Patents Issued in November 23, 2023
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Publication number: 20230371816Abstract: There is described a system for determining an atherosclerotic pathological tissue type of a coronary artery, the system comprising: an optical coherence tomography (OCT) imaging system being configured for acquiring an OCT image of tissue within said coronary artery; and a controller configured for: using a trained fully convolutional engine stored on said memory and having a plurality of convolutional layers with respective dilation rates different than unity, extracting pathological tissues regardless their type in at least a region of interest of said OCT image; using a trained auto-encoder classification engine stored on said memory and having a layer characterized with a sparsity regularization parameter, determining an atherosclerotic pathological tissue type associated to said region of interest of said OCT image based on said extracted pathological tissues; and outputting said atherosclerotic pathological tissue type of said coronary artery.Type: ApplicationFiled: October 5, 2021Publication date: November 23, 2023Inventors: Atefeh ABDOLMANAFI, Luc DUONG, Nagib DAHDAH, Ragui IBRAHIM
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Publication number: 20230371817Abstract: An endoscope system according to the present invention includes: an illumination light source that emits illumination light for illuminating an object; a therapeutic light source that emits therapeutic light for causing a photoreactive reagent accumulated in a treatment target site to react; a guide light source that emits guide light having a wavelength shorter than a wavelength band of the therapeutic light source; an imager that captures an optical image, the imager including an optical filter that cuts light in the wavelength band of the therapeutic light and transmits a part of white light, the guide light, and fluorescence emitted by the reagent; a controller that controls emission timings of the illumination light source, the therapeutic light source, and the guide light source; and an image processor that generates an image on the basis of an optical image obtained by light emitted from the illumination light source, the therapeutic light source, and the guide light source, in which the controller cauType: ApplicationFiled: October 24, 2022Publication date: November 23, 2023Applicant: OLYMPUS CORPORATIONInventors: Masaru MIZUNAKA, Yasunobu IGA, Takeshi SUGA, Chikashi OTA
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Publication number: 20230371818Abstract: A hyperspectral characteristic band selection method and an active hyperspectral imaging device using the same. The method using a virtual dimension algorithm to calculate a number of endmembers of a hyperspectral image of a predetermined disease, and using between 1 time and 2 times the number of endmembers as a number of predetermined selected bands, and then selecting characteristic bands with a number matching the number of selected bands from a plurality of spectral bands in the image. The device comprises a base, light sources and a sensing portion, the light sources are respectively disposed on the base, bands emitted by the light sources are configured according to the characteristic bands calculated by the method. The sensing portion is disposed on the base and spaced apart from the light sources for receiving reflected light from an external target object irradiated by the light sources to obtain a hyperspectral image.Type: ApplicationFiled: May 20, 2022Publication date: November 23, 2023Inventors: Hsian-Min CHEN, Yi-Ming CHEN, YI-JING SHEEN, Hsin-Che WANG, TSU-TE HAO
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Publication number: 20230371819Abstract: A device 2300 to be inserted into the ear canal having at least two thermistors 205, 207 for observing a temperature gradient in the ear canal of a user, and a photoplethysmography sensor 215, 217. Changes in the temperature gradient, heart rate and magnitude of the pulse are monitored for determining the risk of the user in facing an imminent heat stroke.Type: ApplicationFiled: August 3, 2021Publication date: November 23, 2023Inventor: Ming Yip Wallace WONG
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Publication number: 20230371820Abstract: A contactless sensor includes a cardiac beamformer, a wireless-to- seismocardiogram translator, and an automatic labeler. The cardiac beamformer determines at least one beam for receiving wireless signals generated based on movement of a heart. The at least one beam is generated based on phase information and a heart signal extracted from a time-domain signal generated from one or more receiver elements. The wireless-to-seismocardiogram translator implements a convolutional neural network to transform time-series data detected from the at least one beam to a seismocardiogram. The automatic labeler identifies and labels one or more micro-cardiac events in the time-series data. The cardiac beamformer may be considered an optional feature in one or more implementations.Type: ApplicationFiled: August 27, 2021Publication date: November 23, 2023Applicant: Massachusetts Institute of TechnologyInventors: Unsoo HA, Fadel ADIB
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Publication number: 20230371821Abstract: The present invention provides a method, a device, an electronic apparatus, and a storage medium for processing multi-modal physiological signals, which relates to the field of health engineering. The method comprises: acquiring continuous target multi-modal physiological signals, the target multi-modal physiological signals comprise at least three target physiological signals of a target temperature signal, a target impedance plethysmogram (IPG) signal, a target electrocardiogram (ECG) signal, a target photoplethysmogram (PPG) signal and a target ultrasound signal; determining a continuous physiological information of a target subject, especially a continuous blood pressure information, according to the continuous target multi-modal physiological signals.Type: ApplicationFiled: November 5, 2022Publication date: November 23, 2023Inventors: Yuanting ZHANG, Ting XIANG, Zijun LIU, Nan JI
