Abstract: The present invention relates to a process for treating a plastics pyrolysis oil, comprising: a) selective hydrogenation of said feedstock in the presence of at least hydrogen and of at least one selective hydrogenation catalyst; b) hydrotreatment of said hydrogenated effluent in the presence of at least hydrogen and of at least one hydrotreatment catalyst, to obtain a hydrotreated effluent; c) hydrocracking of said hydrotreated effluent in the presence of at least hydrogen and of at least one hydrocracking catalyst, to obtain a hydrocracked effluent; d) separation of the hydrocracked effluent in the presence of an aqueous stream, at a temperature of between 50 and 370° C., to obtain at least one gaseous effluent, an aqueous liquid effluent and a hydrocarbon-based liquid effluent.

Abstract: The present invention relates to a process for treating an SRF and/or plastics pyrolysis oil, comprising: a) optionally, selective hydrogenation of the feedstock; b) hydroconversion in an ebullated bed, in an entrained bed and/or in a moving bed, to obtain a hydroconverted effluent; c) separation of the hydroconverted effluent in the presence of an aqueous stream, to obtain a gaseous effluent, an aqueous liquid effluent and a liquid hydrocarbon effluent; d) fractionation of the liquid hydrocarbon effluent to obtain at least one gas stream and a cut with a boiling point of less than or equal to 385° C. and a cut with a boiling point above 385° C.; e) hydrotreatment of said cut comprising compounds with a boiling point of less than or equal to 385° C. to obtain a hydrotreated effluent; f) separation to obtain at least a gaseous effluent and a hydrotreated liquid hydrocarbon effluent.

Abstract: A system for upgrading heavy hydrocarbon feeds, such as crude oil, include a hydrotreating unit, a hydrotreated effluent separation system, a solvent-assisted adsorption system, and a hydrocracking unit. Processes for upgrading heavy hydrocarbon feeds include hydrotreating the hydrocarbon feed to produce a hydrotreated effluent that includes asphaltenes, separating the hydrotreated effluent into a lesser boiling hydrotreated effluent and a greater boiling hydrotreated effluent comprising the asphaltenes, combining the greater boiling hydrotreated effluent with a light paraffin solvent to produce a combined stream, adsorbing the asphaltenes from the combined stream to produce an adsorption effluent, and hydrocracking the lesser boiling hydrotreated effluent and at least a portion of the adsorption effluent to produce a hydrocracked effluent with hydrocarbons boiling less than 180° C. The systems and processes increase the hydrocarbon conversion and yield of hydrocarbons boiling less than 180° C.

Abstract: A plasma processing method for a gas comprises supplying a gas inside a cavity for plasma processing, supplying microwaves having a predetermined frequency and power in order to generate a plasma of the gas, and propagating the microwaves in the gas by means of a waveguide which communicates directly with the cavity so as to provide a plasma cracking processing operation for the gas inside the cavity (2).

Abstract: A low friction wear surface with a coefficient of friction in the superlubric regime under a sliding and rolling movement. The low friction wear surface includes molybdenum disulfide and graphene oxide on a first wear surface with a tribolayer formed on a rough steel counter surface during the sliding and rolling movement. Methods of producing the low friction wear surface are also provided.

Abstract: A lubricating oil composition may have a high flash point, a low pour point, and excellent electrical insulation, while having excellent cooling performance. Such a lubricating oil composition may include a base oil (A), wherein the base oil (A) includes at least one synthetic oil (A1) selected from a polyalkylene glycol having a specific degree of polymerization and a polyvinyl ether having a specific degree of polymerization.

Abstract: The present patent application relates to a method for reducing wear and tear on mechanical parts that are in contact with each other in an internal combustion engine by using a lubricating composition comprising: at least one base oil; at least one oxothiomolybdate salt; and at least one anti-wear compound; wherein at least one of the said parts includes a surface that comprises an amorphous carbon type coating.

