and enhance the preferential flow experiment effect.Type: GrantFiled: May 20, 2020Date of Patent: May 9, 2023Assignee: Guilin University of TechnologyInventors: Bin Zhu, Jilin Chen, Mingqing Zhu, Jing Zhang, Caimei Luo, Jiahui Wu
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Patent number: 11644403Abstract: A method for analyzing an interaction between a sample surface and a drop of liquid comprises applying the drop of liquid to the sample surface and illuminating the drop of liquid using at least two light sources. The at least two light sources are each arranged at a light source position surrounding the drop of liquid. Light reflected from the drop of liquid detecting and a sensor position on a sensor of a camera is determined for each detected light reflection. Light source positions are assigned to individual light source positions. A position of the drop of liquid is calculated relative to the sensor and an item of size information of the drop of liquid is determined. The position and the item of size information are calculated from the pairs of one sensor position and one associated light source position.Type: GrantFiled: May 14, 2021Date of Patent: May 9, 2023Assignee: Kruss GmbH, Wissenschaftliche LaborgerateInventors: Tim Kristjan Stüven, Bernd Friedrich, Alexander Buchholz, Marlitt Jönsson, Florian Weser
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Patent number: 11644404Abstract: An improved method of characterizing the PSD of particles.Type: GrantFiled: October 9, 2018Date of Patent: May 9, 2023Assignee: Univation Technologies, LLCInventor: Zhenshuo Bobby Liu
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Patent number: 11644405Abstract: The present disclosure relates to a dissociation reagent for tumor tissues. The dissociation reagent does not contain collagenase or trypsin but further contains hyaluronidase or a mixture of hyaluronidase and DNase I. The present disclosure also relates to use of the dissociation reagent in dispersing tumor tissues and detecting expression level of molecular markers on cell surface by flow cytometry. The dissociation reagent of the present disclosure does not cause degradation of molecular markers on cell surface such as CD8, PD-1, Tim-3, Lag-3 and the like, thus does not affect downstream assays.Type: GrantFiled: September 13, 2019Date of Patent: May 9, 2023Assignee: WuXi AppTec (Suzhou) Co. Ltd.Inventors: Ning Zhang, Qiyao Zhang, Yan Liu, Qunsheng Ji
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Patent number: 11644406Abstract: An apparatus for evaluating focus, including (a) a stage configured to hold a specimen; and (b) an optical train including a radiation source, calibration optic, objective and detector, the optical train forming a first path wherein radiation from the radiation source is directed to the calibration optic and then a first portion of the radiation is directed to the detector, thereby forming a first image on the detector, wherein a second portion of the radiation follows a second path from the calibration optic then through the objective to the specimen, wherein the optical train forms a third path wherein radiation reflected from the specimen is transmitted through the objective, then to the detector, thereby forming a second image on the detector, and wherein the radiation that forms the first image is astigmatic.Type: GrantFiled: June 11, 2020Date of Patent: May 9, 2023Assignee: PACIFIC BIOSCIENCES OF CALIFORNIA, INC.Inventors: Yoshinao Taketomi, Dale Buermann, Maxim Abashin, Donald V. Rosenberry
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Patent number: 11644407Abstract: A cell sorting system that automatically generates a sorting strategy based on examples of target events provided by an operator. The target events can be selected using measurements ranging from traditional flow cytometry measurements to derived measurements that are computationally expensive to complex measurements such as images.Type: GrantFiled: December 8, 2021Date of Patent: May 9, 2023Assignee: BECTON, DICKINSON AND COMPANYInventors: Jonathan Lin, Joseph Trotter, Keegan Owsley
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Patent number: 11644408Abstract: An optical cell for performing light spectroscopy (including absorbance, fluorescence and scattering measurements) on a liquid sample in microfluidic devices is disclosed. The optical cell comprises an inlaid sheet having an opaque material inlaid in a clear material, and a sensing channel that crosses the clear material and the opaque material provides a fluidic path for the liquid sample and an optical path for probe light. Integral optical windows crossing a clear-opaque material interface permit light coupling into and out of the sensing channel, and thus light transmission through the sensing channel is almost entirely isolated from background light interference. A microfluidic chip comprising one or more optical cells is also disclosed. The optical cells may have different lengths of sensing channels, and may be optically and fluidly coupled. A method of manufacturing an optical cell in a microfluidic chip is also disclosed.Type: GrantFiled: November 10, 2021Date of Patent: May 9, 2023Assignee: DARTMOUTH OCEAN TECHNOLOGIES INC.Inventors: Edward Arthur Luy, Sean Christopher Morgan, Vincent Joseph Sieben