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Publication number: 20230371822Abstract: A signal acquisition system configured to track a physiologic signal of a person includes a first accelerometer having a first accelerometer channel configured to obtain information of a physiologic signal. The physiologic signal is obtained extracorporeally. A control circuit receives data from the first accelerometer channel to identify, using at least one harmonic template, a base frequency of the physiologic signal. The system applies a filter to establish a tracking signal initialized with the identified base frequency and stores and/or transmits the tracking signal as a representation of the physiologic signal. The system alternatively performs filtration and estimation operations to extract physiologic information including heart rate, heart rate variability, and respiration rate from the physiologic signal.Type: ApplicationFiled: September 23, 2020Publication date: November 23, 2023Inventors: Christoph Kaemmerer, Johannes Traa
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Publication number: 20230371823Abstract: The present disclosure may be embodied as methods and/or systems for non-contact measuring of an on-body and/or inside-body motion of an individual. A sensing signal is provided within a near-field coupling range of a motion to be measured. In this way, a measurement signal may be generated as the sensing signal modulated by the motion. The sensing signal may be an ID-modulated signal. In some embodiments, the sensing signal is a backscattered RFID link provided a wireless tag. A downlink signal may be provided to power the wireless tag. The sensing signal may be a harmonic of the downlink signal. The measurement signal is detected. The motion is measured based on the measurement signal. The measurement signal may be detected as far-field radiation after transmission through a source of the motion. The measurement signal may be detected as reflected from a source of the motion as antenna reflection.Type: ApplicationFiled: July 21, 2023Publication date: November 23, 2023Inventors: Xiaonan Hui, Edwin C. Kan
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Publication number: 20230371824Abstract: In one example aspect, a computer-implemented method includes receiving biometrics data for a user; determining, based on the biometrics data, a baseline root-mean square (RMS) value prior to performance of a medical maneuver by the user; determining a minimum RMS value of the biometrics data during the medical maneuver; calculating a ratio between the minimum RMS value and the baseline RMS value to generate a minimum RMS ratio; and storing or outputting the minimum RMS ratio.Type: ApplicationFiled: October 12, 2021Publication date: November 23, 2023Applicant: THE JOHNS HOPKINS UNIVERSITYInventor: Harry A. SILBER
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Publication number: 20230371825Abstract: A smartwatch-type individual medical monitoring device includes a main body with a display screen, a bracelet linked to the main body, a processor and a measurement instrument positioned opposite a radial artery of the wrist of the user. The measurement instrument includes a first sensor to continuously measure the oxygen level, a second sensor measures the heart rate by measuring the vibrations of the blood flow at the radial artery, and a third sensor measures the ascending and descending blood flows at the radial artery. The processor is configured to: acquire the measured data of the three sensors, analyze the measured oxygen level, analyze the number of measured vibrations of the blood flow, analyze the measured ascending and descending blood flows, output detection of an anomaly based on analysis of oxygen level, heart rate and ascending and descending blood flows, and store the measured data of the three sensors.Type: ApplicationFiled: August 7, 2023Publication date: November 23, 2023Inventors: Hayame Bouyahia, Samira Kerrouche
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Publication number: 20230371826Abstract: A non-invasive method and an apparatus for measuring blood pressure of a subject. The method includes capturing and processing a first input and a second input to detect a first peak value (Tim (ECG)) and a second peak value (Tim (PPG)). The method includes calculating a pulse transit time (PTT) based on the first peak value and the second peak value, and a pulse wave velocity (PWV) based on the PTT and an arm length of the subject. Further, determining whether the PWV is associated with predefined coefficient values stored in the memory. In response, initiating a calibration before measuring the blood pressure under varying conditions of the subject to generate a plurality of coefficients based on one or more predefined blood pressure values or determining the blood pressure based on an association of the pulse wave velocity and the predefined coefficient values.Type: ApplicationFiled: August 2, 2022Publication date: November 23, 2023Inventors: SRIKANTH CHANDRASHEKAR, KEWAL DESHPANDE, ABHINAV SHUBHAM
