Abstract: A non-transitory, computer readable, storage medium stores a self-optometry control program that is executed by a first information processing device and includes a self-optometry program. The self-optometry program causes the first information processing device to perform executing a calling operation based on a calling instruction and setting an examination timing for an assistance operation such that the assistance operation starts from an examination item that was performed at a timing the calling instruction was inputted.

Abstract: Embodiments of the present disclosure are directed to systems, apparatuses and methods for prediction, diagnosis, planning and monitoring for myopia and myopic progression. In some embodiments, one or more refractive properties of the eye is determined for each of a plurality of retinal locations of the eye. The plurality of locations may comprise a central region, such as a fovea of the eye, or non-foveal region such as a peripheral region or a region of the macula outside the fovea. Measuring the refractive properties of the eye for the plurality of locations may be helpful in diagnosing myopia and other ocular conditions by providing the refractive properties of the eye for locations away from the fovea, such as the peripheral retina.

Abstract: In view of the problem of specifying an arrangement and a method by means of which an eye can be measured preferably without artifacts and quickly, an arrangement for measuring an eye (1), comprising a light source (2) which is suitable for emitting light rays (3, 4) to the cornea (5) of an eye (1) and a control unit (6) which drives the light source (2) to emit the light rays (3, 4) and is suitable for converting reflected light rays (3a, 4a, 4b) entering the arrangement into signals (7, 8), is characterized in that the light source (2) when driven by the control unit (6) emits a central light ray (3) and emits a plurality of peripheral light rays (4) which are radially offset with respect to the central light ray (3) or in that the light source (2) when driven by the control unit (6) emits a plurality of peripheral light rays (4) radially offset with respect to one another, Moreover, a method is specified.

Abstract: A method to predict visual field loss includes defining a superior visual field as rows and columns in a coordinate system. The method further includes performing a display and record process for a first column of the columns by: initiating a base condition, initiating a recurrence condition, and initiating a stop condition when a difference between the new pivot point and a previous pivot point is less than a predetermined threshold. The method further includes repeating the display and record process for additional columns of the columns. The method further includes defining an eyelid meridian based on recorded coordinates for a set of points that are visible to the patient, calculating an area of the superior visual field based on the eyelid meridian, and determining the visual field loss based the area of the superior visual field.

Abstract: A method of determining pathologic myopia by using the geometric structure of a posterior sclera of a fundus includes obtaining geometric location data about a fovea, an optic disc, and a deepest point of the eye (DPE) in the posterior sclera of the fundus; obtaining an elevation difference TEPSfovea?DPE between the fovea and the DPE, an elevation difference TEPSdisc?DPE between the optic disc and the DPE, and an elevation difference TEPSfovea?disc between the fovea and the optic disc by using location information about the fovea, the optic disc, and the DPE in the posterior sclera; and determining pathologic myopia by using at least two elevation differences selected from among the elevation difference TEPSfovea?DPE between the fovea and the DPE, the elevation difference TEPSdisc?DPE between the optic disc and the DPE, and the elevation difference TEPSfovea?disc between the fovea and the optic disc.

Abstract: An ophthalmic device may include: a measurement optical system which includes a light-emitting optical system including a light source and a light-receiving optical system including a light receiving element; an arithmetic device configured to calculate an eye refractive power of the subject eye; a beam deflecting member arranged in an optical path of the measurement optical system and configured to deflect beam emitted from the light source, and a driving device configured to drive the beam deflecting member so that the beam emitted from the light source is scanned in a ring shape onto the subject eye. The beam deflecting member may be disposed so that traveling directions of the beam emitted from the light source intersect with each other between the subject eye and the beam deflecting member when the beam deflecting member is driven by the driving device.

Abstract: An information processing device for estimating an eyesight of a person, including circuitry configured to: obtain image data representing an image of an eye of the person; and estimate, based on the image data, the eyesight of the person.

Abstract: A system for determining a staining score of portions of dyeable epithelia within the ocular surface of a subject includes a portable computing device with a camera, a display, a memory, and a processor configured to execute a staining score application. An illumination/optics device with a light source and optics is configured to receive an image of the ocular surface. The illumination/optics device may be removably attached to the portable computing device. The staining score application includes an alignment module, an image acquisition module, and a staining scoring module.