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Patent number: 11644409Abstract: Reusable network of spatially-multiplexed microfliuidic channels each including an inlet, an outlet, and a cuvette in-between. Individual channels may operationally share a main or common output channel defining the network output and optionally leading to a disposable storage volume. Alternatively, multiple channels are structured to individually lead to the storage volume. An individual cuvette is dimensioned to substantially prevent the formation of air-bubbles during the fluid sample flow through the cuvette and, therefore, to be fully filled and fully emptied. The overall channel network is configured to spatially lock the fluidic sample by pressing such sample with a second fluid against a closed to substantially immobilize it to prevent drifting due to the change in ambient conditions during the measurement. Thereafter, the fluidic sample is flushed through the now-opened valve with continually-applied pressure of the second fluid.Type: GrantFiled: March 8, 2022Date of Patent: May 9, 2023Assignee: The General Hospital CorporationInventors: Ramin Haghgooie, Kenneth T. Kotz, Robert Granier, Anne Celia Petrofsky
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Patent number: 11644410Abstract: The present invention provides systems, devices, and methods for point-of-care and/or distributed testing services. The methods and devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device can be modified to allow for more flexible and robust use with the disclosed methods for a variety of medical, laboratory, and other applications. The systems, devices, and methods of the present invention can allow for effective use of samples by improved sample preparation and analysis.Type: GrantFiled: December 28, 2020Date of Patent: May 9, 2023Assignee: Labrador Diagnostics LLCInventors: Anthony J. Nugent, Daniel L. Young, Elizabeth A. Holmes, Michael Siegel, Ryan Wistort
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Patent number: 11644411Abstract: A contamination sensor for an optical sensor observation window includes a source, two prisms, a detector, and a controller. The source can emit a collimated light beam at an incident angle that is greater than a critical angle of an interface between a fluid and the window. The window has a refractive index greater than the refractive index of the fluid. The prisms can direct the collimated light beam within the window such that the collimated light beam reflects within a contamination detection zone of the window. The detector can receive the collimated light beam. The controller can communicate with the source and detector. The controller can calculate an emission/detection ratio defined by a difference between an amount of light emitted by the source and an amount of light that passes from the source to the detector by a total internal reflectance of the window.Type: GrantFiled: June 17, 2021Date of Patent: May 9, 2023Assignee: Rosemount Aerospace Inc.Inventor: Gary Halama
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Patent number: 11644412Abstract: A method and device of thin film spectroellipsometric imaging are disclosed. The device comprises an illuminator to direct light through a polarization generator system toward an extended area of a sample; an imaging system to form images; a detection system to record in a plurality of spectral channels; a computer to display and analyze the recorded images; and at least one reference phantom with known optical properties to replace the sample for calibration. The method comprises directing light from an illuminator through a polarization generator system toward an extended area of a sample having a geometrical shape; forming images with an imaging system; adjusting a polarization generator system and a polarization analyzer system to obtain a series of polarimetric setups; recording the images with a detection system in a plurality of spectral channels; replacing the sample with at least one reference phantom; and analyzing the recorded images with a computer.Type: GrantFiled: August 2, 2020Date of Patent: May 9, 2023Inventor: Aizhong Zhang
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Patent number: 11644413Abstract: The disclosure relates to a method for measuring a dielectric tensor of a material. Firstly, a partial conversion matrix Tp and a transmission matrix Tt are determined by a predetermined initial value ?(E) of the dielectric tensor of the material to be measured, thereby obtaining a transfer matrix of an electromagnetic wave on a surface of the material to be measured by the partial conversion matrix Tp, the transmission matrix Tt, and an incident matrix Ti, a theoretical Mueller matrix spectrum MMCal(E) of the material to be measured is determined by the transfer matrix Tm. A fitting analysis is performed on the theoretical Mueller matrix spectrum MMCal(E) and a measured Mueller matrix spectrum MMExp(E) of the material to be measured to obtain the dielectric tensor of the material to be measured.Type: GrantFiled: May 15, 2020Date of Patent: May 9, 2023Assignee: HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGYInventors: Honggang Gu, Baokun Song, Shiyuan Liu, Zhengfeng Guo, Mingsheng Fang, Hao Jiang, Xiuguo Chen