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Publication number: 20230371827Abstract: Machine learning techniques for estimating an indication of carotid-femoral pulse wave velocity (CFPWV) and/or vascular age (VA) of a subject from an arterial waveform previously measured at a single site by an arterial waveform acquisition device coupled to the subject, the method comprising using at least one computer hardware processor to perform: obtaining the arterial waveform, the arterial waveform comprising a plurality of portions corresponding to a respective plurality of heartbeats of the subject; generating a representative heartbeat waveform from the arterial waveform; and providing the representative heartbeat waveform as input to a trained machine learning model to produce a corresponding output indicative of the CFPWV of the subject.Type: ApplicationFiled: April 11, 2023Publication date: November 23, 2023Applicant: Cardiovascular Engineering, Inc.Inventors: Gary F. Mitchell, John D. Gotal
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Publication number: 20230371829Abstract: A portable blood pressure measurement device with a removeable/replaceable cuff is disclosed. The device can be capable of wirelessly interacting with a secondary device, such as a cell phone, to measure blood pressure of a patient and configurable to fold into a low profile storage configuration. The removable cuff is sized and configured for wrapping around the limb of a subject the cuff further having an inflatable bladder formed integrally therein; one or more tubes positioned within the cuff in communication with the inflatable bladder; an exhaust valve; a housing connected to the cuff wherein the housing houses one or more of a controller, a memory, a pump, a power supply, and a motor. A transmitter can be provided for wirelessly transmitting blood pressure data to a second device. Operation of the device is furthermore changeable in response to a detected cuff size.Type: ApplicationFiled: May 18, 2023Publication date: November 23, 2023Applicant: QARDIO, INC.Inventor: Rosario IANNELLA
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Publication number: 20230371830Abstract: A blood pressure tracking and detection system. The pressure application and release module is configured to apply a pressure to a detected part of a target user according to a pressure application instruction. The pressure application and release module is further configured to release the pressure on the detected part of the target user according to a pressure release instruction. The signal obtaining module is connected to the pressure application and release module. The signal obtaining module is configured to obtain a photoplethysmography (PPG) signal and a pressure signal of the detected part of the target user. The blood pressure tracking and detection module is connected to the signal obtaining module. The blood pressure tracking and detection module is configured to determine an initial blood pressure of the detected part of the target user according to a PPG signal and a pressure signal in a pressure application and release cycle.Type: ApplicationFiled: October 5, 2022Publication date: November 23, 2023Inventors: Ruijuan Chen, Shumian Xiao, Cong Wang, Huiquan Wang
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Publication number: 20230371831Abstract: a method for predicting blood pressure by fusing calibrated photoplethysmography (PPG) signal data includes obtaining real-time PPG signal data, calibrated PPG signal data, calibrated diastolic blood pressure data, and systolic blood pressure data; using a CNN+ANN model to calculate the relative blood pressure data, and generating an ANN output tensor, according to the calibrated diastolic blood pressure and systolic blood pressure data, and the ANN output tensor, performing blood pressure data calculation and generating a blood pressure tensor; if the predicted type information is a first type, performing a mean value calculation according to the blood pressure tensor, and generating diastolic blood pressure prediction data and systolic blood pressure prediction data; if the predicted type information is a second type, performing data extraction processing on the blood pressure tensor, and generating a diastolic blood pressure prediction data sequence and a systolic blood pressure prediction data sequence.Type: ApplicationFiled: April 19, 2021Publication date: November 23, 2023Inventors: Jun Cao, Biying Zhang, Sihan Wang, Zejian Wu
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Publication number: 20230371832Abstract: The techniques described herein relate to a head-mounted device that includes a frame, a motion sensor coupled to the frame, and a processor in communication with the motion sensor. The processor is configured by instructions to receive motion signals captured by the motion sensor, determine when to extract features from the motion signals, extract the features from the motion signals, generate a signal image from the features extracted from the motion signals, and process the signal image to output one or more health metrics.Type: ApplicationFiled: May 19, 2022Publication date: November 23, 2023Inventors: Dongeek Shin, Shwetak N. Patel
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Publication number: 20230371834Abstract: A diagnostic manometry device comprises a catheter including a plurality of lumens, a fluid charger configured to operatively couple with the catheter, and a charging mechanism for moving fluid simultaneously from fluid pressure chambers of the plurality of fluid pressure chambers into the respective lumens of the plurality of lumens when the catheter is operatively coupled with the fluid charger. Each fluid pressure chamber of the plurality of fluid pressure chambers is configured to be in fluid communication with a respective lumen of the plurality of lumens when the catheter is operatively coupled with the fluid charger. Each pressure sensor of the plurality of pressure sensors is located and configured to measure a fluid pressure change in a respective fluid pressure chamber of the plurality of fluid pressure chambers. Additional manometry devices and methods of forming a manometry device are also disclosed.Type: ApplicationFiled: May 17, 2023Publication date: November 23, 2023Inventors: Albert Meek, Ryan Bernier, Julian Peters, Andrê Tremblay, Calvin Turland, Jessica Dakkak, Louis-Simon Guay, Benoit Thibauit