Abstract: The present invention relates to a grease composition including: a base oil; a thickener; a rust inhibitor; and an extreme pressure agent, in which the rust inhibitor includes, with respect to a total mass of the grease composition: 0.10 mass % to 10.00 mass % of a calcium sulfonate; 0.20 mass % to 10.00 mass % of a zinc sulfonate; and 0.10 mass % to 10.00 mass % of a zinc carboxylate, and the extreme pressure agent includes, with respect to the total mass of the grease composition, 2.00 mass % to 14.00 mass % of a zinc dialkyldithiophosphate.

Abstract: The present invention describes a pipe sealing compound/adjunct lubricant used to prevent gas or liquid leaks when applied to pipe threads and other connections of the same. The compound relies on silicone oil lubricant(s) and one or more friction modifier(s), viscosity builder(s) and filler material(s). The compound contains a viscoelastic liquid that does not have a curing phase and is resistant to hardening and/or drying. The compound is chemically resistant to a wide variety of liquids and gases, is food safe and can withstand extreme high or low temperatures and precipitous temperature fluctuations. The compound has been found to exhibit an inverse pressure to leak rate phenomena.

Abstract: A lubricant composition includes (a) a hydrocarbon oil including at least 30%wt of isoparaffins, based on the total weight of the hydrocarbon oil, and (b) an alkoxylated natural oil. A method of using the lubricant composition in a water- based composition, in particular a water-based mud, to improve the lubricity and/or to reduce the foaming properties of the water-based composition is also disclosed.

Abstract: Present invention relates to process for reducing MOSH and/or MOAH content from vegetable oil selected from the group consisting of palm-based oil, cocoa butter-based oil and any mixture thereof, and comprising steps of: a) Subjecting vegetable oil to short-path evaporation being performed at a pressure of below 1 mbar and under further processing conditions either: a1) at an evaporator temperature of between 210 and 240° C., and with a feed rate per unit area of evaporator surface of the shorth-path evaporation equipment of from 35 to 105 kg/h·m2, or a2) at an evaporator temperature of from 245 to 300° C., and with a feed rate per unit area of evaporator surface of the shorth-path evaporation equipment of from 110 and 170 kg/h·m2, b) Contacting the retentate vegetable oil with an adsorbent, and c) Subjecting the bleached retentate vegetable oil to a further refining step.

Abstract: Present invention relates to process for reducing content of MOSH and/or MOAH from vegetable oil selected from group consisting of palm-based oil, cocoa butter-based oil and any mixture thereof, wherein process is comprising step of subjecting vegetable oil to short-path evaporation, wherein short-path evaporation is performed at pressure of below 1 mbar and further processing conditions either: a1) at evaporator temperature of between 210 and 240° C., and with a feed rate per unit area of evaporator surface of the shorth-path evaporation equipment of from 35 to 105 kg/h·m2, or a2) at evaporator temperature of from 245 to 300° C., and feed rate per unit area of evaporator surface in range of from 110 and 170 kg/h·m2, and thus obtaining a retentate vegetable oil and a distillate. Present invention further relates to use of short-path evaporation for reducing content of MOSH and/or MOAH from vegetable oil.

Abstract: A method of extracting essential oil from plant matter for personal use includes positioning an amount of medicinal herb in a mini oven. A heating element is at least partially covered by a metallic heat exchanger and positioned in the mini oven. The medicinal herb is pyrolysized by energizing the heating element. Vaporized essential oil from the medicinal herb is moved out of the mini oven and toward the user. Oxygen is displaced from the mini oven responsive to decarboxylation of the medicinal herb, to inhibit combustion at elevated temperatures.

Abstract: A cleaning liquid contains water, a specific organic solvent, and an acetylene surfactant. The specific organic solvent is at least one selected from the group consisting of polyhydric alcohol and polyalkylene glycol. The specific organic solvent has a percentage content of at least 1% by mass and no greater than 18% by mas to the mass of the cleaning liquid. The acetylene surfactant has a percentage content of at least 0.3% by mass and no greater than 1.0% by mass to the mass of the cleaning liquid.