Abstract: Provided is a biological sensor capable of easily determining a condition of a living body. A biological sensor according to the present technology includes: an irradiation system that irradiates a living body with irradiation light including light having a wavelength within a wavelength band including a peak wavelength related to absorption of water; a light receiving system that individually receives the light having the wavelength within the wavelength band out of light emitted from the irradiation system and reflected from each of a plurality of sites of the living body; and a processing system that determines a condition of the living body on the basis of statistics related to signals of the respective sites output from the light receiving system.

Abstract: Near Infrared Spectroscopy is employed to non-invasively detect blood glucose concentrations, in a multi-sensing detection device. A multi-layered artificial neural network is used to assess these relationships of non-linear interference from human tissue, as well as differences among individuals, and accurately estimate blood glucose levels. Diffuse reflectance spectrum from the palm at six different wavelengths analyzed with a neural network, results in a correlation coefficient as high as 0.9216 when compared to a standard electrochemical glucose analysis test.

Abstract: A method of stratifying precancerous tissues by their risk of becoming cancerous by using a machine learning algorithm in combination with hyperspectral imaging. Also a method of constructing the machine learning algorithm for stratifying precancerous tissues by risk.

Abstract: Provided is a simple, portable, real-time, and in vivo THz imaging device for imaging a target, e.g., a tooth in the subject. Moreover, the scanning based THz imaging device is much sufficiently sensitive as compared with the common X-ray imaging device. Therefore, the scanning based THz imaging device has the potential to operate in the density for early detection problems such as dental caries or demineralization of the enamel in the teeth. Also provided is a method for diagnosing or imaging the target in the subject by using the scanning based THz imaging device of the present disclosure.

Abstract: Systems and methods are provided for using rescan data in dental procedures, such as the preparation of orthodontics and prosthodontics. A method may include receiving scan data of a patient's teeth, demarcating useful data from data that should be replaced, receiving rescan data, and replacing at least a portion of the scan data that should be replaced with at least a portion of data from the rescan data.

Abstract: A temperature management apparatus includes at least one memory storing instructions, and at least one processor. The at least one processor is configured to execute the instructions to obtain visible light image data, obtain thermal image data having an imaging range corresponding to at least a part of the visible light image, identify a person included in the visible light image data and the thermal image data, obtain attribute information from a storage apparatus, obtain temperature information, based on the thermal image data, set a threshold, based on the attribute information, determine whether the body surface temperature of the person exceeds the threshold or not and output determination result information.

Abstract: The present invention provides a method of determining whether a subject is suffering or at a risk of developing a peripheral arterial disease via Positron Emitting Tomography (PET) imaging technology. The method comprises administering a PET radionuclide into the subject via automated generation and/or infusion system, performing PET scan of the region of interest, automated assessment of the PET images, performing assessment and suggesting the most appropriate therapeutic and/or management options for the patients based on the severity score, provides an assessment of regional lower proximity perfusion and perfusion reserve, and/or regional and mean standardized uptake values (SUVs). More particularly, the method of image processing identifies the regional differences in SMP (Skeletal muscle perfusion) and SMPR (Skeletal muscle perfusion reserve) across calf muscles at rest and cuff-induced hyperemia.

Abstract: The invention provides methods and systems for continuous noninvasive measurement of vital signs such as blood pressure (cNIBP) based on pulse arrival time (PAT). The invention uses a body-worn monitor that recursively determines an estimated PEP for use in correcting PAT measurements by detecting low frequency vibrations created during a cardiac cycle, and a state estimator algorithm to identify signals indicative of aortic valve opening in those measured vibrations.

Abstract: Provided herein are devices, systems, platforms and methods for long-term, continuous monitoring of a biometric parameter of a subject using an in-ear pod.

Abstract: A congenital heart disease monitor utilizes a sensor capable of emitting multiple wavelengths of optical radiation into a tissue site and detecting the optical radiation after attenuation by pulsatile blood flowing within the tissue site. A patient monitor is capable of receiving a sensor signal corresponding to the detected optical radiation and calculating at least one physiological parameter in response. The physiological parameter is measured at a baseline site and a comparison site and a difference in these measurements is calculated. A potential congenital heart disease condition in indicated according to the measured physiological parameter at each of the sites or the calculated difference in the measured physiological parameter between the sites or both.