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Publication number: 20230371836Abstract: A medical apparatus includes a probe, which includes an insertion tube configured for insertion into a body cavity of a patient, and a distal assembly, which is connected distally to the insertion tube and includes a plurality of electrodes, which are configured to contact tissue within the body cavity. The apparatus further includes an electrical signal generator, which is configured to apply electrical pulses to a group of two or more of the electrodes with an amplitude sufficient to irreversibly electroporate the tissue contacted by the electrodes in the group, and a controller, which is coupled to measure a change in an electrical impedance between an electrode in the group and a further electrode as a result of application of the electrical pulses and to output a measure of ablation of the tissue responsively to the measured change in the electrical impedance.Type: ApplicationFiled: May 18, 2022Publication date: November 23, 2023Inventors: Assaf Govari, Andres Claudio Altmann, Lilah Marziano
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Publication number: 20230371837Abstract: The invention presents an electrodermal apparatus comprising at least two electrodes (10), each of which is configured to be in contact with a dermal region, and an electronic circuit comprising an analog-to-digital converter and a processor that is configured to execute computer-executable instructions in order to bias the electrodes (10), to measure the current flowing between pairs of electrodes (10), to apply digital preprocessing to the measured electrical signals and to determine the conductance of the dermal layer, wherein the sensor further comprises an accelerometer, delivering electrical signals to the processor, the preprocessing taking into account the level of the signals that are delivered by the accelerometer.Type: ApplicationFiled: September 23, 2021Publication date: November 23, 2023Inventor: Yann FRACHI
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Publication number: 20230371838Abstract: Apparatus (30) for detecting motion of a device (1) for electrical stimulation of a subject is described. The apparatus (30) comprises a motion detector (2) to detect the motion of the device (1) and generate a motion output signal in response to the detected motion. The motion output signal is indicative of the amount of detected motion. A processor (21) is coupled to the motion detector (20). The processor (21) receives (72) the motion output signal from the motion detector (20) and generates a first processor output signal in response to the received motion output signal. An output device (14, 26) is coupled to the processor (21). The output device (14, 26) receives the first processor output signal from the processor (21) and generates a first output signal in response to the received first processor output signal.Type: ApplicationFiled: August 10, 2021Publication date: November 23, 2023Applicant: Actegy LimitedInventor: Anno Jakob Koetje
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Publication number: 20230371840Abstract: Provided is an MR/PET integrated imaging plug-in device that may be inserted into an MM system without requiring modifications to the MRI system, including: a to-be-detected object holder at the magnetic field generated by the magnetic field generation structure, and configured to carry the to-be-detected object; a PET detection component configured to detect a PET image signal from the to-be-detected object; a magnetic resonance receiving coil configured to generate a magnetic resonance image of the to-be-detected object a signal amplification component. The PET detection component is movable relative to the to-be-detected object holder to align or leave the to-be-detected object.Type: ApplicationFiled: September 27, 2020Publication date: November 23, 2023Inventors: Haoqin Zhu, Jin Su, Gong Zhang
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Publication number: 20230371842Abstract: A wireless circuit includes a housing, such as a hermetic housing, and at least one antenna coil wound about a coil axis within the housing. The coil axis may be substantially parallel to at least one wall of the housing, wherein the wall parallel to the coil axis is substantially thinner than other walls of the housing.Type: ApplicationFiled: January 9, 2023Publication date: November 23, 2023Inventors: Harry Rowland, Michael Nagy
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Publication number: 20230371843Abstract: Embodiments disclosed herein improve digital stethoscopes and their application and operation. A first method detects of a respiratory abnormality using a convolution. A second method counts coughs for a patient. A third method predicts a respiratory event based on a detected trend. A fourth method forecasts characteristics of a future respiratory event. In a fifth embodiment, a base station is provided for a digital stethoscope.Type: ApplicationFiled: May 19, 2023Publication date: November 23, 2023Applicant: Sonavi Labs, Inc.Inventor: Ian Mitra McLANE