Abstract: The present invention relates to the use of propoxylated methyl isobutyl carbinol or propoxylated di-isobutyl carbinol in cleaning compositions. In particular, the use of said carbinols provides improvement in cleaning performance for cleaning hard and soft surfaces.

Abstract: Dishwashing detergents containing a metal complex of the general formula (I) (Aq+)p[Ms+Lm?](Xo?)r (I) and related methods.

Abstract: A liquid hand dishwashing detergent composition containing a cationically modified inulin compound, methods of making the liquid hand dishwashing detergent compositions, and methods of using said liquid hand dishwashing detergent compositions, which provide improved rinsing, solution feel, and finished product viscosity control.

Abstract: Provided is a cleaning composition containing ?-amylase which exhibits high specific activity at low temperatures. The cleaning composition comprises one or more proteins selected from the group consisting of the following (A), (B), (C), and (D): (A) a protein consisting of an amino acid sequence having at least 90% identity to the amino acid sequence of SEQ ID NO: 2, and having ?-amylase activity; (B) a protein consisting of an amino acid sequence having at least 90% identity to the amino acid sequence of SEQ ID NO: 4, and having ?-amylase activity; (C) a protein consisting of an amino acid sequence having at least 90% identity to the amino acid sequence of SEQ ID NO: 6, and having ?-amylase activity; and (D) a protein consisting of an amino acid sequence having at least 90% identity to the amino acid sequence of SEQ ID NO: 8, and having ?-amylase activity.

Abstract: Home care compositions including a surfactant and an amylase. The amylase includes a recombinant, non-naturally-occurring variant of a parent alpha-amylase, the variant alpha-amylase having at least about 80% identity to SEQ ID NO: 5 and having amino acid substitutions at positions 415 and/or 51 with respect to SEQ ID NO: 5.

Abstract: A laundry scent additive having polyethylene glycol and perfume. The laundry scent additive enables consumers to control the amount of scent imparted to their laundry.

Abstract: A method of making a non-fibrous laundry detergent sheet can include dispensing a microcapsule onto a precursor non-fibrous laundry detergent sheet, wherein the precursor non-fibrous laundry detergent sheet can include: (a) at least one surfactant; (b) at least one film former; and (c) a thickness ranging from 0.1 mm to 10 mm.

Abstract: The present invention relates to a cleaning or soap product, in particular personal care product, in particular hand washing soap, comprising a first chemical and/or mechanical mechanism for generating a first color transition of the cleaning or soap product, and a second chemical and/or mechanical mechanism for generating a second color transition. Numerous embodiments and chemical-technical variants of the invention are disclosed.

Abstract: The invention relates to a self-cleaning homogeneous mixer-bleeder system composed of a set of screens and a bleed manifold (1), in particular for the production of must by pellicular maceration, of the type incorporated in a wine maceration tank (0) and having mainly: a. a bleed system (10) containing a bleed manifold (107) and a set of perforated side bleed screens (102); b. an inerting valve (11); c. a CO2 system (12).

Abstract: The invention relates to a bottled sparkling white wine and to the method for producing same. The bottled wine contains a measured amount of an opacifying agent that does not alter the organoleptic properties of the wine; said measured amount, added prior to final corking of the bottle, consists of a suspension of finely divided oenological activated carbon in a food-grade liquid.

Abstract: Process for recovering at least one fractional substance from vapours during the alcohol reduction of a beverage, and fractional substance recovery device for carrying out the process, in which an alcoholic beverage to be reduced in alcohol content is supplied to a degasser of a fractional substance recovery device, in which vapours are removed from the degasser and the alcoholic beverage passed through the degasser is supplied to a device for alcohol reduction, in which the vapours are fed to a plurality of fractional condensation stages which follow one another in series and in which at least one fractional substance is separated from the vapours under pressure and/or temperature, and in which the fractional substances separated in the respective fractional condensation stage are collected in a collecting container or are fed to an inoculation station, through which the separated fractional substances are fed in metered quantities to an alcohol-reduced drink.