Abstract: A method for monitoring autoregulation includes, using a processor, using a processor to execute one or more routines on a memory. The one or more routines include receiving one or more physiological signals from a patient, determining a correlation-based measure indicative of the patient's autoregulation based on the one or more physiological signals, and generating an autoregulation profile of the patient based on autoregulation index values of the correlation-based measure. The autoregulation profile includes the autoregulation index values sorted into bins corresponding to different blood pressure ranges. The one or more routines also include designating a blood pressure range encompassing one or more of the bins as a blood pressure safe zone indicative of intact regulation and providing a signal to a display to display the autoregulation profile and a first indicator of the blood pressure safe zone.

Abstract: The present disclosure relates to computing blood pressure from images of the outer eye of an individual. Images of the outer eye of an individual obtained via a high magnification camera can be analyzed using computer vision to identify features associated with blood vessels in the outer eye, such as blood vessel size or diameter, blood vessel wall thickness, distance between vessels or vessel segments, area between vessels or vessel segments, and/or blood velocity through the vessels. These blood vessel features derived from images may be used to compute a blood pressure measure(s) for an individual through use of an artificial intelligence algorithm which relates the blood vessel features to blood pressure values.

Abstract: A blood pressure monitoring system may include an acoustic exciter configured to receive an electrical input signal and to produce an acoustic signal and an acoustic detector spaced apart from the acoustic exciter. The acoustic detector may be configured to detect the acoustic signal and to produce an electrical output signal. The acoustic exciter may be provided on a first substrate portion and the acoustic detector may be provided on a second substrate portion that is acoustically decoupled from the first substrate portion. The blood pressure monitoring system may also include a processor configured to determine a blood pressure measurement from the electrical output signal.

Abstract: The invention described provides a way to use video image to estimate the human artery blood pressure reducing or completely eliminating the need for human contact (non invasive). Since video images can be stored and transmitted, the estimation of the blood pressure can be performed locally, remotely and in real time or offline.

Abstract: A method for determining a pressure gradient between proximal and distal locations within a vasculature of a patient. The method includes deploying an ancillary device within the vasculature. The ancillary device integrates a proximal sensor at the proximal location and a distal sensor at the distal location. The method further includes deploying, via a stent graft delivery system, a stent graft within the vasculature to obtain a deployed stent graft. The ancillary device is independent from the stent graft delivery system and the stent graft. The method further includes outputting proximal pressure data from the proximal sensor and indicative of pressure at the proximal location and distal pressure data from the distal sensor and indicative of pressure at the distal location. The method also includes determining the pressure gradient using the proximal and distal pressure data.

Abstract: A blood pressure measuring device comprises a device body, an air bag, an air nozzle and a piston, an air pump is provided in the device body, a casing of the device body is provided with a mounting hole and an air channel connection hole communicating with the mounting hole, the air channel connection hole is communicated with an air outlet of the air pump, the piston is installed in the mounting hole, the piston includes a piston sealing portion capable of forming a seal with the mounting hole positioned above the air channel connection hole, the air nozzle includes a through hole communicating with the air bag, when the air nozzle is inserted into the mounting hole, the air nozzle presses the piston downward until the piston sealing portion is positioned below the air channel connection hole, the through hole is communicated with the air channel connection hole.

Abstract: An electronic device is provided. The electronic device includes a camera, and at least one processor, wherein the at least one processor is configured to extract at least one face region and at least one hand region from an image captured by the camera, to acquire a biosignal from each of the extracted at least one face region and hand region, to match the face region and the hand region in the image using the acquired biosignals, to identify a user by performing face recognition on the image while acquiring the biosignal, and to identify a command for controlling an operation of the electronic device based on the biosignal in the hand region matching the face region for the identified user.

Abstract: A monitoring device configured to be attached within a portion of an ear of a subject includes an elastomeric arm having opposite first and second end portions. A sensing element is located at the elastomeric arm second end portion and includes at least one energy emitter configured to direct energy at a target region of the ear and at least one detector configured to detect an energy response signal from the target region or a region adjacent the target region. The monitoring device is configured such that the elastomeric arm first end portion engages the ear at a first location within the ear and such that the elastomeric arm resiliently bends such that a surface of the sensing element is urged into contact with the ear at a second location within the ear.