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Publication number: 20230371844Abstract: Apparatus for passing exhaled gasses from a mouth of a patient to a gas analyzer, the apparatus comprising: a pacifier comprising a distal end, a proximal end and an opening extending from the distal end to the proximal end, wherein the distal end comprises a nipple configured to be inserted into the mouth of the patient and the proximal end comprises a base configured to be positioned against the mouth of the patient; and a connector for connecting the pacifier to the gas analyzer.Type: ApplicationFiled: April 20, 2023Publication date: November 23, 2023Inventors: Michael Schinis, Jason Schinis
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Publication number: 20230371846Abstract: A tremor suppression device includes a garment wearable on an anatomical region and including electrodes contacting the anatomical region when the garment is worn on the anatomical region, and an electronic controller configured to: detect electromyography (EMG) signals as a function of anatomical location and time using the electrodes; identify tremors as a function of anatomical location and time based on the EMG signals; and apply neuromuscular electrical stimulation (NMES) at one or more anatomical locations as a function of time using the electrodes to suppress the identified tremors.Type: ApplicationFiled: August 4, 2023Publication date: November 23, 2023Inventors: Gaurav Sharma, Patrick Ganzer
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Publication number: 20230371847Abstract: An apparatus for detecting at least one parameter, in particular kinetic, in relation to a human/animal heart/myocardium, especially during surgical operations; comprising a detector for detecting spatial or mechanical, movements of said heart/myocardium, and a controller for processing data provided by the detector for providing at least one corresponding parameter, in particular kinetic, in relation to the heart/myocardium. The detector is adapted to detect a distance, or depth, i.e. a variation in distance, or depth, of one or more points of said heart/myocardium, particularly one or more points of a corresponding surface or wall of the heart/myocardium by the detector.Type: ApplicationFiled: September 22, 2021Publication date: November 23, 2023Inventors: Giacomo ROZZI, Enrico LA ROSA, Francesco BARRESI
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Publication number: 20230371849Abstract: Provided is a gait information generation device including an acquisition unit that acquires gait data including time-series data of a foot position of a subject, a detection unit that detects a start point and an end point of a gait cycle from the time-series data of the foot position included in the gait data, a calculation unit that calculates a first movement amount component related to the start point and a second movement amount component related to the end point, a gait information generation unit that generates gait information about a gait movement path of the subject using the calculated first movement amount component and the calculated second movement amount component, and an output unit that outputs the generated gait information.Type: ApplicationFiled: May 9, 2023Publication date: November 23, 2023Applicant: NEC CorporationInventors: Kazuki IHARA, Kenichiro FUKUSHI, Zhenwei WANG, Hiroshi KAJITANI, Fumiyuki NIHEY, Chenhui HUANG, Yoshitaka NOZAKI, Kentaro NAKAHARA
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Publication number: 20230371850Abstract: Systems and methods described provide dynamic and intelligent ways to change the required level of user interaction during use of a monitoring device. The systems and methods generally relate to real time switching between a first or initial mode of user interaction and a second or new mode of user interaction. In some cases, the switching will be automatic and transparent to the user, and in other cases user notification may occur. The mode switching generally affects the user's interaction with the device, and not just internal processing. The mode switching may relate to calibration modes, data transmission modes, control modes, or the like.Type: ApplicationFiled: July 21, 2023Publication date: November 23, 2023Applicant: Dexcom, Inc.Inventors: Naresh C. Bhavaraju, Michael A. Bloom, Leif N. Bowman, Alexandra Lynn Carlton, Katherine Yerre Koehler, Hari Hampapuram, Jonathan Hughes, Lauren Hruby Jepson, Apurv Ullas Kamath, Anna Leigh Rack-Gomer, Peter C. Simpson, Stephen J. Vanslyke
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Publication number: 20230371852Abstract: Methods and systems for performing optical imaging are provided. An optical imaging system includes a light source configured to generate a spatially-distributed illumination beam of temporally-varying light and a detector configured to detect light resulting from an interaction between the illumination beam and a sample. The system further includes a processor configured to determine spatial and temporal characteristics of the detected light and generate a representation of the sample based on the determined spatial and temporal characteristics.Type: ApplicationFiled: May 23, 2023Publication date: November 23, 2023Inventors: Qianqian Fang, Miguel Adrian Mireles Nunez, Edward Xu
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Publication number: 20230371853Abstract: An oximeter probe includes a probe unit or a base unit and a probe tip where the probe tip has a number of sources and detectors that can be accessed individually or in differing combinations for measuring tissue oxygen saturation at different tissue depth in tissue. A processor of the oximeter probe controls a multiplexer that is coupled to the detectors for selectively collecting measurement information from the detectors via the multiplexer. The oximeter probe is user programmable via one or more input devices on the oximeter probe for selecting the particular sources and detectors to collect measurement information from by the processor.Type: ApplicationFiled: July 25, 2023Publication date: November 23, 2023Inventors: Kate LeeAnn Bechtel, Jennifer Elizabeth Keating, Scott E. Coleridge