Abstract: The photoreactor system includes a chamber, a lid, a catalyst coating, and an oxygen supply port. The photoreactor system is configured to process a sample by breaking down organic molecules, such as Tetrahydrocannabinol (THC). The catalyst coating is coupled to an interior surface of the chamber. The photoreactor system includes a mixing blade to agitate the sample. The chamber also includes a baffle substantially covered with the catalyst coating to enhance the turbulent flow of the sample and provide more catalyst coated surface area within the chamber.

Abstract: The present disclosure relates to a substrate apparatus (and methods of manufacturing the same) with one or more substrates having a substrate spacing for growing a cell mass. In particular embodiments, the disclosed substrate apparatus includes a substrate wound into a coiled configuration with an intra-coil spacing between coil layers. To provide the intra-coil spacing, certain implementations use a separator. For example, a separator is applied to a substrate surface, and the separator-substrate combination is wound together (e.g., around a spool). In turn, a locking element is attached to the substrate to maintain the coiled configuration. The separator is then removed via heat treatment, chemical treatment, or physical displacement—thereby leaving the intra-coil spacing between the coil layers. Alternatively, no separator is used to provide a substrate spacing. For example, in lieu of a separator, the locking element is actively applied to the substrate during the winding process.

Abstract: An exposure unit is used in order to expose a gas-phase substance to a cell in a buffer solution. The exposure unit includes a base body. The base body has a groove formed in the base body so as to be exposed to an outside and retaining the cell together with the buffer solution, and a first storage portion connected to one end of the groove and storing the buffer solution to be supplied to the groove.

Abstract: A well plate and a 3D cell culture plate are described. The well plate having a repeating pattern. The wells of the well plate is continuously provided with a space part in between a main well to be injected with culture solution and a sub well including a recessed part where the cells are cultured. The main well of the well plate is connected to the space part with forming a step, and the sub well is connected to the part with forming an inclined surface.

Abstract: Provided herein is an insert chip and a cell culture system including the same, adapted for culturing a plurality of cell populations under various flow patterns.

Abstract: Said brewing system is intended to be fitted to a bioreactor which can be used in particular in milk and cheese factories, fermented dough production units, breweries, wine-making units or even low-temperature fermentation units in an aerobic or anaerobic environment, in particular lacto-fermentation units for the purpose of preserving vegetables, wastewater treatment stations, fish farming ponds with or without temperature control. According to the invention, said brewing system comprises:—at least one flexible and sealed brewing chamber (2, 3),—means (4) for receiving a fluid referred to as the filling fluid,—means (5, 51, 70, 71) for transferring the filling fluid between the brewing chambers (2, 3), and means (4) for receiving the filling fluid as well as varying the volume of the filling fluid admitted into each brewing chamber.

Abstract: A cell culturing container including a fixed bed is provided for forming a bioreactor (100). In one version, a container in the form of a tubular body is formed by first and second interlocking portions (115a, 115b). The container forms a compartment for receiving the fixed bed (122) for culturing cells, which container may be removably inserted into an inner compartment of the bioreactor so as form an outer chamber for circulating fluid to or from the fixed bed. The container may also include a removable base (130) for receiving an agitator (118) for agitating and thus circulating the fluid. Related methods are also disclosed.

Abstract: An apparatus for culturing cells includes a bioreactor. The bioreactor may be modular and may include in a chamber a fixed bed, such as an unstructured or structured fixed bed (such as a spiral bed) for culturing cells, with a return column arranged centrally within the chamber. The modular bioreactor may include a plurality of structured fixed bed arranged in a stacked configuration. The modular bioreactor may include an outer casing forming a space for conditioning (e.g., insulating, heating, cooling) at least a chamber in which cells are cultured. The bioreactor may also include an impeller with radially curved blades, and may also suspend the impeller so that it may move from side-to-side and align with an external drive. Related methods are also disclosed.