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Patent number: 11644414Abstract: The present disclosure relates to a ferrocene-based compound having high selectivity for sulfide ion. The ferrocene-based compound is obtained by reacting a ferrocene starting material with one or more organic compound selected from a nitrile, a methyl ester and an ethyl ester, and a chemical sensor in solution state is prepared by mixing the compound with an organic solvent. The chemical sensor according to the present disclosure has high selectivity and sensitivity for sulfide ion even at low concentration and may be used as a chemical sensor for detecting hydrogen sulfide in solution state by allowing visual inspection of sulfide ion.Type: GrantFiled: March 2, 2021Date of Patent: May 9, 2023Assignee: REPUBLIC OF KOREA (NATIONAL FORENSIC SERVICE DIRECTOR MINISTRY OF INTERIOR AND SAFETY)Inventors: Dae-Jun Ahn, Mia Kwon, Jisook Min, Joon-Bae Lee, Dong-Kye Lee, Byeong-Yeol Song
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Patent number: 11644415Abstract: Provided is a system for measuring gas temperature and component concentrations in a combustion field based on optical comb. The system includes two pulse laser devices, two continuous laser devices, a beam splitting device, a measurement path, an interference signal detecting device, an optical processing and electrical processing device and a signal acquisition and analysis device. The measurement path refers to the combustion field to be measured. The interference signal detecting device outputs an interference signal. The optical processing and electrical processing device includes several optic elements and electrical elements, and outputs an adaptive compensation signal and an asynchronous sampling clock signal after a series of processing on output of the two pulse laser devices and two continuous laser devices. The signal acquisition and analysis device outputs the measurement result based on the adaptive compensation signal, the asynchronous sampling clock signal and a stable interference signal.Type: GrantFiled: February 17, 2021Date of Patent: May 9, 2023Assignees: CHONGQING INSTITUTE OF EAST CHINA NORMAL UNIVERSITY, ROI OPTOELECTRONICS TECHNOLOGY CO, LTD., EAST CHINA NORMAL UNIVERSITY, UNIVERSITY OF SHANGHAI FOR SCIENCE AND TECHNOLOGYInventors: Heping Zeng, Kangwen Yang, Hai Li
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Patent number: 11644416Abstract: An artificial intelligence model receives a FTIR spectrum of a given ingredient to predict its protein secondary structure. The model includes three artificial modules, which generate three predicted values corresponding to structural categories (e.g., ?-helix, ?-sheet, and other) of the predicted secondary structure. Proteins may be compared for similarity based on predicted values corresponding to the structural categories of the predicted secondary structure.Type: GrantFiled: February 19, 2021Date of Patent: May 9, 2023Assignee: NotCo Delaware, LLCInventors: Nathan O'Hara, Adil Yusuf, Julia Christin Berning, Francisca Villanueva, Rodrigo Contreras, Isadora Nun, Aadit Patel, Karim Pichara
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Patent number: 11644417Abstract: Provided is a gas detection apparatus which suppresses occurrences of distortions of the optical path to reduce fluctuations of the gas detection sensitivity. A gas detection apparatus 1 includes a substrate 2; a light emitting element 3 disposed in a first region 21 in a main surface 20 of the substrate 2 for emitting light; a light receiving element 4 disposed in a second region 22 in the main surface 20 of the substrate 2 for receiving the light; a light guide member 5 for guiding the light emitted by the light emitting element 3 to the light receiving element 4; and a joint member 6 joining the substrate 2 and the light guide member 5. The joint member 6 serves as a rotation axis when the light guide member 5 is displaced relative to the substrate 2.Type: GrantFiled: March 4, 2021Date of Patent: May 9, 2023Assignee: Asahi Kasei Microdevices CorporationInventors: Yuji Ikeda, Keiichiro Kuwata, Takaaki Furuya
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Patent number: 11644418Abstract: The present invention provides a far-infrared light source capable of reducing the shift in the location irradiated with far-infrared light even when the frequency of the far-infrared light changes. A far-infrared light source according to the present invention is configured so that the variation in the emission angle of far-infrared light in a nonlinear optical crystal when the frequency of the far-infrared light changes is substantially offset by the variation in the refractive angle of the far-infrared light at the interface between the nonlinear optical crystal and a prism when the frequency of the far-infrared light changes (see FIG. 8).Type: GrantFiled: August 23, 2021Date of Patent: May 9, 2023Assignee: Hitachi High-Tech CorporationInventors: Kei Shimura, Mizuki Mohara, Kenji Aiko