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Publication number: 20230371854Abstract: An oximeter device has a replaceable probe tip. The probe tip can be removed or detached from the probe unit and discarded. A replacement probe tip can be attached to the probe tip. The replaceable probe tip allows the probe unit to be reused many times, each time with new sterile probe tip.Type: ApplicationFiled: August 1, 2023Publication date: November 23, 2023Inventors: Joseph Heanue, Scott E. Coleridge, Sophia Elizabeth Berger
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Publication number: 20230371855Abstract: The present invention provides a method of evaluating vascular struggle in an aging human tissue and aging level during muscle exertion.Type: ApplicationFiled: May 18, 2023Publication date: November 23, 2023Applicant: NuLiv Science USA, Inc.Inventors: Chia-Hua Kuo, Michael, Chang Yu Wang
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Publication number: 20230371856Abstract: A medical device for detecting at least one analyte in a body fluid is disclosed.Type: ApplicationFiled: August 1, 2023Publication date: November 23, 2023Applicant: Roche Diabetes Care, Inc.Inventor: Helmut Walter
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Publication number: 20230371857Abstract: A medical device for detecting at least one analyte in a body fluid is disclosed.Type: ApplicationFiled: August 2, 2023Publication date: November 23, 2023Applicant: Roche Diabetes Care, Inc.Inventor: Helmut Walter
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Publication number: 20230371858Abstract: A device for providing passive, wireless, in vivo detection of post-surgical infection in a surgical implant or prosthesis is provided. The device includes at least one magnetoelastic-based sensor associated with the implant or prosthesis. At least one magnetoelastic-based sensor is a differential sensor. Also, the differential sensor comprises a reference element and a sensing element.Type: ApplicationFiled: May 23, 2023Publication date: November 23, 2023Inventors: Tao Li, Jiaxin Jiang, Krithika Sureshkumar, Chandrashekhar Choudhary, Henry Claude Sagi, Chia-Ying Lin, Michael Archdeacon
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Publication number: 20230371859Abstract: A medical device for detecting at least one analyte in a body fluid, a method for assembling the medical device and a method of using the medical device are disclosed. The medical device comprises: an analyte sensor having an insertable portion; an insertion cannula receiving the insertable portion of the analyte sensor; an electronics unit connected with the analyte sensor; and a housing comprising an electronics compartment receiving the electronics unit and—a sensor compartment receiving the analyte sensor, the sensor compartment forming a sealed compartment receiving the insertable portion of the analyte sensor, the sealed compartment comprising detachable upper and lower caps, the lower cap configured for detachment before insertion, the insertion cannula being attached to the upper cap, wherein detaching the upper cap after insertion removes the insertion cannula, wherein the electronics compartment at least partially surrounds the sensor compartment.Type: ApplicationFiled: July 31, 2023Publication date: November 23, 2023Applicant: Roche Diabetes Care, Inc.Inventor: Helmut Walter
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Publication number: 20230371860Abstract: A medical device for detecting at least one analyte in a body fluid, a method for assembling the medical device and a method of using the medical device are disclosed. The medical device comprises: an analyte sensor having an insertable portion; an insertion cannula receiving the insertable portion of the analyte sensor; an electronics unit connected with the analyte sensor; and a housing comprising an electronics compartment receiving the electronics unit and-a sensor compartment receiving the analyte sensor, the sensor compartment forming a sealed compartment receiving the insertable portion of the analyte sensor, the sealed compartment comprising detachable upper and lower caps, the lower cap configured for detachment before insertion, the insertion cannula being attached to the upper cap, wherein detaching the upper cap after insertion removes the insertion cannula, wherein the electronics compartment at least partially surrounds the sensor compartment.Type: ApplicationFiled: July 31, 2023Publication date: November 23, 2023Applicant: Roche Diabetes Care, Inc.Inventor: Helmut Walter
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Publication number: 20230371861Abstract: A medical device for detecting at least one analyte in a body fluid, a method for assembling the medical device and a method of using the medical device are disclosed. The medical device comprises: an analyte sensor having an insertable portion; an insertion cannula receiving the insertable portion of the analyte sensor; an electronics unit connected with the analyte sensor; and a housing comprising an electronics compartment receiving the electronics unit and a sensor compartment receiving the analyte sensor, the sensor compartment forming a sealed compartment receiving the insertable portion of the analyte sensor, the sealed compartment comprising detachable upper and lower caps, the lower cap configured for detachment before insertion, the insertion cannula being attached to the upper cap, wherein detaching the upper cap after insertion removes the insertion cannula, wherein the electronics compartment at least partially surrounds the sensor compartment.Type: ApplicationFiled: August 1, 2023Publication date: November 23, 2023Applicant: Roche Diabetes Care, Inc.Inventor: Helmut Walter