Abstract: A multi-position support for a multi-layer cell culture apparatus includes a primary base that rests against a support member in an upright configuration. A support surface is offset vertically from the primary base in the upright configuration. The support surface supports the multi-layer cell culture apparatus with the multi-layer cell culture apparatus located thereon. An intermediate surface extends between the primary base and the support surface. The intermediate surface meets the primary base at an interface that extends at an oblique angle to sides of the primary base. The multi-position support has a tilted configuration where the multi-position support is rotated about the interface such that the support surface is closer to the support member than in the upright configuration with the support surface supporting the multi-layer cell culture apparatus thereon.

Abstract: Devices and systems for product transfer, such as a dissolvable microcarriers, are described. In one example, the product delivery device may include an inlet port; a conical section that may include a wide end and a narrow end; an outlet port flush with the narrow end of the conical section and extending away from the conical section; and a securement feature configured to connect the wide end of the conical section to a container. In another example, a system for aseptic dry product delivery may include a container at least partially filled with the aseptic dry product; a product delivery device; a pressure source connected to an inlet port; and a receiving vessel where the aseptic dry product is collected.

Abstract: Provided herein are injection molded perfusion-enabled bioreactors and systems including said bioreactors. The bioreactor can include a lid, a frame comprising an an-ay of sample wells, a membrane adhered to a bottom of the frame beneath the array of sample wells, and a skirt adhered to a bottom of the frame, such that the membrane is located between the frame and the skirt. The skirt can include a plurality of channels corresponding to the sample wells.

Abstract: The present disclosure relates to a bioreactor assembly having a housing defining an interior chamber; a lid assembly removably coupled to the housing and enclosing the interior chamber; and a gimbal assembly disposable within the interior chamber. The gimbal assembly includes a cradle configured to hold an organ or organ scaffold and an arm assembly configured to move the cradle between a plurality of positions. The bioreactor assembly also includes an ultrasound imaging unit positioned to capture volumetric and/or spatial data of the organ or organ scaffold.

Abstract: A substance introduction device introduces a substance into a cell by electroporation, and includes at least one substance introduction unit including an accommodation container that accommodates a cell suspension containing the cell and the substance and a pair of electrodes that applies a voltage to the cell suspension accommodated in the accommodation container; and a liquid delivery unit that delivers a liquid to the accommodation container. The accommodation container has a first and a second openings, and the liquid delivery unit fills the accommodation container with the cell suspension before voltage application through the first opening and to discharge the cell suspension after the voltage application from the accommodation container through the second opening, and to fill the accommodation container with a cleaning solution through the second opening and to discharge the cleaning solution from the accommodation container through the first opening.

Abstract: Provided are a novel evaluation system and an evaluation method for evaluating a state of cells. The evaluation system includes: a Raman spectroscopic device configured to perform Raman spectroscopic analysis on extracellular vesicles contained in a culture supernatant of the cells; and an analysis device configured to evaluate the state of the cells based on a Raman spectrum obtained by the Raman spectroscopic analysis.

Abstract: A method of controlling a cell culture process includes, for each time interval of one or more time intervals during the cell culture process, obtaining current values of one or more cell culture attributes associated with a cell culture, predicting one or more future values of a particular cell culture attribute associated with the cell culture, and controlling one or more physical inputs to the cell culture process. Predicting the future value(s) includes applying the current values of the cell culture attribute(s), and an earlier value of at least one of the cell culture attributes, as inputs to a data-driven predictive model using historical data. Controlling the physical input(s) includes applying the future value(s) as inputs to a model predictive controller.

Abstract: The present disclosure relates to a method of colony picking. The method includes the steps of mixing a bacterial suspension with an oil-based carrier liquid for generating a plurality of droplets comprising bacteria contained in the bacterial suspension and incubating the plurality of droplets for a predetermined period of time to allow growth of bacteria within the plurality of droplets. The method further includes the steps of screening each of the plurality of droplets that flows through one or more microfluidic channels of a microfluidic device to determine an opacity degree of each of the plurality of droplets, wherein the opacity degree is indicative of colony formation in the plurality of droplets, and sorting the plurality of droplets based on the opacity degree of each of the plurality of droplets.