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Patent number: 11644419Abstract: A method for optical inspection includes illuminating a patterned polymer layer on a semiconductor wafer with optical radiation over a range of infrared wavelengths, measuring spectral properties of the optical radiation reflected from multiple points on the patterned polymer layer over the range of infrared wavelengths, and based on the measured spectral properties, computing a complex refractive index of the patterned polymer layer.Type: GrantFiled: January 28, 2021Date of Patent: May 9, 2023Assignee: KLA CorporationInventors: Roie Volkovich, Liran Yerushalmi, Amnon Manassen, Yoram Uziel
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Patent number: 11644420Abstract: A system, comprising a processor and a memory. The memory stores instructions executable by the processor to determine, from an image including a portion of a surface of a human body, a reflected light intensity from the body surface portion, determine, a skin reflectance of the body surface portion based on a location of the body surface, a light source, and an image sensor location, and to determine, for the body surface portion, an incoming radiance, based on the skin reflectance and the reflected light intensity.Type: GrantFiled: October 22, 2020Date of Patent: May 9, 2023Assignee: Ford Global Technologies, LLCInventors: Avrokin Surnilla, David Michael Herman, John Craig Elson, Scott Andrew Amman, Nikhitha Bekkanti, Michael Monforton
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Patent number: 11644421Abstract: A down-converted light emitting combination that generates a visible light when an ultraviolet light is incident is provided. The down-converted light emitting combination includes a first structure made of a first material that generates a visible light of a first color when an ultraviolet light of a first wavelength range is incident and a second structure made of a second material that generates a visible light of a second color different from the first color when the ultraviolet light of a second wavelength range different from the first wavelength range is incident, and the first material and the second material have different emission colors and distributions of intensities of the visible lights generated depending on a wavelength of the incident ultraviolet light.Type: GrantFiled: August 20, 2020Date of Patent: May 9, 2023Assignee: Korea University Research and Business FoundationInventors: Woong Kim, Sungnam Park, Wonbae Sohn, Gangyeol Yoo, Chiho Lee
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Patent number: 11644422Abstract: A calibration standard for determining an intensity decay related to an evanescent field generated close to the interface between a sample to be tested and a substrate on which the sample is to be deposited, preparation and analysis methods and use thereof.Type: GrantFiled: September 12, 2019Date of Patent: May 9, 2023Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE DE PARIS, UNIVERSITE BAR-ILANInventors: Martin Oheim, Adi Salomon
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Patent number: 11644423Abstract: An optochemical sensor unit including: an optical waveguide; a transmitting unit for emitting a first transmission signal for exciting a luminophore; a receiving unit for receiving a received signal comprising a signal component emitted by the excited luminophore; a measuring chamber for receiving a fluid, wherein the fluid includes magnetic microspheres; a membrane arranged between the measuring chamber and a measuring medium for exchanging an analyte between the measuring medium and the fluid in the measuring chamber, wherein the measuring diaphragm is impermeable to the magnetic microspheres; and an electromagnet for attracting magnetic microspheres to a sensor membrane with a fluid-contacting surface and/or to a fluid-contacting surface of the optical waveguide, or to a surface of a transparent substrate layer of the optical sensor unit that is connected to the optical waveguide.Type: GrantFiled: November 10, 2020Date of Patent: May 9, 2023Assignee: Endress+Hauser Conducta GmbH+Co. KGInventor: Andreas Löbbert