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Publication number: 20230371862Abstract: This disclosure relates to an apparatus for glucose-sensing that address interference of ascorbic acid and acetaminophen. The apparatus includes a first electrode capable of oxidizing glucose and at least one of ascorbic acid and acetaminophen. The apparatus further includes a second electrode capable of oxidizing at least one of ascorbic acid and acetaminophen but not capable of oxidizing glucose. The first electrode includes a deposit of irregularly shaped bodies that are formed of numerous nanoparticles having a generally oval or spherical shape with a length ranging between about 2 nm and about 5 nm.Type: ApplicationFiled: August 2, 2023Publication date: November 23, 2023Inventors: Sejin Park, Rae Kyu Chang, Hankil Boo
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Publication number: 20230371865Abstract: The disclosed apparatus, systems and methods relate to the collection of bodily fluids through the use of gravity and microfluidic properties by way of a collector. The collector can make use of microfluidic networks connected to collection sites on the skin of a subject to gather and shuttle blood into a reservoir by a combination of capillary action and gravitational forces. The collected fluid is moved through the microfluidic networks and into the reservoir by a variety of approaches.Type: ApplicationFiled: February 13, 2023Publication date: November 23, 2023Inventors: Erwin BERTHIER, Ben CASAVANT, Ben MOGA
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Publication number: 20230371866Abstract: A blood draw system including a blood draw device having an actuator and a blood draw tube operably coupled to the actuator, the actuator configured to selectively advance the blood draw tube through a catheter of a vascular access device when the blood draw device is coupled to the vascular access device. The system also includes an extension tube extending from the blood draw device, the proximal extension tube being in fluid communication with the blood draw tube, and a proximal connector positioned at a proximal end of the extension tube. Furthermore, the system includes an initial blood volume diversion device positioned in-line with the extension tube between the blood draw device and the proximal connector, wherein the initial blood volume diversion device includes a diversion and isolation chamber configured to receive and hold an initial volume of blood drawn through the extension tube by the blood draw device.Type: ApplicationFiled: May 17, 2023Publication date: November 23, 2023Inventor: Jonathan Karl Burkholz
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Publication number: 20230371867Abstract: A blood draw system including a blood draw device having an actuator and a blood draw tube operably coupled to the actuator, wherein the actuator is configured to selectively advance the blood draw tube through a catheter of a vascular access device, and an extension tube extending from the blood draw device, wherein the extension tube is in fluid communication with the blood draw tube of the blood draw device. The system also includes a dual port adapter coupled to a proximal end of the extension tube, wherein the dual port adapter includes a first port and a second port, and a vented flashback and diversion chamber coupled to one of the first port and the second port, wherein the vented flashback and diversion chamber is configured to receive and hold an initial volume of blood drawn through the extension tube by the blood draw device.Type: ApplicationFiled: May 17, 2023Publication date: November 23, 2023Inventor: Jonathan Karl Burkholz
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Publication number: 20230371868Abstract: A blood draw device for use with a peripheral intravenous catheter (PIVC) includes a catheter having a proximal end, a distal end, and a sidewall therebetween defining a lumen, an introducer having a proximal end, a distal end, and a sidewall therebetween defining an inner volume configured to movably receive the catheter, with the introducer defining a longitudinal axis, and an actuator movably coupled to the introducer and connected to the catheter. The actuator having a first portion disposed outside of the introducer and a second portion disposed in the inner volume of the introducer, with the catheter having a first portion extending parallel to the longitudinal axis of the introducer and a second portion extending oblique to the longitudinal axis of the introducer.Type: ApplicationFiled: May 19, 2023Publication date: November 23, 2023Inventors: Megan S. Scherich, Weston F. Harding, Evan Barbour VandenBrink, John M. Lackey, Serena Robinson Agrawal
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Publication number: 20230371869Abstract: Apparatus of a multipurpose fluid extraction device for diagnostics and method of use are disclosed. The apparatus includes a fluid extraction system, wherein the fluid extraction system is configured to extract a fluid from a user, a microfluidic assembly, wherein the microfluidic assembly is configured to provide a flow of extracted fluid, where the microfluidic assembly includes a microfluidic channel, a photonic sensor, wherein the photonic sensor is configured to output a sensor signal to a reader device that is configured to detect one or more characteristics of the extracted fluid as a function of the sensor signal, an assay component fluidically connected to the microfluidic assembly, wherein the assay component is configured for testing the extracted fluid and a fluid collecting reservoir fluidically connected to the microfluidic assembly, wherein the fluid collecting reservoir is configured to collect the extracted fluid from the microfluidic assembly.Type: ApplicationFiled: May 18, 2023Publication date: November 23, 2023Applicant: SiPhox, Inc.Inventors: Michael Dubrovsky, Diedrik Rene Vermeulen