Abstract: Provided are a method for calculating SIG-BF for a blood vessel site from an MRA image and a system for analyzing the risk of cerebrovascular disease and stroke using same. A method for analyzing the risk of cerebrovascular disease according to an embodiment of the present invention enables the risk of cerebrovascular disease to be predicted by calculating the SIG-BF of a blood vessel from the MRA image. Accordingly, accurate diagnosis and monitoring of cerebral infarction, cerebrovascular disease, cerebral hemorrhage, etc. can be achieved, the mid- to long-term prognosis can be determined and the optimal treatment or treatment method can be selected, and future risks can be predicted.

Abstract: An MRI image processing and analysis system may identify instances of structure in MRI flow data, e.g., coherency, derive contours and/or clinical markers based on the identified structures. The system may be remotely located from one or more MRI acquisition systems, and perform: error detection and/or correction on MRI data sets (e.g., phase error correction, phase aliasing, signal unwrapping, and/or on other artifacts); segmentation; visualization of flow (e.g., velocity, arterial versus venous flow, shunts) superimposed on anatomical structure, quantification; verification; and/or generation of patient specific 4-D flow protocols. A protected health information (PHI) service is provided which de-identifies medical study data and allows medical providers to control PHI data, and uploads the de-identified data to an analytics service provider (ASP) system. A web application is provided which merges the PHI data with the de-identified data while keeping control of the PHI data with the medical provider.

Abstract: Provided is a simple, portable, real-time, and in vivo THz imaging device for imaging a target, e.g., a tooth in the subject. Moreover, the scanning based THz imaging device is much sufficiently sensitive as compared with the common X-ray imaging device. Therefore, the scanning based THz imaging device has the potential to operate in the density for early detection problems such as dental caries or demineralization of the enamel in the teeth. Also provided is a method for diagnosing or imaging the target in the subject by using the scanning based THz imaging device of the present disclosure.

Abstract: A sensor circuit includes a transimpedance amplifier, a feedback network, and a readout circuit. The transimpedance amplifier has a first input for receiving a measured signal, a second input for receiving a reference signal, and an output. The feedback network includes a capacitor and a variable resistor each coupled between the output and the first input of the transimpedance amplifier. The readout circuit is coupled to the feedback network and has an output for providing a readout signal. In a conversion mode, the readout circuit provides the readout signal based on one sample of the output of the transimpedance amplifier. In an integration mode, the readout circuit provides the readout signal based on a plurality of samples of the output of the transimpedance amplifier.

Abstract: A method of determining the diameter of a luminal organ. The method utilizing the introduction of two different frequencies into the lumen of the organ via an impedance catheter/guidewire to obtain conductance measurements and not requiring a separate fluid injection. The method utilizes the presence of a fluid native to the luminal organ.

Abstract: A method for determining a location of an apparatus inside an imaging volume of an MRT system surrounded by a basic field magnet for creating a static basic magnetic field along a longitudinal axis and by a gradient coil is provided. The apparatus has a first conductor loop that runs within a loop plane. The method includes creating a magnetic alternating field in the imaging volume using the gradient coil. At least one measured value that depends on an induction voltage that is induced by a component of the alternating field at right angles to the longitudinal axis in the at least one conductor loop is determined using the at least one first conductor loop. A location of the apparatus inside an imaging volume is determined at least partly as a function of the at least one measured value and a predetermined magnetic field model for the gradient coil.

Abstract: The gastrointestinal capsule provides mechanical stimulation within the gastrointestinal tract. The capsule may be deployed in a subject's gastrointestinal tract orally by the subject ingesting the capsule. The capsule may mechanically stimulate any desired region within the gastrointestinal tract, including the stomach, small intestine, and large intestine. The mechanical stimulations provided by the capsule are applied to a portion of the inner walls or lining of a section of the gastrointestinal tract to simulate satiety.