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Patent number: 11644424Abstract: An interferometric method and apparatus for the non-invasive assessment of oocyte maturity and competency. The method includes placing an oocyte in a sample holder to provide a biological target; generating a near infrared light; using a beam splitter to split the near infrared light into a signal light portion and a reference light portion; projecting the signal light portion onto the biological target; collecting reflected and back scattered light from the signal light portion projected onto the biological target with a detector; collecting at least a portion of the reference light portion with the detector; generating interferometric image data based upon the collected signal and reference light; and assessing the maturity of the oocyte based upon the interferometric data while maintaining the viability of the oocyte. When the oocyte is part of a cumulus-oocyte complex, the assessment is accomplished without removing cumulus cells from the cumulus-oocyte complex while maintaining viability.Type: GrantFiled: April 27, 2020Date of Patent: May 9, 2023Assignee: Waverly Industries, LLCInventors: Ran An, Gayatri Narayanan, Travis A. Morgan, Theodore R. Schenberg
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Patent number: 11644425Abstract: A data processing device includes an internal volume that is electromagnetic interference (EMI) isolated and an optical state detector. The optical state detector obtains electromagnetic radiation from the internal volume while the internal volume is EMI isolated and makes a determination that a device disposed in the internal volume has an optical state associated with the electromagnetic radiation.Type: GrantFiled: July 19, 2019Date of Patent: May 9, 2023Assignee: Dell Products L.P.Inventors: Steven Embleton, Ben John Sy, Eric Michael Tunks
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Patent number: 11644426Abstract: Disclosed herein is a computer-implemented method for generating calibration data usable for analysis of a sample. The method includes: (i) identifying targets in an image frame pertaining to a scanned area of a sample; (ii) computing displacements of the targets relative to positions thereof as given by, or derived from, reference data of the scanned area; (iii) based at least on the computed target displacements, determining values of coordinate transformation parameters (CTPs) relating coordinates of the image frame to coordinates of the scanned area as given by, or derived from, the reference data; and (iv) using at least the CTPs to obtain displacements of multiple segments in the image frame, thereby generating a displacement mapping of the image frame or at least a part thereof.Type: GrantFiled: August 11, 2020Date of Patent: May 9, 2023Assignee: Applied Materials Israel Ltd.Inventor: Yariv Simovitch
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Patent number: 11644427Abstract: An automatic detection method and an automatic detection system for detecting any crack on wafer edges are provided. The automatic detection method includes the following steps. Several wafer images of several wafers are obtained. The wafer images are integrated to create a templet image. Each of the wafer images is compared with the templet image to obtain a differential image. Each of the differential images is binarized. Each of the differential images which are binarized is de-noised. Whether each of the differential images has an edge crack is detected according to pattern of each of the differential images which are de-noised.Type: GrantFiled: November 23, 2020Date of Patent: May 9, 2023Assignee: UNITED MICROELECTRONICS CORP.Inventors: Chia-Feng Hsiao, Chung-Hsuan Wu, Shuo-Yu Chen, Nai-Ying Lo, Yi-Hui Tseng, Chen-Hui Huang, Yung-Yu Yang, Tzu-Ping Kao
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Patent number: 11644428Abstract: Systems, methods, and apparatus are provided for determining overlay of a pattern on a substrate with a mask pattern defined in a resist layer on top of the pattern on the substrate. A first grating is provided under a second grating, each having substantially identical pitch to the other, together forming a composite grating. A first illumination beam is provided under an angle of incidence along a first horizontal direction. The intensity of a diffracted beam from the composite grating is measured. A second illumination beam is provided under the angle of incidence along a second horizontal direction. The second horizontal direction is opposite to the first horizontal direction. The intensity of the diffracted beam from the composite grating is measured. The difference between the diffracted beam from the first illumination beam and the diffracted beam from the second illumination beam, linearly scaled, results in the overlay error.Type: GrantFiled: December 18, 2019Date of Patent: May 9, 2023Assignee: ASML Netherlands B.V.Inventor: Arie Jeffrey Den Boef
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Patent number: 11644429Abstract: A method for calculating a laminate state of a CFRP laminate according to an embodiment includes acquiring a plurality of images of a cross section of the CFRP laminate orthogonal to a lamination direction by imaging the CFRP laminate with X-rays at a plurality of different positions in the lamination direction, the CFRP laminate including first layers including carbon fibers oriented in a first direction orthogonal to the lamination direction and second layers including carbon fibers oriented in a second direction orthogonal to the lamination direction and different from the first direction, and calculating a parameter correlated with a quantity of voids formed in the first layers and the second layers from the plurality of acquired images, and distinguishing between the first layers and the second layers using the calculated parameter.Type: GrantFiled: April 27, 2021Date of Patent: May 9, 2023Assignee: TOYOTA JIDOSHA KABUSHIKI KAISHAInventors: Takuya Omoto, Yuzo Miura, Yuichi Nagamatsu