Abstract: The present invention relates to the field of industrial fermentation. In particular, it relates to method for producing a protein of interest from a Bacillus host cell comprising the steps of inoculating a fermentation medium with a Bacillus host cell comprising an expression construct for a gene encoding a protein of interest, cultivating the Bacillus host cell in said fermentation medium under conditions conducive for the growth of the Bacillus host cell and the expression of the protein of interest for a cultivation phase, wherein the cultivation of the Bacillus host cell during said cultivation phase comprises the addition of at least one feed solution and wherein the at least one feed solution provides a carbon source, and separating portions from said Bacillus host cell culture during the cultivation phase at different time points and obtaining the protein of interest from said portions.

Abstract: Devices, and methods for preventing immune rejections are disclosed, in which trophoblasts or trophoblast-like cells are used to induce tolerance toward allogeneic cell and tissue grafts. The devices can be used as artificial placenta vaccines to avoid immunosuppression in organ transplantation.

Abstract: Various embodiments disclosed relate to conductive graphene matrix-encapsulated cells. A matrix-encapsulated cell includes an encapsulating polymer matrix including a biopolymer and graphene. The matrix-encapsulated cell also includes one or more of the cells encapsulated within the encapsulating polymer, wherein the graphene directly contacts at least some of the cells. The matrix encapsulating the one or more cells is electrically conductive.

Abstract: Methods of culturing cells capable of producing desired proteins to obtain the proteins by use of a medium from which biological components are excluded as much as possible are provided. Specifically, a culture method characterized by culturing while maintaining a specific amino acid in a culture solution at a high concentration, and a cell culture fed-batch medium for use in the method are provided.

Abstract: Described herein is an egg yolk extract comprising freed/lysed yolk granules and/or yolk spheres. Also described is an egg yolk extract comprising the liquid contents of a shelled egg, wherein the liquid contents comprise yolk granules. Also described are an egg yolk extract comprising the liquid contents of yolk spheres; an egg yolk extract comprising the liquid contents of yolk granules; an egg yolk extract comprising ovalbumin and other anti-bactericidal proteins in egg white; and an egg yolk extract that supports cell proliferation at least equivalent to FBS when used at the same concentration in a cell culture medium. Related supplements, media, and methods are also described.

Abstract: The invention relates to a process for producing carrier particles for the cultivation of biological cells, comprising the steps of providing an aqueous suspension of hydrogel beads and freeze-drying of the hydrogel beads so that dry hydrogel particles are formed, wherein at least one lyoprotectant substance is added to the suspension, the hydrogel beads are loaded in the suspension with the lyoprotectant substance and the dry hydrogel particles receive a shape under the effect of the lyoprotectant substance, which shape approximates a spherical particle shape and is still maintained after rehydrating. The invention also relates to carrier particles for a cultivation of biological cells, which comprise dry hydrogel particles, preferably having a protein coating, and to applications of the carrier particles.

Abstract: The present disclosure provides methods for generating retinal cell clusters for use in cellular component transfer therapy, retinal cell clusters generated by such methods, and compositions comprising such retinal cell clusters. The present disclosure also provides uses of the retinal cell clusters and compositions comprising thereof for preventing and/or treating inherited retinal degenerative diseases.

Abstract: The present disclosure provides compositions and methods for antigen identification. The methods provided herein comprise capturing polypeptides such as cytokines secreted by TCR-expressing cells (e.g., T cells) by antigen-presenting cells (APCs) presenting the antigens recognized by the TCRs of the TCR-expressing cells. The APCs can be detected or selected for antigen identification.

Abstract: Provided is an immune effector cell targeting FAP and another tumor-associated antigen, which can improve a tumor microenvironment, kill tumor cells, and can be used to treat tumors.