Abstract: Systems and methods for measurement of end tidal carbon dioxide, including a device having a body and a tubular gas line. The body is adapted to be attached to a patient airway and has a first gas line securing portion which has an aperture through it and is adapted to secure the gas line to the body. The tubular gas line is secured in the aperture. The tubular gas line has a proximal portion extending from a proximal end of the aperture and has a proximal end which is adapted to be connected to an end tidal CO2 monitor. The tubular gas line also has a distal portion extending from a distal end of the aperture and having a distal end which provides an inlet for end tidal CO2 exhaled by a patient.

Abstract: A system and method for generating a metabolic dysfunction nourishment program comprises a computing device configured to obtain a metabolic component as a function of a user metabolic system, identify a metabolic panel as a function of the metabolic component, wherein identifying further comprises receiving a status grading, ascertaining a metabolic functional goal, and identifying the metabolic panel as a function of the status grading, metabolic functional goal, and metabolic component using a metabolic machine-learning model, determine an edible as a function of the metabolic panel, wherein determining further comprises receiving a nourishment composition from an edible directory, producing a nourishment demand as a function of the metabolic panel, and determining the edible as a function of the nourishment composition and nourishment demand using an edible machine-learning model, and generate a nourishment program as a function of the edible and a metabolic outcome using a nourishment machine-learning mo

Abstract: A method for operating an accessory device to capture calibration data. The method can include capturing an image of a portion of a user's body that includes the user's stoma and at least two reference locations, and storing distance scale information representative of a distance between the two reference locations. The method further includes processing the captured image, including: identifying the reference locations, identifying the stoma, and generating calibration data representative of one or more stoma parameters as a function of the identified reference locations, identified stoma and the distance scale information. The calibration data can be stored.

Abstract: A portable three-dimensional image measuring device according to various embodiments of the present disclosure may include a light source configured to output patterned light; a camera configured to generate a light field image of an object by receiving reflected light generated by reflecting the patterned light from the object; and an optical path control element configured to reflect the patterned light output from the light source so that the object is irradiated with the patterned light, and to transmit the reflected light reflected from the object so that the reflected light reaches the camera. An optical path of the patterned light output from the light source and irradiated onto the object and an optical path of the reflected light reflected from the object and reaching the camera may overlap coaxially in a section between the optical path control element and the object.

Abstract: A hearing device system for testing a user's hearing capability, comprises: a processing unit configured to determine a plurality of tones and an order of the tones; an acoustic output transducer configured to output audio signals; a tone generator configured to output the tones, where a first set of the plurality of tones will be audible to the user and a second set of the plurality of tones will be inaudible to the user; and a user interface or a communication unit configured to receive an indication from the user indicating an audible tone being perceived; wherein one of the tones comprises a new tone, and wherein the processing unit is configured to determine the new tone based on: whether a predefined number of preceding tones were audible or inaudible to the user, and an estimated probability of whether the new tone will be audible or inaudible to the user.

Abstract: Apparatus and method for determining the immittance of a middle ear for clinical- audiometric investigations in a wide range of frequencies at ambient pressure, based on MEMS microphone technology and on measuring the acoustic pressure wave and the corresponding acoustic velocity wave by means of a pressure-pressure probe.

Abstract: This invention is directed to towards methods of identifying a subject with insulin resistance. For example, this invention is drawn to adjusting C-peptide urinary excretion rate for average glucose concentration to identify a subject with insulin resistance.

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Abstract: An information processing apparatus comprising at least one processor, wherein the at least one processor is configured to: acquire a measured value, which is measured in a sample test, together with time information indicating a measurement time point of the measured value; acquire a monitoring value which is obtained by monitoring biological information having a correlation with the measured value; and associate the measured value with the monitoring value at the measurement time point indicated by the time information.

Abstract: Systems, methods, and apparatus for differential phase contrast microscopy by transobjective differential epi-detection of forward scattered light are provided. In some embodiments, a microscope objective comprises: a housing with mounting threads at a second end; optical components defining an optical axis, comprising: an objective lens mounted at a first end, configured to collect light from a sample placed in a field of view, the plurality of optical components create a pupil plane at a first distance along the optical axis at which rays having the same angle of incidence on the objective lens converge at the same radial distance from the optical axis; a photodetector within the housing offset from the optical axis at a second distance along the optical axis; and another photodetector within the housing at second distance along the optical axis and offset from the optical axis in the opposite direction from the first photodetector.