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Patent number: 11644430Abstract: A high-sensitive phase imaging is achieved using a grating section without upsizing the imaging device or narrowing the period of the gratings. A radiation source generates radiation on a radiation path toward the grating section. The grating section comprises a G1 grating and a refraction-enhancing grating. The G1 grating has a G1 periodic structure that forms radiation converging points where an intensity of the radiation is increased between the G1 grating and a detector. The refraction-enhancing grating is located at the position of the radiation converging points and has enhancement planes and that increase the refraction angle of the radiation. The detector detects the radiation that has passed through the grating section.Type: GrantFiled: January 24, 2020Date of Patent: May 9, 2023Assignee: Tohoku UniversityInventor: Atsushi Momose
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Patent number: 11644431Abstract: Disclosed is a measurement probe for a measurement of elements in a mineral slurry. The measurement probe includes a housing having an X-ray window. The housing encloses: an X ray source positioned to emit source X-rays at the X-ray window; an X-ray detector positioned to detect X-rays from the X-ray window; and a control module. The control module is configured to: control an operation of the X-ray source and the X-ray detector; process X-rays detected by the X-ray detector to generate X-ray spectra data; and process the X-ray spectra data to determine a quantity of one or more elements of interest in the mineral slurry. The measurement probe further includes a probe mount adapted to couple the measurement probe to a pipe mount on a pipe carrying the mineral slurry; when the probe mount is coupled to the pipe mount, the X-ray window provides a transmission window for X-rays into a lumen of the pipe.Type: GrantFiled: August 15, 2019Date of Patent: May 9, 2023Assignee: Microtrace Pty LimitedInventor: Gregory John Roach
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Patent number: 11644432Abstract: Methods of determining thermal properties of a contact region are provided. The method comprises receiving temperature data of a sensor; determining a temperature distribution of heat penetration from a sensor to at least one material; applying a correction to the temperature distribution; iteratively analyzing the corrected temperature distribution; and outputting thermal properties of a contact region, the contact region being a region between the sensor and the at least one material. The method may further comprise determining thermal properties of the at least one material; and determining corrected thermal properties of the material using the thermal properties of the contact region. The method may further comprise automatically determining an appropriate time window for measuring properties of the at least one material to minimize effects of the contact region.Type: GrantFiled: June 16, 2020Date of Patent: May 9, 2023Assignee: Thermtest, Inc.Inventors: Dale Hume, David Landry, Andrew Evans
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Patent number: 11644433Abstract: The invention discloses an impedance spectrum in-situ measuring device for the dielectric constant of solid materials at high temperature and high pressure conditions. The device comprises a cube-shaped pyrophyllite, a cylindrical opening penetrates between one end face of the pyrophyllite and the other end face opposite to the end face; a heater formed by sleeving annular stainless steel sheets is arranged in the opening; a first plate-shaped platinum electrode and a second plate-shaped platinum electrode are arranged in the cavity of the innermost ring-shaped stainless steel sheet. The first plate-shaped platinum electrode is electrically connected with one end of the Solartron 1260 Impedance/Gainphase Analyzer through a first lead, and the second plate-shaped platinum electrode is electrically connected with the other end of the Solartron 1260 Impedance/Gainphase Analyzer through a second lead.Type: GrantFiled: January 18, 2022Date of Patent: May 9, 2023Assignee: Institute of Geochemistry, Chinese Academy of ScienInventors: Shuangming Shan, Heping Li