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Publication number: 20230371870Abstract: A portable smart device designed to be held by a user or worn by the user for determining a quality of a meditation session. The portable smart device including a heart rate sensor configured to detect heart rate of the user and output a heart rate signal, and an electronic computing unit coupled to the heart rate sensor. The electronic computing unit including a processor configured to analyze the heart rate signal of the user during the meditation session to determine two or more physiological parameters including at least one of breathing rate, breathing rate variability, heart rate, heart rate variability and vagal tone, and combine the two or more physiological parameters to determine a meditation session quality index (SQI) that indicates the quality of the meditation session.Type: ApplicationFiled: October 13, 2021Publication date: November 23, 2023Inventor: Anthony C. Warren
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Publication number: 20230371872Abstract: A method of estimating attention comprises: receiving encephalogram (EG) data corresponding to signals collected from a brain of a subject synchronously with stimuli applied to the subject. The EG data are segmented into segments, each corresponding to a single stimulus. The method also comprises dividing each segment of the EG data into a first time-window having a fixed beginning relative to a respective stimulus, and a second time-window having a varying beginning relative to the respective stimulus. The method also comprises processing the time-windows to determine the likelihood for a given segment to describe an attentive state of the brain.Type: ApplicationFiled: August 25, 2021Publication date: November 23, 2023Applicant: InnerEye Ltd.Inventors: Yuval HARPAZ, Amir B. GEVA, Leon Y. DEOUELL, Sergey VAISMAN, Yaar SHALOM, Michael OTSUP, Yonatan MEIR
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Publication number: 20230371873Abstract: The present disclosure relates to a wearable device and systems/methods relating to the device. Certain embodiments may include two flexible wings and a bridge connecting the two wings. In some embodiments, the upper surface of the bridge can be non-adhesive and uncoupled to the flexible wing such that the flexible wing can be decoupled from the bridge when the adhesive is adhered to the surface of a user.Type: ApplicationFiled: August 1, 2023Publication date: November 23, 2023Inventors: Jeffrey Joseph Abercrombie, II, Genaro Sebastian Sepulveda, Shena Hae Park, Ryan James Wensley, James Kihyun Lee, Thomas Burnell Reeve, III
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Publication number: 20230371874Abstract: The present disclosure relates to a wearable device that includes a housing, battery terminal connector, conductive traces, and an insulator for recording signals. The device may include a housing enclosing a circuit board and a battery. The device may include two conductive traces electrically connected to terminals of the battery and an insulator separating the conductive traces. The battery terminal connector can present both the conductive traces to the outer surface for coupling to a circuit board. The device can assess the physiological signals to infer a likelihood of arrhythmia of a user.Type: ApplicationFiled: August 1, 2023Publication date: November 23, 2023Inventors: Jeffrey Joseph Abercrombie, II, Genaro Sebastian Sepulveda, Shena Hae Park, Ryan James Wensley, James Kihyun Lee, Thomas Burnell Reeve, III
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Publication number: 20230371876Abstract: A method for determining a lowest stimulation threshold current level in a group of channels of a neuromonitoring device. The method includes stimulating tissue at a current level from a predetermined range of current levels as a sequence of pulses delivered at a frequency. The stimulating includes increasing the current level of each pulse in the sequence of pulses from an immediately preceding pulse by a first current increment. The method includes determining that a first evocation pulse from the sequence of pulses evokes a first muscular response. The method includes stimulating the tissue with a second evocation pulse from the sequence of pulses to evoke a second muscular response. The stimulating includes decreasing the frequency of the delivery of each pulse in the sequence of pulses and increasing the current level of each pulse in the sequence of pulses from the immediately preceding pulse by a second current increment.Type: ApplicationFiled: July 14, 2023Publication date: November 23, 2023Inventors: Richard A. O'Brien, Gregg Johns, Robert SNOW, James E. Gharib
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Publication number: 20230371877Abstract: A method for analyzing myocardial ischemia in resting electrocardiogram comprises establishing the database, grouping in a database, determining the threshold value for the group, processing the to-be-determined resting electrocardiogram, and determining the stenosis degree of the coronary artery.Type: ApplicationFiled: July 18, 2022Publication date: November 23, 2023Inventors: Chun-Lin Wang, Chiu-Chi Wei, Pin-Hsiang Chang