Abstract: Provided are systems and methods for determination of a concentration of one or more blood biomarkers of a human subject. The method including: determining, using a first machine learning model trained with a hemoglobin concentration (HC) changes training set, bit values from a set of bitplanes in a captured image sequence that represent the HC changes of the subject, the set of bitplanes being those that are determined to approximately maximize a signal-to-noise ratio (SNR), the HC changes training set including bit values from each bitplane of images captured from a set of subjects for which HC changes are known; determining, using a second machine learning model trained using a blood biomarkers training set, concentration of one or more blood biomarkers, the blood biomarkers training set including previously determined HC change signals from other subjects and one or more blood panels from those subjects as ground truth data.

Abstract: A detection device includes a sensor unit that has a detection area divided into a plurality of partial detection areas, a control circuit that has a first mode of acquiring data for each of the partial detection areas based on a detection value acquired from the partial detection area and a second mode of selecting the partial detection areas in which a signal strength of the data acquired in the first mode is relatively higher among the partial detection areas, and acquiring biometric data of an object to be detected based on a detection value acquired by coupling the selected partial detection areas in parallel, and an amplifying circuit configured to receive the detection value acquired in the second mode.

Abstract: The present invention is an in vivo non-invasive method and apparatus for the measurement of the arterial blood oxygen saturation status of a patient, the method is a generalized improvement on conventional pulse oximetry to correct for its skin pigmentation bias and significant errors in oxygen saturation assessment in the presence of methemoglobin. The method requires an additional red light sensor with an infrared long pass filter to conventional pulse oximetry, and utilizes red and infrared light and sensors to non-invasively measure the peripheral pulse optical plethysmograph waveforms (PPG) at three light wavelengths, red, long pass red and infrared, positioned over a finger, or ear or other extremity, and from the pulse oximetric ratio of ratios transforms the PPG measurements by a processing device that determines the subject's arterial blood oxygen saturation directly, without the need for an empirical correction as is required in conventional pulse oximetry.

Abstract: A pulse oximetry system for measuring at least one physiological parameter includes a wearable device configured to be secured to a subject's foot, a sensor hub that is removably securable to the wearable device, and a sensor strap connected to the sensor hub and configured to be wrapped around the subject's foot and secured to the wearable device. In some implementations, the wearable device is configured such that the cavity is positioned adjacent a bottom portion of the subject's foot. The system further includes one or more emitters arranged within the sensor hub and configured to face toward said bottom portion of the subject's foot and one or more detectors arranged within the sensor strap and configured to be positioned adjacent a top portion of the subject's foot.

Abstract: Flexible analyte sensors are provided. Flexible analyte sensors may be flexible continuous analyte sensors that facilitate continuous monitoring of an analyte such as blood glucose. The flexible analyte sensor may have a relatively flexible conductive or non-conductive core, may be formed from a plurality of substantially planar layers, or may be configured to transform from a freestanding sensor ex vivo to a non-freestanding sensor in vivo.

Abstract: A system is provided for monitoring glucose in a host, including a continuous glucose sensor that produces a data stream indicative of a host's glucose concentration and an integrated receiver that receives the data stream from the continuous glucose sensor and calibrates the data stream using a single point glucose monitor that is integral with the integrated receiver. The integrated receiver obtains a glucose value from the single point glucose monitor, calibrates the sensor data stream received from the continuous glucose sensor, and displays one or both of the single point glucose measurement values and the calibrated continuous glucose sensor values on the user interface.

Abstract: A point-of-care blood collection and dispensing device for use with a luer lock access device, the point-of-care collection and dispensing device including a distal engagement portion, wherein at least a part of the distal engagement portion is configured to engage a needle of the luer lock access device, and a sidewall portion, wherein at least part of the sidewall portion is formed of a flexible material capable of being compressed. The device also includes a fluid chamber configured to hold a blood sample, the fluid chamber bound at least partially by the distal engagement portion and the sidewall portion, as well as an opening, wherein the opening is sized and configured to dispense a small volume of the blood sample held within the fluid chamber when the sidewall portion is compressed.