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Patent number: 11644434Abstract: Methods and biosensor systems for compensating an analyte measurement are provided. The methods and systems determine a secondary output signal based on the measured primary output signal in order to better approximate the effects of an extraneous stimulus on the primary output signal under actual measurement conditions. The methods and systems according to the present disclosure may provide a more accurate analyte measurement, and may be particularly useful in detecting and compensating an analyte measurement during an off-condition.Type: GrantFiled: May 13, 2016Date of Patent: May 9, 2023Assignee: Ascensia Diabetes Care Holdings AGInventor: Huan-Ping Wu
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Patent number: 11644435Abstract: A DNA sequencing device and methods of making. The device includes a pair of electrodes having a spacing of no greater than about 2 nm, the electrodes being exposed within a nanopore to measure a DNA strand passing through the nanopore. The device can be made by depositing a conductive layer over a sacrificial channel and then removing the sacrificial channel to form the electrode gap.Type: GrantFiled: April 10, 2020Date of Patent: May 9, 2023Assignee: SEAGATE TECHNOLOGY LLCInventors: ShuaiGang Xiao, David S. Kuo, Xiaomin Yang, Kim Yang Lee, Yautzong Hsu, Michael R. Feldbaum
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Patent number: 11644436Abstract: The present disclosure provides a particle analyzer and a particle test control method and device thereof. A method comprises, acquiring a blood sample in a test location; preparing a diluted sample by the acquired sample; after acquiring a diluted sample, monitoring whether a pore blocking event occurs during a counting process; when the pore blocking event occurs, suspending the test of the sample, and performing an unblocking operation; and after the unblocking operation is completed, re-counting the same diluted sample without re-acquiring and re-diluting the blood sample by the impedance method after the unblocking operation.Type: GrantFiled: March 26, 2020Date of Patent: May 9, 2023Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.Inventors: Tao Shen, Huilin Shi, Jin Teng, Wenheng Guo
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Patent number: 11644437Abstract: There is provided a nanopore sensor including cis and trans fluidic reservoirs. A nanopore is provided in a support structure separating the cis and trans reservoirs. The nanopore has an inlet in fluidic connection with the cis fluidic reservoir and an outlet in fluidic connection with the trans fluidic reservoir. The cis fluidic reservoir has a fluidic access resistance, RC, the trans fluidic reservoir has a fluidic access resistance, RT, and the nanopore has a fluidic resistance, RP. RP is of the same order of magnitude as RT and both RP and RT are at least an order of magnitude greater than RC. An electrical transduction element is disposed at a nanopore sensor site that exposes the transduction element to the trans reservoir. An electrical circuit is connected to the electrical transduction element for producing an electrical signal indicative of changes in electrical potential local to the trans reservoir.Type: GrantFiled: June 14, 2021Date of Patent: May 9, 2023Assignee: President and Fellows of Harvard CollegeInventors: Ping Xie, Charles M. Lieber
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Patent number: 11644438Abstract: A capillary cartridge achieves both improvement of attachability and improvement of heat dissipation performance for realizing short-time analysis. A heat dissipation body is provided between a capillary having a detection unit provided in a part thereof and a plate-like support body that supports the capillary, and temperature increase inside the capillary is suppressed by the heat dissipation body, and thereby, electrophoresis can be performed under a high voltage application condition where the amount of heat increases and analysis time is reduced. In addition, it is possible to redress complexity of an operation by reducing a fixing place at the time of attachment to only a detection unit and an electrode holder by using an integration structure in which the capillary, the supporting body, and the heat radiating body are integrated.Type: GrantFiled: February 5, 2021Date of Patent: May 9, 2023Assignee: Hitachi High-Tech CorporationInventors: Ayaka Okuno, Motohiro Yamazaki, Taro Nakazawa, Mitsuhiro Miyazaki, Ryusuke Kimura
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Patent number: 11644439Abstract: A magnetic body inspection apparatus includes a magnetic field application unit configured to apply a magnetic field to a long material including a magnetic body to be inspected, a detector configured to excite, in a longitudinal direction of the long material, magnetization of the magnetic body, the detector being configured to acquire a detection signal based on the magnetic field of the magnetic body that has been excited, and a detection apparatus body including the magnetic field application unit and the detector, the detection apparatus body being configured to be attachable to the long material in a short-side direction of the long material.Type: GrantFiled: January 16, 2020Date of Patent: May 9, 2023Assignee: SHIMADZU CORPORATIONInventor: Kenji Iijima